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Roger Prichard

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Chemicals & Drugs

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Hugo C Turner; Martin Walker; Thomas S Churcher; Mike Y Osei-Atweneboana; Roger K Prichard; María-Gloria Basáñez
Uncertainty surrounding projections of the long-term impact of ivermectin treatment on human onchocerciasis.
Bernadette F Ardelli; Roger K Prichard
Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin.
Ruofeng Yan; Ludmel Urdaneta-Marquez; Mary W Davey; Catherine E James; Kathy Keller; Roger K Prichard
The role of several ABC transporter genes in ivermectin resistance in Caenorhabditis elegans.

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2013: Hugo C Turner; Martin Walker; Thomas S Churcher; Mike Y Osei-Atweneboana; Roger K Prichard; María-Gloria Basáñez
Uncertainty surrounding projections of the long-term impact of ivermectin treatment on human onchocerciasis.
PLoS neglected tropical diseases 2013;7(4):e2169.
2013: Bernadette F Ardelli; Roger K Prichard
Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin.
Veterinary parasitology 2013;191(3-4):264-75.
2012: Ruofeng Yan; Ludmel Urdaneta-Marquez; Mary W Davey; Catherine E James; Kathy Keller; Roger K Prichard
The role of several ABC transporter genes in ivermectin resistance in Caenorhabditis elegans.
Veterinary parasitology 2012;190(3-4):519-29.
2012: Hugues Nana-Djeunga; F Njiokou; S D S Pion; Catherine Bourguinat; Michel Boussinesq; Jacques Gardon; Joseph Kamgno; Roger K Prichard
Single nucleotide polymorphisms in β-tubulin selected in Onchocerca volvulus following repeated ivermectin treatment: possible indication of resistance selection.
Molecular and biochemical parasitology 2012;185(1):10-8.
2012: Virginie Barrère; Laura Ceballos; Carlos E Lanusse; Laura Moreno; Luis Alvarez; Gonzalo Suarez; Roger K Prichard
Relationship between increased albendazole systemic exposure and changes in single nucleotide polymorphisms on the β-tubulin isotype 1 encoding gene in Haemonchus contortus.
Veterinary parasitology 2012;186(3-4):344-9.
2012: Mike Y Osei-Atweneboana; Roger K Prichard; Boakye A Boatin; Sara Lustigman; María-Gloria Basáñez
A research agenda for helminth diseases of humans: health research and capacity building in disease-endemic countries for helminthiases control.
PLoS neglected tropical diseases 2012;6(4):e1602.
2012: Roger K Prichard; Banchob Sripa; Guo-Jing Yang; James S McCarthy; María-Gloria Basáñez; Boakye A Boatin; Héctor H García; Sara Lustigman
A research agenda for helminth diseases of humans: intervention for control and elimination.
PLoS neglected tropical diseases 2012;6(4):e1549.
2012: María-Gloria Basáñez; Michael D French; Manoj Gambhir; James S McCarthy; Roger K Prichard; Martin Walker; Guo-Jing Yang; Thomas S Churcher
A research agenda for helminth diseases of humans: modelling for control and elimination.
PLoS neglected tropical diseases 2012;6(4):e1548.
2012: Boakye A Boatin; Héctor H García; Andréa Gazzinelli; Warwick N Grant; James S McCarthy; Eliézer K N'Goran; Mike Y Osei-Atweneboana; Roger K Prichard; Banchob Sripa; Guo-Jing Yang; Kwablah Awadzi; Rashida M Barakat; María-Gloria Basáñez; Sara Lustigman
A research agenda for helminth diseases of humans: towards control and elimination.
PLoS neglected tropical diseases 2012;6(4):e1547.
2011: Catherine Bourguinat; Kathy Keller; Roger K Prichard; Timothy G Geary
Genetic polymorphism in Dirofilaria immitis.
Veterinary parasitology 2011;176(4):368-73.
2011: Catherine Bourguinat; Kathy Keller; Byron Blagburn; Rudolf Schenker; Timothy G Geary; Roger K Prichard
Correlation between loss of efficacy of macrocyclic lactone heartworm anthelmintics and P-glycoprotein genotype.
