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Hannah Rabinowich

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TOP 3
Wen Hou; Jie Han; Caisheng Lu; Leslie A Goldstein; Hannah Rabinowich
Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis.
Jie Han; Leslie A Goldstein; Wen Hou; BRIAN GASTMAN; Hannah Rabinowich
Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.
Jie Han; Leslie A Goldstein; Wen Hou; Christopher J Froelich; simon simon watkins; Hannah Rabinowich
Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.

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All Publications

2010: Wen Hou; Jie Han; Caisheng Lu; Leslie A Goldstein; Hannah Rabinowich
Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis.
Autophagy 2010;6(7):891-900.
2010: Jie Han; Leslie A Goldstein; Wen Hou; BRIAN GASTMAN; Hannah Rabinowich
Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.
The Journal of biological chemistry 2010;285(29):22473-83.
2010: Jie Han; Leslie A Goldstein; Wen Hou; Christopher J Froelich; simon simon watkins; Hannah Rabinowich
Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.
The Journal of biological chemistry 2010;285(29):22461-72.
2010: Malgorzata Czystowska; Laura Strauss; Christoph Bergmann; Marta Szajnik; Hannah Rabinowich; Theresa L Whiteside
Reciprocal granzyme/perforin-mediated death of human regulatory and responder T cells is regulated by interleukin-2 (IL-2).
Journal of molecular medicine (Berlin, Germany) 2010;88(6):577-88.
2008: Wen Hou; Jie Han; Caisheng Lu; Leslie A Goldstein; Hannah Rabinowich
Enhancement of tumor-TRAIL susceptibility by modulation of autophagy.
Autophagy 2008;4(7):940-3.
2008: Ying-Hong Shi; Wen-Xing Ding; Jian Zhou; Jun-Yi He; Yang Xu; Andrea A Gambotto; Hannah Rabinowich; Jia Fan; Xiao-Ming Yin
Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence.
Hepatology (Baltimore, Md.) 2008;48(2):497-507.
2008: Jie Han; Wen Hou; Leslie A Goldstein; Caisheng Lu; Donna B Stolz; Xiao-Ming Yin; Hannah Rabinowich
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells.
The Journal of biological chemistry 2008;283(28):19665-77.
2007: Jie Han; Leslie A Goldstein; Wen Hou; Hannah Rabinowich
Functional linkage between NOXA and Bim in mitochondrial apoptotic events.
The Journal of biological chemistry 2007;282(22):16223-31.
2007: Norimasa Ito; Richard A DeMarco; Robbie B Mailliard; Jie Han; Hannah Rabinowich; Pawel Kalinski; Donna B Stolz; Herbert J Zeh; Michael T Lotze
Cytolytic cells induce HMGB1 release from melanoma cell lines.
Journal of leukocyte biology 2007;81(1):75-83.
2006: Jie Han; Leslie A Goldstein; BRIAN GASTMAN; Hannah Rabinowich
Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis.
The Journal of biological chemistry 2006;281(15):10153-63.
2005: Jie Han; Leslie A Goldstein; BRIAN GASTMAN; Asaf Rabinovitz; Hannah Rabinowich
Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
The Journal of biological chemistry 2005;280(16):16383-92.
2004: Jie Han; Leslie A Goldstein; BRIAN GASTMAN; Asaf Rabinovitz; Gui-qiang Wang; Bingliang Fang; Hannah Rabinowich
Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells.
Leukemia 2004;18(10):1671-80.
2004: Tae-Hyoung Kim; Yongge Zhao; Wen-Xing Ding; Jin Na Shin; Xi He; Young-Woo Seo; Jun Chen; Hannah Rabinowich; Andrew A Amoscato; Xiao-Ming Yin
Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome C release.
Molecular biology of the cell 2004;15(7):3061-72.
2004: Jie Han; Leslie A Goldstein; BRIAN GASTMAN; Christopher J Froelich; Xiao-Ming Yin; Hannah Rabinowich
Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events.
The Journal of biological chemistry 2004;279(21):22020-9.
2004: BRIAN GASTMAN; Kent Wang; Jie Han; Zhen-yu Zhu; Xiaojun Huang; Gui-qiang Wang; Hannah Rabinowich; Elieser Gorelik
A novel apoptotic pathway as defined by lectin cellular initiation.
Biochemical and biophysical research communications 2004;316(1):263-71.
