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Gabriel Rabinovich

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Ada G Blidner; Gabriel A Rabinovich
'Sweetening' pregnancy: galectins at the fetomaternal interface.
Ethelina Cargnelutti; Gabriel A Rabinovich; Susana R Valdez; José L Arias; María S Di Genaro
TNFRp55 controls regulatory T cell responses in Yersinia-induced reactive arthritis.
Tomás Dalotto-Moreno; Sebastián Dergan-Dylon; Verónica C Martinez-Allo; Daniel Mazal; Santiago P Méndez-Huergo; Eduardo Osinaga; Gabriel A Rabinovich; Juan P Cerliani; Diego O Croci; Juan C Stupirski; Victoria Sundblad; Marta A Toscano; Mariana Salatino
Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease.

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All Publications

2013: Ada G Blidner; Gabriel A Rabinovich
'Sweetening' pregnancy: galectins at the fetomaternal interface.
American journal of reproductive immunology (New York, N.Y. : 1989) 2013;69(4):369-82.
2013: Ethelina Cargnelutti; Gabriel A Rabinovich; Susana R Valdez; José L Arias; María S Di Genaro
TNFRp55 controls regulatory T cell responses in Yersinia-induced reactive arthritis.
Immunology and cell biology 2013;91(2):159-66.
2013: Tomás Dalotto-Moreno; Sebastián Dergan-Dylon; Verónica C Martinez-Allo; Daniel Mazal; Santiago P Méndez-Huergo; Eduardo Osinaga; Gabriel A Rabinovich; Juan P Cerliani; Diego O Croci; Juan C Stupirski; Victoria Sundblad; Marta A Toscano; Mariana Salatino
Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease.
Cancer research 2013;73(3):1107-17.
2013: Diego J Laderach; Osvaldo Néstor Mazza; Lorena Nugnes; Scott J Rodig; Paula A Sacca; Margaret A Shipp; Elba Vazquez; Nader Al Nakouzi; Gabriel Casas; Anne Chauchereau; Daniel Compagno; Diego O Croci; Victor Cardenas Delgado; María T Elola; Lucas D Gentilini; Laura Giribaldi; Jeffery L Kutok; Gabriel A Rabinovich
A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease.
Cancer research 2013;73(1):86-96.
2012: Diego O Croci; María C Croci; Carolina I Domaica; Juan M Ilarregui; Howard J Leung; Enrique Mesri; Jing Ouyang; Natalia Rubinstein; Mariana Salatino; Margaret A Shipp; Marta A Toscano; Adriana Albini; Lucas E Cavallin; Juan P Cerliani; Gabriel A Rabinovich
Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma.
The Journal of experimental medicine 2012;209(11):1985-2000.
2012: Rosanna Ramhorst; Marta D Romero; Natalia Rubinstein; Peter Sedlmayr; Juan C Stupirski; Marta A Toscano; Astrid Blaschitz; Edith S Durand; Leonardo Fainboim; Laura Fraccaroli; Susana Genti-Raimondi; Laura Giribaldi; Gabriel A Rabinovich
Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.
Glycobiology 2012;22(10):1374-86.
2012: Sarah C Starossom; Yue Wang; Khadir Raddassi; Ribal Bassil; Li Cao; Juan P Cerliani; Diego O Croci; Delphine Delacour; Wassim Elyaman; Silvia F Hernandez; Jaime Imitola; Samia J Khoury; Ivan D Mascanfroni; Gabriel A Rabinovich
Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration.
Immunity 2012;37(2):249-63.
2012: Marta Toscano; J Brian de Souza; Fu-Tong Liu; Eleanor M Riley; Jon Eric Tongren; Gabriel A Rabinovich
Endogenous galectin-3 controls experimental malaria in a species-specific manner.
Parasite immunology 2012;34(7):383-7.
2012: Maria Romaniuk; Maria V Tribulatti; Oscar Campetella; Diego O Croci; Maria J Lapponi; Soledad Negrotto; Françoise Poirier; Gabriel A Rabinovich; Mirta Schattner
Binding of galectin-1 to αIIbβ₃ integrin triggers "outside-in" signals, stimulates platelet activation, and controls primary hemostasis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(7):2788-98.
2012: Gabriel A Rabinovich; Yvette van Kooyk; Brian A Cobb
Glycobiology of immune responses.
Annals of the New York Academy of Sciences 2012;1253():1-15.