Veterinary parasitology 2011;176(4):374-81.
2011: Vijayaraghava T S Rao; Sean G Forrester; Kathy Keller; Roger K Prichard
Localisation of serotonin and dopamine in Haemonchus contortus.
International journal for parasitology 2011;41(2):249-54.
2011: R N Beech; P Skuce; D J Bartley; R J Martin; Roger K Prichard; J S Gilleard
Anthelmintic resistance: markers for resistance, or susceptibility?
Parasitology 2011;138(2):160-74.
2011: Mike Y Osei-Atweneboana; Kwablah Awadzi; Simon K Attah; Daniel Boakye; John O Gyapong; Roger K Prichard
Phenotypic evidence of emerging ivermectin resistance in Onchocerca volvulus.
PLoS neglected tropical diseases 2011;5(3):e998.
2010: Catherine Bourguinat; Joseph Kamgno; Michel Boussinesq; Charles Mackenzie; Roger K Prichard; Timothy G Geary
Analysis of the mdr-1 gene in patients co-infected with Onchocerca volvulus and Loa loa who experienced a post-ivermectin serious adverse event.
The American journal of tropical medicine and hygiene 2010;83(1):28-32.
2010: Timothy G Geary; Katherine Woo; James S McCarthy; Charles Mackenzie; Richard John Horton; Roger K Prichard; Nilanthi R de Silva; Piero L Olliaro; Janis K Lazdins-Helds; Dirk A Engels; Donald A Bundy
Unresolved issues in anthelmintic pharmacology for helminthiases of humans.
International journal for parasitology 2010;40(1):1-13.
2009: Bernadette F Ardelli; Laurel E Stitt; Jeffrey B Tompkins; Roger K Prichard
A comparison of the effects of ivermectin and moxidectin on the nematode Caenorhabditis elegans.
Veterinary parasitology 2009;165(1-2):96-108.
2009: Thomas S Churcher; S D S Pion; Mike Y Osei-Atweneboana; Roger K Prichard; Kwablah Awadzi; Michel Boussinesq; Richard C Collins; James A Whitworth; María-Gloria Basáñez
Identifying sub-optimal responses to ivermectin in the treatment of River Blindness.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16716-21.
2009: Vijayaraghava T S Rao; Salma Z Siddiqui; Roger K Prichard; Sean G Forrester
A dopamine-gated ion channel (HcGGR3*) from Haemonchus contortus is expressed in the cervical papillae and is associated with macrocyclic lactone resistance.
Molecular and biochemical parasitology 2009;166(1):54-61.
2009: Aissatou Diawara; Lesley J Drake; Richard R Suswillo; Jimmy Kihara; Donald A P Bundy; Marilyn E Scott; Carli Halpenny; J Russell Stothard; Roger K Prichard
Assays to detect beta-tubulin codon 200 polymorphism in Trichuris trichiura and Ascaris lumbricoides.
PLoS neglected tropical diseases 2009;3(3):e397.
2008: Catherine Bourguinat; Bernadette F Ardelli; S D S Pion; Joseph Kamgno; Jacques Gardon; Brian O L Duke; Michel Boussinesq; Roger K Prichard
P-glycoprotein-like protein, a possible genetic marker for ivermectin resistance selection in Onchocerca volvulus.
Molecular and biochemical parasitology 2008;158(2):101-11.
2008: William J Blackhall; Roger K Prichard; Robin N Beech
P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles.
Veterinary parasitology 2008;152(1-2):101-7.
2008: Maria de Lourdes Mottier; Roger K Prichard
Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortus.
Pharmacogenetics and genomics 2008;18(2):129-40.
2008: Thomas S Churcher; Anne E Schwab; Roger K Prichard; María-Gloria Basáñez
An analysis of genetic diversity and inbreeding in Wuchereria bancrofti: implications for the spread and detection of drug resistance.
PLoS neglected tropical diseases 2008;2(4):e211.
2007: Bernadette F Ardelli; Roger K Prichard
Reduced genetic variation of an Onchocerca volvulus ABC transporter gene following treatment with ivermectin.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2007;101(12):1223-32.
