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Charles Powell

Research Profile

Disorders

Activities & Behaviors

Smoking

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Oligonucleotide Array Sequence Analysis

Physiology

Gene Expression Regulation, Neoplastic

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Publications

TOP 3
Alain C Borczuk; Jinli Chen; Richard A Friedman; Ping Lu; Marieta Sole; May-Lin Wilgus; Steven M Albelda; Charles A Powell
Progression of human bronchioloalveolar carcinoma to invasive adenocarcinoma is modeled in a transgenic mouse model of K-ras-induced lung cancer by loss of the TGF-β type II receptor.
May-Lin Wilgus; Alain C Borczuk; Mark Stoopler; Mark E Ginsburg; Lyall A Gorenstein; Joshua R Sonett; Charles A Powell
Lysyl oxidase: a lung adenocarcinoma biomarker of invasion and survival.
Rebecca L Toonkel; Alain C Borczuk; Charles A Powell
Tgf-beta signaling pathway in lung adenocarcinoma invasion.

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All Publications

2011: Alain C Borczuk; Jinli Chen; Richard A Friedman; Ping Lu; Marieta Sole; May-Lin Wilgus; Steven M Albelda; Charles A Powell
Progression of human bronchioloalveolar carcinoma to invasive adenocarcinoma is modeled in a transgenic mouse model of K-ras-induced lung cancer by loss of the TGF-β type II receptor.
Cancer research 2011;71(21):6665-75.
2011: May-Lin Wilgus; Alain C Borczuk; Mark Stoopler; Mark E Ginsburg; Lyall A Gorenstein; Joshua R Sonett; Charles A Powell
Lysyl oxidase: a lung adenocarcinoma biomarker of invasion and survival.
Cancer 2011;117(10):2186-91.
2010: Rebecca L Toonkel; Alain C Borczuk; Charles A Powell
Tgf-beta signaling pathway in lung adenocarcinoma invasion.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(2):153-7.
2009: Charles A Powell
Rounding up apoptosis resistance targets in lung cancer.
American journal of respiratory cell and molecular biology 2009;41(1):7-8.
2009: Sarita Dubey; Charles A Powell
Update in lung cancer 2008.
American journal of respiratory and critical care medicine 2009;179(10):860-8.
2009: Alain C Borczuk; Rebecca L Toonkel; Charles A Powell
Genomics of lung cancer.
Proceedings of the American Thoracic Society 2009;6(2):152-8.
2009: Alain C Borczuk; Fang Qian; Angeliki Kazeros; Jennifer Eleazar; Adel Assaad; Joshua R Sonett; Mark Ginsburg; Lyall Gorenstein; Charles A Powell
Invasive size is an independent predictor of survival in pulmonary adenocarcinoma.
The American journal of surgical pathology 2009;33(3):462-9.
2008: John H M Austin; Amol Mujoomdar; Charles A Powell; Gregory D N Pearson; Harry Raftopoulos
Carcinoma of the lung and metastatic disease of the central nervous system.
American journal of respiratory and critical care medicine 2008;178(10):1090; author reply 1090.
2008: Sonia Mesia-Vela; Chih-Ching Yeh; John H M Austin; Matthew Dounel; Charles A Powell; Anthony Reeves; Regina M Santella; Lori Stevenson; David Yankelevitz; R Graham Barr
Plasma carbonyls do not correlate with lung function or computed tomography measures of lung density in older smokers.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008;13(4):422-34.
2008: Sarita Dubey; Charles A Powell
Update in lung cancer 2007.
American journal of respiratory and critical care medicine 2008;177(9):941-6.
2008: Charles A Powell
Waiting to exhale.
American journal of respiratory and critical care medicine 2008;177(3):246-7.
