FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

William Pratt

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Phenomena

Protein Binding

Concepts & Ideas

Co-author Network

Publications

TOP 3
Adrienne M Wang; Jason P Chua; Catherine A Collins; Jason E Gestwicki; Susan Klinedinst; Tomoko Komiyama; Xiaokai Li; Diane E Merry; Yoshinari Miyata; Yoshihiro Morishima; Yoichi Osawa; Hwei-Ming Peng; William B Pratt; Andrew P Lieberman
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.
Aarif Ahsan; Christopher Gouveia; Susan M Hiniker; Shruti Jolly; Theodore S Lawrence; William B Pratt; Susmita G Ramanand; Dipankar Ray; Alnawaz Rehemtulla; Kristy Truong; Carter Van Waes; Christopher Whitehead; Mukesh K Nyati
Wild-type EGFR is stabilized by direct interaction with HSP90 in cancer cells and tumors.
Yoshihiro Morishima; Jason E Gestwicki; Miranda Lau; Yoshinari Miyata; Hwei-Ming Peng; William B Pratt; Yoichi Osawa
Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of William Pratt (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Adrienne M Wang; Jason P Chua; Catherine A Collins; Jason E Gestwicki; Susan Klinedinst; Tomoko Komiyama; Xiaokai Li; Diane E Merry; Yoshinari Miyata; Yoshihiro Morishima; Yoichi Osawa; Hwei-Ming Peng; William B Pratt; Andrew P Lieberman
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.
Nature chemical biology 2013;9(2):112-8.
2012: Aarif Ahsan; Christopher Gouveia; Susan M Hiniker; Shruti Jolly; Theodore S Lawrence; William B Pratt; Susmita G Ramanand; Dipankar Ray; Alnawaz Rehemtulla; Kristy Truong; Carter Van Waes; Christopher Whitehead; Mukesh K Nyati
Wild-type EGFR is stabilized by direct interaction with HSP90 in cancer cells and tumors.
Neoplasia (New York, N.Y.) 2012;14(8):670-7.
2011: Yoshihiro Morishima; Jason E Gestwicki; Miranda Lau; Yoshinari Miyata; Hwei-Ming Peng; William B Pratt; Yoichi Osawa
Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft.
Biochemistry 2011;50(33):7146-56.
2010: Kelly M Clapp; Hwei-Ming Peng; Yoshihiro Morishima; Miranda Lau; Vyvyca J Walker; William B Pratt; Yoichi Osawa
C331A mutant of neuronal nitric-oxide synthase is labilized for Hsp70/CHIP (C terminus of HSC70-interacting protein)-dependent ubiquitination.
The Journal of biological chemistry 2010;285(44):33642-51.
2010: Adrienne M Wang; Yoshihiro Morishima; Kelly M Clapp; Hwei-Ming Peng; William B Pratt; Jason E Gestwicki; Yoichi Osawa; Andrew P Lieberman
Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation.
The Journal of biological chemistry 2010;285(21):15714-23.
2010: William B Pratt; Yoshihiro Morishima; Hwei-Ming Peng; Yoichi Osawa
Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage.
Experimental biology and medicine (Maywood, N.J.) 2010;235(3):278-89.
2009: Hwei-Ming Peng; Yoshihiro Morishima; Kelly M Clapp; Miranda Lau; William B Pratt; Yoichi Osawa
Dynamic cycling with Hsp90 stabilizes neuronal nitric oxide synthase through calmodulin-dependent inhibition of ubiquitination.
Biochemistry 2009;48(35):8483-90.
2008: Yoshihiro Morishima; Adrienne M Wang; Zhigang Yu; William B Pratt; Yoichi Osawa; Andrew P Lieberman
CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins.
Human molecular genetics 2008;17(24):3942-52.
2008: William B Pratt; Yoshihiro Morishima; Yoichi Osawa
The Hsp90 chaperone machinery regulates signaling by modulating ligand binding clefts.
The Journal of biological chemistry 2008;283(34):22885-9.
2006: Monzy Thomas; Jennifer M Harrell; Yoshihiro Morishima; Hwei-Ming Peng; William B Pratt; Andrew P Lieberman
Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction.
Human molecular genetics 2006;15(11):1876-83.
2006: William B Pratt; Yoshihiro Morishima; M Murphy; M Harrell
Chaperoning of glucocorticoid receptors.
Handbook of experimental pharmacology 2006;(172):111-38.
2005: Yoshihiro Morishima; Hwei-Ming Peng; Hsia-lien Lin; Paul Hollenberg; Roger K Sunahara; Yoichi Osawa; William B Pratt
Regulation of cytochrome P450 2E1 by heat shock protein 90-dependent stabilization and CHIP-dependent proteasomal degradation.
Biochemistry 2005;44(49):16333-40.
2005: Patrick J M Murphy; Yoshihiro Morishima; Jeffrey J Kovacs; Tso-Pang Yao; William B Pratt
Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone.
The Journal of biological chemistry 2005;280(40):33792-9.
2005: Jeffrey J Kovacs; Patrick J M Murphy; Stéphanie Gaillard; Xuan Zhao; June-Tai Wu; Christopher V Nicchitta; Minoru Yoshida; David O Toft; William B Pratt; Tso-Pang Yao
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
Molecular cell 2005;18(5):601-7.
2004: Mario D Galigniana; Yoshihiro Morishima; Philippe A Gallay; William B Pratt
Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex.
The Journal of biological chemistry 2004;279(53):55754-9.
2004: Jennifer M Harrell; Patrick J M Murphy; Yoshihiro Morishima; Haifeng Chen; John F Mansfield; Mario D Galigniana; William B Pratt
Evidence for glucocorticoid receptor transport on microtubules by dynein.
The Journal of biological chemistry 2004;279(52):54647-54.
