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Philip Raake

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Philip Raake; Julia Reinkober; Stefanie Schinkel; Philipp Schlegel; Sven T Pleger; Jens Barthelmes; Uwe Haberkorn; Hugo A Katus; Walter J Koch; Jan Ksienzyk; Walter Mier; Patrick Most; Oliver J Müller
AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model.
H A Katus; Philip Raake; Erland Erdmann
[Cardiomyopathies - heart failure: new concepts].
Patrick Most; Philip Raake; Christophe Weber; Hugo A Katus; Sven T Pleger
S100A1 gene therapy in small and large animals.

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All Publications

2013: Philip Raake; Julia Reinkober; Stefanie Schinkel; Philipp Schlegel; Sven T Pleger; Jens Barthelmes; Uwe Haberkorn; Hugo A Katus; Walter J Koch; Jan Ksienzyk; Walter Mier; Patrick Most; Oliver J Müller
AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model.
European heart journal 2013;34(19):1437-47.
2013: H A Katus; Philip Raake; Erland Erdmann
[Cardiomyopathies - heart failure: new concepts].
Deutsche medizinische Wochenschrift (1946) 2013;138(12):569.
2013: Patrick Most; Philip Raake; Christophe Weber; Hugo A Katus; Sven T Pleger
S100A1 gene therapy in small and large animals.
Methods in molecular biology (Clifton, N.J.) 2013;963():407-20.
2012: J Reinkober; H Tscheschner; Hugo A Katus; Walter J Koch; Patrick Most; Sven T Pleger; Philip Raake
Targeting GRK2 by gene therapy for heart failure: benefits above β-blockade.
Gene therapy 2012;19(6):686-93.
2012: Philip Raake; Mingxin Tang; Leif Erik Vinge; Xiaoying Zhang; Yingxin Li; Patrick Most; Henriette Brinks; Xiongwen Chen; Gerald W Dorn; Erhe Gao; Steven R Houser; Naser Jaleel; Hugo A Katus; Walter J Koch
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.
Circulation 2012;125(17):2108-18.
2011: Philip Raake; J Reinkober; J Ritterhoff; H Tscheschner; Hugo A Katus; Walter J Koch; Patrick Most
Gene therapy targets in heart failure: the path to translation.
Clinical pharmacology and therapeutics 2011;90(4):542-53.
2011: Sven T Pleger; Gang Qiu; Philip Raake; Stefanie Schinkel; Changguang Shan; Christophe Weber; Oliver J Müller; Raffi Bekeredjian; Peter Boekstegers; Rabea Hinkel; Hugo A Katus; Walter J Koch; Jan Ksienzyk; Barbara Leuchs; Jochen Ludwig; Patrick Most
Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model.
Science translational medicine 2011;3(92):92ra64.
2010: Raphael E Bonita; Philip Raake; Nicholas J Otis; J Kurt Chuprun; Talya Spivack; Abhijit Dasgupta; David Whellan; Paul J Mather; Walter J Koch
Dynamic changes in lymphocyte GRK2 levels in cardiac transplant patients: a biomarker for left ventricular function.
Clinical and translational science 2010;3(1):14-8.
2008: Jeffrey S Martini; Philip Raake; Leif Erik Vinge; Brent R DeGeorge; Brent DeGeorge; J Kurt Chuprun; David M Harris; Erhe Gao; Andrea D Eckhart; Julie A Pitcher; Walter J Koch
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12457-62.
2008: Philip Raake; Rabea Hinkel; S Müller; S Delker; R Kreuzpointner; Christian Kupatt; H A Katus; Jürgen A Kleinschmidt; Peter Boekstegers; O J Müller
Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors.
Gene therapy 2008;15(1):12-7.
2007: Christian Kupatt; Rabea Hinkel; Marie-Luise von Brühl; Tilmann Pohl; Jan Horstkotte; Philip Raake; Chiraz El Aouni; Eckart Thein; Stefanie Dimmeler; Olivier Feron; Peter Boekstegers
Endothelial nitric oxide synthase overexpression provides a functionally relevant angiogenic switch in hibernating pig myocardium.
Journal of the American College of Cardiology 2007;49(14):1575-84.
2005: Achim Pfosser; Philip Raake; C Reithmann; Jürgen Behr; Gerhard Steinbeck
[Unusual infection with pulmonary round foci obtained through "hay packs"].
Der Internist 2005;46(10):1152-7.
2005: Peter Boekstegers; Philip Raake; Rabea Hinkel; Tilmann Pohl; Christian Kupatt; Andreas Knez; Frank Christ; Sandra Eifert; Gerhard Steinbeck; Bruno Reichart; Calin Vicol
