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Johannes Prins

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Liza K Phillips; Johannes B Prins
Update on incretin hormones.
James L Hare; Matthew D Hordern; Rodel Leano; Johannes B Prins; Tony Stanton; Thomas H Marwick
Application of an exercise intervention on the evolution of diastolic dysfunction in patients with diabetes mellitus: efficacy and effectiveness.
Louise J Hutley; Yu-Hee Kim; Xiao Luo; Felicity S Newell; Johannes B Prins; Wenda Shurety; Charlotte H Widberg; Jonathan P Whitehead
A putative role for endogenous FGF-2 in FGF-1 mediated differentiation of human preadipocytes.

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All Publications

2011: Liza K Phillips; Johannes B Prins
Update on incretin hormones.
Annals of the New York Academy of Sciences 2011;1243():E55-74.
2011: James L Hare; Matthew D Hordern; Rodel Leano; Johannes B Prins; Tony Stanton; Thomas H Marwick
Application of an exercise intervention on the evolution of diastolic dysfunction in patients with diabetes mellitus: efficacy and effectiveness.
Circulation. Heart failure 2011;4(4):441-9.
2011: Louise J Hutley; Yu-Hee Kim; Xiao Luo; Felicity S Newell; Johannes B Prins; Wenda Shurety; Charlotte H Widberg; Jonathan P Whitehead
A putative role for endogenous FGF-2 in FGF-1 mediated differentiation of human preadipocytes.
Molecular and cellular endocrinology 2011;339(1-2):165-71.
2011: Matthew D Hordern; Thomas H Marwick; Peter Wood; Louise M Cooney; Johannes B Prins; Jeff S Coombes
Acute response of blood glucose to short-term exercise training in patients with type 2 diabetes.
Journal of science and medicine in sport / Sports Medicine Australia 2011;14(3):238-42.
2010: Abishek Iyer; David P Fairlie; Johannes B Prins; Bruce D Hammock; Lindsay Brown
Inflammatory lipid mediators in adipocyte function and obesity.
Nature reviews. Endocrinology 2010;6(2):71-82.
2010: Ayanthi A Richards; Michelle L Colgrave; Jialiang Zhang; Julie Webster; Fiona Simpson; Elaine Preston; Donna Wilks; Kyle L Hoehn; Matthew Stephenson; Graeme A MacDonald; Johannes B Prins; Gregory J Cooney; Aimin Xu; Jonathan P Whitehead
Sialic acid modification of adiponectin is not required for multimerization or secretion but determines half-life in circulation.
Molecular endocrinology (Baltimore, Md.) 2010;24(1):229-39.
2009: Ingrid J Hickman; Clair M Sullivan; Simone Flight; Catherine Campbell; Darrell H Crawford; Paul P Masci; Trisha O'Moore-Sullivan; Johannes B Prins; Graeme A MacDonald
Altered clot kinetics in patients with non-alcoholic fatty liver disease.
Annals of hepatology 2009;8(4):331-8.
2009: Hua Su; Jennifer H Gunter; Melissa de Vries; Tim Connor; Stephen Wanyonyi; Felicity S Newell; David Segal; Juan Carlos Molero; Ofer Reizes; Johannes B Prins; Louise Hutley; Ken Walder; Jonathan P Whitehead
Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity.
Biochemical and biophysical research communications 2009;386(2):351-5.
2009: Sherry Ngo; Janelle B Barry; Janelle C Nisbet; Johannes B Prins; Jonathan P Whitehead
Reduced phosphorylation of AS160 contributes to glucocorticoid-mediated inhibition of glucose uptake in human and murine adipocytes.
Molecular and cellular endocrinology 2009;302(1):33-40.
2008: Matthew D Hordern; Louise M Cooney; Elaine Beller; Johannes B Prins; Thomas H Marwick; Jeff S Coombes
Determinants of changes in blood glucose response to short-term exercise training in patients with Type 2 diabetes.
Clinical science (London, England : 1979) 2008;115(9):273-81.
2008: James A Scott; Jeff S Coombes; Johannes B Prins; Rodel L Leano; Thomas H Marwick; James E Sharman
Patients with type 2 diabetes have exaggerated brachial and central exercise blood pressure: relation to left ventricular relative wall thickness.
American journal of hypertension 2008;21(6):715-21.
2008: Liza K Phillips; Johannes B Prins
The link between abdominal obesity and the metabolic syndrome.