2004: Hwei-Ming Peng; Yoshihiro Morishima; Gary J Jenkins; Anwar Y Dunbar; Miranda Lau; Winston Patterson; William B Pratt; Yoichi Osawa
Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase.
The Journal of biological chemistry 2004;279(51):52970-7.
2004: William B Pratt; Mario D Galigniana; Jennifer M Harrell; Donald B DeFranco
Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement.
Cellular signalling 2004;16(8):857-72.
2004: Scott S Billecke; Dragomir I Draganov; Yoshihiro Morishima; Patrick J M Murphy; Anwar Y Dunbar; William B Pratt; Yoichi Osawa
The role of hsp90 in heme-dependent activation of apo-neuronal nitric-oxide synthase.
The Journal of biological chemistry 2004;279(29):30252-8.
2004: Patrick J M Murphy; Mario D Galigniana; Yoshihiro Morishima; Jennifer M Harrell; Roland P S Kwok; Mats Ljungman; William B Pratt
Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.
The Journal of biological chemistry 2004;279(29):30195-201.
2004: Mario D Galigniana; Jennifer M Harrell; Heather M O'Hagen; Mats Ljungman; William B Pratt
Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.
The Journal of biological chemistry 2004;279(21):22483-9.
2004: Nashaat Gerges; Irwin C Tran; Donald S Backos; Jennifer M Harrell; Michael Chinkers; William B Pratt; Jose A Esteban
Independent functions of hsp90 in neurotransmitter release and in the continuous synaptic cycling of AMPA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(20):4758-66.
2004: Mario D Galigniana; Jennifer M Harrell; Paul R Housley; Winston Patterson; Stephen K Fisher; William B Pratt
Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation.
Brain research. Molecular brain research 2004;123(1-2):27-36.
2004: Monzy Thomas; Nahid Dadgar; Abhishek Aphale; Jennifer M Harrell; Robin Kunkel; William B Pratt; Andrew P Lieberman
Androgen receptor acetylation site mutations cause trafficking defects, misfolding, and aggregation similar to expanded glutamine tracts.
The Journal of biological chemistry 2004;279(9):8389-95.
2004: William B Pratt; Mario D Galigniana; Yoshihiro Morishima; Patrick J M Murphy
Role of molecular chaperones in steroid receptor action.
Essays in biochemistry 2004;40():41-58.
2003: Yoshihiro Morishima; Kimon C Kanelakis; Patrick J M Murphy; Ezra R Lowe; Gary J Jenkins; Yoichi Osawa; Roger K Sunahara; William B Pratt
The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex.
The Journal of biological chemistry 2003;278(49):48754-63.
2003: Patrick J M Murphy; Yoshihiro Morishima; Haifeng Chen; Mario D Galigniana; John F Mansfield; S Stoney Simons; William B Pratt
Visualization and mechanism of assembly of a glucocorticoid receptor.Hsp70 complex that is primed for subsequent Hsp90-dependent opening of the steroid binding cleft.
The Journal of biological chemistry 2003;278(37):34764-73.
2003: William B Pratt; David O Toft
Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery.
Experimental biology and medicine (Maywood, N.J.) 2003;228(2):111-33.
2003: Kimon C Kanelakis; William B Pratt
Regulation of glucocorticoid receptor ligand-binding activity by the hsp90/hsp70-based chaperone machinery.
Methods in enzymology 2003;364():159-73.
2002: Mario D Galigniana; Jennifer M Harrell; Patrick J M Murphy; Michael Chinkers; Christine Radanyi; Jack-Michel Renoir; Mingjie Zhang; William B Pratt
Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain.
Biochemistry 2002;41(46):13602-10.
2002: Sunil Kaul; Patrick J M Murphy; Jun Chen; Lloyd Brown; William B Pratt; S Stoney Simons
Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain.
The Journal of biological chemistry 2002;277(39):36223-32.
2002: Kimon C Kanelakis; Donna S Shewach; William B Pratt
Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly.
The Journal of biological chemistry 2002;277(37):33698-703.
2002: Scott S Billecke; Andrew T Bender; Kimon C Kanelakis; Patrick J M Murphy; Ezra R Lowe; Yasuhiko Kamada; William B Pratt; Yoichi Osawa
hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any action of hsp90.
The Journal of biological chemistry 2002;277(23):20504-9.
2002: Jennifer M Harrell; Isaac Kurek; Adina Breiman; Christine Radanyi; Jack-Michel Renoir; William B Pratt; Mario D Galigniana
All of the protein interactions that link steroid receptor.hsp90.immunophilin heterocomplexes to cytoplasmic dynein are common to plant and animal cells.
Biochemistry 2002;41(17):5581-7.
2001: Yanwen Guo; Toumy Guettouche; Mary Fenna; Frank Boellmann; William B Pratt; David O Toft; David Smith; Richard Voellmy
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex.
The Journal of biological chemistry 2001;276(49):45791-9.
2001: Hani Houshyar; Mario D Galigniana; William B Pratt; James H Woods
Differential responsivity of the hypothalamic-pituitary-adrenal axis to glucocorticoid negative-feedback and corticotropin releasing hormone in rats undergoing morphine withdrawal: possible mechanisms involved in facilitated and attenuated stress responses.
Journal of neuroendocrinology 2001;13(10):875-86.
2001: Patrick J M Murphy; Kimon C Kanelakis; Mario D Galigniana; Yoshihiro Morishima; William B Pratt
Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate.
The Journal of biological chemistry 2001;276(32):30092-8.
2001: Mario D Galigniana; Christine Radanyi; Jack-Michel Renoir; Paul R Housley; William B Pratt
Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus.
The Journal of biological chemistry 2001;276(18):14884-9.
2001: William B Pratt; P Krishna; Laura J Olsen
Hsp90-binding immunophilins in plants: the protein movers.
Trends in plant science 2001;6(2):54-8.
