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Stanley Prusiner

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

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Wille Holger; Bian Wen; McDonald Michele; Kendall Amy; Colby David W; Bloch Lillian; Ollesch Julian; Borovinskiy Alexander L; Cohen Fred E; Prusiner Stanley B; Stubbs Gerald
Natural and synthetic prion structure from X-ray fiber diffraction.
Tamgüney Gültekin; Miller Michael W; Wolfe Lisa L; Sirochman Tracey M; Glidden David V; Palmer Christina; Lemus Azucena; DeArmond Stephen J; Prusiner Stanley B
Asymptomatic deer excrete infectious prions in faeces.
Tamgüney Gültekin; Francis Kevin P; Giles Kurt; Lemus Azucena; DeArmond Stephen J; Prusiner Stanley B
Measuring prions by bioluminescence imaging.

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All Publications

2009: Wille Holger; Bian Wen; McDonald Michele; Kendall Amy; Colby David W; Bloch Lillian; Ollesch Julian; Borovinskiy Alexander L; Cohen Fred E; Prusiner Stanley B; Stubbs Gerald
Natural and synthetic prion structure from X-ray fiber diffraction.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(40):16990-5.
2009: Tamgüney Gültekin; Miller Michael W; Wolfe Lisa L; Sirochman Tracey M; Glidden David V; Palmer Christina; Lemus Azucena; DeArmond Stephen J; Prusiner Stanley B
Asymptomatic deer excrete infectious prions in faeces.
Nature 2009;461(7263):529-32.
2009: Tamgüney Gültekin; Francis Kevin P; Giles Kurt; Lemus Azucena; DeArmond Stephen J; Prusiner Stanley B
Measuring prions by bioluminescence imaging.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(35):15002-6.
2009: Bae Sung-Hun; Legname Giuseppe; Serban Ana; Prusiner Stanley B; Wright Peter E; Dyson H Jane
Prion proteins with pathogenic and protective mutations show similar structure and dynamics.
Biochemistry 2009;48(34):8120-8.
2009: Olanow C Warren; Prusiner Stanley B
Is Parkinson's disease a prion disorder?
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12571-2.
2009: Choi Ed M; Geschwind Michael D; Deering Camille; Pomeroy Kristen; Kuo Amy; Miller Bruce L; Safar Jiri G; Prusiner Stanley B
Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease.
Laboratory investigation; a journal of technical methods and pathology 2009;89(6):624-35.
2009: Tamgüney Gültekin; Miller Michael W; Giles Kurt; Lemus Azucena; Glidden David V; DeArmond Stephen J; Prusiner Stanley B
Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein.
The Journal of general virology 2009;90(Pt 4):1035-47.
2009: Wille Holger; Shanmugam Maheswaran; Murugesu Muralee; Ollesch Julian; Stubbs Gerald; Long Jeffrey R; Safar Jiri G; Prusiner Stanley B
Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3740-5.
2009: Campana Vincenza; Zentilin Lorena; Mirabile Ilaria; Kranjc Agata; Casanova Philippe; Giacca Mauro; Prusiner Stanley B; Legname Giuseppe; Zurzolo Chiara
Development of antibody fragments for immunotherapy of prion diseases.
The Biochemical journal 2009;418(3):507-15.
2008: Godsave Susan F; Wille Holger; Kujala Pekka; Latawiec Diane; DeArmond Stephen J; Serban Ana; Prusiner Stanley B; Peters Peter J
Cryo-immunogold electron microscopy for prions: toward identification of a conversion site.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(47):12489-99.
2008: Giles Kurt; Glidden David V; Beckwith Robyn; Seoanes Rose; Peretz David; DeArmond Stephen J; Prusiner Stanley B
Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation.
PLoS pathogens 2008;4(11):e1000206.
2008: Spilman Patricia; Lessard Pierre; Sattavat Mamta; Bush Clarissa; Tousseyn Thomas; Huang Eric J; Giles Kurt; Golde Todd; Das Pritam; Fauq Abdul; Prusiner Stanley B; Dearmond Stephen J
A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(30):10595-600.
2008: Tamgüney Gültekin; Giles Kurt; Glidden David V; Lessard Pierre; Wille Holger; Tremblay Patrick; Groth Darlene F; Yehiely Fruma; Korth Carsten; Moore Richard C; Tatzelt Jörg; Rubinstein Eric; Boucheix Claude; Yang Xiaoping; Stanley Pamela; Lisanti Michael P; Dwek Raymond A; Rudd Pauline M; Moskovitz Jackob; Epstein Charles J; Cruz Tracey Dawson; Kuziel William A; Maeda Nobuyo; Sap Jan; Ashe Karen Hsiao; Carlson George A; Tesseur Ina; Wyss-Coray Tony; Mucke Lennart; Weisgraber Karl H; Mahley Robert W; Cohen Fred E; Prusiner Stanley B
Genes contributing to prion pathogenesis.
The Journal of general virology 2008;89(Pt 7):1777-88.
2008: Safar Jiri G; Lessard Pierre; Tamgüney Gültekin; Freyman Yevgeniy; Deering Camille; Letessier Frederic; Dearmond Stephen J; Prusiner Stanley B
Transmission and detection of prions in feces.
The Journal of infectious diseases 2008;198(1):81-9.
2008: Feng Brian Y; Toyama Brandon H; Wille Holger; Colby David W; Collins Sean R; May Barnaby C H; Prusiner Stanley B; Weissman Jonathan; Shoichet Brian K
Small-molecule aggregates inhibit amyloid polymerization.
Nature chemical biology 2008;4(3):197-9.
2008: Stöhr Jan; Weinmann Nicole; Wille Holger; Kaimann Tina; Nagel-Steger Luitgard; Birkmann Eva; Panza Giannantonio; Prusiner Stanley B; Eigen Manfred; Riesner Detlev
Mechanisms of prion protein assembly into amyloid.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2409-14.
2007: Colby David W; Zhang Qiang; Wang Shuyi; Groth Darlene; Legname Giuseppe; Riesner Detlev; Prusiner Stanley B
Prion detection by an amyloid seeding assay.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20914-9.
2007: Müller Henrik; Stitz Lothar; Wille Holger; Prusiner Stanley B; Riesner Detlev
Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation.
The Journal of biological chemistry 2007;282(49):35855-67.
2007: Ghaemmaghami Sina; Phuan Puay-Wah; Perkins Beth; Ullman Julie; May Barnaby C H; Cohen Fred E; Prusiner Stanley B
Cell division modulates prion accumulation in cultured cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(46):17971-6.
2007: Wille Holger; Govaerts Cédric; Borovinskiy Alexander; Latawiec Diane; Downing Kenneth H; Cohen Fred E; Prusiner Stanley B
Electron crystallography of the scrapie prion protein complexed with heavy metals.
Archives of biochemistry and biophysics 2007;467(2):239-48.
2007: King David J; Safar Jiri G; Legname Giuseppe; Prusiner Stanley B
Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites.
Journal of molecular biology 2007;369(4):1001-14.
2007: Norrby Erling; Prusiner Stanley B
Polio and Nobel prizes: looking back 50 years.
Annals of neurology 2007;61(5):385-95.
2007: Diez Margarita; Groth Darlene; DeArmond Stephen J; Prusiner Stanley B; Hökfelt Tomas
Changes in neuropeptide expression in mice infected with prions.
Neurobiology of aging 2007;28(5):748-65.
2007: Phuan Puay-Wah; Zorn Julie A; Safar Jiri; Giles Kurt; Prusiner Stanley B; Cohen Fred E; May Barnaby C H
Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds.
The Journal of general virology 2007;88(Pt 4):1392-401.
2007: Karpuj Marcela V; Giles Kurt; Gelibter-Niv Sagit; Scott Michael R; Lingappa Vishwanath R; Szoka Francis C; Peretz David; Denetclaw Wilfred; Prusiner Stanley B
Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells.
Molecular medicine (Cambridge, Mass.) 2007;13(3-4):190-8.
2007: Philipp Wolfgang J; Groth Darlene; Giles Kurt; Vodrazka Pavel; Schimmel Heinz; Feyssaguet Muriel; Toomik Reet; Schacher Pascal; Osman Awad A; Lachmann Ingolf; Wear Angus; Arsac Jean-Noel; Prusiner Stanley B
Transgenic mouse brains for the evaluation and quality control of BSE tests.
Biological chemistry 2007;388(3):349-54.
2007: Tremblay Patrick; Bouzamondo-Bernstein Essia; Heinrich Cornelia; Prusiner Stanley B; DeArmond Stephen J
Developmental expression of PrP in the post-implantation embryo.
Brain research 2007;1139():60-7.
2007: May Barnaby C H; Zorn Julie A; Witkop Juanita; Sherrill John; Wallace Andrew C; Legname Giuseppe; Prusiner Stanley B; Cohen Fred E
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.
Journal of medicinal chemistry 2007;50(1):65-73.
2006: Legname Giuseppe; Nguyen Hoang-Oanh B; Peretz David; Cohen Fred E; DeArmond Stephen J; Prusiner Stanley B
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19105-10.
2006: Boy Jana; Leergaard Trygve B; Schmidt Thorsten; Odeh Francis; Bichelmeier Ulrike; Nuber Silke; Holzmann Carsten; Wree Andreas; Prusiner Stanley B; Bujard Hermann; Riess Olaf; Bjaalie Jan G
Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.
NeuroImage 2006;33(2):449-62.
2006: Leclerc E; Serban H; Prusiner S B; Burton D R; Williamson R A
Copper induces conformational changes in the N-terminal part of cell-surface PrPC.
Archives of virology 2006;151(11):2103-9.
2006: Luginbühl Béatrice; Kanyo Zoltan; Jones R Mark; Fletterick Robert J; Prusiner Stanley B; Cohen Fred E; Williamson R Anthony; Burton Dennis R; Plückthun Andreas
Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation.
Journal of molecular biology 2006;363(1):75-97.
2006: Tamgüney Gültekin; Giles Kurt; Bouzamondo-Bernstein Essia; Bosque Patrick J; Miller Michael W; Safar Jiri; DeArmond Stephen J; Prusiner Stanley B
Transmission of elk and deer prions to transgenic mice.
Journal of virology 2006;80(18):9104-14.
2006: May Barnaby C H; Witkop Juanita; Sherrill John; Anderson Marc O; Madrid Peter B; Zorn Julie A; Prusiner Stanley B; Cohen Fred E; Guy R Kiplin
Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells.
Bioorganic & medicinal chemistry letters 2006;16(18):4913-6.
2006: Safar Jiri G; Wille Holger; Geschwind Michael D; Deering Camille; Latawiec Diane; Serban Ana; King David J; Legname Giuseppe; Weisgraber Karl H; Mahley Robert W; Miller Bruce L; Dearmond Stephen J; Prusiner Stanley B
Human prions and plasma lipoproteins.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(30):11312-7.
2006: Huang Yong; Okochi Hideaki; May Barnaby C H; Legname Giuseppe; Prusiner Stanley B; Benet Leslie Z; Guglielmo B Joseph; Lin Emil T
Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(7):1136-44.
2006: Giri Ranjit K; Young Rebecca; Pitstick Rose; DeArmond Stephen J; Prusiner Stanley B; Carlson George A
Prion infection of mouse neurospheres.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3875-80.
2006: Lim Kwang Hun; Nguyen Tuan N; Damo Steven M; Mazur Tanya; Ball Haydn L; Prusiner Stanley B; Pines Alexander; Wemmer David E
Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L).
Solid state nuclear magnetic resonance 2006;29(1-3):183-90.
2006: Peretz David; Supattapone Surachai; Giles Kurt; Vergara Julie; Freyman Yevgeniy; Lessard Pierre; Safar Jiri G; Glidden David V; McCulloch Charles; Nguyen Hoang-Oanh B; Scott Michael; Dearmond Stephen J; Prusiner Stanley B
Inactivation of prions by acidic sodium dodecyl sulfate.
Journal of virology 2006;80(1):322-31.
2006: Prusiner Stanley B; McCarty Maclyn
Discovering DNA encodes heredity and prions are infectious proteins.
Annual review of genetics 2006;40():25-45.
2005: Kanaani Jamil; Prusiner Stanley B; Diacovo Julia; Baekkeskov Steinunn; Legname Giuseppe
Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro.
Journal of neurochemistry 2005;95(5):1373-86.
2005: Lee In Su; Long Jeffrey R; Prusiner Stanley B; Safar Jiri G
Selective precipitation of prions by polyoxometalate complexes.
Journal of the American Chemical Society 2005;127(40):13802-3.
2005: Safar Jiri G; DeArmond Stephen J; Kociuba Katarzyna; Deering Camille; Didorenko Svetlana; Bouzamondo-Bernstein Essia; Prusiner Stanley B; Tremblay Patrick
Prion clearance in bigenic mice.