Current hypertension reports 2008;10(2):156-64.
2008: Ingrid J Hickman; Anthony J Russell; Johannes B Prins; Graeme A MacDonald
Should patients with type 2 diabetes and raised liver enzymes be referred for further evaluation of liver disease?
Diabetes research and clinical practice 2008;80(1):e10-2.
2008: Zia U A Mollah; Saparna Pai; Craig Moore; Brendan O'Sullivan; Matthew J Harrison; Judy Peng; Karen Phillips; Johannes B Prins; JW Cardinal; Ranjeny Thomas
Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3166-75.
2007: David W Johnson; Kirsten Armstrong; Scott B Campbell; David W Mudge; Carmel M Hawley; Jeff S Coombes; Johannes B Prins; Nicole M Isbel
Metabolic syndrome in severe chronic kidney disease: Prevalence, predictors, prognostic significance and effects of risk factor modification.
Nephrology (Carlton, Vic.) 2007;12(4):391-8.
2007: Ingrid J Hickman; Jonathan P Whitehead; Johannes B Prins; Graeme A MacDonald
Raised alanine transaminase and decreased adiponectin are features of the metabolic syndrome in patients with type 2 diabetes.
Diabetes, obesity & metabolism 2007;9(3):438-40.
2007: James E Sharman; Brian Haluska; Zhi You Fang; Johannes B Prins; Thomas H Marwick
Association of arterial wave properties and diastolic dysfunction in patients with type 2 diabetes mellitus.
The American journal of cardiology 2007;99(6):844-8.
2006: Chiew Y Wong; Nuala M Byrne; Trisha O'Moore-Sullivan; Andrew P Hills; Johannes B Prins; Thomas H Marwick
Effect of weight loss due to lifestyle intervention on subclinical cardiovascular dysfunction in obesity (body mass index >30 kg/m2).
The American journal of cardiology 2006;98(12):1593-8.
2006: Felicity S Newell; Hua Su; Hans Tornqvist; Jonathan P Whitehead; Johannes B Prins; Louise Hutley
Characterization of the transcriptional and functional effects of fibroblast growth factor-1 on human preadipocyte differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2615-7.
2006: Ayanthi A Richards; Tim Stephens; Hayley K Charlton; Alun Jones; Graeme A MacDonald; Johannes B Prins; Jonathan P Whitehead
Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: evidence for regulation of multimerization by alterations in posttranslational modifications.
Molecular endocrinology (Baltimore, Md.) 2006;20(7):1673-87.
2006: Ayanthi A Richards; Ingrid J Hickman; Amy Y-H Wang; Amanda L Jones; Felicity S Newell; Bryan J Mowry; Jonathan P Whitehead; Johannes B Prins; Graeme A MacDonald
Olanzapine treatment is associated with reduced high molecular weight adiponectin in serum: a potential mechanism for olanzapine-induced insulin resistance in patients with schizophrenia.
Journal of clinical psychopharmacology 2006;26(3):232-7.
2006: Manuela Good; Felicity M Newell; Larisa M Haupt; Jonathan P Whitehead; Louise Hutley; Johannes B Prins
TNF and TNF receptor expression and insulin sensitivity in human omental and subcutaneous adipose tissue--influence of BMI and adipose distribution.
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease 2006;3(1):26-33.
2006: Jonathan P Whitehead; Ayanthi A Richards; Ingrid J Hickman; Graeme A MacDonald; Johannes B Prins
Adiponectin--a key adipokine in the metabolic syndrome.
Diabetes, obesity & metabolism 2006;8(3):264-80.
2006: J V Warner; D R Nyholt; F Busfield; M Epstein; J Burgess; Steve Stranks; P Hill; D Perry-Keene; Diana L Learoyd; Bruce Robinson; Bin Tean Teh; Johannes B Prins; JW Cardinal
Familial isolated hyperparathyroidism is linked to a 1.7 Mb region on chromosome 2p13.3-14.
Journal of medical genetics 2006;43(3):e12.
2006: Leonie K Callaway; Johannes B Prins; Allan M Chang; H David McIntyre
The prevalence and impact of overweight and obesity in an Australian obstetric population.
The Medical journal of Australia 2006;184(2):56-9.
2005: Amy Y-H Wang; Ingrid J Hickman; Ayanthi A Richards; Jonathan P Whitehead; Johannes B Prins; Graeme A MacDonald
High molecular weight adiponectin correlates with insulin sensitivity in patients with hepatitis C genotype 3, but not genotype 1 infection.