2001: Yoshihiro Morishima; Kimon C Kanelakis; Patrick J M Murphy; Donna S Shewach; William B Pratt
Evidence for iterative ratcheting of receptor-bound hsp70 between its ATP and ADP conformations during assembly of glucocorticoid receptor.hsp90 heterocomplexes.
Biochemistry 2001;40(4):1109-16.
2000: Kimon C Kanelakis; Patrick J M Murphy; Mario D Galigniana; Yoshihiro Morishima; S Takayama; J C Reed; David O Toft; William B Pratt
hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1.
Biochemistry 2000;39(46):14314-21.
2000: Yoshihiro Morishima; Patrick J M Murphy; D P Li; Edwin Ramon Sanchez; William B Pratt
Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket.
The Journal of biological chemistry 2000;275(24):18054-60.
2000: Yoshihiro Morishima; Kimon C Kanelakis; AM Silverstein; KD Dittmar; Lourdes Estrada; William B Pratt
The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system.
The Journal of biological chemistry 2000;275(10):6894-900.
1999: AM Silverstein; Mario D Galigniana; Kimon C Kanelakis; Christine Radanyi; Jack-Michel Renoir; William B Pratt
Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein.
The Journal of biological chemistry 1999;274(52):36980-6.
1999: G Giannoukos; A M Silverstein; William B Pratt; S Stoney Simons
The seven amino acids (547-553) of rat glucocorticoid receptor required for steroid and hsp90 binding contain a functionally independent LXXLL motif that is critical for steroid binding.
The Journal of biological chemistry 1999;274(51):36527-36.
1999: William B Pratt; AM Silverstein; Mario D Galigniana
A model for the cytoplasmic trafficking of signalling proteins involving the hsp90-binding immunophilins and p50cdc37.
Cellular signalling 1999;11(12):839-51.
1999: Kimon C Kanelakis; Yoshihiro Morishima; KD Dittmar; Mario D Galigniana; S Takayama; J C Reed; William B Pratt
Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery.
The Journal of biological chemistry 1999;274(48):34134-40.
1999: Mario D Galigniana; Paul R Housley; D B DeFranco; William B Pratt
Inhibition of glucocorticoid receptor nucleocytoplasmic shuttling by okadaic acid requires intact cytoskeleton.
The Journal of biological chemistry 1999;274(23):16222-7.
1999: Andrew T Bender; AM Silverstein; Damon R Demady; Kimon C Kanelakis; S Noguchi; William B Pratt; Yoichi Osawa
Neuronal nitric-oxide synthase is regulated by the Hsp90-based chaperone system in vivo.
The Journal of biological chemistry 1999;274(3):1472-8.
1998: Mario D Galigniana; J L Scruggs; James Herrington; Michael J Welsh; Christin Carter-Su; Paul R Housley; William B Pratt
Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton.
Molecular endocrinology (Baltimore, Md.) 1998;12(12):1903-13.
1998: Claudio Alejandro Caamano; M Inés Morano; F C Dalman; William B Pratt; Huda Akil
A conserved proline in the hsp90 binding region of the glucocorticoid receptor is required for hsp90 heterocomplex stabilization and receptor signaling.
The Journal of biological chemistry 1998;273(32):20473-80.
1998: AM Silverstein; Nicholas Grammatikakis; Brent H Cochran; Michael Chinkers; William B Pratt
p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site.
The Journal of biological chemistry 1998;273(32):20090-5.
1998: William B Pratt; KD Dittmar
Studies with Purified Chaperones Advance the Understanding of the Mechanism of Glucocorticoid Receptor-hsp90 Heterocomplex Assembly.
Trends in endocrinology and metabolism: TEM 1998;9(6):244-52.
1998: M Xu; KD Dittmar; G Giannoukos; William B Pratt; S Stoney Simons
Binding of hsp90 to the glucocorticoid receptor requires a specific 7-amino acid sequence at the amino terminus of the hormone-binding domain.
The Journal of biological chemistry 1998;273(22):13918-24.
1998: William B Pratt
The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1998;217(4):420-34.
1998: KD Dittmar; M Banach; Mario D Galigniana; William B Pratt
The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.
The Journal of biological chemistry 1998;273(13):7358-66.
1997: KD Dittmar; Damon R Demady; L F Stancato; P Krishna; William B Pratt
Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.
The Journal of biological chemistry 1997;272(34):21213-20.
1997: AM Silverstein; Mario D Galigniana; M S Chen; J K Owens-Grillo; Michael Chinkers; William B Pratt
Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin.
The Journal of biological chemistry 1997;272(26):16224-30.
1997: Michael J Czar; Mario D Galigniana; AM Silverstein; William B Pratt
Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus.
Biochemistry 1997;36(25):7776-85.
1997: William B Pratt; David O Toft
Steroid receptor interactions with heat shock protein and immunophilin chaperones.
Endocrine reviews 1997;18(3):306-60.
1997: KD Dittmar; William B Pratt
Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation.
The Journal of biological chemistry 1997;272(20):13047-54.
1997: L F Stancato; AM Silverstein; J K Owens-Grillo; Y H Chow; Richard Jove; William B Pratt
The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase.
The Journal of biological chemistry 1997;272(7):4013-20.
1997: William B Pratt
The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase.
Annual review of pharmacology and toxicology 1997;37():297-326.
1996: M S Chen; AM Silverstein; William B Pratt; Michael Chinkers
The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant.
The Journal of biological chemistry 1996;271(50):32315-20.
1996: J K Owens-Grillo; LF Stancato; K Hoffmann; William B Pratt; P Krishna
Binding of immunophilins to the 90 kDa heat shock protein (hsp90) via a tetratricopeptide repeat domain is a conserved protein interaction in plants.
Biochemistry 1996;35(48):15249-55.
