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Darryl Quarles

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Hala M Alshayeb; Therese Mangold; Arif Showkat; Barry M Wall; L Darryl Quarles
Chronic kidney disease and diabetes mellitus predict resistance to vitamin D replacement therapy.
L Darryl Quarles
A systems biology preview of the relationships between mineral and metabolic complications in chronic kidney disease.
L Darryl Quarles
Reducing cardiovascular mortality in chronic kidney disease: something borrowed, something new.

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2013: Hala M Alshayeb; Therese Mangold; Arif Showkat; Barry M Wall; L Darryl Quarles
Chronic kidney disease and diabetes mellitus predict resistance to vitamin D replacement therapy.
The American journal of the medical sciences 2013;345(4):314-20.
2013: L Darryl Quarles
A systems biology preview of the relationships between mineral and metabolic complications in chronic kidney disease.
Seminars in nephrology 2013;33(2):130-42.
2013: L Darryl Quarles
Reducing cardiovascular mortality in chronic kidney disease: something borrowed, something new.
The Journal of clinical investigation 2013;123(2):542-3.
2012: A Martin; B Dai; V David; J Q Feng; H Li; L Darryl Quarles
Overexpression of the DMP1 C-terminal fragment stimulates FGF23 and exacerbates the hypophosphatemic rickets phenotype in Hyp mice.
Molecular endocrinology (Baltimore, Md.) 2012;26(11):1883-95.
2012: Bing Dai; Valentin David; Geeta Gyamlani; Ronald L Horst; Arif Showkat; Barry M Wall; Hala M Alshayeb; L Darryl Quarles
Assessment of 24,25(OH)2D levels does not support FGF23-mediated catabolism of vitamin D metabolites.
Kidney international 2012;82(10):1061-70.
2012: Min Pi; Ivan C Gerling; Nataliya I Lenchik; Yunpeng Wu; L Darryl Quarles
GPRC6A mediates the effects of L-arginine on insulin secretion in mouse pancreatic islets.
Endocrinology 2012;153(10):4608-15.
2012: Erik C Dreaden; Lauren A Austin; Berkley E Gryder; Steven C Hayden; Adegboyega K Oyelere; Min Pi; L Darryl Quarles; Brice A Tene Defo; Mostafa A El-Sayed
Antiandrogen gold nanoparticles dual-target and overcome treatment resistance in hormone-insensitive prostate cancer cells.
Bioconjugate chemistry 2012;23(8):1507-12.
2012: L Darryl Quarles
Role of FGF23 in vitamin D and phosphate metabolism: implications in chronic kidney disease.
Experimental cell research 2012;318(9):1040-8.
2012: Min Pi; L Darryl Quarles
Multiligand specificity and wide tissue expression of GPRC6A reveals new endocrine networks.
Endocrinology 2012;153(5):2062-9.
2012: L Darryl Quarles
Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism.
Nature reviews. Endocrinology 2012;8(5):276-86.
2012: Ni Qiu; Meagan M Buechel; Li Cao; Valentin David; Esra Roan; Zhousheng Xiao; L Darryl Quarles
Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia.
Journal of cell science 2012;125(Pt 8):1945-57.
2012: Min Pi; L Darryl Quarles
GPRC6A regulates prostate cancer progression.
The Prostate 2012;72(4):399-409.
2012: Bing Dai; Valentin David; Weikuan Gu; Jinsong Huang; Yan Jiao; Hua Li; Aline Martin; L Darryl Quarles
A comparative transcriptome analysis identifying FGF23 regulated genes in the kidney of a mouse CKD model.
PloS one 2012;7(9):e44161.
2012: Aline Martin; L Darryl Quarles
Evidence for FGF23 involvement in a bone-kidney axis regulating bone mineralization and systemic phosphate and vitamin D homeostasis.
Advances in experimental medicine and biology 2012;728():65-83.
2012: Aline Martin; Valentin David; L Darryl Quarles
Regulation and function of the FGF23/klotho endocrine pathways.
Physiological reviews 2012;92(1):131-55.
2012: Jason R Stubbs; Valentin David; Ryan Gillihan; Nan He; Yan Hong; Arun Idiculla; Shiguang Liu; L Darryl Quarles
Longitudinal evaluation of FGF23 changes and mineral metabolism abnormalities in a mouse model of chronic kidney disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(1):38-46.
2011: Zhousheng Xiao; Lynda Bonewald; Li Cao; Mark Dallas; Mark Johnson; Daniel Nicolella; Ni Qiu; L Darryl Quarles
Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(7):2418-32.