2008: Chih-Ching Yeh; Charles A Powell; Sonia Mesia-Vela; Yuanjia Wang; Nada K Hamade; John H M Austin; R Graham Barr; Regina M Santella
No effect of cigarette smoking dose on oxidized plasma proteins.
Environmental research 2008;106(2):219-25.
2008: Alain C Borczuk; N Papanikolaou; R L Toonkel; M Sole; Lyall A Gorenstein; Mark E Ginsburg; Joshua R Sonett; Richard A Friedman; Charles A Powell
Lung adenocarcinoma invasion in TGFbetaRII-deficient cells is mediated by CCL5/RANTES.
Oncogene 2008;27(4):557-64.
2007: Rona Yaeger; Patricia C Nolan; Tao Su; Alexa Avila-Bront; Xiaomei Wang; Ying Kuen K Cheung; Hui Liu; Vibhav S Rangarajan; Hanina Hibshoosh; Charles A Powell; Andrew K Joe
17HSD 2 may be higher in African-American breast cancer and is associated with estrogen receptor-negative tumors.
Cancer genomics & proteomics 2007;4(5):341-8.
2007: Anil Vachani; Michael Nebozhyn; shashank singhal; Linda Alila; Elliot Wakeam; Ruth J Muschel; Charles A Powell; Patrick Gaffney; Bhuvanesh Singh; Marcia S Brose; Leslie A Litzky; John C Kucharczuk; Larry R Kaiser; J Stephen Marron; Michael K Showe; Steven M Albelda; Louise C Showe
A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(10):2905-15.
2007: Sarita Dubey; Charles A Powell
Update in lung cancer 2006.
American journal of respiratory and critical care medicine 2007;175(9):868-74.
2007: Amol Mujoomdar; John H M Austin; Rohin Malhotra; Charles A Powell; Gregory D N Pearson; Maria C Shiau; Haralambos Raftopoulos
Clinical predictors of metastatic disease to the brain from non-small cell lung carcinoma: primary tumor size, cell type, and lymph node metastases.
Radiology 2007;242(3):882-8.
2007: Alain C Borczuk; G C A Cappellini; H K Kim; Mary Hesdorffer; Robert N Taub; Charles A Powell
Molecular profiling of malignant peritoneal mesothelioma identifies the ubiquitin-proteasome pathway as a therapeutic target in poor prognosis tumors.
Oncogene 2007;26(4):610-7.
2007: Benjamin Bruce; Gaurav Khanna; Ling Ren; Göran Landberg; Karin Jirström; Charles A Powell; Alain C Borczuk; Evan T Keller; Kirk J Wojno; Paul Meltzer; Kristin Baird; Andrea I McClatchey; Anthony Bretscher; Stephen M Hewitt; Chand Khanna
Expression of the cytoskeleton linker protein ezrin in human cancers.
Clinical & experimental metastasis 2007;24(2):69-78.
2007: Alain C Borczuk; Charles A Powell
Expression profiling and lung cancer development.
Proceedings of the American Thoracic Society 2007;4(1):127-32.
2006: Genze Shao; Jessica Berenguer; Alain C Borczuk; Charles A Powell; Tom K Hei; Yongliang Zhao
Epigenetic inactivation of Betaig-h3 gene in human cancer cells.
Cancer research 2006;66(9):4566-73.
2005: Alain C Borczuk; Han K Kim; Hilary A Yegen; Richard A Friedman; Charles A Powell
Lung adenocarcinoma global profiling identifies type II transforming growth factor-beta receptor as a repressor of invasiveness.
American journal of respiratory and critical care medicine 2005;172(6):729-37.
2005: Anjali Saqi; Shine S Yun; Gordon H Yu; Diane Alexis; Robert N Taub; Charles A Powell; Alain C Borczuk
Utility of CD138 (syndecan-1) in distinguishing carcinomas from mesotheliomas.
Diagnostic cytopathology 2005;33(2):65-70.
2005: Robert F Foronjy; Becky A Mercer; Mark W Maxfield; Charles A Powell; Jeanine D'Armiento; Yasunori Okada
Structural emphysema does not correlate with lung compliance: lessons from the mouse smoking model.
Experimental lung research 2005;31(6):547-62.