Hemodynamic and vascular effects of ventricular sourcing by stent-based ventricle to coronary artery bypass in patients with multivessel disease undergoing coronary artery bypass surgery.
Circulation 2005;112(9 Suppl):I304-10.
2005: Philip Raake; Rabea Hinkel; Christian Kupatt; Marie-Luise von Brühl; Sabrina Beller; Martin Andrees; Calin Vicol; Peter Boekstegers
Percutaneous approach to a stent-based ventricle to coronary vein bypass (venous VPASS): comparison to catheter-based selective pressure-regulated retro-infusion of the coronary vein.
European heart journal 2005;26(12):1228-34.
2005: Calin Vicol; Bruno Reichart; Sandra Eifert; Philip Raake; Rabea Hinkel; Gerhard Steinbeck; Peter Boekstegers
First clinical experience with the VSTENT: a device for direct left ventricle-to-coronary artery bypass.
The Annals of thoracic surgery 2005;79(2):573-9; discussion 579.
2004: Philip Raake; Georges von Degenfeld; Rabea Hinkel; Robert Vachenauer; Torleif Sandner; Sabrina Beller; Martin Andrees; Christian Kupatt; Gerhard Schuler; Peter Boekstegers
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins: comparison with surgical and percutaneous intramyocardial gene delivery.
Journal of the American College of Cardiology 2004;44(5):1124-9.
2004: Christian Kupatt; Chantal Dessy; Rabea Hinkel; Philip Raake; Géraldine Daneau; Caroline Bouzin; Peter Boekstegers; Olivier Feron
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(8):1435-41.
2004: Tilmann Pohl; Wolfgang Giehrl; Bruno Reichart; Christian Kupatt; Philip Raake; Stefan Paul; Hermann Reichenspurner; Gerhard Steinbeck; Peter Boekstegers
Retroinfusion-supported stenting in high-risk patients for percutaneous intervention and bypass surgery: results of the prospective randomized myoprotect I study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2004;62(3):323-30.
2003: Georges von Degenfeld; Philip Raake; Christian Kupatt; Corinna Lebherz; Rabea Hinkel; Franz-Josef Gildehaus; Wolfgang Münzing; Andrea Kranz; Johannes Waltenberger; Marcus V Simoes; Markus Schwaiger; Eckart Thein; Peter Boekstegers
Selective pressure-regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia.
Journal of the American College of Cardiology 2003;42(6):1120-8.
2003: Rembert Koczulla; Georges von Degenfeld; Christian Kupatt; Florian Krötz; Stefan Zahler; Torsten Gloe; Katja Issbrücker; Pia Unterberger; Mohamed Zaiou; Corinna Lebherz; Alexander Karl; Philip Raake; Achim Pfosser; Peter Boekstegers; Ulrich Welsch; Pieter S Hiemstra; Claus Vogelmeier; Richard L Gallo; Matthias Clauss; Robert Bals
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.
The Journal of clinical investigation 2003;111(11):1665-72.
2003: Christian Kupatt; Rabea Hinkel; Robert Vachenauer; Jan Horstkotte; Philip Raake; Torleif Sandner; Robert Kreuzpointner; Fabian Müller; Stefanie Dimmeler; Olivier Feron; Peter Boekstegers
VEGF165 transfection decreases postischemic NF-kappa B-dependent myocardial reperfusion injury in vivo: role of eNOS phosphorylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):705-7.
2003: Corinna Lebherz; Georges von Degenfeld; Alexander Karl; Achim Pfosser; Philip Raake; Florian Pachmayr; Dimitri Scholz; Christian Kupatt; Peter Boekstegers
Therapeutic angiogenesis/arteriogenesis in the chronic ischemic rabbit hindlimb: effect of venous basic fibroblast growth factor retroinfusion.
Endothelium : journal of endothelial cell research 2003;10(4-5):257-65.
2002: Peter Boekstegers; Philip Raake; Rasul Al Ghobainy; Jan Horstkotte; Rabea Hinkel; Torleif Sandner; Reinhard Wichels; Franz Meisner; Eckart Thein; Keith March; Dieter Boehm; Hermann Reichenspurner
Stent-based approach for ventricle-to-coronary artery bypass.
Circulation 2002;106(8):1000-6.
2002: Christian Kupatt; Reinhard Wichels; M Deiss; Alexander Molnar; Corinna Lebherz; Philip Raake; Georges von Degenfeld; D Hahnel; Peter Boekstegers
Retroinfusion of NFkappaB decoy oligonucleotide extends cardioprotection achieved by CD18 inhibition in a preclinical study of myocardial ischemia and retroinfusion in pigs.
Gene therapy 2002;9(8):518-26.