2007: Roger K Prichard
Ivermectin resistance and overview of the Consortium for Anthelmintic Resistance SNPs.
Expert opinion on drug discovery 2007;2(s1):S41-52.
2007: Anne E Schwab; Thomas S Churcher; Andreas Schwab; María-Gloria Basáñez; Roger K Prichard
An analysis of the population genetics of potential multi-drug resistance in Wuchereria bancrofti due to combination chemotherapy.
Parasitology 2007;134(Pt 7):1025-40.
2007: Mike Y Osei-Atweneboana; J K L Eng; Daniel Boakye; John O Gyapong; Roger K Prichard
Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study.
Lancet 2007;369(9578):2021-9.
2007: Catherine Bourguinat; S D S Pion; Joseph Kamgno; Jacques Gardon; Brian O L Duke; Michel Boussinesq; Roger K Prichard
Genetic selection of low fertile Onchocerca volvulus by ivermectin treatment.
PLoS neglected tropical diseases 2007;1(1):e72.
2007: Roger K Prichard; A Roulet
ABC transporters and beta-tubulin in macrocyclic lactone resistance: prospects for marker development.
Parasitology 2007;134(Pt 8):1123-32.
2007: Roger K Prichard
Markers for benzimidazole resistance in human parasitic nematodes?
Parasitology 2007;134(Pt 8):1087-92.
2007: Roger K Prichard; Georg von Samson-Himmelstjerna; William J Blackhall; T G Geary
Foreword: towards markers for anthelmintic resistance in helminths of importance in animal and human health.
Parasitology 2007;134(Pt 8):1073-6.
2006: J K L Eng; William J Blackhall; Mike Y Osei-Atweneboana; Catherine Bourguinat; D Galazzo; Robin N Beech; T R Unnasch; Kwablah Awadzi; George W Lubega; Roger K Prichard
Ivermectin selection on beta-tubulin: evidence in Onchocerca volvulus and Haemonchus contortus.
Molecular and biochemical parasitology 2006;150(2):229-35.
2006: Anne E Schwab; Thomas S Churcher; Andreas Schwab; María-Gloria Basáñez; Roger K Prichard
Population genetics of concurrent selection with albendazole and ivermectin or diethylcarbamazine on the possible spread of albendazole resistance in Wuchereria bancrofti.
Parasitology 2006;133(Pt 5):589-601.
2006: Bernadette F Ardelli; Silvana Guerriero; Roger K Prichard
Ivermectin imposes selection pressure on P-glycoprotein from Onchocerca volvulus: linkage disequilibrium and genotype diversity.
Parasitology 2006;132(Pt 3):375-86.
2006: Catherine Bourguinat; S D S Pion; Joseph Kamgno; Jacques Gardon; Nathalie Gardon-Wendel; Brian O L Duke; Roger K Prichard; Michel Boussinesq
Genetic polymorphism of the beta-tubulin gene of Onchocerca volvulus in ivermectin naïve patients from Cameroon, and its relationship with fertility of the worms.
Parasitology 2006;132(Pt 2):255-62.
2006: Bernadette F Ardelli; Silvana Guerriero; Roger K Prichard
Characterization of a half-size ATP-binding cassette transporter gene which may be a useful marker for ivermectin selection in Onchocerca volvulus.
Molecular and biochemical parasitology 2006;145(1):94-100.
2005: Roger K Prichard
Is anthelmintic resistance a concern for heartworm control? What can we learn from the human filariasis control programs?
Veterinary parasitology 2005;133(2-3):243-53.
2005: Bernadette F Ardelli; Silvana Guerriero; Roger K Prichard
Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein.
Molecular and biochemical parasitology 2005;143(1):58-66.
2005: Anne E Schwab; Daniel Boakye; Dominique Kyelem; Roger K Prichard
Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment.
The American journal of tropical medicine and hygiene 2005;73(2):234-8.
2005: J K L Eng; Roger K Prichard
A comparison of genetic polymorphism in populations of Onchocerca volvulus from untreated- and ivermectin-treated patients.
Molecular and biochemical parasitology 2005;142(2):193-202.
