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David Proud

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Christopher Rider; David Proud; Mark A Giembycz; Anna Miller-Larsson; Robert Newton
Modulation of transcriptional responses by poly(I:C) and human rhinovirus: Effect of long-acting β2-adrenoceptor agonists.
Claire E Tacon; Robert Newton; David Proud; Richard Leigh
Rhinovirus-induced MMP-9 expression is dependent on Fra-1, which is modulated by formoterol and dexamethasone.
David Proud; Claire E Tacon; Tabitha O Tonsaker; Suzanne L Traves; Brandie L Walker; Shahina Wiehler; Raza S Zaheer; Minaa A Amin; Magdalena H Hudy; Cora Kooi; Jonathan B Pelikan; Richard Leigh
Cigarette smoke modulates expression of human rhinovirus-induced airway epithelial host defense genes.

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All Publications

2013: Christopher Rider; David Proud; Mark A Giembycz; Anna Miller-Larsson; Robert Newton
Modulation of transcriptional responses by poly(I:C) and human rhinovirus: Effect of long-acting β2-adrenoceptor agonists.
European journal of pharmacology 2013;708(1-3):60-7.
2012: Claire E Tacon; Robert Newton; David Proud; Richard Leigh
Rhinovirus-induced MMP-9 expression is dependent on Fra-1, which is modulated by formoterol and dexamethasone.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(9):4621-30.
2012: David Proud; Claire E Tacon; Tabitha O Tonsaker; Suzanne L Traves; Brandie L Walker; Shahina Wiehler; Raza S Zaheer; Minaa A Amin; Magdalena H Hudy; Cora Kooi; Jonathan B Pelikan; Richard Leigh
Cigarette smoke modulates expression of human rhinovirus-induced airway epithelial host defense genes.
PloS one 2012;7(7):e40762.
2011: David Proud
Role of rhinovirus infections in asthma.
Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand 2011;29(3):201-8.
2011: David Proud; Richard Leigh
Epithelial cells and airway diseases.
Immunological reviews 2011;242(1):186-204.
2010: Raza S Zaheer; David Proud
Human rhinovirus-induced epithelial production of CXCL10 is dependent upon IFN regulatory factor-1.
American journal of respiratory cell and molecular biology 2010;43(4):413-21.
2010: Claire E Tacon; Shahina Wiehler; Neil S Holden; Robert Newton; David Proud; Richard Leigh
Human rhinovirus infection up-regulates MMP-9 production in airway epithelial cells via NF-{kappa}B.
American journal of respiratory cell and molecular biology 2010;43(2):201-9.
2010: M H Hudy; Suzanne L Traves; Shahina Wiehler; David Proud
Cigarette smoke modulates rhinovirus-induced airway epithelial cell chemokine production.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;35(6):1256-63.
2010: David Proud; D K Riker; Alkis Togias
Reproducibility of nasal allergen challenge in evaluating the efficacy of intranasal corticosteroid treatment.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(5):738-44.
2009: Sylvia M Wilson; Pamela Shen; Christopher Rider; Suzanne L Traves; David Proud; Robert Newton; Mark A Giembycz
Selective prostacyclin receptor agonism augments glucocorticoid-induced gene expression in human bronchial epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(10):6788-99.
2009: Rommy Koetzler; Raza S Zaheer; Robert Newton; David Proud
Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-kappaB pathways in rhinovirus-infected epithelial cells.
The Journal of allergy and clinical immunology 2009;124(3):551-7.
2009: Alexander Faussner; Goeran Wennerberg; Steffen Schüssler; Jens Feierler; Cornelia Seidl; Marianne Jochum; David Proud
Alanine screening of the intracellular loops of the human bradykinin B receptor--effects on receptor maintenance, G protein activation and internalization.
The FEBS journal 2009;276(13):3491-503.
2009: Raza S Zaheer; Rommy Koetzler; Neil S Holden; Shahina Wiehler; David Proud
Selective transcriptional down-regulation of human rhinovirus-induced production of CXCL10 from airway epithelial cells via the MEK1 pathway.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4854-64.
2009: Rommy Koetzler; Raza S Zaheer; Shahina Wiehler; Neil S Holden; Mark A Giembycz; David Proud
Nitric oxide inhibits human rhinovirus-induced transcriptional activation of CXCL10 in airway epithelial cells.
The Journal of allergy and clinical immunology 2009;123(1):201-208.e9.
2008: David Proud; Ronald Turner; Birgit Winther; Shahina Wiehler; Jay P Tiesman; Tim D Reichling; Kenton D Juhlin; Andy W Fulmer; Begonia Y Ho; Amy A Walanski; Cathy L Poore; Haruko Mizoguchi; Lynn Jump; Marsha L Moore; Claudine K Zukowski; Jeffrey W Clymer
Gene expression profiles during in vivo human rhinovirus infection: insights into the host response.
American journal of respiratory and critical care medicine 2008;178(9):962-8.
2008: Patrik Pipkorn; Candy Costantini; CURT REYNOLDS; Michael Wall; Margaret Drake; Alvin M Sanico; David Proud; Alkis Togias
The effects of the nasal antihistamines olopatadine and azelastine in nasal allergen provocation.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008;101(1):82-9.
