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Julia Prado

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Henrik N Kløverpris; Rebecca P Payne; Fabian Chen; Philip Goulder; Jane T Rasaiyaah; Jonah B Sacha; Masafumi Takiguchi; Greg J Towers; Otto O Yang; Julia G Prado
Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells.
Maria C Puertas; Peter Van Den Eede; Julia G Prado; Mònica Ballestero; Maria J Buzón; Bonaventura Clotet; Javier Martinez-Picado
Novel two-round phenotypic assay for protease inhibitor susceptibility testing of recombinant and primary HIV-1 isolates.
Maria T Rodriguez-Plata; Alejandra Urrutia; Arnaud Moris; Julia G Prado; Maria Carmen Puertas; Maria J Buzón; Sylvain Cardinaud; Samandhy Cedeño; Bonaventura Clotet; Pierre-Grégoire Coulon; Itziar Erkizia; Nuria Izquierdo-Useros; Javier Martinez-Picado
HIV-1 capture and antigen presentation by dendritic cells: enhanced viral capture does not correlate with better T cell activation.

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All Publications

2013: Henrik N Kløverpris; Rebecca P Payne; Fabian Chen; Philip Goulder; Jane T Rasaiyaah; Jonah B Sacha; Masafumi Takiguchi; Greg J Towers; Otto O Yang; Julia G Prado
Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells.
Journal of virology 2013;87(5):2628-38.
2012: Maria C Puertas; Peter Van Den Eede; Julia G Prado; Mònica Ballestero; Maria J Buzón; Bonaventura Clotet; Javier Martinez-Picado
Novel two-round phenotypic assay for protease inhibitor susceptibility testing of recombinant and primary HIV-1 isolates.
Journal of clinical microbiology 2012;50(12):3909-16.
2012: Maria T Rodriguez-Plata; Alejandra Urrutia; Arnaud Moris; Julia G Prado; Maria Carmen Puertas; Maria J Buzón; Sylvain Cardinaud; Samandhy Cedeño; Bonaventura Clotet; Pierre-Grégoire Coulon; Itziar Erkizia; Nuria Izquierdo-Useros; Javier Martinez-Picado
HIV-1 capture and antigen presentation by dendritic cells: enhanced viral capture does not correlate with better T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(12):6036-45.
2012: Nuria Izquierdo-Useros; Hans-Georg Kräusslich; Maier Lorizate; Josefina Casas; F-Xabier Contreras; Itziar Erkizia; Gemma Fabriàs; Bärbel Glass; Julia G Prado; Maria T Rodriguez-Plata; Javier Martinez-Picado
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1.
PLoS biology 2012;10(4):e1001315.
2012: Judith Dalmau; Itziar Erkizia; Javier Martinez-Picado; Roger Paredes; Maria Pino; Christian Pou; Bonaventura Clotet; Francisco M Codoñer; Julia G Prado
In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.
PloS one 2012;7(2):e32714.
2010: Isobella Honeyborne; Francisco M Codoñer; Alasdair Leslie; Gareth Tudor-Williams; Graz Luzzi; Thumbi Ndung'u; Bruce D Walker; Philip J R Goulder; Julia G Prado
HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation.
Journal of virology 2010;84(21):11279-88.
2010: Rebecca P Payne; Henrik Kløverpris; Jonah B Sacha; Zabrina Brumme; Chanson Brumme; Søren Buus; Stuart Sims; Stephen Hickling; Lynn Riddell; Fabian Chen; Graz Luzzi; Anne Edwards; Rodney Phillips; Julia G Prado; Philip J R Goulder
Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B 2705-restricted CD8+ T cells.
Journal of virology 2010;84(20):10543-57.
2010: Andrew Prendergast; Julia G Prado; Yu-Hoi Kang; Fabian Chen; Lynn A Riddell; Graz Luzzi; Philip Goulder; Paul Klenerman
HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells.
AIDS (London, England) 2010;24(4):491-502.
2010: Julia G Prado; Andrew Prendergast; Christina Thobakgale; Claudia Molina; Gareth Tudor-Williams; Thumbi Ndung'u; Bruce D Walker; Philip J R Goulder
Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rate.
Journal of virology 2010;84(1):492-502.
2009: Christina Thobakgale; Andrew Prendergast; Hayley Crawford; Nompumelelo Mkhwanazi; Danni Ramduth; Sharon Reddy; Claudia Molina; Zenele Mncube; Alasdair Leslie; Julia G Prado; Fundi Chonco; Wendy Mphatshwe; Gareth Tudor-Williams; Prakash Jeena; Natasha Blanckenberg; Krista Dong; Photini Kiepiela; Hoosen Coovadia; Thumbi Ndung'u; Bruce D Walker; Philip J R Goulder
Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection.
Journal of virology 2009;83(19):10234-44.
2009: Hayley Crawford; Wendy Lumm; Alasdair Leslie; Malinda Schaefer; Debrah Boeras; Julia G Prado; Jianming Tang; Paul Farmer; Thumbi Ndung'u; Shabir Lakhi; Jill Gilmour; Paul A Goepfert; Bruce D Walker; Richard A Kaslow; Joseph Mulenga; Susan Allen; Philip J R Goulder; Eric Hunter
Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients.
The Journal of experimental medicine 2009;206(4):909-21.
2009: Rebecca P Payne; Philippa C Matthews; Julia G Prado; Philip J R Goulder
HLA-mediated control of HIV and HIV adaptation to HLA.
Advances in parasitology 2009;68():1-20.
