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Sahdeo Prasad

Research Profile

Chemicals & Drugs

Anatomy

Tumor Cell Line

Physiology

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Publications

TOP 3
Bokyung Sung; Vivek R Yadav; Sahdeo Prasad; Jayaraj Ravindran; Bharat B Aggarwal
Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
Sahdeo Prasad; Simone Reuter; Bokyung Sung; Caimiao Wei; Vivek R Yadav; Veerabhadran Baladandayuthapani; Amit Deorukhkar; Parmeswaran Diagaradjane; Sushovan Guha; Ramaswamy Kannappan; Sunil Krishnan; Bharat B Aggarwal
Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Sahdeo Prasad; Bokyung Sung; Bharat B Aggarwal
Age-associated chronic diseases require age-old medicine: role of chronic inflammation.

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All Publications

2012: Bokyung Sung; Vivek R Yadav; Sahdeo Prasad; Jayaraj Ravindran; Bharat B Aggarwal
Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
Free radical biology & medicine 2012;53(10):1977-87.
2012: Sahdeo Prasad; Simone Reuter; Bokyung Sung; Caimiao Wei; Vivek R Yadav; Veerabhadran Baladandayuthapani; Amit Deorukhkar; Parmeswaran Diagaradjane; Sushovan Guha; Ramaswamy Kannappan; Sunil Krishnan; Bharat B Aggarwal
Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(18):4942-53.
2012: Sahdeo Prasad; Bokyung Sung; Bharat B Aggarwal
Age-associated chronic diseases require age-old medicine: role of chronic inflammation.
Preventive medicine 2012;54 Suppl():S29-37.
2012: Vivek R Yadav; Juri G Gelovani; Sushovan Guha; Sunil Krishnan; Sahdeo Prasad; Bokyung Sung; Bharat B Aggarwal
Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers.
International journal of cancer. Journal international du cancer 2012;130(9):2176-84.
2012: Bokyung Sung; Vivek R Yadav; Sahdeo Prasad; Bharat B Aggarwal
Cancer cell signaling pathways targeted by spice-derived nutraceuticals.
Nutrition and cancer 2012;64(2):173-97.
2011: Subash C Gupta; Ji Hye Kim; Sridevi Patchva; Sahdeo Prasad; Indira K Priyadarsini; Lauren J Webb; Bharat B Aggarwal
Multitargeting by curcumin as revealed by molecular interaction studies.
Natural product reports 2011;28(12):1937-55.
2011: Kanokkarn Phromnoi; Sahdeo Prasad; Simone Reuter; Subash C Gupta; Ramaswamy Kannappan; Pornngarm Limtrakul; Bharat B Aggarwal
Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1.
Molecular pharmacology 2011;80(5):889-99.
2011: Bharat B Aggarwal; Madan M Chaturvedi; Subash C Gupta; Ramaswamy Kannappan; Ji Hye Kim; Byoungduck Park; Kanokkarn Phromnoi; Sahdeo Prasad; Seema Prasad; Simone Reuter; Chitra Sundaram; Vivek R Yadev; Bokyung Sung
Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.
Current drug targets 2011;12(11):1595-653.
2011: Bokyung Sung; Vivek R Yadav; Afsaneh Lavasanifar; Sahdeo Prasad; Bharat B Aggarwal
Cancer and diet: How are they related?
Free radical research 2011;45(8):864-79.
2011: Sahdeo Prasad; Vivek R Yadav; Manoj Pandey; Bharat B Aggarwal
Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis.
Cancer prevention research (Philadelphia, Pa.) 2011;4(7):1084-94.
2011: Vivek R Yadav; Sahdeo Prasad; Bokyung Sung; Bharat B Aggarwal
The role of chalcones in suppression of NF-κB-mediated inflammation and cancer.
International immunopharmacology 2011;11(3):295-309.