2008: Lowella Heinecke; David Proud; Scherer Sanders; Robert P Schleimer; JEAN KIM
Induction of B7-H1 and B7-DC expression on airway epithelial cells by the Toll-like receptor 3 agonist double-stranded RNA and human rhinovirus infection: In vivo and in vitro studies.
The Journal of allergy and clinical immunology 2008;121(5):1155-60.
2008: Richard Leigh; Wale Oyelusi; Shahina Wiehler; Rommy Koetzler; Raza S Zaheer; Robert Newton; David Proud
Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling.
The Journal of allergy and clinical immunology 2008;121(5):1238-1245.e4.
2008: Linda M Ayer; Sylvia M Wilson; Suzanne L Traves; David Proud; Mark A Giembycz
4,5-Dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine (RO1138452) is a selective, pseudo-irreversible orthosteric antagonist at the prostacyclin (IP)-receptor expressed by human airway epithelial cells: IP-receptor-mediated inhibition of CXCL9 and CXCL10 release.
The Journal of pharmacology and experimental therapeutics 2008;324(2):815-26.
2008: Christine Lau; Xiaomin Wang; Lihua Song; Michelle North; Shahina Wiehler; David Proud; Chung-Wai Chow
Syk associates with clathrin and mediates phosphatidylinositol 3-kinase activation during human rhinovirus internalization.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):870-80.
2008: David Proud
Upper airway viral infections.
Pulmonary pharmacology & therapeutics 2008;21(3):468-73.
2007: Shahina Wiehler; David Proud
Interleukin-17A modulates human airway epithelial responses to human rhinovirus infection.
American journal of physiology. Lung cellular and molecular physiology 2007;293(2):L505-15.
2007: Suzanne L Traves; David Proud
Viral-associated exacerbations of asthma and COPD.
Current opinion in pharmacology 2007;7(3):252-8.
2007: Robert Newton; Neil S Holden; Matthew C Catley; Wale Oyelusi; Richard Leigh; David Proud; Peter J Barnes
Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors.
The Journal of pharmacology and experimental therapeutics 2007;321(2):734-42.
2006: Xiaomin Wang; Christine Lau; Shahina Wiehler; André Pow; Tony Mazzulli; Carlos Gutierrez; David Proud; Chung-Wai Chow
Syk is downstream of intercellular adhesion molecule-1 and mediates human rhinovirus activation of p38 MAPK in airway epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6859-70.
2006: David Proud; Chung-Wai Chow
Role of viral infections in asthma and chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology 2006;35(5):513-8.
2006: David Proud
The role of defensins in virus-induced asthma.
Current allergy and asthma reports 2006;6(1):81-5.
2005: Zongming Li; David Proud; Chunfen Zhang; Shahina Wiehler; Jason J McDougall
Chronic arthritis down-regulates peripheral mu-opioid receptor expression with concomitant loss of endomorphin 1 antinociception.
Arthritis and rheumatism 2005;52(10):3210-9.
2005: Jason C L Spurrell; Shahina Wiehler; Raza S Zaheer; Scherer P Sanders; David Proud
Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection.
American journal of physiology. Lung cellular and molecular physiology 2005;289(1):L85-95.
2005: David Proud
Nitric oxide and the common cold.
Current opinion in allergy and clinical immunology 2005;5(1):37-42.
2005: Alexander Faussner; Alexandra Bauer; Irina Kalatskaya; Steffen Schüssler; Cornelia Seidl; David Proud; Marianne Jochum
The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B(1) and B(2) bradykinin receptors.
The FEBS journal 2005;272(1):129-40.
2004: Irina Kalatskaya; Steffen Schüssler; Andree Blaukat; Werner Müller-Esterl; Marianne Jochum; David Proud; Alexander Faussner
Mutation of tyrosine in the conserved NPXXY sequence leads to constitutive phosphorylation and internalization, but not signaling, of the human B2 bradykinin receptor.
The Journal of biological chemistry 2004;279(30):31268-76.
2004: Scherer P Sanders; David Proud; Solbert Permutt; Edward S Siekierski; Robin Yachechko; Mark C Liu
Role of nasal nitric oxide in the resolution of experimental rhinovirus infection.
The Journal of allergy and clinical immunology 2004;113(4):697-702.
2004: David Proud; Scherer P Sanders; Shahina Wiehler
Human rhinovirus infection induces airway epithelial cell production of human beta-defensin 2 both in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4637-45.
2002: CURT REYNOLDS; Alkis Togias; David Proud
Airways hyper-responsiveness to bradykinin and methacholine: effects of inhaled fluticasone.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(8):1174-9.
2002: Lan Zhou; Arthur L Burnett; Paul L Huang; Lewis C Becker; Periannan Kuppusamy; David A Kass; J Kevin Donahue; David Proud; James Sham; Ted M Dawson; Kai Y Xu
Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle.
Biochemical and biophysical research communications 2002;294(5):1030-5.
