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Paul Price

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Bone and Bones

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Po-Yu Chen; Damon Toroian; Paul A Price; Joanna McKittrick
Minerals form a continuum phase in mature cancellous bone.
Paul A Price; Damon Toroian; Joo Eun Lim
Mineralization by inhibitor exclusion: the calcification of collagen with fetuin.
Joachim H Ix; Christina L Wassel; Douglas Charles Bauer; Damon Toroian; Frances A Tylavsky; Jane A Cauley; Tamara B Harris; Paul A Price; Steven R Cummings; Michael G Shlipak
Fetuin-A and BMD in older persons: the Health Aging and Body Composition (Health ABC) study.

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All Publications

2011: Po-Yu Chen; Damon Toroian; Paul A Price; Joanna McKittrick
Minerals form a continuum phase in mature cancellous bone.
Calcified tissue international 2011;88(5):351-61.
2009: Paul A Price; Damon Toroian; Joo Eun Lim
Mineralization by inhibitor exclusion: the calcification of collagen with fetuin.
The Journal of biological chemistry 2009;284(25):17092-101.
2009: Joachim H Ix; Christina L Wassel; Douglas Charles Bauer; Damon Toroian; Frances A Tylavsky; Jane A Cauley; Tamara B Harris; Paul A Price; Steven R Cummings; Michael G Shlipak
Fetuin-A and BMD in older persons: the Health Aging and Body Composition (Health ABC) study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(3):514-21.
2009: Paul A Price; Damon Toroian; Wai Si Chan
Tissue-nonspecific alkaline phosphatase is required for the calcification of collagen in serum: a possible mechanism for biomineralization.
The Journal of biological chemistry 2009;284(7):4594-604.
2008: Damon Toroian; Paul A Price
The essential role of fetuin in the serum-induced calcification of collagen.
Calcified tissue international 2008;82(2):116-26.
2007: Damon Toroian; Joo Eun Lim; Paul A Price
The size exclusion characteristics of type I collagen: implications for the role of noncollagenous bone constituents in mineralization.
The Journal of biological chemistry 2007;282(31):22437-47.
2006: Christopher J O'Donnell; M Kyla Shea; Paul A Price; David R Gagnon; Peter W F Wilson; Martin G Larson; Douglas P Kiel; Udo Hoffmann; Maros Ferencik; Melvin E Clouse; Matthew K Williamson; L Adrienne Cupples; Bess Dawson-Hughes; Sarah L Booth
Matrix Gla protein is associated with risk factors for atherosclerosis but not with coronary artery calcification.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2769-74.
2006: Paul A Price; A M Roublick; Matthew K Williamson
Artery calcification in uremic rats is increased by a low protein diet and prevented by treatment with ibandronate.
Kidney international 2006;70(9):1577-83.
2006: Vincent Laizé; Carla S B Viegas; Paul A Price; M Leonor Cancela
Identification of an osteocalcin isoform in fish with a large acidic prodomain.
The Journal of biological chemistry 2006;281(22):15037-43.
2006: Nicholas J Hamlin; K G Ong; Paul A Price
A serum factor that recalcifies demineralized bone is conserved in bony fish and sharks but is not found in invertebrates.
Calcified tissue international 2006;78(5):326-34.
2006: Paul A Price; Wai Si Chan; Dawn M Jolson; Matthew K Williamson
The elastic lamellae of devitalized arteries calcify when incubated in serum: evidence for a serum calcification factor.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(5):1079-85.
2005: Vincent Laizé; Paulo Martel; Carla S B Viegas; Paul A Price; M Leonor Cancela
Evolution of matrix and bone gamma-carboxyglutamic acid proteins in vertebrates.
The Journal of biological chemistry 2005;280(29):26659-68.
2005: Carlos Frazão; Dina C Simes; Ricardo Coelho; Dora Alves; Matthew K Williamson; Paul A Price; M Leonor Cancela; Maria Arménia Carrondo
Structural evidence of a fourth Gla residue in fish osteocalcin: biological implications.
Biochemistry 2005;44(4):1234-42.