2003: Zhibao Mi; Xiaoli Lu; Jeffrey C Mai; Bobby G Ng; Guiqiang Wang; Eric R Lechman; simon simon watkins; Hannah Rabinowich; Paul D Robbins
Identification of a synovial fibroblast-specific protein transduction domain for delivery of apoptotic agents to hyperplastic synovium.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(2):295-305.
2002: Iris Kuss; Hannah Rabinowich; William Gooding; Robert Edwards; Theresa L Whiteside
Expression of zeta in T cells prior to interleukin-2 therapy as a predictor of response and survival in patients with ovarian carcinoma.
Cancer biotherapy & radiopharmaceuticals 2002;17(6):631-40.
2002: Eva Wieckowski; Gui-qiang Wang; BRIAN GASTMAN; Leslie A Goldstein; Hannah Rabinowich
Granzyme B-mediated degradation of T-cell receptor zeta chain.
Cancer research 2002;62(17):4884-9.
2002: Shuchen Li; Yongge Zhao; Xi He; Tae-Hyoung Kim; Diane K Kuharsky; Hannah Rabinowich; Jun Chen; Chunying Du; Xiao-Ming Yin
Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis.
The Journal of biological chemistry 2002;277(30):26912-20.
2001: Gui-qiang Wang; Eva Wieckowski; Leslie A Goldstein; BRIAN GASTMAN; Asaf Rabinovitz; Andrea Gambotto; Shuchen Li; Bingliang Fang; Xiao-Ming Yin; Hannah Rabinowich
Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells.
The Journal of experimental medicine 2001;194(9):1325-37.
2001: C M Matsko; Oriana C Hunter; Hannah Rabinowich; Michael T Lotze; Andrew A Amoscato
Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis.
Biochemical and biophysical research communications 2001;287(5):1112-20.
2001: Gui-qiang Wang; BRIAN GASTMAN; Eva Wieckowski; Leslie A Goldstein; Andrea Gambotto; Tae-Hyoung Kim; Bingliang Fang; Asaf Rabinovitz; Xiao-Ming Yin; Hannah Rabinowich
A role for mitochondrial Bak in apoptotic response to anticancer drugs.
The Journal of biological chemistry 2001;276(36):34307-17.
2001: Clemens Esche; Galina V Shurin; John M Kirkwood; G Q Wang; Hannah Rabinowich; Georgi Pirtskhalaishvili; Michael R Shurin
Tumor necrosis factor-alpha-promoted expression of Bcl-2 and inhibition of mitochondrial cytochrome c release mediate resistance of mature dendritic cells to melanoma-induced apoptosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):974s-979s.
2001: Gui-qiang Wang; BRIAN GASTMAN; Eva Wieckowski; Leslie A Goldstein; Asaf Rabinovitz; Xiao-Ming Yin; Hannah Rabinowich
Apoptosis-resistant mitochondria in T cells selected for resistance to Fas signaling.
The Journal of biological chemistry 2001;276(5):3610-9.
2000: BRIAN GASTMAN; Xiao-Ming Yin; Daniel E Johnson; Eva Wieckowski; Gui-qiang Wang; simon simon watkins; Hannah Rabinowich
Tumor-induced apoptosis of T cells: amplification by a mitochondrial cascade.
Cancer research 2000;60(24):6811-7.
2000: Daniel E Johnson; BRIAN GASTMAN; Eva Wieckowski; Gui-qiang Wang; Andrew A Amoscato; Scott M Delach; Hannah Rabinowich
Inhibitor of apoptosis protein hILP undergoes caspase-mediated cleavage during T lymphocyte apoptosis.
Cancer research 2000;60(7):1818-23.
2000: BRIAN GASTMAN; Daniel E Johnson; Theresa L Whiteside; Hannah Rabinowich
Tumor-induced apoptosis of T lymphocytes: elucidation of intracellular apoptotic events.
Blood 2000;95(6):2015-23.
1999: BRIAN GASTMAN; Y Atarshi; Torsten E Reichert; T Saito; Levent Balkir; Hannah Rabinowich; Theresa L Whiteside
Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes.
Cancer research 1999;59(20):5356-64.
1999: Diana Metes; M Manciulea; D Pretrusca; Hannah Rabinowich; Linda K Ernst; iulia popescu; Ana Calugaru; A Sulica; William Chambers; Ronald Herberman; Penelope A Morel
Ligand binding specificities and signal transduction pathways of Fc gamma receptor IIc isoforms: the CD32 isoforms expressed by human NK cells.
European journal of immunology 1999;29(9):2842-52.