The American journal of gastroenterology 2005;100(12):2717-23.
2005: Louise Hutley; Johannes B Prins
Fat as an endocrine organ: relationship to the metabolic syndrome.
The American journal of the medical sciences 2005;330(6):280-9.
2005: Anthony W Russell; H David McIntyre; Jonathan P Whitehead; Johannes B Prins
Adipose tissue from pregnant women with and without gestational diabetes mellitus: insulin-sensitive but resistant to hyperosomolarity.
American journal of obstetrics and gynecology 2005;193(6):2017-23.
2005: Dhrubo J Rakhit; Melodie Downey; Leanne Jeffries; Stuart Moir; Johannes B Prins; Thomas H Marwick
Screening for coronary artery disease in patients with diabetes: a Bayesian strategy of clinical risk evaluation and exercise echocardiography.
American heart journal 2005;150(5):1074-80.
2005: Zhi You Fang; James E Sharman; Johannes B Prins; Thomas H Marwick
Determinants of exercise capacity in patients with type 2 diabetes.
Diabetes care 2005;28(7):1643-8.
2005: James E Sharman; Zhi You Fang; Brian Haluska; Michael Stowasser; Johannes B Prins; Thomas H Marwick
Left ventricular mass in patients with type 2 diabetes is independently associated with central but not peripheral pulse pressure.
Diabetes care 2005;28(4):937-9.
2005: Zhi You Fang; Rebecca Schull-Meade; Rodel Leano; Philip M Mottram; Johannes B Prins; Thomas H Marwick
Screening for heart disease in diabetic subjects.
American heart journal 2005;149(2):349-54.
2005: JW Cardinal; L Bergman; N Hayward; A Sweet; J Warner; L Marks; Diana L Learoyd; Trisha Dwight; Bruce Robinson; M Epstein; M Smith; Bin Tean Teh; DP Cameron; Johannes B Prins
A report of a national mutation testing service for the MEN1 gene: clinical presentations and implications for mutation testing.
Journal of medical genetics 2005;42(1):69-74.
2004: Zhi You Fang; Johannes B Prins; Thomas H Marwick
Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications.
Endocrine reviews 2004;25(4):543-67.
2004: J Warner; M Epstein; A Sweet; D Singh; J Burgess; Steve Stranks; P Hill; D Perry-Keene; Diana L Learoyd; Bruce Robinson; P Birdsey; E Mackenzie; Bin Tean Teh; Johannes B Prins; JW Cardinal
Genetic testing in familial isolated hyperparathyroidism: unexpected results and their implications.
Journal of medical genetics 2004;41(3):155-60.
2004: Ingrid J Hickman; Julie R Jonsson; Johannes B Prins; Susan Ash; David M Purdie; Andrew D Clouston; Elizabeth E Powell
Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fasting insulin, and quality of life.
Gut 2004;53(3):413-9.
2003: Ingrid J Hickman; Elizabeth E Powell; Johannes B Prins; Andrew D Clouston; Susan Ash; David M Purdie; Julie R Jonsson
In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy.
Journal of hepatology 2003;39(6):1042-8.
2003: Louise Hutley; F M Newell; JM Joyner; S J Suchting; Adrian Herington; DP Cameron; Johannes B Prins
Effects of rosiglitazone and linoleic acid on human preadipocyte differentiation.
European journal of clinical investigation 2003;33(7):574-81.
2003: JM Joyner; Louise Hutley; Anthony W Bachmann; David Torpy; Johannes B Prins
Greater replication and differentiation of preadipocytes in inherited corticosteroid-binding globulin deficiency.
American journal of physiology. Endocrinology and metabolism 2003;284(5):E1049-54.
2003: Pascal Imbeault; Johannes B Prins; Manuela Stolic; Anthony W Russell; Trisha O'Moore-Sullivan; Jean-Pierre Després; Claude Bouchard; Angelo Tremblay
Aging per se does not influence glucose homeostasis: in vivo and in vitro evidence.
Diabetes care 2003;26(2):480-4.
2002: Ingrid J Hickman; Andrew D Clouston; Graeme A MacDonald; David M Purdie; Johannes B Prins; Susan Ash; Julie R Jonsson; Elizabeth E Powell
Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C.
Gut 2002;51(1):89-94.