2012: Mariano F Zacarias Fluck; Juan C Stupirski; Diego O Croci; RJ Di Masso; Leonardo Hess; Gabriel A Rabinovich; Eduardo Roggero; Mariana Salatino; O Graciela Scharovsky
The aggressiveness of murine lymphomas selected in vivo by growth rate correlates with galectin-1 expression and response to cyclophosphamide.
Cancer immunology, immunotherapy : CII 2012;61(4):469-80.
2012: Gabriel A Rabinovich; Diego O Croci
Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer.
Immunity 2012;36(3):322-35.
2012: Lucas E Rossi; Raúl Spallanzani; Andrea Ziblat; Damián E Avila; Diego O Croci; Carolina I Domaica; Mercedes B Fuertes; Lara Lapyckyj; Gabriel A Rabinovich; Norberto Zwirner
Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression.
Journal of leukocyte biology 2012;91(2):321-31.
2011: Ricardo J Eliçabe; Gabriel A Rabinovich; José L Arias; María S Di Genaro
TNFRp55 modulates IL-6 and nitric oxide responses following Yersinia lipopolysaccharide stimulation in peritoneal macrophages.
Immunobiology 2011;216(12):1322-30.
2011: Roberto C Davicino; María S Di Genaro; Ricardo J Eliçabe; Gabriel A Rabinovich
Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms.
International immunopharmacology 2011;11(10):1457-63.
2011: Marta A Toscano; Norberto Zwirner; Leonardo Campagna; Juan P Cerliani; Mónica A Costas; Diego O Croci; Juan P Fededa; Mercedes B Fuertes; Juan M Ilarregui; Luciana L Molinero; Ignacio M Nojek; Gabriel A Rabinovich
Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1.
Molecular immunology 2011;48(15-16):1940-9.
2011: Carlos M A Guardia; Marcelo A Martí; Gabriel A Rabinovich; Santiago Di Lella; Diego F Gauto; Darío A Estrin
An integrated computational analysis of the structure, dynamics, and ligand binding interactions of the human galectin network.
Journal of chemical information and modeling 2011;51(8):1918-30.
2011: Maria Romaniuk; Oscar Campetella; Soledad Negrotto; Gabriel A Rabinovich; Mirta Schattner
Identification of galectins as novel regulators of platelet signaling and function.
IUBMB life 2011;63(7):521-7.
2011: Iván D Mascanfroni; Juan P Cerliani; Sebastián Dergan-Dylon; Diego O Croci; Juan M Ilarregui; Gabriel A Rabinovich
Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: mechanisms and biomedical applications.
International immunopharmacology 2011;11(7):833-41.
2011: Diego J Laderach; Susana A Pesoa; Daniel Compagno; Gabriel A Rabinovich
TSLP1: a new piece in the puzzle of tumor-associated Th2-type inflammation.
Immunotherapy 2011;3(6):713-7.
2011: Cristina A Maldonado; Victoria Sundblad; Mariana Salatino; Jorge Elia; Luciana N García; Carolina Leimgruber; Diego O Croci; Gabriel A Rabinovich
Cell-type specific regulation of galectin-3 expression by glucocorticoids in lung Clara cells and macrophages.
Histology and histopathology 2011;26(6):747-59.
2011: MV Espelt; Diego O Croci; María L Bacigalupo; Pablo Carabias; Malena Manzi; María T Elola; Marina C Muñoz; Fernando P Dominici; Carlota Wolfenstein-Todel; Gabriel A Rabinovich; María F Troncoso
Novel roles of galectin-1 in hepatocellular carcinoma cell adhesion, polarization, and in vivo tumor growth.
Hepatology (Baltimore, Md.) 2011;53(6):2097-106.
2011: Juan P Cerliani; Sean R Stowell; Iván D Mascanfroni; Connie M Arthur; Richard D Cummings; Gabriel A Rabinovich
Expanding the universe of cytokines and pattern recognition receptors: galectins and glycans in innate immunity.
Journal of clinical immunology 2011;31(1):10-21.
2011: Victoria Sundblad; Diego O Croci; Gabriel A Rabinovich
Regulated expression of galectin-3, a multifunctional glycan-binding protein, in haematopoietic and non-haematopoietic tissues.
Histology and histopathology 2011;26(2):247-65.
