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Li-Xuan Qin

Research Profile

Procedures

Devices

Oligonucleotide Array Sequence Analysis

Living Beings

Young Adult

Chemicals & Drugs

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Physiology

Gene Expression Regulation, Neoplastic

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Publications

TOP 3
Rebecca A Gladdy; Nicole Moraco; Li-Xuan Qin; Narasimhan P Agaram; Murray F Brennan; Samuel Singer
Predictors of survival and recurrence in primary leiomyosarcoma.
Gary K Schwartz; William D Tap; Samir D Undevia; Brian A Van Tine; Shyamprasad Deraje Vasudeva; Vincent Yim; Scott H Okuno; Li-Xuan Qin; Damon R Reed; Petra Rietschel; Scott M Schuetze; Abdul Abdullah; Douglas Adkins; Mark Agulnik; Cristina R Antonescu; Christiana Bitas; Bruce E Brockstein; Helen X Chen; Bartosz Chmielowski; Mercedes Condy; Mark A Dickson; L Austin Doyle; Alan L. Ho; Vicki Keedy; Andrew S Kraft; Michael B Livingston; Joseph A Ludwig; ROBERT G MAKI
Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.
Li-Xuan Qin; Tom Tuschl; Samuel Singer
An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study.

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All Publications

2013: Rebecca A Gladdy; Nicole Moraco; Li-Xuan Qin; Narasimhan P Agaram; Murray F Brennan; Samuel Singer
Predictors of survival and recurrence in primary leiomyosarcoma.
Annals of surgical oncology 2013;20(6):1851-7.
2013: Gary K Schwartz; William D Tap; Samir D Undevia; Brian A Van Tine; Shyamprasad Deraje Vasudeva; Vincent Yim; Scott H Okuno; Li-Xuan Qin; Damon R Reed; Petra Rietschel; Scott M Schuetze; Abdul Abdullah; Douglas Adkins; Mark Agulnik; Cristina R Antonescu; Christiana Bitas; Bruce E Brockstein; Helen X Chen; Bartosz Chmielowski; Mercedes Condy; Mark A Dickson; L Austin Doyle; Alan L. Ho; Vicki Keedy; Andrew S Kraft; Michael B Livingston; Joseph A Ludwig; ROBERT G MAKI
Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.
The lancet oncology 2013;14(4):371-82.
2013: Li-Xuan Qin; Tom Tuschl; Samuel Singer
An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study.
Cancer informatics 2013;12():83-101.
2013: Jennifer LaFemina; Nicole H Moraco; Li-Xuan Qin; Cristina R Antonescu; Murray F Brennan; Aimee M Crago; Ryan C Fields; Samuel Singer
Oncologic outcomes of sporadic, neurofibromatosis-associated, and radiation-induced malignant peripheral nerve sheath tumors.
Annals of surgical oncology 2013;20(1):66-72.
2012: Grazia Ambrosini; Richard Carvajal; Christine A Pratilas; Li-Xuan Qin; Oliver Surriga; Madhavi Tadi; Gary K Schwartz
Identification of unique MEK-dependent genes in GNAQ mutant uveal melanoma involved in cell growth, tumor cell invasion, and MEK resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(13):3552-61.
2012: Mary Morrogh; Monica Morrow; Asawari J Patil; Li-Xuan Qin; Rita Sakr; Victor P Andrade; Crispinita D Arroyo; Edi Brogi; Qianxing Mo; Tari A King
Differentially expressed genes in window trials are influenced by the wound-healing process: lessons learned from a pilot study with anastrozole.
The Journal of surgical research 2012;176(1):121-32.
2012: Aimee M Crago; Penelope DeCarolis; Rachael O'Connor; Li-Xuan Qin; Nicholas D Socci; Barry S Taylor; Cristina R Antonescu; Samuel Singer
Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(5):1334-40.
2012: Oren Cahlon; Xiaoyu Jia; Li-Xuan Qin; Samuel Singer; Murray F Brennan; Kaled M. Alektiar
A postoperative nomogram for local recurrence risk in extremity soft tissue sarcomas after limb-sparing surgery without adjuvant radiation.
Annals of surgery 2012;255(2):343-7.
2012: Junwei Chen; Ronald Dematteo; Tianhua Guo; ROBERT G MAKI; Li-Xuan Qin; Samuel Singer; Takahiro Taguchi; Lei Zhang; Peter Besmer; Cristina R Antonescu
CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers.
Genes, chromosomes & cancer 2012;51(2):186-95.
2011: Karin K Shih; Li-Xuan Qin; Edward J Tanner; Qin Zhou; Maria Bisogna; Fanny Dao; Narciso Olvera; Agnes Viale; Richard R Barakat; Douglas A Levine
A microRNA survival signature (MiSS) for advanced ovarian cancer.
Gynecologic oncology 2011;121(3):444-50.
2011: Ryan M Gobble; Li-Xuan Qin; Elliott R Brill; Christina V Angeles; Stacy Ugras; Rachael B O'Connor; Nicole H Moraco; Penelope DeCarolis; Cristina R Antonescu; Samuel Singer