2002: Joanne Voisey; Pascal Imbeault; Louise Hutley; Johannes B Prins; Angela van Daal
Body mass index-related human adipocyte agouti expression is sex-specific but not depot-specific.
Obesity research 2002;10(6):447-52.
2002: Trisha O'Moore-Sullivan; Johannes B Prins
Thiazolidinediones and type 2 diabetes: new drugs for an old disease.
The Medical journal of Australia 2002;176(8):381-6.
2001: Louise Hutley; Adrian Herington; Wenda Shurety; C Cheung; David A Vesey; DP Cameron; Johannes B Prins
Human adipose tissue endothelial cells promote preadipocyte proliferation.
American journal of physiology. Endocrinology and metabolism 2001;281(5):E1037-44.
2001: C Nugent; Johannes B Prins; Jonathan P Whitehead; D Savage; John Wentworth; V Krishna K Chatterjee; Stephen O'Rahilly
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.
Molecular endocrinology (Baltimore, Md.) 2001;15(10):1729-38.
2001: CU Niesler; Johannes B Prins; Stephen O'Rahilly; Kenneth Siddle; Montague Carl
Adipose depot-specific expression of cIAP2 in human preadipocytes and modulation of expression by serum factors and TNFalpha.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(7):1027-33.
2001: C Nugent; Johannes B Prins; Jonathan P Whitehead; John Wentworth; V Krishna K Chatterjee; Stephen O'Rahilly
Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma.
The Journal of biological chemistry 2001;276(12):9149-57.
2001: Wenda Shurety; Julia K Pagan; Johannes B Prins; Jennifer L Stow
Endocytosis of uncleaved tumor necrosis factor-alpha in macrophages.
Laboratory investigation; a journal of technical methods and pathology 2001;81(1):107-17.
2000: CU Niesler; Birgitte Uraø; Johannes B Prins; Kenneth Siddle
IGF-I inhibits apoptosis induced by serum withdrawal, but potentiates TNF-alpha-induced apoptosis, in 3T3-L1 preadipocytes.
The Journal of endocrinology 2000;167(1):165-74.
2000: JE Digby; Vivion E F Crowley; Ciaran Sewter; Jonathan P Whitehead; Johannes B Prins; Stephen O'Rahilly
Depot-related and thiazolidinedione-responsive expression of uncoupling protein 2 (UCP2) in human adipocytes.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(5):585-92.
1999: PR Faraco; EC Ledgerwood; Peter Vandenabeele; Johannes B Prins; John R Bradley
Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage.
Biochemical and biophysical research communications 1999;261(2):385-92.
1999: S J Jones; EC Ledgerwood; Johannes B Prins; J Galbraith; DR Johnson; Jordan S Pober; John R Bradley
TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1042-8.
1998: Johannes B Prins; EC Ledgerwood; P Ameloot; Peter Vandenabeele; PR Faraco; Nicholas A Bright; Stephen O'Rahilly; John R Bradley
Tumor necrosis factor-induced cytotoxicity is not related to rates of mitochondrial morphological abnormalities or autophagy-changes that can be mediated by TNFR-I or TNFR-II.
Bioscience reports 1998;18(6):329-40.
1998: EC Ledgerwood; Johannes B Prins; Nicholas A Bright; DR Johnson; K Wolfreys; Jordan S Pober; Stephen O'Rahilly; John R Bradley
Tumor necrosis factor is delivered to mitochondria where a tumor necrosis factor-binding protein is localized.
Laboratory investigation; a journal of technical methods and pathology 1998;78(12):1583-9.
1998: EC Ledgerwood; Johannes B Prins; Nicholas A Bright; DR Johnson; K Wolfreys; Jordan S Pober; Stephen O'Rahilly; John R Bradley
Tumour necrosis factor is trafficked to a mitochondrial tumour necrosis factor binding protein.
Biochemical Society transactions 1998;26(4):S316.
1998: Montague Carl; Johannes B Prins; L Sanders; J Zhang; Ciaran Sewter; JE Digby; Christopher D Byrne; Stephen O'Rahilly
Depot-related gene expression in human subcutaneous and omental adipocytes.
Diabetes 1998;47(9):1384-91.
1998: CU Niesler; Kenneth Siddle; Johannes B Prins
Human preadipocytes display a depot-specific susceptibility to apoptosis.
Diabetes 1998;47(8):1365-8.
