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Graziella Pratesi

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TOP 3
Michele Sommariva; Elda Tagliabue; Valentina Uva; Nadia Zaffaroni; Loris De Cecco; Michelandrea De Cesare; Domenico Delia; Cecilia Melani; Sylvie Ménard; Graziella Pratesi; Lucia Sfondrini; Andrea Balsari
TLR9 agonists oppositely modulate DNA repair genes in tumor versus immune cells and enhance chemotherapy effects.
Nicola Ferri; Maria Luisa Gelmi; Graziella Pratesi; Tiziano Radice; Enzio Ragg; Stella Tinelli; Franco Zunino; Manuela Antonino; Egle Maria Beccalli; Alberto Corsini; Alessandro Contini
Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides.
Michelandrea De Cesare; Lucia Sfondrini; Manuela Campiglio; Michele Sommariva; Francesca Bianchi; Paola Perego; Nico van Rooijen; Rosanna Supino; Cristiano Rumio; Franco Zunino; Graziella Pratesi; Elda Tagliabue; Andrea Balsari
Ascites regression and survival increase in mice bearing advanced-stage human ovarian carcinomas and repeatedly treated intraperitoneally with CpG-ODN.

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All Publications

2011: Michele Sommariva; Elda Tagliabue; Valentina Uva; Nadia Zaffaroni; Loris De Cecco; Michelandrea De Cesare; Domenico Delia; Cecilia Melani; Sylvie Ménard; Graziella Pratesi; Lucia Sfondrini; Andrea Balsari
TLR9 agonists oppositely modulate DNA repair genes in tumor versus immune cells and enhance chemotherapy effects.
Cancer research 2011;71(20):6382-90.
2011: Nicola Ferri; Maria Luisa Gelmi; Graziella Pratesi; Tiziano Radice; Enzio Ragg; Stella Tinelli; Franco Zunino; Manuela Antonino; Egle Maria Beccalli; Alberto Corsini; Alessandro Contini
Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides.
Bioorganic & medicinal chemistry 2011;19(18):5291-9.
2010: Michelandrea De Cesare; Lucia Sfondrini; Manuela Campiglio; Michele Sommariva; Francesca Bianchi; Paola Perego; Nico van Rooijen; Rosanna Supino; Cristiano Rumio; Franco Zunino; Graziella Pratesi; Elda Tagliabue; Andrea Balsari
Ascites regression and survival increase in mice bearing advanced-stage human ovarian carcinomas and repeatedly treated intraperitoneally with CpG-ODN.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(1):8-15.
2009: Francesca Colombo; F Stefania Falvella; Loris De Cecco; Monica Tortoreto; Graziella Pratesi; Pierangela Ciuffreda; Roberta Ottria; Enzo Santaniello; Luigi Cicatiello; Alessandro Weisz; Tommaso A Dragani
Pharmacogenomics and analogues of the antitumour agent N6-isopentenyladenosine.
International journal of cancer. Journal international du cancer 2009;124(9):2179-85.
2008: Claudio Pisano; Michelandrea De Cesare; Giovanni Luca Beretta; Valentina Zuco; Graziella Pratesi; Sergio Penco; Loredana Vesci; Rosanna Foderà; Fabiana Fosca Ferrara; Mario Berardino Guglielmi; Paolo Carminati; Sabrina Dallavalle; Gabriella Morini; Lucio Merlini; Augusto Orlandi; Franco Zunino
Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.
Molecular cancer therapeutics 2008;7(7):2051-9.
2008: Graziella Pratesi; Giovanna Petrangolini; Monica Tortoreto; Alessandro Addis; Franco Zunino; Claudia Calcaterra; Andrea Merlo; Elda Tagliabue; Sylvie Menard; Andrea Balsari
Antitumor efficacy of trastuzumab in nude mice orthotopically xenografted with human pancreatic tumor cells expressing low levels of HER-2/neu.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(6):537-44.
2008: Giovanna Petrangolini; Monica Tortoreto; Paola Perego; Nives Carenini; Michelandrea De Cesare; Andrea Balsari; Franco Zunino; Graziella Pratesi
Combination of metronomic gimatecan and CpG-oligodeoxynucleotides against an orthotopic pancreatic cancer xenograft.
Cancer biology & therapy 2008;7(4):596-601.
2008: Daniele Passarella; Francesca Belinghieri; Michele Scarpellini; Graziella Pratesi; Franco Zunino; Ornella Maria Gia; Lisa Dalla Via; Giuseppe Santoro; Bruno Danieli
Synthesis and biological evaluation of pyrroloiminoquinone derivatives.