2001: M C Subauste; D C Choi; David Proud
Transient exposure of human bronchial epithelial cells to cytokines leads to persistent increased expression of ICAM-1.
Inflammation 2001;25(6):373-80.
2001: M C Subauste; David Proud
Effects of tumor necrosis factor-alpha, epidermal growth factor and transforming growth factor-alpha on interleukin-8 production by, and human rhinovirus replication in, bronchial epithelial cells.
International immunopharmacology 2001;1(7):1229-34.
2001: Mark C Liu; David Proud; Lawrence M Lichtenstein; Walter Hubbard; Bruce S Bochner; B A Stealey; L Breslin; HUIQING XIAO; LR Freidhoff; John T Schroeder; Robert P Schleimer
Effects of prednisone on the cellular responses and release of cytokines and mediators after segmental allergen challenge of asthmatic subjects.
The Journal of allergy and clinical immunology 2001;108(1):29-38.
2001: RS Peebles; Elizabeth M Wagner; Mark C Liu; David Proud; Robert G Hamilton; Alkis Togias
Allergen-induced changes in airway responsiveness are not related to indices of airway edema.
The Journal of allergy and clinical immunology 2001;107(5):805-11.
2001: Scherer P Sanders; JEAN KIM; K R Connolly; JD Porter; Edward S Siekierski; David Proud
Nitric oxide inhibits rhinovirus-induced granulocyte macrophage colony-stimulating factor production in bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2001;24(3):317-25.
2001: RS Peebles; Robert G Hamilton; Lawrence M Lichtenstein; M Schlosberg; Mark C Liu; David Proud; Alkis Togias
Antigen-specific IgE and IgA antibodies in bronchoalveolar lavage fluid are associated with stronger antigen-induced late phase reactions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(2):239-48.
2001: Scherer P Sanders; Edward S Siekierski; S M Richards; JD Porter; Farhad Imani; David Proud
Rhinovirus infection induces expression of type 2 nitric oxide synthase in human respiratory epithelial cells in vitro and in vivo.
The Journal of allergy and clinical immunology 2001;107(2):235-43.
2000: Xinjing Wang; B Moylan; Donald A Leopold; JEAN KIM; R C Rubenstein; Alkis Togias; David Proud; Pamela L Zeitlin; Garry R Cutting
Mutation in the gene responsible for cystic fibrosis and predisposition to chronic rhinosinusitis in the general population.
JAMA : the journal of the American Medical Association 2000;284(14):1814-9.
2000: JEAN KIM; Scherer P Sanders; Edward S Siekierski; Vincenzo Casolaro; David Proud
Role of NF-kappa B in cytokine production induced from human airway epithelial cells by rhinovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3384-92.
2000: J C Kidney; David Proud
Neutrophil transmigration across human airway epithelial monolayers: mechanisms and dependence on electrical resistance.
American journal of respiratory cell and molecular biology 2000;23(3):389-95.
2000: Alvin M Sanico; Andrzej M Stanisz; T D Gleeson; Susan H Bora; David Proud; John Bienenstock; Vassilis E Koliatsos; Alkis Togias
Nerve growth factor expression and release in allergic inflammatory disease of the upper airways.
American journal of respiratory and critical care medicine 2000;161(5):1631-5.
1999: Alexander Faussner; Joan M Bathon; David Proud
Comparison of the responses of B1 and B2 kinin receptors to agonist stimulation.
Immunopharmacology 1999;45(1-3):13-20.
1999: Cristiana Stellato; Satoshi Matsukura; A Fal; J White; Lisa A Beck; David Proud; Robert P Schleimer
Differential regulation of epithelial-derived C-C chemokine expression by IL-4 and the glucocorticoid budesonide.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5624-32.
1999: Radhika Kajekar; David Proud; Allen C Myers; Sonya N Meeker; Bradley J Undem
Characterization of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea.
The Journal of pharmacology and experimental therapeutics 1999;289(2):682-7.
1999: C Rhyoo; Scherer P Sanders; Donald A Leopold; David Proud
Sinus mucosal IL-8 gene expression in chronic rhinosinusitis.
The Journal of allergy and clinical immunology 1999;103(3 Pt 1):395-400.
1999: Farhad Imani; David Proud; Diane E Griffin
Measles virus infection synergizes with IL-4 in IgE class switching.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1597-602.
1999: Fuad M Baroody; S Ford; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Relationship between histamine and physiological changes during the early response to nasal antigen provocation.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;86(2):659-68.
1999: CURT REYNOLDS; Alkis Togias; David Proud
Airway neural responses to kinins: tachyphylaxis and role of receptor subtypes.
American journal of respiratory and critical care medicine 1999;159(2):431-8.
1998: Albert John Polito; David Proud
Epithelia cells as regulators of airway inflammation.
The Journal of allergy and clinical immunology 1998;102(5):714-8.
1998: David Proud; CURT REYNOLDS; Lawrence M Lichtenstein; Anne Kagey-Sobotka; Alkis Togias
Intranasal salmeterol inhibits allergen-induced vascular permeability but not mast cell activation or cellular infiltration.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(7):868-75.