1998: JE Digby; Montague Carl; Ciaran Sewter; L Sanders; W O Wilkison; Stephen O'Rahilly; Johannes B Prins
Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes.
Diabetes 1998;47(1):138-41.
1997: M Adams; Montague Carl; Johannes B Prins; J C Holder; S A Smith; L Sanders; JE Digby; Ciaran Sewter; Mitchell Lazar; V Krishna K Chatterjee; Stephen O'Rahilly
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.
The Journal of clinical investigation 1997;100(12):3149-53.
1997: Johannes B Prins; CU Niesler; Clay Winterford; Nicholas A Bright; Kenneth Siddle; Stephen O'Rahilly; NI Walker; DP Cameron
Tumor necrosis factor-alpha induces apoptosis of human adipose cells.
Diabetes 1997;46(12):1939-44.
1997: Montague Carl; I Sadaf Farooqi; Jonathan P Whitehead; Maria A Soos; H Rau; Nicholas J Wareham; Ciaran Sewter; JE Digby; S N Mohammed; J A Hurst; C H Cheetham; A R Earley; A H Barnett; Johannes B Prins; Stephen O'Rahilly
Congenital leptin deficiency is associated with severe early-onset obesity in humans.
Nature 1997;387(6636):903-8.
1997: Montague Carl; Johannes B Prins; L Sanders; JE Digby; Stephen O'Rahilly
Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution.
Diabetes 1997;46(3):342-7.
1995: M A McAleer; Peter C Reifsnyder; S M Palmer; M Prochazka; J M Love; J B Copeman; E E Powell; NR Rodrigues; Johannes B Prins; David V Serreze
Crosses of NOD mice with the related NON strain. A polygenic model for IDDM.
Diabetes 1995;44(10):1186-95.
1995: christopher Lord; S K Bohlander; E A Hopes; Montague Carl; NJ Hill; Johannes B Prins; R J Renjilian; Laurence B Peterson; Linda S Wicker; John A Todd
Mapping the diabetes polygene Idd3 on mouse chromosome 3 by use of novel congenic strains.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(9):563-70.
1994: Johannes B Prins; NI Walker; Clay Winterford; DP Cameron
Human adipocyte apoptosis occurs in malignancy.
Biochemical and biophysical research communications 1994;205(1):625-30.
1994: Johannes B Prins; NI Walker; Clay Winterford; DP Cameron
Apoptosis of human adipocytes in vitro.
Biochemical and biophysical research communications 1994;201(2):500-7.
1993: Michael F Seldin; Johannes B Prins; NR Rodrigues; John A Todd; Miriam H Meisler
Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 3.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4 Spec No():S47-57.
1993: John A Todd; P W Reed; Johannes B Prins; S C Bain; S M Palmer; H J Cordell; L E Pritchard; S Ghosh; Richard J Cornall; T J Aitman
Dissection of the pathophysiology of type 1 diabetes by genetic analysis.
Autoimmunity 1993;15 Suppl():16-7.
1992: M A McAleer; T J Aitman; Richard J Cornall; S Ghosh; J R Hall; C M Hearne; J M Love; Johannes B Prins; S Ramachandran; NR Rodrigues
Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrosses.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3(8):457-60.
1991: Richard J Cornall; Johannes B Prins; John A Todd; A Pressey; N H DeLarato; L S Wicker; Laurence B Peterson
Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/Ity/Bcg genes on chromosome 1.
Nature 1991;353(6341):262-5.
1991: John A Todd; T J Aitman; Richard J Cornall; S Ghosh; J R Hall; C M Hearne; A M Knight; J M Love; M A McAleer; Johannes B Prins
Genetic analysis of autoimmune type 1 diabetes mellitus in mice.
Nature 1991;351(6327):542-7.
1991: John A Todd; T J Aitman; Richard J Cornall; S Ghosh; J Hall; C M Hearne; A Knight; J Love; M A McAleer; Johannes B Prins
Genetic analysis of a complex, multifactorial disease, autoimmune type 1 (insulin-dependent) diabetes.
Research in immunology 1991;142(5-6):483.
1991: C M Hearne; M A McAleer; J M Love; T J Aitman; Richard J Cornall; S Ghosh; A M Knight; Johannes B Prins; John A Todd
Additional microsatellite markers for mouse genome mapping.
Mammalian genome : official journal of the International Mammalian Genome Society 1991;1(4):273-82.