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Jay Berzofsky

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
46
Belyakov, Igor
30
Ahlers, Jeffrey
29
Pendleton, David
28
Terabe, Masaki
21
Shearer, Gene
17
Clerici, Mario
15
Shirai, Mutsunori
15
Moss, Bernard
15
Margulies, David
14
Good, Michael
13
Miller, Louis
12
Oh, SangKon
11
Feinstone, Stephen
11
Cease, Kemp
9
Pinto, Ligia

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Publications

TOP 3
Terabe Masaki; Ambrosino Elena; Takaku Shun; O'Konek Jessica J; Venzon David; Lonning Scott; McPherson John M; Berzofsky Jay A
Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody.
Isakov D; Dzutsev A; Belyakov I M; Berzofsky J A
Non-equilibrium and differential function between intraepithelial and lamina propria virus-specific TCRalphabeta(+) CD8alphabeta(+) T cells in the small intestinal mucosa.
Berzofsky Jay A; Terabe Masaki
The contrasting roles of NKT cells in tumor immunity.

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All Publications

2009: Terabe Masaki; Ambrosino Elena; Takaku Shun; O'Konek Jessica J; Venzon David; Lonning Scott; McPherson John M; Berzofsky Jay A
Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(21):6560-9.
2009: Isakov D; Dzutsev A; Belyakov I M; Berzofsky J A
Non-equilibrium and differential function between intraepithelial and lamina propria virus-specific TCRalphabeta(+) CD8alphabeta(+) T cells in the small intestinal mucosa.
Mucosal immunology 2009;2(5):450-61.
2009: Berzofsky Jay A; Terabe Masaki
The contrasting roles of NKT cells in tumor immunity.
Current molecular medicine 2009;9(6):667-72.
2009: Oakley Miranda S; Majam Victoria; Mahajan Babita; Gerald Noel; Anantharaman Vivek; Ward Jerrold M; Faucette Lawrence J; McCutchan Thomas F; Zheng Hong; Terabe Masaki; Berzofsky Jay A; Aravind L; Kumar Sanjai
Pathogenic roles of CD14, galectin-3, and OX40 during experimental cerebral malaria in mice.
PloS one 2009;4(8):e6793.
2008: Wu Zheng; Xue Hai-Hui; Bernard Jérôme; Zeng Rong; Issakov Dmitry; Bollenbacher-Reilley Julie; Belyakov Igor M; Oh Sangkon; Berzofsky Jay A; Leonard Warren J
The IL-15 receptor {alpha} chain cytoplasmic domain is critical for normal IL-15Ralpha function but is not required for trans-presentation.
Blood 2008;112(12):4411-9.
2008: Belyakov Igor M; Ahlers Jeffrey D; Nabel Gary J; Moss Bernard; Berzofsky Jay A
Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization.
Virology 2008;381(1):106-15.
2008: Berzofsky Jay A; Terabe Masaki
A novel immunoregulatory axis of NKT cell subsets regulating tumor immunity.
Cancer immunology, immunotherapy : CII 2008;57(11):1679-83.
2008: Zhu Qing; Egelston Colt; Vivekanandhan Aravindhan; Uematsu Satoshi; Akira Shizuo; Klinman Dennis M; Belyakov Igor M; Berzofsky Jay A
Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16260-5.
2008: Hall Jason A; Bouladoux Nicolas; Sun Cheng Ming; Wohlfert Elizabeth A; Blank Rebecca B; Zhu Qing; Grigg Michael E; Berzofsky Jay A; Belkaid Yasmine
Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses.
Immunity 2008;29(4):637-49.
2008: Mackall Crystal L; Rhee Eunice H; Read Elizabeth J; Khuu Hanh M; Leitman Susan F; Bernstein Donna; Tesso Merertu; Long Lauren M; Grindler David; Merino Margret; Kopp William; Tsokos Maria; Berzofsky Jay A; Helman Lee J
A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4850-8.
2008: Terabe Masaki; Tagaya Yutaka; Zhu Qing; Granger Larry; Roederer Mario; Waldmann Thomas A; Berzofsky Jay A
IL-15 expands unconventional CD8alphaalphaNK1.1+ T cells but not Valpha14Jalpha18+ NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7276-86.
2008: Ambrosino Elena; Berzofsky Jay A; Terabe Masaki
Regulation of tumor immunity: the role of NKT cells.
Expert opinion on biological therapy 2008;8(6):725-34.
2008: Park Jong Myun; Terabe Masaki; Donaldson Debra D; Forni Guido; Berzofsky Jay A
Natural immunosurveillance against spontaneous, autochthonous breast cancers revealed and enhanced by blockade of IL-13-mediated negative regulation.
Cancer immunology, immunotherapy : CII 2008;57(6):907-12.
2008: Nam Jeong-Seok; Terabe Masaki; Kang Mi-Jin; Chae Helen; Voong Nga; Yang Yu-An; Laurence Arian; Michalowska Aleksandra; Mamura Mizuko; Lonning Scott; Berzofsky Jay A; Wakefield Lalage M
Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17.
Cancer research 2008;68(10):3915-23.
2008: Nam Jeong-Seok; Terabe Masaki; Mamura Mizuko; Kang Mi-Jin; Chae Helen; Stuelten Christina; Kohn Ethan; Tang Binwu; Sabzevari Helen; Anver Miriam R; Lawrence Scott; Danielpour David; Lonning Scott; Berzofsky Jay A; Wakefield Lalage M
An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.
Cancer research 2008;68(10):3835-43.
2008: Fichtner-Feigl Stefan; Terabe Masaki; Kitani Atsushi; Young Cheryl A; Fuss Ivan; Geissler Edward K; Schlitt Hans-Jürgen; Berzofsky Jay A; Strober Warren
Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2.
Cancer research 2008;68(9):3467-75.
2008: Oh Sangkon; Perera Liyanage P; Terabe Masaki; Ni Ling; Waldmann Thomas A; Berzofsky Jay A
IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(13):5201-6.
2008: Dzutsev Amiran K; Belyakov Igor M; Isakov Dmitry V; Gagnon Susan J; Margulies David H; Berzofsky Jay A
Estimation of low frequency antigen-presenting cells with a novel RELISPOT assay.
Journal of immunological methods 2008;333(1-2):71-8.
2008: Park Jong Myun; Terabe Masaki; Steel Jason C; Forni Guido; Sakai Yoshio; Morris John C; Berzofsky Jay A
Therapy of advanced established murine breast cancer with a recombinant adenoviral ErbB-2/neu vaccine.
Cancer research 2008;68(6):1979-87.
2008: Berzofsky Jay A; Terabe Masaki
NKT cells in tumor immunity: opposing subsets define a new immunoregulatory axis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(6):3627-35.
2008: Wyatt Linda S; Belyakov Igor M; Earl Patricia L; Berzofsky Jay A; Moss Bernard
Enhanced cell surface expression, immunogenicity and genetic stability resulting from a spontaneous truncation of HIV Env expressed by a recombinant MVA.
Virology 2008;372(2):260-72.
2008: Terabe Masaki; Berzofsky Jay A
The role of NKT cells in tumor immunity.
Advances in cancer research 2008;101():277-348.
2007: Belyakov Igor M; Kozlowski Steven; Mage Michael; Ahlers Jeffrey D; Boyd Lisa F; Margulies David H; Berzofsky Jay A
Role of alpha3 domain of class I MHC molecules in the activation of high- and low-avidity CD8+ CTLs.
International immunology 2007;19(12):1413-20.
2007: Terabe Masaki; Berzofsky Jay A
NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis.
Trends in immunology 2007;28(11):491-6.
2007: Ambrosino Elena; Terabe Masaki; Halder Ramesh C; Peng Judy; Takaku Shun; Miyake Sachiko; Yamamura Takashi; Kumar Vipin; Berzofsky Jay A
Cross-regulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5126-36.
2007: Toubaji Antoun; Hill Sarah; Terabe Masaki; Qian Jiahua; Floyd Tamara; Simpson R Mark; Berzofsky Jay A; Khleif Samir N
The combination of GM-CSF and IL-2 as local adjuvant shows synergy in enhancing peptide vaccines and provides long term tumor protection.
Vaccine 2007;25(31):5882-91.
