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Remko Prevo

Research Profile

Chemicals & Drugs

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Mouse

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Publications

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Nils H Nicolay; Remko Prevo; Niklas Schultz; Rebecca Carter; Stephanie B Hatch; Thomas Helleday; W Gillies McKenna; Ricky A Sharma
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
Remko Prevo; Philip M Reaper; Peter A Charlton; Emmanouil Fokas; W Gillies McKenna; Ruth J Muschel; John R Pollard; Thomas B Brunner
The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.
E Fokas; W Gillies McKenna; Ester M Hammond; Ruth J Muschel; M M Olcina; J R Pollard; Remko Prevo; P M Reaper; Katherine A Vallis; P A Charlton; B Cornelissen; T B Brunner
Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

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2012: Nils H Nicolay; Remko Prevo; Niklas Schultz; Rebecca Carter; Stephanie B Hatch; Thomas Helleday; W Gillies McKenna; Ricky A Sharma
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
Carcinogenesis 2012;33(11):2026-34.
2012: Remko Prevo; Philip M Reaper; Peter A Charlton; Emmanouil Fokas; W Gillies McKenna; Ruth J Muschel; John R Pollard; Thomas B Brunner
The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.
Cancer biology & therapy 2012;13(11):1072-81.
2012: E Fokas; W Gillies McKenna; Ester M Hammond; Ruth J Muschel; M M Olcina; J R Pollard; Remko Prevo; P M Reaper; Katherine A Vallis; P A Charlton; B Cornelissen; T B Brunner
Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.
Cell death & disease 2012;3():e441.
2012: Emmanouil Fokas; Wolfgang Hackl; Geoff Higgins; Sauveur-Michel Maira; W Gillies McKenna; Remko Prevo; Michio Yoshimura; Eric J Bernhard; Ruth J Muschel
NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity.
Radiation oncology (London, England) 2012;7():48.
2010: Geoff S Higgins; Adrian L Harris; Remko Prevo; Thomas Helleday; W Gillies McKenna; Francesca M Buffa
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
Oncotarget 2010;1(3):175-84.
2010: Geoff S Higgins; Remko Prevo; Yin-Fai Lee; Thomas Helleday; Ruth J Muschel; Steve Taylor; Michio Yoshimura; Ian D Hickson; Eric J Bernhard; W Gillies McKenna
A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.
Cancer research 2010;70(7):2984-93.
2008: Remko Prevo; Eric Deutsch; Oliver Sampson; Julie Diplexcito; Keith Cengel; Jane Harper; Peter O'Neill; W Gillies McKenna; Sonal Patel; Eric J Bernhard
Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity.
Cancer research 2008;68(14):5915-23.
2007: Louise A Johnson; Remko Prevo; Steven Clasper; David G Jackson
Inflammation-induced uptake and degradation of the lymphatic endothelial hyaluronan receptor LYVE-1.
The Journal of biological chemistry 2007;282(46):33671-80.
2007: Antonio Manzo; Serena Bugatti; Roberto Caporali; Remko Prevo; David G Jackson; Mariagrazia Uguccioni; Christopher D Buckley; Carlomaurizio Montecucco; Costantino Pitzalis
CCL21 expression pattern of human secondary lymphoid organ stroma is conserved in inflammatory lesions with lymphoid neogenesis.
The American journal of pathology 2007;171(5):1549-62.
2007: nicholas gale; Remko Prevo; Jorge Espinosa; David J P Ferguson; Melissa G Dominguez; George D Yancopoulos; Gavin Thurston; David G Jackson
Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1.
Molecular and cellular biology 2007;27(2):595-604.
2005: Takao Kato; Remko Prevo; Graham Steers; H Roberts; Russell Leek; Tsunehito Kimura; Shingo Kameoka; Toshio Nishikawa; M Kobayashi; David G Jackson; Adrian L Harris; Kevin C Gatter; Francesco Pezzella
A quantitative analysis of lymphatic vessels in human breast cancer, based on LYVE-1 immunoreactivity.
British journal of cancer 2005;93(10):1168-74.
2004: Remko Prevo; Suneale Banerji; Jian Ni; David G Jackson
Rapid plasma membrane-endosomal trafficking of the lymph node sinus and high endothelial venule scavenger receptor/homing receptor stabilin-1 (FEEL-1/CLEVER-1).
The Journal of biological chemistry 2004;279(50):52580-92.
2004: Anneke Engering; Sandra J van Vliet; Konnie Hebeda; David G Jackson; Remko Prevo; Satwinder K Singh; Teunis B H Geijtenbeek; Han van Krieken; Yvette van Kooyk
Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes.
The American journal of pathology 2004;164(5):1587-95.
2003: H Xu; J Edwards; Suneale Banerji; Remko Prevo; David G Jackson; N A Athanasou
Distribution of lymphatic vessels in normal and arthritic human synovial tissues.
Annals of the rheumatic diseases 2003;62(12):1227-9.
2003: Cory S M Williams; Russell Leek; Alistair M Robson; Suneale Banerji; Remko Prevo; Adrian L Harris; David G Jackson
Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer.
The Journal of pathology 2003;200(2):195-206.
2002: Nigel J P Beasley; Remko Prevo; Suneale Banerji; Russell Leek; John Moore; Philippe O van Trappen; Graham Cox; Adrian L Harris; David G Jackson
Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer.
Cancer research 2002;62(5):1315-20.
2001: David G Jackson; Remko Prevo; Steven Clasper; Suneale Banerji
LYVE-1, the lymphatic system and tumor lymphangiogenesis.
Trends in immunology 2001;22(6):317-21.
2001: Remko Prevo; Suneale Banerji; David J P Ferguson; Steven Clasper; David G Jackson
Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium.
The Journal of biological chemistry 2001;276(22):19420-30.
2001: Berndt Enholm; Terhi Karpanen; Michael Jeltsch; Hajime Kubo; F Stenback; Remko Prevo; David G Jackson; Seppo Yla-Herttuala; Kari Alitalo
Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin.
Circulation research 2001;88(6):623-9.
2001: Stefano J Mandriota; Lotta Jussila; Michael Jeltsch; A Compagni; Danielle Baetens; Remko Prevo; Suneale Banerji; J Huarte; Roberto Montesano; David G Jackson; Lelio Orci; Kari Alitalo; Gerhard Christofori; Michael S Pepper
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis.
The EMBO journal 2001;20(4):672-82.
2001: Mihaela Skobe; Thomas Hawighorst; David G Jackson; Remko Prevo; Lauren Janes; Paula Velasco; Lucia Riccardi; Kari Alitalo; Kevin P Claffey; Michael Detmar
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis.
Nature medicine 2001;7(2):192-8.
2001: Steven A Stacker; Carol Caesar; Megan E Baldwin; G E Thornton; Richard A Williams; Remko Prevo; David G Jackson; S Nishikawa; Hajime Kubo; Marc G Achen
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics.
Nature medicine 2001;7(2):186-91.