1998: Alvin M Sanico; S Atsuta; David Proud; Alkis Togias
Plasma extravasation through neuronal stimulation in human nasal mucosa in the setting of allergic rhinitis.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;84(2):537-43.
1998: K J Rager; Jeffrey O Langland; Bertram L Jacobs; David Proud; DG Marsh; Farhad Imani
Activation of antiviral protein kinase leads to immunoglobulin E class switching in human B cells.
Journal of virology 1998;72(2):1171-6.
1998: Scherer P Sanders; Edward S Siekierski; JD Porter; S M Richards; David Proud
Nitric oxide inhibits rhinovirus-induced cytokine production and viral replication in a human respiratory epithelial cell line.
Journal of virology 1998;72(2):934-42.
1998: Alexander Faussner; David Proud; M Towns; Joan M Bathon
Influence of the cytosolic carboxyl termini of human B1 and B2 kinin receptors on receptor sequestration, ligand internalization, and signal transduction.
The Journal of biological chemistry 1998;273(5):2617-23.
1998: David Proud
The kinin system in rhinitis and asthma.
Clinical reviews in allergy & immunology 1998;16(4):351-64.
1998: Alvin M Sanico; George Philip; David Proud; Robert M Naclerio; Alkis Togias
Comparison of nasal mucosal responsiveness to neuronal stimulation in non-allergic and allergic rhinitis: effects of capsaicin nasal challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(1):92-100.
1997: Alvin M Sanico; S Atsuta; David Proud; Alkis Togias
Dose-dependent effects of capsaicin nasal challenge: in vivo evidence of human airway neurogenic inflammation.
The Journal of allergy and clinical immunology 1997;100(5):632-41.
1997: Robert M Naclerio; N FRANKLIN ADKINSON; B Moylan; Fuad M Baroody; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert G Hamilton
Nasal provocation with allergen induces a secondary serum IgE antibody response.
The Journal of allergy and clinical immunology 1997;100(4):505-10.
1997: Robert M Naclerio; David Proud; B Moylan; S Balcer; LR Freidhoff; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Peter S Creticos; Robert G Hamilton; Philip S Norman
A double-blind study of the discontinuation of ragweed immunotherapy.
The Journal of allergy and clinical immunology 1997;100(3):293-300.
1997: C E Austin; Alexander Faussner; H E Robinson; S Chakravarty; D J Kyle; Joan M Bathon; David Proud
Stable expression of the human kinin B1 receptor in Chinese hamster ovary cells. Characterization of ligand binding and effector pathways.
The Journal of biological chemistry 1997;272(17):11420-5.
1997: M Desrosiers; Fuad M Baroody; David Proud; Lawrence M Lichtenstein; Anne Kagey-Sobotka; Robert M Naclerio
Treatment with hot, humid air reduces the nasal response to allergen challenge.
The Journal of allergy and clinical immunology 1997;99(1 Pt 1):77-86.
1996: Joan M Bathon; F H Chilton; Walter Hubbard; M C Towns; N J Solan; David Proud
Mechanisms of prostanoid synthesis in human synovial cells: cytokine-peptide synergism.
Inflammation 1996;20(5):537-54.
1996: Robert M Naclerio; Walter Hubbard; Lawrence M Lichtenstein; Anne Kagey-Sobotka; David Proud
Origin of late phase histamine release.
The Journal of allergy and clinical immunology 1996;98(4):721-3.
1996: Andrew R Berman; Mark C Liu; Elizabeth M Wagner; David Proud
Dissociation of bradykinin-induced plasma exudation and reactivity in the peripheral airways.
American journal of respiratory and critical care medicine 1996;154(2 Pt 1):418-23.
1996: M M Riccio; David Proud
Evidence that enhanced nasal reactivity to bradykinin in patients with symptomatic allergy is mediated by neural reflexes.
The Journal of allergy and clinical immunology 1996;97(6):1252-63.
1996: L M Gustafson; David Proud; J Owen Hendley; Frederick G Hayden; Jack M Gwaltney
Oral prednisone therapy in experimental rhinovirus infections.
The Journal of allergy and clinical immunology 1996;97(4):1009-14.
1996: Fuad M Baroody; M C Lim; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Effects of loratadine and terfenadine on the induced nasal allergic reaction.
Archives of otolaryngology--head & neck surgery 1996;122(3):309-16.
1996: M Desrosiers; David Proud; Robert M Naclerio
Lack of effect of hot, humid air on response to nasal challenge with histamine.
The Annals of otology, rhinology, and laryngology 1996;105(2):146-54.
1995: M M Riccio; CURT REYNOLDS; D W Hay; David Proud
Effects of intranasal administration of endothelin-1 to allergic and nonallergic individuals.
American journal of respiratory and critical care medicine 1995;152(6 Pt 1):1757-64.
1995: G G Weinmann; Mark C Liu; David Proud; M Weidenbach-Gerbase; Walter Hubbard; R Frank
Ozone exposure in humans: inflammatory, small and peripheral airway responses.
American journal of respiratory and critical care medicine 1995;152(4 Pt 1):1175-82.