2007: Perera Liyanage P; Waldmann Thomas A; Mosca Joseph D; Baldwin Nicole; Berzofsky Jay A; Oh Sang-Kon
Development of smallpox vaccine candidates with integrated interleukin-15 that demonstrate superior immunogenicity, efficacy, and safety in mice.
Journal of virology 2007;81(16):8774-83.
2007: Belyakov Igor M; Isakov Dmitry; Zhu Qing; Dzutsev Amiran; Berzofsky Jay A
A novel functional CTL avidity/activity compartmentalization to the site of mucosal immunization contributes to protection of macaques against simian/human immunodeficiency viral depletion of mucosal CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7211-21.
2007: Ota Martin O; Ndhlovu Zaza; Oh SangKon; Piyasirisilp Sucheep; Berzofsky Jay A; Moss William J; Griffin Diane E
Hemagglutinin protein is a primary target of the measles virus-specific HLA-A2-restricted CD8+ T cell response during measles and after vaccination.
The Journal of infectious diseases 2007;195(12):1799-807.
2007: Dzutsev Amiran H; Belyakov Igor M; Isakov Dmitry V; Margulies David H; Berzofsky Jay A
Avidity of CD8 T cells sharpens immunodominance.
International immunology 2007;19(4):497-507.
2006: García-Piñeres Alfonso J; Hildesheim Allan; Herrero Rolando; Trivett Matthew; Williams Marcus; Atmetlla Ivannia; Ramírez Margarita; Villegas Maricela; Schiffman Mark; Rodríguez Ana Cecilia; Burk Robert D; Hildesheim Mariana; Freer Enrique; Bonilla José; Bratti Concepción; Berzofsky Jay A; Pinto Ligia A
Persistent human papillomavirus infection is associated with a generalized decrease in immune responsiveness in older women.
Cancer research 2006;66(22):11070-6.
2006: Belyakov Igor M; Isakov Dmitry; Zhu Qing; Dzutsev Amiran; Klinman Dennis; Berzofsky Jay A
Enhancement of CD8+ T cell immunity in the lung by CpG oligodeoxynucleotides increases protective efficacy of a modified vaccinia Ankara vaccine against lethal poxvirus infection even in a CD4-deficient host.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6336-43.
2006: Okazaki Takahiro; Terabe Masaki; Catanzaro Andrew T; Pendleton C David; Yarchoan Robert; Berzofsky Jay A
Possible therapeutic vaccine strategy against human immunodeficiency virus escape from reverse transcriptase inhibitors studied in HLA-A2 transgenic mice.
Journal of virology 2006;80(21):10645-51.
2006: Pinto Ligia A; Viscidi Raphael; Harro Clayton D; Kemp Troy J; García-Piñeres Alfonso J; Trivett Matthew; Demuth Franklin; Lowy Douglas R; Schiller John T; Berzofsky Jay A; Hildesheim Allan
Cellular immune responses to HPV-18, -31, and -53 in healthy volunteers immunized with recombinant HPV-16 L1 virus-like particles.
Virology 2006;353(2):451-62.
2006: Oh SangKon; Stegman Brian; Pendleton C David; Ota Martin O; Pan Chien-Hsiung; Griffin Diane E; Burke Donald S; Berzofsky Jay A
Protective immunity provided by HLA-A2 epitopes for fusion and hemagglutinin proteins of measles virus.
Virology 2006;352(2):390-9.
2006: Kawakami Koji; Terabe Masaki; Kioi Mitomu; Berzofsky Jay A; Puri Raj K
Intratumoral therapy with IL13-PE38 results in effective CTL-mediated suppression of IL-13Ralpha2-expressing contralateral tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4678-86.
2006: Kotelkin Alexander; Belyakov Igor M; Yang Lijuan; Berzofsky Jay A; Collins Peter L; Bukreyev Alexander
The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response.
Journal of virology 2006;80(12):5958-67.
2006: Qian Jiahua; Dong Yujun; Pang Yuk-Ying S; Ibrahim Ramy; Berzofsky Jay A; Schiller John T; Khleif Samir N
Combined prophylactic and therapeutic cancer vaccine: enhancing CTL responses to HPV16 E2 using a chimeric VLP in HLA-A2 mice.
International journal of cancer. Journal international du cancer 2006;118(12):3022-9.
2006: Kawakami Koji; Terabe Masaki; Kawakami Mariko; Berzofsky Jay A; Puri Raj K
Characterization of a novel human tumor antigen interleukin-13 receptor alpha2 chain.
Cancer research 2006;66(8):4434-42.
2006: Terabe Masaki; Khanna Chand; Bose Seuli; Melchionda Fraia; Mendoza Arnulfo; Mackall Crystal L; Helman Lee J; Berzofsky Jay A
CD1d-restricted natural killer T cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta.
Cancer research 2006;66(7):3869-75.
2006: Pal Ranajit; Venzon David; Santra Sampa; Kalyanaraman Vaniambadi S; Montefiori David C; Hocker Lindsey; Hudacik Lauren; Rose Nicolas; Nacsa Janos; Edghill-Smith Yvette; Moniuszko Marcin; Hel Zdenek; Belyakov Igor M; Berzofsky Jay A; Parks Robyn Washington; Markham Phillip D; Letvin Norman L; Tartaglia Jim; Franchini Genoveffa
Systemic immunization with an ALVAC-HIV-1/protein boost vaccine strategy protects rhesus macaques from CD4+ T-cell loss and reduces both systemic and mucosal simian-human immunodeficiency virus SHIVKU2 RNA levels.
Journal of virology 2006;80(8):3732-42.
2006: Belyakov Igor M; Kuznetsov Vladimir A; Kelsall Brian; Klinman Dennis; Moniuszko Marcin; Lemon Michael; Markham Phillip D; Pal Ranajit; Clements John D; Lewis Mark G; Strober Warren; Franchini Genoveffa; Berzofsky Jay A
Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa.
Blood 2006;107(8):3258-64.
2006: Okazaki Takahiro; Pendleton C David; Sarobe Pablo; Thomas Elaine K; Iyengar Sujatha; Harro Clayton; Schwartz David; Berzofsky Jay A
Epitope enhancement of a CD4 HIV epitope toward the development of the next generation HIV vaccine.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3753-9.
2006: van den Broeke Leon T; Pendleton C David; Mackall Crystal; Helman Lee J; Berzofsky Jay A
Identification and epitope enhancement of a PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation inducing CTL capable of lysing human tumors.
Cancer research 2006;66(3):1818-23.
2006: Dong Yujun; Qian Jiahua; Ibrahim Ramy; Berzofsky Jay A; Khleif Samir N
Identification of H-2Db-specific CD8+ T-cell epitopes from mouse VEGFR2 that can inhibit angiogenesis and tumor growth.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(1):32-40.
2005: Terabe Masaki; Swann Jeremy; Ambrosino Elena; Sinha Pratima; Takaku Shun; Hayakawa Yoshihiro; Godfrey Dale I; Ostrand-Rosenberg Suzanne; Smyth Mark J; Berzofsky Jay A
A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance.
The Journal of experimental medicine 2005;202(12):1627-33.
2005: Zhang Hua; Chua Kevin S; Guimond Martin; Kapoor Veena; Brown Margaret V; Fleisher Thomas A; Long Lauren M; Bernstein Donna; Hill Brenna J; Douek Daniel C; Berzofsky Jay A; Carter Charles S; Read E J; Helman Lee J; Mackall Crystal L
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells.
Nature medicine 2005;11(11):1238-43.
2005: Bukreyev Alexander; Belyakov Igor M; Prince Gregory A; Yim Kevin C; Harris Katie K; Berzofsky Jay A; Collins Peter L
Expression of interleukin-4 by recombinant respiratory syncytial virus is associated with accelerated inflammation and a nonfunctional cytotoxic T-lymphocyte response following primary infection but not following challenge with wild-type virus.
Journal of virology 2005;79(15):9515-26.
2005: Carbone David P; Ciernik I Frank; Kelley Michael J; Smith M Charles; Nadaf Sorena; Kavanaugh Denise; Maher V Ellen; Stipanov Michael; Contois David; Johnson Bruce E; Pendleton C David; Seifert Burkhardt; Carter Charley; Read Elizabeth J; Greenblatt Jay; Top Lois E; Kelsey Morris I; Minna John D; Berzofsky Jay A
Immunization with mutant p53- and K-ras-derived peptides in cancer patients: immune response and clinical outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(22):5099-107.
