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Maria Preobrazhenskaya

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Lyudmila N Lysenkova; Alexander A Shtil; Konstantin F Turchin; Olga B Bekker; VN Danilenko; Lyubov G Dezhenkova; Alexander M Korolev; Maria N Preobrazhenskaya
Synthesis and cytotoxicity of oligomycin A derivatives modified in the side chain.
Ss Printsevskaya; Mi Reznikova; Am Korolev; Gb Lapa; En Olsufyeva; Jj Plattner; Maria N Preobrazhenskaya; Yk Zhang
Synthesis and study of antibacterial activities of antibacterial glycopeptide antibiotics conjugated with benzoxaboroles.
Ida Aronchik; Leonard F Bjeldanes; Tony Chen; Kathleen A Durkin; Marshall S Horwitz; Maria N Preobrazhenskaya; Gary L Firestone
Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.

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2013: Lyudmila N Lysenkova; Alexander A Shtil; Konstantin F Turchin; Olga B Bekker; VN Danilenko; Lyubov G Dezhenkova; Alexander M Korolev; Maria N Preobrazhenskaya
Synthesis and cytotoxicity of oligomycin A derivatives modified in the side chain.
Bioorganic & medicinal chemistry 2013;21(11):2918-24.
2013: Ss Printsevskaya; Mi Reznikova; Am Korolev; Gb Lapa; En Olsufyeva; Jj Plattner; Maria N Preobrazhenskaya; Yk Zhang
Synthesis and study of antibacterial activities of antibacterial glycopeptide antibiotics conjugated with benzoxaboroles.
Future medicinal chemistry 2013;5(6):641-52.
2012: Ida Aronchik; Leonard F Bjeldanes; Tony Chen; Kathleen A Durkin; Marshall S Horwitz; Maria N Preobrazhenskaya; Gary L Firestone
Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
Molecular carcinogenesis 2012;51(11):881-94.
2012: Lyudmila N Lysenkova; Alexander A Shtil; AS Trenin; Konstantin F Turchin; Olga B Bekker; Evgenyi E Bykov; VN Danilenko; Lyubov G Dezhenkova; SM Elizarov; Alexander M Korolev; Maria N Preobrazhenskaya
A novel acyclic oligomycin A derivative formed via retro-aldol rearrangement of oligomycin A.
The Journal of antibiotics 2012;65(8):405-11.
2012: Lyudmila N Lysenkova; Olga B Bekker; Valery N Danilenko; Alexander M Korolev; Alexander A Shtil; AS Trenin; Konstantin F Turchin; Maria N Preobrazhenskaya
Synthesis and properties of a novel brominated oligomycin A derivative.
The Journal of antibiotics 2012;65(4):223-5.
2012: Tine De Burghgraeve; Xavier de Lamballerie; Andrea V Gamarnik; Michael Jacobs; Suzanne J F Kaptein; Juan A Mondotte; Boris Pastorino; Maria N Preobrazhenskaya; Svetlana S Printsevskaya; Jolanda M Smit; Nilda V Ayala-Nunez; Johan Neyts
An analogue of the antibiotic teicoplanin prevents flavivirus entry in vitro.
PloS one 2012;7(5):e37244.
2011: Anna N Tevyashova; Alexander M Vinogradov; Marina I Reznikova; Alexander A Shtil; VM Bukhman; Lyubov G Dezhenkova; Nikita A Durandin; Elena B Isakova; Vladimir A Kuzmin; Yuri N Luzikov; Evgenia N Olsufyeva; Maria N Preobrazhenskaya
Modification of olivomycin A at the side chain of the aglycon yields the derivative with perspective antitumor characteristics.
Bioorganic & medicinal chemistry 2011;19(24):7387-93.
2011: Susan Obeid; Svetlana S Printsevskaya; Evgenia N Olsufyeva; Kai Dallmeier; David Durantel; Fabien Zoulim; Maria N Preobrazhenskaya; Johan Neyts; Jan Paeshuyse
Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics.