2011: Diego O Croci; Albana Cumashi; Natalia A Ushakova; Marina E Preobrazhenskaya; Antonio Piccoli; Licia Totani; Nadezhda E Ustyuzhanina; Maria I Bilan; Anatolii I Usov; Alexey A Grachev; Galina E Morozevich; Albert E Berman; Craig J Sanderson; Maeve Kelly; Patrizia Di Gregorio; Cosmo Rossi; Nicola Tinari; Stefano Iacobelli; Gabriel A Rabinovich; Nikolay E Nifantiev
Fucans, but not fucomannoglucuronans, determine the biological activities of sulfated polysaccharides from Laminaria saccharina brown seaweed.
PloS one 2011;6(2):e17283.
2011: Mariana Salatino; Gabriel A Rabinovich
Fine-tuning antitumor responses through the control of galectin-glycan interactions: an overview.
Methods in molecular biology (Clifton, N.J.) 2011;677():355-74.
2011: Víctor M Cárdenas Delgado; Lorena G Nugnes; Lucas L Colombo; María F Troncoso; Marisa Fernandez; Emilio L Malchiodi; Isabel Frahm; Diego O Croci; Daniel Compagno; Gabriel A Rabinovich; Carlota Wolfenstein-Todel; María T Elola
Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(1):242-54.
2010: Gabriel A Rabinovich
A sweet path toward tolerance in the gut.
Nature medicine 2010;16(10):1076-7.
2010: Santiago Di Lella; Marcelo A Martí; Diego O Croci; Carlos M A Guardia; Juan C Díaz-Ricci; Gabriel A Rabinovich; Julio J Caramelo; Darío A Estrin
Linking the structure and thermal stability of beta-galactoside-binding protein galectin-1 to ligand binding and dimerization equilibria.
Biochemistry 2010;49(35):7652-8.
2010: Iván D Mascanfroni; María del Mar Montesinos; Vanina A Alamino; Sebastián Susperreguy; Juan P Nicola; Juan M Ilarregui; Ana M Masini-Repiso; Gabriel A Rabinovich; Claudia G Pellizas
Nuclear factor (NF)-kappaB-dependent thyroid hormone receptor beta1 expression controls dendritic cell function via Akt signaling.
The Journal of biological chemistry 2010;285(13):9569-82.
2010: Dianne Cooper; Juan M Ilarregui; Susana A Pesoa; Diego O Croci; Mauro Perretti; Gabriel A Rabinovich
Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate.
Methods in enzymology 2010;480():199-244.
2010: Leandro P Casiraghi; Diego O Croci; Francoise Poirier; Gabriel A Rabinovich; Diego A Golombek
"Time sweet time": circadian characterization of galectin-1 null mice.
Journal of circadian rhythms 2010;8():4.
2010: Juan M Ilarregui; Gabriel A Rabinovich
Tolerogenic dendritic cells in the control of autoimmune neuroinflammation: an emerging role of protein-glycan interactions.
Neuroimmunomodulation 2010;17(3):157-60.
2010: Norberto Zwirner; Diego O Croci; Carolina I Domaica; Gabriel A Rabinovich
Overcoming the hurdles of tumor immunity by targeting regulatory pathways in innate and adaptive immune cells.
Current pharmaceutical design 2010;16(3):255-67.
2010: Diego J Laderach; Daniel Compagno; Marta Toscano; Diego O Croci; Sebastián Dergan-Dylon; Mariana Salatino; Gabriel A Rabinovich
Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings.
IUBMB life 2010;62(1):1-13.
2009: Juan M Ilarregui; Diego O Croci; German Ariel Bianco; Marta Toscano; Mariana Salatino; Mónica E Vermeulen; Jorge R Geffner; Gabriel A Rabinovich
Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10.
Nature immunology 2009;10(9):981-91.
2009: Carolina I Domaica; Mercedes B Fuertes; Lucas E Rossi; María V Girart; Damián E Avila; Gabriel A Rabinovich; Norberto W Zwirner
Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands.
EMBO reports 2009;10(8):908-15.
2009: Gabriel A Rabinovich; Juan M Ilarregui
Conveying glycan information into T-cell homeostatic programs: a challenging role for galectin-1 in inflammatory and tumor microenvironments.
Immunological reviews 2009;230(1):144-59.
2009: Gabriel A Rabinovich; Marta A Toscano
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation.
Nature reviews. Immunology 2009;9(5):338-52.
2009: Esteban Ciliberti; Leandro Carambia; Sebastian Cavallin; Osvaldo L Cerda; Juan J Poderoso; Gabriel A Rabinovich
[Tolerance and autoimmunity. Novel therapeutic approaches].
