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Lajos Pusztai

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Windy Dean-Colomb; Daniel J Booser; Terrie G Gornet; Beverly C Handy; Kenneth R Hess; Gabriel N Hortobagyi; Nuhad Ibrahim; Stacy L Moulder; Lajos Pusztai; Vicente Valero; Elliana Young; Francisco J Esteva
Elevated serum P1NP predicts development of bone metastasis and survival in early-stage breast cancer.
Ashley M Holder; Gabriel N Hortobagyi; Gordon B Mills; Lajos Pusztai; Argun Akcakanat; Huiqin Chen; Kim-Anh Do; W Fraser Symmans; Ana M Gonzalez-Angulo; Funda Meric-Bernstam
High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients.
Yann Delpech; K R Hess; Gabriel N Hortobagyi; L Hsu; D Mauro; R Natowicz; M Ayers; Emmanuel Barranger; Charles Coutant; Roman Rouzier; Y Wu; Lajos Pusztai
Ki67 expression in the primary tumor predicts for clinical benefit and time to progression on first-line endocrine therapy in estrogen receptor-positive metastatic breast cancer.

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2013: Windy Dean-Colomb; Daniel J Booser; Terrie G Gornet; Beverly C Handy; Kenneth R Hess; Gabriel N Hortobagyi; Nuhad Ibrahim; Stacy L Moulder; Lajos Pusztai; Vicente Valero; Elliana Young; Francisco J Esteva
Elevated serum P1NP predicts development of bone metastasis and survival in early-stage breast cancer.
Breast cancer research and treatment 2013;137(2):631-6.
2013: Ashley M Holder; Gabriel N Hortobagyi; Gordon B Mills; Lajos Pusztai; Argun Akcakanat; Huiqin Chen; Kim-Anh Do; W Fraser Symmans; Ana M Gonzalez-Angulo; Funda Meric-Bernstam
High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients.
Breast cancer research and treatment 2013;137(1):319-27.
2012: Yann Delpech; K R Hess; Gabriel N Hortobagyi; L Hsu; D Mauro; R Natowicz; M Ayers; Emmanuel Barranger; Charles Coutant; Roman Rouzier; Y Wu; Lajos Pusztai
Ki67 expression in the primary tumor predicts for clinical benefit and time to progression on first-line endocrine therapy in estrogen receptor-positive metastatic breast cancer.
Breast cancer research and treatment 2012;135(2):619-27.
2012: Libero Santarpia; Katherine Stemke-Hale; W Fraser Symmans; Vicente Valero; Tatiana Vidaurre; Bailiang Wang; Elliana J Young; Yuan Qi; Daniel J Booser; Giulia Bottai; Angelo Di Leo; Henry Gomez; Ana M Gonzalez-Angulo; Beth Hellerstedt; Frankie A Holmes; Gabriel N Hortobagyi; Joyce O'Shaughnessy; John Pippen; Lajos Pusztai
Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers.
Breast cancer research and treatment 2012;134(1):333-43.
2012: Takayuki Iwamoto; Kimberly Koenig; Junji Matsuoka; James L Murray; Daniel J Booser; Francisco J Esteva; Christos Hatzis; Gabriel N Hortobagyi; Yuan Qi; Weiwei Shi; W Fraser Symmans; Naoto T Ueno; Vicente Valero; Elliana J Yang; Jie Zhang; Lajos Pusztai
Estrogen receptor (ER) mRNA and ER-related gene expression in breast cancers that are 1% to 10% ER-positive by immunohistochemistry.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(7):729-34.
2012: Phuong K Morrow; D Michelle Nikoloff; Lajos Pusztai; Ruben Serna; Grantland R Hillman; Gabriel Hortobagyi; Rui Li; Laura Michaud; Kristine Broglio; Marcel Fontecha; Ana M Gonzalez-Angulo
Effect of CYP2D6 polymorphisms on breast cancer recurrence.
Cancer 2012;118(5):1221-7.
2012: Ana M Gonzalez-Angulo; Gabriel N Hortobagyi; Takayuki Iwamoto; Shuying Liu; Funda Meric-Bernstam; Gordon B Mills; Huiqin Chen; Kim-Anh Do; W Fraser Symmans; Lajos Pusztai
Gene expression, molecular class changes, and pathway analysis after neoadjuvant systemic therapy for breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(4):1109-19.
2012: Susan L McGovern; Lajos Pusztai; Yuan Qi; William F Symmans; Thomas A Buchholz
Centromere protein-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer.
Breast cancer research : BCR 2012;14(3):R72.
2011: Lajos Pusztai
Anatomy and biology: two complementary sides of breast cancer prognostication.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(33):4347-8.
2011: Takayuki Iwamoto; Sang Bae Kim; Ju Seog Lee; Junji Matsuoka; Giampaolo Bianchini; Gabriel N Hortobagyi; Rebekah E Hubbard; W Fraser Symmans; Elliana Young; Lajos Pusztai
First generation prognostic gene signatures for breast cancer predict both survival and chemotherapy sensitivity and identify overlapping patient populations.
Breast cancer research and treatment 2011;130(1):155-64.
2011: Banu Arun; Deann Atchley; Soley Bayraktar; Angelica M Gutierrez Barrera; Gabriel N Hortobagyi; Jennifer Keating Litton; Diane D Liu; Funda Meric-Bernstam; Lajos Pusztai; Vicente Valero; Constance T Albarracin
Response to neoadjuvant systemic therapy for breast cancer in BRCA mutation carriers and noncarriers: a single-institution experience.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(28):3739-46.
2011: Antonio Giordano; Mario Giuliano; Kenneth Hess; Gabriel N Hortobagyi; Francesco Iorio; Lajos Pusztai; Massimo Cristofanilli; Michelino De Laurentiis; Sabino De Placido; Antonio Eleuteri; Roberto Tagliaferri; James M Reuben
Artificial neural network analysis of circulating tumor cells in metastatic breast cancer patients.
Breast cancer research and treatment 2011;129(2):451-8.
2011: Christine Desmedt; Angelo Di Leo; Evandro de Azambuja; Denis Larsimont; Benjamin Haibe-Kains; Jean Selleslags; Suzette Delaloge; Caroline Duhem; Jean-Pierre Kains; Birgit Carly; Marie Maerevoet; Anita Vindevoghel; Ghizlane Rouas; Françoise Lallemand; Virginie Durbecq; Fatima Cardoso; Roberto Salgado; Rodrigo Rovere; Gianluca Bontempi; Stefan Michiels; Marc Buyse; Jean-Marie Nogaret; Yuan Qi; Fraser Symmans; Lajos Pusztai; Véronique D'Hondt; Martine J Piccart-Gebhart; C Sotiriou
Multifactorial approach to predicting resistance to anthracyclines.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(12):1578-86.