The Journal of antimicrobial chemotherapy 2011;66(6):1287-94.
2011: Valery N Danilenko; Dmitry I Osolodkin; Sergey A Lakatosh; Maria N Preobrazhenskaya; Alexander A Shtil
Bacterial eukaryotic type serine-threonine protein kinases: from structural biology to targeted anti-infective drug design.
Current topics in medicinal chemistry 2011;11(11):1352-69.
2011: Andrey E Shchekotikhin; Valeria A Glazunova; Lyubov G Dezhenkova; Elena K Shevtsova; Valery F Traven'; Jan Balzarini; Hsu-Shan Huang; Alexander A Shtil; Maria N Preobrazhenskaya
The first series of 4,11-bis[(2-aminoethyl)amino]anthra[2,3-b]furan-5,10-diones: Synthesis and anti-proliferative characteristics.
European journal of medicinal chemistry 2011;46(1):423-8.
2010: I B Cheglakov; Anna N Tevyashova; L K Kurbatov; V V Tatarsky; Alexei V Samusenko; Maria N Preobrazhenskaya; Alexander A Shtil
Altered transcription and replication are the mechanisms of cytotoxicity of antitumor antibiotic olivomycin A.
Doklady. Biochemistry and biophysics 2010;435():320-2.
2010: Sergey N Lavrenov; Yuri N Luzikov; Evgeniy E Bykov; Marina I Reznikova; Evgenia V Stepanova; Valeria A Glazunova; Yulia L Volodina; Victor V Tatarsky; Alexander A Shtil; Maria N Preobrazhenskaya
Synthesis and cytotoxic potency of novel tris(1-alkylindol-3-yl)methylium salts: role of N-alkyl substituents.
Bioorganic & medicinal chemistry 2010;18(18):6905-13.
2010: Hanh H Nguyen; Sergey N Lavrenov; Shyam N Sundar; David H H Nguyen; Min Tseng; Crystal N Marconett; Jenny Kung; Richard E Staub; Maria N Preobrazhenskaya; Leonard F Bjeldanes; Gary L Firestone
1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells.
Chemico-biological interactions 2010;186(3):255-66.
2010: Maria N Preobrazhenskaya; Evgenia N Olsufyeva; Anna N Tevyashova; Svetlana S Printsevskaya; Svetlana E Solovieva; Marina I Reznikova; AS Trenin; Olga A Galatenko; Ivan D Treshalin; ER Pereverzeva; Elena P Mirchink; Sergey B Zotchev
Synthesis and study of the antifungal activity of new mono- and disubstituted derivatives of a genetically engineered polyene antibiotic 28,29-didehydronystatin A1 (S44HP).
The Journal of antibiotics 2010;63(2):55-64.
2010: Lyudmila N Lysenkova; Konstantin F Turchin; Valery N Danilenko; Alexander M Korolev; Maria N Preobrazhenskaya
The first examples of chemical modification of oligomycin A.
The Journal of antibiotics 2010;63(1):17-22.
2009: Anna N Tevyashova; Eugenia N Olsufyeva; Konstantin F Turchin; Jan Balzarini; Eugenyi E Bykov; Lyubov G Dezhenkova; Alexander A Shtil; Maria N Preobrazhenskaya
Reaction of the antitumor antibiotic olivomycin I with aryl diazonium salts. Synthesis, cytotoxic and antiretroviral potency of 5-aryldiazenyl-6-O-deglycosyl derivatives of olivomycin I.
Bioorganic & medicinal chemistry 2009;17(14):4961-7.
2009: Andrey E Shchekotikhin; Valeria A Glazunova; Lyubov G Dezhenkova; Yuri N Luzikov; Yuri B Sinkevich; Leonid V Kovalenko; Vladimir N Buyanov; Jan Balzarini; Fong-Chun Huang; Jing-Jer Lin; Hsu-Shan Huang; Alexander A Shtil; Maria N Preobrazhenskaya
Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones.
Bioorganic & medicinal chemistry 2009;17(5):1861-9.