1996: Michael J Czar; Michael J Welsh; William B Pratt
Immunofluorescence localization of the 90-kDa heat-shock protein to cytoskeleton.
European journal of cell biology 1996;70(4):322-30.
1996: M R Gralinski; S C Black; LF Stancato; Kenneth S Kilgore; P A Campau; James L Park; M J Ozeck; William B Pratt; Benedict R Lucchesi
Heat stress protects the perfused rabbit heart from complement-mediated injury.
The American journal of physiology 1996;271(2 Pt 2):H571-8.
1996: J K Owens-Grillo; Michael J Czar; K A Hutchison; K Hoffmann; G H Perdew; William B Pratt
A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains.
The Journal of biological chemistry 1996;271(23):13468-75.
1996: K A Hutchison; KD Dittmar; LF Stancato; William B Pratt
Ability of various members of the hsp70 family of chaperones to promote assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.
The Journal of steroid biochemistry and molecular biology 1996;58(3):251-8.
1996: KD Dittmar; K A Hutchison; J K Owens-Grillo; William B Pratt
Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.
The Journal of biological chemistry 1996;271(22):12833-9.
1996: LF Stancato; AM Silverstein; C Gitler; B Groner; William B Pratt
Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain.
The Journal of biological chemistry 1996;271(15):8831-6.
1996: LF Stancato; M David; Christin Carter-Su; Andrew C Larner; William B Pratt
Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation.
The Journal of biological chemistry 1996;271(8):4134-7.
1996: LF Stancato; K A Hutchison; P Krishna; William B Pratt
Animal and plant cell lysates share a conserved chaperone system that assembles the glucocorticoid receptor into a functional heterocomplex with hsp90.
Biochemistry 1996;35(2):554-61.
1996: William B Pratt; U Gehring; D O Toft
Molecular chaperoning of steroid hormone receptors.
EXS 1996;77():79-95.
1995: Michael J Czar; Robert H Lyons Jr; Michael J Welsh; Jack-Michel Renoir; William B Pratt
Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorticoid receptor from the cytoplasm to the nucleus.
Molecular endocrinology (Baltimore, Md.) 1995;9(11):1549-60.
1995: J K Owens-Grillo; K Hoffmann; K A Hutchison; Anthony W Yem; M R Deibel; R E Handschumacher; William B Pratt
The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor.
The Journal of biological chemistry 1995;270(35):20479-84.
1995: K A Hutchison; LF Stancato; J K Owens-Grillo; J L Johnson; P Krishna; D O Toft; William B Pratt
The 23-kDa acidic protein in reticulocyte lysate is the weakly bound component of the hsp foldosome that is required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.
The Journal of biological chemistry 1995;270(32):18841-7.
1995: Claudio Alejandro Caamano; M Inés Morano; F C Dalman; Mary T Hoversten; Stanley J Watson Jr; William B Pratt; Huda Akil
Point mutations in the 90-kDa heat shock protein binding region of the glucocorticoid receptor affect the functional characteristics of the receptor.
Annals of the New York Academy of Sciences 1995;761():403-4.
1995: S Stoney Simons; William B Pratt
Glucocorticoid receptor thiols and steroid-binding activity.
Methods in enzymology 1995;251():406-22.
1994: Michael J Czar; J K Owens-Grillo; Anthony W Yem; K L Leach; M R Deibel; Michael J Welsh; William B Pratt
The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor.
Molecular endocrinology (Baltimore, Md.) 1994;8(12):1731-41.
1994: Claudio Alejandro Caamano; M Inés Morano; Stanley J Watson Jr; F C Dalman; William B Pratt; Huda Akil
The functional relevance of the heteromeric structure of corticosteroid receptors.
Annals of the New York Academy of Sciences 1994;746():68-77; discussion 77-8, 131-3.
1994: K A Hutchison; KD Dittmar; William B Pratt
All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with heat shock protein 90 are preassociated in a self-sufficient protein folding structure, a "foldosome".
The Journal of biological chemistry 1994;269(45):27894-9.
1994: LF Stancato; Y H Chow; J K Owens-Grillo; Anthony W Yem; M R Deibel; Richard Jove; William B Pratt
The native v-Raf.hsp90.p50 heterocomplex contains a novel immunophilin of the FK506 binding class.
The Journal of biological chemistry 1994;269(35):22157-61.
1994: Michael J Czar; J K Owens-Grillo; KD Dittmar; K A Hutchison; A M Zacharek; K L Leach; M R Deibel; William B Pratt
Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex.
The Journal of biological chemistry 1994;269(15):11155-61.
1994: William B Pratt; Michael J Welsh
Chaperone functions of the heat shock proteins associated with steroid receptors.
Seminars in cell biology 1994;5(2):83-93.
1994: K A Hutchison; KD Dittmar; Michael J Czar; William B Pratt
Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90.
The Journal of biological chemistry 1994;269(7):5043-9.
1993: K A Hutchison; F C Dalman; W Hoeck; B Groner; William B Pratt
Localization of the approximately 12 kDa M(r) discrepancy in gel migration of the mouse glucocorticoid receptor to the major phosphorylated cyanogen bromide fragment in the transactivating domain.
The Journal of steroid biochemistry and molecular biology 1993;46(6):681-6.
1993: LF Stancato; Y H Chow; K A Hutchison; G H Perdew; Richard Jove; William B Pratt
Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system.
The Journal of biological chemistry 1993;268(29):21711-6.
1993: William B Pratt
The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor.
The Journal of biological chemistry 1993;268(29):21455-8.
1993: William B Pratt; Michael J Czar; LF Stancato; J K Owens
The hsp56 immunophilin component of steroid receptor heterocomplexes: could this be the elusive nuclear localization signal-binding protein?
The Journal of steroid biochemistry and molecular biology 1993;46(3):269-79.