2011: Charles Coutant; Roman Rouzier; Yuan Qi; Jacqueline Lehmann-Che; Giampaolo Bianchini; Takayuki Iwamoto; Gabriel N Hortobagyi; W Fraser Symmans; Serge Uzan; Fabrice Andre; Hugues de Thé; Lajos Pusztai
Distinct p53 gene signatures are needed to predict prognosis and response to chemotherapy in ER-positive and ER-negative breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(8):2591-601.
2011: Abigail S Caudle; Ana M Gonzalez-Angulo; Kelly K Hunt; Lajos Pusztai; Henry M Kuerer; Elizabeth A Mittendorf; Gabriel N Hortobagyi; Funda Meric-Bernstam
Impact of progression during neoadjuvant chemotherapy on surgical management of breast cancer.
Annals of surgical oncology 2011;18(4):932-8.
2011: Yun Gong; Eric Yulong Han; Ming Guo; Lajos Pusztai; Nour Sneige
Stability of estrogen receptor status in breast carcinoma: a comparison between primary and metastatic tumors with regard to disease course and intervening systemic therapy.
Cancer 2011;117(4):705-13.
2011: Takayuki Iwamoto; Giampaolo Bianchini; Daniel J Booser; Yuan Qi; Charles Coutant; Christine Ya-Hui Shiang; Libero Santarpia; Junji Matsuoka; Gabriel N Hortobagyi; W Fraser Symmans; Frankie A Holmes; Joyce A O'Shaughnessy; Beth Hellerstedt; John Pippen; Fabrice Andre; Richard Simon; Lajos Pusztai
Gene pathways associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer.
Journal of the National Cancer Institute 2011;103(3):264-72.
2011: Takayuki Iwamoto; Giampaolo Bianchini; Yuan Qi; Massimo Cristofanilli; Anthony Lucci; Wendy A Woodward; James M Reuben; Junji Matsuoka; Yun Gong; Savitri Krishnamurthy; Vicente Valero; Gabriel N Hortobagyi; Fredika Robertson; W Fraser Symmans; Lajos Pusztai; Naoto T Ueno
Different gene expressions are associated with the different molecular subtypes of inflammatory breast cancer.
Breast cancer research and treatment 2011;125(3):785-95.
2011: Lajos Pusztai; Takayuki Iwamoto
Breast cancer prognostic markers in the post-genomic era.
Breast cancer research and treatment 2011;125(3):647-50.
2011: Borbala Szekely; Lajos Pusztai
The value of genomic analysis of breast cancer in drug development.
Journal of the National Cancer Institute. Monographs 2011;2011(43):60-2.
2011: Ana M Gonzalez-Angulo; Bryan T Hennessy; Gabriel N Hortobagyi; Zhenlin Ju; Wenbin Liu; Ana Lluch; Funda Meric-Bernstam; Jan Alsner; Sam Aparicio; Anne-Lise Borresen-Dale; Russell Broaddus; Powel Brown; Mark S Carey; Kevin R Coombes; Lei Deng; Simen Myhre; Jens Overgaard; Lajos Pusztai; Aysegul Sahin; Corey Speers; W Fraser Symmans; Gordon B Mills
Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer.
Clinical proteomics 2011;8(1):11.
2010: Catherine M Kelly; Savitri Krishnamurthy; Giampaolo Bianchini; Jennifer K Litton; Ana M Gonzalez-Angulo; Gabriel N Hortobagyi; Lajos Pusztai
Utility of oncotype DX risk estimates in clinically intermediate risk hormone receptor-positive, HER2-normal, grade II, lymph node-negative breast cancers.
Cancer 2010;116(22):5161-7.
2010: Shivani S Shinde; Michele R Forman; Henry M Kuerer; Kai Yan; Florentia Peintinger; Kelly K Hunt; Gabriel N Hortobagyi; Lajos Pusztai; W Fraser Symmans
Higher parity and shorter breastfeeding duration: association with triple-negative phenotype of breast cancer.
Cancer 2010;116(21):4933-43.
2010: Giampaolo Bianchini; Yuan Qi; Ricardo H Alvarez; Takayuki Iwamoto; Charles Coutant; Nuhad K Ibrahim; Vicente Valero; Massimo Cristofanilli; Marjorie C Green; Laszlo Radvanyi; Christos Hatzis; Gabriel N Hortobagyi; Fabrice Andre; Luca Gianni; W Fraser Symmans; Lajos Pusztai
Molecular anatomy of breast cancer stroma and its prognostic value in estrogen receptor-positive and -negative cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(28):4316-23.
2010: Christine Y Shiang; Yuan Qi; Bailiang Wang; Vladimir Lazar; Jing Wang; W Fraser Symmans; Gabriel N Hortobagyi; Fabrice Andre; Lajos Pusztai
Amplification of fibroblast growth factor receptor-1 in breast cancer and the effects of brivanib alaninate.
Breast cancer research and treatment 2010;123(3):747-55.
2010: W Fraser Symmans; Christos Hatzis; Christos Sotiriou; Fabrice Andre; Florentia Peintinger; Peter Regitnig; Guenter Daxenbichler; Christine Desmedt; Julien Domont; Christian Marth; Suzette Delaloge; Thomas Bauernhofer; Vicente Valero; Daniel J Booser; Gabriel N Hortobagyi; Lajos Pusztai
Genomic index of sensitivity to endocrine therapy for breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(27):4111-9.
2010: Lara Lacerda; Lajos Pusztai; Wendy A Woodward
The role of tumor initiating cells in drug resistance of breast cancer: Implications for future therapeutic approaches.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2010;13(4-5):99-108.
2010: Cornelia Liedtke; Jing Wang; Attila Tordai; William F Symmans; Gabriel N Hortobagyi; Ludwig Kiesel; Kenneth Hess; Keith A Baggerly; Kevin R Coombes; Lajos Pusztai
Clinical evaluation of chemotherapy response predictors developed from breast cancer cell lines.
Breast cancer research and treatment 2010;121(2):301-9.