2004: Nicholas J Hamlin; Paul A Price
Mineralization of decalcified bone occurs under cell culture conditions and requires bovine serum but not cells.
Calcified tissue international 2004;75(3):231-42.
2004: Paul A Price; Helen H June; Nicholas J Hamlin; Matthew K Williamson
Evidence for a serum factor that initiates the re-calcification of demineralized bone.
The Journal of biological chemistry 2004;279(18):19169-80.
2004: Dina C Simes; Matthew K Williamson; B J Schaff; Paulo J Gavaia; P M Ingleton; Paul A Price; M Leonor Cancela
Characterization of osteocalcin (BGP) and matrix Gla protein (MGP) fish specific antibodies: validation for immunodetection studies in lower vertebrates.
Calcified tissue international 2004;74(2):170-80.
2004: Paul A Price; Matthew K Williamson; Thao Minh Thi Nguyen; Truclinh N Than
Serum levels of the fetuin-mineral complex correlate with artery calcification in the rat.
The Journal of biological chemistry 2004;279(3):1594-600.
2003: Paul A Price; Joo Eun Lim
The inhibition of calcium phosphate precipitation by fetuin is accompanied by the formation of a fetuin-mineral complex.
The Journal of biological chemistry 2003;278(24):22144-52.
2003: Paul A Price; Thao Minh Thi Nguyen; Matthew K Williamson
Biochemical characterization of the serum fetuin-mineral complex.
The Journal of biological chemistry 2003;278(24):22153-60.
2003: Dina C Simes; Matthew K Williamson; JB Ortiz-Delgado; Carla S B Viegas; Paul A Price; M Leonor Cancela
Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(2):244-59.
2002: Paul A Price; N Omid; T N Than; Matthew K Williamson
The amino bisphosphonate ibandronate prevents calciphylaxis in the rat at doses that inhibit bone resorption.
Calcified tissue international 2002;71(4):356-63.
2002: Paul A Price; Helen H June; Jessica R Buckley; Matthew K Williamson
SB 242784, a selective inhibitor of the osteoclastic V-H+ATPase, inhibits arterial calcification in the rat.
Circulation research 2002;91(6):547-52.
2002: Paul A Price; Jeffrey M Caputo; Matthew K Williamson
Bone origin of the serum complex of calcium, phosphate, fetuin, and matrix Gla protein: biochemical evidence for the cancellous bone-remodeling compartment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(7):1171-9.
2002: Paul A Price; Gethin R Thomas; Aaron W Pardini; William F Figueira; Jeffrey M Caputo; Matthew K Williamson
Discovery of a high molecular weight complex of calcium, phosphate, fetuin, and matrix gamma-carboxyglutamic acid protein in the serum of etidronate-treated rats.
The Journal of biological chemistry 2002;277(6):3926-34.
2001: Paul A Price; Jessica R Buckley; Matthew K Williamson
The amino bisphosphonate ibandronate prevents vitamin D toxicity and inhibits vitamin D-induced calcification of arteries, cartilage, lungs and kidneys in rats.
The Journal of nutrition 2001;131(11):2910-5.
2001: Paul A Price; Helen H June; Jessica R Buckley; Matthew K Williamson
Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(10):1610-6.
2001: M Leonor Cancela; Marc Ohresser; J P Reia; Carla S B Viegas; Matthew K Williamson; Paul A Price
Matrix Gla protein in Xenopus laevis: molecular cloning, tissue distribution, and evolutionary considerations.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(9):1611-21.
2001: Paul A Price; SA Faus; Matthew K Williamson
Bisphosphonates alendronate and ibandronate inhibit artery calcification at doses comparable to those that inhibit bone resorption.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(5):817-24.
2000: Paul A Price; SA Faus; Matthew K Williamson
Warfarin-induced artery calcification is accelerated by growth and vitamin D.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):317-27.
1998: Paul A Price; SA Faus; Matthew K Williamson
Warfarin causes rapid calcification of the elastic lamellae in rat arteries and heart valves.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(9):1400-7.
1997: M Leonor Cancela; B Hu; Paul A Price
Effect of cell density and growth factors on matrix GLA protein expression by normal rat kidney cells.