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.
Cancer research 2011;71(7):2697-705.
2011: Ajay V Maker; Nora Katabi; Li-Xuan Qin; David S Klimstra; Mark Schattner; Murray F Brennan; William R Jarnagin; Peter J Allen
Cyst fluid interleukin-1beta (IL1beta) levels predict the risk of carcinoma in intraductal papillary mucinous neoplasms of the pancreas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1502-8.
2011: Ryan C Fields; Meera Hameed; Li-Xuan Qin; Nicole Moraco; Xiaoyu Jia; ROBERT G MAKI; Samuel Singer; Murray F Brennan
Dermatofibrosarcoma protuberans (DFSP): predictors of recurrence and the use of systemic therapy.
Annals of surgical oncology 2011;18(2):328-36.
2010: Iyare Esemuede; Ann Forslund; Sajid A Khan; Li-Xuan Qin; Mark I Gimbel; Garrett M Nash; Zhaoshi Zeng; Shoshana Rosenberg; Jinru Shia; Francis Barany; Philip B Paty
Improved testing for microsatellite instability in colorectal cancer using a simplified 3-marker assay.
Annals of surgical oncology 2010;17(12):3370-8.
2010: Brian H Kushner; Kim Kramer; Shakeel Modak; Li-Xuan Qin; Nai-Kong V Cheung
Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma.
Cancer 2010;116(12):3054-60.
2010: Rebecca A Gladdy; Li-Xuan Qin; Nicole Moraco; Mark A Edgar; Cristina R Antonescu; Kaled M. Alektiar; Murray F Brennan; Samuel Singer
Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(12):2064-9.
2009: James Park; Li-Xuan Qin; Francesco P Prete; Cristina R Antonescu; Murray F Brennan; Samuel Singer
Predicting outcome by growth rate of locally recurrent retroperitoneal liposarcoma: the one centimeter per month rule.
Annals of surgery 2009;250(6):977-82.
2009: Peter J Allen; Li-Xuan Qin; Laura H Tang; David S Klimstra; Murray F Brennan; Anna Lokshin
Pancreatic cyst fluid protein expression profiling for discriminating between serous cystadenoma and intraductal papillary mucinous neoplasm.
Annals of surgery 2009;250(5):754-60.
2009: James Korkola; Jane Houldsworth; Darren R Feldman; Adam B Olshen; Li-Xuan Qin; Sujata M Patil; Victor E Reuter; George J Bosl; Raju S K Chaganti
Identification and validation of a gene expression signature that predicts outcome in adult men with germ cell tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(31):5240-7.
2009: Cristina R Antonescu; Akihiko Yoshida; Tianhuo Guo; Ning-En Chang; Lei Zhang; Narasimhan P Agaram; Li-Xuan Qin; Murray F Brennan; Samuel Singer; ROBERT G MAKI
KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors.
Cancer research 2009;69(18):7175-9.
2009: Lihong Li; Yong Lu; Li-Xuan Qin; Ziv Bar-Joseph; Margaret Werner-Washburne; Linda L Breeden
Budding yeast SSD1-V regulates transcript levels of many longevity genes and extends chronological life span in purified quiescent cells.
Molecular biology of the cell 2009;20(17):3851-64.
2009: Minaxi Jhawer; Daniel G Coit; Murray F Brennan; Li-Xuan Qin; Mithat Gonen; David S Klimstra; Laura H Tang; David P Kelsen; Manish A Shah
Perineural invasion after preoperative chemotherapy predicts poor survival in patients with locally advanced gastric cancer: gene expression analysis with pathologic validation.
American journal of clinical oncology 2009;32(4):356-62.
2009: ROBERT G MAKI; David R D'Adamo; Mary-Louise Keohan; Michael Saulle; Scott M Schuetze; Samir D Undevia; Michael B Livingston; Matthew M Cooney; Martee Hensley; Monica Mita; Chris H Takimoto; Andrew Kraft; Anthony D Elias; Bruce E Brockstein; Nathalie E Blachère; Mark A Edgar; Lawrence H Schwartz; Li-Xuan Qin; Cristina R Antonescu; Gary K Schwartz
Phase II study of sorafenib in patients with metastatic or recurrent sarcomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(19):3133-40.
2009: Brian H Kushner; Kim Kramer; Shakeel Modak; Li-Xuan Qin; Karima Yataghena; Suresh C Jhanwar; Nai-Kong V Cheung
Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma.
Pediatric blood & cancer 2009;53(1):17-22.
2009: Peter B Gilbert; Li-Xuan Qin; Steven G Self
Response to Andrew Dunning's comment on 'evaluating a surrogate endpoint at three levels, with application to vaccine development'.
Statistics in medicine 2009;28(4):716-9.