2011: Min Pi; Yunpeng Wu; L Darryl Quarles
GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(7):1680-3.
2011: L Darryl Quarles
The bone and beyond: 'Dem bones' are made for more than walking.
Nature medicine 2011;17(4):428-30.
2011: Hua Li; Aline Martin; Valentin David; L Darryl Quarles
Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.
American journal of physiology. Endocrinology and metabolism 2011;300(3):E508-17.
2011: Nan He; Zhousheng Xiao; Tong Yin; Jason Stubbs; Linheng Li; L Darryl Quarles
Inducible expression of Runx2 results in multiorgan abnormalities in mice.
Journal of cellular biochemistry 2011;112(2):653-65.
2011: James B Wetmore; Peter W Santos; Jonathan D Mahnken; Ron Krebill; Rochelle Menard; Hema Gutta; L Darryl Quarles
Elevated FGF23 levels are associated with impaired calcium-mediated suppression of PTH in ESRD.
The Journal of clinical endocrinology and metabolism 2011;96(1):E57-64.
2010: Min Pi; Abby L Parrill; L Darryl Quarles
GPRC6A mediates the non-genomic effects of steroids.
The Journal of biological chemistry 2010;285(51):39953-64.
2010: Theresa I Shireman; Ammar Almehmi; James B Wetmore; John Lu; Mark Pregenzer; L Darryl Quarles
Economic analysis of cinacalcet in combination with low-dose vitamin D versus flexible-dose vitamin D in treating secondary hyperparathyroidism in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2010;56(6):1108-16.
2010: Min Pi; Lishu Zhang; Shu-Feng Lei; Min-Zhao Huang; Wenyu Zhu; Jianghong Zhang; Hui Shen; Hong-Wen Deng; L Darryl Quarles
Impaired osteoblast function in GPRC6A null mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(5):1092-102.
2010: Valentin David; L Darryl Quarles
ASARM mineralization hypothesis: a bridge too far?
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(4):692-4.
2010: Zhou-Sheng Xiao; L Darryl Quarles
Role of the polycytin-primary cilia complex in bone development and mechanosensing.
Annals of the New York Academy of Sciences 2010;1192():410-21.
2010: Jason R Stubbs; Arun Idiculla; Joyce Slusser; Rochelle Menard; L Darryl Quarles
Cholecalciferol supplementation alters calcitriol-responsive monocyte proteins and decreases inflammatory cytokines in ESRD.
Journal of the American Society of Nephrology : JASN 2010;21(2):353-61.
2010: Zhousheng Xiao; Shiqin Zhang; Li Cao; Ni Qiu; Valentin David; L Darryl Quarles
Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation.
The Journal of biological chemistry 2010;285(2):1177-87.
2010: Ni Qiu; Li Cao; Valentin David; L Darryl Quarles; Zhousheng Xiao
Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis.
PloS one 2010;5(12):e15240.
2010: James B Wetmore; Shiguang Liu; Ron Krebill; Rochelle Menard; L Darryl Quarles
Effects of cinacalcet and concurrent low-dose vitamin D on FGF23 levels in ESRD.
Clinical journal of the American Society of Nephrology : CJASN 2010;5(1):110-6.
2009: Shiqin Zhang; Zhousheng Xiao; Junming Luo; Nan He; Josh Mahlios; L Darryl Quarles
Dose-dependent effects of Runx2 on bone development.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(11):1889-904.
2009: Shiguang Liu; Wen Tang; Jianwen Fang; Jinyu Ren; Hua Li; Zhousheng Xiao; L Darryl Quarles
Novel regulators of Fgf23 expression and mineralization in Hyp bone.
Molecular endocrinology (Baltimore, Md.) 2009;23(9):1505-18.
2009: Jason R Stubbs; L Darryl Quarles
Fibroblast growth factor 23: uremic toxin or innocent bystander in chronic kidney disease?
Nephrology news & issues 2009;23(6):33-4, 36-7.
2008: L Darryl Quarles
Endocrine functions of bone in mineral metabolism regulation.
The Journal of clinical investigation 2008;118(12):3820-8.
2008: Min Pi; Ling Chen; MinZhao Huang; Qiang Luo; L Darryl Quarles
Parathyroid-specific interaction of the calcium-sensing receptor and G alpha q.
Kidney international 2008;74(12):1548-56.
2008: Shiguang Liu; Luke Vierthaler; Wen Tang; Jianping Zhou; L Darryl Quarles
FGFR3 and FGFR4 do not mediate renal effects of FGF23.