2010: Stacy Moulder; Kai Yan; Fei Huang; Kenneth R Hess; Cornelia Liedtke; Feng Lin; Christos Hatzis; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Development of candidate genomic markers to select breast cancer patients for dasatinib therapy.
Molecular cancer therapeutics 2010;9(5):1120-7.
2010: Olivier Graesslin; Bassam S Abdulkarim; Charles Coutant; Florence Huguet; Zsolt Gabos; Limin Hsu; Olivier Marpeau; Serge Uzan; Lajos Pusztai; Eric A Strom; Gabriel N Hortobagyi; Roman Rouzier; Nuhad K Ibrahim
Nomogram to predict subsequent brain metastasis in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(12):2032-7.
2010: Abigail S Caudle; Ana M Gonzalez-Angulo; Kelly K Hunt; Ping Liu; Lajos Pusztai; W Fraser Symmans; Henry M Kuerer; Elizabeth A Mittendorf; Gabriel N Hortobagyi; Funda Meric-Bernstam
Predictors of tumor progression during neoadjuvant chemotherapy in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(11):1821-8.
2010: Christine Shiang; Lajos Pusztai
Molecular profiling contributes more than routine histology and immonohistochemistry to breast cancer diagnostics.
Breast cancer research : BCR 2010;12 Suppl 4():S6.
2010: Lajos Pusztai; Giuseppe Viale; Catherine M Kelly; Clifford Hudis
Estrogen and HER-2 receptor discordance between primary breast cancer and metastasis.
The oncologist 2010;15(11):1164-8.
2010: Bradley M Broom; Waree Rinsurongkawong; Lajos Pusztai; Kim-Anh Do
Building networks with microarray data.
Methods in molecular biology (Clifton, N.J.) 2010;620():315-43.
2010: Fabrice Andre; Kristine Broglio; Lajos Pusztai; Narjiss Berrada; John R Mackey; Jean-Marc Nabholtz; Stephen Chan; Gabriel N Hortobagyi
Estrogen receptor expression and docetaxel efficacy in patients with metastatic breast cancer: a pooled analysis of four randomized trials.
The oncologist 2010;15(5):476-83.
2009: Fabrice Andre; Weiya Xia; R Conforti; Yongkun Wei; Thomas Boulet; Gorana Tomasic; Marc Spielmann; Moustafa Zoubir; Narjiss Berrada; Rodrigo Arriagada; Gabriel N Hortobagyi; Mien-Chie Hung; Lajos Pusztai; Suzette Delaloge; Stefan Michiels; Massimo Cristofanilli
CXCR4 expression in early breast cancer and risk of distant recurrence.
The oncologist 2009;14(12):1182-8.
2009: C Liedtke; Kristine Broglio; S Moulder; L Hsu; Shu-Wan Kau; W Fraser Symmans; Constance T Albarracin; Funda Meric-Bernstam; Wendy A Woodward; Richard L Theriault; L Kiesel; Gabriel N Hortobagyi; Lajos Pusztai; Ana M Gonzalez-Angulo
Prognostic impact of discordance between triple-receptor measurements in primary and recurrent breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(12):1953-8.
2009: Xiaohong Leng; Tian Ding; Hui Lin; Yan Wang; Limei Hu; Jianhua Hu; Barry Feig; Wei Zhang; Lajos Pusztai; W Fraser Symmans; Yun Wu; Ralph B Arlinghaus
Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis.
Cancer research 2009;69(22):8579-84.
2009: Lajos Pusztai; Jong-Hyeon Jeong; Yun Gong; Jeffrey S Ross; Chungyeul Kim; Soonmyung Paik; Roman Rouzier; Fabrice Andre; Gabriel N Hortobagyi; Norman Wolmark; W Fraser Symmans
Evaluation of microtubule-associated protein-Tau expression as a prognostic and predictive marker in the NSABP-B 28 randomized clinical trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(26):4287-92.
2009: Cornelia Liedtke; Christos Hatzis; W Fraser Symmans; Christine Desmedt; Benjamin Haibe-Kains; Vicente Valero; Henry M Kuerer; Gabriel N Hortobagyi; Martine Piccart-Gebhart; Christos Sotiriou; Lajos Pusztai
Genomic grade index is associated with response to chemotherapy in patients with breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(19):3185-91.
2009: Christos Sotiriou; Lajos Pusztai
Gene-expression signatures in breast cancer.
The New England journal of medicine 2009;360(8):790-800.
2009: Lajos Pusztai
Gene expression profiling of breast cancer.
Breast cancer research : BCR 2009;11 Suppl 3():S11.
2009: Jing Wang; Sijin Wen; W Fraser Symmans; Lajos Pusztai; Kevin R Coombes
The bimodality index: a criterion for discovering and ranking bimodal signatures from cancer gene expression profiling data.
Cancer informatics 2009;7():199-216.
2009: Attila Tordai; Cornelia Liedtke; Lajos Pusztai
Metastatic gene signatures and emerging novel prognostic tests in the management of early stage breast cancer.
Clinical & experimental metastasis 2009;26(7):625-32.
2008: Florentia Peintinger; Aman U Buzdar; Henry M Kuerer; Jaime A Mejia, M.D.; Christos Hatzis; Ana M Gonzalez-Angulo; Lajos Pusztai; Francisco J Esteva; S S Dawood; Marjorie C Green; Gabriel N Hortobagyi; W Fraser Symmans
Hormone receptor status and pathologic response of HER2-positive breast cancer treated with neoadjuvant chemotherapy and trastuzumab.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(12):2020-5.
2008: Lajos Pusztai; Kristine Broglio; Fabrice Andre; W Fraser Symmans; Kenneth R Hess; Gabriel N Hortobagyi
Effect of molecular disease subsets on disease-free survival in randomized adjuvant chemotherapy trials for estrogen receptor-positive breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(28):4679-83.
2008: Massimo Cristofanilli; Paolo Morandi; Savitri Krishnamurthy; James M Reuben; Bang-Ning Lee; Deborah Francis; Daniel J Booser; Marjorie C Green; B K Arun; Lajos Pusztai; Adriana Lopez; Rabiul Islam; Vicente Valero; Gabriel N Hortobagyi
Imatinib mesylate (Gleevec) in advanced breast cancer-expressing C-Kit or PDGFR-beta: clinical activity and biological correlations.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(10):1713-9.
2008: Lajos Pusztai
Preoperative systemic chemotherapy and pathologic assessment of response.