Bioorganic & medicinal chemistry 2008;16(5):2431-8.
2008: Nicola Ferri; Egle Maria Beccalli; Alessandro Contini; Alberto Corsini; Manuela Antonino; Tiziano Radice; Graziella Pratesi; Stella Tinelli; Franco Zunino; Maria Luisa Gelmi
Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3-heteroarylmaleimides and heterofused imides.
Bioorganic & medicinal chemistry 2008;16(4):1691-701.
2008: Rosanna Supino; Giovanna Petrangolini; Graziella Pratesi; Monica Tortoreto; Enrica Favini; Laura Dal Bo; Patrizia Casalini; Enrico Radaelli; Anna Cleta Croce; Giovanni Bottiroli; Paola Misiano; Carlo Farina; Franco Zunino
Antimetastatic effect of a small-molecule vacuolar H+-ATPase inhibitor in in vitro and in vivo preclinical studies.
The Journal of pharmacology and experimental therapeutics 2008;324(1):15-22.
2007: Claudio Pisano; Loredana Vesci; R Foderà; Fabiana Fosca Ferrara; C Rossi; Michelandrea De Cesare; Valentina Zuco; Graziella Pratesi; Rosanna Supino; Franco Zunino
Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(9):1500-5.
2007: Michelandrea De Cesare; Giovanni Luca Beretta; Stella Tinelli; Valentina Benedetti; Graziella Pratesi; Sergio Penco; Sabrina Dallavalle; Lucio Merlini; Claudio Pisano; Paolo Carminati; Franco Zunino
Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series.
Biochemical pharmacology 2007;73(5):656-64.
2006: Marco Clericuzio; Silvia Tabasso; Maria Ausilia Bianco; Graziella Pratesi; Giovanni Luca Beretta; Stella Tinelli; Franco Zunino; Giovanni Vidari
Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus.
Journal of natural products 2006;69(12):1796-9.
2006: Giovanni Luca Beretta; Giovanna Petrangolini; Michelandrea De Cesare; Graziella Pratesi; Paola Perego; Stella Tinelli; Monica Tortoreto; Massimo Zucchetti; Roberta Frapolli; Ezia Bello; Carla Manzotti; Gabriele Fontana; Ezio Bombardelli; Arturo Battaglia; Cristian Samori; Franco Zunino
Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.
Cancer research 2006;66(22):10976-82.
2006: Giuliana Cassinelli; Cinzia Lanzi; Giovanna Petrangolini; Monica Tortoreto; Graziella Pratesi; Giuditta Cuccuru; Diletta Laccabue; Rosanna Supino; Sara Belluco; Enrica Favini; Anna Poletti; Franco Zunino
Inhibition of c-Met and prevention of spontaneous metastatic spreading by the 2-indolinone RPI-1.
Molecular cancer therapeutics 2006;5(9):2388-97.
2006: Giovanna Petrangolini; Rosanna Supino; Graziella Pratesi; Laura Dal Bo; Monica Tortoreto; Anna Cleta Croce; Paola Misiano; Pietro Belfiore; Carlo Farina; Franco Zunino
Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins.
The Journal of pharmacology and experimental therapeutics 2006;318(3):939-46.
2006: Giovanna Petrangolini; Giuditta Cuccuru; Cinzia Lanzi; Monica Tortoreto; Sara Belluco; Graziella Pratesi; Giuliana Cassinelli; Franco Zunino
Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1.
Biochemical pharmacology 2006;72(4):405-14.
2006: Bruno Danieli; Alessandra Giardini; Giordano Lesma; Daniele Passarella; Bruno Peretto; Alessandro Sacchetti; Alessandra Silvani; Graziella Pratesi; Franco Zunino
Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction.
The Journal of organic chemistry 2006;71(7):2848-53.
2005: Eleonora Rizzi; Sabrina Dallavalle; Lucio Merlini; Giovanni Luca Beretta; Graziella Pratesi; Franco Zunino
A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin.
Bioorganic & medicinal chemistry letters 2005;15(19):4313-6.
2005: Graziella Pratesi; Giovanna Petrangolini; Monica Tortoreto; Alessandro Addis; Sara Belluco; Anna Rossini; Silvia Selleri; Cristiano Rumio; Sylvie Menard; Andrea Balsari
Therapeutic synergism of gemcitabine and CpG-oligodeoxynucleotides in an orthotopic human pancreatic carcinoma xenograft.
Cancer research 2005;65(14):6388-93.