Journal of the American Society of Nephrology : JASN 2008;19(12):2342-50.
2008: Qing-Chuan Liao; Ya-Lin Li; Yan-Fang Qin; L Darryl Quarles; Kang-Kang Xu; Rong Li; Hong-Hao Zhou; Zhou-Sheng Xiao
Inhibition of adipocyte differentiation by phytoestrogen genistein through a potential downregulation of extracellular signal-regulated kinases 1/2 activity.
Journal of cellular biochemistry 2008;104(5):1853-64.
2008: Zhousheng Xiao; Shiqin Zhang; Brenda S Magenheimer; Junming Luo; L Darryl Quarles
Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.
The Journal of biological chemistry 2008;283(18):12624-34.
2008: Uri S Alon; Rachel Levy-Olomucki; Wayne V Moore; Jason Stubbs; Shiguang Liu; L Darryl Quarles
Calcimimetics as an adjuvant treatment for familial hypophosphatemic rickets.
Clinical journal of the American Society of Nephrology : CJASN 2008;3(3):658-64.
2008: James B Wetmore; L Darryl Quarles
Treatment of secondary hyperparathyroidism in kidney disease: what we know and do not know about use of calcimimetics and vitamin D analogs.
International journal of nephrology and renovascular disease 2008;1():5-17.
2008: Min Pi; Ling Chen; Min-Zhao Huang; Wenyu Zhu; Brian Ringhofer; Junming Luo; Lane K Christenson; Benyi Li; Jianghong Zhang; P David Jackson; Pieter Faber; Kurt R Brunden; John J Harrington; L Darryl Quarles
GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome.
PloS one 2008;3(12):e3858.
2007: Shiguang Liu; Wen Tang; Jianping Zhou; Luke Vierthaler; L Darryl Quarles
Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice.
American journal of physiology. Endocrinology and metabolism 2007;293(6):E1636-44.
2007: Ya Lin Li; L Darryl Quarles; Hong-Hao Zhou; Zhou-Sheng Xiao
RNA interference and its application in bone-related diseases.
Biochemical and biophysical research communications 2007;361(4):817-21.
2007: Jason R Stubbs; Shiguang Liu; L Darryl Quarles
Role of fibroblast growth factor 23 in phosphate homeostasis and pathogenesis of disordered mineral metabolism in chronic kidney disease.
Seminars in dialysis 2007;20(4):302-8.
2007: Shiguang Liu; Aditi Gupta; L Darryl Quarles
Emerging role of fibroblast growth factor 23 in a bone-kidney axis regulating systemic phosphate homeostasis and extracellular matrix mineralization.
Current opinion in nephrology and hypertension 2007;16(4):329-35.
2007: Jason R Stubbs; Shiguang Liu; Wen Tang; Jianping Zhou; Yong Wang; Xiaomei Yao; L Darryl Quarles
Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice.
Journal of the American Society of Nephrology : JASN 2007;18(7):2116-24.
2007: Shiguang Liu; L Darryl Quarles
How fibroblast growth factor 23 works.
Journal of the American Society of Nephrology : JASN 2007;18(6):1637-47.
2007: Shiguang Liu; Peter S N Rowe; Luke Vierthaler; Jianping Zhou; L Darryl Quarles
Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity.
The Journal of endocrinology 2007;192(1):261-7.
2006: Jian Q Feng; Leanne M Ward; Shiguang Liu; Yongbo Lu; Yixia Xie; Baozhi Yuan; Xijie Yu; Frank Rauch; Siobhan I Davis; Shubin Zhang; Hector Rios; Marc K Drezner; L Darryl Quarles; Lynda F Bonewald; Kenneth E White
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.
Nature genetics 2006;38(11):1310-5.
2006: Zhousheng Xiao; Shiqin Zhang; Josh Mahlios; Gan Zhou; Brenda S Magenheimer; Dayong Guo; Sarah L Dallas; Robin L Maser; James P Calvet; Lynda F Bonewald; L Darryl Quarles
Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression.
The Journal of biological chemistry 2006;281(41):30884-95.
2006: Li Hua Song; Wei Pan; Yan Hui Yu; L Darryl Quarles; Hong-Hao Zhou; Zhou-Sheng Xiao
Resveratrol prevents CsA inhibition of proliferation and osteoblastic differentiation of mouse bone marrow-derived mesenchymal stem cells through an ER/NO/cGMP pathway.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(6):915-22.
2006: Shiguang Liu; Jianping Zhou; Wen Tang; Xi Jiang; David W Rowe; L Darryl Quarles
Pathogenic role of Fgf23 in Hyp mice.