Pathology oncology research : POR 2008;14(2):169-71.
2008: Fabrice Andre; Kristine Broglio; Henri Roche; Miguel Martin; John R Mackey; Frederique Penault-Llorca; Gabriel N Hortobagyi; Lajos Pusztai
Estrogen receptor expression and efficacy of docetaxel-containing adjuvant chemotherapy in patients with node-positive breast cancer: results from a pooled analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(16):2636-43.
2008: Jeffrey S Ross; Christos Hatzis; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobágyi
Commercialized multigene predictors of clinical outcome for breast cancer.
The oncologist 2008;13(5):477-93.
2008: Lajos Pusztai
Current status of prognostic profiling in breast cancer.
The oncologist 2008;13(4):350-60.
2008: Florentia Peintinger; Henry M Kuerer; S E McGuire; Roland L Bassett; Lajos Pusztai; W Fraser Symmans
Residual specimen cellularity after neoadjuvant chemotherapy for breast cancer.
The British journal of surgery 2008;95(4):433-7.
2008: Cornelia Liedtke; Chafika Mazouni; Kenneth R Hess; Fabrice André; Attila Tordai; Jaime A Mejia, M.D.; W Fraser Symmans; Ana M Gonzalez-Angulo; Bryan T. J. Hennessy; Marjorie Green; Massimo Cristofanilli; Gabriel N Hortobagyi; Lajos Pusztai
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(8):1275-81.
2008: Fabrice Andre; Chafika Mazouni; Cornelia Liedtke; Shu-Wan Kau; Debby Frye; Marjorie Green; Ana M Gonzalez-Angulo; W Fraser Symmans; Gabriel N Hortobagyi; Lajos Pusztai
HER2 expression and efficacy of preoperative paclitaxel/FAC chemotherapy in breast cancer.
Breast cancer research and treatment 2008;108(2):183-90.
2008: Fabrice Andre; Rita Nahta; R Conforti; Thomas Boulet; M Aziz; Linda X H Yuan; Franck Meslin; Marc Spielmann; Gorana Tomasic; Lajos Pusztai; Gabriel N Hortobagyi; Stefan Michiels; Suzette Delaloge; Francisco J Esteva
Expression patterns and predictive value of phosphorylated AKT in early-stage breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(2):315-20.
2008: Attila Tordai; Jing Wang; Fabrice Andre; Cornelia Liedtke; Kai Yan; C Sotiriou; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Evaluation of biological pathways involved in chemotherapy response in breast cancer.
Breast cancer research : BCR 2008;10(2):R37.
2008: Cornelia Liedtke; Luca Cardone; Attila Tordai; Kai Yan; Henry L Gomez; Luis J Barajas Figureoa; Rebekah E Hubbard; Vicente Valero; Eduardo A Souchon; W Fraser Symmans; Gabriel N Hortobagyi; Alberto Bardelli; Lajos Pusztai
PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer.
Breast cancer research : BCR 2008;10(2):R27.
2007: Lajos Pusztai
Markers predicting clinical benefit in breast cancer from microtubule-targeting agents.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18 Suppl 12():xii15-20.
2007: Lajos Pusztai; Keith Anderson; Kenneth R Hess
Pharmacogenomic predictor discovery in phase II clinical trials for breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6080-6.
2007: Lajos Pusztai
Limitations of pharmacogenomic predictor discovery in Phase II clinical trials.
Pharmacogenomics 2007;8(10):1443-8.
2007: W Fraser Symmans; Florentia Peintinger; Christos Hatzis; Radhika Rajan; Henry M Kuerer; Vicente Valero; Lina Assad; Anna Poniecka; Bryan T. J. Hennessy; Marjorie Green; Aman U Buzdar; S Eva Singletary; Gabriel N Hortobagyi; Lajos Pusztai
Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(28):4414-22.
2007: Florentia Peintinger; Keith Anderson; Chafika Mazouni; Henry M Kuerer; Christos Hatzis; Feng Lin; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Thirty-gene pharmacogenomic test correlates with residual cancer burden after preoperative chemotherapy for breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(14):4078-82.
2007: Chafika Mazouni; Florentia Peintinger; Shu Wan-Kau; Fabrice Andre; Ana M Gonzalez-Angulo; W Fraser Symmans; Funda Meric-Bernstam; Vicente Valero; Gabriel N Hortobagyi; Lajos Pusztai
Residual ductal carcinoma in situ in patients with complete eradication of invasive breast cancer after neoadjuvant chemotherapy does not adversely affect patient outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(19):2650-5.
2007: Jeffrey S Ross; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobagyi
Standardizing slide-based assays in breast cancer: hormone receptors, HER2, and sentinel lymph nodes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(10):2831-5.
2007: Chafika Mazouni; Shu-Wan Kau; Debra Frye; Fabrice Andre; Henry M Kuerer; Thomas Buchholz; W Fraser Symmans; Keith Anderson; Kenneth R Hess; Ana M Gonzalez-Angulo; Gabriel N Hortobagyi; Aman U Buzdar; Lajos Pusztai
Inclusion of taxanes, particularly weekly paclitaxel, in preoperative chemotherapy improves pathologic complete response rate in estrogen receptor-positive breast cancers.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(5):874-80.
2007: Lajos Pusztai; Massimo Cristofanilli; Soonmyung Paik
New generation of molecular prognostic and predictive tests for breast cancer.
Seminars in oncology 2007;34(2 Suppl 3):S10-6.
2007: Fabrice Andre; Christos Hatzis; Keith Anderson; Christos Sotiriou; Chafika Mazouni; Jaime A Mejia, M.D.; Bailiang Wang; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Microtubule-associated protein-tau is a bifunctional predictor of endocrine sensitivity and chemotherapy resistance in estrogen receptor-positive breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2061-7.
2007: Lajos Pusztai
The use of microarray technology in the management of breast cancer.
Clinical advances in hematology & oncology : H&O 2007;5(3):193-4, 197.
2007: Yun Gong; Kai Yan; Feng Lin; Keith Anderson; Christos Sotiriou; Fabrice Andre; Frankie A Holmes; Vicente Valero; Daniel J Booser; John Pippen; Svetislava Vukelja; Henry Gomez; Jaime A Mejia, M.D.; Luis J Barajas; Kenneth R Hess; Nour Sneige; Gabriel N Hortobagyi; Lajos Pusztai; W Fraser Symmans
Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study.