2009: Maria N Preobrazhenskaya; Evgenia N Olsufyeva; Svetlana E Solovieva; Anna N Tevyashova; Marina I Reznikova; Yuryi N Luzikov; Larisa P Terekhova; Aleksei S Trenin; Olga A Galatenko; Ivan D Treshalin; Elena P Mirchink; Vladimir M Bukhman; Håvard Sletta; Sergey B Zotchev
Chemical modification and biological evaluation of new semisynthetic derivatives of 28,29-Didehydronystatin A1 (S44HP), a genetically engineered antifungal polyene macrolide antibiotic.
Journal of medicinal chemistry 2009;52(1):189-96.
2009: Anna N Tevyashova; Eugenia N Olsufyeva; Eugenia N Zbarsky; Jan Balzarini; Alexander A Shtil; Lyubov G Dezhenkova; Vladimir M Bukhman; Victor B Zbarsky; Maria N Preobrazhenskaya
Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.
The Journal of antibiotics 2009;62(1):37-41.
2008: Valery N Danilenko; Alexander Y Simonov; Sergey A Lakatosh; Michael H G Kubbutat; Frank Totzke; Christoph Schächtele; Sergey M Elizarov; Olga B Bekker; Svetlana S Printsevskaya; Yuryi N Luzikov; Marina I Reznikova; Alexander A Shtil; Maria N Preobrazhenskaya
Search for inhibitors of bacterial and human protein kinases among derivatives of diazepines[1,4] annelated with maleimide and indole cycles.
Journal of medicinal chemistry 2008;51(24):7731-6.
2008: L G Dezhenkova; O Y Susova; Andrey E Shchekotikhin; Maria N Preobrazhenskaya; Alexander A Shtil
Naphtho[2,3-f]indole-5,10-dione aminoalkyl derivatives: a new class of topoisomerase I inhibitors.
Bulletin of experimental biology and medicine 2008;145(3):334-7.
2008: Sarah M Jump; Jenny Kung; Richard E Staub; Matthew A Kinseth; EJ Cram; Larisa N Yudina; Maria N Preobrazhenskaya; Leonard F Bjeldanes; Gary L Firestone
N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells.
Biochemical pharmacology 2008;75(3):713-24.
2007: Kirk R Maples; Conrad Wheeler; Emily Ip; Jacob J Plattner; Daniel Chu; Yong-Kang Zhang; Maria N Preobrazhenskaya; Svetlana S Printsevskaya; Svetlana E Solovieva; Evgenia N Olsufyeva; Henry Heine; Julie Lovchik; C Rick Lyons
Novel semisynthetic derivative of antibiotic Eremomycin active against drug-resistant gram-positive pathogens including Bacillus anthracis.
Journal of medicinal chemistry 2007;50(15):3681-5.
2007: Jacob J Plattner; Daniel Chu; Elena P Mirchink; Elena B Isakova; Maria N Preobrazhenskaya; Evgenia N Olsufyeva; Olga V Miroshnikova; Svetlana S Printsevskaya
N'-(alpha-aminoacyl)- and N'-alpha-(N-alkylamino)acyl derivatives of vancomycin and eremomycin. II. Antibacterial activity of N'-(alpha-aminoacyl)- and N'-alpha-(N-alkylamino)acyl derivatives of vancomycin and eremomycin.
The Journal of antibiotics 2007;60(4):245-50.
2007: Maria N Preobrazhenskaya; Evgenia N Olsufyeva; Olga V Miroshnikova; Jacob J Plattner; Daniel Chu; Svetlana S Printsevskaya
N'-(alpha-aminoacyl)- and N'-alpha-(N(alpha)-alkylamino)acyl derivatives of vancomycin and eremomycin. I. Synthesis of N'-(alpha-aminoacyl)- and N'-alpha-(N(alpha)-alkylamino)acyl derivatives of vancomycin and eremomycin by selective aminoacylation of the amino sugar of the disaccharide branch.
The Journal of antibiotics 2007;60(4):235-44.