American journal of physiology. Endocrinology and metabolism 2006;291(1):E38-49.
2006: Joachim H Ix; L Darryl Quarles; Glenn M Chertow
Guidelines for disorders of mineral metabolism and secondary hyperparathyroidism should not yet be modified.
Nature clinical practice. Nephrology 2006;2(6):337-9.
2006: Shiguang Liu; Wen Tang; Jianping Zhou; Jason R Stubbs; Qiang Luo; Min Pi; L Darryl Quarles
Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D.
Journal of the American Society of Nephrology : JASN 2006;17(5):1305-15.
2006: James B Wetmore; L Darryl Quarles
Oral paricalcitol: a viewpoint by james B. Wetmore and L. Darryl quarles.
Treatments in endocrinology 2006;5(5):326-7.
2005: Min Pi; Pieter Faber; George Ekema; P David Jackson; Anthony Ting; Nancy Wang; Michelle Fontilla-Poole; Robert Mays; Kurt R Brunden; John J Harrington; L Darryl Quarles
Identification of a novel extracellular cation-sensing G-protein-coupled receptor.
The Journal of biological chemistry 2005;280(48):40201-9.
2005: Min Pi; L Darryl Quarles
Osteoblast calcium-sensing receptor has characteristics of ANF/7TM receptors.
Journal of cellular biochemistry 2005;95(6):1081-92.
2005: Zhousheng Xiao; Hani A Awad; Shiguang Liu; Josh Mahlios; Shiqin Zhang; Farshid Guilak; Matthew S Mayo; L Darryl Quarles
Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice.
Developmental biology 2005;283(2):345-56.
2005: L Darryl Quarles
Cinacalcet HCl: a novel treatment for secondary hyperparathyroidism in stage 5 chronic kidney disease.
Kidney international. Supplement 2005;(96):S24-8.
2005: Shiguang Liu; Thomas Brown; Jianping Zhou; Zhou-Sheng Xiao; Hani Awad; Farshid Guilak; L Darryl Quarles
Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia.
Journal of the American Society of Nephrology : JASN 2005;16(6):1645-53.
2005: Min Pi; Robert H Oakley; Diane Gesty-Palmer; Rachael D Cruickshank; Robert F Spurney; Louis M Luttrell; L Darryl Quarles
Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization.
Molecular endocrinology (Baltimore, Md.) 2005;19(4):1078-87.
2005: Liming Wang; Shiguang Liu; L Darryl Quarles; Robert F Spurney
Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss.
American journal of physiology. Endocrinology and metabolism 2005;288(4):E826-34.
2005: Sharon M Moe; Glenn M Chertow; Jack W Coburn; L Darryl Quarles; William G Goodman; Geoffrey A Block; Tilman B Drüeke; John Cunningham; Donald J Sherrard; Laura C McCary; Kurt A Olson; Stewart A Turner; Kevin J Martin
Achieving NKF-K/DOQI bone metabolism and disease treatment goals with cinacalcet HCl.
Kidney international 2005;67(2):760-71.
2005: Wei Pan; L Darryl Quarles; Li-Hua Song; Yan-Hui Yu; Chen Jiao; Hong-Bo Tang; Chang-Hong Jiang; Han-Wu Deng; Yuan-Jian Li; Hong-Hao Zhou; Zhou-Sheng Xiao
Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture.
Journal of cellular biochemistry 2005;94(2):307-16.
2004: Liming Wang; L Darryl Quarles; Robert F Spurney
Unmasking the osteoinductive effects of a G-protein-coupled receptor (GPCR) kinase (GRK) inhibitor by treatment with PTH(1-34).
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(10):1661-70.
2004: Zhou-Sheng Xiao; Anita B Hjelmeland; L Darryl Quarles
Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis.
The Journal of biological chemistry 2004;279(19):20307-13.
2004: Min Pi; L Darryl Quarles
A novel cation-sensing mechanism in osteoblasts is a molecular target for strontium.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(5):862-9.
2003: Qisheng Tu; Min Pi; L Darryl Quarles
Calcyclin mediates serum response element (SRE) activation by an osteoblastic extracellular cation-sensing mechanism.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(10):1825-33.
2003: Shiguang Liu; Rong Guo; Leigh G Simpson; Zhou-Sheng Xiao; Charles E Burnham; L Darryl Quarles
Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX.
The Journal of biological chemistry 2003;278(39):37419-26.
2003: L Darryl Quarles
Evidence for a bone-kidney axis regulating phosphate homeostasis.
