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Alice Prince

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Dane Parker; Alice Prince
Epithelial uptake of flagella initiates proinflammatory signaling.
Dane Parker; Alice Prince
Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9.
Taylor Cohen; Alice Prince
Cystic fibrosis: a mucosal immunodeficiency syndrome.

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All Publications

2013: Dane Parker; Alice Prince
Epithelial uptake of flagella initiates proinflammatory signaling.
PloS one 2013;8(3):e59932.
2012: Dane Parker; Alice Prince
Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(8):4040-6.
2012: Taylor Cohen; Alice Prince
Cystic fibrosis: a mucosal immunodeficiency syndrome.
Nature medicine 2012;18(4):509-19.
2012: Dane Parker; Alice Prince
Immunopathogenesis of Staphylococcus aureus pulmonary infection.
Seminars in immunopathology 2012;34(2):281-97.
2011: Dane Parker; Alice Prince
Type I interferon response to extracellular bacteria in the airway epithelium.
Trends in immunology 2011;32(12):582-8.
2011: Grace Soong; Danielle S Ahn; Jarin Chun; Taylor Cohen; Francis J Martin; Alice Prince
Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity.
The Journal of biological chemistry 2011;286(41):35891-8.
2011: Dane Parker; Alice Prince
Innate immunity in the respiratory epithelium.
American journal of respiratory cell and molecular biology 2011;45(2):189-201.
2011: Francis J Martin; Dane Parker; Bryan S Harfenist; Grace Soong; Alice Prince
Participation of CD11c(+) leukocytes in methicillin-resistant Staphylococcus aureus clearance from the lung.
Infection and immunity 2011;79(5):1898-904.
2011: Dane Parker; Francis J Martin; Grace Soong; Bryan S Harfenist; Jorge L Aguilar; Adam J Ratner; Katherine A Fitzgerald; Christian Schindler; Alice Prince
Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract.
mBio 2011;2(3):e00016-11.
2010: Mei-Ho Lee; Carlos Arrecubieta; Francis J Martin; Alice Prince; Alain C Borczuk; Franklin D Lowy
A postinfluenza model of Staphylococcus aureus pneumonia.
The Journal of infectious diseases 2010;201(4):508-15.
2009: Jarin Chun; Alice Prince
Ca2+ signaling in airway epithelial cells facilitates leukocyte recruitment and transepithelial migration.
Journal of leukocyte biology 2009;86(5):1135-44.
2009: Dane Parker; Grace Soong; Paul Planet; Jonathan Brower; Adam J Ratner; Alice Prince
The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation.
Infection and immunity 2009;77(9):3722-30.
2009: Francis J Martin; Marisa I Gomez; Dawn M Wetzel; Guido Memmi; Maghnus O'Seaghdha; Grace Soong; Christian Schindler; Alice Prince
Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A.
The Journal of clinical investigation 2009;119(7):1931-9.
2009: Yu-Shan Hsiao; Dane Parker; Adam J Ratner; Alice Prince; Liang Tong
Crystal structures of respiratory pathogen neuraminidases.
Biochemical and biophysical research communications 2009;380(3):467-71.
2009: Jarin Chun; Alice Prince
TLR2-induced calpain cleavage of epithelial junctional proteins facilitates leukocyte transmigration.
Cell host & microbe 2009;5(1):47-58.
2008: Marisa I Gómez; Alice Prince
Airway epithelial cell signaling in response to bacterial pathogens.
Pediatric pulmonology 2008;43(1):11-9.
2007: Marisa I Gómez; Alice Prince
Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis.
Current opinion in pharmacology 2007;7(3):244-51.
2007: Valerie Waters; Marisa I Gómez; Grace Soong; Sunil Amin; Robert Ernst; Alice Prince
Immunostimulatory properties of the emerging pathogen Stenotrophomonas maltophilia.
Infection and immunity 2007;75(4):1698-703.
2006: Emily Rothbaum; Ouzama Nicholson; Alice Prince
Cerebral abscess associated with meningococcal meningitis.
The Pediatric infectious disease journal 2006;25(8):754-6.
2006: Grace Soong; Amanda Muir; Marisa I Gomez; Jonathan Waks; Bharat Reddy; Paul Planet; Pradeep K Singh; Yukihiro Kaneko; Yukihiro Kanetko; Matthew Wolfgang; Yu-Shan Hsiao; Liang Tong; Alice Prince
Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production.