2004: Annete I Njue; Roger K Prichard
Genetic variability of glutamate-gated chloride channel genes in ivermectin-susceptible and -resistant strains of Cooperia oncophora.
Parasitology 2004;129(Pt 6):741-51.
2004: Annete I Njue; Roger K Prichard
Efficacy of ivermectin in calves against a resistant Cooperia oncophora field isolate.
Parasitology research 2004;93(5):419-22.
2004: Bernadette F Ardelli; Roger K Prichard
Identification of variant ABC-transporter genes among Onchocerca volvulus collected from ivermectin-treated and untreated patients in Ghana, West Africa.
Annals of tropical medicine and parasitology 2004;98(4):371-84.
2004: Annete I Njue; Jon Hayashi; Lyle Kinne; Xiao-Peng Feng; Roger K Prichard
Mutations in the extracellular domains of glutamate-gated chloride channel alpha3 and beta subunits from ivermectin-resistant Cooperia oncophora affect agonist sensitivity.
Journal of neurochemistry 2004;89(5):1137-47.
2004: Jie Liu; Joseph A Dent; Robin N Beech; Roger K Prichard
Genomic organization of an avermectin receptor subunit from Haemonchus contortus and expression of its putative promoter region in Caenorhabditis elegans.
Molecular and biochemical parasitology 2004;134(2):267-74.
2004: Sean G Forrester; Robin N Beech; Roger K Prichard
Agonist enhacement of macrocyclic lactone activity at a glutamate-gated chloride channel subunit from Haemonchus contortus.
Biochemical pharmacology 2004;67(6):1019-24.
2004: MB Molento; Adrián L Lifschitz; Juan M Sallovitz; Carlos E Lanusse; Roger K Prichard
Influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep.
Parasitology research 2004;92(2):121-7.
2003: Annete I Njue; Roger K Prichard
Cloning two full-length beta-tubulin isotype cDNAs from Cooperia oncophora, and screening for benzimidazole resistance-associated mutations in two isolates.
Parasitology 2003;127(Pt 6):579-88.
2003: William J Blackhall; Roger K Prichard; Robin N Beech
Selection at a gamma-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins.
Molecular and biochemical parasitology 2003;131(2):137-45.
2003: Sean G Forrester; Roger K Prichard; Joseph A Dent; Robin N Beech
Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin.
Molecular and biochemical parasitology 2003;129(1):115-21.
2003: PM Gatongi; J M Njoroge; Marilyn E Scott; S Ranjan; JM Gathuma; WK Munyua; H Cheruiyot; Roger K Prichard
Susceptibility to IVM in a field strain of Haemonchus contortus subjected to four treatments in a closed sheep-goat flock in Kenya.
Veterinary parasitology 2003;110(3-4):235-40.
2002: George W Lubega; Donosian O K Ochola; Roger K Prichard
Trypanosoma brucei: anti-tubulin antibodies specifically inhibit trypanosome growth in culture.
Experimental parasitology 2002;102(3-4):134-42.
2002: Xiao-Peng Feng; Jon Hayashi; Robin N Beech; Roger K Prichard
Study of the nematode putative GABA type-A receptor subunits: evidence for modulation by ivermectin.
Journal of neurochemistry 2002;83(4):870-8.
2002: George W Lubega; Denis K Byarugaba; Roger K Prichard
Immunization with a tubulin-rich preparation from Trypanosoma brucei confers broad protection against African trypanosomosis.
Experimental parasitology 2002;102(1):9-22.
2002: James M Smith; Roger K Prichard
Localization of p-glycoprotein mRNA in the tissues of Haemonchus contortus adult worms and its relative abundance in drug-selected and susceptible strains.
The Journal of parasitology 2002;88(3):612-20.
2002: Donasian O K Ochola; Roger K Prichard; George W Lubega
Classical ligands bind tubulin of trypanosomes and inhibit their growth in vitro.
The Journal of parasitology 2002;88(3):600-4.
2002: Sean G Forrester; Roger K Prichard; Robin N Beech
A glutamate-gated chloride channel subunit from Haemonchus contortus: expression in a mammalian cell line, ligand binding, and modulation of anthelmintic binding by glutamate.