The Journal of clinical investigation 2003;112(5):642-6.
2003: Thomas J Weber; Shiguang Liu; Olafur S Indridason; L Darryl Quarles
Serum FGF23 levels in normal and disordered phosphorus homeostasis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(7):1227-34.
2003: L Darryl Quarles
Extracellular calcium-sensing receptors in the parathyroid gland, kidney, and other tissues.
Current opinion in nephrology and hypertension 2003;12(4):349-55.
2003: L Darryl Quarles
FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization.
American journal of physiology. Endocrinology and metabolism 2003;285(1):E1-9.
2003: Xiaowei Chen; Sanford C Garner; L Darryl Quarles; John J B Anderson
Effects of genistein on expression of bone markers during MC3T3-E1 osteoblastic cell differentiation.
The Journal of nutritional biochemistry 2003;14(6):342-9.
2003: Qisheng Tu; Min Pi; Gerard Karsenty; Leigh Simpson; Shiguang Liu; L Darryl Quarles
Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background.
The Journal of clinical investigation 2003;111(7):1029-37.
2003: L Darryl Quarles; Donald J Sherrard; Stephen Adler; Steven J Rosansky; Laura C McCary; Wei Liu; Stewart A Turner; David A Bushinsky
The calcimimetic AMG 073 as a potential treatment for secondary hyperparathyroidism of end-stage renal disease.
Journal of the American Society of Nephrology : JASN 2003;14(3):575-83.
2003: Zhou-Sheng Xiao; Leigh G Simpson; L Darryl Quarles
IRES-dependent translational control of Cbfa1/Runx2 expression.
Journal of cellular biochemistry 2003;88(3):493-505.
2002: Min Pi; Robert F Spurney; Qisheng Tu; Todd Hinson; L Darryl Quarles
Calcium-sensing receptor activation of rho involves filamin and rho-guanine nucleotide exchange factor.
Endocrinology 2002;143(10):3830-8.
2002: Rong Guo; Peter S N Rowe; Shiguang Liu; Leigh G Simpson; Zhou-Sheng Xiao; L Darryl Quarles
Inhibition of MEPE cleavage by Phex.
Biochemical and biophysical research communications 2002;297(1):38-45.
2002: Olafur S Indridason; L Darryl Quarles
Hyperphosphatemia in end-stage renal disease.
Advances in renal replacement therapy 2002;9(3):184-92.
2002: L Darryl Quarles
Introduction: emerging therapies derived from the molecular pathogenesis of secondary hyperparathyroidism in ESRD patients.
Advances in renal replacement therapy 2002;9(3):153-8.
2002: Robert F Spurney; Patrick J Flannery; Sanford C Garner; Krairerk Athirakul; Shiguang Liu; Farshid Guilak; L Darryl Quarles
Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in osteoblasts.
The Journal of clinical investigation 2002;109(10):1361-71.
2002: Shiguang Liu; Rong Guo; Qisheng Tu; L Darryl Quarles
Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype.
The Journal of biological chemistry 2002;277(5):3686-97.
2001: Zhou-Sheng Xiao; L Darryl Quarles; Qing-Quan Chen; Yan-Hui Yu; X P Qu; Chang-Hong Jiang; Han-Wu Deng; Yuan-Jian Li; Hong-Hao Zhou
Effect of asymmetric dimethylarginine on osteoblastic differentiation.
Kidney international 2001;60(5):1699-704.
2001: Rong Guo; Shiguang Liu; Robert F Spurney; L Darryl Quarles
Analysis of recombinant Phex: an endopeptidase in search of a substrate.
American journal of physiology. Endocrinology and metabolism 2001;281(4):E837-47.
2001: Sanford C Garner; Min Pi; Qisheng Tu; L Darryl Quarles
Rickets in cation-sensing receptor-deficient mice: an unexpected skeletal phenotype.
Endocrinology 2001;142(9):3996-4005.
2001: Shiguang Liu; Rong Guo; L Darryl Quarles
Cloning and characterization of the proximal murine Phex promoter.
Endocrinology 2001;142(9):3987-95.
2001: L Darryl Quarles; Marc K Drezner
Pathophysiology of X-linked hypophosphatemia, tumor-induced osteomalacia, and autosomal dominant hypophosphatemia: a perPHEXing problem.
The Journal of clinical endocrinology and metabolism 2001;86(2):494-6.
2001: Zhou-Sheng Xiao; S G Liu; Todd Hinson; L Darryl Quarles
Characterization of the upstream mouse Cbfa1/Runx2 promoter.
Journal of cellular biochemistry 2001;82(4):647-59.