1993: K A Hutchison; L C Scherrer; Michael J Czar; LF Stancato; Y H Chow; Richard Jove; William B Pratt
Regulation of glucocorticoid receptor function through assembly of a receptor-heat shock protein complex.
Annals of the New York Academy of Sciences 1993;684():35-48.
1993: L C Scherrer; D Picard; E Massa; Jeffrey M Harmon; S Stoney Simons; Keith R Yamamoto; William B Pratt
Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90.
Biochemistry 1993;32(20):5381-6.
1993: K A Hutchison; L C Scherrer; Michael J Czar; Y Ning; Edwin Ramon Sanchez; K L Leach; M R Deibel; William B Pratt
FK506 binding to the 56-kilodalton immunophilin (Hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function.
Biochemistry 1993;32(15):3953-7.
1993: LF Stancato; K A Hutchison; P K Chakraborti; S Stoney Simons; William B Pratt
Differential effects of the reversible thiol-reactive agents arsenite and methyl methanethiosulfonate on steroid binding by the glucocorticoid receptor.
Biochemistry 1993;32(14):3729-36.
1992: William B Pratt
Control of steroid receptor function and cytoplasmic-nuclear transport by heat shock proteins.
BioEssays : news and reviews in molecular, cellular and developmental biology 1992;14(12):841-8.
1992: L C Scherrer; William B Pratt
Energy-dependent conversion of transformed cytosolic glucocorticoid receptors from soluble to particulate-bound form.
Biochemistry 1992;31(44):10879-86.
1992: William B Pratt; K A Hutchison; L C Scherrer
Steroid receptor folding by heat-shock proteins and composition of the receptor heterocomplex.
Trends in endocrinology and metabolism: TEM 1992;3(9):326-33.
1992: L C Scherrer; K A Hutchison; Edwin Ramon Sanchez; S K Randall; William B Pratt
A heat shock protein complex isolated from rabbit reticulocyte lysate can reconstitute a functional glucocorticoid receptor-Hsp90 complex.
Biochemistry 1992;31(32):7325-9.
1992: K A Hutchison; Michael J Czar; L C Scherrer; William B Pratt
Monovalent cation selectivity for ATP-dependent association of the glucocorticoid receptor with hsp70 and hsp90.
The Journal of biological chemistry 1992;267(20):14047-53.
1992: K A Hutchison; LF Stancato; Richard Jove; William B Pratt
The protein-protein complex between pp60v-src and hsp90 is stabilized by molybdate, vanadate, tungstate, and an endogenous cytosolic metal.
The Journal of biological chemistry 1992;267(20):13952-7.
1992: L C Scherrer; William B Pratt
Association of the transformed glucocorticoid receptor with a cytoskeletal protein complex.
The Journal of steroid biochemistry and molecular biology 1992;41(3-8):719-21.
1992: K A Hutchison; G Matić; Michael J Czar; William B Pratt
DNA-binding and non-DNA-binding forms of the transformed glucocorticoid receptor.
The Journal of steroid biochemistry and molecular biology 1992;41(3-8):715-8.
1992: William B Pratt; L C Scherrer; K A Hutchison; F C Dalman
A model of glucocorticoid receptor unfolding and stabilization by a heat shock protein complex.
The Journal of steroid biochemistry and molecular biology 1992;41(3-8):223-9.
1992: K A Hutchison; Michael J Czar; William B Pratt
Evidence that the hormone-binding domain of the mouse glucocorticoid receptor directly represses DNA binding activity in a major portion of receptors that are "misfolded" after removal of hsp90.
The Journal of biological chemistry 1992;267(5):3190-5.
1992: K A Hutchison; B K Brott; J H De Leon; G H Perdew; Richard Jove; William B Pratt
Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system.
The Journal of biological chemistry 1992;267(5):2902-8.
1991: S Meshinchi; LF Stancato; B M Gordon; K W Jones; William B Pratt
Purification of the endogenous glucocorticoid receptor stabilizing factor.
Biochemistry 1991;30(35):8617-22.
1991: K A Hutchison; G Matić; S Meshinchi; E H Bresnick; William B Pratt
Redox manipulation of DNA binding activity and BuGR epitope reactivity of the glucocorticoid receptor.
The Journal of biological chemistry 1991;266(16):10505-9.
1991: F C Dalman; L J Sturzenbecker; A A Levin; D A Lucas; G H Perdew; M Petkovitch; P Chambon; J F Grippo; William B Pratt
Retinoic acid receptor belongs to a subclass of nuclear receptors that do not form "docking" complexes with hsp90.
Biochemistry 1991;30(22):5605-8.
1991: F C Dalman; L C Scherrer; Larry P Taylor; Huda Akil; William B Pratt
Localization of the 90-kDa heat shock protein-binding site within the hormone-binding domain of the glucocorticoid receptor by peptide competition.
The Journal of biological chemistry 1991;266(6):3482-90.
1991: Vilma Martins; William B Pratt; L Terracio; M A Hirst; G M Ringold; Paul R Housley
Demonstration by confocal microscopy that unliganded overexpressed glucocorticoid receptors are distributed in a nonrandom manner throughout all planes of the nucleus.
Molecular endocrinology (Baltimore, Md.) 1991;5(2):217-25.
1990: William B Pratt; F C Dalman; S Meshinchi; L C Scherrer
The relationship between glucocorticoid receptor binding to Hsp90 and receptor function.
Nihon Naibunpi Gakkai zasshi 1990;66(12):1185-97.
1990: L C Scherrer; F C Dalman; E Massa; S Meshinchi; William B Pratt
Structural and functional reconstitution of the glucocorticoid receptor-hsp90 complex.
The Journal of biological chemistry 1990;265(35):21397-400.
1990: Edwin Ramon Sanchez; M Hirst; L C Scherrer; H Y Tang; Michael J Welsh; Jeffrey M Harmon; S Stoney Simons; G M Ringold; William B Pratt
Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90.
