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Des Powe

Research Profile

Disorders

Chemicals & Drugs

Procedures

Anatomy

Basement Membrane

Concepts & Ideas

Physiology

Gene Expression Regulation, Neoplastic

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Publications

TOP 3
Stéphanie A-S Laversin; Geng Li; Stéphanie E B McArdle; Amanda K Miles; Ioannis Missitzis; Vinaya M Phatak; Des G Powe; Graham R Ball; Ian O Ellis; Angelos D Gritzapis; David C Hughes; Robert C Rees
Identification of novel breast cancer-associated transcripts by UniGene database mining and gene expression analysis in normal and malignant cells.
Ayodeji J Agboola; Ian O Ellis; R Douglas Macmillan; E Claire Paish; Des G Powe; Emad A Rakha; Andrew R Green
EpCAM expression is an indicator of recurrence in basal-like breast cancer.
Des G Powe; M J Voss; K S Zänker; Ian O Ellis; Andrew Green; H O Habashy; Frank Entschladen
Alpha- and beta-adrenergic receptor (AR) protein expression is associated with poor clinical outcome in breast cancer: an immunohistochemical study.

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All Publications

2013: Stéphanie A-S Laversin; Geng Li; Stéphanie E B McArdle; Amanda K Miles; Ioannis Missitzis; Vinaya M Phatak; Des G Powe; Graham R Ball; Ian O Ellis; Angelos D Gritzapis; David C Hughes; Robert C Rees
Identification of novel breast cancer-associated transcripts by UniGene database mining and gene expression analysis in normal and malignant cells.
Genes, chromosomes & cancer 2013;52(3):316-29.
2012: Ayodeji J Agboola; Ian O Ellis; R Douglas Macmillan; E Claire Paish; Des G Powe; Emad A Rakha; Andrew R Green
EpCAM expression is an indicator of recurrence in basal-like breast cancer.
Breast cancer research and treatment 2012;133(2):575-82.
2011: Des G Powe; M J Voss; K S Zänker; Ian O Ellis; Andrew Green; H O Habashy; Frank Entschladen
Alpha- and beta-adrenergic receptor (AR) protein expression is associated with poor clinical outcome in breast cancer: an immunohistochemical study.
Breast cancer research and treatment 2011;130(2):457-63.
2011: Hany Onsy Habashy; Emad A Rakha; Mohamed Ah Ahmed; Mohammed Aleskandarany; Ian O Ellis; Andrew R Green; Des G Powe
FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer.
Breast cancer research and treatment 2011;129(1):11-21.
2011: Hany Onsy Habashy; Natalio Krasnogor; Des G Powe; Emad A Rakha; Inmaculada Spiteri; Graham Ball; C Caldas; Jonathan M Garibaldi; Enrico Glaab; Andrew R Green; Ian O Ellis
RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype.
Breast cancer research and treatment 2011;128(2):315-26.
2011: Mohammed Aleskandarany; Emad A Rakha; R Douglas Macmillan; Des G Powe; Ian O Ellis; Andrew R Green
MIB1/Ki-67 labelling index can classify grade 2 breast cancer into two clinically distinct subgroups.
Breast cancer research and treatment 2011;127(3):591-9.
2011: Mohammed Aleskandarany; Emad A Rakha; Mohamed A Ahmed; Des G Powe; Ian O Ellis; Andrew R Green
Clinicopathologic and molecular significance of phospho-Akt expression in early invasive breast cancer.
Breast cancer research and treatment 2011;127(2):407-16.
2011: Sahar MA Mahmoud; Emma Claire Paish; Des G Powe; R Douglas Macmillan; Matthew J Grainge; Andrew H S Lee; Ian O Ellis; Andrew R Green
Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(15):1949-55.
2011: Sahar MA Mahmoud; Emma C Paish; Des G Powe; R Douglas Macmillan; Andrew H S Lee; Ian O Ellis; Andrew R Green
An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer.
Breast cancer research and treatment 2011;127(1):99-108.
2011: Abdulkader Albasri; Mohammed Aleskandarany; Ahmed Benhasouna; Des G Powe; Ian O Ellis; Mohammad Ilyas; Andrew R Green
CTEN (C-terminal tensin-like), a novel oncogene overexpressed in invasive breast carcinoma of poor prognosis.
Breast cancer research and treatment 2011;126(1):47-54.
2010: Tarek M A Abdel-Fatah; Des G Powe; Graham Ball; Maria A Lopez-Garcia; Hany O Habashy; Andrew Green; Jorge S Reis-Filho; Ian O Ellis
Proposal for a modified grading system based on mitotic index and Bcl2 provides objective determination of clinical outcome for patients with breast cancer.
The Journal of pathology 2010;222(4):388-99.
2010: Des G Powe; Melanie J Voss; Kurt S Zänker; Hany O Habashy; Andrew R Green; Ian O Ellis; Frank Entschladen