2005: Dario Ponti; Aurora Costa; Nadia Zaffaroni; Graziella Pratesi; Giovanna Petrangolini; Danila Coradini; Silvana Pilotti; Marco A Pierotti; Maria Grazia Daidone
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties.
Cancer research 2005;65(13):5506-11.
2005: Michelandrea De Cesare; Paola Perego; Sabina C Righetti; Graziella Pratesi; Nives Carenini; Licia Rivoltini; Gabriella Zupi; Donatella Del Bufalo; Andrea Balsari; Franco Zunino
Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.
European journal of cancer (Oxford, England : 1990) 2005;41(8):1213-22.
2004: Michelandrea De Cesare; Graziella Pratesi; Silvia Veneroni; Raffaella Bergottini; Franco Zunino
Efficacy of the novel camptothecin gimatecan against orthotopic and metastatic human tumor xenograft models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(21):7357-64.
2004: Elena Zarini; Rosanna Supino; Graziella Pratesi; Diletta Laccabue; Monica Tortoreto; Eugenio Scanziani; Gabriele Ghisleni; Saverio Paltrinieri; Gianfranco Tunesi; Maurizio Nava
Biocompatibility and tissue interactions of a new filler material for medical use.
Plastic and reconstructive surgery 2004;114(4):934-42.
2004: Giuditta Cuccuru; Cinzia Lanzi; Giuliana Cassinelli; Graziella Pratesi; Monica Tortoreto; Giovanna Petrangolini; Ettore Seregni; Antonia Martinetti; Diletta Laccabue; Chiara Zanchi; Franco Zunino
Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma.
Journal of the National Cancer Institute 2004;96(13):1006-14.
2004: Graziella Pratesi; Giovanni L Beretta; Franco Zunino
Gimatecan, a novel camptothecin with a promising preclinical profile.
Anti-cancer drugs 2004;15(6):545-52.
2004: Marzia Pennati; Mara Binda; Michelandrea De Cesare; Graziella Pratesi; Marco Folini; Lorenzo Citti; Maria Grazia Daidone; Franco Zunino; Nadia Zaffaroni
Ribozyme-mediated down-regulation of survivin expression sensitizes human melanoma cells to topotecan in vitro and in vivo.
Carcinogenesis 2004;25(7):1129-36.
2004: Andrea Balsari; Monica Tortoreto; Dario Besusso; Giovanna Petrangolini; Lucia Sfondrini; Roberto Maggi; Sylvie Ménard; Graziella Pratesi
Combination of a CpG-oligodeoxynucleotide and a topoisomerase I inhibitor in the therapy of human tumour xenografts.
European journal of cancer (Oxford, England : 1990) 2004;40(8):1275-81.
2004: Giovanna Petrangolini; Giuliana Cassinelli; Graziella Pratesi; Monica Tortoreto; Enrica Favini; Rosanna Supino; Cinzia Lanzi; Sara Belluco; Franco Zunino
Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft.
British journal of cancer 2004;90(7):1464-8.
2004: Franco Zunino; Graziella Pratesi
Camptothecins in clinical development.
Expert opinion on investigational drugs 2004;13(3):269-84.
2004: Marzia Pennati; Mara Binda; Gennaro Colella; Monica Zoppe'; Marco Folini; Sara Vignati; Alessandra Valentini; Lorenzo Citti; Michelandrea De Cesare; Graziella Pratesi; Mauro Giacca; Maria Grazia Daidone; Nadia Zaffaroni
Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells.
Oncogene 2004;23(2):386-94.
2003: Claudio Pisano; Graziella Pratesi; Diletta Laccabue; Franco Zunino; Pietro Lo Giudice; Augusta Bellucci; Licia Pacifici; Barbara Camerini; Loredana Vesci; Massimo Castorina; Sandra Cicuzza; Giovanni Tredici; Paola Marmiroli; Gabriella Nicolini; Sara Galbiati; Menotti Calvani; Paolo Carminati; Guido Cavaletti
Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5756-67.
2003: Giovanna Petrangolini; Graziella Pratesi; Michelandrea De Cesare; Rosanna Supino; Claudio Pisano; Marcella Marcellini; Vincenzo Giordano; Diletta Laccabue; Cinzia Lanzi; Franco Zunino
Antiangiogenic effects of the novel camptothecin ST1481 (gimatecan) in human tumor xenografts.
Molecular cancer research : MCR 2003;1(12):863-70.