2009: Raymond De Meng; Christopher C Shelton; Yueming Li; Li-Xuan Qin; Daniel A Notterman; Philip B Paty; Gary K Schwartz
gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
Cancer research 2009;69(2):573-82.
2009: Timothy Gershon; Arash Shirazi; Li-Xuan Qin; William L Gerald; Anna Marie Kenney; Nai-Kong V Cheung
Enteric neural crest differentiation in ganglioneuromas implicates Hedgehog signaling in peripheral neuroblastic tumor pathogenesis.
PloS one 2009;4(10):e7491.
2009: Li-Xuan Qin; Jaya M Satagopan
Normalization method for transcriptional studies of heterogeneous samples--simultaneous array normalization and identification of equivalent expression.
Statistical applications in genetics and molecular biology 2009;8():Article 10.
2008: Robert Canter; Li-Xuan Qin; ROBERT G MAKI; Murray F Brennan; Marc Ladanyi; Samuel Singer
A synovial sarcoma-specific preoperative nomogram supports a survival benefit to ifosfamide-based chemotherapy and improves risk stratification for patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(24):8191-7.
2008: Robert Canter; Li-Xuan Qin; Cristina R Ferrone; ROBERT G MAKI; Samuel Singer; Murray F Brennan
Why do patients with low-grade soft tissue sarcoma die?
Annals of surgical oncology 2008;15(12):3550-60.
2008: Peter B Gilbert; Li-Xuan Qin; Steven G Self
Evaluating a surrogate endpoint at three levels, with application to vaccine development.
Statistics in medicine 2008;27(23):4758-78.
2008: Grazia Ambrosini; Sharon L Seelman; Li-Xuan Qin; Gary K Schwartz
The cyclin-dependent kinase inhibitor flavopiridol potentiates the effects of topoisomerase I poisons by suppressing Rad51 expression in a p53-dependent manner.
Cancer research 2008;68(7):2312-20.
2008: Hikmat Al-Ahmadie; Darym Alden; Li-Xuan Qin; Semra Olgac; Samson W Fine; Anuradha Gopalan; Paul Russo; Robert J Motzer; Victor E Reuter; SK Tickoo
Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies.
The American journal of surgical pathology 2008;32(3):377-82.
2008: Ann Forslund; Zhaoshi Zeng; Li-Xuan Qin; Shoshana Rosenberg; MacKevin Ndubuisi; Hanna Pincas; William Gerald; Daniel A Notterman; Francis Barany; Philip B Paty
MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers.
Molecular cancer research : MCR 2008;6(2):205-11.
2008: Li-Xuan Qin
An integrative analysis of microRNA and mRNA expression--a case study.
Cancer informatics 2008;6():369-79.
2007: Robert Canter; Li-Xuan Qin; Robert J Downey; Murray F Brennan; Samuel Singer; ROBERT G MAKI
Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysis.
Cancer 2007;110(9):2050-60.
2006: Li-Xuan Qin; Steven G Self
The clustering of regression models method with applications in gene expression data.
Biometrics 2006;62(2):526-33.
2006: Li-Xuan Qin; Richard P Beyer; Francesca N Hudson; Nancy J Linford; Daryl E Morris; Kathleen F Kerr
Evaluation of methods for oligonucleotide array data via quantitative real-time PCR.
BMC bioinformatics 2006;7():23.
2005: Theodore Bammler; Richard P Beyer; Sanchita Bhattacharya; Gary A Boorman; Abee Boyles; Blair U Bradford; Roger Bumgarner; Pierre R Bushel; Kabir Chaturvedi; Dongseok Choi; Michael L Cunningham; Shibing Deng; Holly K Dressman; Rickie D Fannin; Fredrico M Farin; Jonathan H Freedman; Rebecca Fry; Angel Harper; Michael C Humble; Patrick Hurban; Terrance J Kavanagh; William K Kaufmann; Kathleen F Kerr; Li Jing; Jodi A Lapidus; Michael R Lasarev; Jianying Li; Yi-Ju Li; Edward K Lobenhofer; Xinfang Lu; Renae L Malek; Sean Milton; Srinivasa R Nagalla; Jean P O'malley; Valerie S Palmer; Patrick Pattee; Richard S Paules; Charles M Perou; Ken Phillips; Li-Xuan Qin; Yang Qiu; Sean D Quigley; Matthew Rodland; Ivan Rusyn; Leona D Samson; David A Schwartz; Yan Shi; Jung-Lim Shin; Stella O Sieber; Susan Slifer; Marcy C Speer; Peter S Spencer; Dean I Sproles; James A Swenberg; William A Suk; Robert C Sullivan; Ru Tian; Raymond W Tennant; Signe A Todd; Charles J Tucker; Bennett Van Houten; Brenda K Weis; Shirley Xuan; Helmut Zarbl
Standardizing global gene expression analysis between laboratories and across platforms.
Nature methods 2005;2(5):351-6.
2004: Li-Xuan Qin; Kathleen F Kerr
Empirical evaluation of data transformations and ranking statistics for microarray analysis.
Nucleic acids research 2004;32(18):5471-9.