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David Besselsen

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Laura E Wright; David G Besselsen; Jennifer B Frye; Patricia B Hoyer; Ashley L Lukefahr; Samuel L Marion; Janet L Funk
4-Vinylcyclohexene diepoxide (VCD) inhibits mammary epithelial differentiation and induces fibroadenoma formation in female Sprague Dawley rats.
Tobias Hahn; Laurence H Hurley; Hailing Lu; Disis L Mary; Tanisha Meeuwsen; Manuel L Penichet; Daniel Von-Hoff; Edwin Walker; David G Besselsen; Deborah J Bradley-Dunlop; Brook B Cole; Stephen Gately; Emmanuel T Akporiaye
The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer.
Natalia A Ignatenko; Eugene W Gerner; David G Besselsen
Defining the role of polyamines in colon carcinogenesis using mouse models.

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All Publications

2011: Laura E Wright; David G Besselsen; Jennifer B Frye; Patricia B Hoyer; Ashley L Lukefahr; Samuel L Marion; Janet L Funk
4-Vinylcyclohexene diepoxide (VCD) inhibits mammary epithelial differentiation and induces fibroadenoma formation in female Sprague Dawley rats.
Reproductive toxicology (Elmsford, N.Y.) 2011;32(1):26-32.
2011: Tobias Hahn; Laurence H Hurley; Hailing Lu; Disis L Mary; Tanisha Meeuwsen; Manuel L Penichet; Daniel Von-Hoff; Edwin Walker; David G Besselsen; Deborah J Bradley-Dunlop; Brook B Cole; Stephen Gately; Emmanuel T Akporiaye
The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer.
BMC cancer 2011;11():471.
2011: Natalia A Ignatenko; Eugene W Gerner; David G Besselsen
Defining the role of polyamines in colon carcinogenesis using mouse models.
Journal of carcinogenesis 2011;10():10.
2010: Margaret Flowers; Joyce A Schroeder; Alexander D Borowsky; David G Besselsen; Cynthia A Thomson; Ritu Pandey; Patricia A Thompson
Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice.
Carcinogenesis 2010;31(9):1642-9.
2010: Carolyn Cray; David G Besselsen; Jody L Hart; David Yoon; Marilyn Rodriguez; Julia Zaias; Norman Altman
Quantitation of acute phase proteins and protein electrophoresis in monitoring the acute inflammatory process in experimentally and naturally infected mice.
Comparative medicine 2010;60(4):263-71.
2010: Robert D Thurston; Claire B Larmonier; Pawel M Majewski; Rajalakshmy Ramalingam; Monica Midura-Kiela; Daniel Laubitz; Alain Vandewalle; David G Besselsen; Marcus Mühlbauer; Christian Jobin; Pawel Kiela; Fayez K Ghishan
Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis.
Gastroenterology 2010;138(4):1384-94, 1394.e1-2.
2009: Lisa D Beilke; Lauren M Aleksunes; Erik R Olson; David G Besselsen; Curtis D Klaassen; Katerina Dvorak; Nathan J Cherrington
Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice.
Toxicology letters 2009;188(1):38-44.
2009: Craig D Fisher; Andrew J Lickteig; Lisa M Augustine; Ronald P J Oude Elferink; David G Besselsen; Robert P Erickson; Nathan J Cherrington
Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats.
European journal of pharmacology 2009;613(1-3):119-27.
2009: Matthew P Rausch; Tobias Hahn; Lalitha Ramanathapuram; Deborah Bradley-Dunlop; Daruka Mahadevan; Melania Mercado-Pimentel; Raymond Runyan; David G Besselsen; Xiamei Zhang; H-Kam Cheung; Wen-Cherng Lee; Leona E Ling; Emmanuel T Akporiaye
An orally active small molecule TGF-beta receptor I antagonist inhibits the growth of metastatic murine breast cancer.
Anticancer research 2009;29(6):2099-109.
2009: J A Udovich; David G Besselsen; Arthur F Gmitro
Assessment of acridine orange and SYTO 16 for in vivo imaging of the peritoneal tissues in mice.
Journal of microscopy 2009;234(2):124-9.
2009: Lisa D Beilke; Lauren M Aleksunes; Ricky D Holland; David G Besselsen; Richard Beger; Curtis D Klaassen; Nathan J Cherrington
Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(5):1035-45.