The Journal of biological chemistry 1990;265(33):20123-30.
1990: William B Pratt
Interaction of hsp90 with steroid receptors: organizing some diverse observations and presenting the newest concepts.
Molecular and cellular endocrinology 1990;74(1):C69-76.
1990: Paul R Housley; Edwin Ramon Sanchez; M Danielsen; G M Ringold; William B Pratt
Evidence that the conserved region in the steroid binding domain of the glucocorticoid receptor is required for both optimal binding of hsp90 and protection from proteolytic cleavage. A two-site model for hsp90 binding to the steroid binding domain.
The Journal of biological chemistry 1990;265(22):12778-81.
1990: S Meshinchi; G Matić; K A Hutchison; William B Pratt
Selective molybdate-directed covalent modification of sulfhydryl groups in the steroid-binding versus the DNA-binding domain of the glucocorticoid receptor.
The Journal of biological chemistry 1990;265(20):11643-9.
1990: Edwin Ramon Sanchez; L E Faber; W J Henzel; William B Pratt
The 56-59-kilodalton protein identified in untransformed steroid receptor complexes is a unique protein that exists in cytosol in a complex with both the 70- and 90-kilodalton heat shock proteins.
Biochemistry 1990;29(21):5145-52.
1990: S Meshinchi; Edwin Ramon Sanchez; K J Martell; William B Pratt
Elimination and reconstitution of the requirement for hormone in promoting temperature-dependent transformation of cytosolic glucocorticoid receptors to the DNA-binding state.
The Journal of biological chemistry 1990;265(9):4863-70.
1990: F C Dalman; Ronald J Koenig; G H Perdew; E Massa; William B Pratt
In contrast to the glucocorticoid receptor, the thyroid hormone receptor is translated in the DNA binding state and is not associated with hsp90.
The Journal of biological chemistry 1990;265(7):3615-8.
1990: E H Bresnick; F C Dalman; William B Pratt
Direct stoichiometric evidence that the untransformed Mr 300,000, 9S, glucocorticoid receptor is a core unit derived from a larger heteromeric complex.
Biochemistry 1990;29(2):520-7.
1990: William B Pratt
Glucocorticoid receptor structure and the initial events in signal transduction.
Progress in clinical and biological research 1990;322():119-32.
1989: F C Dalman; E H Bresnick; Paresh D Patel; G H Perdew; Stanley J Watson Jr; William B Pratt
Direct evidence that the glucocorticoid receptor binds to hsp90 at or near the termination of receptor translation in vitro.
The Journal of biological chemistry 1989;264(33):19815-21.
1989: T Redmond; Edwin Ramon Sanchez; E H Bresnick; M J Schlesinger; D O Toft; William B Pratt; Michael J Welsh
Immunofluorescence colocalization of the 90-kDa heat-shock protein and microtubules in interphase and mitotic mammalian cells.
European journal of cell biology 1989;50(1):66-75.
1989: William B Pratt; Edwin Ramon Sanchez; E H Bresnick; S Meshinchi; L C Scherrer; F C Dalman; Michael J Welsh
Interaction of the glucocorticoid receptor with the Mr 90,000 heat shock protein: an evolving model of ligand-mediated receptor transformation and translocation.
Cancer research 1989;49(8 Suppl):2222s-2229s.
1989: E H Bresnick; F C Dalman; Edwin Ramon Sanchez; William B Pratt
Evidence that the 90-kDa heat shock protein is necessary for the steroid binding conformation of the L cell glucocorticoid receptor.
The Journal of biological chemistry 1989;264(9):4992-7.
1989: S Meshinchi; William B Pratt
Evidence that removal of an endogenous metal that stabilizes the untransformed glucocorticoid receptor in cytosol allows ligand-independent receptor transformation.
Journal of steroid biochemistry 1989;34(1-6):315-7.
1988: S Meshinchi; J F Grippo; Edwin Ramon Sanchez; E H Bresnick; William B Pratt
Evidence that the endogenous heat-stable glucocorticoid receptor stabilizing factor is a metal component of the untransformed receptor complex.
The Journal of biological chemistry 1988;263(32):16809-17.
1988: F C Dalman; Edwin Ramon Sanchez; A L Lin; F Perini; William B Pratt
Localization of phosphorylation sites with respect to the functional domains of the mouse L cell glucocorticoid receptor.
The Journal of biological chemistry 1988;263(25):12259-67.
1988: Edwin Ramon Sanchez; T Redmond; L C Scherrer; E H Bresnick; Michael J Welsh; William B Pratt
Evidence that the 90-kilodalton heat shock protein is associated with tubulin-containing complexes in L cell cytosol and in intact PtK cells.
Molecular endocrinology (Baltimore, Md.) 1988;2(8):756-60.
1988: E H Bresnick; Edwin Ramon Sanchez; R W Harrison; William B Pratt
Hydrogen peroxide stabilizes the steroid-binding state of rat liver glucocorticoid receptors by promoting disulfide bond formation.
Biochemistry 1988;27(8):2866-72.
1988: William B Pratt; D J Jolly; D V Pratt; S M Hollenberg; V Giguere; Françoise Cadepond; Ghislaine Schweizer-Groyer; Maria Grazia Catelli; R M Evans; Etienne Baulieu
A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.
The Journal of biological chemistry 1988;263(1):267-73.
1988: E H Bresnick; Edwin Ramon Sanchez; William B Pratt
Relationship between glucocorticoid receptor steroid-binding capacity and association of the Mr 90,000 heat shock protein with the unliganded receptor.
Journal of steroid biochemistry 1988;30(1-6):267-9.
1987: W Tienrungroj; Edwin Ramon Sanchez; Paul R Housley; R W Harrison; William B Pratt
Glucocorticoid receptor phosphorylation, transformation, and DNA binding.
The Journal of biological chemistry 1987;262(36):17342-9.