1995: M M Riccio; David Proud; Bradley J Undem
Enhancement of afferent nerve excitability in the airways by allergic inflammation.
Pulmonary pharmacology 1995;8(4-5):181-5.
1995: Robert M Naclerio; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; M Thompson; Alkis Togias
Cold dry air-induced rhinitis: effect of inhalation and exhalation through the nose.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;79(2):467-71.
1995: David Proud; Joan M Bathon; Alkis Togias; Robert M Naclerio
Inhibition of the response to nasal provocation with bradykinin by HOE-140: efficacy and duration of action.
Canadian journal of physiology and pharmacology 1995;73(7):820-6.
1995: M C Subauste; David B Jacoby; S M Richards; David Proud
Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure.
The Journal of clinical investigation 1995;96(1):549-57.
1995: Cristiana Stellato; Lisa A Beck; G A Gorgone; David Proud; T J Schall; Santa Jeremy Ono; Lawrence M Lichtenstein; Robert P Schleimer
Expression of the chemokine RANTES by a human bronchial epithelial cell line. Modulation by cytokines and glucocorticoids.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(1):410-8.
1995: Andrew R Berman; Alkis Togias; G Skloot; David Proud
Allergen-induced hyperresponsiveness to bradykinin is more pronounced than that to methacholine.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(5):1844-52.
1994: George Philip; Fuad M Baroody; David Proud; Robert M Naclerio; Alkis Togias
The human nasal response to capsaicin.
The Journal of allergy and clinical immunology 1994;94(6 Pt 1):1035-45.
1994: Joan M Bathon; J C Croghan; Donald MacGlashan; David Proud
Bradykinin is a potent and relatively selective stimulus for cytosolic calcium elevation in human synovial cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(6):2600-8.
1994: N Takahashi; Mark C Liu; David Proud; X Y Yu; S Hasegawa; Ernst Wm Spannhake
Soluble intracellular adhesion molecule 1 in bronchoalveolar lavage fluid of allergic subjects following segmental antigen challenge.
American journal of respiratory and critical care medicine 1994;150(3):704-9.
1994: David Proud
Kinins in the pathogenesis of human airway diseases.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(8):2021-31.
1994: David Proud; M C Subauste; P E Ward
Glucocorticoids do not alter peptidase expression on a human bronchial epithelial cell line.
American journal of respiratory cell and molecular biology 1994;11(1):57-65.
1994: J Yang; Charles W Emala; Carol A Hirshman; David Proud; David B Jacoby; Michael Levine
Characterization of GTP-binding proteins coupled to inhibition of adenylyl cyclase in guinea pig tracheal epithelial cells.
American journal of respiratory cell and molecular biology 1994;10(6):665-72.
1994: David Proud; Jack M Gwaltney; J Owen Hendley; C A Dinarello; S Gillis; R P Schleimer
Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds.
The Journal of infectious diseases 1994;169(5):1007-13.
1993: David Proud; CURT REYNOLDS; J Broomfield; D W Goldman; Joan M Bathon
Bradykinin effects in guinea pig tracheal epithelial cells are mediated through a B2 kinin receptor and can be inhibited by the selective antagonist Hoe 140.
The Journal of pharmacology and experimental therapeutics 1993;264(3):1124-31.
1993: David Proud; C P Vio
Localization of immunoreactive tissue kallikrein in human trachea.
American journal of respiratory cell and molecular biology 1993;8(1):16-9.
1992: Philip S Norman; Peter S Creticos; R Tobey; David Proud; Anne Kagey-Sobotka; Deborah A Meyers; T Persson
Budesonide in grass pollen rhinitis.
Annals of allergy 1992;69(4):309-16.
1992: Fuad M Baroody; A A Cruz; Lawrence M Lichtenstein; Anne Kagey-Sobotka; David Proud; Robert M Naclerio
Intranasal beclomethasone inhibits antigen-induced nasal hyperresponsiveness to histamine.
The Journal of allergy and clinical immunology 1992;90(3 Pt 1):373-6.
1992: Joan M Bathon; David Proud; S Mizutani; P E Ward
Cultured human synovial fibroblasts rapidly metabolize kinins and neuropeptides.
The Journal of clinical investigation 1992;90(3):981-91.
1992: A A Cruz; Alkis Togias; Lawrence M Lichtenstein; Anne Kagey-Sobotka; David Proud; Robert M Naclerio
Local application of atropine attenuates the upper airway reaction to cold, dry air.
The American review of respiratory disease 1992;146(2):340-6.
1992: A M Majchel; David Proud; LR Freidhoff; Peter S Creticos; Philip S Norman; Robert M Naclerio
The nasal response to histamine challenge: effect of the pollen season and immunotherapy.
The Journal of allergy and clinical immunology 1992;90(1):85-91.
1992: David Proud; G S Bailey; Robert M Naclerio; CURT REYNOLDS; A A Cruz; Peyton A Eggleston; Lawrence M Lichtenstein; Alkis Togias
Tryptase and histamine as markers to evaluate mast cell activation during the responses to nasal challenge with allergen, cold, dry air, and hyperosmolar solutions.