2005: Pinto Ligia A; Castle Philip E; Roden Richard B; Harro Clayton D; Lowy Douglas R; Schiller John T; Wallace Dora; Williams Marcus; Kopp William; Frazer Ian H; Berzofsky Jay A; Hildesheim Allan
HPV-16 L1 VLP vaccine elicits a broad-spectrum of cytokine responses in whole blood.
Vaccine 2005;23(27):3555-64.
2005: Park Jong Myun; Terabe Masaki; Sakai Yoshio; Munasinghe Jeeva; Forni Guido; Morris John C; Berzofsky Jay A
Early role of CD4+ Th1 cells and antibodies in HER-2 adenovirus vaccine protection against autochthonous mammary carcinomas.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4228-36.
2005: Park Jong Myun; Terabe Masaki; van den Broeke Leon T; Donaldson Debra D; Berzofsky Jay A
Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13.
International journal of cancer. Journal international du cancer 2005;114(1):80-7.
2005: Zeng Rong; Spolski Rosanne; Finkelstein Steven E; Oh SangKon; Kovanen Panu E; Hinrichs Christian S; Pise-Masison Cynthia A; Radonovich Michael F; Brady John N; Restifo Nicholas P; Berzofsky Jay A; Leonard Warren J
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.
The Journal of experimental medicine 2005;201(1):139-48.
2005: Pinto Ligia A; Trivett Matthew T; Wallace Dora; Higgins Jeanette; Baseler Michael; Terabe Masaki; Belyakov Igor M; Berzofsky Jay A; Hildesheim Allan
Fixation and cryopreservation of whole blood and isolated mononuclear cells: Influence of different procedures on lymphocyte subset analysis by flow cytometry.
Cytometry. Part B, Clinical cytometry 2005;63(1):47-55.
2005: Berzofsky Jay A; Oh Sangkon; Terabe Masaki
Peptide vaccines against cancer.
Cancer treatment and research 2005;123():115-36.
2004: Kuznetsov V A; Stepanov V S; Berzofsky J A; Belyakov I M
Assessment of the relative therapeutic effects of vaccines on virus load and immune responses in small groups at several time points: efficacy of mucosal and subcutaneous polypeptide vaccines in rhesus macaques exposed to SHIV.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;31 Suppl 1():S69-82.
2004: De Groot Anne S; Berzofsky Jay A
From genome to vaccine--new immunoinformatics tools for vaccine design.
Methods (San Diego, Calif.) 2004;34(4):425-8.
2004: Sakai Yoshio; Morrison Brian J; Burke J Douglas; Park Jong-Myun; Terabe Masaki; Janik John E; Forni Guido; Berzofsky Jay A; Morris John C
Vaccination by genetically modified dendritic cells expressing a truncated neu oncogene prevents development of breast cancer in transgenic mice.
Cancer research 2004;64(21):8022-8.
2004: Oh SangKon; Perera Liyanage P; Burke Donald S; Waldmann Thomas A; Berzofsky Jay A
IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(42):15154-9.
2004: Berzofsky Jay A; Ahlers Jeffrey D; Janik John; Morris John; Oh SangKon; Terabe Masaki; Belyakov Igor M
Progress on new vaccine strategies against chronic viral infections.
The Journal of clinical investigation 2004;114(4):450-62.
2004: Belyakov Igor M; Ahlers Jeffrey D; Berzofsky Jay A
Mucosal AIDS vaccines: current status and future directions.
Expert review of vaccines 2004;3(4 Suppl):S65-73.
2004: Lee Won Jin; Cantor Kenneth P; Berzofsky Jay A; Zahm Shelia H; Blair Aaron
Non-Hodgkin's lymphoma among asthmatics exposed to pesticides.
International journal of cancer. Journal international du cancer 2004;111(2):298-302.
2004: Snyder James T; Belyakov Igor M; Dzutsev Amiran; Lemonnier François; Berzofsky Jay A
Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses.
Journal of virology 2004;78(13):7052-60.
2004: Berzofsky Jay A; Terabe Masaki; Oh SangKon; Belyakov Igor M; Ahlers Jeffrey D; Janik John E; Morris John C
Progress on new vaccine strategies for the immunotherapy and prevention of cancer.
The Journal of clinical investigation 2004;113(11):1515-25.
2004: Oh SangKon; Terabe Masaki; Pendleton C David; Bhattacharyya Anu; Bera Tapan K; Epel Malka; Reiter Yoram; Phillips John; Linehan W Marston; Kasten-Sportes Claude; Pastan Ira; Berzofsky Jay A
Human CTLs to wild-type and enhanced epitopes of a novel prostate and breast tumor-associated protein, TARP, lyse human breast cancer cells.
Cancer research 2004;64(7):2610-8.
2004: Belyakov Igor M; Hammond Scott A; Ahlers Jeffrey D; Glenn Gregory M; Berzofsky Jay A
Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells.
The Journal of clinical investigation 2004;113(7):998-1007.
2004: Terabe Masaki; Berzofsky Jay A
Immunoregulatory T cells in tumor immunity.
Current opinion in immunology 2004;16(2):157-62.
2004: Belyakov Igor M; Berzofsky Jay A
Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines.
Immunity 2004;20(3):247-53.
2004: Terabe Masaki; Park Jong Myun; Berzofsky Jay A
Role of IL-13 in regulation of anti-tumor immunity and tumor growth.
Cancer immunology, immunotherapy : CII 2004;53(2):79-85.
2003: Terabe Masaki; Matsui So; Park Jong-Myun; Mamura Mizuko; Noben-Trauth Nancy; Donaldson Debra D; Chen Wanjun; Wahl Sharon M; Ledbetter Steven; Pratt Bruce; Letterio John J; Paul William E; Berzofsky Jay A
Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.
The Journal of experimental medicine 2003;198(11):1741-52.
2003: van den Broeke Leon T; Daschbach Emily; Thomas Elaine K; Andringa Gerda; Berzofsky Jay A
Dendritic cell-induced activation of adaptive and innate antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5842-52.
2003: Edghill-Smith Yvette; Venzon David; Karpova Tatiana; McNally James; Nacsa Janos; Tsai Wen-Po; Tryniszewska Elzbieta; Moniuszko Marcin; Manischewitz Jody; King Lisa R; Snodgrass Steven J; Parrish John; Markham Phil; Sowers Marsha; Martin Derrick; Lewis Mark G; Berzofsky Jay A; Belyakov Igor M; Moss Bernard; Tartaglia Jim; Bray Mike; Hirsch Vanessa; Golding Hana; Franchini Genoveffa
Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques.
The Journal of infectious diseases 2003;188(8):1181-91.
2003: Okazaki Takahiro; Pendleton C David; Lemonnier François; Berzofsky Jay A
Epitope-enhanced conserved HIV-1 peptide protects HLA-A2-transgenic mice against virus expressing HIV-1 antigen.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2548-55.
2003: Belyakov Igor M; Earl Patricia; Dzutsev Amiran; Kuznetsov Vladimir A; Lemon Michael; Wyatt Linda S; Snyder James T; Ahlers Jeffrey D; Franchini Genoveffa; Moss Bernard; Berzofsky Jay A
Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9458-63.
2003: Pinto Ligia A; Edwards Jessica; Castle Philip E; Harro Clayton D; Lowy Douglas R; Schiller John T; Wallace Dora; Kopp William; Adelsberger Joseph W; Baseler Michael W; Berzofsky Jay A; Hildesheim Allan
Cellular immune responses to human papillomavirus (HPV)-16 L1 in healthy volunteers immunized with recombinant HPV-16 L1 virus-like particles.
The Journal of infectious diseases 2003;188(2):327-38.
2003: Ahlers Jeffrey D; Belyakov Igor M; Berzofsky Jay A
Cytokine, chemokine, and costimulatory molecule modulation to enhance efficacy of HIV vaccines.
Current molecular medicine 2003;3(3):285-301.
2003: Oh SangKon; Berzofsky Jay A; Burke Donald S; Waldmann Thomas A; Perera Liyanage P
Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3392-7.
2003: Oh SangKon; Hodge James W; Ahlers Jeffrey D; Burke Donald S; Schlom Jeffrey; Berzofsky Jay A
Selective induction of high avidity CTL by altering the balance of signals from APC.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2523-30.