The Journal of general virology 2005;86(Pt 10):2913-23.
2005: Safar Jiri G; Kellings Klaus; Serban Ana; Groth Darlene; Cleaver James E; Prusiner Stanley B; Riesner Detlev
Search for a prion-specific nucleic acid.
Journal of virology 2005;79(16):10796-806.
2005: Leffers Karl-Werner; Wille Holger; Stöhr Jan; Junger Erika; Prusiner Stanley B; Riesner Detlev
Assembly of natural and recombinant prion protein into fibrils.
Biological chemistry 2005;386(6):569-80.
2005: Scott Michael R; Peretz David; Nguyen Hoang-Oanh B; Dearmond Stephen J; Prusiner Stanley B
Transmission barriers for bovine, ovine, and human prions in transgenic mice.
Journal of virology 2005;79(9):5259-71.
2005: Safar Jiri G; Geschwind Michael D; Deering Camille; Didorenko Svetlana; Sattavat Mamta; Sanchez Henry; Serban Ana; Vey Martin; Baron Henry; Giles Kurt; Miller Bruce L; Dearmond Stephen J; Prusiner Stanley B
Diagnosis of human prion disease.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3501-6.
2005: Legname Giuseppe; Nguyen Hoang-Oanh B; Baskakov Ilia V; Cohen Fred E; Dearmond Stephen J; Prusiner Stanley B
Strain-specified characteristics of mouse synthetic prions.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2168-73.
2005: Ishikura Nako; Clever Jared L; Bouzamondo-Bernstein Essia; Samayoa Erik; Prusiner Stanley B; Huang Eric J; DeArmond Stephen J
Notch-1 activation and dendritic atrophy in prion disease.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):886-91.
2004: Requena Jesús R; Dimitrova Mariana N; Legname Giuseppe; Teijeira Susana; Prusiner Stanley B; Levine Rodney L
Oxidation of methionine residues in the prion protein by hydrogen peroxide.
Archives of biochemistry and biophysics 2004;432(2):188-95.
2004: Yung Lotus; Huang Yong; Lessard Pierre; Legname Giuseppe; Lin Emil T; Baldwin Michael; Prusiner Stanley B; Ryou Chongsuk; Guglielmo B Joseph
Pharmacokinetics of quinacrine in the treatment of prion disease.
BMC infectious diseases 2004;4():53.
2004: Serban Ana; Legname Giuseppe; Hansen Kirk; Kovaleva Nadia; Prusiner Stanley B
Immunoglobulins in urine of hamsters with scrapie.
The Journal of biological chemistry 2004;279(47):48817-20.
2004: Bouzamondo-Bernstein Essia; Hopkins Stephanie D; Spilman Patricia; Uyehara-Lock Jane; Deering Camille; Safar Jiri; Prusiner Stanley B; Ralston Henry J; DeArmond Stephen J
The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system.
Journal of neuropathology and experimental neurology 2004;63(8):882-99.
2004: Legname Giuseppe; Baskakov Ilia V; Nguyen Hoang-Oanh B; Riesner Detlev; Cohen Fred E; DeArmond Stephen J; Prusiner Stanley B
Synthetic mammalian prions.
Science (New York, N.Y.) 2004;305(5684):673-6.
2004: Prusiner Stanley B
Detecting mad cow disease.
Scientific American 2004;291(1):86-93.
2004: Govaerts Cédric; Wille Holger; Prusiner Stanley B; Cohen Fred E
Evidence for assembly of prions with left-handed beta-helices into trimers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(22):8342-7.
2004: Schmitt-Ulms Gerold; Hansen Kirk; Liu Jialing; Cowdrey Cynthia; Yang Jian; DeArmond Stephen J; Cohen Fred E; Prusiner Stanley B; Baldwin Michael A
Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.
Nature biotechnology 2004;22(6):724-31.
2004: May Barnaby C H; Govaerts Cedric; Prusiner Stanley B; Cohen Fred E
Prions: so many fibers, so little infectivity.
Trends in biochemical sciences 2004;29(4):162-5.
2004: Baskakov Ilia V; Legname Giuseppe; Gryczynski Zygmunt; Prusiner Stanley B
The peculiar nature of unfolding of the human prion protein.
Protein science : a publication of the Protein Society 2004;13(3):586-95.
2004: Goldman Jill S; Miller Bruce L; Safar Jiri; de Tourreil Sunita; Martindale Jennifer L; Prusiner Stanley B; Geschwind Michael D
When sporadic disease is not sporadic: the potential for genetic etiology.
Archives of neurology 2004;61(2):213-6.
2004: Tremblay Patrick; Ball Haydn L; Kaneko Kiyotoshi; Groth Darlene; Hegde Ramanujan S; Cohen Fred E; DeArmond Stephen J; Prusiner Stanley B; Safar Jiri G
Mutant PrPSc conformers induced by a synthetic peptide and several prion strains.
Journal of virology 2004;78(4):2088-99.
2004: Prusiner Stanley B
Early evidence that a protease-resistant protein is an active component of the infectious prion.
Cell 2004;116(2 Suppl):S109, 1 p following S113.
2003: Peters Peter J; Mironov Alexander; Peretz David; van Donselaar Elly; Leclerc Estelle; Erpel Susanne; DeArmond Stephen J; Burton Dennis R; Williamson R Anthony; Vey Martin; Prusiner Stanley B
Trafficking of prion proteins through a caveolae-mediated endosomal pathway.
The Journal of cell biology 2003;162(4):703-17.
2003: Mironov Alexander; Latawiec Diane; Wille Holger; Bouzamondo-Bernstein Essia; Legname Giuseppe; Williamson R Anthony; Burton Dennis; DeArmond Stephen J; Prusiner Stanley B; Peters Peter J
Cytosolic prion protein in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(18):7183-93.
2003: Ryou Chongsuk; Legname Giuseppe; Peretz David; Craig John C; Baldwin Michael A; Prusiner Stanley B
Differential inhibition of prion propagation by enantiomers of quinacrine.
Laboratory investigation; a journal of technical methods and pathology 2003;83(6):837-43.
2003: Burns Colin S; Aronoff-Spencer Eliah; Legname Giuseppe; Prusiner Stanley B; Antholine William E; Gerfen Gary J; Peisach Jack; Millhauser Glenn L
Copper coordination in the full-length, recombinant prion protein.
Biochemistry 2003;42(22):6794-803.
2003: Ryou Chongsuk; Prusiner Stanley B; Legname Giuseppe
Cooperative binding of dominant-negative prion protein to kringle domains.
Journal of molecular biology 2003;329(2):323-33.
2003: Korth Carsten; Kaneko Kiyotoshi; Groth Darlene; Heye Norbert; Telling Glenn; Mastrianni James; Parchi Piero; Gambetti Pierluigi; Will Robert; Ironside James; Heinrich Cornelia; Tremblay Patrick; DeArmond Stephen J; Prusiner Stanley B
Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4784-9.
2003: DeArmond Stephen J; Prusiner Stanley B
Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment.
Clinics in laboratory medicine 2003;23(1):1-41.
2003: May Barnaby C H; Fafarman Aaron T; Hong Septima B; Rogers Michael; Deady Leslie W; Prusiner Stanley B; Cohen Fred E
Potent inhibition of scrapie prion replication in cultured cells by bis-acridines.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3416-21.
2003: Qin Kefeng; Coomaraswamy Janaky; Mastrangelo Peter; Yang Ying; Lugowski Stan; Petromilli Chris; Prusiner Stanley B; Fraser Paul E; Goldberg Jonathan M; Chakrabartty Avijit; Westaway David
The PrP-like protein Doppel binds copper.
The Journal of biological chemistry 2003;278(11):8888-96.
2003: Leclerc Estelle; Peretz David; Ball Haydn; Solforosi Laura; Legname Giuseppe; Safar Jiri; Serban Ana; Prusiner Stanley B; Burton Dennis R; Williamson R Anthony
Conformation of PrP(C) on the cell surface as probed by antibodies.
Journal of molecular biology 2003;326(2):475-83.
2002: Legname Giuseppe; Nelken Peter; Guan Zhengyu; Kanyo Zoltan F; DeArmond Stephen J; Prusiner Stanley B
Prion and doppel proteins bind to granule cells of the cerebellum.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16285-90.
2002: Prusiner Stanley B
Historical essay. Discovering the cause of AIDS.
Science (New York, N.Y.) 2002;298(5599):1726.
2002: Safar Jiri G; Scott Michael; Monaghan Jeff; Deering Camille; Didorenko Svetlana; Vergara Julie; Ball Haydn; Legname Giuseppe; Leclerc Estelle; Solforosi Laura; Serban Hana; Groth Darlene; Burton Dennis R; Prusiner Stanley B; Williamson R Anthony
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice.
Nature biotechnology 2002;20(11):1147-50.
2002: Kuwata Kazuo; Li Hua; Yamada Hiroaki; Legname Giuseppe; Prusiner Stanley B; Akasaka Kazuyuki; James Thomas L
Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?
Biochemistry 2002;41(41):12277-83.
2002: Perrier Véronique; Kaneko Kiyotoshi; Safar Jiri; Vergara Julie; Tremblay Patrick; DeArmond Stephen J; Cohen Fred E; Prusiner Stanley B; Wallace Andrew C
Dominant-negative inhibition of prion replication in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):13079-84.
2002: Peretz David; Williamson R Anthony; Legname Giuseppe; Matsunaga Yoichi; Vergara Julie; Burton Dennis R; DeArmond Stephen J; Prusiner Stanley B; Scott Michael R
A change in the conformation of prions accompanies the emergence of a new prion strain.
Neuron 2002;34(6):921-32.
2002: Baskakov Ilia V; Legname Giuseppe; Baldwin Michael A; Prusiner Stanley B; Cohen Fred E
Pathway complexity of prion protein assembly into amyloid.
The Journal of biological chemistry 2002;277(24):21140-8.
2002: Bosque Patrick J; Ryou Chongsuk; Telling Glenn; Peretz David; Legname Giuseppe; DeArmond Stephen J; Prusiner Stanley B
Prions in skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3812-7.
2002: Wille Holger; Michelitsch Melissa D; Guenebaut Vincent; Supattapone Surachai; Serban Ana; Cohen Fred E; Agard David A; Prusiner Stanley B
Structural studies of the scrapie prion protein by electron crystallography.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3563-8.
2002: Nicholson Eric M; Mo Huaping; Prusiner Stanley B; Cohen Fred E; Marqusee Susan
Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation.
Journal of molecular biology 2002;316(3):807-15.
2001: Mastrianni J A; Capellari S; Telling G C; Han D; Bosque P; Prusiner S B; DeArmond S J
Inherited prion disease caused by the V210I mutation: transmission to transgenic mice.
Neurology 2001;57(12):2198-205.
2001: Schmitt-Ulms G; Legname G; Baldwin M A; Ball H L; Bradon N; Bosque P J; Crossin K L; Edelman G M; DeArmond S J; Cohen F E; Prusiner S B
Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein.
Journal of molecular biology 2001;314(5):1209-25.
2001: Moore R C; Mastrangelo P; Bouzamondo E; Heinrich C; Legname G; Prusiner S B; Hood L; Westaway D; DeArmond S J; Tremblay P
Doppel-induced cerebellar degeneration in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15288-93.
2001: Moore R C; Xiang F; Monaghan J; Han D; Zhang Z; Edström L; Anvret M; Prusiner S B
Huntington disease phenocopy is a familial prion disease.
American journal of human genetics 2001;69(6):1385-8.
2001: Ball H L; King D S; Cohen F E; Prusiner S B; Baldwin M A
Engineering the prion protein using chemical synthesis.
The journal of peptide research : official journal of the American Peptide Society 2001;58(5):357-74.
2001: Schlumpberger M; Prusiner S B; Herskowitz I
Induction of distinct [URE3] yeast prion strains.
Molecular and cellular biology 2001;21(20):7035-46.
2001: Laws D D; Bitter H M; Liu K; Ball H L; Kaneko K; Wille H; Cohen F E; Prusiner S B; Pines A; Wemmer D E
Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11686-90.
2001: Peretz D; Williamson R A; Kaneko K; Vergara J; Leclerc E; Schmitt-Ulms G; Mehlhorn I R; Legname G; Wormald M R; Rudd P M; Dwek R A; Burton D R; Prusiner S B
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.
Nature 2001;412(6848):739-43.
2001: Korth C; May B C; Cohen F E; Prusiner S B
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9836-41.
2001: Diez M; DeArmond S J; Groth D; Prusiner S B; Hökfelt T
Decreased MK-801 binding in discrete hippocampal regions of prion-infected mice.
Neurobiology of disease 2001;8(4):692-9.