2003: Valentina Zuco; Rosanna Supino; Michelandrea De Cesare; Nives Carenini; Paola Perego; Laura Gatti; Graziella Pratesi; Claudio Pisano; Roberta Martinelli; Federica Bucci; Romina Zanier; Paolo Carminati; Franco Zunino
Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models.
Biochemical pharmacology 2003;65(8):1281-94.
2003: Graziella Pratesi; Diletta Laccabue; Cinzia Lanzi; Giuliana Cassinelli; Rosanna Supino; Massimo Zucchetti; Roberta Frapolli; Maurizio D'Incalci; Ezio Bombardelli; Paolo Morazzoni; Antonella Riva; Franco Zunino
IDN 5390: an oral taxane candidate for protracted treatment schedules.
British journal of cancer 2003;88(6):965-72.
2002: Graziella Pratesi; Michelandrea De Cesare; Nives Carenini; Paola Perego; Sabina C Righetti; Carla Cucco; Lucio Merlini; Claudio Pisano; Sergio Penco; Paolo Carminati; Loredana Vesci; Franco Zunino
Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3904-9.
2002: Giuliana Cassinelli; Cinzia Lanzi; Rosanna Supino; Graziella Pratesi; Valentina Zuco; Diletta Laccabue; Giuditta Cuccuru; Ezio Bombardelli; Franco Zunino
Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(8):2647-54.
2001: Diletta Laccabue; Monica Tortoreto; Silvia Veneroni; Paola Perego; Eugenio Scanziani; Massimo Zucchetti; Marco Zaffaroni; Maurizio D'Incalci; Ezio Bombardelli; Franco Zunino; Graziella Pratesi
A novel taxane active against an orthotopically growing human glioma xenograft.
Cancer 2001;92(12):3085-92.
2001: Michelandrea De Cesare; Graziella Pratesi; Paola Perego; Nives Carenini; Stella Tinelli; Lucio Merlini; Sergio Penco; Claudio Pisano; Federica Bucci; Loredana Vesci; S Pace; F Capocasa; Paolo Carminati; Franco Zunino
Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin.
Cancer research 2001;61(19):7189-95.
2001: Sabrina Dallavalle; A Ferrari; Barbara Biasotti; Lucio Merlini; Sergio Penco; Grazia Gallo; MAURO MARZI; Maria Ornella Tinti; Roberta Martinelli; Claudio Pisano; Paolo Carminati; Nives Carenini; Giovanni Luca Beretta; Paola Perego; Michelandrea De Cesare; Graziella Pratesi; Franco Zunino
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity.
Journal of medicinal chemistry 2001;44(20):3264-74.
2001: Paola Perego; Michelandrea De Cesare; P De Isabella; Nives Carenini; Gino Beggiolin; Gabriella Pezzoni; Manlio Palumbo; L Tartaglia; Graziella Pratesi; Claudio Pisano; Paolo Carminati; G L Scheffer; Franco Zunino
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.
Cancer research 2001;61(16):6034-7.
2001: Mario Bigioni; Carmela Salvatore; A Bullo; daniela bellarosa; Elisabetta Iafrate; Fabio Animati; Giovanni Capranico; Cristina Goso; Carlo Alberto Maggi; Graziella Pratesi; Franco Zunino; Stefano Manzini
A comparative study of cellular and molecular pharmacology of doxorubicin and MEN 10755, a disaccharide analogue.
Biochemical pharmacology 2001;62(1):63-70.
2001: Giuliana Cassinelli; Rosanna Supino; Paola Perego; D Polizzi; Cinzia Lanzi; Graziella Pratesi; Franco Zunino
A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes.
International journal of cancer. Journal international du cancer 2001;92(5):738-47.
2001: Franco Zunino; Graziella Pratesi; Paola Perego
Role of the sugar moiety in the pharmacological activity of anthracyclines: development of a novel series of disaccharide analogs.
Biochemical pharmacology 2001;61(8):933-8.
2001: Roberta M Moretti; Marina Montagnani Marelli; Marcella Motta; D Polizzi; SV Monestiroli; Graziella Pratesi; Patrizia Limonta
Activation of the orphan nuclear receptor RORalpha induces growth arrest in androgen-independent DU 145 prostate cancer cells.
The Prostate 2001;46(4):327-35.
2001: Graziella Pratesi; Paola Perego; Franco Zunino
Role of Bcl-2 and its post-transcriptional modification in response to antitumor therapy.
Biochemical pharmacology 2001;61(4):381-6.
2001: Sabrina Dallavalle; A Ferrari; Lucio Merlini; Sergio Penco; Nives Carenini; Michelandrea De Cesare; Paola Perego; Graziella Pratesi; Franco Zunino
Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.