2002: Takahashi Megumi; Osono Eiichi; Nakagawa Yohko; Wang Jian; Berzofsky Jay A; Margulies David H; Takahashi Hidemi
Rapid induction of apoptosis in CD8+ HIV-1 envelope-specific murine CTLs by short exposure to antigenic peptide.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6588-93.
2002: Ostrand-Rosenberg Suzanne; Clements Virginia K; Terabe Masaki; Park Jong Myun; Berzofsky Jay A; Dissanayake Samudra K
Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-gamma dependent.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5796-804.
2002: Allen Todd M; Jing Peicheng; Calore Briana; Horton Helen; O'Connor David H; Hanke Tomas; Piekarczyk Marian; Ruddersdorf Richard; Mothé Bianca R; Emerson Carol; Wilson Nancy; Lifson Jeffrey D; Belyakov Igor M; Berzofsky Jay A; Wang Chenxi; Allison David B; Montefiori David C; Desrosiers Ronald C; Wolinsky Steven; Kunstman Kevin J; Altman John D; Sette Alessandro; McMichael Andrew J; Watkins David I
Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.
Journal of virology 2002;76(20):10507-11.
2002: Ahlers Jeffrey D; Belyakov Igor M; Terabe Masaki; Koka Rima; Donaldson Debra D; Thomas Elaine K; Berzofsky Jay A
A push-pull approach to maximize vaccine efficacy: abrogating suppression with an IL-13 inhibitor while augmenting help with granulocyte/macrophage colony-stimulating factor and CD40L.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):13020-5.
2002: Biragyn Arya; Belyakov Igor M; Chow Yen-Hung; Dimitrov Dimiter S; Berzofsky Jay A; Kwak Larry W
DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses.
Blood 2002;100(4):1153-9.
2002: Dagher Ramzi; Long Lauren M; Read Elizabeth J; Leitman Susan F; Carter Charles S; Tsokos Maria; Goletz Theresa J; Avila Nilo; Berzofsky Jay A; Helman Lee J; Mackall Crystal L
Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: an inter-institute NIH study.
Medical and pediatric oncology 2002;38(3):158-64.
2001: Berzofsky J A; Ahlers J D; Belyakov I M
Strategies for designing and optimizing new generation vaccines.
Nature reviews. Immunology 2001;1(3):209-19.
2001: Belyakov I M; Wang J; Koka R; Ahlers J D; Snyder J T; Tse R; Cox J; Gibbs J S; Margulies D H; Berzofsky J A
Activating CTL precursors to reveal CTL function without skewing the repertoire by in vitro expansion.
European journal of immunology 2001;31(12):3557-66.
2001: Ahlers J D; Belyakov I M; Thomas E K; Berzofsky J A
High-affinity T helper epitope induces complementary helper and APC polarization, increased CTL, and protection against viral infection.
The Journal of clinical investigation 2001;108(11):1677-85.
2001: Belyakov I M; Hel Z; Kelsall B; Kuznetsov V A; Ahlers J D; Nacsa J; Watkins D I; Allen T M; Sette A; Altman J; Woodward R; Markham P D; Clements J D; Franchini G; Strober W; Berzofsky J A
Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques.
Nature medicine 2001;7(12):1320-6.
2001: Bukreyev A; Belyakov I M; Berzofsky J A; Murphy B R; Collins P L
Granulocyte-macrophage colony-stimulating factor expressed by recombinant respiratory syncytial virus attenuates viral replication and increases the level of pulmonary antigen-presenting cells.
Journal of virology 2001;75(24):12128-40.
2001: Hel Z; Nacsa J; Kelsall B; Tsai W P; Letvin N; Parks R W; Tryniszewska E; Picker L; Lewis M G; Edghill-Smith Y; Moniuszko M; Pal R; Stevceva L; Altman J D; Allen T M; Watkins D; Torres J V; Berzofsky J A; Belyakov I M; Strober W; Franchini G
Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques.
Journal of virology 2001;75(23):11483-95.
2001: Marshall M A; Jankovic D; Maher V E; Sher A; Berzofsky J A
Mice infected with Schistosoma mansoni develop a novel non-T-lymphocyte suppressor population which inhibits virus-specific CTL induction via a soluble factor.
Microbes and infection / Institut Pasteur 2001;3(13):1051-61.
2001: Ahlers J D; Belyakov I M; Matsui S; Berzofsky J A
Signals delivered through TCR instruct IL-12 receptor (IL-12R) expression: IL-12 and tumor necrosis factor-alpha synergize for IL-12R expression at low antigen dose.
International immunology 2001;13(11):1433-42.
2001: Derby M A; Snyder J T; Tse R; Alexander-Miller M A; Berzofsky J A
An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL.
European journal of immunology 2001;31(10):2951-9.
2001: Worley B S; van den Broeke L T; Goletz T J; Pendleton C D; Daschbach E M; Thomas E K; Marincola F M; Helman L J; Berzofsky J A
Antigenicity of fusion proteins from sarcoma-associated chromosomal translocations.
Cancer research 2001;61(18):6868-75.
2001: Berzofsky J A
Design of engineered vaccines for systemic and mucosal immunity to HIV.
Pathologie-biologie 2001;49(6):466-7.
2001: Chung D H; Belyakov I M; Derby M A; Wang J; Boyd L F; Berzofsky J A; Margulies D H
Competitive inhibition in vivo and skewing of the T cell repertoire of antigen-specific CTL priming by an anti-peptide-MHC monoclonal antibody.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(2):699-707.
2001: Ahlers J D; Belyakov I M; Matsui S; Berzofsky J A
Mechanisms of cytokine synergy essential for vaccine protection against viral challenge.
International immunology 2001;13(7):897-908.
2001: Derby M A; Wang J; Margulies D H; Berzofsky J A
Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining.
International immunology 2001;13(6):817-24.
2001: Arichi T; Saito T; Major M E; Belyakov I M; Shirai M; Engelhard V H; Feinstone S M; Berzofsky J A
Retraction.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5943.
2001: Simon R M; Steinberg S M; Hamilton M; Hildesheim A; Khleif S; Kwak L W; Mackall C L; Schlom J; Topalian S L; Berzofsky J A
Clinical trial designs for the early clinical development of therapeutic cancer vaccines.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(6):1848-54.
2001: Shirai M; Fujinaga R; Masaki T; Berzofsky J A
Impaired development of HIV-1 gp160-specific CD8(+) cytotoxic T cells by a delayed switch from Th1 to Th2 cytokine phenotype in mice with Helicobacter pylori infection.
European journal of immunology 2001;31(2):516-26.
2001: Derby M; Alexander-Miller M; Tse R; Berzofsky J
High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1690-7.
2001: Takahashi M; Nakagawa Y; Berzofsky J A; Takahashi H
Counter-regulation of cytolytic activity and cytokine production in HIV-1-specific murine CD8+ cytotoxic T lymphocytes by free antigenic peptide.
International immunology 2001;13(1):43-51.
2001: Wong E C; Maher V E; Hines K; Lee J; Carter C S; Goletz T; Kopp W; Mackall C L; Berzofsky J; Read E J
Development of a clinical-scale method for generation of dendritic cells from PBMC for use in cancer immunotherapy.
Cytotherapy 2001;3(1):19-29.
2000: Terabe M; Matsui S; Noben-Trauth N; Chen H; Watson C; Donaldson D D; Carbone D P; Paul W E; Berzofsky J A
NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway.
Nature immunology 2000;1(6):515-20.
2000: Belyakov I M; Ahlers J D; Clements J D; Strober W; Berzofsky J A
Interplay of cytokines and adjuvants in the regulation of mucosal and systemic HIV-specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6454-62.
2000: Polakova K; Plaksin D; Chung D H; Belyakov I M; Berzofsky J A; Margulies D H
Antibodies directed against the MHC-I molecule H-2Dd complexed with an antigenic peptide: similarities to a T cell receptor with the same specificity.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5703-12.
2000: Nakagawa Y; Takeshita T; Berzofsky J A; Takahashi H
Analysis of the mechanism for extracellular processing in the presentation of human immunodeficiency virus-1 envelope protein-derived peptide to epitope-specific cytotoxic T lymphocytes.