2005: Alain C Borczuk; Robert N Taub; Mary Hesdorffer; Hanina Hibshoosh; John A Chabot; Mary-Louise Keohan; Ritchie Alsberry; Diane Alexis; Charles A Powell
P16 loss and mitotic activity predict poor survival in patients with peritoneal malignant mesothelioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(9):3303-8.
2005: Robert M Mazziotta; Alain C Borczuk; Charles A Powell; Mahesh Mansukhani
CDX2 immunostaining as a gastrointestinal marker: expression in lung carcinomas is a potential pitfall.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2005;13(1):55-60.
2004: Lori Shah; Kristin L Walter; Alain C Borczuk; Steven M Kawut; Joshua R Sonett; Lyall A Gorenstein; Mark E Ginsburg; Kenneth M Steinglass; Charles A Powell
Expression of syndecan-1 and expression of epidermal growth factor receptor are associated with survival in patients with nonsmall cell lung carcinoma.
Cancer 2004;101(7):1632-8.
2004: Alain C Borczuk; Lori Shah; Gregory D N Pearson; Kristin L Walter; Liqun Wang; John H M Austin; Richard A Friedman; Charles A Powell
Molecular signatures in biopsy specimens of lung cancer.
American journal of respiratory and critical care medicine 2004;170(2):167-74.
2004: Alain C Borczuk; Adel M Assaad; Liqun Q Wang; Kristin L Walter; Charles A Powell
Non-small cell lung cancer molecular profiles are associated with lung development.
Chest 2004;125(5 Suppl):115S-6S.
2004: Kristin L Walter; Alain C Borczuk; Ligun Q Wang; Adel M Assaad; John H M Austin; Gregory D N Pearson; Maria C Shiau; Charles A Powell
Class prediction of lung nodule gene expression profiles.
Chest 2004;125(5 Suppl):104S.
2003: Han Kim; Guo-Liang Xu; Alain C Borczuk; Steve Busch; Jorge Filmus; Mariana Capurro; Jerome S Brody; Jennifer Lange; Jeanine D'Armiento; Paul B Rothman; Charles A Powell
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.
American journal of respiratory cell and molecular biology 2003;29(6):694-701.
2003: Alain C Borczuk; Lyall A Gorenstein; Kristin L Walter; Adel A Assaad; Liqun Wang; Charles A Powell
Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways.
The American journal of pathology 2003;163(5):1949-60.
2003: Charles A Powell; Avrum Spira; Adnan Derti; Charles DeLisi; Gang Liu; Alain C Borczuk; Steve Busch; Sudhir Sahasrabudhe; Yangde Chen; David J Sugarbaker; Raphael Bueno; William G Richards; Jerome S Brody
Gene expression in lung adenocarcinomas of smokers and nonsmokers.
American journal of respiratory cell and molecular biology 2003;29(2):157-62.
2003: Charles A Powell; Raphael Bueno; Alain C Borczuk; Cynthia F Caracta; William G Richards; David J Sugarbaker; Jerome S Brody
Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokers.
Lung cancer (Amsterdam, Netherlands) 2003;39(1):23-9.
2002: Chi-Ming Li; Meirong Guo; Alain C Borczuk; Charles A Powell; Michelle Wei; Harshwardhan M Thaker; Richard Friedman; Ulf Klein; Benjamin Tycko
Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition.
The American journal of pathology 2002;160(6):2181-90.
2002: Charles A Powell; Guoliang Xu; Jorge Filmus; Steve Busch; Jerome S Brody; Paul B Rothman
Oligonucleotide microarray analysis of lung adenocarcinoma in smokers and nonsmokers identifies GPC3 as a potential lung tumor suppressor.
Chest 2002;121(3 Suppl):6S-7S.
1999: Charles A Powell; S Klares; Gregory O'Connor; Jerome S Brody
Loss of heterozygosity in epithelial cells obtained by bronchial brushing: clinical utility in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(8):2025-34.