Medicina 2009;69(4):460-5.
2009: Ida Iurisci; Albana Cumashi; Andrei A Sherman; Yury E Tsvetkov; Nicola Tinari; Enza Piccolo; Maurizia D'Egidio; Vincenzo Adamo; Clara Natoli; Gabriel A Rabinovich; Stefano Iacobelli; Nikolay E Nifantiev
Synthetic inhibitors of galectin-1 and -3 selectively modulate homotypic cell aggregation and tumor cell apoptosis.
Anticancer research 2009;29(1):403-10.
2008: Gabriel A Rabinovich; Alexis M Kalergis; Norberto Zwirner; Wilson Savino
Immunology south of the equator in the Americas.
Nature immunology 2008;9(10):1087-90.
2008: Diego O Croci; Ingrid S Cogno; Natalia B Rumie Vittar; Edgardo Salvatierra; Felipe Trajtenberg; Osvaldo L Podhajcer; Eduardo Osinaga; Gabriel A Rabinovich; Viviana A Rivarola
Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway.
Journal of cellular biochemistry 2008;105(2):381-90.
2008: Mercedes B Fuertes; María Victoria Girart; Luciana L Molinero; Carolina I Domaica; Lucas E Rossi; María Marcela Barrio; José Mordoh; Gabriel A Rabinovich; Norberto Zwirner
Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4606-14.
2008: Ivan Mascanfroni; María del Mar Montesinos; Sebastián Susperreguy; Laura Cervi; Juan M Ilarregui; Vanesa D Ramseyer; Ana M Masini-Repiso; Héctor M Targovnik; Gabriel A Rabinovich; Claudia G Pellizas
Control of dendritic cell maturation and function by triiodothyronine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(4):1032-42.
2008: Natalia Pacienza; Roberto Gabriel Pozner; German Ariel Bianco; Lina P D'Atri; Diego O Croci; Soledad Negrotto; Elisa Malaver; Ricardo M Gómez; Gabriel A Rabinovich; Mirta Schattner
The immunoregulatory glycan-binding protein galectin-1 triggers human platelet activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(4):1113-23.
2008: Pablo N Fernández Larrosa; Diego O Croci; Diego A Riva; Mariel Bibini; Renata Luzzi; Mónica Saracco; Susana E Mersich; Gabriel A Rabinovich; Liliana Martínez Peralta
Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway.
Retrovirology 2008;5():19.
2008: Mariana Salatino; Diego O Croci; German Ariel Bianco; Juan M Ilarregui; Marta Toscano; Gabriel A Rabinovich
Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.
Expert opinion on biological therapy 2008;8(1):45-57.
2007: Sandra M Blois; Juan M Ilarregui; Mareike Tometten; Mariana Garcia; Arif S Orsal; Rosalia Cordo-Russo; Marta Toscano; German Ariel Bianco; Peter Kobelt; Bori Handjiski; Irene Tirado; Udo Markert; Burghard F Klapp; Françoise Poirier; Julia Szekeres-Bartho; Gabriel A Rabinovich; Petra C Arck
A pivotal role for galectin-1 in fetomaternal tolerance.
Nature medicine 2007;13(12):1450-7.
2007: Diego O Croci; Mariano F Zacarias Fluck; María J Rico; Pablo Matar; Gabriel A Rabinovich; O Graciela Scharovsky
Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment.
Cancer immunology, immunotherapy : CII 2007;56(11):1687-700.
2007: Gabriel A Rabinovich; Marta Toscano; Shawn S Jackson; Gerardo Vasta
Functions of cell surface galectin-glycoprotein lattices.
Current opinion in structural biology 2007;17(5):513-20.
2007: Marta Toscano; German Ariel Bianco; Juan M Ilarregui; Diego O Croci; Jorge Correale; Joseph D Hernandez; Norberto Zwirner; Françoise Poirier; Eleanor M Riley; Linda G Baum; Gabriel A Rabinovich
Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death.
Nature immunology 2007;8(8):825-34.
2007: M T Elola; Carlota Wolfenstein-Todel; María F Troncoso; Gerardo Vasta; Gabriel A Rabinovich
Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survival.
Cellular and molecular life sciences : CMLS 2007;64(13):1679-700.
2007: Nadja Tariverdian; Theoharis C Theoharides; Friederike Siedentopf; Gabriela Gutiérrez; Udo Jeschke; Gabriel A Rabinovich; Sandra M Blois; Petra C Arck
Neuroendocrine-immune disequilibrium and endometriosis: an interdisciplinary approach.