Immunology 2000;101(1):76-82.
2000: Grene E; Newton D A; Brown E A; Berzofsky J A; Gattoni-Celli S; Shearer G M
Semi-allogeneic cell hybrids stimulate HIV-1 envelope-specific cytotoxic T lymphocytes.
AIDS (London, England) 2000;14(11):1497-506.
2000: Mackall C; Berzofsky J; Helman L J
Targeting tumor specific translocations in sarcomas in pediatric patients for immunotherapy.
Clinical orthopaedics and related research 2000;(373):25-31.
2000: Arichi T; Saito T; Major M E; Belyakov I M; Shirai M; Engelhard V H; Feinstone S M; Berzofsky J A
Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):297-302.
1999: Pinto L A; Berzofsky J A; Fowke K R; Little R F; Merced-Galindez F; Humphrey R; Ahlers J; Dunlop N; Cohen R B; Steinberg S M; Nara P; Shearer G M; Yarchoan R
HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients.
AIDS (London, England) 1999;13(15):2003-12.
1999: Chung D H; Dorfman J; Plaksin D; Natarajan K; Belyakov I M; Hunziker R; Berzofsky J A; Yokoyama W M; Mage M G; Margulies D H
NK and CTL recognition of a single chain H-2Dd molecule: distinct sites of H-2Dd interact with NK and TCR.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3699-708.
1999: Berzofsky J A; Ahlers J D; Derby M A; Pendleton C D; Arichi T; Belyakov I M
Approaches to improve engineered vaccines for human immunodeficiency virus and other viruses that cause chronic infections.
Immunological reviews 1999;170():151-72.
1999: Matsui S; Ahlers J D; Vortmeyer A O; Terabe M; Tsukui T; Carbone D P; Liotta L A; Berzofsky J A
A model for CD8+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):184-93.
1999: Belyakov I M; Moss B; Strober W; Berzofsky J A
Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(8):4512-7.
1999: McDyer J F; Dybul M; Goletz T J; Kinter A L; Thomas E K; Berzofsky J A; Fauci A S; Seder R A
Differential effects of CD40 ligand/trimer stimulation on the ability of dendritic cells to replicate and transmit HIV infection: evidence for CC-chemokine-dependent and -independent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3711-7.
1999: Shirai M; Arichi T; Chen M; Masaki T; Nishioka M; Ikeda K; Takahashi H; Enomoto N; Saito T; Major M E; Nakazawa T; Akatsuka T; Feinstone S M; Berzofsky J A
T cell recognition of hypervariable region-1 from hepatitis C virus envelope protein with multiple class II MHC molecules in mice and humans: preferential help for induction of antibodies to the hypervariable region.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(1):568-76.
1998: Belyakov I M; Ahlers J D; Brandwein B Y; Earl P; Kelsall B L; Moss B; Strober W; Berzofsky J A
The importance of local mucosal HIV-specific CD8(+) cytotoxic T lymphocytes for resistance to mucosal viral transmission in mice and enhancement of resistance by local administration of IL-12.
The Journal of clinical investigation 1998;102(12):2072-81.
1998: Leggatt G R; Hosmalin A; Pendleton C D; Kumar A; Hoffman S; Berzofsky J A
The importance of pairwise interactions between peptide residues in the delineation of TCR specificity.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4728-35.
1998: Alexander-Miller M A; Derby M A; Sarin A; Henkart P A; Berzofsky J A
Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes.
The Journal of experimental medicine 1998;188(8):1391-9.
1998: Belyakov I M; Wyatt L S; Ahlers J D; Earl P; Pendleton C D; Kelsall B L; Strober W; Moss B; Berzofsky J A
Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein.
Journal of virology 1998;72(10):8264-72.
1998: Sarobe P; Pendleton C D; Akatsuka T; Lau D; Engelhard V H; Feinstone S M; Berzofsky J A
Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions.
The Journal of clinical investigation 1998;102(6):1239-48.
1998: Tian J H; Good M F; Hirunpetcharat C; Kumar S; Ling I T; Jackson D; Cooper J; Lukszo J; Coligan J; Ahlers J; Saul A; Berzofsky J A; Holder A A; Miller L H; Kaslow D C
Definition of T cell epitopes within the 19 kDa carboxylterminal fragment of Plasmodium yoelii merozoite surface protein 1 (MSP1(19)) and their role in immunity to malaria.
Parasite immunology 1998;20(6):263-78.
1998: Belyakov I M; Derby M A; Ahlers J D; Kelsall B L; Earl P; Moss B; Strober W; Berzofsky J A
Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1709-14.
1998: Shirai M; Arichi T; Nakazawa T; Berzofsky J A
Persistent infection by Helicobacter pylori down-modulates virus-specific CD8+ cytotoxic T cell response and prolongs viral infection.
The Journal of infectious diseases 1998;177(1):72-80.
1998: Goletz T J; Mackall C L; Berzofsky J A; Helman L J
Molecular alterations in pediatric sarcomas: potential targets for immunotherapy.
Sarcoma 1998;2(2):77-87.
1997: Goletz T J; Klimpel K R; Arora N; Leppla S H; Keith J M; Berzofsky J A
Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):12059-64.
1997: Hirunpetcharat C; Tian J H; Kaslow D C; van Rooijen N; Kumar S; Berzofsky J A; Miller L H; Good M F
Complete protective immunity induced in mice by immunization with the 19-kilodalton carboxyl-terminal fragment of the merozoite surface protein-1 (MSP1[19]) of Plasmodium yoelii expressed in Saccharomyces cerevisiae: correlation of protection with antigen-specific antibody titer, but not with effector CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3400-11.
1997: Ahlers J D; Takeshita T; Pendleton C D; Berzofsky J A
Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):10856-61.
1997: Smith M C; Pendleton C D; Maher V E; Kelley M J; Carbone D P; Berzofsky J A
Oncogenic mutations in ras create HLA-A2.1 binding peptides but affect their extracellular antigen processing.
International immunology 1997;9(8):1085-93.
1997: Pinto L A; Landay A L; Berzofsky J A; Kessler H A; Shearer G M
Immune response to human immunodeficiency virus (HIV) in healthcare workers occupationally exposed to HIV-contaminated blood.
The American journal of medicine 1997;102(5B):21-4.
1997: Goletz T J; Klimpel K R; Leppla S H; Keith J M; Berzofsky J A
Delivery of antigens to the MHC class I pathway using bacterial toxins.
Human immunology 1997;54(2):129-36.
1997: Shirai M; Kozlowski S; Margulies D H; Berzofsky J A
Degenerate MHC restriction reveals the contribution of class I MHC molecules in determining the fine specificity of CTL recognition of an immunodominant determinant of HIV-1 gp160 V3 loop.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3181-8.
1997: Ahlers J D; Dunlop N; Alling D W; Nara P L; Berzofsky J A
Cytokine-in-adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs: granulocyte-macrophage colony-stimulating factor and TNF-alpha synergize with IL-12 to enhance induction of cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3947-58.
1997: Saito T; Sherman G J; Kurokohchi K; Guo Z P; Donets M; Yu M Y; Berzofsky J A; Akatsuka T; Feinstone S M
Plasmid DNA-based immunization for hepatitis C virus structural proteins: immune responses in mice.
Gastroenterology 1997;112(4):1321-30.
1997: Leggatt G R; Alexander-Miller M A; Kumar A; Hoffman S L; Berzofsky J A
Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes.
Journal of immunological methods 1997;201(1):1-10.
1997: Sarin A; Williams M S; Alexander-Miller M A; Berzofsky J A; Zacharchuk C M; Henkart P A
Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases.
Immunity 1997;6(2):209-15.
1996: Shirai M; Kurokohchi K; Pendleton C D; Arichi T; Boyd L F; Takahashi H; Margulies D H; Berzofsky J A
Reciprocal cytotoxic T lymphocyte cross-reactivity interactions between two major epitopes within HIV-1 gp160.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4399-411.
1996: Huang X; Smith M C; Berzofsky J A; Barchi J J
Structural comparison of a 15 residue peptide from the V3 loop of HIV-1IIIb and an O-glycosylated analogue.
FEBS letters 1996;393(2-3):280-6.