The Journal of allergy and clinical immunology 1992;89(6):1098-110.
1992: A M Majchel; David Proud; Anne Kagey-Sobotka; T J Witek; Lawrence M Lichtenstein; Robert M Naclerio
Evaluation of a bedtime dose of a combination antihistamine/analgesic/decongestant product on antigen challenge the next morning.
The Laryngoscope 1992;102(3):330-4.
1992: F J Averill; Walter Hubbard; David Proud; G J Gleich; Mark C Liu
Platelet activation in the lung after antigen challenge in a model of allergic asthma.
The American review of respiratory disease 1992;145(3):571-6.
1992: M H Shin; Fuad M Baroody; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
The effect of azelastine on the early allergic response.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(2):289-95.
1992: L Churchill; B Friedman; Robert P Schleimer; David Proud
Production of granulocyte-macrophage colony-stimulating factor by cultured human tracheal epithelial cells.
Immunology 1992;75(1):189-95.
1992: Joan M Bathon; J E Croghan; D W Goldman; Donald MacGlashan; David Proud
Modulation of kinin responses in human synovium by interleukin-1.
Agents and actions. Supplements 1992;38 ( Pt 2)():16-22.
1992: Joan M Bathon; D C Manning; D W Goldman; M C Towns; David Proud
Characterization of kinin receptors on human synovial cells and upregulation of receptor number by interleukin-1.
The Journal of pharmacology and experimental therapeutics 1992;260(1):384-92.
1991: S M Walden; David Proud; Lawrence M Lichtenstein; Anne Kagey-Sobotka; Robert M Naclerio
Antigen-provoked increase in histamine reactivity. Observations on mechanisms.
The American review of respiratory disease 1991;144(3 Pt 1):642-8.
1991: M J Furin; Philip S Norman; Peter S Creticos; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Immunotherapy decreases antigen-induced eosinophil cell migration into the nasal cavity.
The Journal of allergy and clinical immunology 1991;88(1):27-32.
1991: Mark C Liu; Walter Hubbard; David Proud; B A Stealey; S J Galli; Anne Kagey-Sobotka; Eugene R Bleecker; Lawrence M Lichtenstein
Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes.
The American review of respiratory disease 1991;144(1):51-8.
1991: L Churchill; Floyd H Chilton; David Proud
Interaction of platelet-activating factor with cultured guinea pig tracheal epithelial cells.
The Biochemical journal 1991;276 ( Pt 3)():593-8.
1991: O Iliopoulos; David Proud; N FRANKLIN ADKINSON; Peter S Creticos; Philip S Norman; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Effects of immunotherapy on the early, late, and rechallenge nasal reaction to provocation with allergen: changes in inflammatory mediators and cells.
The Journal of allergy and clinical immunology 1991;87(4):855-66.
1991: A A Cruz; Alkis Togias; Lawrence M Lichtenstein; Anne Kagey-Sobotka; David Proud; Robert M Naclerio
Steroid-induced reduction of histamine release does not alter the clinical nasal response to cold, dry air.
The American review of respiratory disease 1991;143(4 Pt 1):761-5.
1991: J A Pongracic; Robert M Naclerio; CURT REYNOLDS; David Proud
A competitive kinin receptor antagonist, [DArg0, Hyp3, DPhe7]-bradykinin, does not affect the response to nasal provocation with bradykinin.
British journal of clinical pharmacology 1991;31(3):287-94.
1991: V L Cohan; Donald MacGlashan; J A Warner; Lawrence M Lichtenstein; David Proud
Mechanisms of mediator release from human skin mast cells upon stimulation by the bradykinin analog, [DArg0-Hyp3-DPhe7]bradykinin.
Biochemical pharmacology 1991;41(2):293-300.
1991: Joan M Bathon; David Proud
Bradykinin antagonists.
Annual review of pharmacology and toxicology 1991;31():129-62.
1991: A M Majchel; David Proud; Walter Hubbard; Robert M Naclerio
Histamine stimulation of the nasal mucosa does not induce prostaglandin or leukotriene generation or induce methacholine hyperresponsiveness.
International archives of allergy and applied immunology 1991;95(2-3):149-55.
1991: L Churchill; J A Pongracic; CURT REYNOLDS; Robert M Naclerio; David Proud
Pharmacology of nasal provocation with bradykinin: studies of tachyphylaxis, cyclooxygenase inhibition, alpha-adrenergic stimulation, and receptor subtype.
International archives of allergy and applied immunology 1991;95(4):322-31.
1990: O Iliopoulos; David Proud; N FRANKLIN ADKINSON; Philip S Norman; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Relationship between the early, late, and rechallenge reaction to nasal challenge with antigen: observations on the role of inflammatory mediators and cells.
The Journal of allergy and clinical immunology 1990;86(6 Pt 1):851-61.
1990: B K Flowers; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Localized antigen challenge of the nasal mucosa.
Archives of otolaryngology--head & neck surgery 1990;116(12):1407-10.