Seminars in immunopathology 2007;29(2):193-210.
2007: Albana Cumashi; Natalia A Ushakova; Marina E Preobrazhenskaya; Armida D'Incecco; Antonio Piccoli; Licia Totani; Nicola Tinari; Galina E Morozevich; Albert E Berman; Maria I Bilan; Anatolii I Usov; Nadezhda E Ustyuzhanina; Alexey A Grachev; Craig J Sanderson; Maeve Kelly; Gabriel A Rabinovich; Stefano Iacobelli; Nikolay E Nifantiev
A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds.
Glycobiology 2007;17(5):541-52.
2007: Cecilia M Daroqui; Juan M Ilarregui; Natalia Rubinstein; Mariana Salatino; Marta Toscano; Paula Vazquez; Andrei Bakin; Lydia Puricelli; Elisa Bal de Kier Joffé; Gabriel A Rabinovich
Regulation of galectin-1 expression by transforming growth factor beta1 in metastatic mammary adenocarcinoma cells: implications for tumor-immune escape.
Cancer immunology, immunotherapy : CII 2007;56(4):491-9.
2007: Gabriel A Rabinovich
Cytokines coming of age in South America.
Cytokine & growth factor reviews 2007;18(1-2):1-3.
2007: Marta Toscano; Juan M Ilarregui; German Ariel Bianco; Leonardo Campagna; Diego O Croci; Mariana Salatino; Gabriel A Rabinovich
Dissecting the pathophysiologic role of endogenous lectins: glycan-binding proteins with cytokine-like activity?
Cytokine & growth factor reviews 2007;18(1-2):57-71.
2007: Mariano F Zacarias Fluck; María J Rico; Silvia I Gervasoni; Juan M Ilarregui; Marta Toscano; Gabriel A Rabinovich; O Graciela Scharovsky
Low-dose cyclophosphamide modulates galectin-1 expression and function in an experimental rat lymphoma model.
Cancer immunology, immunotherapy : CII 2007;56(2):237-48.
2007: Paula Barrionuevo; Macarena Beigier-Bompadre; Juan M Ilarregui; Marta Toscano; German Ariel Bianco; Martín A Isturiz; Gabriel A Rabinovich
A novel function for galectin-1 at the crossroad of innate and adaptive immunity: galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(1):436-45.
2007: Gabriel A Rabinovich; Dmitry I Gabrilovich; Eduardo M Sotomayor
Immunosuppressive strategies that are mediated by tumor cells.
Annual review of immunology 2007;25():267-96.
2006: Marta Toscano; Alessandra G Commodaro; Juan M Ilarregui; German Ariel Bianco; Ana Liberman; Horacio Marcelo Serra; Jun Hirabayashi; Luiz Vicente Rizzo; Gabriel A Rabinovich
Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- and T regulatory-mediated anti-inflammatory responses.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):6323-32.
2006: German Ariel Bianco; Marta Toscano; Juan M Ilarregui; Gabriel A Rabinovich
Impact of protein-glycan interactions in the regulation of autoimmunity and chronic inflammation.
Autoimmunity reviews 2006;5(5):349-56.
2006: Marta D Romero; Juan C Muiño; German Ariel Bianco; Mercedes Ferrero; Claudio P Juarez; José D Luna; Gabriel A Rabinovich
Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis.
Investigative ophthalmology & visual science 2006;47(4):1550-6.
2006: Gabriel A Rabinovich; Albana Cumashi; German Ariel Bianco; Domenico Ciavardelli; Ida Iurisci; Maurizia D'Egidio; Enza Piccolo; Nicola Tinari; Nikolay E Nifantiev; Stefano Iacobelli
Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis.
Glycobiology 2006;16(3):210-20.
2006: Nidia N Gomez; Roberto C Davicino; Veronica S Biaggio; German Ariel Bianco; Silvina M Alvarez; Patricia Fischer; Lucas D Masnatta; Gabriel A Rabinovich; María S Gimenez
Overexpression of inducible nitric oxide synthase and cyclooxygenase-2 in rat zinc-deficient lung: Involvement of a NF-kappaB dependent pathway.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;14(1):30-8.
2006: Marta Toscano; Juan M Ilarregui; German Ariel Bianco; Natalia Rubinstein; Gabriel A Rabinovich
[How do protein-glycan interactions regulate T-cell physiology?].
Medicina 2006;66(4):357-62.