1996: Tsukui T; Hildesheim A; Schiffman M H; Lucci J; Contois D; Lawler P; Rush B B; Lorincz A T; Corrigan A; Burk R D; Qu W; Marshall M A; Mann D; Carrington M; Clerici M; Shearer G M; Carbone D P; Scott D R; Houghten R A; Berzofsky J A
Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology.
Cancer research 1996;56(17):3967-74.
1996: Alexander-Miller M A; Leggatt G R; Sarin A; Berzofsky J A
Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.
The Journal of experimental medicine 1996;184(2):485-92.
1996: Tian J H; Miller L H; Kaslow D C; Ahlers J; Good M F; Alling D W; Berzofsky J A; Kumar S
Genetic regulation of protective immune response in congenic strains of mice vaccinated with a subunit malaria vaccine.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(3):1176-83.
1996: Clerici M; Sarin A; Berzofsky J A; Landay A L; Kessler H A; Hashemi F; Hendrix C W; Blatt S P; Rusnak J; Dolan M J; Coffman R L; Henkart P A; Shearer G M
Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin.
AIDS (London, England) 1996;10(6):603-11.
1996: Alexander-Miller M A; Parker K C; Tsukui T; Pendleton C D; Coligan J E; Berzofsky J A
Molecular analysis of presentation by HLA-A2.1 of a promiscuously binding V3 loop peptide from the HIV-envelope protein to human cytotoxic T lymphocytes.
International immunology 1996;8(5):641-9.
1996: Landay A L; Clerici M; Hashemi F; Kessler H; Berzofsky J A; Shearer G M
In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10.
The Journal of infectious diseases 1996;173(5):1085-91.
1996: Kurokohchi K; Carrington M; Mann D L; Simonis T B; Alexander-Miller M A; Feinstone S M; Akatsuka T; Berzofsky J A
Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 1996;23(5):1181-8.
1996: Alexander-Miller M A; Leggatt G R; Berzofsky J A
Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4102-7.
1996: Ahlers J D; Dunlop N; Pendleton C D; Newman M; Nara P L; Berzofsky J A
Candidate HIV type 1 multideterminant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization.
AIDS research and human retroviruses 1996;12(4):259-72.
1996: Kullberg M C; Berzofsky J A; Jankovic D L; Barbieri S; Williams M E; Perlmann P; Sher A; Troye-Blomberg M
T cell-derived IL-3 induces the production of IL-4 by non-B, non-T cells to amplify the Th2-cytokine response to a non-parasite antigen in Schistosoma mansoni-infected mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1482-9.
1996: Shirai M; Chen M; Arichi T; Masaki T; Nishioka M; Newman M; Nakazawa T; Feinstone S M; Berzofsky J A
Use of intrinsic and extrinsic helper epitopes for in vivo induction of anti-hepatitis C virus cytotoxic T lymphocytes (CTL) with CTL epitope peptide vaccines.
The Journal of infectious diseases 1996;173(1):24-31.
1996: Kurokohchi K; Akatsuka T; Pendleton C D; Takamizawa A; Nishioka M; Battegay M; Feinstone S M; Berzofsky J A
Use of recombinant protein to identify a motif-negative human cytotoxic T-cell epitope presented by HLA-A2 in the hepatitis C virus NS3 region.
Journal of virology 1996;70(1):232-40.
1995: England R D; Kullberg M C; Cornette J L; Berzofsky J A
Molecular analysis of a heteroclitic T cell response to the immunodominant epitope of sperm whale myoglobin. Implications for peptide partial agonists.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4295-306.
1995: Pinto L A; Sullivan J; Berzofsky J A; Clerici M; Kessler H A; Landay A L; Shearer G M
ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.
The Journal of clinical investigation 1995;96(2):867-76.
1995: Berzofsky J A
Designing peptide vaccines to broaden recognition and enhance potency.
Annals of the New York Academy of Sciences 1995;754():161-8.
1995: Shirai M; Arichi T; Nishioka M; Nomura T; Ikeda K; Kawanishi K; Engelhard V H; Feinstone S M; Berzofsky J A
CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2733-42.
1995: Berzofsky J A; Berkower I J
Novel approaches to peptide and engineered protein vaccines for HIV using defined epitopes: advances in 1994-1995.
AIDS (London, England) 1995;9 Suppl A():S143-57.
1995: Shearer G M; Clerici M; Sarin A; Berzofsky J A; Henkart P A
Cytokines in immune regulation/pathogenesis in HIV infection.
Ciba Foundation symposium 1995;195():142-7; discussion 147-53.
1994: Berzofsky J A
Cross-fertilization among fields: a seminal event in the progress of biomedical research.
The Journal of clinical investigation 1994;94(3):911-8.
1994: Bermas B L; Petri M; Berzofsky J A; Waisman A; Shearer G M; Mozes E
Binding of glycoprotein 120 and peptides from the HIV-1 envelope by autoantibodies in mice with experimentally induced systemic lupus erythematosus and in patients with the disease.
AIDS research and human retroviruses 1994;10(9):1071-7.
1994: Kozhich A T; Kawano Y; Egwuagu C E; Caspi R R; Maturi R K; Berzofsky J A; Gery I
A pathogenic autoimmune process targeted at a surrogate epitope.
The Journal of experimental medicine 1994;180(1):133-40.
1994: Shirai M; Okada H; Nishioka M; Akatsuka T; Wychowski C; Houghten R; Pendleton C D; Feinstone S M; Berzofsky J A
An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans.
Journal of virology 1994;68(5):3334-42.
1994: Clerici M; Wynn T A; Berzofsky J A; Blatt S P; Hendrix C W; Sher A; Coffman R L; Shearer G M
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.
The Journal of clinical investigation 1994;93(2):768-75.
1994: Shirai M; Pendleton C D; Ahlers J; Takeshita T; Newman M; Berzofsky J A
Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):549-56.
1994: Clerici M; Levin J M; Kessler H A; Harris A; Berzofsky J A; Landay A L; Shearer G M
HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood.
JAMA : the journal of the American Medical Association 1994;271(1):42-6.
1993: Clerici M; Lucey D R; Berzofsky J A; Pinto L A; Wynn T A; Blatt S P; Dolan M J; Hendrix C W; Wolf S F; Shearer G M
Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro.
Science (New York, N.Y.) 1993;262(5140):1721-4.
1993: Clerici M; Sison A V; Berzofsky J A; Rakusan T A; Brandt C D; Ellaurie M; Villa M; Colie C; Venzon D J; Sever J L
Cellular immune factors associated with mother-to-infant transmission of HIV.
AIDS (London, England) 1993;7(11):1427-33.
1993: Kozlowski S; Corr M; Shirai M; Boyd L F; Pendleton C D; Berzofsky J A; Margulies D H
Multiple pathways are involved in the extracellular processing of MHC class I-restricted peptides.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(8):4033-44.
1993: Takeshita T; Kozlowski S; England R D; Brower R; Schneck J; Takahashi H; DeLisi C; Margulies D H; Berzofsky J A
Role of conserved regions of class I MHC molecules in the activation of CD8+ cytotoxic T lymphocytes by peptide and purified cell-free class I molecules.
International immunology 1993;5(9):1129-38.
1993: Williams M E; Kullberg M C; Barbieri S; Caspar P; Berzofsky J A; Seder R A; Sher A
Fc epsilon receptor-positive cells are a major source of antigen-induced interleukin-4 in spleens of mice infected with Schistosoma mansoni.
European journal of immunology 1993;23(8):1910-6.
1993: Berzofsky J A
Epitope selection and design of synthetic vaccines. Molecular approaches to enhancing immunogenicity and cross-reactivity of engineered vaccines.
Annals of the New York Academy of Sciences 1993;690():256-64.
1993: Shirai M; Vacchio M S; Hodes R J; Berzofsky J A
Preferential V beta usage by cytotoxic T cells cross-reactive between two epitopes of HIV-1 gp160 and degenerate in class I MHC restriction.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):2283-95.
1993: Yanuck M; Carbone D P; Pendleton C D; Tsukui T; Winter S F; Minna J D; Berzofsky J A
A mutant p53 tumor suppressor protein is a target for peptide-induced CD8+ cytotoxic T-cells.
Cancer research 1993;53(14):3257-61.
1993: Ahlers J D; Pendleton C D; Dunlop N; Minassian A; Nara P L; Berzofsky J A
Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(12):5647-65.