2007: Andrey E Shchekotikhin; Lyubov G Dezhenkova; Olga Yu Susova; Valeria A Glazunova; Yuri N Luzikov; Yuri B Sinkevich; Vladimir N Buyanov; Alexander A Shtil; Maria N Preobrazhenskaya
Naphthoindole-based analogues of tryptophan and tryptamine: synthesis and cytotoxic properties.
Bioorganic & medicinal chemistry 2007;15(7):2651-9.
2006: Jan Balzarini; Els Keyaerts; Leen Vijgen; Herman Egberink; Erik De Clercq; Marc Van Ranst; Svetlana S Printsevskaya; Evgenia N Olsufyeva; Svetlana E Solovieva; Maria N Preobrazhenskaya
Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics.
Antiviral research 2006;72(1):20-33.
2006: Maria N Preobrazhenskaya; Evgenia N Olsufyeva
Polycyclic peptide and glycopeptide antibiotics and their derivatives as inhibitors of HIV entry.
Antiviral research 2006;71(2-3):227-36.
2006: Andrey E Shchekotikhin; Valeria A Glazunova; Yuri N Luzikov; Vladimir N Buyanov; Olga Yu Susova; Alexander A Shtil; Maria N Preobrazhenskaya
Synthesis and structure-activity relationship studies of 4,11-diaminonaphtho[2,3-f]indole-5,10-diones.
Bioorganic & medicinal chemistry 2006;14(15):5241-51.
2006: Sung Joon Kim; Lynette Cegelski; Maria N Preobrazhenskaya; Jacob Schaefer
Structures of Staphylococcus aureus cell-wall complexes with vancomycin, eremomycin, and chloroeremomycin derivatives by 13C{19F} and 15N{19F} rotational-echo double resonance.
Biochemistry 2006;45(16):5235-50.
2005: Sonia I Maffioli; Romeo Ciabatti; Gabriella Romanò; Ettore Marzorati; Maria N Preobrazhenskaya; Andrej Pavlov
Synthesis and antibacterial activity of alkyl derivatives of the glycopeptide antibiotic A40926 and their amides.
Bioorganic & medicinal chemistry letters 2005;15(16):3801-5.
2005: Svetlana S Printsevskaya; Svetlana E Solovieva; Evgenia N Olsufyeva; Elena P Mirchink; Elena B Isakova; Erik De Clercq; Jan Balzarini; Maria N Preobrazhenskaya
Structure-activity relationship studies of a series of antiviral and antibacterial aglycon derivatives of the glycopeptide antibiotics vancomycin, eremomycin, and dechloroeremomycin.
Journal of medicinal chemistry 2005;48(11):3885-90.
2005: Andrey E Shchekotikhin; Alexander A Shtil; Yuri N Luzikov; Tatyana V Bobrysheva; Vladimir N Buyanov; Maria N Preobrazhenskaya
3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance.
Bioorganic & medicinal chemistry 2005;13(6):2285-91.
2004: Andrey E Shchekotikhin; Vladimir N Buyanov; Maria N Preobrazhenskaya
Synthesis of 1-(omega-aminoalkyl)naphthoindolediones with antiproliferative properties.
Bioorganic & medicinal chemistry 2004;12(14):3923-30.
2004: Anna N Tevyashova; Alexander A Shtil; Evgenia N Olsufyeva; Valeria S Simonova; Alexei V Samusenko; Maria N Preobrazhenskaya
Carminomycin, 14-hydroxycarminomycin and its novel carbohydrate derivatives potently kill human tumor cells and their multidrug resistant variants.
The Journal of antibiotics 2004;57(2):143-50.
2004: Irina S Severina; Natalya V Pyatakova; Alexander Postnikov; Maria N Preobrazhenskaya; Yuri V Khropov
Antitumor antibiotic streptonigrin and its derivatives as inhibitors of nitric oxide-dependent activation of soluble guanylyl cyclase.
European journal of pharmacology 2004;483(2-3):127-32.