The Journal of clinical investigation 2006;116(8):2297-2305.
2006: Jarin Chun; Alice Prince
Activation of Ca2+-dependent signaling by TLR2.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1330-7.
2006: Alice Prince
Flagellar activation of epithelial signaling.
American journal of respiratory cell and molecular biology 2006;34(5):548-51.
2005: Thor Wagner; Grace Soong; Sach Sokol; Lisa Saiman; Alice Prince
Effects of azithromycin on clinical isolates of Pseudomonas aeruginosa from cystic fibrosis patients.
Chest 2005;128(2):912-9.
2005: Valerie Waters; Sach Sokol; Bharat Reddy; Grace Soong; Jarin Chun; Alice Prince
The effect of cyclosporin A on airway cell proinflammatory signaling and pneumonia.
American journal of respiratory cell and molecular biology 2005;33(2):138-44.
2004: Marisa I Gómez; Aram Lee; Bharat Reddy; Amanda Muir; Grace Soong; Allyson Pitt; Ambrose Cheung; Alice Prince
Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1.
Nature medicine 2004;10(8):842-8.
2004: Amanda Muir; Grace Soong; Sach Sokol; Bharat Reddy; Marisa I Gomez; Anna van Heeckeren; Alice Prince
Toll-like receptors in normal and cystic fibrosis airway epithelial cells.
American journal of respiratory cell and molecular biology 2004;30(6):777-83.
2004: Grace Soong; Bharat Reddy; Sach Sokol; Robert Adamo; Alice Prince
TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells.
The Journal of clinical investigation 2004;113(10):1482-9.
2004: Robert Adamo; Sach Sokol; Grace Soong; Marisa I Gomez; Alice Prince
Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5.
American journal of respiratory cell and molecular biology 2004;30(5):627-34.
2002: Shahryar Saba; Grace Soong; Steven Greenberg; Alice Prince
Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways.
American journal of respiratory cell and molecular biology 2002;27(5):561-7.
2002: Ruth Bryan; Alice Prince
Bacterial-epithelial interactions.
Methods in molecular medicine 2002;70():465-78.
2002: Geoffrey Heyer; Shahryar Saba; Robert Adamo; William Rush; Grace Soong; Ambrose Cheung; Alice Prince
Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung.
Infection and immunity 2002;70(1):127-33.
2001: Deepa Rastogi; AJ Ratner; Alice Prince
Host-bacterial interactions in the initiation of inflammation.
Paediatric respiratory reviews 2001;2(3):245-52.
2001: A J Weber; Grace Soong; Ruth Bryan; Shahryar Saba; Alice Prince
Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function.
American journal of physiology. Lung cellular and molecular physiology 2001;281(1):L71-8.
2001: AJ Ratner; Ruth Bryan; A Weber; S Nguyen; D Barnes; A Pitt; Shari E Gelber; Ambrose Cheung; Alice Prince
Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells.
The Journal of biological chemistry 2001;276(22):19267-75.
2000: Sujatha Rajan; G Cacalano; Ruth Bryan; AJ Ratner; C U Sontich; A van Heerckeren; Pamela B Davis; Alice Prince
Pseudomonas aeruginosa induction of apoptosis in respiratory epithelial cells: analysis of the effects of cystic fibrosis transmembrane conductance regulator dysfunction and bacterial virulence factors.
American journal of respiratory cell and molecular biology 2000;23(3):304-12.
2000: AJ Ratner; Alice Prince
Lactoperoxidase. New recognition of an "old" enzyme in airway defenses.
American journal of respiratory cell and molecular biology 2000;22(6):642-4.
1999: Ruth Bryan; M Feldman; S C Jawetz; Sujatha Rajan; Emily DiMango; H B Tang; L Scheffler; D P Speert; Alice Prince
The effects of aerosolized dextran in a mouse model of Pseudomonas aeruginosa pulmonary infection.
The Journal of infectious diseases 1999;179(6):1449-58.
1998: Ruth Bryan; D Kube; A Perez; Pamela B Davis; Alice Prince
Overproduction of the CFTR R domain leads to increased levels of asialoGM1 and increased Pseudomonas aeruginosa binding by epithelial cells.
American journal of respiratory cell and molecular biology 1998;19(2):269-77.
1998: Emily DiMango; AJ Ratner; Ruth Bryan; Setareh Tabibi; Alice Prince
Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells.
The Journal of clinical investigation 1998;101(11):2598-605.