The lancet oncology 2007;8(3):203-11.
2007: Chafika Mazouni; Angeline Hall; Kristine Broglio; Herbert A Fritsche; Fabrice Andre; Francisco J Esteva; Gabriel N Hortobagyi; Aman U Buzdar; Lajos Pusztai; Massimo Cristofanilli
Kinetics of serum HER-2/neu changes in patients with HER-2-positive primary breast cancer after initiation of primary chemotherapy.
Cancer 2007;109(3):496-501.
2007: Francisco J Esteva; Jing Wang; Feng Lin; Jaime A Mejia, M.D.; Kai Yan; Kadri Altundag; Vicente Valero; Aman U Buzdar; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer.
Breast cancer research : BCR 2007;9(6):R87.
2007: Aman U Buzdar; Vicente Valero; Nuhad K Ibrahim; Deborah Francis; Kristine Broglio; Richard L Theriault; Lajos Pusztai; Marjorie C Green; S Eva Singletary; Kelly K Hunt; Aysegul A Sahin; Francisco J Esteva; W Fraser Symmans; Michael S Ewer; Thomas Buchholz; Gabriel N Hortobagyi
Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomized study population and data of additional patients treated with the same regimen.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):228-33.
2006: Lajos Pusztai
Chips to bedside: incorporation of microarray data into clinical practice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7209-14.
2006: Fabrice Andre; Chafika Mazouni; Gabriel N Hortobagyi; Lajos Pusztai
DNA arrays as predictors of efficacy of adjuvant/neoadjuvant chemotherapy in breast cancer patients: current data and issues on study design.
Biochimica et biophysica acta 2006;1766(2):197-204.
2006: Fabrice Andre; Lajos Pusztai
Molecular classification of breast cancer: implications for selection of adjuvant chemotherapy.
Nature clinical practice. Oncology 2006;3(11):621-32.
2006: Roman Rouzier; Lajos Pusztai; Jean-Rémi Garbay; Suzette Delaloge; Kelly K Hunt; Gabriel N Hortobagyi; Donald Berry; Henry M Kuerer
Development and validation of nomograms for predicting residual tumor size and the probability of successful conservative surgery with neoadjuvant chemotherapy for breast cancer.
Cancer 2006;107(7):1459-66.
2006: Kenneth R Hess; Keith Anderson; W Fraser Symmans; Vicente Valero; Nuhad Ibrahim; Jaime A Mejia, M.D.; Daniel J Booser; Richard L Theriault; Aman U Buzdar; Peter J Dempsey; Roman Rouzier; Nour Sneige; Jeffrey S Ross; Tatiana Vidaurre; Henry L Gómez; Gabriel N Hortobagyi; Lajos Pusztai
Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(26):4236-44.
2006: Lajos Pusztai; Chafika Mazouni; Keith Anderson; Yun Wu; W Fraser Symmans
Molecular classification of breast cancer: limitations and potential.
The oncologist 2006;11(8):868-77.
2006: Judy C Boughey; Florentia Peintinger; Funda Meric-Bernstam; Allison C Perry; Kelly K Hunt; Gildy V Babiera; S E Singletary; Isabelle Bedrosian; Anthony Lucci; Aman U Buzdar; Lajos Pusztai; Henry M Kuerer
Impact of preoperative versus postoperative chemotherapy on the extent and number of surgical procedures in patients treated in randomized clinical trials for breast cancer.
Annals of surgery 2006;244(3):464-70.
2006: Fabrice Andre; Lajos Pusztai
Heterogeneity of breast cancer among patients and implications for patient selection for adjuvant chemotherapy.
Pharmaceutical research 2006;23(9):1951-8.
2006: C H Yang; Ana M Gonzalez-Angulo; James M Reuben; Daniel J Booser; Lajos Pusztai; Savitri Krishnamurthy; Dixie Esseltine; James Stec; Kristine Broglio; Rabiul Islam; Gabriel N Hortobagyi; Massimo Cristofanilli
Bortezomib (VELCADE) in metastatic breast cancer: pharmacodynamics, biological effects, and prediction of clinical benefits.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(5):813-7.
2006: Keith Anderson; Kenneth R Hess; Mini Kapoor; Stephen Tirrell; Jean Courtemanche; Bailiang Wang; Yun Wu; Yun Gong; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Reproducibility of gene expression signature-based predictions in replicate experiments.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1721-7.
2006: Lajos Pusztai; Francisco J Esteva
Continued use of trastuzumab (herceptin) after progression on prior trastuzumab therapy in HER-2-positive metastatic breast cancer.
Cancer investigation 2006;24(2):187-91.
2006: Lajos Pusztai
Development of pharmacogenomic predictors for preoperative chemotherapy of breast cancer.
Advances in experimental medicine and biology 2006;587():233-49.
2006: Yuan Ji; Kevin R Coombes; Jiexin Zhang; Sijin Wen; James Mitchell; Lajos Pusztai; W Fraser Symmans; Jing Wang
RefSeq refinements of UniGene-based gene matching improve the correlation of expression measurements between two microarray platforms.
Applied bioinformatics 2006;5(2):89-98.
2006: Linda J Adepoju; W Fraser Symmans; Gildy V Babiera; S Eva Singletary; Banu Arun; Nour Sneige; Lajos Pusztai; Thomas Buchholz; Aysegul Sahin; Kelly K Hunt; Funda Meric-Bernstam; Merrick I Ross; Frederick C Ames; Henry M Kuerer
Impact of concurrent proliferative high-risk lesions on the risk of ipsilateral breast carcinoma recurrence and contralateral breast carcinoma development in patients with ductal carcinoma in situ treated with breast-conserving therapy.
Cancer 2006;106(1):42-50.
2005: Jeffrey S Ross; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobagyi
Pharmacogenomics and clinical biomarkers in drug discovery and development.
American journal of clinical pathology 2005;124 Suppl():S29-41.
2005: W Fraser Symmans; Derek J Fiterman; S K Anderson; Mark Ayers; Roman Rouzier; Valerie Dunmire; James Stec; Vicente Valero; Nour Sneige; Constance T Albarracin; Yun Wu; Jeffrey S Ross; Peter Wagner; Richard L Theriault; Banu Arun; Henry M Kuerer; Kenneth R Hess; Wei Zhang; Gabriel N Hortobagyi; Lajos Pusztai
A single-gene biomarker identifies breast cancers associated with immature cell type and short duration of prior breastfeeding.