2004: Sergey Lavrenov; N P Solovyeva; Marina I Reznikova; O S Anisimova; Maria N Preobrazhenskaya
The interaction of per-O-acetylated acyclic 1-(1-butylindol-3-yl)-1-deoxy-ketoses with silylated uracil.
Nucleosides, nucleotides & nucleic acids 2004;23(1-2):281-9.
2003: Evgenia N Olsufyeva; Anna N Tevyashova; Ivan D Trestchalin; Maria N Preobrazhenskaya; David Platt; Anatole Klyosov
Synthesis and antitumor activity of new D-galactose-containing derivatives of doxorubicin.
Carbohydrate research 2003;338(13):1359-67.
2003: Jan Balzarini; Christophe Pannecouque; Erik De Clercq; Andrey Y Pavlov; Svetlana S Printsevskaya; Olga V Miroshnikova; Marina I Reznikova; Maria N Preobrazhenskaya
Antiretroviral activity of semisynthetic derivatives of glycopeptide antibiotics.
Journal of medicinal chemistry 2003;46(13):2755-64.
2003: Robert Pearlstein; Roy J Vaz; Jiesheng Kang; Xiao-Liang Chen; Maria N Preobrazhenskaya; Andrey E Shchekotikhin; Alexander M Korolev; Ludmila N Lysenkova; Olga V Miroshnikova; James Hendrix; David Rampe
Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.
Bioorganic & medicinal chemistry letters 2003;13(10):1829-35.
2003: Svetlana S Printsevskaya; Andrey Y Pavlov; Evgenia N Olsufyeva; Elena P Mirchink; Maria N Preobrazhenskaya
Role of the glycopeptide framework in the antibacterial activity of hydrophobic derivatives of glycopeptide antibiotics.
Journal of medicinal chemistry 2003;46(7):1204-9.
2003: Sergey A Lakatosh; Yuri N Luzikov; Maria N Preobrazhenskaya
Synthesis of 6H-pyrrolo[3',4':2,3][1,4]diazepino[6,7,1-hi]indole-8,10(7H,9H)-diones using 3-bromo-4-(indol-1-yl)maleimide scaffold.
Organic & biomolecular chemistry 2003;1(5):826-33.
2003: Sergey Lavrenov; Alexander M Korolev; Marina I Reznikova; Andrey Sosnov; Maria N Preobrazhenskaya
Study of 1-deoxy-1-(indol-3-yl)-L-sorbose, 1-deoxy-1-(indol-3-yl)-L-tagatose, and their analogs.
Carbohydrate research 2003;338(2):143-52.
2002: S A Lakatosh; J Balzarini; G Andrei; R Snoeck; A Lakatosh; E De Clercq; Maria N Preobrazhenskaya
Synthesis, and cytotoxic activity of N(ind)-alkoxy derivatives of antibiotic arcyriarubin and dechloro-rebeccamycin aglycon.
The Journal of antibiotics 2002;55(8):768-73.
2002: Svetlana S Printsevskaya; Andrey Y Pavlov; Evgenia N Olsufyeva; Elena P Mirchink; Elena B Isakova; Marina I Reznikova; Robert C Goldman; Arthur A Branstrom; Eugene R Baizman; Clifford B Longley; Ferenc Sztaricskai; Gyula Batta; Maria N Preobrazhenskaya
Synthesis and mode of action of hydrophobic derivatives of the glycopeptide antibiotic eremomycin and des-(N-methyl-D-leucyl)eremomycin against glycopeptide-sensitive and -resistant bacteria.
Journal of medicinal chemistry 2002;45(6):1340-7.
2002: Olga V Leontieva; Maria N Preobrazhenskaya; Ralph J Bernacki
Partial circumvention of P-glycoprotein-mediated multidrug resistance by doxorubicin-14-O-hemiadipate.
Investigational new drugs 2002;20(1):35-48.
2001: Sergey Lavrenov; A M Korolev; Maria N Preobrazhenskaya
O-glycosides of N-hydroxyindoles.
Nucleosides, nucleotides & nucleic acids 2001;20(10-11):1881-9.
