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Wenbo Qi

Research Profile

Disorders

Chemicals & Drugs

Physiology

Lipid Peroxidation

Living Beings

Anatomy

Livers

Phenomena

Oxidation-Reduction

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Publications

TOP 3
Yiqiang Zhang; Hong-Mei Zhang; Alex Bokov; Jonathan Gelfond; Gene Hubbard; Yuji Ikeno; Carlos Jaramillo; Yuhong Liu; Wenbo Qi; Arlan Richardson; Holly Van Remmen
Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice.
Yun Shi; Lauren B Sloane; Zoltan Ungvari; Steven Austad; Arunabh Bhattacharya; Rochelle Buffenstein; Asish Chaudhuri; Ryan T Hamilton; Amanda L Jernigan; Yuhong Liu; Daniel A Pulliam; Wenbo Qi; Holly Van Remmen
Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.
Young C Jang; Yan Li; Yuhong Liu; Michael S Lustgarten; Florian L Muller; Wenbo Qi; Arlan G Richardson; Arunabh Bhattacharya; Asish Chaudhuri; Christopher R Hayworth; Jing-Yi Huang; Eric Verdin; Holly Van Remmen
Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.

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All Publications

2013: Yiqiang Zhang; Hong-Mei Zhang; Alex Bokov; Jonathan Gelfond; Gene Hubbard; Yuji Ikeno; Carlos Jaramillo; Yuhong Liu; Wenbo Qi; Arlan Richardson; Holly Van Remmen
Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice.
Free radical biology & medicine 2013;60():300-6.
2013: Yun Shi; Lauren B Sloane; Zoltan Ungvari; Steven Austad; Arunabh Bhattacharya; Rochelle Buffenstein; Asish Chaudhuri; Ryan T Hamilton; Amanda L Jernigan; Yuhong Liu; Daniel A Pulliam; Wenbo Qi; Holly Van Remmen
Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.
American journal of physiology. Regulatory, integrative and comparative physiology 2013;304(5):R343-55.
2012: Young C Jang; Yan Li; Yuhong Liu; Michael S Lustgarten; Florian L Muller; Wenbo Qi; Arlan G Richardson; Arunabh Bhattacharya; Asish Chaudhuri; Christopher R Hayworth; Jing-Yi Huang; Eric Verdin; Holly Van Remmen
Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.
Aging cell 2012;11(5):770-82.
2011: Viviana I Pérez; Wenbo Qi; Arlan G Richardson; Marisela Rodriguez; Kaoru Tominaga; Holly Van Remmen; Celeste R Webb; Junji Yodoi; Yiqiang Zhang; Alex Bokov; Asish Chaudhuri; Lisa A Cortez; Wilson Fok; Gene B Hubbard; Dean P Jones; Shuko Lee; Christie M Lew; Yuji Ikeno
Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.
The journals of gerontology. Series A, Biological sciences and medical sciences 2011;66(12):1286-99.
2011: Michael S Lustgarten; Florian L Muller; Wenbo Qi; Yuejuan Qin; Arlan G Richardson; Yun Shi; Takahiko Shimizu; Takuji Shirasawa; Arunabh Bhattacharya; Patricia Dahia; Youngmok C Jang; Yuhong Liu; Holly Van Remmen
MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging.
Aging cell 2011;10(3):493-505.
2010: Yiqiang Zhang; Hong-Mei Zhang; Yun Shi; Michael Lustgarten; Yan Li; Wenbo Qi; Bin-Xian Zhang; Holly Van Remmen
Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts.
Free radical biology & medicine 2010;49(8):1255-62.
2009: Yiqiang Zhang; Yuji Ikeno; Wenbo Qi; Asish Chaudhuri; Yan Li; Alex Bokov; Suzanne R Thorpe; John W Baynes; Charles Epstein; Arlan G Richardson; Holly Van Remmen
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences 2009;64(12):1212-20.
2009: Youngmok C Jang; Viviana Perez; Wook Song; Michael S Lustgarten; Adam B Salmon; James Mele; Wenbo Qi; Yuhong Liu; Hanyu Liang; Asish Chaudhuri; Yuji Ikeno; Charles J Epstein; Holly Van Remmen; Arlan G Richardson
Overexpression of Mn superoxide dismutase does not increase life span in mice.
The journals of gerontology. Series A, Biological sciences and medical sciences 2009;64(11):1114-25.
2008: Liuji Chen; Ren Na; Mingjun Gu; Adam B Salmon; Yuhong Liu; Hanyu Liang; Wenbo Qi; Holly Van Remmen; Arlan G Richardson; Qitao Ran
Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice.
Aging cell 2008;7(6):866-78.
2008: Viviana Perez; Christie M Lew; Lisa A Cortez; Celeste R Webb; Marisela Rodriguez; Yuhong Liu; Wenbo Qi; Yan Li; Asish Chaudhuri; Holly Van Remmen; Arlan G Richardson; Yuji Ikeno
Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress.
Free radical biology & medicine 2008;44(5):882-92.
2007: Qitao Ran; Hanyu Liang; Yuji Ikeno; Wenbo Qi; Tomas A Prolla; L Jackson Roberts; Norman Wolf; Holly Van Remmen; Holly VanRemmen; Arlan G Richardson
Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(9):932-42.
2005: Walter F Ward; Wenbo Qi; Holly Van Remmen; William E Zackert; L Jackson Roberts; Arlan G Richardson
Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels.
The journals of gerontology. Series A, Biological sciences and medical sciences 2005;60(7):847-51.