1992: Hosmalin A; Kumar S; Barnd D; Houghten R; Smith G E; Hughes S H; Berzofsky J A
Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1311-8.
1992: Shirai M; Akatsuka T; Pendleton C D; Houghten R; Wychowski C; Mihalik K; Feinstone S; Berzofsky J A
Induction of cytotoxic T cells to a cross-reactive epitope in the hepatitis C virus nonstructural RNA polymerase-like protein.
Journal of virology 1992;66(7):4098-106.
1992: Clerici M; Giorgi J V; Chou C C; Gudeman V K; Zack J A; Gupta P; Ho H N; Nishanian P G; Berzofsky J A; Shearer G M
Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1.
The Journal of infectious diseases 1992;165(6):1012-9.
1992: Sher A; Gazzinelli R T; Oswald I P; Clerici M; Kullberg M; Pearce E J; Berzofsky J A; Mosmann T R; James S L; Morse H C
Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection.
Immunological reviews 1992;127():183-204.
1992: Kozlowski S; Corr M; Takeshita T; Boyd L F; Pendleton C D; Germain R N; Berzofsky J A; Margulies D H
Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules.
The Journal of experimental medicine 1992;175(6):1417-22.
1992: Kullberg M C; Pearce E J; Hieny S E; Sher A; Berzofsky J A
Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(10):3264-70.
1992: Shirai M; Pendleton C D; Berzofsky J A
Broad recognition of cytotoxic T cell epitopes from the HIV-1 envelope protein with multiple class I histocompatibility molecules.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(6):1657-67.
1991: De Groot A S; Clerici M; Hosmalin A; Hughes S H; Barnd D; Hendrix C W; Houghten R; Shearer G M; Berzofsky J A
Human immunodeficiency virus reverse transcriptase T helper epitopes identified in mice and humans: correlation with a cytotoxic T cell epitope.
The Journal of infectious diseases 1991;164(6):1058-65.
1991: Berzofsky J A; Pendleton C D; Clerici M; Ahlers J; Lucey D R; Putney S D; Shearer G M
Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.
The Journal of clinical investigation 1991;88(3):876-84.
1991: Berzofsky J A
Antigenic peptide interaction with MHC molecules: implications for the design of artificial vaccines.
Seminars in immunology 1991;3(4):203-16.
1991: Clerici M; Berzofsky J A; Shearer G M; Tacket C O
Exposure to human immunodeficiency virus (HIV) type I indicated by HIV-specific T helper cell responses before detection of infection by polymerase chain reaction and serum antibodies [corrected]
The Journal of infectious diseases 1991;164(1):178-82.
1991: Berzofsky J A
Development of artificial vaccines against HIV using defined epitopes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(10):2412-8.
1991: Clerici M; Tacket C O; Via C S; Lucey D R; Muluk S C; Zajac R A; Boswell R N; Berzofsky J A; Shearer G M
Immunization with subunit human immunodeficiency virus vaccine generates stronger T helper cell immunity than natural infection.
European journal of immunology 1991;21(6):1345-9.
1991: Lipham W J; Redmond T M; Takahashi H; Berzofsky J A; Wiggert B; Chader G J; Gery I
Recognition of peptides that are immunopathogenic but cryptic. Mechanisms that allow lymphocytes sensitized against cryptic peptides to initiate pathogenic autoimmune processes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):3757-62.
1991: Clerici M; Lucey D R; Zajac R A; Boswell R N; Gebel H M; Takahashi H; Berzofsky J A; Shearer G M
Detection of cytotoxic T lymphocytes specific for synthetic peptides of gp160 in HIV-seropositive individuals.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2214-9.
1991: Berzofsky J A
Mechanisms of T cell recognition with application to vaccine design.
Molecular immunology 1991;28(3):217-23.
1991: Kozlowski S; Takeshita T; Boehncke W H; Takahashi H; Boyd L F; Germain R N; Berzofsky J A; Margulies D H
Excess beta 2 microglobulin promoting functional peptide association with purified soluble class I MHC molecules.
Nature 1991;349(6304):74-7.
1991: Berzofsky J A; Pendleton C D; Clerici M; Ahlers J; Lucey D R; Putney S D; Shearer G M
Peptides containing multideterminant clusters of human immunodeficiency virus envelope induce murine and human T-cell responses in diverse histocompatibility types.
Transactions of the Association of American Physicians 1991;104():69-77.
1991: Berzofsky J A
Progress toward an artificial vaccine for HIV: identification of helper and cytotoxic T-cell epitopes and methods of immunization.
Biotechnology therapeutics 1991;2(1-2):123-35.
1990: Kim J E; Kojima M; Houghten R; Pendleton C D; Cornette J L; DeLisi C; Berzofsky J A
Characterization of a helper T cell epitope recognized by mice of a low responder major histocompatibility type.
Molecular immunology 1990;27(10):941-6.
1990: Kurata A; Berzofsky J A
Analysis of peptide residues interacting with MHC molecule or T cell receptor. Can a peptide bind in more than one way to the same MHC molecule?
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4526-35.
1990: Takahashi H; Takeshita T; Morein B; Putney S; Germain R N; Berzofsky J A
Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs.
Nature 1990;344(6269):873-5.
1990: Kotake S; Wiggert B; Redmond T M; Borst D E; Nickerson J M; Margalit H; Berzofsky J A; Chader G J; Gery I
Repeated determinants within the retinal interphotoreceptor retinoid-binding protein (IRBP): immunological properties of the repeats of an immunodominant determinant.
Cellular immunology 1990;126(2):331-42.
1990: Hosmalin A; Clerici M; Houghten R; Pendleton C D; Flexner C; Lucey D R; Moss B; Germain R N; Shearer G M; Berzofsky J A
An epitope in human immunodeficiency virus 1 reverse transcriptase recognized by both mouse and human cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(6):2344-8.
1990: Vinetz J M; Kumar S; Good M F; Fowlkes B J; Berzofsky J A; Miller L H
Adoptive transfer of CD8+ T cells from immune animals does not transfer immunity to blood stage Plasmodium yoelii malaria.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(3):1069-74.
1990: Takahashi H; Germain R N; Moss B; Berzofsky J A
An immunodominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type 1 induces CD4 class II-restricted help for itself.
The Journal of experimental medicine 1990;171(2):571-6.
1990: Good M F; Kumar S; De Groot A S; Weiss W R; Quakyi I A; Dontfraid F; Smith G E; Cochran M; Berzofsky J A; Miller L H
Evidence implicating MHC genes in the immunological nonresponsiveness to the Plasmodium falciparum CS protein.
Bulletin of the World Health Organization 1990;68 Suppl():80-4.
1989: Takahashi H; Houghten R; Putney S D; Margulies D H; Moss B; Germain R N; Berzofsky J A
Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein.
The Journal of experimental medicine 1989;170(6):2023-35.
1989: Vacchio M S; Berzofsky J A; Krzych U; Smith J A; Hodes R J; Finnegan A
Sequences outside a minimal immunodominant site exert negative effects on recognition by staphylococcal nuclease-specific T cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(9):2814-9.
1989: Redmond T M; Sanui H; Hu L H; Wiggert B; Margalit H; Berzofsky J A; Chader G J; Gery I
Immune responses to peptides derived from the retinal protein IRBP: immunopathogenic determinants are not necessarily immunodominant.
Clinical immunology and immunopathology 1989;53(2 Pt 1):212-24.
1989: Takahashi H; Merli S; Putney S D; Houghten R; Moss B; Germain R N; Berzofsky J A
A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160.
Science (New York, N.Y.) 1989;246(4926):118-21.
1989: Kurata A; Palker T J; Streilein R D; Scearce R M; Haynes B F; Berzofsky J A
Immunodominant sites of human T cell lymphotropic virus type 1 envelope protein for murine helper T cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(6):2024-30.
1989: Brett S J; Cease K B; Ouyang C S; Berzofsky J A
Fine specificity of T cell recognition of the same peptide in association with different I-A molecules.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(3):771-9.
1989: Clerici M; Stocks N I; Zajac R A; Boswell R N; Bernstein D C; Mann D L; Shearer G M; Berzofsky J A
Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals.
Nature 1989;339(6223):383-5.
1989: Sanui H; Redmond T M; Kotake S; Wiggert B; Hu L H; Margalit H; Berzofsky J A; Chader G J; Gery I
Identification of an immunodominant and highly immunopathogenic determinant in the retinal interphotoreceptor retinoid-binding protein (IRBP).