Biochemical pharmacology 2002;63(6):1061-8.
2001: Roger K Prichard
Genetic variability following selection of Haemonchus contortus with anthelmintics.
Trends in parasitology 2001;17(9):445-53.
2001: Roger K Prichard; A Tait
The role of molecular biology in veterinary parasitology.
Veterinary parasitology 2001;98(1-3):169-94.
2001: M E Oxberry; T G Gear; Roger K Prichard
Assessment of benzimidazole binding to individual recombinant tubulin isotypes from Haemonchus contortus.
Parasitology 2001;122(Pt 6):683-7.
2001: M E Oxberry; Timothy G Geary; CA Winterrowd; Roger K Prichard
Individual expression of recombinant alpha- and beta-tubulin from Haemonchus contortus: polymerization and drug effects.
Protein expression and purification 2001;21(1):30-9.
1999: MB Molento; Roger K Prichard
Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the efficacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus).
Parasitology research 1999;85(12):1007-11.
1999: MB Molento; G T Wang; Roger K Prichard
Decreased ivermectin and moxidectin sensitivity in Haemonchus contortus selected with moxidectin over 14 generations.
Veterinary parasitology 1999;86(1):77-81.
1999: Y J Huang; Roger K Prichard
Identification and stage-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus.
Molecular and biochemical parasitology 1999;102(2):273-81.
1999: Jacques Paiement; C Leger; Paula Ribeiro; Roger K Prichard
Haemonchus contortus: effects of glutamate, ivermectin, and moxidectin on inulin uptake activity in unselected and ivermectin-selected adults.
Experimental parasitology 1999;92(3):193-8.
1999: E G Campos; M Hermes-Lima; J M Smith; Roger K Prichard
Characterisation of Fasciola hepatica cytochrome c peroxidase as an enzyme with potential antioxidant activity in vitro.
International journal for parasitology 1999;29(5):655-62.
1999: MB Molento; Carole Trudeau; Roger K Prichard; GL Zimmerman; EG Johnson; SE Marley; GA Conder
Persistent efficacy of doramectin pour-on against artificially induced infections of nematodes in cattle.
Veterinary parasitology 1999;82(4):297-303.
1999: Jacques Paiement; Roger K Prichard; Paula Ribeiro
Haemonchus contortus: characterization of a glutamate binding site in unselected and ivermectin-selected larvae and adults.
Experimental parasitology 1999;92(1):32-9.
1999: Sean G Forrester; Fadi F Hamdan; Roger K Prichard; Robin N Beech
Cloning, sequencing, and developmental expression levels of a novel glutamate-gated chloride channel homologue in the parasitic nematode Haemonchus contortus.
Biochemical and biophysical research communications 1999;254(3):529-34.
1998: William J Blackhall; H Y Liu; M Xu; Roger K Prichard; Robin N Beech
Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus.
Molecular and biochemical parasitology 1998;95(2):193-201.
1998: William J Blackhall; J F Pouliot; Roger K Prichard; Robin N Beech
Haemonchus contortus: selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains.
Experimental parasitology 1998;90(1):42-8.
1998: PM Gatongi; Roger K Prichard; S Ranjan; JM Gathuma; WK Munyua; H Cheruiyot; Marilyn E Scott
Hypobiosis of Haemonchus contortus in natural infections of sheep and goats in a semi-arid area of Kenya.
Veterinary parasitology 1998;77(1):49-61.
1998: Timothy G Geary; Susan C Nulf; Susan J Alexander-Bowman; B M Mahmoud; Roger K Prichard; RD Klein
Cloning and characterization of cDNAs encoding beta-tubulin from Dirofilaria immitis and Onchocerca volvulus.
The Journal of parasitology 1998;84(2):356-60.
1997: S Ranjan; Carole Trudeau; Roger K Prichard; J Daigneault; R S Rew
Nematode reinfection following treatment of cattle with doramectin and ivermectin.
Veterinary parasitology 1997;72(1):25-31.
1997: Roger K Prichard
Application of molecular biology in veterinary parasitology.
Veterinary parasitology 1997;71(2-3):155-75.