Bioorganic & medicinal chemistry letters 2001;11(3):291-4.
2001: O Gonzalez-Paz; D Polizzi; Michelandrea De Cesare; Franco Zunino; Mario Bigioni; Carlo Alberto Maggi; Stefano Manzini; Graziella Pratesi
Tissue distribution, antitumour activity and in vivo apoptosis induction by MEN10755 in nude mice.
European journal of cancer (Oxford, England : 1990) 2001;37(3):431-7.
2001: Rosanna Supino; D Polizzi; R Pavesi; Graziella Pratesi; F Guano; Giovanni Capranico; Manlio Palumbo; Claudia Sissi; S Richter; Gino Beggiolin; Ernesto Menta; Gabriella Pezzoni; S Spinelli; D Torriani; Nives Carenini; Laura Dal Bo; F Facchinetti; Monica Tortoreto; Franco Zunino
A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts.
Oncology 2001;61(3):234-42.
2001: Paola Perego; Elisabetta Corna; Michelandrea De Cesare; Laura Gatti; D Polizzi; Graziella Pratesi; Rosanna Supino; Franco Zunino
Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines.
Current medicinal chemistry 2001;8(1):31-7.
2001: Graziella Pratesi; SV Monestiroli
Preclinical evaluation of new anthracyclines.
Current medicinal chemistry 2001;8(1):9-13.
2000: Sabrina Dallavalle; T Delsoldato; A Ferrari; Lucio Merlini; Sergio Penco; Nives Carenini; Paola Perego; Michelandrea De Cesare; Graziella Pratesi; Franco Zunino
Novel 7-substituted camptothecins with potent antitumor activity.
Journal of medicinal chemistry 2000;43(21):3963-9.
2000: Michelandrea De Cesare; Franco Zunino; S Pace; Claudio Pisano; Graziella Pratesi
Efficacy and toxicity profile of oral topotecan in a panel of human tumour xenografts.
European journal of cancer (Oxford, England : 1990) 2000;36(12):1558-64.
2000: Carla Manzotti; Graziella Pratesi; Ernesto Menta; R Di Domenico; Ennio Cavalletti; H H Fiebig; Lloyd R Kelland; Nicholas Farrell; D Polizzi; Rosanna Supino; Gabriella Pezzoni; Franco Zunino
BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2626-34.
2000: Graziella Pratesi; D Polizzi; Paola Perego; Laura Dal Bo; Franco Zunino
Bcl-2 phosphorylation in a human breast carcinoma xenograft: a common event in response to effective DNA-damaging drugs.
Biochemical pharmacology 2000;60(1):77-82.
2000: Giuliana Cassinelli; Cinzia Lanzi; T Pensa; RA Gambetta; Gianluca Nasini; Giuditta Cuccuru; M Cassinis; Graziella Pratesi; D Polizzi; Monica Tortoreto; Franco Zunino
Clavilactones, a novel class of tyrosine kinase inhibitors of fungal origin.
Biochemical pharmacology 2000;59(12):1539-47.
2000: D Polizzi; Graziella Pratesi; SV Monestiroli; Monica Tortoreto; Franco Zunino; Ezio Bombardelli; Antonella Riva; Paolo Morazzoni; Tina Colombo; Maurizio D'Incalci; Massimo Zucchetti
Oral efficacy and bioavailability of a novel taxane.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):2070-4.
2000: Graziella Pratesi; Michelandrea De Cesare; Franco Zunino
Improvement of therapeutic index of low-dose topotecan delivered per os.
Annals of the New York Academy of Sciences 2000;922():330-3.
1999: Graziella Pratesi; Monica Tortoreto
Human tumor xenografts in nude mice are not always of human origin. A warning signal.
Cancer 1999;86(5):898-900.
1999: Graziella Pratesi; Paola Perego; D Polizzi; Sabina C Righetti; Rosanna Supino; C Caserini; Carla Manzotti; FC Giuliani; Gabriella Pezzoni; S Tognella; S Spinelli; Nicholas Farrell; Franco Zunino
A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts.
British journal of cancer 1999;80(12):1912-9.
1999: FM Arcamone; Fabio Animati; Mario Bigioni; Giovanni Capranico; C Caserini; A Cipollone; Michelandrea De Cesare; A Ettorre; F Guano; Stefano Manzini; ES Monteagudo; Graziella Pratesi; Carmela Salvatore; Rosanna Supino; Franco Zunino
Configurational requirements of the sugar moiety for the pharmacological activity of anthracycline disaccharides.