2001: Andrey Y Pavlov; Olga V Miroshnikova; Svetlana S Printsevskaya; Evgenia N Olsufyeva; Maria N Preobrazhenskaya; Robert C Goldman; Arthur A Branstrom; Eugene R Baizman; Clifford B Longley
Synthesis of hydrophobic N'-mono and N',N"-double alkylated eremomycins inhibiting the transglycosylation stage of bacterial cell wall biosynthesis.
The Journal of antibiotics 2001;54(5):455-9.
2001: Ferenc Sztaricskai; Gyula Batta; Zoltán Dinya; Olga V Miroshnikova; Maria N Preobrazhenskaya; Ferenc Hernádi; András Koncz; Zoltán Boda
Chemical modification of the eremomycin antibiotic. Formation of a cyclic covalent dimer.
The Journal of antibiotics 2001;54(3):314-9.
2001: Alexander M Korolev; L N Yudina; I I Rozhkov; L N Lysenkova; EI Lazhko; Yuri N Luzikov; Maria N Preobrazhenskaya
The formation of 2-hydroxy-4-hydroxymethyl-3-(indol-3-yl)-cyclopent-2-enone derivatives from ascorbigens.
Carbohydrate research 2001;330(4):469-77.
2000: Olga V Miroshnikova; Svetlana S Printsevskaya; Evgenia N Olsufyeva; Andrey Y Pavlov; Angela M Nilius; D Hensey-Rudloff; Maria N Preobrazhenskaya
Structure-activity relationships in the series of eremomycin carboxamides.
The Journal of antibiotics 2000;53(3):286-93.
1999: Evgenia N Olsufyeva; T F Berdnikova; Olga V Miroshnikova; Marina I Reznikova; Maria N Preobrazhenskaya
Chemical modification of antibiotic eremomycin at the asparagine side chain.
The Journal of antibiotics 1999;52(3):319-24.
1998: Andrey Y Pavlov; Maria N Preobrazhenskaya; A Malabarba; Romeo Ciabatti
Synthesis and antibacterial activity of derivatives of the glycopeptide antibiotic A-40926 N-alkylated at the aminoglucuronyl moiety.
The Journal of antibiotics 1998;51(5):525-7.
1998: Andrey Y Pavlov; Maria N Preobrazhenskaya; A Malabarba; Romeo Ciabatti; L Colombo
Mono and double modified teicoplanin aglycon derivatives on the amino acid no. 7; structure-activity relationship.
The Journal of antibiotics 1998;51(1):73-8.
1997: Andrey Y Pavlov; EI Lazhko; Maria N Preobrazhenskaya
A new type of chemical modification of glycopeptides antibiotics: aminomethylated derivatives of eremomycin and their antibacterial activity.
The Journal of antibiotics 1997;50(6):509-13.
1997: A Malabarba; Romeo Ciabatti; E Gerli; F Ripamonti; P Ferrari; L Colombo; Evgenia N Olsufyeva; Andrey Y Pavlov; Marina I Reznikova; EI Lazhko; Maria N Preobrazhenskaya
Substitution of amino acids 1 and 3 in teicoplanin aglycon: synthesis and antibacterial activity of three first non-natural dalbaheptides.
The Journal of antibiotics 1997;50(1):70-81.
1996: Olga V Miroshnikova; T F Berdnikova; Evgenia N Olsufyeva; Andrey Y Pavlov; Marina I Reznikova; Maria N Preobrazhenskaya; Romeo Ciabatti; A Malabarba; L Colombo
A modification of the N-terminal amino acid in the eremomycin aglycone.
The Journal of antibiotics 1996;49(11):1157-61.
1996: Andrey Y Pavlov; T F Berdnikova; Evgenia N Olsufyeva; Olga V Miroshnikova; S T Filipposyanz; Maria N Preobrazhenskaya; C Sottani; L Columbo; B P Goldstein
Carboxamides and hydrazide of glycopeptide antibiotic eremomycin. Synthesis and antibacterial activity.