1997: PM Gatongi; Marilyn E Scott; S Ranjan; JM Gathuma; WK Munyua; H Cheruiyot; Roger K Prichard
Effects of three nematode anthelmintic treatment regimes on flock performance of sheep and goats under extensive management in semi-arid Kenya.
Veterinary parasitology 1997;68(4):323-36.
1997: J F Pouliot; F L'Heureux; Z Liu; Roger K Prichard; E Georges
Reversal of P-glycoprotein-associated multidrug resistance by ivermectin.
Biochemical pharmacology 1997;53(1):17-25.
1996: B Nare; G Lubega; Roger K Prichard; Elias Georges
p-Azidosalicyl-5-amino-6-phenoxybenzimidazole photolabels the N-terminal 63-103 amino acids of Haemonchus contortus beta-tubulin 1.
The Journal of biological chemistry 1996;271(15):8575-81.
1995: Carlos E Lanusse; L H Gascon; Roger K Prichard
Comparative plasma disposition kinetics of albendazole, fenbendazole, oxfendazole and their metabolites in adult sheep.
Journal of veterinary pharmacology and therapeutics 1995;18(3):196-203.
1995: Carlos E Lanusse; L H Gascon; Roger K Prichard
Influence on the antithyroid compound methimazole on the plasma disposition of fenbendazole and oxfendazole in sheep.
Research in veterinary science 1995;58(3):222-6.
1994: B Nare; Z Liu; Roger K Prichard; Elias Georges
Benzimidazoles, potent anti-mitotic drugs: substrates for the P-glycoprotein transporter in multidrug-resistant cells.
Biochemical pharmacology 1994;48(12):2215-22.
1994: Robin N Beech; Roger K Prichard; Marilyn E Scott
Genetic variability of the beta-tubulin genes in benzimidazole-susceptible and -resistant strains of Haemonchus contortus.
Genetics 1994;138(1):103-10.
1994: B Nare; Roger K Prichard; Elias Georges
Characterization of rhodamine 123 binding to P-glycoprotein in human multidrug-resistant cells.
Molecular pharmacology 1994;45(6):1145-52.
1994: G W Lubega; R D Klein; T G Geary; Roger K Prichard
Haemonchus contortus: the role of two beta-tubulin gene subfamilies in the resistance to benzimidazole anthelmintics.
Biochemical pharmacology 1994;47(9):1705-15.
1994: N I Bughio; G M Faubert; Roger K Prichard
Interaction of mebendazole with tubulin from body wall muscle, intestine, and reproductive system of Ascaris suum.
The Journal of parasitology 1994;80(1):126-32.
1993: G W Lubega; T G Geary; R D Klein; Roger K Prichard
Expression of cloned beta-tubulin genes of Haemonchus contortus in Escherichia coli: interaction of recombinant beta-tubulin with native tubulin and mebendazole.
Molecular and biochemical parasitology 1993;62(2):281-92.
1993: M Giboda; E G Campos; J M Smith; Roger K Prichard
Schistosoma mansoni: determination of the sex of cercariae using a nonradioactively labelled DNA probe.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1993;44(4):335-6.
1993: Carlos E Lanusse; Roger K Prichard
Relationship between pharmacological properties and clinical efficacy of ruminant anthelmintics.
Veterinary parasitology 1993;49(2-4):123-58.
1993: Carlos E Lanusse; B Nare; Roger K Prichard
Comparative sulphoxidation of albendazole by sheep and cattle liver microsomes and the inhibitory effect of methimazole.
Xenobiotica; the fate of foreign compounds in biological systems 1993;23(3):285-95.
1993: Carlos E Lanusse; L H Gascon; Roger K Prichard
Gastrointestinal distribution of albendazole metabolites following netobimin administration to cattle: relationship with plasma disposition kinetics.
Journal of veterinary pharmacology and therapeutics 1993;16(1):38-47.
1993: Roger K Prichard; S Ranjan
Anthelmintics.
Veterinary parasitology 1993;46(1-4):113-20.
1993: Carlos E Lanusse; Roger K Prichard
Clinical pharmacokinetics and metabolism of benzimidazole anthelmintics in ruminants.