2008: David G Besselsen; Melissa J Romero-Aleshire; Stephanie J Munger; Emily C Marcus; Kenneth S Henderson; April M Wagner
Embryo transfer rederivation of C.B-17/Icr-Prkdc(scid) mice experimentally infected with mouse parvovirus 1.
Comparative medicine 2008;58(4):353-9.
2008: David G Besselsen; Erin L Myers; Craig L Franklin; Scott W Korte; April M Wagner; Kenneth S Henderson; Benjamin J Weigler
Transmission probabilities of mouse parvovirus 1 to sentinel mice chronically exposed to serial dilutions of contaminated bedding.
Comparative medicine 2008;58(2):140-4.
2008: Lisa D Beilke; David G Besselsen; Quiqiong Cheng; Supriya Kulkarni; Angela L Slitt; Nathan J Cherrington
Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis.
Toxicological sciences : an official journal of the Society of Toxicology 2008;102(1):196-204.
2008: Natalia A Ignatenko; David G Besselsen; David E Stringer; Karen A Blohm-Mangone; Haiyan Cui; Eugene W Gerner
Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis.
Nutrition and cancer 2008;60 Suppl 1():30-5.
2008: David G Besselsen; Craig L Franklin; Robert S Livingston; Lela K Riley
Lurking in the shadows: emerging rodent infectious diseases.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2008;49(3):277-90.
2007: Lida P Hariri; Ziping Qiu; Alexandre R Tumlinson; David G Besselsen; Eugene W Gerner; Natalia A Ignatenko; Boris Povazay; Boris Hermann; Harald Sattmann; James McNally; Angelika Unterhuber; Wolfgang Drexler; Jennifer K Barton
Serial endoscopy in azoxymethane treated mice using ultra-high resolution optical coherence tomography.
Cancer biology & therapy 2007;6(11):1753-62.
2007: Andrew J Lickteig; Craig D Fisher; Lisa M Augustine; Lauren M Aleksunes; David G Besselsen; Angela L Slitt; José E Manautou; Nathan J Cherrington
Efflux transporter expression and acetaminophen metabolite excretion are altered in rodent models of nonalcoholic fatty liver disease.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(10):1970-8.
2007: Emmanuel T Akporiaye; Deborah Bradley-Dunlop; Sandra J Gendler; Pinku Mukherjee; Cathy S Madsen; Tobias Hahn; David G Besselsen; Sharon M Dial; Haiyan Cui; Katrina T Trevor
Characterization of the MUC1.Tg/MIN transgenic mouse as a model for studying antigen-specific immunotherapy of adenomas.
Vaccine 2007;25(39-40):6965-74.
2007: Lida P Hariri; Alexandre R Tumlinson; Norman H Wade; David G Besselsen; Urs Utzinger; Eugene W Gerner; Jennifer K Barton
Ex vivo optical coherence tomography and laser-induced fluorescence spectroscopy imaging of murine gastrointestinal tract.
Comparative medicine 2007;57(2):175-85.
2007: Harris Bernstein; Hana Holubec; Carol Bernstein; Natalia A Ignatenko; Eugene W Gerner; Katerina Dvorak; David G Besselsen; Karen A Blohm-Mangone; Jose L Padilla-Torres; Barbora Dvorakova; Harinder Garewal; Claire M Payne
Deoxycholate-induced colitis is markedly attenuated in Nos2 knockout mice in association with modulation of gene expression profiles.
Digestive diseases and sciences 2007;52(3):628-42.
2007: David G Besselsen; Michael D Becker; Kenneth S Henderson; April M Wagner; Laila A Banu; William R Shek
Temporal transmission studies of mouse parvovirus 1 in BALB/c and C.B-17/Icr-Prkdc(scid) mice.
Comparative medicine 2007;57(1):66-73.
2007: Jason A Zell; Natalia A Ignatenko; Hagit F Yerushalmi; Argyrios Ziogas; David G Besselsen; Eugene W Gerner; Hoda Anton-Culver
Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival.
International journal of cancer. Journal international du cancer 2007;120(3):459-68.
2006: Natalia A Ignatenko; Hana Holubec; David G Besselsen; Karen A Blohm-Mangone; Jose L Padilla-Torres; Raymond B Nagle; Ignacio Moreno de Alboránç; Jose M Guillen-R; Eugene W Gerner
Role of c-Myc in intestinal tumorigenesis of the ApcMin/+ mouse.
Cancer biology & therapy 2006;5(12):1658-64.