1990: Barry M Farr; Jack M Gwaltney; J Owen Hendley; Frederick G Hayden; Robert M Naclerio; T McBride; William J Doyle; J V Sorrentino; D K Riker; David Proud
A randomized controlled trial of glucocorticoid prophylaxis against experimental rhinovirus infection.
The Journal of infectious diseases 1990;162(5):1173-7.
1990: A M Majchel; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Ketotifen reduces sneezing but not histamine release following nasal challenge with antigen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1990;20(6):701-5.
1990: Z Peng; H B Lee; David Proud; Robert M Naclerio; N FRANKLIN ADKINSON
Ragweed IgE and IgG4 antibody in nasal secretions during immunotherapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1990;20(5):571-9.
1990: G Hedlin; GLENN SILBER; Robert M Naclerio; David Proud; A M Lamas; Peyton A Eggleston; N FRANKLIN ADKINSON
Comparison of the in-vivo and in-vitro response to ragweed immunotherapy in children and adults with ragweed-induced rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1990;20(5):491-500.
1990: Mark C Liu; Eugene R Bleecker; L M Lichtenstein; A Kagey-Sobotka; Y Niv; T L McLemore; Solbert Permutt; David Proud; Walter Hubbard
Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma.
The American review of respiratory disease 1990;142(1):126-32.
1990: Robert M Naclerio; Anne Kagey-Sobotka; Lawrence M Lichtenstein; LR Freidhoff; David Proud
Terfenadine, an H1 antihistamine, inhibits histamine release in vivo in the human.
The American review of respiratory disease 1990;142(1):167-71.
1990: Alkis Togias; K Lykens; Anne Kagey-Sobotka; Peyton A Eggleston; David Proud; Lawrence M Lichtenstein; Robert M Naclerio
Studies on the relationships between sensitivity to cold, dry air, hyperosmolal solutions, and histamine in the adult nose.
The American review of respiratory disease 1990;141(6):1428-33.
1990: David Proud; J Sweet; P Stein; R A Settipane; Anne Kagey-Sobotka; M H Friedlaender; Lawrence M Lichtenstein
Inflammatory mediator release on conjunctival provocation of allergic subjects with allergen.
The Journal of allergy and clinical immunology 1990;85(5):896-905.
1990: Peyton A Eggleston; Anne Kagey-Sobotka; David Proud; N FRANKLIN ADKINSON; Lawrence M Lichtenstein
Disassociation of the release of histamine and arachidonic acid metabolites from osmotically activated basophils and human lung mast cells.
The American review of respiratory disease 1990;141(4 Pt 1):960-4.
1990: B K Flowers; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
The effect of a leukotriene antagonist on the early response to antigen.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1990;102(3):219-24.
1990: David Proud; Robert M Naclerio; Jack M Gwaltney; J Owen Hendley
Kinins are generated in nasal secretions during natural rhinovirus colds.
The Journal of infectious diseases 1990;161(1):120-3.
1990: David Proud; Robert M Naclerio; Deborah A Meyers; Anne Kagey-Sobotka; Lawrence M Lichtenstein; MARTIN VALENTINE
Effects of a single-dose pretreatment with captopril on the immediate response to nasal challenge with allergen.
International archives of allergy and applied immunology 1990;93(2-3):165-70.
1989: Fuad M Baroody; David Proud; Anne Kagey-Sobotka; L Freidhoff; Philip S Norman; Lawrence M Lichtenstein; Robert M Naclerio
The effects of H1 antihistamines on the early allergic response.
Annals of allergy 1989;63(6 Pt 2):551-5.
1989: Alkis Togias; David Proud; Anne Kagey-Sobotka; L Freidhoff; Lawrence M Lichtenstein; Robert M Naclerio
In vivo and in vitro effects of antihistamines on mast cell mediator release: a potentially important property in the treatment of allergic disease.
Annals of allergy 1989;63(5):465-9.
1989: M Wachs; David Proud; Lawrence M Lichtenstein; Anne Kagey-Sobotka; Philip S Norman; Robert M Naclerio
Observations on the pathogenesis of nasal priming.
The Journal of allergy and clinical immunology 1989;84(4 Pt 1):492-501.
1989: Rebecca Bascom; U Pipkorn; David Proud; S Dunnette; G J Gleich; Lawrence M Lichtenstein; Robert M Naclerio
Major basic protein and eosinophil-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: effect of systemic corticosteroids and relationship to eosinophil influx.
The Journal of allergy and clinical immunology 1989;84(3):338-46.
1989: G Hedlin; GLENN SILBER; L Schieken; Robert M Naclerio; David Proud; Peyton A Eggleston; N FRANKLIN ADKINSON
Attenuation of allergen sensitivity early in the course of ragweed immunotherapy.
The Journal of allergy and clinical immunology 1989;84(3):390-9.
1989: Peter S Creticos; DG Marsh; David Proud; Anne Kagey-Sobotka; N FRANKLIN ADKINSON; L Friedhoff; Robert M Naclerio; Lawrence M Lichtenstein; Philip S Norman
Responses to ragweed-pollen nasal challenge before and after immunotherapy.
The Journal of allergy and clinical immunology 1989;84(2):197-205.
