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Wen Qian

Research Profile

Physiology

Signal Transduction

Chemicals & Drugs

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Publications

TOP 3
Jarod A Zepp; Muhammet Fatih Gulen; Zizhen Kang; Caini Liu; Wen Qian; Ling Wu; Xiaoxia Li
Cutting edge: TNF receptor-associated factor 4 restricts IL-17-mediated pathology and signaling processes.
Katarzyna Bulek; Muhammet Fatih Gulen; Thomas Hamilton; Vincent Hascall; Tomasz Herjan; Mark Lauer; Amina Abbadi; Mark A Aronica; Caini Liu; Saurav Misra; Richard C Page; Wen Qian; Dongxu Sun; Shadi Swaidani; Liwen Wang; Mark R Chance; Xiaoxia Li
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation.
Caini Liu; Saurav Misra; Wen Qian; Paige Sun; Shadi Swaidani; Chenhui Wang; Weiguo Yin; Chunjiang Zhang; Mark A Aronica; Junpeng Deng; Paul L Fox; Muhammet Fatih Gulen; Thomas A Hamilton; Yue Han; Zizhen Kang; Xiaoxia Li
A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.

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All Publications

2012: Jarod A Zepp; Muhammet Fatih Gulen; Zizhen Kang; Caini Liu; Wen Qian; Ling Wu; Xiaoxia Li
Cutting edge: TNF receptor-associated factor 4 restricts IL-17-mediated pathology and signaling processes.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(1):33-7.
2011: Katarzyna Bulek; Muhammet Fatih Gulen; Thomas Hamilton; Vincent Hascall; Tomasz Herjan; Mark Lauer; Amina Abbadi; Mark A Aronica; Caini Liu; Saurav Misra; Richard C Page; Wen Qian; Dongxu Sun; Shadi Swaidani; Liwen Wang; Mark R Chance; Xiaoxia Li
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation.
Nature immunology 2011;12(9):844-52.
2011: Caini Liu; Saurav Misra; Wen Qian; Paige Sun; Shadi Swaidani; Chenhui Wang; Weiguo Yin; Chunjiang Zhang; Mark A Aronica; Junpeng Deng; Paul L Fox; Muhammet Fatih Gulen; Thomas A Hamilton; Yue Han; Zizhen Kang; Xiaoxia Li
A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.
Science signaling 2011;4(197):ra72.
2010: Zizhen Kang; Cengiz Z Altuntas; Muhammet Fatih Gulen; Caini Liu; Natalia Giltiay; Hongwei Qin; Liping Liu; Wen Qian; Richard M Ransohoff; Cornelia Bergmann; Stephen Stohlman; Vincent K Tuohy; Xiaoxia Li
Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis.
Immunity 2010;32(3):414-25.
2008: Hui Xiao; Wen Qian; Kirk Staschke; Youcun Qian; Grace Cui; Li Deng; maryam ehsani; Xiliang Wang; Yue-Wei Qian; Zhijian J Chen; Raymond Gilmour; Zhengfan Jiang; Xiaoxia Li
Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation.
The Journal of biological chemistry 2008;283(21):14654-64.
2007: Tae Whan Kim; Kirk Staschke; Katarzyna Bulek; Jianhong Yao; Kristi Peters; Keun-Hee Oh; Yvonne Vandenburg; Hui Xiao; Wen Qian; Tom Hamilton; Booki Min; Ganes Sen; Raymond Gilmour; Xiaoxia Li
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.
The Journal of experimental medicine 2007;204(5):1025-36.
2007: Jianhong Yao; Tae Whan Kim; Jianzhong Qin; Zhengfan Jiang; Youcun Qian; Hui Xiao; Yi Lu; Wen Qian; Muhammet Fatih Gulen; Nywana Sizemore; Joseph A DiDonato; Shintaro Sato; Shizuo Akira; Bing Su; Xiaoxia Li
Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification.
The Journal of biological chemistry 2007;282(9):6075-89.
2006: Kevin W Hallgren; Wen Qian; Anna V Yakubenko; Kurt Runge; Kathleen L Berkner
r-VKORC1 expression in factor IX BHK cells increases the extent of factor IX carboxylation but is limited by saturation of another carboxylation component or by a shift in the rate-limiting step.
Biochemistry 2006;45(17):5587-98.
2004: Mark A Rishavy; B Nirmala Pudota; Kevin W Hallgren; Wen Qian; Anna V Yakubenko; Jee-Hyeon Song; Kurt Runge; Kathleen L Berkner
A new model for vitamin K-dependent carboxylation: the catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(38):13732-7.