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Cecilia Proietti

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María C Diaz Flaqué; Franco Izzo; Cecilia J Proietti; Roxana Schillaci; Rocío Vicario; Patricia V Elizalde
Progestin drives breast cancer growth by inducing p21(CIP1) expression through the assembly of a transcriptional complex among Stat3, progesterone receptor and ErbB-2.
Mercedes Tkach; Wendy Beguelin; Ernesto Gil Deza; María Celeste Díaz Flaqué; Patricia V Elizalde; Felipe G Gercovich; Pablo Guzmán; Esteban Maronna; María Florencia Mercogliano; Cecilia J Proietti; Martin Alfredo Rivas; Cinthia Rosemblit; Roxana Schillaci
p42/p44 MAPK-mediated Stat3Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth.
Mercedes Tkach; Wendy Beguelin; Juliana Cassataro; Eduardo H Charreau; Lorena Coria; María Celeste Díaz Flaqué; Patricia V Elizalde; Isabel Frahm; Cecilia J Proietti; Martin Alfredo Rivas; Cinthia Rosemblit; Roxana Schillaci
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.

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All Publications

2013: María C Diaz Flaqué; Franco Izzo; Cecilia J Proietti; Roxana Schillaci; Rocío Vicario; Patricia V Elizalde
Progestin drives breast cancer growth by inducing p21(CIP1) expression through the assembly of a transcriptional complex among Stat3, progesterone receptor and ErbB-2.
Steroids 2013;78(6):559-67.
2013: Mercedes Tkach; Wendy Beguelin; Ernesto Gil Deza; María Celeste Díaz Flaqué; Patricia V Elizalde; Felipe G Gercovich; Pablo Guzmán; Esteban Maronna; María Florencia Mercogliano; Cecilia J Proietti; Martin Alfredo Rivas; Cinthia Rosemblit; Roxana Schillaci
p42/p44 MAPK-mediated Stat3Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth.
Endocrine-related cancer 2013;20(2):197-212.
2012: Mercedes Tkach; Wendy Beguelin; Juliana Cassataro; Eduardo H Charreau; Lorena Coria; María Celeste Díaz Flaqué; Patricia V Elizalde; Isabel Frahm; Cecilia J Proietti; Martin Alfredo Rivas; Cinthia Rosemblit; Roxana Schillaci
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(3):1162-72.
2012: Laura Robaldo; María Dellafiore; Patricia V Elizalde; Franco Izzo; Javier M Montserrat; Cecilia J Proietti; Adolfo M Iribarren
Influence of conformationally restricted pyrimidines on the activity of 10-23 DNAzymes.
Bioorganic & medicinal chemistry 2012;20(8):2581-6.
2012: Roxana Schillaci; Wendy Beguelin; Florencia Cayrol; Eduardo H Charreau; María C Díaz Flaqué; Isabel Frahm; Pablo Guzmán; Esteban Maronna; Jorge Palazzi; Viviana Pineda; Cecilia J Proietti; Juan C Roa; Patricia V Elizalde
Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer.
BMC cancer 2012;12():74.
2011: Cecilia J Proietti; Wendy Béguelin; María Celeste Díaz Flaqué; Florencia Cayrol; Martin Alfredo Rivas; Mercedes Tkach; Eduardo H Charreau; Roxana Schillaci; Patricia V Elizalde
Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer.
Steroids 2011;76(4):381-92.
2010: Wendy Béguelin; María Celeste Díaz Flaqué; Cecilia J Proietti; Florencia Cayrol; Martin Alfredo Rivas; Mercedes Tkach; Cinthia Rosemblit; Johanna M Tocci; Eduardo H Charreau; Roxana Schillaci; Patricia V Elizalde
Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3.
Molecular and cellular biology 2010;30(23):5456-72.
2010: Martin Alfredo Rivas; Mercedes Tkach; Wendy Beguelin; Cecilia J Proietti; Cinthia Rosemblit; Eduardo H Charreau; Patricia V Elizalde; Roxana Schillaci
Transactivation of ErbB-2 induced by tumor necrosis factor alpha promotes NF-kappaB activation and breast cancer cell proliferation.