2000: Min Pi; Sanford C Garner; Patrick J Flannery; Robert F Spurney; L Darryl Quarles
Sensing of extracellular cations in CasR-deficient osteoblasts. Evidence for a novel cation-sensing mechanism.
The Journal of biological chemistry 2000;275(5):3256-63.
2000: Thomas J Weber; L Darryl Quarles
Preventing bone loss after renal transplantation with bisphosphonates: we can... but should we?
Kidney international 2000;57(2):735-7.
2000: Olafur S Indridason; L Darryl Quarles
Comparison of treatments for mild secondary hyperparathyroidism in hemodialysis patients. Durham Renal Osteodystrophy Study Group.
Kidney international 2000;57(1):282-92.
1999: T Nesbitt; I Fujiwara; R Thomas; Zhou-Sheng Xiao; L Darryl Quarles; Marc K Drezner
Coordinated maturational regulation of PHEX and renal phosphate transport inhibitory activity: evidence for the pathophysiological role of PHEX in X-linked hypophosphatemia.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(12):2027-35.
1999: Peter J Conlon; Kelvin L Lynn; Michelle P Winn; L Darryl Quarles; ML Bembe; Margaret Pericak-Vance; M Speer; David N Howell
Spectrum of disease in familial focal and segmental glomerulosclerosis.
Kidney international 1999;56(5):1863-71.
1999: Zhou-Sheng Xiao; Todd Hinson; L Darryl Quarles
Cbfa1 isoform overexpression upregulates osteocalcin gene expression in non-osteoblastic and pre-osteoblastic cells.
Journal of cellular biochemistry 1999;74(4):596-605.
1999: Min Pi; Todd Hinson; L Darryl Quarles
Failure to detect the extracellular calcium-sensing receptor (CasR) in human osteoblast cell lines.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(8):1310-9.
1999: Michelle P Winn; Peter J Conlon; Kelvin L Lynn; David N Howell; BD Slotterbeck; A H Smith; Felicia L Graham; ML Bembe; L Darryl Quarles; Margaret Pericak-Vance; Jeffery Vance
Linkage of a gene causing familial focal segmental glomerulosclerosis to chromosome 11 and further evidence of genetic heterogeneity.
Genomics 1999;58(2):113-20.
1999: Robert F Spurney; Min Pi; Patrick J Flannery; L Darryl Quarles
Aluminum is a weak agonist for the calcium-sensing receptor.
Kidney international 1999;55(5):1750-8.
1999: Michelle P Winn; Peter J Conlon; Kelvin L Lynn; David N Howell; D A Gross; AR Rogala; A H Smith; Felicia L Graham; ML Bembe; L Darryl Quarles; Margaret Pericak-Vance; Jeffery Vance
Clinical and genetic heterogeneity in familial focal segmental glomerulosclerosis. International Collaborative Group for the Study of Familial Focal Segmental Glomerulosclerosis.
Kidney international 1999;55(4):1241-6.
1998: Olafur S Indridason; C F Pieper; L Darryl Quarles
Predictors of short-term changes in serum intact parathyroid hormone levels in hemodialysis patients: role of phosphorus, calcium, and gender.
The Journal of clinical endocrinology and metabolism 1998;83(11):3860-6.
1998: Zhou-Sheng Xiao; M Crenshaw; Rong Guo; T Nesbitt; Marc K Drezner; L Darryl Quarles
Intrinsic mineralization defect in Hyp mouse osteoblasts.
The American journal of physiology 1998;275(4 Pt 1):E700-8.
1998: Zhou-Sheng Xiao; R Thomas; Todd Hinson; L Darryl Quarles
Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor.
Gene 1998;214(1-2):187-97.
1997: Sanford C Garner; Todd Hinson; K S McCarty; M Leight; George S Leight; L Darryl Quarles
Quantitative analysis of the calcium-sensing receptor messenger RNA in parathyroid adenomas.
Surgery 1997;122(6):1166-75.
1997: Todd Hinson; Tirupapuliyur V Damodaran; J Chen; X Zhang; Mazin B Qumsiyeh; Michael F Seldin; L Darryl Quarles
Identification of putative transmembrane receptor sequences homologous to the calcium-sensing G-protein-coupled receptor.
Genomics 1997;45(2):279-89.
1997: Rong Guo; L Darryl Quarles
Cloning and sequencing of human PEX from a bone cDNA library: evidence for its developmental stage-specific regulation in osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(7):1009-17.