2001: Matsunaga Y; Peretz D; Williamson A; Burton D; Mehlhorn I; Groth D; Cohen F E; Prusiner S B; Baldwin M A
Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH.
Proteins 2001;44(2):110-8.
2001: Requena J R; Groth D; Legname G; Stadtman E R; Prusiner S B; Levine R L
Copper-catalyzed oxidation of the recombinant SHa(29-231) prion protein.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7170-5.
2001: Baskakov I V; Legname G; Prusiner S B; Cohen F E
Folding of prion protein to its native alpha-helical conformation is under kinetic control.
The Journal of biological chemistry 2001;276(23):19687-90.
2001: Prusiner S B
Shattuck lecture--neurodegenerative diseases and prions.
The New England journal of medicine 2001;344(20):1516-26.
2001: Jansen K; Schäfer O; Birkmann E; Post K; Serban H; Prusiner S B; Riesner D
Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form.
Biological chemistry 2001;382(4):683-91.
2001: Rudd P M; Wormald M R; Wing D R; Prusiner S B; Dwek R A
Prion glycoprotein: structure, dynamics, and roles for the sugars.
Biochemistry 2001;40(13):3759-66.
2001: Leclerc E; Peretz D; Ball H; Sakurai H; Legname G; Serban A; Prusiner S B; Burton D R; Williamson R A
Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form.
The EMBO journal 2001;20(7):1547-54.
2001: Peretz D; Scott M R; Groth D; Williamson R A; Burton D R; Cohen F E; Prusiner S B
Strain-specified relative conformational stability of the scrapie prion protein.
Protein science : a publication of the Protein Society 2001;10(4):854-63.
2001: Harrison P M; Chan H S; Prusiner S B; Cohen F E
Conformational propagation with prion-like characteristics in a simple model of protein folding.
Protein science : a publication of the Protein Society 2001;10(4):819-35.
2001: Supattapone S; Bouzamondo E; Ball H L; Wille H; Nguyen H O; Cohen F E; DeArmond S J; Prusiner S B; Scott M
A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice.
Molecular and cellular biology 2001;21(7):2608-16.
2001: Supattapone S; Wille H; Uyechi L; Safar J; Tremblay P; Szoka F C; Cohen F E; Prusiner S B; Scott M R
Branched polyamines cure prion-infected neuroblastoma cells.
Journal of virology 2001;75(7):3453-61.
2001: Viles J H; Donne D; Kroon G; Prusiner S B; Cohen F E; Dyson H J; Wright P E
Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics.
Biochemistry 2001;40(9):2743-53.
2001: Mo H; Moore R C; Cohen F E; Westaway D; Prusiner S B; Wright P E; Dyson H J
Two different neurodegenerative diseases caused by proteins with similar structures.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2352-7.
2001: Supattapone S; Muramoto T; Legname G; Mehlhorn I; Cohen F E; DeArmond S J; Prusiner S B; Scott M R
Identification of two prion protein regions that modify scrapie incubation time.
Journal of virology 2001;75(3):1408-13.
2000: Supattapone S; Nguyen H O; Muramoto T; Cohen F E; DeArmond S J; Prusiner S B; Scott M
Affinity-tagged miniprion derivatives spontaneously adopt protease-resistant conformations.
Journal of virology 2000;74(24):11928-34.
2000: Aronoff-Spencer E; Burns C S; Avdievich N I; Gerfen G J; Peisach J; Antholine W E; Ball H L; Cohen F E; Prusiner S B; Millhauser G L
Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy.
Biochemistry 2000;39(45):13760-71.
2000: Stephenson D A; Chiotti K; Ebeling C; Groth D; DeArmond S J; Prusiner S B; Carlson G A
Quantitative trait loci affecting prion incubation time in mice.
Genomics 2000;69(1):47-53.
2000: Korth C; Kaneko K; Prusiner S B
Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains.
The Journal of general virology 2000;81(Pt 10):2555-63.
2000: Silverman G L; Qin K; Moore R C; Yang Y; Mastrangelo P; Tremblay P; Prusiner S B; Cohen F E; Westaway D
Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.
The Journal of biological chemistry 2000;275(35):26834-41.
2000: Bouzamondo E; Milroy A M; Ralston H J; Prusiner S B; DeArmond S J
Selective neuronal vulnerability during experimental scrapie infection: insights from an ultrastructural investigation.
Brain research 2000;874(2):210-5.
2000: Inouye H; Bond J; Baldwin M A; Ball H L; Prusiner S B; Kirschner D A
Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions.
Journal of molecular biology 2000;300(5):1283-96.
2000: Wille H; Prusiner S B; Cohen F E
Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein.
Journal of structural biology 2000;130(2-3):323-38.
2000: Perrier V; Wallace A C; Kaneko K; Safar J; Prusiner S B; Cohen F E
Mimicking dominant negative inhibition of prion replication through structure-based drug design.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6073-8.
2000: Bosque P J; Prusiner S B
Cultured cell sublines highly susceptible to prion infection.
Journal of virology 2000;74(9):4377-86.
2000: Zulianello L; Kaneko K; Scott M; Erpel S; Han D; Cohen F E; Prusiner S B
Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein.
Journal of virology 2000;74(9):4351-60.
2000: Schlumpberger M; Wille H; Baldwin M A; Butler D A; Herskowitz I; Prusiner S B
The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein.
Protein science : a publication of the Protein Society 2000;9(3):440-51.
2000: Baskakov I V; Aagaard C; Mehlhorn I; Wille H; Groth D; Baldwin M A; Prusiner S B; Cohen F E
Self-assembly of recombinant prion protein of 106 residues.
Biochemistry 2000;39(10):2792-804.
2000: Whittal R M; Ball H L; Cohen F E; Burlingame A L; Prusiner S B; Baldwin M A
Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry.
Protein science : a publication of the Protein Society 2000;9(2):332-43.
2000: Kaneko K; Ball H L; Wille H; Zhang H; Groth D; Torchia M; Tremblay P; Safar J; Prusiner S B; DeArmond S J; Baldwin M A; Cohen F E
A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice.
Journal of molecular biology 2000;295(4):997-1007.
2000: Safar J; Cohen F E; Prusiner S B
Quantitative traits of prion strains are enciphered in the conformation of the prion protein.
Archives of virology. Supplementum 2000;(16):227-35.
2000: Scott M R; Supattapone S; Nguyen H O; DeArmond S J; Prusiner S B
Transgenic models of prion disease.
Archives of virology. Supplementum 2000;(16):113-24.
1999: Hegde R S; Tremblay P; Groth D; DeArmond S J; Prusiner S B; Lingappa V R
Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
Nature 1999;402(6763):822-6.
1999: Scott M R; Will R; Ironside J; Nguyen H O; Tremblay P; DeArmond S J; Prusiner S B
Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15137-42.
1999: Tatzelt J; Groth D F; Torchia M; Prusiner S B; DeArmond S J
Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie.
Journal of neuropathology and experimental neurology 1999;58(12):1244-9.
1999: Supattapone S; Nguyen H O; Cohen F E; Prusiner S B; Scott M R
Elimination of prions by branched polyamines and implications for therapeutics.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14529-34.
1999: Rudd P M; Endo T; Colominas C; Groth D; Wheeler S F; Harvey D J; Wormald M R; Serban H; Prusiner S B; Kobata A; Dwek R A
Glycosylation differences between the normal and pathogenic prion protein isoforms.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13044-9.
1999: Kanyo Z F; Pan K M; Williamson R A; Burton D R; Prusiner S B; Fletterick R J; Cohen F E
Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
Journal of molecular biology 1999;293(4):855-63.
1999: Moore R C; Lee I Y; Silverman G L; Harrison P M; Strome R; Heinrich C; Karunaratne A; Pasternak S H; Chishti M A; Liang Y; Mastrangelo P; Wang K; Smit A F; Katamine S; Carlson G A; Cohen F E; Prusiner S B; Melton D W; Tremblay P; Hood L E; Westaway D
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
Journal of molecular biology 1999;292(4):797-817.
1999: Nishida N; Tremblay P; Sugimoto T; Shigematsu K; Shirabe S; Petromilli C; Erpel S P; Nakaoke R; Atarashi R; Houtani T; Torchia M; Sakaguchi S; DeArmond S J; Prusiner S B; Katamine S
A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.
Laboratory investigation; a journal of technical methods and pathology 1999;79(6):689-97.
1999: Mastrianni J A; Nixon R; Layzer R; Telling G C; Han D; DeArmond S J; Prusiner S B
Prion protein conformation in a patient with sporadic fatal insomnia.
The New England journal of medicine 1999;340(21):1630-8.
1999: Liu H; Farr-Jones S; Ulyanov N B; Llinas M; Marqusee S; Groth D; Cohen F E; Prusiner S B; James T L
Solution structure of Syrian hamster prion protein rPrP(90-231).
Biochemistry 1999;38(17):5362-77.
1999: Supattapone S; Bosque P; Muramoto T; Wille H; Aagaard C; Peretz D; Nguyen H O; Heinrich C; Torchia M; Safar J; Cohen F E; DeArmond S J; Prusiner S B; Scott M
Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice.
Cell 1999;96(6):869-78.
1999: Viles J H; Cohen F E; Prusiner S B; Goodin D B; Wright P E; Dyson H J
Copper binding to the prion protein: structural implications of four identical cooperative binding sites.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2042-7.
1999: Harrison P M; Chan H S; Prusiner S B; Cohen F E
Thermodynamics of model prions and its implications for the problem of prion protein folding.
Journal of molecular biology 1999;286(2):593-606.
1999: Wille H; Prusiner S B
Ultrastructural studies on scrapie prion protein crystals obtained from reverse micellar solutions.
Biophysical journal 1999;76(2):1048-62.
1998: Post K; Pitschke M; Schäfer O; Wille H; Appel T R; Kirsch D; Mehlhorn I; Serban H; Prusiner S B; Riesner D
Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation.
Biological chemistry 1998;379(11):1307-17.
1998: Prusiner S B
Prions.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13363-83.
1998: Williamson R A; Peretz D; Pinilla C; Ball H; Bastidas R B; Rozenshteyn R; Houghten R A; Prusiner S B; Burton D R
Mapping the prion protein using recombinant antibodies.
Journal of virology 1998;72(11):9413-8.
1998: Lee I Y; Westaway D; Smit A F; Wang K; Seto J; Chen L; Acharya C; Ankener M; Baskin D; Cooper C; Yao H; Prusiner S B; Hood L E
Complete genomic sequence and analysis of the prion protein gene region from three mammalian species.
Genome research 1998;8(10):1022-37.
1998: Safar J; Wille H; Itri V; Groth D; Serban H; Torchia M; Cohen F E; Prusiner S B
Eight prion strains have PrP(Sc) molecules with different conformations.
Nature medicine 1998;4(10):1157-65.
1998: Tremblay P; Meiner Z; Galou M; Heinrich C; Petromilli C; Lisse T; Cayetano J; Torchia M; Mobley W; Bujard H; DeArmond S J; Prusiner S B
Doxycycline control of prion protein transgene expression modulates prion disease in mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12580-5.
1998: Baldwin M A; James T L; Cohen F E; Prusiner S B
The three-dimensional structure of prion protein: implications for prion disease.
Biochemical Society transactions 1998;26(3):481-6.
1998: Prusiner S B
The prion diseases.
Brain pathology (Zurich, Switzerland) 1998;8(3):499-513.
1998: Hökfelt T; Broberger C; Zhang X; Diez M; Kopp J; Xu Z; Landry M; Bao L; Schalling M; Koistinaho J; DeArmond S J; Prusiner S; Gong J; Walsh J H
Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system.
Brain research. Brain research reviews 1998;26(2-3):154-66.
1998: Prusiner S B; Scott M R; DeArmond S J; Cohen F E
Prion protein biology.
Cell 1998;93(3):337-48.
1998: Stöckel J; Safar J; Wallace A C; Cohen F E; Prusiner S B
Prion protein selectively binds copper(II) ions.
Biochemistry 1998;37(20):7185-93.
1998: Hegde R S; Mastrianni J A; Scott M R; DeFea K A; Tremblay P; Torchia M; DeArmond S J; Prusiner S B; Lingappa V R
A transmembrane form of the prion protein in neurodegenerative disease.
Science (New York, N.Y.) 1998;279(5352):827-34.
1998: DeArmond S J; Mobley W C; DeMott D L; Barry R A; Beckstead J H; Prusiner S B
Changes in the localization of brain prion proteins during scrapie infection.
Neurology 1998;50(1):1271-80; discussion 2.
1998: Safar J; Prusiner S B
Molecular studies of prion diseases.
Progress in brain research 1998;117():421-34.
1998: Cohen F E; Prusiner S B
Pathologic conformations of prion proteins.
Annual review of biochemistry 1998;67():793-819.