2006: Hagit F Yerushalmi; David G Besselsen; Natalia A Ignatenko; Karen A Blohm-Mangone; Jose L Padilla-Torres; David E Stringer; Jose M Guillen; Hana Holubec; Claire M Payne; Eugene W Gerner
Role of polyamines in arginine-dependent colon carcinogenesis in Apc(Min) (/+) mice.
Molecular carcinogenesis 2006;45(10):764-73.
2006: David G Besselsen; Melissa J Romero; April M Wagner; Kenneth S Henderson; Robert S Livingston
Identification of novel murine parvovirus strains by epidemiological analysis of naturally infected mice.
The Journal of general virology 2006;87(Pt 6):1543-56.
2006: James B McNally; Nathaniel D Kirkpatrick; Lida P Hariri; Alexandre R Tumlinson; David G Besselsen; Eugene W Gerner; Urs Utzinger; Jennifer K Barton
Task-based imaging of colon cancer in the Apc(Min/+) mouse model.
Applied optics 2006;45(13):3049-62.
2006: Tobias Hahn; Irene Alvarez; James J Kobie; Lalitha V Ramanathapuram; Sharon M Dial; Amy M Fulton; David G Besselsen; Edwin Walker; Emmanuel T Akporiaye
Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer.
International journal of cancer. Journal international du cancer 2006;118(9):2220-31.
2006: Harris Bernstein; Hana Holubec; Carol Bernstein; Natalia A Ignatenko; Eugene W Gerner; Katerina Dvorak; David G Besselsen; Lois Ramsey; Monique Dall'Agnol; Karen A Blohm-Mangone; Jose L Padilla-Torres; Haiyan Cui; Harinder Garewal; Claire M Payne
Unique dietary-related mouse model of colitis.
Inflammatory bowel diseases 2006;12(4):278-93.
2006: Lida P Hariri; Alexandre R Tumlinson; David G Besselsen; Urs Utzinger; Eugene W Gerner; Jennifer K Barton
Endoscopic optical coherence tomography and laser-induced fluorescence spectroscopy in a murine colon cancer model.
Lasers in surgery and medicine 2006;38(4):305-13.
2006: Hagit F Yerushalmi; David G Besselsen; Natalia A Ignatenko; Karen A Blohm-Mangone; Jose L Padilla-Torres; David E Stringer; Haiyan Cui; Hana Holubec; Claire M Payne; Eugene W Gerner
The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis.
Molecular carcinogenesis 2006;45(2):93-105.
2006: Natalia A Ignatenko; David G Besselsen; Upal K Basu Roy; David E Stringer; Karen A Blohm-Mangone; Jose L Padilla-Torres; Jose M Guillen-R; Eugene W Gerner
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis.
Nutrition and cancer 2006;56(2):172-81.
2005: Jessie K Loganbill; April M Wagner; David G Besselsen
Detection of Mycoplasma pulmonis by fluorogenic nuclease polymerase chain reaction analysis.
Comparative medicine 2005;55(5):419-24.
2005: Pawel Kiela; Anna J Midura; Nesrin Kuscuoglu; Shivanand D Jolad; Anikó M Sólyom; David G Besselsen; Barbara N Timmermann; Fayez K Ghishan
Effects of Boswellia serrata in mouse models of chemically induced colitis.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(4):G798-808.
2004: April M Wagner; Jessie K Loganbill; David G Besselsen
Detection of lactate dehydrogenase-elevating virus by use of a fluorogenic nuclease reverse transcriptase-polymerase chain reaction assay.
Comparative medicine 2004;54(3):288-92.
2003: A Uchiyama; David G Besselsen
Detection of Reovirus type 3 by use of fluorogenic nuclease reverse transcriptase polymerase chain reaction.
Laboratory animals 2003;37(4):352-9.
2003: April M Wagner; Jessie K Loganbill; David G Besselsen
Detection of sendai virus and pneumonia virus of mice by use of fluorogenic nuclease reverse transcriptase polymerase chain reaction analysis.
Comparative medicine 2003;53(2):173-7.
2003: Gregory P Boivin; Kay Washington; Kan Yang; Jerrold M Ward; Theresa P Pretlow; Robert Russell; David G Besselsen; Virginia L Godfrey; Thomas Doetschman; William F Dove; Henry C Pitot; Richard B Halberg; Steven Itzkowitz; Joanna Groden; Robert J Coffey
Pathology of mouse models of intestinal cancer: consensus report and recommendations.
Gastroenterology 2003;124(3):762-77.
