FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Youcun Qian

Research Profile

Chemicals & Drugs

Physiology

Living Beings

Co-author Network

Publications

TOP 3
Xinyang Song; Youcun Qian
Peli1 sets the CNS on fire.
Xinyang Song; Youcun Qian
The activation and regulation of IL-17 receptor mediated signaling.
Yikun Yao; Youcun Qian
Expression regulation and function of NLRC5.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Youcun Qian (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Xinyang Song; Youcun Qian
Peli1 sets the CNS on fire.
Nature medicine 2013;19(5):536-8.
2013: Xinyang Song; Youcun Qian
The activation and regulation of IL-17 receptor mediated signaling.
Cytokine 2013;62(2):175-82.
2013: Yikun Yao; Youcun Qian
Expression regulation and function of NLRC5.
Protein & cell 2013;4(3):168-75.
2012: Fangfang Qu; Peiqing Shi; Yufang Shi; Yihong Yao; Yifan Zhang; Shu Zhu; Hanchao Gao; Bahija Jallal; Yan Liu; Youcun Qian
TRAF6-dependent Act1 phosphorylation by the IκB kinase-related kinases suppresses interleukin-17-induced NF-κB activation.
Molecular and cellular biology 2012;32(19):3925-37.
2012: Shu Zhu; John B Harley; Dongyi He; Dong Liang; Wenjun Liu; Yan Liu; Wen Pan; Xinrui Shao; Nan Shen; Yufang Shi; Xinyang Song; Yuanjia Tang; Honglin Wang; Youcun Qian
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α.
Nature medicine 2012;18(7):1077-86.
2012: Shu Zhu; Youcun Qian
IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential.
Clinical science (London, England : 1979) 2012;122(11):487-511.
2012: Yikun Yao; Shu Zhu; Yufang Shi; Hongyan Wang; Yalong Wang; Fuxiang Chen; Yin Huang; Qibin Leng; Youcun Qian
NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens.
Cell research 2012;22(5):836-47.
2011: Xinyang Song; Shu Zhu; Steven D Levin; Yan Liu; Peiqing Shi; Yufang Shi; Youcun Qian
IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens.
Nature immunology 2011;12(12):1151-8.
2011: Peiqing Shi; Yufang Shi; Shu Zhu; Zhijian Chen; Yingying Lin; Yongfeng Liu; Yan Liu; Youcun Qian
Persistent stimulation with interleukin-17 desensitizes cells through SCFβ-TrCP-mediated degradation of Act1.
Science signaling 2011;4(197):ra73.
2010: Shu Zhu; Wen Pan; Peiqing Shi; Hanchao Gao; Fang Zhao; Xinyang Song; Yan Liu; Lihua Zhao; Xiaoxia Li; Yufang Shi; Youcun Qian
Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.
The Journal of experimental medicine 2010;207(12):2647-62.
2010: Youcun Qian; Zizhen Kang; Caini Liu; Xiaoxia Li
IL-17 signaling in host defense and inflammatory diseases.
Cellular & molecular immunology 2010;7(5):328-33.
2009: Youcun Qian; Yufang Shi
Natural killer cells go inside: entosis versus cannibalism.
Cell research 2009;19(12):1320-1.
2009: Caini Liu; Wen Qian; Youcun Qian; Natalia V Giltiay; Yi Lu; Shadi Swaidani; Saurav Misra; Li Deng; Zhijian J Chen; Xiaoxia Li
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.
Science signaling 2009;2(92):ra63.
2008: Youcun Qian; Natalia Giltiay; Jianhua Xiao; Yue Wang; Jun Tian; S Han; Martin Scott; Robert Carter; Trine N Jorgensen; Xiaoxia Li
Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome.
European journal of immunology 2008;38(8):2219-28.
2008: Hui Xiao; Wen Qian; Kirk Staschke; Youcun Qian; Grace Cui; Li Deng; maryam ehsani; Xiliang Wang; Yue-Wei Qian; Zhijian J Chen; Raymond Gilmour; Zhengfan Jiang; Xiaoxia Li
Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation.
The Journal of biological chemistry 2008;283(21):14654-64.
2007: Jianhong Yao; Tae Whan Kim; Jianzhong Qin; Zhengfan Jiang; Youcun Qian; Hui Xiao; Yi Lu; Wen Qian; Muhammet Fatih Gulen; Nywana Sizemore; Joseph A DiDonato; Shintaro Sato; Shizuo Akira; Bing Su; Xiaoxia Li
Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification.
The Journal of biological chemistry 2007;282(9):6075-89.
2007: Youcun Qian; Caini Liu; Justin Hartupee; Cengiz Z Altuntas; Muhammet Fatih Gulen; Daniel Jane-wit; Jianhua Xiao; Yi Lu; Natalia V Giltiay; Jinbo Liu; Tomasz Kordula; Qi-Wei Zhang; Bruce Vallance; Shadi Swaidani; Mark A Aronica; Vincent K Tuohy; Thomas Hamilton; Xiaoxia Li
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.
Nature immunology 2007;8(3):247-56.
2005: Jianzhong Qin; Youcun Qian; Jianhong Yao; Cui Grace; Xiaoxia Li
SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms.
The Journal of biological chemistry 2005;280(26):25233-41.
2004: Youcun Qian; Jianzhong Qin; Grace Cui; Mayumi Naramura; E Charles Snow; Carl Ware; Robert L Fairchild; Sidne A Omori; Robert C Rickert; Martin Scott; Brian L Kotzin; Xiaoxia Li
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival.
Immunity 2004;21(4):575-87.
2004: Jianzhong Qin; Zhengfan Jiang; Youcun Qian; Jean-Laurent Casanova; Xiaoxia Li
IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness.
The Journal of biological chemistry 2004;279(25):26748-53.
2003: David Wald; Jianzhong Qin; Zhendong Zhao; Youcun Qian; Mayumi Naramura; Liping Tian; Jennifer Towne; John E Sims; George R Stark; Xiaoxia Li
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.
Nature immunology 2003;4(9):920-7.
2003: Zhendong Zhao; Youcun Qian; Dave Wald; Yi-Feng Xia; Jian-Guo Geng; Xiaoxia Li
IFN regulatory factor-1 is required for the up-regulation of the CD40-NF-kappa B activator 1 axis during airway inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5674-80.
2002: Zhengfan Jiang; Jun Ninomiya-Tsuji; Youcun Qian; Kunihiro Matsumoto; Xiaoxia Li
Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol.
Molecular and cellular biology 2002;22(20):7158-67.
2002: Youcun Qian; Zhendong Zhao; Zhengfan Jiang; Xiaoxia Li
Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9386-91.
2001: Youcun Qian; Mairead Commane; Jun Ninomiya-Tsuji; K Matsumoto; Xiaoxia Li
IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B.
The Journal of biological chemistry 2001;276(45):41661-7.