2004: Qitao Ran; Hanyu Liang; Minjun Gu; Wenbo Qi; Christi A Walter; L Jackson Roberts; Brian Herman; Arlan G Richardson; Holly Van Remmen
Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis.
The Journal of biological chemistry 2004;279(53):55137-46.
2004: Holly Van Remmen; Wenbo Qi; Marian Sabia; Gregory Freeman; Larry Estlack; Hong Yang; Zhong Mao Guo; Ting-Ting Huang; John Strong; Shuko Lee; Charles J Epstein; Arlan G Richardson
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress.
Free radical biology & medicine 2004;36(12):1625-34.
2003: Qitao Ran; Holly Van Remmen; Mingjun Gu; Wenbo Qi; L Jackson Roberts; Tomas A Prolla; Arlan G Richardson
Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes.
Free radical biology & medicine 2003;35(9):1101-9.
2001: Wenbo Qi; Russel J Reiter; Dun-Xian Tan; Lucien C Manchester; Juan R Calvo
Melatonin prevents delta-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+.
Molecular and cellular biochemistry 2001;218(1-2):87-92.
2000: Dun-Xian Tan; Lucien C Manchester; Russel J Reiter; Benjamin F Plummer; J Limson; Susan Weintraub; Wenbo Qi
Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation.
Free radical biology & medicine 2000;29(11):1177-85.
2000: Malgorzata Karbownik; Russel J Reiter; JJ Garcia; Dun-Xian Tan; Wenbo Qi; Lucien C Manchester
Melatonin reduces rat hepatic macromolecular damage due to oxidative stress caused by delta-aminolevulinic acid.
Biochimica et biophysica acta 2000;1523(2-3):140-6.
2000: Malgorzata Karbownik; Russel J Reiter; Wenbo Qi; JJ Garcia; Dun-Xian Tan; Lucien C Manchester
Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation.
Molecular and cellular biochemistry 2000;211(1-2):137-44.
2000: Wenbo Qi; Russel J Reiter; Dun-Xian Tan; Lucien C Manchester; Andrew W Siu; JJ Garcia
Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules.
Journal of pineal research 2000;29(1):54-61.
2000: Rosa M Sainz; Russel J Reiter; Juan Mayo; J Cabrera; Dun-Xian Tan; Wenbo Qi; JJ Garcia
Changes in lipid peroxidation during pregnancy and after delivery in rats: effect of pinealectomy.
Journal of reproduction and fertility 2000;119(1):143-9.
2000: Wenbo Qi; Russel J Reiter; Dun-Xian Tan; JJ Garcia; Lucien C Manchester; Malgorzata Karbownik; Juan R Calvo
Chromium(III)-induced 8-hydroxydeoxyguanosine in DNA and its reduction by antioxidants: comparative effects of melatonin, ascorbate, and vitamin E.
Environmental health perspectives 2000;108(5):399-402.
2000: J Cabrera; Russel J Reiter; Dun-Xian Tan; Wenbo Qi; Rosa M Sainz; Juan Mayo; JJ Garcia; S J Kim; Gamal H El-Sokkary
Melatonin reduces oxidative neurotoxicity due to quinolinic acid: in vitro and in vivo findings.
Neuropharmacology 2000;39(3):507-14.
2000: Joaquín J García; Russel J Reiter; J J Cabrera; J Pié; Juan Mayo; Rosa M Sáinz; Dun-Xian Tan; Wenbo Qi; Darío Acuña-Castroviejo
5-methoxytryptophol preserves hepatic microsomal membrane fluidity during oxidative stress.
Journal of cellular biochemistry 2000;76(4):651-7.
1999: Wenbo Qi; Russel J Reiter; Dun-Xian Tan; Lucien C Manchester; S J Kim; JJ Garcia
Inhibitory effects of melatonin on ferric nitrilotriacetate-induced lipid peroxidation and oxidative DNA damage in the rat kidney.
Toxicology 1999;139(1-2):81-91.
1999: Wenbo Qi; Dun-Xian Tan; Russel J Reiter; S J Kim; Lucien C Manchester; J Cabrera; Rosa M Sainz; Juan Mayo
Melatonin reduces lipid peroxidation and tissue edema in cerulein-induced acute pancreatitis in rats.
Digestive diseases and sciences 1999;44(11):2257-62.
1999: Russel J Reiter; D Tan; S J Kim; Lucien C Manchester; Wenbo Qi; JJ Garcia; J C Cabrera; Gamal H El-Sokkary; V Rouvier-Garay
Augmentation of indices of oxidative damage in life-long melatonin-deficient rats.
Mechanisms of ageing and development 1999;110(3):157-73.
1998: Dun-Xian Tan; Lucien C Manchester; Russel J Reiter; Wenbo Qi; S J Kim; Gamal H El-Sokkary
Melatonin protects hippocampal neurons in vivo against kainic acid-induced damage in mice.
Journal of neuroscience research 1998;54(3):382-9.
1998: Dun-Xian Tan; Lucien C Manchester; Russel J Reiter; Wenbo Qi; S J Kim; Gamal H El-Sokkary
Ischemia/reperfusion-induced arrhythmias in the isolated rat heart: prevention by melatonin.
Journal of pineal research 1998;25(3):184-91.
1998: S J Kim; Russel J Reiter; M V Rouvier Garay; Wenbo Qi; Gamal H El-Sokkary; Dun-Xian Tan
2-Nitropropane-induced lipid peroxidation: antitoxic effects of melatonin.
Toxicology 1998;130(2-3):183-90.
1998: Russel J Reiter; Dun-Xian Tan; S J Kim; Wenbo Qi
Melatonin as a pharmacological agent against oxidative damage to lipids and DNA.
Proceedings of the Western Pharmacology Society 1998;41():229-36.