Biochemical pharmacology 1999;57(10):1133-9.
1999: D Polizzi; Graziella Pratesi; Monica Tortoreto; Rosanna Supino; Antonella Riva; Ezio Bombardelli; Franco Zunino
A novel taxane with improved tolerability and therapeutic activity in a panel of human tumor xenografts.
Cancer research 1999;59(5):1036-40.
1998: Graziella Pratesi; Michelandrea De Cesare; C Caserini; Paola Perego; Laura Dal Bo; D Polizzi; Rosanna Supino; Mario Bigioni; Stefano Manzini; Elisabetta Iafrate; Carmela Salvatore; A Casazza; FM Arcamone; Franco Zunino
Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2833-9.
1998: Patrizia Limonta; Graziella Pratesi; R M Moretti; Marina Montagnani Marelli; Marcella Motta; Donatella Dondi
Comments on inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist Cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II, Jungwirth et al., Eur J Cancer 1997, 33(7), 1141-1148.
European journal of cancer (Oxford, England : 1990) 1998;34(7):1134-6.
1998: Donatella Dondi; Roberta M Moretti; Marina Montagnani Marelli; Graziella Pratesi; D Polizzi; M Milani; Marcella Motta; Patrizia Limonta
Growth-inhibitory effects of luteinizing hormone-releasing hormone (LHRH) agonists on xenografts of the DU 145 human androgen-independent prostate cancer cell line in nude mice.
International journal of cancer. Journal international du cancer 1998;76(4):506-11.
1998: S Romanelli; Paola Perego; Graziella Pratesi; Nives Carenini; Monica Tortoreto; Franco Zunino
In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems.
Cancer chemotherapy and pharmacology 1998;41(5):385-90.
1998: Michelandrea De Cesare; Graziella Pratesi; A Giusti; D Polizzi; Franco Zunino
Stimulation of the apoptotic response as a basis for the therapeutic synergism of lonidamine and cisplatin in combination in human tumour xenografts.
British journal of cancer 1998;77(3):434-9.
1997: Franco Zunino; Paola Perego; S Pilotti; Graziella Pratesi; Rosanna Supino; FM Arcamone
Role of apoptotic response in cellular resistance to cytotoxic agents.
Pharmacology & therapeutics 1997;76(1-3):177-85.
1997: FM Arcamone; Fabio Animati; Giovanni Capranico; Paolo Lombardi; Graziella Pratesi; Stefano Manzini; Rosanna Supino; Franco Zunino
New developments in antitumor anthracyclines.
Pharmacology & therapeutics 1997;76(1-3):117-24.
1997: Mario Bigioni; Carmela Salvatore; Carla Palma; Stefano Manzini; Fabio Animati; Paolo Lombardi; Graziella Pratesi; Rosanna Supino; Franco Zunino
Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin.
Anti-cancer drugs 1997;8(9):845-52.
1997: Cinzia Lanzi; T Pensa; M Cassinis; C Corti; RA Gambetta; Graziella Pratesi; Ernesto Menta; E Ardini; Franco Zunino
A cell and mechanism-based approach for the selection of EGF receptor inhibitors.
Anti-cancer drug design 1997;12(6):515-24.
1997: FM Arcamone; Fabio Animati; M Berettoni; Mario Bigioni; Giovanni Capranico; A M Casazza; C Caserini; A Cipollone; Michelandrea De Cesare; M Franciotti; Paolo Lombardi; Andrea Madami; Stefano Manzini; ES Monteagudo; D Polizzi; Graziella Pratesi; Sabina C Righetti; Carmela Salvatore; Rosanna Supino; Franco Zunino
Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo.
Journal of the National Cancer Institute 1997;89(16):1217-23.
1997: C Caserini; Graziella Pratesi; Monica Tortoreto; B Bedogné; Nives Carenini; Rosanna Supino; Paola Perego; Sabina C Righetti; Franco Zunino
Apoptosis as a determinant of tumor sensitivity to topotecan in human ovarian tumors: preclinical in vitro/in vivo studies.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(6):955-61.
1996: Graziella Pratesi; S Cervi; A Balsari; G Bondiolotti; Lucia Maria Vicentini
Effect of serotonin and nicotine on the growth of a human small cell lung cancer xenograft.
Anticancer research 1996;16(6B):3615-9.
1996: Fabio Animati; FM Arcamone; Mario Bigioni; Giovanni Capranico; C Caserini; Michelandrea De Cesare; Paolo Lombardi; Graziella Pratesi; Carmela Salvatore; Rosanna Supino; Franco Zunino
Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochemistry and conformation.
