FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Stuart Bevan

Research Profile

Living Beings

Disorders

Chemicals & Drugs

Anatomy

Concepts & Ideas

Co-author Network

Publications

TOP 3
Mark S Nash; Moh Panesar; Andrew J Culshaw; Alyson Fox; Alex Groarke; Allan Hallett; Elliot Lilley; Peter McIntyre; Stuart Bevan
7-tert-Butyl-6-(4-chloro-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one, a classic polymodal inhibitor of transient receptor potential vanilloid type 1 with a reduced liability for hyperthermia, is analgesic and ameliorates visceral hypersensitivity.
David A Andersson; Clive Gentry; Stuart Bevan
TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.
Rabea Graepel; Elizabeth S Fernandes; Aisah A Aubdool; David A Andersson; Stuart Bevan; Susan D Brain
4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Stuart Bevan (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Mark S Nash; Moh Panesar; Andrew J Culshaw; Alyson Fox; Alex Groarke; Allan Hallett; Elliot Lilley; Peter McIntyre; Stuart Bevan
7-tert-Butyl-6-(4-chloro-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one, a classic polymodal inhibitor of transient receptor potential vanilloid type 1 with a reduced liability for hyperthermia, is analgesic and ameliorates visceral hypersensitivity.
The Journal of pharmacology and experimental therapeutics 2012;342(2):389-98.
2012: David A Andersson; Clive Gentry; Stuart Bevan
TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.
PloS one 2012;7(10):e46917.
2011: Rabea Graepel; Elizabeth S Fernandes; Aisah A Aubdool; David A Andersson; Stuart Bevan; Susan D Brain
4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo.
The Journal of pharmacology and experimental therapeutics 2011;337(1):117-24.
2011: Elizabeth S Fernandes; Fiona A Russell; Domenico Spina; Jason J McDougall; Rabea Graepel; Clive Gentry; Amelia A Staniland; David M Mountford; Julie Keeble; Marzia Malcangio; Stuart Bevan; Susan D Brain
A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis.
Arthritis and rheumatism 2011;63(3):819-29.
2011: David A Andersson; Stuart Bevan; Bernard Bucher; jean luc galzi; Clive Gentry; Edward D Högestätt; Dan Killander; Simon E Lewis; Olov Sterner; Lisa Alenmyr; Anders Andersson; Peter M Zygmunt
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.
Nature communications 2011;2():551.
2010: Gabor Pozsgai; Jennifer V Bodkin; Rabea Graepel; Stuart Bevan; David A Andersson; Susan D Brain
Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo.
Cardiovascular research 2010;87(4):760-8.
2010: Clive Gentry; Natalie Stoakley; David A Andersson; Stuart Bevan
The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity.
Molecular pain 2010;6():4.
2009: Stuart Bevan; David A Andersson
TRP channel antagonists for pain--opportunities beyond TRPV1.
Current opinion in investigational drugs (London, England : 2000) 2009;10(7):655-63.
2009: David A Andersson; Clive Gentry; Sian Moss; Stuart Bevan
Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(20):8374-9.
2008: Osamu Irie; Takatoshi Kosaka; Takeru Ehara; Fumiaki Yokokawa; Takanori Kanazawa; Hajime Hirao; Astuko Iwasaki; Junichi Sakaki; Naoki Teno; Yuko Hitomi; Genji Iwasaki; Hiroaki Fukaya; Kazuhiko Nonomura; Keiko Tanabe; Shinichi Koizumi; Noriko Uchiyama; Stuart Bevan; Marzia Malcangio; Clive Gentry; Alyson J Fox; Mohammed Yaqoob; Andrew J Culshaw
Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain.
Journal of medicinal chemistry 2008;51(18):5502-5.
2008: David A Andersson; Clive Gentry; Sian Moss; Stuart Bevan
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(10):2485-94.
2008: Tomi Streng; Helena E Axelsson; Petter Hedlund; David A Andersson; Sven-Eric Jordt; Stuart Bevan; Karl-Erik Andersson; Edward D Högestätt; Peter M Zygmunt
Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.
European urology 2008;53(2):391-9.
2007: Edward K Dziadulewicz; Stuart Bevan; Christopher T Brain; Paul R Coote; Andrew J Culshaw; Andrew J Davis; Lee J Edwards; Adrian J Fisher; Alyson J Fox; Clive Gentry; Alex Groarke; Terance W Hart; Werner Huber; Iain F James; Adam Kesingland; Luigi La Vecchia; Yvonne Loong; Isabelle Lyothier; Kara McNair; Cathal O'Farrell; Marcus Peacock; Robert Portmann; Ulrich Schopfer; Mohammed Yaqoob; Jiri Zadrobilek
Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration.
Journal of medicinal chemistry 2007;50(16):3851-6.
2007: Jane Barclay; Anna K Clark; Pam Ganju; Clive Gentry; Sadhana Patel; Glen Wotherspoon; Frank Buxton; Chuanzheng Song; Jakir Ullah; Janet Winter; Alyson Fox; Stuart Bevan; Marzia Malcangio
Role of the cysteine protease cathepsin S in neuropathic hyperalgesia.
Pain 2007;130(3):225-34.
2007: Anna K Clark; Ping K Yip; John Grist; Clive Gentry; Amelia A Staniland; Fabien Marchand; Maliheh Dehvari; Glen Wotherspoon; Janet Winter; Jakir Ullah; Stuart Bevan; Marzia Malcangio
Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10655-60.
2007: David A Andersson; Mark Nash; Stuart Bevan
Modulation of the cold-activated channel TRPM8 by lysophospholipids and polyunsaturated fatty acids.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(12):3347-55.
2006: Andrew J Culshaw; Stuart Bevan; Martin Christiansen; Prafula Copp; Andrew Davis; Clare Davis; Alex Dyson; Edward K Dziadulewicz; Lee Edwards; Hendrikus Eggelte; Alyson Fox; Clive Gentry; Alex Groarke; Allan Hallett; Terance W Hart; Glyn A Hughes; Sally Knights; Peter Kotsonis; Wai Lee; Isabelle Lyothier; Andrew McBryde; Peter McIntyre; George Paloumbis; Moh Panesar; Sadhana Patel; Max-Peter Seiler; Mohammed Yaqoob; Kaspar Zimmermann
Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain.
Journal of medicinal chemistry 2006;49(2):471-4.
2005: Janet Fernihough; Clive Gentry; Stuart Bevan; Janet Winter
Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis.
Neuroscience letters 2005;388(2):75-80.
2005: Alyson Fox; Stuart Bevan
Therapeutic potential of cannabinoid receptor agonists as analgesic agents.
Expert opinion on investigational drugs 2005;14(6):695-703.
2005: Alyson Fox; Satbir Kaur; Bifang Li; Moh Panesar; Uma Saha; Clare Davis; Ilaria Dragoni; Sian Colley; Tim Ritchie; Stuart Bevan; Gillian Burgess; Peter McIntyre
Antihyperalgesic activity of a novel nonpeptide bradykinin B1 receptor antagonist in transgenic mice expressing the human B1 receptor.
British journal of pharmacology 2005;144(7):889-99.
2005: Glen Wotherspoon; Alyson Fox; Peter McIntyre; Sian Colley; Stuart Bevan; Janet Winter
Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons.
Neuroscience 2005;135(1):235-45.
2004: Janet Fernihough; Clive Gentry; Marzia Malcangio; Alyson Fox; John Rediske; Ted Pellas; Bruce L Kidd; Stuart Bevan; Janet Winter
Pain related behaviour in two models of osteoarthritis in the rat knee.
Pain 2004;112(1-2):83-93.
2004: Timothy John Ritchie; Edward K Dziadulewicz; Andrew J Culshaw; Werner Müller; Gillian M Burgess; Graham C Bloomfield; Gillian S Drake; Andrew R Dunstan; David Beattie; Glyn A Hughes; Pam Ganju; Peter McIntyre; Stuart Bevan; Clare Davis; Mohammed Yaqoob
Potent and orally bioavailable non-peptide antagonists at the human bradykinin B(1) receptor based on a 2-alkylamino-5-sulfamoylbenzamide core.
Journal of medicinal chemistry 2004;47(19):4642-4.
2004: David A Andersson; Henry W N Chase; Stuart Bevan
TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(23):5364-9.
2004: Gabriele Dorn; Sadhana Patel; Glen Wotherspoon; Maja Hemmings-Mieszczak; Jane Barclay; Francois Natt; Pierre Martin; Stuart Bevan; Alyson Fox; Pam Ganju; William L Wishart; Jonathan Hall
siRNA relieves chronic neuropathic pain.