1997: Blochberger T C; Cooper C; Peretz D; Tatzelt J; Griffith O H; Baldwin M A; Prusiner S B
Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system.
Protein engineering 1997;10(12):1465-73.
1997: DeArmond S J; Sánchez H; Yehiely F; Qiu Y; Ninchak-Casey A; Daggett V; Camerino A P; Cayetano J; Rogers M; Groth D; Torchia M; Tremblay P; Scott M R; Cohen F E; Prusiner S B
Selective neuronal targeting in prion disease.
Neuron 1997;19(6):1337-48.
1997: Scott M R; Safar J; Telling G; Nguyen O; Groth D; Torchia M; Koehler R; Tremblay P; Walther D; Cohen F E; DeArmond S J; Prusiner S B
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14279-84.
1997: Donne D G; Viles J H; Groth D; Mehlhorn I; James T L; Cohen F E; Prusiner S B; Wright P E; Dyson H J
Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13452-7.
1997: Scott M R; Groth D; Tatzelt J; Torchia M; Tremblay P; DeArmond S J; Prusiner S B
Propagation of prion strains through specific conformers of the prion protein.
Journal of virology 1997;71(12):9032-44.
1997: Diez M; Koistinaho J; Dearmond S J; Groth D; Prusiner S B; Hökfelt T
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):13267-72.
1997: Schätzl H M; Laszlo L; Holtzman D M; Tatzelt J; DeArmond S J; Weiner R I; Mobley W C; Prusiner S B
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.
Journal of virology 1997;71(11):8821-31.
1997: Peretz D; Williamson R A; Matsunaga Y; Serban H; Pinilla C; Bastidas R B; Rozenshteyn R; James T L; Houghten R A; Cohen F E; Prusiner S B; Burton D R
A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform.
Journal of molecular biology 1997;273(3):614-22.
1997: Prusiner S B
Prion diseases and the BSE crisis.
Science (New York, N.Y.) 1997;278(5336):245-51.
1997: James T L; Liu H; Ulyanov N B; Farr-Jones S; Zhang H; Donne D G; Kaneko K; Groth D; Mehlhorn I; Prusiner S B; Cohen F E
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10086-91.
1997: Kaneko K; Zulianello L; Scott M; Cooper C M; Wallace A C; James T L; Cohen F E; Prusiner S B
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10069-74.
1997: Meiner Z; Gabizon R; Prusiner S B
Familial Creutzfeldt-Jakob disease. Codon 200 prion disease in Libyan Jews.
Medicine 1997;76(4):227-37.
1997: Kaneko K; Wille H; Mehlhorn I; Zhang H; Ball H; Cohen F E; Baldwin M A; Prusiner S B
Molecular properties of complexes formed between the prion protein and synthetic peptides.
Journal of molecular biology 1997;270(4):574-86.
1997: Muramoto T; DeArmond S J; Scott M; Telling G C; Cohen F E; Prusiner S B
Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix.
Nature medicine 1997;3(7):750-5.
1997: Lundberg K M; Stenland C J; Cohen F E; Prusiner S B; Millhauser G L
Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR.
Chemistry & biology 1997;4(5):345-55.
1997: Telling G C; Tremblay P; Torchia M; Dearmond S J; Cohen F E; Prusiner S B
N-terminally tagged prion protein supports prion propagation in transgenic mice.
Protein science : a publication of the Protein Society 1997;6(4):825-33.
1997: Zhang H; Stockel J; Mehlhorn I; Groth D; Baldwin M A; Prusiner S B; James T L; Cohen F E
Physical studies of conformational plasticity in a recombinant prion protein.
Biochemistry 1997;36(12):3543-53.
1997: Kaneko K; Vey M; Scott M; Pilkuhn S; Cohen F E; Prusiner S B
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2333-8.
1997: Carlson G A; Banks S; Lund D; Reichert C; Groth D; Torchia M; Dearmond S J; Prusiner S B
Failure to transmit disease from gray tremor mutant mice.
Journal of virology 1997;71(3):2342-5.
1997: Harrison P M; Bamborough P; Daggett V; Prusiner S B; Cohen F E
The prion folding problem.
Current opinion in structural biology 1997;7(1):53-9.
1997: Schätzl H M; Da Costa M; Taylor L; Cohen F E; Prusiner S B
Prion protein gene variation among primates.
Journal of molecular biology 1997;265(2):257.
1997: Prusiner S B; Scott M R
Genetics of prions.
Annual review of genetics 1997;31():139-75.
1997: Yehiely F; Bamborough P; Da Costa M; Perry B J; Thinakaran G; Cohen F E; Carlson G A; Prusiner S B
Identification of candidate proteins binding to prion protein.
Neurobiology of disease 1997;3(4):339-55.
1996: Prusiner S B
Molecular biology and pathogenesis of prion diseases.
Trends in biochemical sciences 1996;21(12):482-7.
1996: Muramoto T; Scott M; Cohen F E; Prusiner S B
Recombinant scrapie-like prion protein of 106 amino acids is soluble.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15457-62.
1996: Tatzelt J; Prusiner S B; Welch W J
Chemical chaperones interfere with the formation of scrapie prion protein.
The EMBO journal 1996;15(23):6363-73.
1996: Vey M; Pilkuhn S; Wille H; Nixon R; DeArmond S J; Smart E J; Anderson R G; Taraboulos A; Prusiner S B
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14945-9.
1996: Telling G C; Parchi P; DeArmond S J; Cortelli P; Montagna P; Gabizon R; Mastrianni J; Lugaresi E; Gambetti P; Prusiner S B
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity.
Science (New York, N.Y.) 1996;274(5295):2079-82.
1996: Mastrianni J A; Iannicola C; Myers R M; DeArmond S; Prusiner S B
Mutation of the prion protein gene at codon 208 in familial Creutzfeldt-Jakob disease.
Neurology 1996;47(5):1305-12.
1996: Prusiner S B
Prion biology and diseases--laughing cannibals, mad cows, and scientific heresy.
Medicinal research reviews 1996;16(5):487-505.
1996: Wong K; Qiu Y; Hyun W; Nixon R; VanCleff J; Sanchez-Salazar J; Prusiner S B; DeArmond S J
Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release.
Neurology 1996;47(3):741-50.
1996: Diez M; Koistinaho J; DeArmond S J; Camerino A P; Groth D; Caytano J C; Prusiner S B; Hökfelt T
Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice.
Neuroreport 1996;7(12):1887-92.
1996: Heller J; Kolbert A C; Larsen R; Ernst M; Bekker T; Baldwin M; Prusiner S B; Pines A; Wemmer D E
Solid-state NMR studies of the prion protein H1 fragment.
Protein science : a publication of the Protein Society 1996;5(8):1655-61.
1996: Tatzelt J; Maeda N; Pekny M; Yang S L; Betsholtz C; Eliasson C; Cayetano J; Camerino A P; DeArmond S J; Prusiner S B
Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein.
Neurology 1996;47(2):449-53.
1996: Telling G C; Haga T; Torchia M; Tremblay P; DeArmond S J; Prusiner S B
Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.
Genes & development 1996;10(14):1736-50.
1996: Williamson R A; Peretz D; Smorodinsky N; Bastidas R; Serban H; Mehlhorn I; DeArmond S J; Prusiner S B; Burton D R
Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7279-82.
1996: Wille H; Zhang G F; Baldwin M A; Cohen F E; Prusiner S B
Separation of scrapie prion infectivity from PrP amyloid polymers.
Journal of molecular biology 1996;259(4):608-21.
1996: Mehlhorn I; Groth D; Stöckel J; Moffat B; Reilly D; Yansura D; Willett W S; Baldwin M; Fletterick R; Cohen F E; Vandlen R; Henner D; Prusiner S B
High-level expression and characterization of a purified 142-residue polypeptide of the prion protein.
Biochemistry 1996;35(17):5528-37.
1996: Lledo P M; Tremblay P; DeArmond S J; Prusiner S B; Nicoll R A
Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2403-7.
1996: Riesner D; Kellings K; Post K; Wille H; Serban H; Groth D; Baldwin M A; Prusiner S B
Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.
Journal of virology 1996;70(3):1714-22.
1996: Gabizon R; Telling G; Meiner Z; Halimi M; Kahana I; Prusiner S B
Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease.
Nature medicine 1996;2(1):59-64.
1996: Guan Z; Söderberg M; Sindelar P; Prusiner S B; Kristensson K; Dallner G
Lipid composition in scrapie-infected mouse brain: prion infection increases the levels of dolichyl phosphate and ubiquinone.
Journal of neurochemistry 1996;66(1):277-85.
1996: DeArmond S J; Qiu Y; Wong K; Nixon R; Hyun W; Prusiner S B; Mobley W C
Abnormal plasma membrane properties and functions in prion-infected cell lines.
Cold Spring Harbor symposia on quantitative biology 1996;61():531-40.
1996: Bamborough P; Wille H; Telling G C; Yehiely F; Prusiner S B; Cohen F E
Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations.
Cold Spring Harbor symposia on quantitative biology 1996;61():495-509.
1996: Prusiner S B
Molecular biology and genetics of prion diseases.
Cold Spring Harbor symposia on quantitative biology 1996;61():473-93.
1996: Huang Z; Prusiner S B; Cohen F E
Scrapie prions: a three-dimensional model of an infectious fragment.
Folding & design 1996;1(1):13-9.
1996: Wille H; Baldwin M A; Cohen F E; DeArmond S J; Prusiner S B
Prion protein amyloid: separation of scrapie infectivity from PrP polymers.
Ciba Foundation symposium 1996;199():181-99; discussion 199-201.
1996: Prusiner S B
Transgenetics of prion diseases.
Current topics in microbiology and immunology 1996;206():275-304.
1996: Scott M R; Telling G C; Prusiner S B
Transgenetics and gene targeting in studies of prion diseases.
Current topics in microbiology and immunology 1996;207():95-123.
1996: Huang Z; Prusiner S B; Cohen F E
Structures of prion proteins and conformational models for prion diseases.
Current topics in microbiology and immunology 1996;207():49-67.
1996: DeArmond S J; Prusiner S B
Transgenetics and neuropathology of prion diseases.
Current topics in microbiology and immunology 1996;207():125-46.
1996: Prusiner S B
Human prion diseases and neurodegeneration.
Current topics in microbiology and immunology 1996;207():1-17.
1995: Mastrianni J A; Curtis M T; Oberholtzer J C; Da Costa M M; DeArmond S; Prusiner S B; Garbern J Y
Prion disease (PrP-A117V) presenting with ataxia instead of dementia.
Neurology 1995;45(11):2042-50.
1995: Kaneko K; Peretz D; Pan K M; Blochberger T C; Wille H; Gabizon R; Griffith O H; Cohen F E; Baldwin M A; Prusiner S B
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11160-4.
1995: Wiese U; Wulfert M; Prusiner S B; Riesner D
Scanning for mutations in the human prion protein open reading frame by temporal temperature gradient gel electrophoresis.
Electrophoresis 1995;16(10):1851-60.
1995: Telling G C; Scott M; Mastrianni J; Gabizon R; Torchia M; Cohen F E; DeArmond S J; Prusiner S B
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein.
Cell 1995;83(1):79-90.
1995: Spudich S; Mastrianni J A; Wrensch M; Gabizon R; Meiner Z; Kahana I; Rosenmann H; Kahana E; Prusiner S B
Complete penetrance of Creutzfeldt-Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein gene.
Molecular medicine (Cambridge, Mass.) 1995;1(6):607-13.
1995: Nguyen J T; Inouye H; Baldwin M A; Fletterick R J; Cohen F E; Prusiner S B; Kirschner D A
X-ray diffraction of scrapie prion rods and PrP peptides.
Journal of molecular biology 1995;252(4):412-22.
1995: Baldwin M A; Cohen F E; Prusiner S B
Prion protein isoforms, a convergence of biological and structural investigations.
The Journal of biological chemistry 1995;270(33):19197-200.
1995: Zhang H; Kaneko K; Nguyen J T; Livshits T L; Baldwin M A; Cohen F E; James T L; Prusiner S B
Conformational transitions in peptides containing two putative alpha-helices of the prion protein.
Journal of molecular biology 1995;250(4):514-26.
1995: Prusiner S B
Molecular genetics and biophysics of prions.
Uirusu. Journal of virology 1995;45(1):5-42.
1995: Raeber A J; Muramoto T; Kornberg T B; Prusiner S B
Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster.
Mechanisms of development 1995;51(2-3):317-27.
1995: Kazmirski S L; Alonso D O; Cohen F E; Prusiner S B; Daggett V
Theoretical studies of sequence effects on the conformational properties of a fragment of the prion protein: implications for scrapie formation.
Chemistry & biology 1995;2(5):305-15.