Beta-blocker drug therapy reduces secondary cancer formation in breast cancer and improves cancer specific survival.
Oncotarget 2010;1(7):628-38.
2010: Emad A Rakha; Arjun Patel; Des G Powe; Ahmed Benhasouna; Andrew Green; Maryou B K Lambros; Jorge S Reis-Filho; Ian O Ellis
Clinical and biological significance of E-cadherin protein expression in invasive lobular carcinoma of the breast.
The American journal of surgical pathology 2010;34(10):1472-9.
2010: Mohammed Aleskandarany; Emad A Rakha; Mohamed A H Ahmed; Des G Powe; Emma C Paish; R Douglas Macmillan; Ian O Ellis; Andrew Green
PIK3CA expression in invasive breast cancer: a biomarker of poor prognosis.
Breast cancer research and treatment 2010;122(1):45-53.
2010: H Zhang; Emad A Rakha; G R Ball; I Spiteri; Mohammed Aleskandarany; E C Paish; Des G Powe; R D Macmillan; C Caldas; Ian O Ellis; Andrew Green
The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer.
Breast cancer research and treatment 2010;121(1):41-51.
2010: Mohammed Aleskandarany; Andrew Green; Emad A Rakha; Rabab A Mohammed; Somaia E Elsheikh; Des G Powe; Emma C Paish; R Douglas Macmillan; Steve Chan; Samreen I Ahmed; Ian O Ellis
Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer.
International journal of cancer. Journal international du cancer 2010;126(7):1761-9.
2010: Hany Onsy Habashy; Des G Powe; Emad A Rakha; Graham Ball; R Douglas Macmillan; Andrew Green; Ian O Ellis
The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype.
Breast cancer research and treatment 2010;120(3):603-12.
2010: Tarek M Abdel-Fatah; Des G Powe; Johnson Agboola; Martyna Adamowicz-Brice; Roger W Blamey; Maria A Lopez-Garcia; Andrew Green; Jorge S Reis-Filho; Ian O Ellis
The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers.
The Journal of pathology 2010;220(4):419-34.
2010: Bina B Kulkarni; Patrick J Tighe; Imran Mohammed; Aaron M Yeung; Des G Powe; andrew Hopkinson; vijay shanmuganathan; Harminder S Dua
Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics.
BMC genomics 2010;11():526.
2010: Des G Powe; Tom Groot Kormelink; Melanie Sisson; Bart J Blokhuis; Matthias F Kramer; NS Jones; Frank A Redegeld
Evidence for the involvement of free light chain immunoglobulins in allergic and nonallergic rhinitis.
The Journal of allergy and clinical immunology 2010;125(1):139-45.e1-3.
2010: Hany Onsy Habashy; Des G Powe; Cindy M Staka; Emad A Rakha; Graham Ball; Andrew Green; Mohammed Aleskandarany; E Claire Paish; R Douglas Macmillan; Robert I Nicholson; Ian O Ellis; Julia M W Gee
Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen.
Breast cancer research and treatment 2010;119(2):283-93.
2009: Des G Powe; Amy Keightley; Mark Chester; Melanie Sisson; NS Jones
Mucosal thickening in allergic and idiopathic rhinitis mucosa and its probable mechanism.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009;103(1):14-9.
2009: Somaia E Elsheikh; Andrew Green; Emad A Rakha; Des G Powe; Rabab A Ahmed; Hilary M Collins; Daniele Soria; Jonathan M Garibaldi; Claire E Paish; Amr A Ammar; Matthew J Grainge; Graham R Ball; Magdy K Abdelghany; Luisa Martinez-Pomares; David M Heery; Ian O Ellis
Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome.
Cancer research 2009;69(9):3802-9.
2009: Des G Powe; Gulfareen Akhtar; Hany Onsy Habashy; Tarek Abdel-Fatah; Emad A Rakha; Andrew Green; Ian O Ellis
Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification.
Breast cancer research : BCR 2009;11(6):R90.
2008: Lynn Bedford; David Hay; Anny Devoy; Simon Paine; Des G Powe; Rashmi Seth; Trevor Gray; Ian Topham; Kevin Fone; Nooshin Rezvani; Maureen Mee; Tim Soane; Robert Layfield; Paul Sheppard; Ted Ebendal; Dmitry Usoskin; James Lowe; R John Mayer
Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(33):8189-98.
2008: Mohamad El-Zaatari; Anna M Grabowska; Andrew J McKenzie; Des G Powe; Paul J Scotting; Susan A Watson
Cyclopamine inhibition of the sonic hedgehog pathway in the stomach requires concomitant acid inhibition.
Regulatory peptides 2008;146(1-3):131-9.
2007: Mohamad El-Zaatari; A Tobias; Anna M Grabowska; R Kumari; Paul J Scotting; P Kaye; J Atherton; Paul A Clarke; Des G Powe; Susan A Watson
De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis.
British journal of cancer 2007;96(12):1855-61.
2007: vijay shanmuganathan; Toshana Foster; Bina B Kulkarni; andrew Hopkinson; Trevor Gray; Des G Powe; James Lowe; Harminder S Dua