2011: Sahdeo Prasad; Vivek R Yadav; Ramaswamy Kannappan; Bharat B Aggarwal
Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
The Journal of biological chemistry 2011;286(7):5546-57.
2011: Kanokkarn Phromnoi; Simone Reuter; Bokyung Sung; Sahdeo Prasad; Ramaswamy Kannappan; Vivek R Yadav; Wisinee Chanmahasathien; Pornngarm Limtrakul; Bharat B Aggarwal
A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.
Molecular pharmacology 2011;79(2):279-89.
2011: Sahdeo Prasad; Vivek R Yadav; Jayaraj Ravindran; Bharat B Aggarwal
ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.
Cancer research 2011;71(2):538-49.
2011: Byoungduck Park; Sahdeo Prasad; Bokyung Sung; Vivek Yadav; Bharat B Aggarwal
Boswellic acid suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude mouse model through modulation of multiple targets.
PloS one 2011;6(10):e26943.
2010: Vivek R Yadav; Bokyung Sung; Sahdeo Prasad; Ramaswamy Kannappan; Sung Gook Cho; Mingyao Liu; Madan M Chaturvedi; Bharat B Aggarwal
Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.
Journal of molecular medicine (Berlin, Germany) 2010;88(12):1243-53.
2010: Bokyung Sung; Jayaraj Ravindran; Sahdeo Prasad; Manoj Pandey; Bharat B Aggarwal
Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
The Journal of biological chemistry 2010;285(46):35418-27.
2010: Subash C Gupta; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadav; Jayaraj Ravindran; Padmanabhan S Hema; Madan M Chaturvedi; Mangalam Nair; Bharat B Aggarwal
Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents.
The Journal of biological chemistry 2010;285(46):35406-17.
2010: Simone Reuter; Sahdeo Prasad; Kanokkarn Phromnoi; Jayaraj Ravindran; Bokyung Sung; Vivek R Yadav; Ramaswamy Kannappan; Madan M Chaturvedi; Bharat B Aggarwal
Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer.
Cancer prevention research (Philadelphia, Pa.) 2010;3(11):1462-72.
2010: Vivek R Yadav; Ramaswamy Kannappan; Sahdeo Prasad; Bokyung Sung; Bharat B Aggarwal
Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.
Toxins 2010;2(10):2428-66.
2010: Simone Reuter; Sahdeo Prasad; Kanokkarn Phromnoi; Ramaswamy Kannappan; Vivek R Yadav; Bharat B Aggarwal
Embelin suppresses osteoclastogenesis induced by receptor activator of NF-κB ligand and tumor cells in vitro through inhibition of the NF-κB cell signaling pathway.
Molecular cancer research : MCR 2010;8(10):1425-36.
2010: Vivek R Yadav; Sahdeo Prasad; Ramaswamy Kannappan; Jayaraj Ravindran; Madan M Chaturvedi; Lauri Vaahtera; Jaakko Parkkinen; Bharat B Aggarwal
Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake.
Biochemical pharmacology 2010;80(7):1021-32.
2010: Subash C Gupta; Ji Hye Kim; Sahdeo Prasad; Bharat B Aggarwal
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals.
Cancer metastasis reviews 2010;29(3):405-34.
2010: Vinay Kumar Yadav; Sahdeo Prasad; Devendra K Patel; Altaf Husain Khan; Madhu Tripathi; Yogeshwer Shukla
Identification of polycyclic aromatic hydrocarbons in unleaded petrol and diesel exhaust emission.
Environmental monitoring and assessment 2010;168(1-4):173-8.
2010: Sahdeo Prasad; Vivek R Yadav; Chitra Sundaram; Simone Reuter; Padmanabhan S Hema; Mangalam S Nair; Madan M Chaturvedi; Bharat B Aggarwal
Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway.
The Journal of biological chemistry 2010;285(35):26987-97.