The Journal of experimental medicine 1989;169(6):1947-60.
1989: de Groot A S; Johnson A H; Maloy W L; Quakyi I A; Riley E M; Menon A; Banks S M; Berzofsky J A; Good M F
Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(11):4000-5.
1989: Takahashi H; Cease K B; Berzofsky J A
Identification of proteases that process distinct epitopes on the same protein.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(7):2221-9.
1989: Brett S J; McKean D; York-Jolley J; Berzofsky J A
Antigen presentation to specific T cells by Ia molecules selectively altered by site-directed mutagenesis.
International immunology 1989;1(2):130-40.
1988: Berzofsky J A; Brett S J; Streicher H Z; Takahashi H
Antigen processing for presentation to T lymphocytes: function, mechanisms, and implications for the T-cell repertoire.
Immunological reviews 1988;106():5-31.
1988: Berzofsky J A
Structural basis of antigen recognition by T lymphocytes. Implications for vaccines.
The Journal of clinical investigation 1988;82(6):1811-7.
1988: Dontfraid F; Cochran M A; Pombo D; Knell J D; Quakyi I A; Kumar S; Houghten R A; Berzofsky J A; Miller L H; Good M F
Human and murine CD4 T cell epitopes map to the same region of the malaria circumsporozoite protein: limited immunogenicity of sporozoites and circumsporozoite protein.
Molecular biology & medicine 1988;5(3):185-96.
1988: Good M F; Miller L H; Kumar S; Quakyi I A; Keister D; Adams J H; Moss B; Berzofsky J A; Carter R
Limited immunological recognition of critical malaria vaccine candidate antigens.
Science (New York, N.Y.) 1988;242(4878):574-7.
1988: Good M F; Pombo D; Lunde M N; Maloy W L; Halenbeck R; Koths K; Miller L H; Berzofsky J A
Recombinant human IL-2 overcomes genetic nonresponsiveness to malaria sporozoite peptides. Correlation of effect with biologic activity of IL-2.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(3):972-7.
1988: Berzofsky J A; Bensussan A; Cease K B; Bourge J F; Cheynier R; Lurhuma Z; Salaün J J; Gallo R C; Shearer G M; Zagury D
Antigenic peptides recognized by T lymphocytes from AIDS viral envelope-immune humans.
Nature 1988;334(6184):706-8.
1988: Kumar S; Miller L H; Quakyi I A; Keister D B; Houghten R A; Maloy W L; Moss B; Berzofsky J A; Good M F
Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum.
Nature 1988;334(6179):258-60.
1988: Brett S J; Cease K B; Berzofsky J A
Influences of antigen processing on the expression of the T cell repertoire. Evidence for MHC-specific hindering structures on the products of processing.
The Journal of experimental medicine 1988;168(1):357-73.
1988: Ozaki S; Durum S K; Muegge K; York-Jolley J; Berzofsky J A
Production of T-T hybrids from T cell clones. Direct comparison between cloned T cells and T hybridoma cells derived from them.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(1):71-8.
1988: Takahashi H; Cohen J; Hosmalin A; Cease K B; Houghten R; Cornette J L; DeLisi C; Moss B; Germain R N; Berzofsky J A
An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(9):3105-9.
1988: Pombo D; Maloy W L; Berzofsky J A; Good M F
Neonatal exposure to immunogenic peptides. Differential susceptibility to tolerance induction of helper T cells and B cells reactive to malarial circumsporozoite peptide epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3594-8.
1988: Berzofsky J A
Features of T-cell recognition and antigen structure useful in the design of vaccines to elicit T-cell immunity.
Vaccine 1988;6(2):89-93.
1988: Good M F; Pombo D; Maloy W L; de la Cruz V F; Miller L H; Berzofsky J A
Parasite polymorphism present within minimal T cell epitopes of Plasmodium falciparum circumsporozoite protein.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1645-50.
1988: Kojima M; Cease K B; Buckenmeyer G K; Berzofsky J A
Limiting dilution comparison of the repertoires of high and low responder MHC-restricted T cells.
The Journal of experimental medicine 1988;167(3):1100-13.
1988: Good M F; Pombo D; Quakyi I A; Riley E M; Houghten R A; Menon A; Alling D W; Berzofsky J A; Miller L H
Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1199-203.
1988: Good M F; Berzofsky J A; Miller L H
The T cell response to the malaria circumsporozoite protein: an immunological approach to vaccine development.
Annual review of immunology 1988;6():663-88.
1988: Berzofsky J A
Mechanisms of immunodominance in T-cell recognition, with applications to vaccine design.
Princess Takamatsu symposia 1988;19():161-77.
1987: Berzofsky J A; Cease K B; Cornette J L; Spouge J L; Margalit H; Berkower I J; Good M F; Miller L H; DeLisi C
Protein antigenic structures recognized by T cells: potential applications to vaccine design.
Immunological reviews 1987;98():9-52.
1987: Cornette J L; Cease K B; Margalit H; Spouge J L; Berzofsky J A; DeLisi C
Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins.
Journal of molecular biology 1987;195(3):659-85.
1987: Takacs L; Berzofsky J A; York-Jolley J; Akahoshi T; Blasi E; Durum S K
IL 1 induction by murine T cell clones: detection of an IL 1-inducing lymphokine.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(7):2124-31.
1987: Margalit H; Spouge J L; Cornette J L; Cease K B; Delisi C; Berzofsky J A
Prediction of immunodominant helper T cell antigenic sites from the primary sequence.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(7):2213-29.
1987: Spouge J L; Guy H R; Cornette J L; Margalit H; Cease K; Berzofsky J A; DeLisi C
Strong conformational propensities enhance T cell antigenicity.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(1):204-12.
1986: Cease K B; Berkower I; York-Jolley J; Berzofsky J A
T cell clones specific for an amphipathic alpha-helical region of sperm whale myoglobin show differing fine specificities for synthetic peptides. A multiview/single structure interpretation of immunodominance.
The Journal of experimental medicine 1986;164(5):1779-84.
1986: Cease K B; Buckenmeyer G; Berkower I; York-Jolley J; Berzofsky J A
Immunologically relevant peptide antigen exists on the presenting cell in a manner accessible to macromolecules in solution.
The Journal of experimental medicine 1986;164(5):1440-54.
1986: Berkower I; Buckenmeyer G K; Berzofsky J A
Molecular mapping of a histocompatibility-restricted immunodominant T cell epitope with synthetic and natural peptides: implications for T cell antigenic structure.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(7):2498-503.
1986: Streicher H Z; Cuttitta F; Buckenmeyer G K; Kawamura H; Minna J; Berzofsky J A
Mapping the idiotopes of a monoclonal anti-myoglobin antibody with syngeneic monoclonal anti-idiotypic antibodies: detection of a common idiotope.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(3):1007-14.
1984: Streicher H Z; Berkower I J; Busch M; Gurd F R; Berzofsky J A
Antigen conformation determines processing requirements for T-cell activation.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(21):6831-5.
1984: Berkower I; Matis L A; Buckenmeyer G K; Gurd F R; Longo D L; Berzofsky J A
Identification of distinct predominant epitopes recognized by myoglobin-specific T cells under the control of different Ir genes and characterization of representative T cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(3):1370-8.
1982: Berkower I; Buckenmeyer G K; Gurd F R; Berzofsky J A
A possible immunodominant epitope recognized by murine T lymphocytes immune to different myoglobins.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(15):4723-7.
1982: Berzofsky J A; Buckenmeyer G K; Hicks G; Gurd F R; Feldmann R J; Minna J
Topographic antigenic determinants recognized by monoclonal antibodies to sperm whale myoglobin.
The Journal of biological chemistry 1982;257(6):3189-98.
1982: Berzofsky J A; Buckenmeyer G K; Hicks G
Genetic control of the immune response to myoglobins. VI. Distinct Ir genes for different myoglobins: complementing genes in I-A and H-2D for equine myoglobin.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(2):737-41.
1980: Berzofsky J A; Hicks G; Fedorko J; Minna J
Properties of monoclonal antibodies specific for determinants of a protein antigen, myoglobin.
The Journal of biological chemistry 1980;255(23):11188-91.

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