1995: DeArmond S J; Prusiner S B
Etiology and pathogenesis of prion diseases.
The American journal of pathology 1995;146(4):785-811.
1995: Nguyen J; Baldwin M A; Cohen F E; Prusiner S B
Prion protein peptides induce alpha-helix to beta-sheet conformational transitions.
Biochemistry 1995;34(13):4186-92.
1995: Taraboulos A; Scott M; Semenov A; Avrahami D; Laszlo L; Prusiner S B;
Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform.
The Journal of cell biology 1995;129(1):121-32.
1995: Westaway D; Carlson G A; Prusiner S B
On safari with PrP: prion diseases of animals.
Trends in microbiology 1995;3(4):141-7.
1995: Tatzelt J; Zuo J; Voellmy R; Scott M; Hartl U; Prusiner S B; Welch W J
Scrapie prions selectively modify the stress response in neuroblastoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2944-8.
1995: Schätzl H M; Da Costa M; Taylor L; Cohen F E; Prusiner S B
Prion protein gene variation among primates.
Journal of molecular biology 1995;245(4):362-74.
1995: Prusiner S B
The prion diseases.
Scientific American 1995;272(1):48-51, 54-7.
1995: DeArmond S J; Prusiner S B
Prion protein transgenes and the neuropathology in prion diseases.
Brain pathology (Zurich, Switzerland) 1995;5(1):77-89.
1994: Jefferys J G; Empson R M; Whittington M A; Prusiner S B
Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones.
Neurobiology of disease 1994;1(1-2):25-30.
1994: Telling G C; Scott M; Hsiao K K; Foster D; Yang S L; Torchia M; Sidle K C; Collinge J; DeArmond S J; Prusiner S B
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9936-40.
1994: Prusiner S B
Neurodegeneration in humans caused by prions.
The Western journal of medicine 1994;161(3):264-72.
1994: Hsiao K K; Groth D; Scott M; Yang S L; Serban H; Rapp D; Foster D; Torchia M; Dearmond S J; Prusiner S B
Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9126-30.
1994: Huang Z; Gabriel J M; Baldwin M A; Fletterick R J; Prusiner S B; Cohen F E
Proposed three-dimensional structure for the cellular prion protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7139-43.
1994: Westaway D; Cooper C; Turner S; Da Costa M; Carlson G A; Prusiner S B
Structure and polymorphism of the mouse prion protein gene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6418-22.
1994: De Fea K A; Nakahara D H; Calayag M C; Yost C S; Mirels L F; Prusiner S B; Lingappa V R
Determinants of carboxyl-terminal domain translocation during prion protein biogenesis.
The Journal of biological chemistry 1994;269(24):16810-20.
1994: Carlson G A; Ebeling C; Yang S L; Telling G; Torchia M; Groth D; Westaway D; DeArmond S J; Prusiner S B
Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5690-4.
1994: Prusiner S B
Inherited prion diseases.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4611-4.
1994: Prusiner S B; Hsiao K K
Human prion diseases.
Annals of neurology 1994;35(4):385-95.
1994: Westaway D; Zuliani V; Cooper C M; Da Costa M; Neuman S; Jenny A L; Detwiler L; Prusiner S B
Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie.
Genes & development 1994;8(8):959-69.
1994: Cohen F E; Pan K M; Huang Z; Baldwin M; Fletterick R J; Prusiner S B
Structural clues to prion replication.
Science (New York, N.Y.) 1994;264(5158):530-1.
1994: Prusiner S B
Molecular biology and genetics of prion diseases.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994;343(1306):447-63.
1994: Kellings K; Prusiner S B; Riesner D
Nucleic acids in prion preparations: unspecific background or essential component?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994;343(1306):425-30.
1994: DeArmond S J; Yang S L; Cayetano-Canlas J; Groth D; Prusiner S B
The neuropathological phenotype in transgenic mice expressing different prion protein constructs.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994;343(1306):415-23.
1994: Gabizon R; Rosenman H; Meiner Z; Kahana I; Kahana E; Shugart Y; Ott J; Prusiner S B
Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994;343(1306):385-90.
1994: Carlson G A; DeArmond S J; Torchia M; Westaway D; Prusiner S B
Genetics of prion diseases and prion diversity in mice.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994;343(1306):363-9.
1994: Taraboulos A; Scott M; Semenov A; Avrahami D; Prusiner S B
Biosynthesis of the prion proteins in scrapie-infected cells in culture.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):303-7.
1994: Westaway D; DeArmond S J; Cayetano-Canlas J; Groth D; Foster D; Yang S L; Torchia M; Carlson G A; Prusiner S B
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins.
Cell 1994;76(1):117-29.
1994: Gomi H; Ikeda T; Kunieda T; Itohara S; Prusiner S B; Yamanouchi K
Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in zitter rats.
Neuroscience letters 1994;166(2):171-4.
1994: Prusiner S B; DeArmond S J
Prion diseases and neurodegeneration.
Annual review of neuroscience 1994;17():311-39.
1994: Fink J K; Peacock M L; Warren J T; Roses A D; Prusiner S B
Detecting prion protein gene mutations by denaturing gradient gel electrophoresis.
Human mutation 1994;4(1):42-50.
1994: Prusiner S B
Biology and genetics of prion diseases.
Annual review of microbiology 1994;48():655-86.
1994: Prusiner S B
A national strategy for development of effective methods for the prevention and treatment of Alzheimer's disease and related neurodegenerative disorders.
Neurobiology of aging 1994;15 Suppl 2():S29-32.
1993: Kristensson K; Feuerstein B; Taraboulos A; Hyun W C; Prusiner S B; DeArmond S J
Scrapie prions alter receptor-mediated calcium responses in cultured cells.
Neurology 1993;43(11):2335-41.
1993: Prusiner S B
Genetic and infectious prion diseases.
Archives of neurology 1993;50(11):1129-53.
1993: Prusiner S B; Groth D; Serban A; Koehler R; Foster D; Torchia M; Burton D; Yang S L; DeArmond S J
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10608-12.
1993: DeArmond S J; Prusiner S B
The neurochemistry of prion diseases.
Journal of neurochemistry 1993;61(5):1589-601.
1993: Prusiner S B
Transgenetics and cell biology of prion diseases: investigations of PrPSc synthesis and diversity.
British medical bulletin 1993;49(4):873-912.
1993: Gabizon R; Rosenmann H; Meiner Z; Kahana I; Kahana E; Shugart Y; Ott J; Prusiner S B
Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD).
American journal of human genetics 1993;53(4):828-35.
1993: Borchelt D R; Rogers M; Stahl N; Telling G; Prusiner S B
Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor.
Glycobiology 1993;3(4):319-29.
1993: DeArmond S J; Yang S L; Lee A; Bowler R; Taraboulos A; Groth D; Prusiner S B
Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6449-53.
1993: Prusiner S B
Biology of prion diseases.
Journal of acquired immune deficiency syndromes 1993;6(6):663-5.
1993: Scott M; Groth D; Foster D; Torchia M; Yang S L; DeArmond S J; Prusiner S B
Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.
Cell 1993;73(5):979-88.
1993: Rogers M; Yehiely F; Scott M; Prusiner S B
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3182-6.
1993: Prusiner S B; Groth D; Serban A; Stahl N; Gabizon R
Attempts to restore scrapie prion infectivity after exposure to protein denaturants.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2793-7.
1993: Carlson G A; Ebeling C; Torchia M; Westaway D; Prusiner S B
Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse.
Genetics 1993;133(4):979-88.
1993: Stahl N; Baldwin M A; Teplow D B; Hood L; Gibson B W; Burlingame A L; Prusiner S B
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.
Biochemistry 1993;32(8):1991-2002.
1993: Prusiner S B; Füzi M; Scott M; Serban D; Serban H; Taraboulos A; Gabriel J M; Wells G A; Wilesmith J W; Bradley R
Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy.
The Journal of infectious diseases 1993;167(3):602-13.
1993: Prusiner S B
Transgenetic investigations of prion diseases of humans and animals.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;339(1288):239-54.
1993: Gasset M; Baldwin M A; Fletterick R J; Prusiner S B
Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):1-5.
1993: Prusiner S B
Prion encephalopathies of animals and humans.
Developments in biological standardization 1993;80():31-44.
1993: Riesner D; Kellings K; Wiese U; Wulfert M; Mirenda C; Prusiner S B
Prions and nucleic acids: search for "residual" nucleic acids and screening for mutations in the PrP-gene.
Developments in biological standardization 1993;80():173-81.
1993: Kellings K; Meyer N; Mirenda C; Prusiner S B; Riesner D
Analysis of nucleic acids in purified scrapie prion preparations.
Archives of virology. Supplementum 1993;7():215-25.
1992: Prusiner S B
Chemistry and biology of prions.
Biochemistry 1992;31(49):12277-88.
1992: Gasset M; Baldwin M A; Lloyd D H; Gabriel J M; Holtzman D M; Cohen F; Fletterick R; Prusiner S B
Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10940-4.
1992: Prusiner S B
Natural and experimental prion diseases of humans and animals.
Current opinion in neurobiology 1992;2(5):638-47.
1992: Gabriel J M; Oesch B; Kretzschmar H; Scott M; Prusiner S B
Molecular cloning of a candidate chicken prion protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9097-101.
1992: Kretzschmar H A; Neumann M; Riethmüller G; Prusiner S B
Molecular cloning of a mink prion protein gene.
The Journal of general virology 1992;73 ( Pt 10)():2757-61.
1992: Pan K M; Stahl N; Prusiner S B
Purification and properties of the cellular prion protein from Syrian hamster brain.
Protein science : a publication of the Protein Society 1992;1(10):1343-52.
1992: Giaccone G; Verga L; Bugiani O; Frangione B; Serban D; Prusiner S B; Farlow M R; Ghetti B; Tagliavini F
Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9349-53.
1992: Raeber A J; Borchelt D R; Scott M; Prusiner S B
Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.
Journal of virology 1992;66(10):6155-63.
1992: Taraboulos A; Raeber A J; Borchelt D R; Serban D; Prusiner S B
Synthesis and trafficking of prion proteins in cultured cells.
Molecular biology of the cell 1992;3(8):851-63.
1992: Taraboulos A; Jendroska K; Serban D; Yang S L; DeArmond S J; Prusiner S B
Regional mapping of prion proteins in brain.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7620-4.
1992: Borchelt D R; Taraboulos A; Prusiner S B
Evidence for synthesis of scrapie prion proteins in the endocytic pathway.
The Journal of biological chemistry 1992;267(23):16188-99.
1992: Scott M R; Köhler R; Foster D; Prusiner S B
Chimeric prion protein expression in cultured cells and transgenic mice.
Protein science : a publication of the Protein Society 1992;1(8):986-97.
1992: Hecker R; Taraboulos A; Scott M; Pan K M; Yang S L; Torchia M; Jendroska K; DeArmond S J; Prusiner S B
Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters.
Genes & development 1992;6(7):1213-28.
1992: Meiner Z; Halimi M; Polakiewicz R D; Prusiner S B; Gabizon R
Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease.
Neurology 1992;42(7):1355-60.
1992: Stahl N; Baldwin M A; Hecker R; Pan K M; Burlingame A L; Prusiner S B
Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid.
Biochemistry 1992;31(21):5043-53.
1992: Büeler H; Fischer M; Lang Y; Bluethmann H; Lipp H P; DeArmond S J; Prusiner S B; Aguet M; Weissmann C
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein.
Nature 1992;356(6370):577-82.
1992: Hsiao K; Dlouhy S R; Farlow M R; Cass C; Da Costa M; Conneally P M; Hodes M E; Ghetti B; Prusiner S B
Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles.
Nature genetics 1992;1(1):68-71.
1992: Dlouhy S R; Hsiao K; Farlow M R; Foroud T; Conneally P M; Johnson P; Prusiner S B; Hodes M E; Ghetti B
Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene.
Nature genetics 1992;1(1):64-7.
1992: Kellings K; Meyer N; Mirenda C; Prusiner S B; Riesner D
Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis.
The Journal of general virology 1992;73 ( Pt 4)():1025-9.
1992: Kretzschmar H A; Kufer P; Riethmüller G; DeArmond S; Prusiner S B; Schiffer D
Prion protein mutation at codon 102 in an Italian family with Gerstmann-Sträussler-Scheinker syndrome.
Neurology 1992;42(4):809-10.
1992: Prusiner S B
Molecular biology and genetics of neurodegenerative diseases caused by prions.
Advances in virus research 1992;41():241-80.
1991: McKinley M P; Taraboulos A; Kenaga L; Serban D; Stieber A; DeArmond S J; Prusiner S B; Gonatas N
Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells.
Laboratory investigation; a journal of technical methods and pathology 1991;65(6):622-30.
1991: Rogers M; Serban D; Gyuris T; Scott M; Torchia T; Prusiner S B
Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(10):3568-74.