1998: M Feldman; Ruth Bryan; Sujatha Rajan; L Scheffler; SR Brunnert; H Tang; Alice Prince
Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infection.
Infection and immunity 1998;66(1):43-51.
1996: Lisa Saiman; F Mehar; W W Niu; H C Neu; K J Shaw; G Miller; Alice Prince
Antibiotic susceptibility of multiply resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis, including candidates for transplantation.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996;23(3):532-7.
1996: H B Tang; Emily DiMango; Ruth Bryan; M Gambello; Barbara H Iglewski; J B Goldberg; Alice Prince
Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection.
Infection and immunity 1996;64(1):37-43.
1995: Emily DiMango; H J Zar; Ruth Bryan; Alice Prince
Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8.
The Journal of clinical investigation 1995;96(5):2204-10.
1995: H Tang; M Kays; Alice Prince
Role of Pseudomonas aeruginosa pili in acute pulmonary infection.
Infection and immunity 1995;63(4):1278-85.
1995: L Imundo; Jonathan Barasch; Alice Prince; Qais Al-Awqati
Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):3019-23.
1995: H Zar; Lisa Saiman; L Quittell; Alice Prince
Binding of Pseudomonas aeruginosa to respiratory epithelial cells from patients with various mutations in the cystic fibrosis transmembrane regulator.
The Journal of pediatrics 1995;126(2):230-3.
1995: J R Rosh; H B Tang; L Mayer; Gabriel M Groisman; S K Abraham; Alice Prince
Treatment of intractable gastrointestinal manifestations of chronic granulomatous disease with cyclosporine.
The Journal of pediatrics 1995;126(1):143-5.
1993: Lisa Saiman; Alice Prince
Pseudomonas aeruginosa pili bind to asialoGM1 which is increased on the surface of cystic fibrosis epithelial cells.
The Journal of clinical investigation 1993;92(4):1875-80.
1993: Lisa Saiman; Alice Prince; W M Gersony
Pediatric infective endocarditis in the modern era.
The Journal of pediatrics 1993;122(6):847-53.
1993: R Proenca; W W Niu; G Cacalano; Alice Prince
The Pseudomonas cepacia 249 chromosomal penicillinase is a member of the AmpC family of chromosomal beta-lactamases.
Antimicrobial agents and chemotherapy 1993;37(4):667-74.
1992: Alice Prince
Adhesins and receptors of Pseudomonas aeruginosa associated with infection of the respiratory tract.
Microbial pathogenesis 1992;13(4):251-60.
1992: Lisa Saiman; G Cacalano; Dieter C Gruenert; Alice Prince
Comparison of adherence of Pseudomonas aeruginosa to respiratory epithelial cells from cystic fibrosis patients and healthy subjects.
Infection and immunity 1992;60(7):2808-14.
1992: G Cacalano; M Kays; Lisa Saiman; Alice Prince
Production of the Pseudomonas aeruginosa neuraminidase is increased under hyperosmolar conditions and is regulated by genes involved in alginate expression.
The Journal of clinical investigation 1992;89(6):1866-74.
1991: Jonathan Barasch; B Kiss; Alice Prince; Lisa Saiman; Dieter C Gruenert; Qais Al-Awqati
Defective acidification of intracellular organelles in cystic fibrosis.
Nature 1991;352(6330):70-3.
1990: Lisa Saiman; G Cacalano; Alice Prince
Pseudomonas cepacia adherence to respiratory epithelial cells is enhanced by Pseudomonas aeruginosa.
Infection and immunity 1990;58(8):2578-84.
1990: Lisa Saiman; K Ishimoto; S Lory; Alice Prince
The effect of piliation and exoproduct expression on the adherence of Pseudomonas aeruginosa to respiratory epithelial monolayers.
The Journal of infectious diseases 1990;161(3):541-8.
1989: Lisa Saiman; J Sadoff; Alice Prince
Cross-reactivity of Pseudomonas aeruginosa antipilin monoclonal antibodies with heterogeneous strains of P. aeruginosa and Pseudomonas cepacia.
Infection and immunity 1989;57(9):2764-70.
1989: Lisa Saiman; Alice Prince
Infections of the heart.
Advances in pediatric infectious diseases 1989;4():139-61.
1988: Alice Prince; M S Wood; G S Cacalano; N X Chin
Isolation and characterization of a penicillinase from Pseudomonas cepacia 249.
Antimicrobial agents and chemotherapy 1988;32(6):838-43.