Nucleic acids research 2004;32(5):e49.
2004: Alyson Fox; Stephen J Medhurst; Jean-Philippe Courade; Markus Glatt; Janet Dawson; Laszlo Urban; Stuart Bevan; Isabel Gonzalez
Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.
Pain 2004;107(1-2):33-40.
2003: Alyson Fox; Clive Gentry; Sadhana Patel; Adam Kesingland; Stuart Bevan
Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig.
Pain 2003;105(1-2):355-62.
2003: Gina M Story; Andrea M Peier; Alison J Reeve; Samer R Eid; Johannes Mosbacher; Todd R Hricik; Taryn J Earley; Anne C Hergarden; David A Andersson; Sun Wook Hwang; Peter McIntyre; Tim Jegla; Stuart Bevan; Ardem Patapoutian
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Cell 2003;112(6):819-29.
2002: Nina Storey; David S Latchman; Stuart Bevan
Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1.
The Journal of cell biology 2002;158(7):1251-62.
2002: Jane Barclay; Sadhana Patel; Gabriele Dorn; Glen Wotherspoon; Sarah Moffatt; Louise H Eunson; Samir Abdel'al; Francois Natt; Jonathan Hall; Janet Winter; Stuart Bevan; William L Wishart; Alyson Fox; Pam Ganju
Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(18):8139-47.
2002: Andrea M Peier; Alison J Reeve; David A Andersson; Aziz Moqrich; Taryn J Earley; Anne C Hergarden; Gina M Story; Sian Colley; John B Hogenesch; Peter McIntyre; Stuart Bevan; Ardem Patapoutian
A heat-sensitive TRP channel expressed in keratinocytes.
Science (New York, N.Y.) 2002;296(5575):2046-9.
2002: Lindsey J Hudson; Stuart Bevan; Kara McNair; Clive Gentry; Alyson Fox; Rainer Kuhn; Janet Winter
Metabotropic glutamate receptor 5 upregulation in A-fibers after spinal nerve injury: 2-methyl-6-(phenylethynyl)-pyridine (MPEP) reverses the induced thermal hyperalgesia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2660-8.
2002: Andrea M Peier; Aziz Moqrich; Anne C Hergarden; Alison J Reeve; David A Andersson; Gina M Story; Taryn J Earley; Ilaria Dragoni; Peter McIntyre; Stuart Bevan; Ardem Patapoutian
A TRP channel that senses cold stimuli and menthol.
Cell 2002;108(5):705-15.
2002: Stuart Bevan; Nina Storey
Modulation of sodium channels in primary afferent neurons.
Novartis Foundation symposium 2002;241():144-53; discussion 153-8, 226-32.
2001: L J Hudson; Stuart Bevan; Glen Wotherspoon; Clive Gentry; Alyson Fox; Janet Winter
VR1 protein expression increases in undamaged DRG neurons after partial nerve injury.
The European journal of neuroscience 2001;13(11):2105-14.
2001: Peter McIntyre; LM McLatchie; A Chambers; Elsa Phillips; M Clarke; Jonathan Savidge; C Toms; Marcus Peacock; K Shah; Janet Winter; N Weerasakera; M Webb; Humphrey P Rang; Stuart Bevan; Iain F James
Pharmacological differences between the human and rat vanilloid receptor 1 (VR1).
British journal of pharmacology 2001;132(5):1084-94.
2001: LM McLatchie; Stuart Bevan
The effects of pH on the interaction between capsaicin and the vanilloid receptor in rat dorsal root ganglia neurons.
British journal of pharmacology 2001;132(4):899-908.
1999: AS Piper; J C Yeats; Stuart Bevan; Reginald J Docherty
A study of the voltage dependence of capsaicin-activated membrane currents in rat sensory neurones before and after acute desensitization.
The Journal of physiology 1999;518 ( Pt 3)():721-33.
1999: C Jones; Elsa Phillips; Clare Davis; J Arbuckle; Mohammed Yaqoob; Gillian M Burgess; Reginald J Docherty; M Webb; Stuart Bevan; Peter McIntyre
Molecular characterisation of cloned bradykinin B1 receptors from rat and human.
European journal of pharmacology 1999;374(3):423-33.
1998: R J Helliwell; LM McLatchie; M Clarke; Janet Winter; Stuart Bevan; Peter McIntyre
Capsaicin sensitivity is associated with the expression of the vanilloid (capsaicin) receptor (VR1) mRNA in adult rat sensory ganglia.
Neuroscience letters 1998;250(3):177-80.