2005: Juan M Ilarregui; German Ariel Bianco; Marta Toscano; Gabriel A Rabinovich
The coming of age of galectins as immunomodulatory agents: impact of these carbohydrate binding proteins in T cell physiology and chronic inflammatory disorders.
Annals of the rheumatic diseases 2005;64 Suppl 4():iv96-103.
2005: M I Gonzalez; Natalia Rubinstein; Juan M Ilarregui; Marta Toscano; Norberto A Sanjuan; Gabriel A Rabinovich
Regulated expression of galectin-1 after in vitro productive infection with herpes simplex virus type 1: implications for T cell apoptosis.
International journal of immunopathology and pharmacology 2005;18(4):615-23.
2005: Andrea P Martín; Luciana Vieira de Moraes; Carlos Eduardo Tadokoro; Alessandra G Commodaro; Enrique Urrets-Zavalia; Gabriel A Rabinovich; Julio Urrets-Zavalia; Luiz Vicente Rizzo; Horacio Marcelo Serra
Administration of a peptide inhibitor of alpha4-integrin inhibits the development of experimental autoimmune uveitis.
Investigative ophthalmology & visual science 2005;46(6):2056-63.
2005: Gabriela C Fernández; Juan M Ilarregui; Carolina Rubel; Marta Toscano; Sonia A Gómez; Macarena Beigier-Bompadre; Martín A Isturiz; Gabriel A Rabinovich; Marina S Palermo
Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: involvement of alternative MAPK pathways.
Glycobiology 2005;15(5):519-27.
2005: Gabriel A Rabinovich
Galectin-1 as a potential cancer target.
British journal of cancer 2005;92(7):1188-92.
2005: Gabriel A Rabinovich; Adriana Gruppi
Galectins as immunoregulators during infectious processes: from microbial invasion to the resolution of the disease.
Parasite immunology 2005;27(4):103-14.
2005: Paola Matarrese; Antonella Tinari; Elisabetta Mormone; German Ariel Bianco; Marta Toscano; Barbara Ascione; Gabriel A Rabinovich; Walter Malorni
Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission.
The Journal of biological chemistry 2005;280(8):6969-85.
2004: Mercedes B Fuertes; Luciana L Molinero; Marta Toscano; Juan M Ilarregui; Natalia Rubinstein; Leonardo Fainboim; Norberto Zwirner; Gabriel A Rabinovich
Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase.
Molecular and cellular biochemistry 2004;267(1-2):177-85.
2004: Luciana L Molinero; Mercedes B Fuertes; María Victoria Girart; Leonardo Fainboim; Gabriel A Rabinovich; Monica Costas; Norberto Zwirner
NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5583-90.
2004: Natalia Rubinstein; Juan M Ilarregui; Marta Toscano; Gabriel A Rabinovich
The role of galectins in the initiation, amplification and resolution of the inflammatory response.
Tissue antigens 2004;64(1):1-12.
2004: Natalia Rubinstein; Mariano Alvarez; Norberto Zwirner; Marta Toscano; Juan M Ilarregui; Alicia Bravo; José Mordoh; Leonardo Fainboim; Osvaldo L Podhajcer; Gabriel A Rabinovich
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege.
Cancer cell 2004;5(3):241-51.
2004: Rosanna Ramhorst; Verónica E García; Adriana Corigliano; Gabriel A Rabinovich; Leonardo Fainboim
Identification of RANTES as a novel immunomodulator of the maternal allogeneic response.
Clinical immunology (Orlando, Fla.) 2004;110(1):71-80.
2004: Gabriel A Rabinovich; Marta Toscano; Juan M Ilarregui; Natalia Rubinstein
Shedding light on the immunomodulatory properties of galectins: novel regulators of innate and adaptive immune responses.
Glycoconjugate journal 2004;19(7-9):565-73.
2004: Eva V Acosta Rodríguez; Carolina L Montes; Claudia C Motrán; Elina I Zuniga; Fu-Tong Liu; Gabriel A Rabinovich; Adriana Gruppi
Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):493-502.
2003: Luciana L Molinero; Mercedes B Fuertes; Leonardo Fainboim; Gabriel A Rabinovich; Norberto Zwirner
Up-regulated expression of MICA on activated T lymphocytes involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase, and calcineurin.
Journal of leukocyte biology 2003;73(6):815-22.
2003: Luca Santucci; Stefano Fiorucci; Natalia Rubinstein; Andrea Mencarelli; Barbara Palazzetti; Barbara Federici; Gabriel A Rabinovich; Antonio Morelli
Galectin-1 suppresses experimental colitis in mice.