2003: David G Besselsen; April M Wagner; Jessie K Loganbill
Detection of lymphocytic choriomeningitis virus by use of fluorogenic nuclease reverse transcriptase-polymerase chain reaction analysis.
Comparative medicine 2003;53(1):65-9.
2003: Eugene W Gerner; Natalia A Ignatenko; David G Besselsen
Preclinical models for chemoprevention of colon cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;163():58-71; discussion 264-6.
2002: Robert S Livingston; David G Besselsen; Earl K Steffen; Cynthia Besch-Williford; Craig L Franklin; Lela K Riley
Serodiagnosis of mice minute virus and mouse parvovirus infections in mice by enzyme-linked immunosorbent assay with baculovirus-expressed recombinant VP2 proteins.
Clinical and diagnostic laboratory immunology 2002;9(5):1025-31.
2002: Nicole L Drazenovich; Craig L Franklin; Robert S Livingston; David G Besselsen
Detection of rodent Helicobacter spp. by use of fluorogenic nuclease polymerase chain reaction assays.
Comparative medicine 2002;52(4):347-53.
2002: Melissa D Halpern; Hana Holubec; Jessica A Dominguez; Catherine S Williams; Yolanda G Meza; Debra L McWilliam; Claire M Payne; Robert S McCuskey; David G Besselsen; Bohuslav Dvorak
Up-regulation of IL-18 and IL-12 in the ileum of neonatal rats with necrotizing enterocolitis.
Pediatric research 2002;51(6):733-9.
2002: David G Besselsen; April M Wagner; Jessie K Loganbill
Detection of rodent coronaviruses by use of fluorogenic reverse transcriptase-polymerase chain reaction analysis.
Comparative medicine 2002;52(2):111-6.
2002: Ramón Tomás Sepúlveda; Shuguang Jiang; David G Besselsen; Ronald R Watson
Alcohol consumption during murine acquired immunodeficiency syndrome accentuates heart pathology due to coxsackievirus.
Alcohol and alcoholism (Oxford, Oxfordshire) 2002;37(2):157-63.
2002: Paula D Johnson; David G Besselsen
Practical aspects of experimental design in animal research.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2002;43(4):202-6.
2001: A J Redig; David G Besselsen
Detection of rodent parvoviruses by use of fluorogenic nuclease polymerase chain reaction assays.
Comparative medicine 2001;51(4):326-31.
2001: R S Wu; James J Kobie; David G Besselsen; T C Fong; V D Mack; JA McEarchern; Emmanuel T Akporiaye
Comparative analysis of IFN-gamma B7.1 and antisense TGF-beta gene transfer on the tumorigenicity of a poorly immunogenic metastatic mammary carcinoma.
Cancer immunology, immunotherapy : CII 2001;50(5):229-40.
2001: JA McEarchern; James J Kobie; V Mack; Rita S Wu; Linda C Meade-Tollin; Carlos L Arteaga; N Dumont; David G Besselsen; E Seftor; Mary J C Hendrix; Emmanuel Katsanis; Emmanuel T Akporiaye
Invasion and metastasis of a mammary tumor involves TGF-beta signaling.
International journal of cancer. Journal international du cancer 2001;91(1):76-82.
2000: David G Besselsen; April M Wagner; Jessie K Loganbill
Effect of mouse strain and age on detection of mouse parvovirus 1 by use of serologic testing and polymerase chain reaction analysis.
Comparative medicine 2000;50(5):498-502.
2000: Lon V Kendall; David G Besselsen; Lela K Riley
Fluorogenic 5' nuclease PCR (real time PCR).
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 2000;39(5):41.
2000: Daniel G Mead; Frank B Ramberg; David G Besselsen; C John Maré
Transmission of vesicular stomatitis virus from infected to noninfected black flies co-feeding on nonviremic deer mice.
Science (New York, N.Y.) 2000;287(5452):485-7.
1999: David G Besselsen; S V Gibson; Cynthia Besch-Williford; G A Purdy; R L Knowles; J E Wagner; David J Pintel; Craig L Franklin; Reuel R Hook; Lela K Riley
Natural and experimentally induced infection of Syrian hamsters with a newly recognized parvovirus.
Laboratory animal science 1999;49(3):308-12.
1999: JA McEarchern; David G Besselsen; Emmanuel T Akporiaye
Interferon gamma and antisense transforming growth factor beta transgenes synergize to enhance the immunogenicity of a murine mammary carcinoma.
Cancer immunology, immunotherapy : CII 1999;48(2-3):63-70.