Journal of cellular physiology 1997;171(2):125-34.
1997: R Baumgrass; Matthew K Williamson; Paul A Price
Identification of peptide fragments generated by digestion of bovine and human osteocalcin with the lysosomal proteinases cathepsin B, D, L, H, and S.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(3):447-55.
1996: B Hu; K Trinh; W F Figueira; Paul A Price
Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family.
The Journal of biological chemistry 1996;271(32):19415-20.
1995: B Hu; L Coulson; B Moyer; Paul A Price
Isolation and molecular cloning of a novel bone phosphoprotein related in sequence to the cystatin family of thiol protease inhibitors.
The Journal of biological chemistry 1995;270(1):431-6.
1994: J R Cairns; Paul A Price
Direct demonstration that the vitamin K-dependent bone Gla protein is incompletely gamma-carboxylated in humans.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(12):1989-97.
1994: Paul A Price; J S Rice; Matthew K Williamson
Conserved phosphorylation of serines in the Ser-X-Glu/Ser(P) sequences of the vitamin K-dependent matrix Gla protein from shark, lamb, rat, cow, and human.
Protein science : a publication of the Protein Society 1994;3(5):822-30.
1994: M L Cancela; Matthew K Williamson; Paul A Price
The putative RGD-dependent cell adhesion activity of matrix Gla protein is due to higher molecular weight contaminants.
The Journal of biological chemistry 1994;269(16):12185-9.
1994: J S Rice; Matthew K Williamson; Paul A Price
Isolation and sequence of the vitamin K-dependent matrix Gla protein from the calcified cartilage of the soupfin shark.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(4):567-76.
1993: Paul A Price; Matthew K Williamson
Substrate recognition by the vitamin K-dependent gamma-glutamyl carboxylase: identification of a sequence homology between the carboxylase and the carboxylase recognition site in the substrate.
Protein science : a publication of the Protein Society 1993;2(11):1987-8.
1993: Stephen R Rannels; M L Cancela; E B Wolpert; Paul A Price
Matrix Gla protein mRNA expression in cultured type II pneumocytes.
The American journal of physiology 1993;265(3 Pt 1):L270-8.
1992: J S Johansen; Matthew K Williamson; J S Rice; Paul A Price
Identification of proteins secreted by human osteoblastic cells in culture.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(5):501-12.
1992: M L Cancela; Paul A Price
Retinoic acid induces matrix Gla protein gene expression in human cells.
Endocrinology 1992;130(1):102-8.
1991: J R Cairns; Matthew K Williamson; Paul A Price
Direct identification of gamma-carboxyglutamic acid in the sequencing of vitamin K-dependent proteins.
Analytical biochemistry 1991;199(1):93-7.
1991: J E Hale; Matthew K Williamson; Paul A Price
Carboxyl-terminal proteolytic processing of matrix Gla protein.
The Journal of biological chemistry 1991;266(31):21145-9.
1990: L Cancela; C L Hsieh; U Francke; Paul A Price
Molecular structure, chromosome assignment, and promoter organization of the human matrix Gla protein gene.
The Journal of biological chemistry 1990;265(25):15040-8.
1989: G Theofan; Paul A Price
Bone Gla protein messenger ribonucleic acid is regulated by both 1,25-dihydroxyvitamin D3 and 3',5'-cyclic adenosine monophosphate in rat osteosarcoma cells.
Molecular endocrinology (Baltimore, Md.) 1989;3(1):36-43.
1988: J D Fraser; Paul A Price
Lung, heart, and kidney express high levels of mRNA for the vitamin K-dependent matrix Gla protein. Implications for the possible functions of matrix Gla protein and for the tissue distribution of the gamma-carboxylase.
The Journal of biological chemistry 1988;263(23):11033-6.
1988: J E Hale; J D Fraser; Paul A Price
The identification of matrix Gla protein in cartilage.
The Journal of biological chemistry 1988;263(12):5820-4.