Endocrine-related cancer 2005;12(4):1059-69.
2005: Thomas Buchholz; Amit K Garg; Nitin Chakravarti; Bharat B Aggarwal; Francisco J Esteva; Henry M Kuerer; S Eva Singletary; Gabriel N Hortobagyi; Lajos Pusztai; Massimo Cristofanilli; Aysegul A Sahin
The nuclear transcription factor kappaB/bcl-2 pathway correlates with pathologic complete response to doxorubicin-based neoadjuvant chemotherapy in human breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(23):8398-402.
2005: Roman Rouzier; Lajos Pusztai; Suzette Delaloge; Ana M Gonzalez-Angulo; Fabrice Andre; Kenneth R Hess; Aman U Buzdar; Jean-Rémi Garbay; Marc Spielmann; Marie-Christine Mathieu; W Fraser Symmans; Peter Wagner; david atallah; Vicente Valero; Donald A Berry; Gabriel N Hortobagyi
Nomograms to predict pathologic complete response and metastasis-free survival after preoperative chemotherapy for breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(33):8331-9.
2005: Francisco J Esteva; Lajos Pusztai
Optimizing outcomes in HER2-positive breast cancer: the molecular rationale.
Oncology (Williston Park, N.Y.) 2005;19(13 Suppl 5):5-16.
2005: Marjorie C Green; Aman U Buzdar; Terry Smith; Nuhad K Ibrahim; Vicente Valero; Marguerite F Rosales; Massimo Cristofanilli; Daniel J Booser; Lajos Pusztai; Edgardo Rivera; Richard L Theriault; Cynthia Carter; Debra Frye; Kelly K Hunt; W Fraser Symmans; Eric A Strom; Aysegul A Sahin; William Sikov; Gabriel N Hortobagyi
Weekly paclitaxel improves pathologic complete remission in operable breast cancer when compared with paclitaxel once every 3 weeks.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(25):5983-92.
2005: Roman Rouzier; Charles M Perou; W Fraser Symmans; Nuhad Ibrahim; Massimo Cristofanilli; Keith Anderson; Kenneth R Hess; James Stec; Mark Ayers; Peter Wagner; Paolo Morandi; Chang Fan; Islam Rabiul; Jeffrey S Ross; Gabriel N Hortobagyi; Lajos Pusztai
Breast cancer molecular subtypes respond differently to preoperative chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):5678-85.
2005: Lajos Pusztai; Peter Wagner; Nuhad Ibrahim; Edgardo Rivera; Richard Theriault; Daniel J Booser; Fraser W Symmans; Franklin Wong; George R Blumenschein; Donald R Fleming; Roman Rouzier; Graeme Boniface; Gabriel N Hortobagyi
Phase II study of tariquidar, a selective P-glycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma.
Cancer 2005;104(4):682-91.
2005: Thomas Buchholz; Xiaoyu Tu; K. Kian Ang; Francisco J Esteva; Henry M Kuerer; Lajos Pusztai; Massimo Cristofanilli; S Eva Singletary; Gabriel N Hortobagyi; Aysegul A Sahin
Epidermal growth factor receptor expression correlates with poor survival in patients who have breast carcinoma treated with doxorubicin-based neoadjuvant chemotherapy.
Cancer 2005;104(4):676-81.
2005: James Stec; Jing Wang; Kevin R Coombes; Mark Ayers; Sebastian Hoersch; David L Gold; Jeffrey S Ross; Kenneth R Hess; Stephen Tirrell; Gerald P Linette; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Comparison of the predictive accuracy of DNA array-based multigene classifiers across cDNA arrays and Affymetrix GeneChips.
The Journal of molecular diagnostics : JMD 2005;7(3):357-67.
2005: Roman Rouzier; Radhika Rajan; Peter Wagner; Kenneth R Hess; David L Gold; James Stec; Mark Ayers; Jeffrey S Ross; Peter Zhang; Thomas Buchholz; Henry M Kuerer; Marjorie Green; Banu Arun; Gabriel N Hortobagyi; W Fraser Symmans; Lajos Pusztai
Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8315-20.
2005: Aman U Buzdar; Nuhad K Ibrahim; Deborah Francis; Daniel J Booser; Eva S Thomas; Richard L Theriault; Lajos Pusztai; Marjorie C Green; Banu Arun; Sharon H Giordano; Massimo Cristofanilli; Debra Frye; Terry L Smith; Kelly K Hunt; S Eva Singletary; Aysegul A Sahin; Michael S Ewer; Thomas Buchholz; Donald Berry; Gabriel N Hortobagyi
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(16):3676-85.
2005: Jeffrey S Ross; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobagyi
Breast cancer biomarkers.
Advances in clinical chemistry 2005;40():99-125.
2005: Lajos Pusztai; Fraser W Symmans; Gabriel N Hortobagyi
Development of pharmacogenomic markers to select preoperative chemotherapy for breast cancer.
Breast cancer (Tokyo, Japan) 2005;12(2):73-85.
2005: Timothy M Pawlik; Herbert A Fritsche; Kevin R Coombes; Lianchun Xiao; Savitri Krishnamurthy; Kelly K Hunt; Lajos Pusztai; Jeng-Neng Chen; Charlotte H Clarke; Banu Arun; Mien-Chie Hung; Henry M Kuerer
Significant differences in nipple aspirate fluid protein expression between healthy women and those with breast cancer demonstrated by time-of-flight mass spectrometry.
Breast cancer research and treatment 2005;89(2):149-57.
2005: Roman Rouzier; Peter Wagner; Paolo Morandi; Lajos Pusztai
Gene expression profiling of primary breast cancer.
Current oncology reports 2005;7(1):38-44.
2004: Lajos Pusztai; Roman Rouzier; Peter Wagner; W Fraser Symmans
Individualized chemotherapy treatment for breast cancer: is it necessary? Is it feasible?
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2004;7(6):325-31.
2004: Lajos Pusztai; Kenneth R Hess
Clinical trial design for microarray predictive marker discovery and assessment.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(12):1731-7.
2004: Lajos Pusztai; Luca Gianni
Technology insight: Emerging techniques to predict response to preoperative chemotherapy in breast cancer.
Nature clinical practice. Oncology 2004;1(1):44-50.