Drug metabolism reviews 1993;25(3):235-79.
1992: Carlos E Lanusse; L Gascon; Roger K Prichard
Methimazole-mediated modulation of netobimin biotransformation in sheep: a pharmacokinetic assessment.
Journal of veterinary pharmacology and therapeutics 1992;15(3):267-74.
1992: Carlos E Lanusse; L H Gascon; S Ranjan; Roger K Prichard
Morantel tartrate release from a long-acting intraruminal device in cattle: pharmacokinetics and gastrointestinal distribution.
Journal of veterinary pharmacology and therapeutics 1992;15(2):117-23.
1992: S Ranjan; Carole Trudeau; Roger K Prichard; C Piché; S Bauck
Epidemiological study of parasite infection in a cow-calf beef herd in Quebec.
Veterinary parasitology 1992;42(3-4):281-93.
1992: Carlos E Lanusse; B Nare; L H Gascon; Roger K Prichard
Metabolism of albendazole and albendazole sulphoxide by ruminal and intestinal fluids of sheep and cattle.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(4):419-26.
1992: Carlos E Lanusse; B Nare; L H Gascon; Roger K Prichard
Bioconversion of netobimin pro-drug by gastrointestinal fluids of ruminants.
European journal of drug metabolism and pharmacokinetics 1992;17(2):121-8.
1992: B Nare; J M Smith; Roger K Prichard
Mechanisms of inactivation of Schistosoma mansoni and mammalian glutathione S-transferase activity by the antischistosomal drug oltipraz.
Biochemical pharmacology 1992;43(6):1345-51.
1992: Carlos E Lanusse; Roger K Prichard
Methimazole increases the plasma concentrations of the albendazole metabolites of netobimin in sheep.
Biopharmaceutics & drug disposition 1992;13(2):95-103.
1992: S Ranjan; Carole Trudeau; Roger K Prichard; R von Kutzleben; D Carrier
Efficacy of moxidectin against naturally acquired nematode infections in cattle.
Veterinary parasitology 1992;41(3-4):227-31.
1992: B Nare; J M Smith; Roger K Prichard
Induction of glutathione S-transferase isoenzymes in mouse liver by 5-(2-pyrazynl)-4-methyl-1,2-dithiole-3-thione (oltipraz).
Biochemical pharmacology 1992;43(4):873-9.
1992: S Guénette; Roger K Prichard; Greg Matlashewski
Identification of a novel Brugia pahangi beta-tubulin gene (beta 2) and a 22-nucleotide spliced leader sequence on beta 1-tubulin mRNA.
Molecular and biochemical parasitology 1992;50(2):275-84.
1992: Carlos E Lanusse; Roger K Prichard
Effects of methimazole on the kinetics of netobimin metabolites in cattle.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(1):115-23.
1991: B Nare; J M Smith; Roger K Prichard
Oltipraz-induced decrease in the activity of cytosolic glutathione S-transferase in Schistosoma mansoni.
International journal for parasitology 1991;21(8):919-25.
1991: N I Bughio; G M Faubert; Roger K Prichard
Identification of tubulin isoforms in different tissues of Ascaris suum using anti-tubulin monoclonal antibodies.
International journal for parasitology 1991;21(8):913-8.
1991: Carlos E Lanusse; Roger K Prichard
Enhancement of the plasma concentration of albendazole sulphoxide in sheep following coadministration of parenteral netobimin and liver oxidase inhibitors.
Research in veterinary science 1991;51(3):306-12.
1991: B Nare; J M Smith; Roger K Prichard
Differential effects of oltipraz and its oxy-analogue on the viability of Schistosoma mansoni and the activity of glutathione S-transferase.
Biochemical pharmacology 1991;42(6):1287-92.
1991: G W Lubega; Roger K Prichard
Interaction of benzimidazole anthelmintics with Haemonchus contortus tubulin: binding affinity and anthelmintic efficacy.
Experimental parasitology 1991;73(2):203-13.
1991: G W Lubega; Roger K Prichard
Beta-tubulin and benzimidazole resistance in the sheep nematode Haemonchus contortus.
Molecular and biochemical parasitology 1991;47(1):129-37.