1987: Edwin Ramon Sanchez; S Meshinchi; M J Schlesinger; William B Pratt
Demonstration that the 90-kilodalton heat shock protein is bound to the glucocorticoid receptor in its 9S nondeoxynucleic acid binding form.
Molecular endocrinology (Baltimore, Md.) 1987;1(12):908-12.
1987: W Tienrungroj; S E Pratt; J F Grippo; A Holmgren; William B Pratt
The heat-stable cytosolic factor that promotes glucocorticoid receptor binding to DNA is neither thioredoxin nor ribonuclease.
Journal of steroid biochemistry 1987;28(5):449-57.
1987: William B Pratt
Transformation of glucocorticoid and progesterone receptors to the DNA-binding state.
Journal of cellular biochemistry 1987;35(1):51-68.
1987: W Tienrungroj; S Meshinchi; Edwin Ramon Sanchez; S E Pratt; J F Grippo; A Holmgren; William B Pratt
The role of sulfhydryl groups in permitting transformation and DNA binding of the glucocorticoid receptor.
The Journal of biological chemistry 1987;262(15):6992-7000.
1987: Edwin Ramon Sanchez; S Meshinchi; W Tienrungroj; M J Schlesinger; D O Toft; William B Pratt
Relationship of the 90-kDa murine heat shock protein to the untransformed and transformed states of the L cell glucocorticoid receptor.
The Journal of biological chemistry 1987;262(15):6986-91.
1986: Edwin Ramon Sanchez; William B Pratt
Phosphorylation of L-cell glucocorticoid receptors in immune complexes: evidence that the receptor is not a protein kinase.
Biochemistry 1986;25(6):1378-82.
1986: Edwin Ramon Sanchez; Paul R Housley; William B Pratt
The molybdate-stabilized glucocorticoid binding complex of L-cells contains a 98-100 kdalton steroid binding phosphoprotein and a 90 kdalton nonsteroid-binding phosphoprotein that is part of the murine heat-shock complex.
Journal of steroid biochemistry 1986;24(1):9-18.
1985: Paul R Housley; Edwin Ramon Sanchez; H M Westphal; M Beato; William B Pratt
The molybdate-stabilized L-cell glucocorticoid receptor isolated by affinity chromatography or with a monoclonal antibody is associated with a 90-92-kDa nonsteroid-binding phosphoprotein.
The Journal of biological chemistry 1985;260(25):13810-7.
1985: Edwin Ramon Sanchez; D O Toft; M J Schlesinger; William B Pratt
Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.
The Journal of biological chemistry 1985;260(23):12398-401.
1985: M K Dahmer; W Tienrungroj; William B Pratt
Purification and preliminary characterization of a macromolecular inhibitor of glucocorticoid receptor binding to DNA.
The Journal of biological chemistry 1985;260(12):7705-15.
1985: J F Grippo; A Holmgren; William B Pratt
Proof that the endogenous, heat-stable glucocorticoid receptor-activating factor is thioredoxin.
The Journal of biological chemistry 1985;260(1):93-7.
1984: S L Liu; J F Grippo; R P Erickson; William B Pratt
Murine glucocorticoid receptors and the H-2 locus--a reappraisal.
Journal of steroid biochemistry 1984;21(6):633-7.
1984: M K Dahmer; Paul R Housley; William B Pratt
Effects of molybdate and endogenous inhibitors on steroid-receptor inactivation, transformation, and translocation.
Annual review of physiology 1984;46():67-81.
1983: J F Grippo; W Tienrungroj; M K Dahmer; Paul R Housley; William B Pratt
Evidence that the endogenous heat-stable glucocorticoid receptor-activating factor is thioredoxin.
The Journal of biological chemistry 1983;258(22):13658-64.
1983: P R Housley; William B Pratt
Direct demonstration of glucocorticoid receptor phosphorylation by intact L-cells.
The Journal of biological chemistry 1983;258(7):4630-5.
1983: K L Leach; M K Dahmer; William B Pratt
Glucocorticoid receptor stabilization: relative effects of molybdate ion on inactivation by alkaline phosphatase and phospholipase A2.
Journal of steroid biochemistry 1983;18(1):105-7.
1982: Paul R Housley; M K Dahmer; William B Pratt
Inactivation of glucocorticoid-binding capacity by protein phosphatases in the presence of molybdate and complete reactivation of dithiothreitol.
The Journal of biological chemistry 1982;257(15):8615-8.
1982: K L Leach; R P Erickson; William B Pratt
The endogenous heat-stable glucocorticoid receptor stabilizing factor and the H-2 locus.
Journal of steroid biochemistry 1982;17(1):121-3.
1982: K L Leach; J F Grippo; Paul R Housley; M K Dahmer; M E Salive; William B Pratt
Characteristics of an endogenous glucocorticoid receptor stabilizing factor.
The Journal of biological chemistry 1982;257(1):381-8.
1981: M K Dahmer; M W Quasney; S T Bissen; William B Pratt
Molybdate permits resolution of untransformed glucocorticoid receptors from the transformed state.
The Journal of biological chemistry 1981;256(18):9401-5.
1981: R H Wheeler; K L Leach; A C La Forest; T E O'Toole; R Wagner; William B Pratt
Glucocorticoid receptor activation and inactivation in cultured human lymphocytes.
The Journal of biological chemistry 1981;256(1):434-41.
1980: William B Pratt; W G Phippen
Elevated hair copper level in idiopathic scoliosis: preliminary observations.
Spine 1980;5(3):230-3.
1979: K L Leach; M K Dahmer; N D Hammond; J J Sando; William B Pratt
Molybdate inhibition of glucocorticoid receptor inactivation and transformation.
The Journal of biological chemistry 1979;254(23):11884-90.