2004: B Wang; Roman Rouzier; Constance T Albarracin; Aysegul Sahin; Peter Wagner; Y Yang; T L Smith; F Meric-Bernstam; C Marcelo Aldaz; A C Marcelo; Gabriel N Hortobagyi; Lajos Pusztai
Expression of sigma 1 receptor in human breast cancer.
Breast cancer research and treatment 2004;87(3):205-14.
2004: Jeffrey S Ross; David P Schenkein; Robert Pietrusko; Mark Rolfe; Gerald P Linette; James Stec; Nancy Stagliano; Geoffrey S Ginsburg; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobagyi
Targeted therapies for cancer 2004.
American journal of clinical pathology 2004;122(4):598-609.
2004: Thomas Buchholz; Eugene H Huang; Donald Berry; Lajos Pusztai; Eric A Strom; Marsha D McNeese; George H Perkins; Naomi R Schechter; Henry M Kuerer; Aman U Buzdar; Vicente Valero; Kelly K Hunt; Gabriel N Hortobagyi; Aysegul A Sahin
Her2/neu-positive disease does not increase risk of locoregional recurrence for patients treated with neoadjuvant doxorubicin-based chemotherapy, mastectomy, and radiotherapy.
International journal of radiation oncology, biology, physics 2004;59(5):1337-42.
2004: Ana M Gonzalez-Angulo; Savitri Krishnamurthy; Yuko Yamamura; Kristine Broglio; Lajos Pusztai; Aman U Buzdar; Gabriel N Hortobagyi; Francisco J Esteva
Lack of association between amplification of her-2 and response to preoperative taxanes in patients with breast carcinoma.
Cancer 2004;101(2):258-63.
2004: Jeffrey S Ross; David P Schenkein; Oscar Kashala; Gerald P Linette; James Stec; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobagyi
Pharmacogenomics.
Advances in anatomic pathology 2004;11(4):211-20.
2004: Mark Ayers; W Fraser Symmans; James Stec; Andrew I Damokosh; E Clark; K Hess; M Lecocke; J Metivier; Daniel J Booser; Nuhad Ibrahim; Vicente Valero; Melanie Royce; Banu Arun; G Whitman; J Ross; Nour Sneige; Gabriel N Hortobagyi; Lajos Pusztai
Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(12):2284-93.
2004: Lajos Pusztai; Betsy Gregory; Keith A Baggerly; Bo Peng; John M Koomen; Henry M Kuerer; Francisco J Esteva; W Fraser Symmans; Peter Wagner; Gabriel N Hortobagyi; Christine Laronga; O John Semmes; George L Wright; Richard R Drake; Antonia Vlahou
Pharmacoproteomic analysis of prechemotherapy and postchemotherapy plasma samples from patients receiving neoadjuvant or adjuvant chemotherapy for breast carcinoma.
Cancer 2004;100(9):1814-22.
2004: Radhika Rajan; Anna Poniecka; Terry L Smith; Ying Yang; Deborah Frye; Lajos Pusztai; Derek J Fiterman; Eva Gal-Gombos; Gary J Whitman; Roman Rouzier; Marjorie Green; Henry M Kuerer; Aman U Buzdar; Gabriel N Hortobagyi; W Fraser Symmans
Change in tumor cellularity of breast carcinoma after neoadjuvant chemotherapy as a variable in the pathologic assessment of response.
Cancer 2004;100(7):1365-73.
2004: Jeffrey S Ross; Jonathan A Fletcher; Kenneth J Bloom; Gerald P Linette; James Stec; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobagyi
Targeted therapy in breast cancer: the HER-2/neu gene and protein.
Molecular & cellular proteomics : MCP 2004;3(4):379-98.
2004: Jeffrey S Ross; Gerald P Linette; James Stec; Edward Clark; Mark Ayers; Nick Leschly; W Fraser Symmans; Gabriel N Hortobagyi; Lajos Pusztai
Breast cancer biomarkers and molecular medicine: part II.
Expert review of molecular diagnostics 2004;4(2):169-88.
2004: Lajos Pusztai; Tito R Mendoza; James M Reuben; Monica M Martinez; Jie S Willey; Juanita Lara; Abdul Syed; Herbert A Fritsche; Eduardo Bruera; Daniel J Booser; Vicente Valero; Banu Arun; Nuhad Ibrahim; Edgardo Rivera; Melanie Royce; Charles S Cleeland; Gabriel N Hortobagyi
Changes in plasma levels of inflammatory cytokines in response to paclitaxel chemotherapy.
Cytokine 2004;25(3):94-102.
2004: Francisco J Esteva; Aysegul A Sahin; Terry L Smith; Ying Yang; Lajos Pusztai; Rita Nahta; Thomas Buchholz; Aman U Buzdar; Gabriel N Hortobagyi; Sarah S Bacus
Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma.
Cancer 2004;100(3):499-506.
2004: Lajos Pusztai; Savitri Krishnamurti; Jorge Perez Cardona; Nour Sneige; Francisco J Esteva; Marina Volchenok; Patricia Breitenfelder; Shu-Wan Kau; Shin Takayama; Stanislaw Krajewski; John C Reed; Robert C Bast; Gabriel N Hortobagyi
Expression of BAG-1 and BcL-2 proteins before and after neoadjuvant chemotherapy of locally advanced breast cancer.
Cancer investigation 2004;22(2):248-56.
2003: Jeffrey S Ross; Jonathan A Fletcher; Kenneth J Bloom; Gerald P Linette; James Stec; Edward Clark; Mark Ayers; W Fraser Symmans; Lajos Pusztai; Gabriel N Hortobagyi
HER-2/neu testing in breast cancer.
American journal of clinical pathology 2003;120 Suppl():S53-71.
2003: Francisco J Esteva; Aysegul A Sahin; George Z Rassidakis; Linda X H Yuan; Terry L Smith; Ying Yang; Michael Z Gilcrease; Massimo Cristofanilli; Rita Nahta; Lajos Pusztai; Francois Claret
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5652-9.
2003: Lajos Pusztai; Jim Hou Zhen; Banu Arun; Edgardo Rivera; Clark Whitehead; W Joseph Thompson; Kimberly M Nealy; Amy Gibbs; W Fraser Symmans; Francisco J Esteva; Daniel J Booser; James L Murray; Vicente Valero; Terry L Smith; Gabriel N Hortobagyi
Phase I and II study of exisulind in combination with capecitabine in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(18):3454-61.