1991: Stahl N; Prusiner S B
Prions and prion proteins.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(13):2799-807.
1991: Stahl N; Baldwin M A; Prusiner S B
Electrospray mass spectrometry of the glycosylinositol phospholipid of the scrapie prion protein.
Cell biology international reports 1991;15(9):853-62.
1991: Jendroska K; Heinzel F P; Torchia M; Stowring L; Kretzschmar H A; Kon A; Stern A; Prusiner S B; DeArmond S J
Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity.
Neurology 1991;41(9):1482-90.
1991: Prusiner S B; DeArmond S J
Molecular biology and pathology of scrapie and the prion diseases of humans.
Brain pathology (Zurich, Switzerland) 1991;1(4):297-310.
1991: Prusiner S B
Molecular biology of prion diseases.
Science (New York, N.Y.) 1991;252(5012):1515-22.
1991: Prusiner S B; Westaway D
Infectious and genetic manifestations of prion diseases.
Molecular plant-microbe interactions : MPMI 1991;4(3):226-33.
1991: Hsiao K K; Cass C; Schellenberg G D; Bird T; Devine-Gage E; Wisniewski H; Prusiner S B
A prion protein variant in a family with the telencephalic form of Gerstmann-Sträussler-Scheinker syndrome.
Neurology 1991;41(5):681-4.
1991: Prusiner S B; Torchia M; Westaway D
Molecular biology and genetics of prions--implications for sheep scrapie, "mad cows" and the BSE epidemic. Historical background.
The Cornell veterinarian 1991;81(2):85-101.
1991: Hsiao K; Meiner Z; Kahana E; Cass C; Kahana I; Avrahami D; Scarlato G; Abramsky O; Prusiner S B; Gabizon R
Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease.
The New England journal of medicine 1991;324(16):1091-7.
1991: McKinley M P; Meyer R K; Kenaga L; Rahbar F; Cotter R; Serban A; Prusiner S B
Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis.
Journal of virology 1991;65(3):1340-51.
1991: Tagliavini F; Prelli F; Ghiso J; Bugiani O; Serban D; Prusiner S B; Farlow M R; Ghetti B; Frangione B
Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.
The EMBO journal 1991;10(3):513-9.
1991: Carlson G A; Hsiao K; Oesch B; Westaway D; Prusiner S B
Genetics of prion infections.
Trends in genetics : TIG 1991;7(2):61-5.
1991: Epstein C J; Foster D B; DeArmond S J; Prusiner S B
Acceleration of scrapie in trisomy 16----diploid aggregation chimeras.
Annals of neurology 1991;29(1):95-7.
1991: Meyer N; Rosenbaum V; Schmidt B; Gilles K; Mirenda C; Groth D; Prusiner S B; Riesner D
Search for a putative scrapie genome in purified prion fractions reveals a paucity of nucleic acids.
The Journal of general virology 1991;72 ( Pt 1)():37-49.
1991: McKinley M P; Prusiner S B
Ultrastructural studies of prions.
Current topics in microbiology and immunology 1991;172():75-91.
1991: Prusiner S B
Novel properties and biology of scrapie prions.
Current topics in microbiology and immunology 1991;172():233-57.
1991: Oesch B; Westaway D; Prusiner S B
Prion protein genes: evolutionary and functional aspects.
Current topics in microbiology and immunology 1991;172():109-24.
1991: Prusiner S B
Molecular biology of prions causing infectious and genetic encephalopathies of humans as well as scrapie of sheep and BSE of cattle.
Developments in biological standardization 1991;75():55-74.
1991: Hsiao K; Scott M; Foster D; DeArmond S J; Groth D; Serban H; Prusiner S B
Spontaneous neurodegeneration in transgenic mice with prion protein codon 101 proline----leucine substitution.
Annals of the New York Academy of Sciences 1991;640():166-70.
1991: Hsiao K; Prusiner S B
Molecular genetics and transgenic model of Gertsmann-Sträussler-Scheinker disease.
Alzheimer disease and associated disorders 1991;5(3):155-62.
1991: Prusiner S B
Molecular biology and transgenetics of prion diseases.
Critical reviews in biochemistry and molecular biology 1991;26(5-6):397-438.
1991: Prusiner S B
Prion biology and diseases.
Harvey lectures 1991;87():85-114.
1990: Hsiao K; Prusiner S B
Inherited human prion diseases.
Neurology 1990;40(12):1820-7.
1990: Hsiao K K; Scott M; Foster D; Groth D F; DeArmond S J; Prusiner S B
Spontaneous neurodegeneration in transgenic mice with mutant prion protein.
Science (New York, N.Y.) 1990;250(4987):1587-90.
1990: Baldwin M A; Stahl N; Reinders L G; Gibson B W; Prusiner S B; Burlingame A L
Permethylation and tandem mass spectrometry of oligosaccharides having free hexosamine: analysis of the glycoinositol phospholipid anchor glycan from the scrapie prion protein.
Analytical biochemistry 1990;191(1):174-82.
1990: Taraboulos A; Rogers M; Borchelt D R; McKinley M P; Scott M; Serban D; Prusiner S B
Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8262-6.
1990: Snow A D; Wight T N; Nochlin D; Koike Y; Kimata K; DeArmond S J; Prusiner S B
Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie.
Laboratory investigation; a journal of technical methods and pathology 1990;63(5):601-11.
1990: Prusiner S B; Scott M; Foster D; Pan K M; Groth D; Mirenda C; Torchia M; Yang S L; Serban D; Carlson G A
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.
Cell 1990;63(4):673-86.
1990: Prusiner S B
Novel structure and genetics of prions causing neurodegeneration in humans and animals.
Biologicals : journal of the International Association of Biological Standardization 1990;18(4):247-62.
1990: Rogers M; Taraboulos A; Scott M; Groth D; Prusiner S B
Intracellular accumulation of the cellular prion protein after mutagenesis of its Asn-linked glycosylation sites.
Glycobiology 1990;1(1):101-9.
1990: Stahl N; Baldwin M A; Burlingame A L; Prusiner S B
Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein.
Biochemistry 1990;29(38):8879-84.
1990: Westaway D; Prusiner S B
Link between scrapie and BSE?
Nature 1990;346(6280):113.
1990: Oesch B; Teplow D B; Stahl N; Serban D; Hood L E; Prusiner S B
Identification of cellular proteins binding to the scrapie prion protein.
Biochemistry 1990;29(24):5848-55.
1990: Stahl N; Borchelt D R; Prusiner S B
Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C.
Biochemistry 1990;29(22):5405-12.
1990: Taraboulos A; Serban D; Prusiner S B
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells.
The Journal of cell biology 1990;110(6):2117-32.
1990: Lopez C D; Yost C S; Prusiner S B; Myers R M; Lingappa V R
Unusual topogenic sequence directs prion protein biogenesis.
Science (New York, N.Y.) 1990;248(4952):226-9.
1990: Lowenstein D H; Butler D A; Westaway D; McKinley M P; DeArmond S J; Prusiner S B
Three hamster species with different scrapie incubation times and neuropathological features encode distinct prion proteins.
Molecular and cellular biology 1990;10(3):1153-63.
1990: Borchelt D R; Scott M; Taraboulos A; Stahl N; Prusiner S B
Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells.
The Journal of cell biology 1990;110(3):743-52.
1990: Boylan K B; Takahashi N; Paty D W; Sadovnick A D; Diamond M; Hood L E; Prusiner S B
DNA length polymorphism 5' to the myelin basic protein gene is associated with multiple sclerosis.
Annals of neurology 1990;27(3):291-7.
1990: Gabizon R; Prusiner S B
Prion liposomes.
The Biochemical journal 1990;266(1):1-14.
1990: Yost C S; Lopez C D; Prusiner S B; Myers R M; Lingappa V R
Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein.
Nature 1990;343(6259):669-72.
1990: Serban D; Taraboulos A; DeArmond S J; Prusiner S B
Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins.
Neurology 1990;40(1):110-7.
1990: Boylan K B; Ayres T M; Popko B; Takahashi N; Hood L E; Prusiner S B
Repetitive DNA (TGGA)n 5' to the human myelin basic protein gene: a new form of oligonucleotide repetitive sequence showing length polymorphism.
Genomics 1990;6(1):16-22.
1990: Prusiner S B; DeArmond S J
Prion diseases of the central nervous system.
Monographs in pathology 1990;(32):86-122.
1990: McKinley M P; Longo F M; Valletta J S; Rahbar F; Neve R L; Prusiner S B; Mobley W C
Nerve growth factor induces gene expression of the prion protein and beta-amyloid protein precursor in the developing hamster central nervous system.
Progress in brain research 1990;86():227-38.
1989: Carlson G A; Westaway D; DeArmond S J; Peterson-Torchia M; Prusiner S B
Primary structure of prion protein may modify scrapie isolate properties.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7475-9.
1989: Endo T; Groth D; Prusiner S B; Kobata A
Diversity of oligosaccharide structures linked to asparagines of the scrapie prion protein.
Biochemistry 1989;28(21):8380-8.
1989: McKinley M P; DeArmond S J; Torchia M; Mobley W C; Prusiner S B
Acceleration of scrapie in neonatal Syrian hamsters.
Neurology 1989;39(10):1319-24.
1989: Westaway D; Carlson G A; Prusiner S B
Unraveling prion diseases through molecular genetics.
Trends in neurosciences 1989;12(6):221-7.
1989: Hsiao K; Baker H F; Crow T J; Poulter M; Owen F; Terwilliger J D; Westaway D; Ott J; Prusiner S B
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome.
Nature 1989;338(6213):342-5.
1989: Owen F; Poulter M; Lofthouse R; Collinge J; Crow T J; Risby D; Baker H F; Ridley R M; Hsiao K; Prusiner S B
Insertion in prion protein gene in familial Creutzfeldt-Jakob disease.
Lancet 1989;1(8628):51-2.
1989: De Armond S J; Gonzales M; Mobley W C; Kon A A; Stern A; Prusiner H; Prusiner S B
PrPSc in scrapie-infected hamster brain is spatially and temporally related to histopathology and infectivity titer.
Progress in clinical and biological research 1989;317():601-18.
1989: Gabizon R; McKinley M P; Groth D; Westaway D; DeArmond S J; Carlson G A; Prusiner S B
Immunoaffinity purification and neutralization of scrapie prions.
Progress in clinical and biological research 1989;317():583-600.
1989: Prusiner S B
Scrapie prions.
Annual review of microbiology 1989;43():345-74.
1989: Prusiner S B
Creutzfeldt-Jakob disease and scrapie prions.
Alzheimer disease and associated disorders 1989;3(1-2):52-78.
1989: Snow A D; Kisilevsky R; Willmer J; Prusiner S B; DeArmond S J
Sulfated glycosaminoglycans in amyloid plaques of prion diseases.
Acta neuropathologica 1989;77(4):337-42.
1988: Carlson G A; Goodman P A; Lovett M; Taylor B A; Marshall S T; Peterson-Torchia M; Westaway D; Prusiner S B
Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time.
Molecular and cellular biology 1988;8(12):5528-40.
1988: Mobley W C; Neve R L; Prusiner S B; McKinley M P
Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9811-5.
1988: Roberts G W; Lofthouse R; Allsop D; Landon M; Kidd M; Prusiner S B; Crow T J
CNS amyloid proteins in neurodegenerative diseases.
Neurology 1988;38(10):1534-40.
1988: Turk E; Teplow D B; Hood L E; Prusiner S B
Purification and properties of the cellular and scrapie hamster prion proteins.
European journal of biochemistry / FEBS 1988;176(1):21-30.
1988: Gabizon R; McKinley M P; Groth D; Prusiner S B
Immunoaffinity purification and neutralization of scrapie prion infectivity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(18):6617-21.
1988: Bellinger-Kawahara C G; Kempner E; Groth D; Gabizon R; Prusiner S B
Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da.
Virology 1988;164(2):537-41.
1988: Butler D A; Scott M R; Bockman J M; Borchelt D R; Taraboulos A; Hsiao K K; Kingsbury D T; Prusiner S B
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins.
Journal of virology 1988;62(5):1558-64.
1988: Gabizon R; McKinley M P; Groth D F; Kenaga L; Prusiner S B
Properties of scrapie prion protein liposomes.
The Journal of biological chemistry 1988;263(10):4950-5.
1988: Scott M R; Butler D A; Bredesen D E; Wälchli M; Hsiao K K; Prusiner S B
Prion protein gene expression in cultured cells.
Protein engineering 1988;2(1):69-76.
1988: Barry R A; Vincent M T; Kent S B; Hood L E; Prusiner S B
Characterization of prion proteins with monospecific antisera to synthetic peptides.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(4):1188-93.