1979: J J Sando; N D Hammond; C A Stratford; William B Pratt
Activation of thymocyte glucocorticoid receptors to the steroid binding form. The roles of reduction agents, ATP, and heat-stable factors.
The Journal of biological chemistry 1979;254(11):4779-89.
1979: J J Sando; A C La Forest; William B Pratt
ATP-dependent activation of L cell glucocorticoid receptors to the steroid binding form.
The Journal of biological chemistry 1979;254(11):4772-8.
1979: William B Pratt; J J Sando; C J Nielsen
Glucocorticoid receptor inactivation and activation by phosphorylation mechanisms.
Advances in experimental medicine and biology 1979;117():343-56.
1978: M S Butley; R P Erickson; William B Pratt
Hepatic glucocorticoid receptors and the H-2 locus.
Nature 1978;275(5676):136-8.
1978: William B Pratt
The mechanism of glucocorticoid effects in fibroblasts.
The Journal of investigative dermatology 1978;71(1):24-35.
1977: J J Sando; C J Nielsen; William B Pratt
Reactivation of thymocyte glucocorticoid receptors in a cell-free system.
The Journal of biological chemistry 1977;252(21):7579-82.
1977: C J Nielsen; J J Sando; W Mark Vogel; William B Pratt
Glucocorticoid receptor inactivation under cell-free conditions.
The Journal of biological chemistry 1977;252(21):7568-78.
1977: A H El Masry; V C Braun; C J Nielsen; William B Pratt
Synthesis and biological action of two glucocorticoid alkylating agents.
Journal of medicinal chemistry 1977;20(9):1134-9.
1977: C J Nielsen; W Mark Vogel; William B Pratt
Inactivation of glucocorticoid receptors in cell-free preparations of rat liver.
Cancer research 1977;37(9):3420-6.
1977: C J Nielsen; J J Sando; William B Pratt
Evidence that dephosphorylation inactivates glucocorticoid receptors.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(4):1398-402.
1976: H F Schulte; C J Nielsen; J J Sando; William B Pratt
Evidence for a phospholipid requirement in the specific binding of glucocorticoids to receptors of fibroblasts and thymic lymphocytes.
The Journal of biological chemistry 1976;251(8):2279-89.
1975: J L Kaine; C J Nielsen; William B Pratt
The kinetics of specific glucocorticoid binding in rat thymus cytosol: evidence for the existence of multiple binding states.
Molecular pharmacology 1975;11(5):578-87.
1975: William B Pratt; J L Kaine; D V Pratt
The kinetics of glucocorticoid binding to the soluble specific binding protein of mouse fibroblasts.
The Journal of biological chemistry 1975;250(12):4584-91.
1972: D N Ishii; William B Pratt; L Aronow
Steady-state level of the specific glucocorticoid binding component in mouse fibroblasts.
Biochemistry 1972;11(21):3896-904.
1972: William B Pratt; D N Ishii
Specific binding of glucocorticoids in vitro in the soluble fraction of mouse fibroblasts.
Biochemistry 1972;11(8):1401-10.
1971: J F Hackney; William B Pratt
Characterization and partial purification of the specific glucocorticoid-binding component from mouse fibroblasts.
Biochemistry 1971;10(16):3002-8.
1971: J G Gray; William B Pratt; L Aronow
Effect of glucocorticoids on hexose uptake by mouse fibroblasts in vitro.
Biochemistry 1971;10(2):277-84.
1970: J F Hackney; S R Gross; L Aronow; William B Pratt
Specific glucocorticoid-binding macromolecules from mouse fibroblasts growing in vitro. A possible steroid receptor for growth inhibition.
Molecular pharmacology 1970;6(5):500-12.
1970: J Gomez; Wilfred Byron Kemper; William B Pratt; L Aronow
Effects of glucocorticoids on nucleic acid synthesis in mouse lymphoma cells growing in vitro and on nuclei isolated from these cells.
Biochemical pharmacology 1970;19(4):1471-83.
1970: S R Gross; L Aronow; William B Pratt
The outward transport of cortisol by mammalian cells in vitro.
The Journal of cell biology 1970;44(1):103-14.
1969: Wilfred Byron Kemper; William B Pratt; L Aronow
Nucleic acid synthesis in intact nuclei isolated from mouse fibroblasts. Characterization of the system and effects of glucocorticoids.
Molecular pharmacology 1969;5(5):507-31.
1969: Wilfred Byron Kemper; William B Pratt; L Aronow
Effects of glucocorticoids on nucleic acid synthesis in intact nuclei isolated from mouse fibroblasts.
Proceedings of the Western Pharmacology Society 1969;12():69-71.
1969: S R Gross; L Arow; William B Pratt
The active transport of cortisol by mouse fibroblasts growing in vitro.
Proceedings of the Western Pharmacology Society 1969;12():54-8.
1968: S R Gross; L Aronow; William B Pratt
The active transport of cortisol by mouse fibroblasts growing in vitro.
Biochemical and biophysical research communications 1968;32(1):66-72.
1968: William B Pratt; S R Gross; L Aronow
Endosymbionts as a source of cytoplasmic satellite deoxyribonucleic acid.
Journal of molecular biology 1968;33(2):521-5.
1967: William B Pratt; S Edelman; L Aronow
The effect of cortisol, administered in vivo, on the in vitro incorporation of DNA and RNA precursors by rat thymus cells.
Molecular pharmacology 1967;3(3):219-24.
1966: William B Pratt; L Aronow
The effect of glucocorticoids on protein and nucleic acid synthesis in mouse fibroblasts growing in vitro.
The Journal of biological chemistry 1966;241(22):5244-50.
1965: A Wacker; J Drews; William B Pratt; H Laurent; K Petzoldt
[Enzyme induction with steroids in Pseudomonas testosteroni].
Zeitschrift für Naturforschung. Teil B: Chemie, Biochemie, Biophysik, Biologie 1965;20(6):547-53.