1991: Carlos E Lanusse; Carole Trudeau; S Ranjan; Roger K Prichard
Pharmacokinetic profiles of netobimin metabolites after oral administration of zwitterion and trisamine formulations of netobimin to cattle.
Journal of veterinary pharmacology and therapeutics 1991;14(1):101-8.
1991: S Guénette; Roger K Prichard; R D Klein; Greg Matlashewski
Characterization of a beta-tubulin gene and a beta-tubulin gene products of Brugia pahangi.
Molecular and biochemical parasitology 1991;44(2):153-64.
1991: G W Lubega; Roger K Prichard
Specific interaction of benzimidazole anthelmintics with tubulin from developing stages of thiabendazole-susceptible and -resistant Haemonchus contortus.
Biochemical pharmacology 1991;41(1):93-101.
1990: Carlos E Lanusse; S Ranjan; Roger K Prichard
Comparison of pharmacokinetic variables for two injectable formulations of netobimin administered to calves.
American journal of veterinary research 1990;51(9):1459-63.
1990: Roger K Prichard
Anthelmintic resistance in nematodes: extent, recent understanding and future directions for control and research.
International journal for parasitology 1990;20(4):515-23.
1990: Carlos E Lanusse; Roger K Prichard
Pharmacokinetic behaviour of netobimin and its metabolites in sheep.
Journal of veterinary pharmacology and therapeutics 1990;13(2):170-8.
1990: B Nare; J M Smith; Roger K Prichard
Schistosoma mansoni: levels of antioxidants and resistance to oxidants increase during development.
Experimental parasitology 1990;70(4):389-97.
1990: G W Lubega; Roger K Prichard
Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus.
Molecular and biochemical parasitology 1990;38(2):221-32.
1990: G M Mkoji; J M Smith; Roger K Prichard
Effect of oltipraz on the susceptibility of adult Schistosoma mansoni to killing by mouse peritoneal exudate cells.
Parasitology research 1990;76(5):435-9.
1989: G M Mkoji; J M Smith; Roger K Prichard
Glutathione redox state, lipid peroxide levels, and activities of glutathione enzymes in oltipraz-treated adult Schistosoma mansoni.
Biochemical pharmacology 1989;38(23):4307-13.
1989: J M Smith; G M Mkoji; Roger K Prichard
Depression of hydrogen peroxide dependent killing of schistosomula in vitro by peritoneal exudate cells from Schistosoma mansoni infected mice.
The American journal of tropical medicine and hygiene 1989;40(2):186-94.
1989: L Tang; Roger K Prichard
Characterization of tubulin from Brugia malayi and Brugia pahangi.
Molecular and biochemical parasitology 1989;32(2-3):145-52.
1988: G M Mkoji; J M Smith; Roger K Prichard
Antioxidant systems in Schistosoma mansoni: evidence for their role in protection of the adult worms against oxidant killing.
International journal for parasitology 1988;18(5):667-73.
1988: G M Mkoji; J M Smith; Roger K Prichard
Antioxidant systems in Schistosoma mansoni: correlation between susceptibility to oxidant killing and the levels of scavengers of hydrogen peroxide and oxygen free radicals.
International journal for parasitology 1988;18(5):661-6.
1988: L Tang; Roger K Prichard
Comparison of the properties of tubulin from Nippostrongylus brasiliensis with mammalian brain tubulin.
Molecular and biochemical parasitology 1988;29(2-3):133-40.
1988: Roger K Prichard
Anthelmintics and control.
Veterinary parasitology 1988;27(1-2):97-109.
1988: M A Curtis; M E Rau; C E Tanner; Roger K Prichard; G M Faubert; S Olpinski; Carole Trudeau
Parasitic zoonoses in relation to fish and wildlife harvesting by Inuit communities in northern Quebec, Canada.
Arctic medical research 1988;47 Suppl 1():693-6.
1987: J M Smith; G M Mikoji; Roger K Prichard
Reduced capacity of peritoneal exudate cells for oxidative killing of Schistosoma mansoni schistosomula.
Memórias do Instituto Oswaldo Cruz 1987;82 Suppl 4():277-82.