2010: Ramaswamy Kannappan; Jayaraj Ravindran; Sahdeo Prasad; Bokyung Sung; Vivek R Yadav; Simone Reuter; Madan M Chaturvedi; Bharat B Aggarwal
Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors.
Molecular cancer therapeutics 2010;9(8):2196-207.
2010: Sahdeo Prasad; Kannokarn Phromnoi; Vivek R Yadav; Madan M Chaturvedi; Bharat B Aggarwal
Targeting inflammatory pathways by flavonoids for prevention and treatment of cancer.
Planta medica 2010;76(11):1044-63.
2010: Jayaraj Ravindran; Hareesh B. Nair; Bokyung Sung; Sahdeo Prasad; Rajeshwar Tekmal; Bharat B Aggarwal
Thymoquinone poly (lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential.
Biochemical pharmacology 2010;79(11):1640-7.
2010: Madhulika Singh; Shilpa Tyagi; Kulpreet Bhui; Sahdeo Prasad; Yogeshwer Shukla
Regulation of cell growth through cell cycle arrest and apoptosis in HPV 16 positive human cervical cancer cells by tea polyphenols.
Investigational new drugs 2010;28(3):216-24.
2010: Sahdeo Prasad; Jayaraj Ravindran; Bokyung Sung; Manoj K Pandey; Bharat B Aggarwal
Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.
Molecular cancer therapeutics 2010;9(4):856-68.
2010: Jasmine George; Sahdeo Prasad; Zafar Mahmood; Yogeshwer Shukla
Studies on glyphosate-induced carcinogenicity in mouse skin: a proteomic approach.
Journal of proteomics 2010;73(5):951-64.
2010: Sahdeo Prasad; Jayaraj Ravindran; Bharat B Aggarwal
NF-kappaB and cancer: how intimate is this relationship.
Molecular and cellular biochemistry 2010;336(1-2):25-37.
2009: Smita Srivastava; Madhulika Singh; Jasmine George; Sahdeo Prasad; Preeti Roy; Yogeshwer Shukla
Inhibitory effect of tea polyphenols on hepatic preneoplastic foci in Wistar rats.
Investigational new drugs 2009;27(6):526-33.
2009: Kulpreet Bhui; Sahdeo Prasad; Jasmine George; Yogeshwer Shukla
Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway.
Cancer letters 2009;282(2):167-76.
2009: Nidhi Nigam; Kulpreet Bhui; Sahdeo Prasad; Jasmine George; Yogeshwer Shukla
[6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells.
Chemico-biological interactions 2009;181(1):77-84.
2009: Sahdeo Prasad; Esha Madan; Nidhi Nigam; Preeti Roy; Jasmine George; Yogeshwer Shukla
Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways.
Cancer biology & therapy 2009;8(17):1632-9.
2009: Jayaraj Ravindran; Sahdeo Prasad; Bharat B Aggarwal
Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?
The AAPS journal 2009;11(3):495-510.
2009: Preeti Roy; Esha Madan; Neetu Kalra; Nidhi Nigam; Jasmine George; Ratan Singh Ray; Rajendra Kumar Hans; Sahdeo Prasad; Yogeshwer Shukla
Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-kappaB pathway in human epidermoid carcinoma A431 cells.
Biochemical and biophysical research communications 2009;384(2):215-20.
2009: Nidhi Nigam; Sahdeo Prasad; Jasmine George; Yogeshwer Shukla
Lupeol induces p53 and cyclin-B-mediated G2/M arrest and targets apoptosis through activation of caspase in mouse skin.
Biochemical and biophysical research communications 2009;381(2):253-8.
2009: Sahdeo Prasad; Smita Srivastava; Madhulika Singh; Yogeshwer Shukla
Clastogenic effects of glyphosate in bone marrow cells of swiss albino mice.
Journal of toxicology 2009;2009():308985.
2008: Esha Madan; Sahdeo Prasad; Preeti Roy; Jasmine George; Yogeshwer Shukla
Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells.
Biochemical and biophysical research communications 2008;377(4):1232-7.
2008: Sahdeo Prasad; Nidhi Nigam; Neetu Kalra; Yogeshwer Shukla
Regulation of signaling pathways involved in lupeol induced inhibition of proliferation and induction of apoptosis in human prostate cancer cells.
Molecular carcinogenesis 2008;47(12):916-24.
2008: Sahdeo Prasad; Vinay Kumar Yadav; Smita Srivastava; Yogeshwer Shukla
Protective effects of lupeol against benzo[a]pyrene induced clastogenicity in mouse bone marrow cells.
Molecular nutrition & food research 2008;52(10):1117-20.
2008: Sahdeo Prasad; Neetu Kalra; Madhulika Singh; Yogeshwer Shukla
Protective effects of lupeol and mango extract against androgen induced oxidative stress in Swiss albino mice.
Asian journal of andrology 2008;10(2):313-8.
2008: Neetu Kalra; Preeti Roy; Sahdeo Prasad; Yogeshwer Shukla
Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis.
Life sciences 2008;82(7-8):348-58.
2008: Sahdeo Prasad; Neetu Kalra; Yogeshwer Shukla
Induction of apoptosis by lupeol and mango extract in mouse prostate and LNCaP cells.
Nutrition and cancer 2008;60(1):120-30.
2008: Neetu Kalra; Kulpreet Bhui; Preeti Roy; Smita Srivastava; Jasmine George; Sahdeo Prasad; Yogeshwer Shukla
Regulation of p53, nuclear factor kappaB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin.
Toxicology and applied pharmacology 2008;226(1):30-7.
2007: Yogeshwer Shukla; Sahdeo Prasad; Chitra Tripathi; Madhulika Singh; Jasmine George; Neetu Kalra
In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol.
Molecular nutrition & food research 2007;51(12):1492-502.
2007: Nidhi Nigam; Sahdeo Prasad; Yogeshwer Shukla
Preventive effects of lupeol on DMBA induced DNA alkylation damage in mouse skin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(11):2331-5.
2007: Sahdeo Prasad; Jaspreet Kaur; Preeti Roy; Neetu Kalra; Yogeshwer Shukla
Theaflavins induce G2/M arrest by modulating expression of p21waf1/cip1, cdc25C and cyclin B in human prostate carcinoma PC-3 cells.
Life sciences 2007;81(17-18):1323-31.
2007: Neetu Kalra; Kavita Seth; Sahdeo Prasad; Madhulika Singh; Aditya Pant; Yogeshwer Shukla
Theaflavins induced apoptosis of LNCaP cells is mediated through induction of p53, down-regulation of NF-kappa B and mitogen-activated protein kinases pathways.
Life sciences 2007;80(23):2137-46.
2007: Sahdeo Prasad; Neetu Kalra; Yogeshwer Shukla
Hepatoprotective effects of lupeol and mango pulp extract of carcinogen induced alteration in Swiss albino mice.
Molecular nutrition & food research 2007;51(3):352-9.
2006: Sahdeo Prasad; Neetu Kalra; Yogeshwer Shukla
Modulatory effects of diallyl sulfide against testosterone- induced oxidative stress in Swiss albino mice.
Asian journal of andrology 2006;8(6):719-23.
2006: Madhulika Singh; Sahdeo Prasad; Neetu Kalra; Uma Singh; Yogeshwer Shukla
Silver-stained nucleolar organizer regions in normal and dysplastic cervical lesions: correlation with DNA ploidy and S-phase fraction by flow cytometry.
Oncology 2006;71(5-6):411-6.
2005: Neetu Kalra; Sahdeo Prasad; Yogeshwer Shukla
Antioxidant potential of black tea against 7,12-dimethylbenz(a)anthracene- induced oxidative stress in Swiss albino mice.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2005;24(2):105-14.