Gastroenterology 2003;124(5):1381-94.
2003: Silvia G Correa; Claudia E Sotomayor; Maria P Aoki; Cristina A Maldonado; Gabriel A Rabinovich
Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophages.
Glycobiology 2003;13(2):119-28.
2003: Luis Dettin; Natalia Rubinstein; Agustín Aoki; Gabriel A Rabinovich; Cristina A Maldonado
Regulated expression and ultrastructural localization of galectin-1, a proapoptotic beta-galactoside-binding lectin, during spermatogenesis in rat testis.
Biology of reproduction 2003;68(1):51-9.
2002: Gabriel A Rabinovich; Natalia Rubinstein; Marta Toscano
Role of galectins in inflammatory and immunomodulatory processes.
Biochimica et biophysica acta 2002;1572(2-3):274-84.
2002: Gabriel A Rabinovich; Linda G Baum; Nicola Tinari; Roberto Paganelli; Clara Natoli; Fu-Tong Liu; Stefano Iacobelli
Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?
Trends in immunology 2002;23(6):313-20.
2002: Gabriel A Rabinovich; Rosanna Ramhorst; Natalia Rubinstein; Adriana Corigliano; M Cecilia Daroqui; E B Kier-Joffé; Leonardo Fainboim
Induction of allogenic T-cell hyporesponsiveness by galectin-1-mediated apoptotic and non-apoptotic mechanisms.
Cell death and differentiation 2002;9(6):661-70.
2002: Luciana L Molinero; Mercedes B Fuertes; Gabriel A Rabinovich; Leonardo Fainboim; Norberto Zwirner
Activation-induced expression of MICA on T lymphocytes involves engagement of CD3 and CD28.
Journal of leukocyte biology 2002;71(5):791-7.
2002: Gabriel A Rabinovich; Natalia Rubinstein; Leonardo Fainboim
Unlocking the secrets of galectins: a challenge at the frontier of glyco-immunology.
Journal of leukocyte biology 2002;71(5):741-52.
2002: Gabriel A Rabinovich; Natalia Rubinstein; Pablo Matar; Viviana R Rozados; Silvia I Gervasoni; Graciela O Scharovsky
The antimetastatic effect of a single low dose of cyclophosphamide involves modulation of galectin-1 and Bcl-2 expression.
Cancer immunology, immunotherapy : CII 2002;50(11):597-603.
2001: Elina Zúñiga; Adriana Gruppi; J Hirabayashi; K I Kasai; Gabriel A Rabinovich
Regulated expression and effect of galectin-1 on Trypanosoma cruzi-infected macrophages: modulation of microbicidal activity and survival.
Infection and immunity 2001;69(11):6804-12.
2001: M Harjacek; Salvador J. Diaz-Cano; M De Miguel; H Wolfe; Cristina A Maldonado; Gabriel A Rabinovich
Expression of galectins-1 and -3 correlates with defective mononuclear cell apoptosis in patients with juvenile idiopathic arthritis.
The Journal of rheumatology 2001;28(8):1914-22.
2001: Elina Zuñiga; Gabriel A Rabinovich; M Mercedes Iglesias; Adriana Gruppi
Regulated expression of galectin-1 during B-cell activation and implications for T-cell apoptosis.
Journal of leukocyte biology 2001;70(1):73-9.
2001: Laura Giordanengo; Susana Gea; Gustavo Barbieri; Gabriel A Rabinovich
Anti-galectin-1 autoantibodies in human Trypanosoma cruzi infection: differential expression of this beta-galactoside-binding protein in cardiac Chagas' disease.
Clinical and experimental immunology 2001;124(2):266-73.
2001: M C Salamone; Gabriel A Rabinovich; A K Mendiguren; Gabriela Salamone; Leonardo Fainboim
Activation-induced expression of CD1d antigen on mature T cells.
Journal of leukocyte biology 2001;69(2):207-14.
2001: Gabriel A Rabinovich; Natalia Rubinstein
[Galectins: a novel family of proteins involved in the regulation of the immune response. Implications in immunopathological processes].
Medicina 2001;61(1):85-92.
2000: Gabriel A Rabinovich; C R Alonso; Claudia E Sotomayor; S Durand; José Luis Bocco; Clelia M Riera
Molecular mechanisms implicated in galectin-1-induced apoptosis: activation of the AP-1 transcription factor and downregulation of Bcl-2.