2003: Jeffrey S Ross; Gerald P Linette; James Stec; Edward Clark; Mark Ayers; Nick Leschly; W Fraser Symmans; Gabriel N Hortobagyi; Lajos Pusztai
Breast cancer biomarkers and molecular medicine.
Expert review of molecular diagnostics 2003;3(5):573-85.
2003: Edgardo Rivera; Vicente Valero; Banu Arun; Melanie Royce; Rosnie B Adinin; Karen Hoelzer; Ronald Walters; James L Wade Iii; Lajos Pusztai; Gabriel N Hortobagyi
Phase II study of pegylated liposomal doxorubicin in combination with gemcitabine in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(17):3249-54.
2003: Lajos Pusztai; Mark Ayers; James Stec; Edward Clark; Kenneth Hess; David N Stivers; Andrew I Damokosh; Nour Sneige; Thomas Buchholz; Francisco J Esteva; Banu Arun; Massimo Cristofanilli; Daniel J Booser; Marguerite Rosales; Vicente Valero; Constantine Adams; Gabriel N Hortobagyi; W Fraser Symmans
Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2406-15.
2003: W Fraser Symmans; Mark Ayers; Edwin A Clark; James Stec; Kenneth R Hess; Nour Sneige; Thomas Buchholz; Savitri Krishnamurthy; Nuhad K Ibrahim; Aman U Buzdar; Richard L Theriault; Marguerite F Rosales; Eva S Thomas; Karin Gwyn; Marjorie C Green; Abdul R Syed; Gabriel N Hortobagyi; Lajos Pusztai
Total RNA yield and microarray gene expression profiles from fine-needle aspiration biopsy and core-needle biopsy samples of breast carcinoma.
Cancer 2003;97(12):2960-71.
2003: Fan Zhang; Ying Yang; Terry Smith; Shu-Wan Kau; Judy M McConathy; Francisco J Esteva; Henry M Kuerer; W Fraser Symmans; Aman U Buzdar; Gabriel N Hortobagyi; Lajos Pusztai
Correlation between HER-2 expression and response to neoadjuvant chemotherapy with 5-fluorouracil, doxorubicin, and cyclophosphamide in patients with breast carcinoma.
Cancer 2003;97(7):1758-65.
2003: Kenneth R Hess; Lajos Pusztai; Aman U Buzdar; Gabriel N Hortobagyi
Estrogen receptors and distinct patterns of breast cancer relapse.
Breast cancer research and treatment 2003;78(1):105-18.
2003: Lajos Pusztai; Christos Sotiriou; Thomas Buchholz; Funda Meric; W Fraser Symmans; Francisco J Esteva; Aysegul Sahin; Edison Liu; Gabriel N Hortobagi
Molecular profiles of invasive mucinous and ductal carcinomas of the breast: a molecular case study.
Cancer genetics and cytogenetics 2003;141(2):148-53.
2003: Jeffrey S Ross; Jonathan A Fletcher; Gerald P Linette; James Stec; Edward Clark; Mark Ayers; W Fraser Symmans; Lajos Pusztai; Kenneth J Bloom
The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy.
The oncologist 2003;8(4):307-25.
2003: Lajos Pusztai; Mark Ayers; James Stec; Gabriel N Hortobágyi
Clinical application of cDNA microarrays in oncology.
The oncologist 2003;8(3):252-8.
2003: Thomas Buchholz; Darren W Davis; David J McConkey; W Fraser Symmans; Vicente Valero; Anuja Jhingran; Susan L Tucker; Lajos Pusztai; Massimo Cristofanilli; Francisco J Esteva; Gabriel N Hortobagyi; Aysegul A Sahin
Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy.
Cancer journal (Sudbury, Mass.) 2003;9(1):33-41.
2002: Thomas Buchholz; David N Stivers; James Stec; Mark Ayers; Edward Clark; Bolt Andrew; Aysegul A Sahin; W Fraser Symmans; Kenneth R Hess; Henry M Kuerer; Vicente Valero; Gabriel N Hortobagyi; Lajos Pusztai
Global gene expression changes during neoadjuvant chemotherapy for human breast cancer.
Cancer journal (Sudbury, Mass.) 2002;8(6):461-8.
2002: Francisco J Esteva; Vicente Valero; Daniel J Booser; Laura T Guerra; James L Murray; Lajos Pusztai; Massimo Cristofanilli; Banu Arun; Bita Esmaeli; Herbert A Fritsche; Nour Sneige; Terry L Smith; Gabriel N Hortobagyi
Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(7):1800-8.
2001: Thomas Buchholz; B S Hill; Susan L Tucker; Debra Frye; Henry M Kuerer; A U Buzdar; M D McNeese; S Eva Singletary; Naoto T Ueno; Lajos Pusztai; Vicente Valero; Gabriel N Hortobagyi
Factors predictive of outcome in patients with breast cancer refractory to neoadjuvant chemotherapy.
Cancer journal (Sudbury, Mass.) 2001;7(5):413-20.
2001: Francisco J Esteva; G N Hortobagyi; Aysegul A Sahin; T L Smith; Dot Mon Chin; S Y Liang; Lajos Pusztai; A U Buzdar; Sarah S Bacus
Expression of erbB/HER receptors, heregulin and P38 in primary breast cancer using quantitative immunohistochemistry.
Pathology oncology research : POR 2001;7(3):171-7.
2001: Francisco J Esteva; V Valero; Lajos Pusztai; L Boehnke-Michaud; Aman U Buzdar; G N Hortobagyi
Chemotherapy of metastatic breast cancer: what to expect in 2001 and beyond.
The oncologist 2001;6(2):133-46.
2000: Timothy Madden; Hai T Tran; D Beck; R Huie; Robert A Newman; Lajos Pusztai; J J Wright; James L Abbruzzese
Novel marine-derived anticancer agents: a phase I clinical, pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1293-301.
1999: Lajos Pusztai; F J Esteva; M Cristofanilli; Mien-Chie Hung; Gabriel N Hortobagyi
Chemo-signal therapy, an emerging new approach to modify drug resistance in breast cancer.
Cancer treatment reviews 1999;25(5):271-7.
1999: Lajos Pusztai; Lina Asmar; T L Smith; Gabriel N Hortobagyi
Relapse after complete response to anthracycline-based combination chemotherapy in metastatic breast cancer.
Breast cancer research and treatment 1999;55(1):1-8.
1998: Lajos Pusztai; G N Hortobagyi
High-dose chemotherapy: how resistant is breast cancer?
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 1998;1(1):62-72.