1988: J D Fraser; Y Otawara; Paul A Price
1,25-Dihydroxyvitamin D3 stimulates the synthesis of matrix gamma-carboxyglutamic acid protein by osteosarcoma cells. Mutually exclusive expression of vitamin K-dependent bone proteins by clonal osteoblastic cell lines.
The Journal of biological chemistry 1988;263(2):911-6.
1987: Paul A Price; J D Fraser; G Metz-Virca
Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8335-9.
1987: L C Pan; Paul A Price
Ligand-dependent regulation of the 1,25-dihydroxyvitamin D3 receptor in rat osteosarcoma cells.
The Journal of biological chemistry 1987;262(10):4670-5.
1987: Paul A Price
Warfarin and bone: implications for rational strategies to selectively antagonize the action of vitamin K in target tissues.
Advances in experimental medicine and biology 1987;214():55-66.
1986: Y Otawara; Paul A Price
Developmental appearance of matrix GLA protein during calcification in the rat.
The Journal of biological chemistry 1986;261(23):10828-32.
1985: Paul A Price; Matthew K Williamson
Primary structure of bovine matrix Gla protein, a new vitamin K-dependent bone protein.
The Journal of biological chemistry 1985;260(28):14971-5.
1985: L C Pan; Matthew K Williamson; Paul A Price
Sequence of the precursor to rat bone gamma-carboxyglutamic acid protein that accumulates in warfarin-treated osteosarcoma cells.
The Journal of biological chemistry 1985;260(25):13398-401.
1985: L C Pan; Paul A Price
The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(18):6109-13.
1984: L C Pan; Paul A Price
The effect of transcriptional inhibitors on the bone gamma-carboxyglutamic acid protein response to 1,25-dihydroxyvitamin D3 in osteosarcoma cells.
The Journal of biological chemistry 1984;259(9):5844-7.
1984: Paul A Price; Matthew K Williamson; S A Sloper
1,25-Dihydroxyvitamin D3 increases citrate secretion from osteosarcoma cells.
The Journal of biological chemistry 1984;259(4):2537-40.
1984: Paul A Price; C Nelson; Matthew K Williamson
Chemical modification of gamma-carboxyglutamic acid, the vitamin K-dependent amino acid which binds Ca2+.
Analytical biochemistry 1984;136(1):119-26.
1983: Paul A Price; M R Urist; Y Otawara
Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone.
Biochemical and biophysical research communications 1983;117(3):765-71.
1982: Paul A Price; Matthew K Williamson; T Haba; R B Dell; W S Jee
Excessive mineralization with growth plate closure in rats on chronic warfarin treatment.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(24):7734-8.
1981: Paul A Price; Matthew K Williamson; J W Lothringer
Origin of the vitamin K-dependent bone protein found in plasma and its clearance by kidney and bone.
The Journal of biological chemistry 1981;256(24):12760-6.
1981: Paul A Price; Matthew K Williamson
Effects of warfarin on bone. Studies on the vitamin K-dependent protein of rat bone.
The Journal of biological chemistry 1981;256(24):12754-9.
1981: Paul A Price; J W Lothringer; S A Baukol; Hari Reddi
Developmental appearance of the vitamin K-dependent protein of bone during calcification. Analysis of mineralizing tissues in human, calf, and rat.
The Journal of biological chemistry 1981;256(8):3781-4.
1981: Paul A Price; S A Baukol
1,25-dihydroxyvitamin D3 increases serum levels of the vitamin K-dependent bone protein.
Biochemical and biophysical research communications 1981;99(3):928-35.
1981: Paul A Price; Matthew K Williamson; D J Epstein
Specific tritium incorporation into gamma-carboxyglutamic acid in proteins. The pH dependence of gamma-proton exchange.
The Journal of biological chemistry 1981;256(3):1172-6.
1980: Paul A Price; S A Baukol
1,25-Dihydroxyvitamin D3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells.
The Journal of biological chemistry 1980;255(24):11660-3.
1980: Paul A Price; J W Lothringer; S K Nishimoto
Absence of the vitamin K-dependent bone protein in fetal rat mineral. Evidence for another gamma-carboxyglutamic acid-containing component in bone.
The Journal of biological chemistry 1980;255(7):2938-42.