1997: L Darryl Quarles; S R Siddhanti; S Medda
Developmental regulation of osteocalcin expression in MC3T3-E1 osteoblasts: minimal role of the proximal E-box cis-acting promoter elements.
Journal of cellular biochemistry 1997;65(1):11-24.
1997: L Darryl Quarles; J E Hartle; S R Siddhanti; Rong Guo; Todd Hinson
A distinct cation-sensing mechanism in MC3T3-E1 osteoblasts functionally related to the calcium receptor.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(3):393-402.
1996: Olafur S Indridason; H Heath; S Khosla; D A Yohay; L Darryl Quarles
Non-suppressible parathyroid hormone secretion is related to gland size in uremic secondary hyperparathyroidism.
Kidney international 1996;50(5):1663-71.
1996: L Darryl Quarles; S R Siddhanti
Guanine nucleotide binding-protein coupled signaling pathway regulation of osteoblast-mediated bone formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(10):1375-83.
1996: L Darryl Quarles; Olafur S Indridason
Calcitriol administration in end-stage renal disease: intravenous or oral?
Pediatric nephrology (Berlin, Germany) 1996;10(3):331-6.
1996: J E Hartle; Veronica Prpic; S R Siddhanti; Robert F Spurney; L Darryl Quarles
Differential regulation of receptor-stimulated cyclic adenosine monophosphate production by polyvalent cations in MC3T3-E1 osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(6):789-99.
1995: S R Siddhanti; J E Hartle; L Darryl Quarles
Forskolin inhibits protein kinase C-induced mitogen activated protein kinase activity in MC3T3-E1 osteoblasts.
Endocrinology 1995;136(11):4834-41.
1995: Kathryn M Thrailkill; S R Siddhanti; John L Fowlkes; L Darryl Quarles
Differentiation of MC3T3-E1 osteoblasts is associated with temporal changes in the expression of IGF-I and IGFBPs.
Bone 1995;17(3):307-13.
1995: Kathryn M Thrailkill; L Darryl Quarles; H Nagase; K Suzuki; Delila M Serra; John L Fowlkes
Characterization of insulin-like growth factor-binding protein 5-degrading proteases produced throughout murine osteoblast differentiation.
Endocrinology 1995;136(8):3527-33.
1995: Olafur S Indridason; L Darryl Quarles
Oral versus intravenous calcitriol: is the route of administration really important?
Current opinion in nephrology and hypertension 1995;4(4):307-12.
1994: L Darryl Quarles; J E Hartle; J P Middleton; J Zhang; John M Arthur; John R Raymond
Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism.
Journal of cellular biochemistry 1994;56(1):106-17.
1994: S R Siddhanti; L Darryl Quarles
Molecular to pharmacologic control of osteoblast proliferation and differentiation.
Journal of cellular biochemistry 1994;55(3):310-20.
1994: L Darryl Quarles; D A Yohay; B A Carroll; C E Spritzer; S A Minda; D Bartholomay; B A Lobaugh
Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD.
Kidney international 1994;45(6):1710-21.
1994: D A Yohay; J Zhang; Kathryn M Thrailkill; John M Arthur; L Darryl Quarles
Role of serum in the developmental expression of alkaline phosphatase in MC3T3-E1 osteoblasts.
Journal of cellular physiology 1994;158(3):467-75.
1993: Kenneth W Lyles; Thomas Jackson; T Nesbitt; L Darryl Quarles
Salmon calcitonin reduces vertebral bone loss in glucocorticoid-treated beagles.
The American journal of physiology 1993;264(6 Pt 1):E938-42.
1993: K N Malizos; L Darryl Quarles; Anthony V Seaber; W S Rizk; James R Urbaniak
An experimental canine model of osteonecrosis: characterization of the repair process.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1993;11(3):350-7.
1993: L Darryl Quarles; D M Haupt; G Davidai; J P Middleton
Prostaglandin F2 alpha-induced mitogenesis in MC3T3-E1 osteoblasts: role of protein kinase-C-mediated tyrosine phosphorylation.
Endocrinology 1993;132(4):1505-13.
1993: R J Wenstrup; L W Lever; C L Phillips; L Darryl Quarles
Mutations in the COL1A2 gene of type I collagen that result in nonlethal forms of osteogenesis imperfecta.
American journal of medical genetics 1993;45(2):228-32.
1992: D A Yohay; David W Butterly; Steve J Schwab; L Darryl Quarles
Continuous arteriovenous hemodialysis: effect of dialyzer geometry.
Kidney international 1992;42(2):448-51.
1992: L Darryl Quarles
Prednisone-induced osteopenia in beagles: variable effects mediated by differential suppression of bone formation.