Cell death and differentiation 2000;7(8):747-53.
2000: Gabriel A Rabinovich; Claudia E Sotomayor; Clelia M Riera; Ismael D Bianco; Silvia G Correa
Evidence of a role for galectin-1 in acute inflammation.
European journal of immunology 2000;30(5):1331-9.
2000: Gabriel A Rabinovich
Apoptosis as a target for gene therapy in rheumatoid arthritis.
Memórias do Instituto Oswaldo Cruz 2000;95 Suppl 1():225-33.
2000: Claudia E Sotomayor; Gabriel A Rabinovich
"Galectin-1 induces central and peripheral cell death: implications in T-cell physiopathology".
Developmental immunology 2000;7(2-4):117-29.
1999: Cristina A Maldonado; Leonardo F Castagna; Gabriel A Rabinovich; CA Landa
Immunocytochemical study of the distribution of a 16-kDa galectin in the chicken retina.
Investigative ophthalmology & visual science 1999;40(12):2971-7.
1999: Gabriel A Rabinovich; Gordon M Daly; Hanna Dreja; H Tailor; Clelia M Riera; J Hirabayashi; Yuti Chernajovsky
Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis.
The Journal of experimental medicine 1999;190(3):385-98.
1999: Gabriel A Rabinovich
Galectins: an evolutionarily conserved family of animal lectins with multifunctional properties; a trip from the gene to clinical therapy.
Cell death and differentiation 1999;6(8):711-21.
1999: Gabriel A Rabinovich; Amiram Ariel; Rami Hershkoviz; J Hirabayashi; K I Kasai; Ofer Lider
Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1.
Immunology 1999;97(1):100-6.
1999: Gabriel A Rabinovich; Clelia M Riera; Claudia E Sotomayor
Galectin-1, an alternative signal for T cell death, is increased in activated macrophages.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1999;32(5):557-67.
1999: Gabriel A Rabinovich; Clelia M Riera; CA Landa; Claudia E Sotomayor
Galectins: a key intersection between glycobiology and immunology.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1999;32(4):383-93.
1999: Gabriel A Rabinovich; Clelia M Riera; Pablo Iribarren
Granulocyte-macrophage colony-stimulating factor protects dendritic cells from liposome-encapsulated dichloromethylene diphosphonate-induced apoptosis through a Bcl-2-mediated pathway.
European journal of immunology 1999;29(2):563-70.
1998: María C Sánchez; Gustavo A Chiabrando; Hugo A Guglielmone; Gustavo R Bonacci; Gabriel A Rabinovich; Miguel Angel Vides
Interaction of human tissue plasminogen activator (t-PA) with pregnancy zone protein: a comparative study with t-PA-alpha2-macroglobulin interaction.
Journal of biochemistry 1998;124(2):274-9.
1998: Gabriel A Rabinovich; M Mercedes Iglesias; NM Modesti; Leonardo F Castagna; Carlota Wolfenstein-Todel; Clelia M Riera; Claudia E Sotomayor
Activated rat macrophages produce a galectin-1-like protein that induces apoptosis of T cells: biochemical and functional characterization.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(10):4831-40.
1998: M Mercedes Iglesias; Gabriel A Rabinovich; V Ivanovic; Claudia E Sotomayor; Carlota Wolfenstein-Todel
Galectin-1 from ovine placenta--amino-acid sequence, physicochemical properties and implications in T-cell death.
European journal of biochemistry / FEBS 1998;252(3):400-7.
1998: M Mercedes Iglesias; Gabriel A Rabinovich; Andrea L Ambrosio; Leonardo F Castagna; Claudia E Sotomayor; Carlota Wolfenstein-Todel
Purification of galectin-3 from ovine placenta: developmentally regulated expression and immunological relevance.
Glycobiology 1998;8(1):59-65.
1997: Gabriel A Rabinovich; NM Modesti; Leonardo F Castagna; CA Landa; Clelia M Riera; Claudia E Sotomayor
Specific inhibition of lymphocyte proliferation and induction of apoptosis by CLL-I, a beta-galactoside-binding lectin.
Journal of biochemistry 1997;122(2):365-73.
1996: Gabriel A Rabinovich; Leonardo F Castagna; CA Landa; Clelia M Riera; Carlos P Sotomayor
Regulated expression of a 16-kd galectin-like protein in activated rat macrophages.
Journal of leukocyte biology 1996;59(3):363-70.