Morphological characteristics of the limbal epithelial crypt.
The British journal of ophthalmology 2007;91(4):514-9.
2006: Emad A Rakha; Andrew Green; Des G Powe; Rebecca R Roylance; Ian O Ellis
Chromosome 16 tumor-suppressor genes in breast cancer.
Genes, chromosomes & cancer 2006;45(6):527-35.
2006: Emad A Rakha; Thomas C Putti; Dalia M Abd El-Rehim; Claire E Paish; Andrew Green; Des G Powe; Andrew H S Lee; John F R Robertson; Ian O Ellis
Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation.
The Journal of pathology 2006;208(4):495-506.
2004: Ibraheem El Ghrably; Des G Powe; Gavin Orr; David Fischer; Richard S McIntosh; Harminder S Dua; Patrick J Tighe
Apoptosis in proliferative vitreoretinopathy.
Investigative ophthalmology & visual science 2004;45(5):1473-9.
2000: J Clifford Murray; G Barnett; MP Tas; A Jakobsen; J Brown; Des G Powe; CA Clelland
Immunohistochemical analysis of endothelial-monocyte-activating polypeptide-II expression in vivo.
The American journal of pathology 2000;157(6):2045-53.
1998: MA Hull; Joanne Brough; Des G Powe; G I Carter; David Jenkins; Christopher J Hawkey
Expression of basic fibroblast growth factor in intact and ulcerated human gastric mucosa.
Gut 1998;43(4):525-36.
1997: Des G Powe; Joanne Brough; G I Carter; E M Bailey; William Stetler-Stevenson; D R Turner; RE Hewitt
TIMP-3 mRNA expression is regionally increased in moderately and poorly differentiated colorectal adenocarcinoma.
British journal of cancer 1997;75(11):1678-83.
1997: S Dunstan; Des G Powe; M Wilkinson; J Pearson; RE Hewitt
The tumour stroma of oral squamous cell carcinomas show increased vascularity compared with adjacent host tissue.
British journal of cancer 1997;75(4):559-65.
1997: RE Hewitt; Des G Powe; K Morrell; E Balley; I H Leach; Ian O Ellis; D R Turner
Laminin and collagen IV subunit distribution in normal and neoplastic tissues of colorectum and breast.
British journal of cancer 1997;75(2):221-9.
1996: R E Hewitt; V Linton; Des G Powe; W Sam; A Stevens; D R Turner
Morphometric evidence that epithelial basement membrane breaks are a feature of both squamous and basal cell carcinomas of the skin.
International journal of cancer. Journal international du cancer 1996;66(1):24-8.
1995: A J Pritchard; T Chatterjee; M Wilkinson; Des G Powe; T Gray; R E Hewitt
Evidence for a weak angiogenic response to human colorectal cancers.
British journal of cancer 1995;71(5):1081-6.
1995: K Tan; Des G Powe; T Gray; D R Turner; R E Hewitt
Regional variations of urokinase-type plasminogen activator in human colorectal cancer: a quantitative study by image analysis.
International journal of cancer. Journal international du cancer 1995;60(3):308-14.
1994: R E Hewitt; W Keeble; Des G Powe; R J Williamson; D R Turner
The influence of local tissue environment on epithelial basement membrane continuity in colorectal carcinomas.
International journal of cancer. Journal international du cancer 1994;56(5):675-80.
1993: R E Hewitt; Des G Powe; G Ian Carter; D R Turner
Desmoplasia and its relevance to colorectal tumour invasion.
International journal of cancer. Journal international du cancer 1993;53(1):62-9.
1992: R E Hewitt; Des G Powe; G Ian Carter; D R Turner; J E Price
Basement membrane collagen-IV synthesis in colorectal tumours.
International journal of cancer. Journal international du cancer 1992;51(4):530-6.
1992: R E Hewitt; Des G Powe; C M Holland; T Gray; D R Turner
Apparent fusion of basement membranes in colorectal carcinoma.
International journal of cancer. Journal international du cancer 1992;50(1):20-5.
1991: R E Hewitt; I H Leach; Des G Powe; Ian Clark; T E Cawston; D R Turner
Distribution of collagenase and tissue inhibitor of metalloproteinases (TIMP) in colorectal tumours.
International journal of cancer. Journal international du cancer 1991;49(5):666-72.
1991: R E Hewitt; Des G Powe; N R Griffin; D R Turner
Relationships between epithelial basement membrane staining patterns in primary colorectal carcinomas and the extent of tumour spread.
International journal of cancer. Journal international du cancer 1991;48(6):855-60.
1989: J Lowe; K A MacLennan; Des G Powe; J D Pound; J B Palmer
Microglial cells in human brain have phenotypic characteristics related to possible function as dendritic antigen presenting cells.
The Journal of pathology 1989;159(2):143-9.