1988: Oesch B; Groth D F; Prusiner S B; Weissmann C
Search for a scrapie-specific nucleic acid: a progress report.
Ciba Foundation symposium 1988;135():209-23.
1988: Prusiner S B
Molecular structure, biology, and genetics of prions.
Advances in virus research 1988;35():83-136.
1988: Carlson G A; Westaway D; Goodman P A; Peterson M; Marshall S T; Prusiner S B
Genetic control of prion incubation period in mice.
Ciba Foundation symposium 1988;135():84-99.
1988: Prusiner S B; Stahl N; DeArmond S J
Novel mechanisms of degeneration of the central nervous system--prion structure and biology.
Ciba Foundation symposium 1988;135():239-60.
1988: Gabizon R; McKinley M P; Prusiner S B
Properties of scrapie prion proteins in liposomes and amyloid rods.
Ciba Foundation symposium 1988;135():182-96.
1988: McKinley M P; Lingappa V R; Prusiner S B
Developmental regulation of prion protein mRNA in brain.
Ciba Foundation symposium 1988;135():101-16.
1987: Prusiner S B
Prions and neurodegenerative diseases.
The New England journal of medicine 1987;317(25):1571-81.
1987: Hay B; Prusiner S B; Lingappa V R
Evidence for a secretory form of the cellular prion protein.
Biochemistry 1987;26(25):8110-5.
1987: Wiley C A; Burrola P G; Buchmeier M J; Wooddell M K; Barry R A; Prusiner S B; Lampert P W
Immuno-gold localization of prion filaments in scrapie-infected hamster brains.
Laboratory investigation; a journal of technical methods and pathology 1987;57(6):646-56.
1987: Braun M J; Gonda M A; George D G; Bazan J F; Fletterick R J; Prusiner S B
The burden of proof in linking AIDS to scrapie.
Nature 1987;330(6148):525-6.
1987: Westaway D; Goodman P A; Mirenda C A; McKinley M P; Carlson G A; Prusiner S B
Distinct prion proteins in short and long scrapie incubation period mice.
Cell 1987;51(4):651-62.
1987: Stahl N; Borchelt D R; Hsiao K; Prusiner S B
Scrapie prion protein contains a phosphatidylinositol glycolipid.
Cell 1987;51(2):229-40.
1987: Bellinger-Kawahara C; Diener T O; McKinley M P; Groth D F; Smith D R; Prusiner S B
Purified scrapie prions resist inactivation by procedures that hydrolyze, modify, or shear nucleic acids.
Virology 1987;160(1):271-4.
1987: DeArmond S J; Mobley W C; DeMott D L; Barry R A; Beckstead J H; Prusiner S B
Changes in the localization of brain prion proteins during scrapie infection.
Neurology 1987;37(8):1271-80.
1987: Kitamoto T; Ogomori K; Tateishi J; Prusiner S B
Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.
Laboratory investigation; a journal of technical methods and pathology 1987;57(2):230-6.
1987: Hogan R N; Baringer J R; Prusiner S B
Scrapie infection diminishes spines and increases varicosities of dendrites in hamsters: a quantitative Golgi analysis.
Journal of neuropathology and experimental neurology 1987;46(4):461-73.
1987: Bockman J M; Prusiner S B; Tateishi J; Kingsbury D T
Immunoblotting of Creutzfeldt-Jakob disease prion proteins: host species-specific epitopes.
Annals of neurology 1987;21(6):589-95.
1987: Gabizon R; McKinley M P; Prusiner S B
Purified prion proteins and scrapie infectivity copartition into liposomes.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(12):4017-21.
1987: McKinley M P; Hay B; Lingappa V R; Lieberburg I; Prusiner S B
Developmental expression of prion protein gene in brain.
Developmental biology 1987;121(1):105-10.
1987: Boylan K B; Takahashi N; Diamond M; Hood L E; Prusiner S B
DNA length polymorphism located 5' to the human myelin basic protein gene.
American journal of human genetics 1987;40(5):387-400.
1987: Prusiner S B
Prion diseases and central nervous system degeneration.
Clinical research 1987;35(3):177-91.
1987: Prusiner S B; DeArmond S J
Prions causing nervous system degeneration.
Laboratory investigation; a journal of technical methods and pathology 1987;56(4):349-63.
1987: Hay B; Barry R A; Lieberburg I; Prusiner S B; Lingappa V R
Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]
Molecular and cellular biology 1987;7(2):914-20.
1987: Fernando Bazan J; Fletterick R J; Prusiner S B
AIDS virus and scrapie protein genes.
Nature 1987;325(6105):581.
1987: Bazan J F; Fletterick R J; McKinley M P; Prusiner S B
Predicted secondary structure and membrane topology of the scrapie prion protein.
Protein engineering 1987;1(2):125-35.
1987: Bellinger-Kawahara C; Cleaver J E; Diener T O; Prusiner S B
Purified scrapie prions resist inactivation by UV irradiation.
Journal of virology 1987;61(1):159-66.
1987: Prusiner S B
Prions causing degenerative neurological diseases.
Annual review of medicine 1987;38():381-98.
1987: Prusiner S B; Gabizon R; McKinley M P
On the biology of prions.
Acta neuropathologica 1987;72(4):299-314.
1986: Prusiner S B
Prions are novel infectious pathogens causing scrapie and Creutzfeldt-Jakob disease.
BioEssays : news and reviews in molecular, cellular and developmental biology 1986;5(6):281-6.
1986: Roberts G W; Lofthouse R; Brown R; Crow T J; Barry R A; Prusiner S B
Prion-protein immunoreactivity in human transmissible dementias.
The New England journal of medicine 1986;315(19):1231-3.
1986: Crook R B; Prusiner S B
Vasoactive intestinal peptide stimulates cyclic AMP metabolism in choroid plexus epithelial cells.
Brain research 1986;384(1):138-44.
1986: Barry R A; Prusiner S B
Monoclonal antibodies to the cellular and scrapie prion proteins.
The Journal of infectious diseases 1986;154(3):518-21.
1986: Kretzschmar H A; Stowring L E; Westaway D; Stubblebine W H; Prusiner S B; Dearmond S J
Molecular cloning of a human prion protein cDNA.
DNA (Mary Ann Liebert, Inc.) 1986;5(4):315-24.
1986: Kitamoto T; Tateishi J; Tashima T; Takeshita I; Barry R A; DeArmond S J; Prusiner S B
Amyloid plaques in Creutzfeldt-Jakob disease stain with prion protein antibodies.
Annals of neurology 1986;20(2):204-8.
1986: Carlson G A; Kingsbury D T; Goodman P A; Coleman S; Marshall S T; DeArmond S; Westaway D; Prusiner S B
Linkage of prion protein and scrapie incubation time genes.
Cell 1986;46(4):503-11.
1986: Basler K; Oesch B; Scott M; Westaway D; Wälchli M; Groth D F; McKinley M P; Prusiner S B; Weissmann C
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene.
Cell 1986;46(3):417-28.
1986: McKinley M P; Braunfeld M B; Bellinger C G; Prusiner S B
Molecular characteristics of prion rods purified from scrapie-infected hamster brains.
The Journal of infectious diseases 1986;154(1):110-20.
1986: Barry R A; Kent S B; McKinley M P; Meyer R K; DeArmond S J; Hood L E; Prusiner S B
Scrapie and cellular prion proteins share polypeptide epitopes.
The Journal of infectious diseases 1986;153(5):848-54.
1986: Meyer R K; McKinley M P; Bowman K A; Braunfeld M B; Barry R A; Prusiner S B
Separation and properties of cellular and scrapie prion proteins.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2310-4.
1986: Westaway D; Prusiner S B
Conservation of the cellular gene encoding the scrapie prion protein.
Nucleic acids research 1986;14(5):2035-44.
1986: Crook R B; Farber M B; Prusiner S B
H2 histamine receptors on the epithelial cells of choroid plexus.
Journal of neurochemistry 1986;46(2):489-93.
1986: Kretzschmar H A; Prusiner S B; Stowring L E; DeArmond S J
Scrapie prion proteins are synthesized in neurons.
The American journal of pathology 1986;122(1):1-5.
1986: McKinley M P; Prusiner S B
Biology and structure of scrapie prions.
International review of neurobiology 1986;28():1-57.
1986: Hogan R N; Bowman K A; Baringer J R; Prusiner S B
Replication of scrapie prions in hamster eyes precedes retinal degeneration.
Ophthalmic research 1986;18(4):230-5.
1985: Prusiner S B; Cochran S P; Alpers M P
Transmission of scrapie in hamsters.
The Journal of infectious diseases 1985;152(5):971-8.
1985: Monteiro M L; Swanson R A; Coppeto J R; Cuneo R A; DeArmond S J; Prusiner S B
A microangiopathic syndrome of encephalopathy, hearing loss, and retinal arteriolar occlusions.
Neurology 1985;35(8):1113-21.
1985: Takahashi N; Roach A; Teplow D B; Prusiner S B; Hood L
Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons.
Cell 1985;42(1):139-48.
1985: Barry R A; McKinley M P; Bendheim P E; Lewis G K; DeArmond S J; Prusiner S B
Antibodies to the scrapie protein decorate prion rods.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(1):603-13.
1985: DeArmond S J; McKinley M P; Barry R A; Braunfeld M B; McColloch J R; Prusiner S B
Identification of prion amyloid filaments in scrapie-infected brain.
Cell 1985;41(1):221-35.
1985: Bolton D C; Meyer R K; Prusiner S B
Scrapie PrP 27-30 is a sialoglycoprotein.
Journal of virology 1985;53(2):596-606.
1985: Bendheim P E; Bockman J M; McKinley M P; Kingsbury D T; Prusiner S B
Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(4):997-1001.
1985: Bockman J M; Kingsbury D T; McKinley M P; Bendheim P E; Prusiner S B
Creutzfeldt-Jakob disease prion proteins in human brains.
The New England journal of medicine 1985;312(2):73-8.
1985: Prusiner S B; Barry R A; McKinley M P; Bellinger C G; Meyer R K; DeArmond S J; Kingsbury D T
Scrapie and Creutzfeldt-Jakob disease prions.
Microbiological sciences 1985;2(2):33-9.
1985: Prusiner S B; Kingsbury D T
Prions--infectious pathogens causing the spongiform encephalopathies.
CRC critical reviews in clinical neurobiology 1985;1(3):181-200.
1985: Prusiner S B
Scrapie prions, brain amyloid, and senile dementia.
Current topics in cellular regulation 1985;26():79-95.
1984: Bolton D C; McKinley M P; Prusiner S B
Molecular characteristics of the major scrapie prion protein.
Biochemistry 1984;23(25):5898-906.
1984: Prusiner S B
Prions.
Scientific American 1984;251(4):50-9.
1984: Friedland R P; Prusiner S B; Jagust W J; Budinger T F; Davis R L
Bitemporal hypometabolism in Creutzfeldt-Jakob disease measured by positron emission tomography with [18F]-2-fluorodeoxyglucose.
Journal of computer assisted tomography 1984;8(5):978-81.
1984: Prusiner S B; Groth D F; Bolton D C; Kent S B; Hood L E
Purification and structural studies of a major scrapie prion protein.
Cell 1984;38(1):127-34.
1984: Bendheim P E; Barry R A; DeArmond S J; Stites D P; Prusiner S B
Antibodies to a scrapie prion protein.
Nature 1984;310(5976):418-21.
1984: Prusiner S B
Some speculations about prions, amyloid, and Alzheimer's disease.
The New England journal of medicine 1984;310(10):661-3.
1984: Crook R B; Farber M B; Prusiner S B
Hormones and neurotransmitters control cyclic AMP metabolism in choroid plexus epithelial cells.
Journal of neurochemistry 1984;42(2):340-50.
1984: Prusiner S B
Prions: novel infectious pathogens.
Advances in virus research 1984;29():1-56.
1983: Prusiner S B; McKinley M P; Bowman K A; Bolton D C; Bendheim P E; Groth D F; Glenner G G
Scrapie prions aggregate to form amyloid-like birefringent rods.
Cell 1983;35(2 Pt 1):349-58.
1983: Hogan R N; Kingsbury D T; Baringer J R; Prusiner S B
Retinal degeneration in experimental Creutzfeldt-Jakob disease.
Laboratory investigation; a journal of technical methods and pathology 1983;49(6):708-15.
1983: McKinley M P; Bolton D C; Prusiner S B
A protease-resistant protein is a structural component of the scrapie prion.
Cell 1983;35(1):57-62.
1983: Roach A; Boylan K; Horvath S; Prusiner S B; Hood L E
Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice.
Cell 1983;34(3):799-806.
1983: Baringer J R; Bowman K A; Prusiner S B
Replication of the scrapie agent in hamster brain precedes neuronal vacuolation.