2009: Julia G Prado; Isobella Honeyborne; Ian Brierley; Maria Carmen Puertas; Javier Martinez-Picado; Philip J R Goulder
Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein.
Journal of virology 2009;83(2):1018-25.
2007: Hayley Crawford; Julia G Prado; Alasdair Leslie; Stéphane Hué; Isobella Honeyborne; Sharon Reddy; Mary van der Stok; Zenele Mncube; Christian Brander; Christine M Rousseau; James I Mullins; Richard A Kaslow; Paul A Goepfert; Susan Allen; Eric Hunter; Joseph Mulenga; Photini Kiepiela; Bruce D Walker; Philip J R Goulder
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.
Journal of virology 2007;81(15):8346-51.
2007: Cristina Villena; Julia G Prado; Maria Carmen Puertas; Miguel Angel Martínez; Bonaventura Clotet; Lidia Ruiz; Neil Parkin; Luis Menéndez-Arias; Javier Martinez-Picado
Relative fitness and replication capacity of a multinucleoside analogue-resistant clinical human immunodeficiency virus type 1 isolate with a deletion of codon 69 in the reverse transcriptase coding region.
Journal of virology 2007;81(9):4713-21.
2007: Photini Kiepiela; Kholiswa Ngumbela; Christina Thobakgale; Danni Ramduth; Isobella Honeyborne; Eshia Moodley; Sharon Reddy; Chantal de Pierres; Zenele Mncube; Nompumelelo Mkhwanazi; Karen Bishop; Mary van der Stok; Kriebashnie Nair; Nasreen Khan; Hayley Crawford; Rebecca Payne; Alasdair Leslie; Julia G Prado; Andrew Prendergast; John Frater; Noel McCarthy; Christian Brander; Gerald Learn; David C Nickle; Christine M Rousseau; Hoosen Coovadia; James I Mullins; David Heckerman; Bruce D Walker; Philip J R Goulder
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.
Nature medicine 2007;13(1):46-53.
2006: Javier Martinez-Picado; Julia G Prado; Elizabeth E Fry; Katja Pfafferott; Alasdair Leslie; Senica Chetty; Christina Thobakgale; Isobella Honeyborne; Hayley Crawford; Philippa Matthews; Tilly Pillay; Christine M Rousseau; James I Mullins; Christian Brander; Bruce D Walker; David I Stuart; Photini Kiepiela; Philip J R Goulder
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1.
Journal of virology 2006;80(7):3617-23.
2005: Julia G Prado; Neil Parkin; Bonaventura Clotet; Lidia Ruiz; Javier Martinez-Picado
HIV type 1 fitness evolution in antiretroviral-experienced patients with sustained CD4+ T cell counts but persistent virologic failure.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41(5):729-37.
2004: Julia G Prado; Sandra Franco; Tania Matamoros; Lidia Ruiz; Bonaventura Clotet; Luis Menéndez-Arias; Miguel Angel Martínez; Javier Martinez-Picado
Relative replication fitness of multi-nucleoside analogue-resistant HIV-1 strains bearing a dipeptide insertion in the fingers subdomain of the reverse transcriptase and mutations at codons 67 and 215.
Virology 2004;326(1):103-12.
2004: Rika Draenert; Sylvie Le Gall; Katja Pfafferott; Alasdair Leslie; Polan Chetty; Christian Brander; Edward C Holmes; Shih-Chung Chang; Margaret E Feeney; Marylyn M Addo; Lidia Ruiz; Danni Ramduth; Prakash Jeena; Marcus Altfeld; Stephanie Thomas; Yanhua Tang; Cori L Verrill; Catherine Dixon; Julia G Prado; Photini Kiepiela; Javier Martinez-Picado; Bruce D Walker; Philip J R Goulder
Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.
The Journal of experimental medicine 2004;199(7):905-15.
2004: Julia G Prado; Ayumi Shintani; Margarita Bofill; Bonaventura Clotet; Lidia Ruiz; Javier Martinez-Picado
Lack of longitudinal intrapatient correlation between p24 antigenemia and levels of human immunodeficiency virus (HIV) type 1 RNA in patients with chronic hiv infection during structured treatment interruptions.
Journal of clinical microbiology 2004;42(4):1620-5.
2004: Alasdair Leslie; Katja Pfafferott; Polan Chetty; Rika Draenert; Marylyn M Addo; Margaret E Feeney; Yanhua Tang; Edward C Holmes; Todd Allen; Julia G Prado; Marcus Altfeld; Christian Brander; C Dixon; Danni Ramduth; Prakash Jeena; S A Thomas; A St John; Timothy Roach; B Kupfer; Graz Luzzi; Anne Edwards; G Taylor; Hermione Lyall; Gareth Tudor-Williams; Vas Novelli; Javier Martinez-Picado; Photini Kiepiela; Bruce D Walker; Philip J R Goulder
HIV evolution: CTL escape mutation and reversion after transmission.
Nature medicine 2004;10(3):282-9.
2002: Julia G Prado; Terri Wrin; Jeff Beauchaine; Lidia Ruiz; Christos J Petropoulos; Simon D W Frost; Bonaventura Clotet; Richard T D'Aquila; Javier Martinez-Picado
Amprenavir-resistant HIV-1 exhibits lopinavir cross-resistance and reduced replication capacity.
AIDS (London, England) 2002;16(7):1009-17.
2002: Javier Martinez-Picado; Kristina Morales-Lopetegi; Terri Wrin; Julia G Prado; Simon D W Frost; Christos J Petropoulos; Bonaventura Clotet; Lidia Ruiz
Selection of drug-resistant HIV-1 mutants in response to repeated structured treatment interruptions.
AIDS (London, England) 2002;16(6):895-9.