Breast cancer research and treatment 2010;122(1):111-24.
2009: Cecilia J Proietti; Cinthia Rosemblit; Wendy Beguelin; Martin Alfredo Rivas; María Celeste Díaz Flaqué; Eduardo H Charreau; Roxana Schillaci; Patricia V Elizalde
Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth.
Molecular and cellular biology 2009;29(5):1249-65.
2008: Martin Alfredo Rivas; Romina Carnevale; Cecilia J Proietti; Cinthia Rosemblit; Wendy Beguelin; Mariana Salatino; Eduardo H Charreau; Isabel Frahm; Sandra Sapia; Peter Brouckaert; Patricia V Elizalde; Roxana Schillaci
TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways.
Experimental cell research 2008;314(3):509-29.
2007: Romina Carnevale; Cecilia J Proietti; Mariana Salatino; Alejandro J Urtreger; Guillermo Peluffo; Dean P Edwards; Viroj Boonyaratanakornkit; Eduardo H Charreau; Elisa Bal de Kier Joffé; Roxana Schillaci; Patricia V Elizalde
Progestin effects on breast cancer cell proliferation, proteases activation, and in vivo development of metastatic phenotype all depend on progesterone receptor capacity to activate cytoplasmic signaling pathways.
Molecular endocrinology (Baltimore, Md.) 2007;21(6):1335-58.
2006: Mariana Salatino; W Beguelin; M G Peters; Romina Carnevale; Cecilia J Proietti; M D Galigniana; Cleber Giovane Vedoy; Roxana Schillaci; Eduardo H Charreau; Mari C Sogayar; Patricia V Elizalde
Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation.
Oncogene 2006;25(59):7723-39.
2006: Roxana Schillaci; Mariana Salatino; Juliana Cassataro; Cecilia J Proietti; Guillermo H Giambartolomei; Martin Alfredo Rivas; Romina Carnevale; Eduardo H Charreau; Patricia V Elizalde
Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3426-37.
2005: Cecilia J Proietti; Mariana Salatino; Cinthia Rosemblit; Romina Carnevale; Adali Pecci; Alberto R Kornblihtt; Alfredo A Molinolo; Isabel Frahm; Eduardo H Charreau; Roxana Schillaci; Patricia V Elizalde
Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells.
Molecular and cellular biology 2005;25(12):4826-40.
2004: Mariana Salatino; Roxana Schillaci; Cecilia J Proietti; Romina Carnevale; Isabel Frahm; Alfredo A Molinolo; Adolfo Iribarren; Eduardo H Charreau; Patricia V Elizalde
Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity.
Oncogene 2004;23(30):5161-74.
2004: Mariana Salatino; Roxana Schillaci; Cecilia J Proietti; Romina Carnevale; Eduardo H Charreau; Patricia V Elizalde
[Type I insulin-like growth factor receptor antisense strategies in experimental breast cancer].
Medicina 2004;64(2):129-34.
2003: Leticia Labriola; Mariana Salatino; Cecilia J Proietti; Adali Pecci; Omar A Coso; Alberto R Kornblihtt; Eduardo H Charreau; Patricia V Elizalde
Heregulin induces transcriptional activation of the progesterone receptor by a mechanism that requires functional ErbB-2 and mitogen-activated protein kinase activation in breast cancer cells.
Molecular and cellular biology 2003;23(3):1095-111.
2002: Lydia Puricelli; Cecilia J Proietti; Cecilia J Proiettii; Leticia Labriola; Mariana Salatino; Maria Balañá; Julio A Aguirre Ghiso; Ruth Lupu; Omar P Pignataro; Eduardo H Charreau; Elisa Bal de Kier Joffé; Patricia V Elizalde
Heregulin inhibits proliferation via ERKs and phosphatidyl-inositol 3-kinase activation but regulates urokinase plasminogen activator independently of these pathways in metastatic mammary tumor cells.
International journal of cancer. Journal international du cancer 2002;100(6):642-53.