1989: L Churchill; Floyd H Chilton; James Resau; Rebecca Bascom; Walter Hubbard; David Proud
Cyclooxygenase metabolism of endogenous arachidonic acid by cultured human tracheal epithelial cells.
The American review of respiratory disease 1989;140(2):449-59.
1989: Joan M Bathon; David Proud; K Krackow; Fredrick M Wigley
Preincubation of human synovial cells with IL-1 modulates prostaglandin E2 release in response to bradykinin.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(2):579-86.
1989: Robert M Naclerio; David Proud; Anne Kagey-Sobotka; L Freidhoff; Philip S Norman; Lawrence M Lichtenstein
The effect of cetirizine on early allergic response.
The Laryngoscope 1989;99(6 Pt 1):596-9.
1989: I D Lawrence; J A Warner; V L Cohan; Lawrence M Lichtenstein; Anne Kagey-Sobotka; R J Vavrek; J M Stewart; David Proud
Induction of histamine release from human skin mast cells by bradykinin analogs.
Biochemical pharmacology 1989;38(2):227-33.
1989: David Proud; J O Hendley; J M Gwaltney; Robert M Naclerio
Recent studies on the rule of kinins in inflammatory diseases of human airways.
Advances in experimental medicine and biology 1989;247A():117-23.
1989: I D Lawrence; J A Warner; V L Cohan; Lawrence M Lichtenstein; Anne Kagey-Sobotka; R J Vavrek; J M Stewart; David Proud
Bradykinin analog induce histamine release from human skin mast cells.
Advances in experimental medicine and biology 1989;247A():225-9.
1988: S M Walden; David Proud; Rebecca Bascom; Lawrence M Lichtenstein; Anne Kagey-Sobotka; N FRANKLIN ADKINSON; Robert M Naclerio
Experimentally induced nasal allergic responses.
The Journal of allergy and clinical immunology 1988;81(5 Pt 2):940-9.
1988: Alkis Togias; Robert M Naclerio; David Proud; U Pipkorn; Rebecca Bascom; O Iliopoulos; Anne Kagey-Sobotka; Philip S Norman; Lawrence M Lichtenstein
Studies on the allergic and nonallergic nasal inflammation.
The Journal of allergy and clinical immunology 1988;81(5 Pt 1):782-90.
1988: David Proud; E S Siekierski; G S Bailey
Identification of human lung mast cell kininogenase as tryptase and relevance of tryptase kininogenase activity.
Biochemical pharmacology 1988;37(8):1473-80.
1988: Robert M Naclerio; David Proud; Anne Kagey-Sobotka; Lawrence M Lichtenstein; J Owen Hendley; Jack M Gwaltney
Is histamine responsible for the symptoms of rhinovirus colds? A look at the inflammatory mediators following infection.
The Pediatric infectious disease journal 1988;7(3):218-22.
1988: David Proud; CURT REYNOLDS; S Lacapra; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Robert M Naclerio
Nasal provocation with bradykinin induces symptoms of rhinitis and a sore throat.
The American review of respiratory disease 1988;137(3):613-6.
1988: Alkis Togias; David Proud; Lawrence M Lichtenstein; G K Adams; Philip S Norman; Anne Kagey-Sobotka; Robert M Naclerio
The osmolality of nasal secretions increases when inflammatory mediators are released in response to inhalation of cold, dry air.
The American review of respiratory disease 1988;137(3):625-9.
1988: GLENN SILBER; David Proud; J Warner; Robert M Naclerio; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Peyton A Eggleston
In vivo release of inflammatory mediators by hyperosmolar solutions.
The American review of respiratory disease 1988;137(3):606-12.
1988: Mark C Liu; Eugene R Bleecker; David Proud; T L McLemore; Walter Hubbard
Profiling of bisenoic prostaglandins and thromboxane B2 in bronchoalveolar fluid from the lower respiratory tract of human subjects by combined capillary gas chromatography-mass spectrometry.
Prostaglandins 1988;35(1):67-79.
1988: David Proud; A P Kaplan
Kinin formation: mechanisms and role in inflammatory disorders.
Annual review of immunology 1988;6():49-83.
1988: Robert M Naclerio; David Proud; Lawrence M Lichtenstein; Anne Kagey-Sobotka; J Owen Hendley; J Sorrentino; Jack M Gwaltney
Kinins are generated during experimental rhinovirus colds.
The Journal of infectious diseases 1988;157(1):133-42.
1987: Robert M Naclerio; Anne Kagey-Sobotka; Lawrence M Lichtenstein; Alkis Togias; O Iliopoulos; U Pipkorn; Rebecca Bascom; Philip S Norman; David Proud
Observations on nasal late phase reactions.
Immunological investigations 1987;16(8):649-85.
1987: U Pipkorn; David Proud; Lawrence M Lichtenstein; Robert P Schleimer; Stephen P Peters; N FRANKLIN ADKINSON; Anne Kagey-Sobotka; Philip S Norman; Robert M Naclerio
Effect of short-term systemic glucocorticoid treatment on human nasal mediator release after antigen challenge.
The Journal of clinical investigation 1987;80(4):957-61.