The American journal of physiology 1992;263(1 Pt 1):E136-41.
1992: L Darryl Quarles; B Lobaugh; G Murphy
Intact parathyroid hormone overestimates the presence and severity of parathyroid-mediated osseous abnormalities in uremia.
The Journal of clinical endocrinology and metabolism 1992;75(1):145-50.
1992: L Darryl Quarles; Marc K Drezner
Effects of etidronate-mediated suppression of bone remodeling on aluminum-induced de novo bone formation.
Endocrinology 1992;131(1):122-6.
1992: L Darryl Quarles; D A Yohay; L W Lever; R Caton; R J Wenstrup
Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: an in vitro model of osteoblast development.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(6):683-92.
1991: L Darryl Quarles; G Murphy; Michael J Econs; Salutario Martinez; B Lobaugh; Kenneth W Lyles
Uremic tumoral calcinosis: preliminary observations suggesting an association with aberrant vitamin D homeostasis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1991;18(6):706-10.
1991: C L Phillips; L W Lever; S R Pinnell; L Darryl Quarles; R J Wenstrup
Construction of a full-length murine pro alpha 2(I) collagen cDNA by the polymerase chain reaction.
The Journal of investigative dermatology 1991;97(6):980-4.
1991: Kevin P Speer; L Darryl Quarles; John M Harrelson; James A Nunley
Tetracycline labeling of the femoral head following acute intracapsular fracture of the femoral neck.
Clinical orthopaedics and related research 1991;(267):224-7.
1991: L Darryl Quarles; R J Wenstrup; S A Castillo; Marc K Drezner
Aluminum-induced mitogenesis in MC3T3-E1 osteoblasts: potential mechanism underlying neoosteogenesis.
Endocrinology 1991;128(6):3144-51.
1991: Michael J Econs; John R. Feussner; G P Samsa; E L Effman; J B Vogler; Salutario Martinez; N E Friedman; L Darryl Quarles; Marc K Drezner
X-linked hypophosphatemic rickets without "rickets".
Skeletal radiology 1991;20(2):109-14.
1991: L Darryl Quarles
Paradoxical toxic and trophic osseous actions of aluminum: potential explanations.
Mineral and electrolyte metabolism 1991;17(4):233-9.
1990: L Darryl Quarles; G Murphy; J B Vogler; Marc K Drezner
Aluminum-induced neo-osteogenesis: a generalized process affecting trabecular networking in the axial skeleton.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(6):625-35.
1990: L Darryl Quarles
Attenuated bone aluminum deposition in nonuremic beagles with reduced bone remodeling.
The American journal of physiology 1990;258(4 Pt 1):E576-81.
1989: L Darryl Quarles; B Lobaugh
Equivalency of various methods for estimating osteoid seam width.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1989;4(5):671-7.
1989: L Darryl Quarles; H J Gitelman; Marc K Drezner
Aluminum-induced de novo bone formation in the beagle. A parathyroid hormone-dependent event.
The Journal of clinical investigation 1989;83(5):1644-50.
1988: L Darryl Quarles; G A Davidai; Steve J Schwab; D W Bartholomay; B Lobaugh
Oral calcitriol and calcium: efficient therapy for uremic hyperparathyroidism.
Kidney international 1988;34(6):840-4.
1988: Steve J Schwab; L Darryl Quarles; J P Middleton; Richard H Cohan; M Saeed; V W Dennis
Hemodialysis-associated subclavian vein stenosis.
Kidney international 1988;33(6):1156-9.
1988: L Darryl Quarles; H J Gitelman; Marc K Drezner
Induction of de novo bone formation in the beagle. A novel effect of aluminum.
The Journal of clinical investigation 1988;81(4):1056-66.
1986: L Darryl Quarles; H J Gitelman; Marc K Drezner
Aluminum-associated bone disease: what's in a name?
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(5):389-90.
1986: G F Fant; V W Dennis; L Darryl Quarles
Late vascular complications of the subclavian dialysis catheter.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1986;7(3):225-8.
1986: L Darryl Quarles; H J Gitelman; Marc K Drezner
Aluminum: culprit or accessory in the genesis of renal osteodystrophy.
Seminars in nephrology 1986;6(1):90-101.
1985: L Darryl Quarles; V W Dennis; H J Gitelman; J M Harrelson; Marc K Drezner
Aluminum deposition at the osteoid-bone interface. An epiphenomenon of the osteomalacic state in vitamin D-deficient dogs.
The Journal of clinical investigation 1985;75(5):1441-7.