Molecular pharmacology 1996;50(3):603-9.
1996: Graziella Pratesi; Michelandrea De Cesare; Franco Zunino
Efficacy of lonidamine combined with different DNA-damaging agents in the treatment of the MX-1 tumor xenograft.
Cancer chemotherapy and pharmacology 1996;38(2):123-8.
1996: C Corti; Graziella Pratesi; M DeCesare; R Pellegrini; R Giardini; R Supino; Franco Zunino
Spontaneous lung metastases in a human lung tumor xenograft: a new experimental model.
Journal of cancer research and clinical oncology 1996;122(3):154-60.
1995: Graziella Pratesi; Monica Tortoreto; C Corti; R Giardini; Franco Zunino
Successful local regional therapy with topotecan of intraperitoneally growing human ovarian carcinoma xenografts.
British journal of cancer 1995;71(3):525-8.
1994: Michelandrea De Cesare; Graziella Pratesi; Filippo de Braud; Franco Zunino; C G Stampino
Remarkable antitumor activity of 5'-deoxy-5-fluorouridine in human colorectal tumor xenografts.
Anticancer research 1994;14(2A):549-54.
1993: Carla Manzotti; R A Audisio; Graziella Pratesi
Importance of orthotopic implantation for human tumors as model systems: relevance to metastasis and invasion.
Clinical & experimental metastasis 1993;11(1):5-14.
1992: Franco Zunino; Giovanni Capranico; Graziella Pratesi; S Spinelli
Current approaches to new drug development in cancer chemotherapy.
Farmaco (Società chimica italiana : 1989) 1992;47(9):1115-32.
1991: R Demicheli; Graziella Pratesi; Roberto Foroni
The exponential-Gompertzian tumor growth model: data from six tumor cell lines in vitro and in vivo. Estimate of the transition point from exponential to Gompertzian growth and potential clinical implications.
Tumori 1991;77(3):189-95.
1991: Graziella Pratesi; Carla Manzotti; Monica Tortoreto; R A Audisio; Franco Zunino
Differential efficacy of flavone acetic against liver versus lung metastases in a human tumour xenograft.
British journal of cancer 1991;63(1):71-4.
1990: Franco Zunino; Graziella Pratesi; Franca Formelli; A Pasini
Evaluation of a platinum-doxorubicin complex in experimental tumor systems.
Investigational new drugs 1990;8(4):341-5.
1990: C Soranzo; Graziella Pratesi; Franco Zunino
Different interaction of cisplatin and etoposide on in vivo and in vitro tumor systems.
Anti-cancer drugs 1990;1(1):23-8.
1989: S Gianì; V Bedini; I Cataldo; Elisabetta Iafrate; S Martignone; Sylvie Ménard; S Pilotti; Graziella Pratesi; E Soresi; MI Colnaghi
In vivo and in vitro growth of SCLC cells derived from biopsies.
Tumori 1989;75(6):570-5.
1989: R Demicheli; Roberto Foroni; A Ingrosso; Graziella Pratesi; C Soranzo; Monica Tortoreto
An exponential-Gompertzian description of LoVo cell tumor growth from in vivo and in vitro data.
Cancer research 1989;49(23):6543-6.
1989: R Demicheli; Graziella Pratesi; Roberto Foroni; M G Barbagini; Monica Tortoreto
Relative role of host and tumor in the growth pattern of murine and human neoplasms following subcutaneous transplantation in mice.
Tumori 1989;75(5):429-34.
1989: C Soranzo; A Ingrosso; Graziella Pratesi; L Lombardi; S Pilotti; Franco Zunino
Malignant transformation of host cells by a human small cell lung cancer xenografted into nude mice.
Anticancer research 1989;9(2):361-6.
1989: Graziella Pratesi; Carla Manzotti; Monica Tortoreto; E Prosperi; Franco Zunino
Effects of 5-FU and cis-DDP combination on human colorectal tumor xenografts.
Tumori 1989;75(1):60-5.
1989: Franco Zunino; Graziella Pratesi; A Micheloni; Ennio Cavalletti; F Sala; O Tofanetti
Protective effect of reduced glutathione against cisplatin-induced renal and systemic toxicity and its influence on the therapeutic activity of the antitumor drug.
Chemico-biological interactions 1989;70(1-2):89-101.
1989: Graziella Pratesi; G Savi
Effects of tauromustine, a water-soluble nitrosourea compound on NMU-1 murine lung tumor.