Journal of neuropathology and experimental neurology 1983;42(5):539-47.
1983: Kingsbury D T; Kasper K C; Stites D P; Watson J D; Hogan R N; Prusiner S B
Genetic control of scrapie and Creutzfeldt-Jakob disease in mice.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(1):491-6.
1983: McKinley M P; Masiarz F R; Isaacs S T; Hearst J E; Prusiner S B
Resistance of the scrapie agent to inactivation by psoralens.
Photochemistry and photobiology 1983;37(5):539-45.
1982: Prusiner S B; Bolton D C; Groth D F; Bowman K A; Cochran S P; McKinley M P
Further purification and characterization of scrapie prions.
Biochemistry 1982;21(26):6942-50.
1982: Bolton D C; McKinley M P; Prusiner S B
Identification of a protein that purifies with the scrapie prion.
Science (New York, N.Y.) 1982;218(4579):1309-11.
1982: Kasper K C; Stites D P; Bowman K A; Panitch H; Prusiner S B
Immunological studies of scrapie infection.
Journal of neuroimmunology 1982;3(3):187-201.
1982: Diener T O; McKinley M P; Prusiner S B
Viroids and prions.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5220-4.
1982: Prusiner S B
Research on scrapie.
Lancet 1982;2(8296):494-5.
1982: Prusiner S B; Gajdusek C; Alpers M P
Kuru with incubation periods exceeding two decades.
Annals of neurology 1982;12(1):1-9.
1982: Prusiner S B; Cochran S P; Groth D F; Downey D E; Bowman K A; Martinez H M
Measurement of the scrapie agent using an incubation time interval assay.
Annals of neurology 1982;11(4):353-8.
1982: Prusiner S B
Novel proteinaceous infectious particles cause scrapie.
Science (New York, N.Y.) 1982;216(4542):136-44.
1981: McKinley M P; Masiarz F R; Prusiner S B
Reversible chemical modification of the scrapie agent.
Science (New York, N.Y.) 1981;214(4526):1259-61.
1981: Prusiner S B; McKinley M P; Groth D F; Bowman K A; Mock N I; Cochran S P; Masiarz F R
Scrapie agent contains a hydrophobic protein.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(11):6675-9.
1981: Crook R B; Kasagami H; Prusiner S B
Culture and characterization of epithelial cells from bovine choroid plexus.
Journal of neurochemistry 1981;37(4):845-54.
1981: Mamelok R D; Macrae D R; Benet L Z; Prusiner S B
Membrane populations of bovine choroid plexus: separation by density gradient centrifugation in modified colloidal silica.
Journal of neurochemistry 1981;37(3):768-74.
1981: Prusiner S B; Groth D F; McKinley M P; Cochran S P; Bowman K A; Kasper K C
Thiocyanate and hydroxyl ions inactivate the scrapie agent.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4606-10.
1981: Baringer J R; Prusiner S B; Wong J S
Scrapie-associated particles in postsynaptic processes. Further ultrastructural studies.
Journal of neuropathology and experimental neurology 1981;40(3):281-8.
1981: Mamelok R D; Macrae D R; Hittelman K; Hoefer J P; Prusiner S B
Kinetics of D-glucose transport into renal membrane vesicles: measurements using a vacuum manifold apparatus.
Journal of biochemical and biophysical methods 1981;4(3-4):147-53.
1981: Hogan R N; Baringer J R; Prusiner S B
Progressive retinal degeneration in scrapie-infected hamsters: a light and electron microscopic analysis.
Laboratory investigation; a journal of technical methods and pathology 1981;44(1):34-42.
1981: Prusiner S B; Cochran S P; Downey D E; Groth D F
Determination of scrapie agent titer from incubation period measurements in hamsters.
Advances in experimental medicine and biology 1981;134():385-99.
1981: Prusiner S B
Disorders of glutamate metabolism and neurological dysfunction.
Annual review of medicine 1981;32():521-42.
1981: Kasper K C; Bowman K; Stites D P; Prusiner S B
Toward development of assays for scrapie-specific antibodies.
Advances in experimental medicine and biology 1981;134():401-13.
1980: Hadlow W J; Prusiner S B; Kennedy R C; Race R E
Brain tissue from persons dying of Creutzfeldt-Jakob disease causes scrapie-like encephalopathy in goats.
Annals of neurology 1980;8(6):628-32.
1980: Prusiner S B; Groth D F; Cochran S P; McKinley M P; Masiarz F R
Gel electrophoresis and glass permeation chromatography of the hamster scrapie agent after enzymatic digestion and detergent extraction.
Biochemistry 1980;19(21):4892-8.
1980: Prusiner S B; Groth D F; Cochran S P; Masiarz F R; McKinley M P; Martinez H M
Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent.
Biochemistry 1980;19(21):4883-91.
1980: Prusiner S B; Garfin D E; Cochran S P; McKinley M P; Groth D F; Hadlow W J; Race R E; Eklund C M
Experimental scrapie in the mouse: electrophoretic and sedimentation properties of the partially purified agent.
Journal of neurochemistry 1980;35(3):574-82.
1980: Chatigny M A; Prusiner S B
Biohazards of investigations on the transmissible spongiform encephalopathies.
Reviews of infectious diseases 1980;2(5):713-24.
1980: Prusiner S B; Groth D F; Bildstein C; Masiarz F R; McKinley M P; Cochran S P
Electrophoretic properties of the scrapie agent in agarose gels.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(5):2984-8.
1980: Mamelok R D; Groth D F; Prusiner S B
Separation of membrane-bound gamma-glutamyl transpeptidase from brush border transport and enzyme activities.
Biochemistry 1980;19(11):2367-73.
1980: Prusiner S B; Cochran S P; Baringer J R; Groth D; Masiarz F; McKinley M; Bildstein C; Garfin D; Hadlow W J; Race R E; Eklund C M
Slow viruses: molecular properties of the agents causing scrapie in mice and hamsters.
Progress in clinical and biological research 1980;39():73-89.
1979: Chatigny M A; Dunn S; Ishimaru K; Eagleson J A; Prusiner S B
Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge.
Applied and environmental microbiology 1979;38(5):934-9.
1978: Prusiner S B; Hadlow W J; Eklund C M; Race R E; Cochran S P
Sedimentation characteristics of the scrapie agent from murine spleen and brain.
Biochemistry 1978;17(23):4987-92.
1978: Prusiner S B; Hadlow W J; Garfin D E; Cochran S P; Baringer J R; Race R E; Eklund C M
Partial purification and evidence for multiple molecular forms of the scrapie agent.
Biochemistry 1978;17(23):4993-9.
1978: Hittelman K; Mamelok R D; Prusiner S B
Preservation by freezing of glucose and alanine transport into kidney membrane vesicles.
Analytical biochemistry 1978;89(2):324-31.
1978: Baringer J R; Prusiner S B
Experimental scrapie in mice: ultrastructural observations.
Annals of neurology 1978;4(3):205-11.
1978: Garfin D E; Stites D P; Perlman J D; Cochran S P; Prusiner S B
Mitogen stimulation of splenocytes from mice infected with scrapie agent.
The Journal of infectious diseases 1978;138(3):396-400.
1978: Garfin D E; Stites D P; Zitnik L A; Prusiner S B
Suppression of polyclonal B cell activation in scrapie-infected C3H/HeJ mice.
Journal of immunology (Baltimore, Md. : 1950) 1978;120(6):1986-90.
1978: Prusiner P E; Prusiner S B
Modulation of gamma-glutamyl transpeptidase activity from bovine choroid plexus.
Journal of neurochemistry 1978;30(6):1261-7.
1978: Prusiner P E; Prusiner S B
Partial purification and kinetics of gamma-glutamyl transpeptidase from bovine choroid plexus.
Journal of neurochemistry 1978;30(6):1253-9.
1978: Prusiner S B
An approach to the isolation of biological particles using sedimentation analysis.
The Journal of biological chemistry 1978;253(3):916-21.
1978: Prusiner S B; Garfin D E; Cochran S P; Baringer J R; Hadlow W J; Eklund C M; Race R E
Evidence for hydrophobic domains on the surface of the scrapie agent.
Transactions of the American Neurological Association 1978;103():62-4.
1977: Prusiner S B; Hadlow W J; Eklund C M; Race R E
Sedimentation properties of the scrapie agent.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(10):4656-60.
1977: Kirk G; Prusiner S B
Comparative studies on membranes from bovine choroid plexus and rat kidney cortex.
Life sciences 1977;21(6):833-40.
1977: Raskin N H; Prusiner S
Carotidynia.
Neurology 1977;27(1):43-6.
1976: Prusiner S; Doak C W; Kirk G
A novel mechanism for group translocation: substrate-product reutilization by gamma-glutamyl transpeptidase in peptide and amino acid transport.
Journal of cellular physiology 1976;89(4):853-63.
1976: Prusiner S; Stadtman E R
Regulation of glutaminase B in Escherichia coli. III. Control by nucleotides and divalent cations.
The Journal of biological chemistry 1976;251(11):3463-9.
1976: Prusiner S; Stadtman E R
Regulation of glutaminase B in Escherichia coli. II. Modulaltion of activity by carbosylate and borate ions.
The Journal of biological chemistry 1976;251(11):3457-62.
1976: Prusiner S; Davis J N; Stadtman E R
Regulation of glutaminase B in Escherichia coli. I. Purification, properties, and cold lability.
The Journal of biological chemistry 1976;251(11):3447-56.
1975: Prusiner S
Regulation of glutaminase levels in Escherichia coli.
Journal of bacteriology 1975;123(3):992-9.
1974: Deuel T F; Prusiner S
Regulation of glutamine synthetase from Bacillus subtilis by divalent cations, feedback inhibitors, and L-glutamine.
The Journal of biological chemistry 1974;249(1):257-64.
1973: Davis J N; Prusiner S
Stain for glutaminase activity.
Analytical biochemistry 1973;54(1):272-5.
1972: Prusiner S; Miller R E; Valentine R C
Adenosine 3':5'-cyclic monophosphate control of the enzymes of glutamine metabolism in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1972;69(10):2922-6.
1971: Prusiner S; Stadtman E R
On the regulation of glutaminase in E. coli: metabolite control.
Biochemical and biophysical research communications 1971;45(6):1474-81.
1971: Prusiner S B; Milner L S; Long C W; Myers M L
Vacuum manifold for rapid assay of enzymes using radioactive tracers and ion exchange chromatography.
The Review of scientific instruments 1971;42(4):493-4.
1970: Prusiner S; Milner L
A rapid radioactive assay for glutamine synthetase, glutaminase, asparagine synthetase, and asparaginase.
Analytical biochemistry 1970;37(2):429-38.
1970: Lindberg O; Prusiner S B; Cannon B; Ching T M; Eisenhardt R H
Metabolic control in isolated brown fat cells.
Lipids 1970;5(2):204-9.
1970: Williamson J R; Prusiner S; Olson M S; Fukami M
Control of metabolism in brown adipose tissue.
Lipids 1970;5(1):1-14.
1970: Prusiner S
Spectroscopic evidence for the control of respiration prior to phosphorylation in hamster brown fat cells.
The Journal of biological chemistry 1970;245(2):382-9.
1970: Reulen H J; Steude U; Brendel W; Hilber C; Prusiner S
[Energetic disturbance of cation transport as a cause of intracellular brain edema]
Acta neurochirurgica 1970;22(2):129-66.
1968: Prusiner S; Wolfson S K
Hypothermic protection against cerebral edema of ischemia.
Archives of neurology 1968;19(6):623-7.
1968: Prusiner S B; Cannon B; Ching T M; Lindberg O
Oxidative metabolism in cells isolated from brown adipose tissue. 2. Catecholamine regulated respiratory control.
European journal of biochemistry / FEBS 1968;7(1):51-7.
1968: Prusiner S B; Cannon B; Lindberg O
Oxidative metabolism in cells isolated from brown adipose tissue. 1. Catecholamine and fatty acid stimulation of respiration.
European journal of biochemistry / FEBS 1968;6(1):15-22.
1968: Prusiner S; Poe M
Thermodynamic cosiderations of mammalian thermogenesis.
Nature 1968;220(5164):235-7.
1968: Prusiner S B; Eisenhardt R H; Rylander E; Lindberg O
The regulation of oxidative metabolism of isolated brown fat cells.
Biochemical and biophysical research communications 1968;30(5):508-15.
1968: Prusiner S; Williamson J R; Chance B; Paddle B M
Pyridine nucleotide changes during thermogenesis in brown fat tissue in vivo.
Archives of biochemistry and biophysics 1968;123(2):368-77.
1965: Prusiner S B; Moskovitz P A; Wolfson S K
Relationship of acidemia to cerebral edema.
Archives of surgery (Chicago, Ill. : 1960) 1965;91(6):902-5.

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