The Journal of antibiotics 1996;49(2):194-8.
1995: Maria N Preobrazhenskaya; A M Korolev; N N Isaeva; EI Lazhko; L A Lomidze
Polyfunctional indole-3-carbinol derivatives: 1-(indol-3-yl)glycerols and related compounds, beta-hydroxytryptamines and ascorbigens. Chemistry and biological properties.
Farmaco (Società chimica italiana : 1989) 1995;50(6):369-77.
1994: S V Komissarenko; O P Penezina; G N Fomovskaya; V V Tolstikov; Maria N Preobrazhenskaya
Selective killing of tumor cells in vitro by immunotoxin composed of antitumor antibiotic streptonigrin and polyclonal specific antibodies.
International journal of immunopharmacology 1994;16(12):1053-8.
1994: Andrey Y Pavlov; Evgenia N Olsufyeva; T F Berdnikova; I V Malkova; Maria N Preobrazhenskaya; G D Risbridger
Modification of glycopeptide antibiotic eremomycin by the action of alkyl halides and study on antibacterial activity of the compounds obtained.
The Journal of antibiotics 1994;47(2):225-32.
1994: S R Musk; Maria N Preobrazhenskaya; G A Belitsky; A M Korolev; T A Lytcheva; I A Khitrovo; Ian Johnson
The clastogenic and mutagenic effects of ascorbigen and 1'-methylascorbigen.
Mutation research 1994;323(1-2):69-74.
1993: Andrey Y Pavlov; T F Berdnikova; Evgenia N Olsufyeva; EI Lazhko; I V Malkova; Maria N Preobrazhenskaya; Raymond T Testa; Peter J Petersen
Synthesis and biological activity of derivatives of glycopeptide antibiotics eremomycin and vancomycin nitrosated, acylated or carbamoylated at the N-terminal.
The Journal of antibiotics 1993;46(11):1731-9.
1993: Maria N Preobrazhenskaya; V M Bukhman; A M Korolev; S A Efimov
Ascorbigen and other indole-derived compounds from Brassica vegetables and their analogs as anticarcinogenic and immunomodulating agents.
Pharmacology & therapeutics 1993;60(2):301-13.
1992: Maria N Preobrazhenskaya; A M Korolev
Indole-3-carbinol.
Journal of the National Cancer Institute 1992;84(15):1210-2.
1992: V V Tolstikov; N V Kozlova; T D Oreshkina; T V Osipova; Maria N Preobrazhenskaya; F Sztaricskai; J Balzarini; E De Clercq
Amides of antibiotic streptonigrin and amino dicarboxylic acids or aminosugars. Synthesis and biological evaluation.
The Journal of antibiotics 1992;45(6):1020-5.
1992: V V Tolstikov; Maria N Preobrazhenskaya; J Balzarini; E De Clercq
Chemical modification of antibiotic streptonigrin; synthesis and properties of 2'-decarboxy-2'-aminostreptonigrin (streptonigrone-2'-imine).
The Journal of antibiotics 1992;45(6):1002-4.
1992: Maria N Preobrazhenskaya; N V Holpne-Kozlova; EI Lazhko
Transformation of streptonigrin into streptonigrone; synthesis and biological evaluation of antibiotics streptonigrin and streptonigrone alkyl ethers.
The Journal of antibiotics 1992;45(2):227-34.
1991: I V Malkova; V M Bukhman; I V Vinogradova; T V Fomina; A M Korolev; Maria N Preobrazhenskaya
Prophylaxis of experimental bacterial infection in mice by 1'-methylascorbigen.
The Journal of antimicrobial chemotherapy 1991;28(6):935-6.
1991: Maria N Preobrazhenskaya; E V Bakina; L S Povarov; EI Lazhko; L G Aleksandrova; J Balzarini; E De Clercq
Synthesis and cytostatic properties of daunorubicin derivatives, containing N-phenylthiourea or N-ethylthiourea moieties in the 3'-position.
The Journal of antibiotics 1991;44(2):192-9.