Oncology 1989;46(2):132-5.
1988: Graziella Pratesi; Carla Manzotti; G Damia; M D'Incalci
Response of chemically induced primary colon tumours of the mouse to flavone acetic acid (NSC 347 512).
British journal of cancer 1988;58(2):144-6.
1988: Graziella Pratesi; Luca Gianni; Carla Manzotti; Franco Zunino
Sequence dependence of the antitumor and toxic effects of 5-fluorouracil and cis-diamminedichloroplatinum combination on primary colon tumors in mice.
Cancer chemotherapy and pharmacology 1988;21(3):237-40.
1987: Franco Zunino; Graziella Pratesi; Gabriella Pezzoni
Increased therapeutic efficacy and reduced toxicity of doxorubicin linked to pyran copolymer via the side chain of the drug.
Cancer treatment reports 1987;71(4):367-73.
1986: Graziella Pratesi; Gabriella Pezzoni; R Giardini; R Doci; M Valente; G Parmiani
Growth characteristics of human colorectal and non-small cell lung tumors xenografted into nude mice: possible correlation with prognosis.
Tumori 1986;72(4):351-6.
1985: Graziella Pratesi; G Savi; Gabriella Pezzoni; O Bellini; S Penco; S Tinelli; Franco Zunino
Poly-L-aspartic acid as a carrier for doxorubicin: a comparative in vivo study of free and polymer-bound drug.
British journal of cancer 1985;52(6):841-8.
1985: Graziella Pratesi; Gabriella Pezzoni; G Parmiani
NMU-1, a new transplantable mouse lung tumor: biological and chemosensitivity properties in vivo.
Cancer treatment reports 1985;69(2):219-21.
1985: O Tofanetti; Ennio Cavalletti; A Besati; Graziella Pratesi; Gabriella Pezzoni; Franco Zunino
Prevention of cyclophosphamide-induced urotoxicity by reduced glutathione and its effect on acute toxicity and antitumor activity of the alkylating agent.
Cancer chemotherapy and pharmacology 1985;14(3):188-93.
1983: S Penco; A M Casazza; G Franchi; B Barbieri; O Bellini; A Podestà; G Savi; Graziella Pratesi; Cristina Geroni; A Di Marco; FM Arcamone
Synthesis, antitumor activity, and cardiac toxicity of new 4-demethoxyanthracyclines.
Cancer treatment reports 1983;67(7-8):665-73.
1983: A M Casazza; G Savi; Graziella Pratesi; A Di Marco
Antitumor activity in mice of 4'-deoxydoxorubicin in comparison with doxorubicin.
European journal of cancer & clinical oncology 1983;19(3):411-8.
1983: A Bargiotti; A M Casazza; G Cassinelli; A Di Marco; S Penco; Graziella Pratesi; Rosanna Supino; A Zaccara; Franco Zunino; FM Arcamone
Synthesis, biological and biochemical properties of new anthracyclines modified in the aminosugar moiety.
Cancer chemotherapy and pharmacology 1983;10(2):84-9.
1982: G Cassinelli; G Rivola; D Ruggieri; FM Arcamone; A Grein; S Merli; C Spalla; A M Casazza; A Di Marco; Graziella Pratesi
New anthracycline glycosides: 4-O-demethyl-11-deoxydoxorubicin and analogues from Streptomyces peucetius var. aureus.
The Journal of antibiotics 1982;35(2):176-83.
1981: Franco Zunino; A M Casazza; Graziella Pratesi; F Formelli; A DiMarco
Effect of the methylation of aglycone hydroxyl groups on the biological and biochemical properties of daunorubicin.
Biochemical pharmacology 1981;30(13):1856-8.
1981: A Di Marco; T Skovsgaard; A M Casazza; Graziella Pratesi; N I Nissen; K Danø
Cross resistance and cellular uptake of 4'-O-methyldoxorubicin in experimental tumors with acquired resistance to doxorubicin.
Cancer chemotherapy and pharmacology 1981;7(1):15-20.
1980: G Cassinelli; F Di Matteo; S Forenza; M C Ripamonti; G Rivola; FM Arcamone; A Di Marco; A M Casazza; C Soranzo; Graziella Pratesi
New anthracycline glycosides from Micromonospora. II. isolation, characterization and biological properties.
The Journal of antibiotics 1980;33(12):1468-73.
1980: A M Casazza; Graziella Pratesi; FC Giuliani; A Di Marco
Antileukemic activity of 4-demethoxydaunorubicin in mice.
Tumori 1980;66(5):549-64.

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