1999: Clemens Esche; Anna Lokshin; Galina V Shurin; BRIAN GASTMAN; Hannah Rabinowich; simon simon watkins; Michael T Lotze; Michael R Shurin
Tumor's other immune targets: dendritic cells.
Journal of leukocyte biology 1999;66(2):336-44.
1999: BRIAN GASTMAN; Daniel E Johnson; Theresa L Whiteside; Hannah Rabinowich
Caspase-mediated degradation of T-cell receptor zeta-chain.
Cancer research 1999;59(7):1422-7.
1998: Torsten E Reichert; Hannah Rabinowich; J T Johnson; Theresa L Whiteside
Mechanisms responsible for signaling and functional defects.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1998;21(4):295-306.
1998: Theresa L Whiteside; Hannah Rabinowich
The role of Fas/FasL in immunosuppression induced by human tumors.
Cancer immunology, immunotherapy : CII 1998;46(4):175-84.
1998: Hannah Rabinowich; Torsten E Reichert; Y Kashii; BRIAN GASTMAN; Maria C Bell; Theresa L Whiteside
Lymphocyte apoptosis induced by Fas ligand- expressing ovarian carcinoma cells. Implications for altered expression of T cell receptor in tumor-associated lymphocytes.
The Journal of clinical investigation 1998;101(11):2579-88.
1998: Yoshinori Suminami; Y Kashii; John C Law; W C Lin; Joanna Stanson; Torsten E Reichert; Hannah Rabinowich; Theresa L Whiteside
Molecular analysis of the IL-2 receptor beta chain gene expressed in human tumor cells.
Oncogene 1998;16(10):1309-17.
1997: P Lai; Hannah Rabinowich; Peggy A Crowley-Nowick; Maria C Bell; G Mantovani; Theresa L Whiteside
Alterations in expression and function of signal transducing proteins in tumor-associated T and natural killer cells in ovarian carcinoma.
Biochemical Society transactions 1997;25(2):218S.
1996: Hannah Rabinowich; Yoshinori Suminami; Torsten E Reichert; Peggy A Crowley-Nowick; M Bell; R Edwards; Theresa L Whiteside
Expression of cytokine genes or proteins and signaling molecules in lymphocytes associated with human ovarian carcinoma.
International journal of cancer. Journal international du cancer 1996;68(3):276-84.
1996: Hannah Rabinowich; M Manciulea; Ronald Herberman; Theresa L Whiteside
Beta1 integrin-mediated activation of focal adhesion kinase and its association with Fyn and Zap-70 in human NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):3860-8.
1996: Hannah Rabinowich; M Manciulea; Diana Metes; A Sulica; Ronald Herberman; Seth J Corey; Theresa L Whiteside
Physical and functional association of Fc mu receptor on human natural killer cells with the zeta- and Fc epsilon RI gamma-chains and with src family protein tyrosine kinases.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1485-91.
1996: Hannah Rabinowich; M Banks; Torsten E Reichert; Theodore F Logan; John M Kirkwood; Theresa L Whiteside
Expression and activity of signaling molecules in T lymphocytes obtained from patients with metastatic melanoma before and after interleukin 2 therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(8):1263-74.
1996: Markus J Maeurer; D Martin; Wolfgang Walter; K Liu; L Zitvogel; K Halusczcak; Hannah Rabinowich; R Duquesnoy; Walter J Storkus; Michael T Lotze
Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin.
The Journal of experimental medicine 1996;183(4):1681-96.
1996: M Manciulea; Hannah Rabinowich; A Sulica; W C Lin; Theresa L Whiteside; Albert B DeLeo; Ronald Herberman; Seth J Corey
Divergent phosphotyrosine signaling via Fc gamma RIIIA on human NK cells.
Cellular immunology 1996;167(1):63-71.
1996: P Lai; Hannah Rabinowich; Peggy A Crowley-Nowick; Maria C Bell; Giovanni Mantovani; Theresa L Whiteside
Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(1):161-73.
1995: Hannah Rabinowich; W C Lin; M Manciulea; Ronald Herberman; Theresa L Whiteside
Induction of protein tyrosine phosphorylation in human natural killer cells by triggering via alpha 4 beta 1 or alpha 5 beta 1 integrins.
Blood 1995;85(7):1858-64.
1995: Hannah Rabinowich; W C Lin; Andrew A Amoscato; Ronald Herberman; Theresa L Whiteside
Expression of vitronectin receptor on human NK cells and its role in protein phosphorylation, cytokine production, and cell proliferation.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(3):1124-35.
1995: A Sulica; William Chambers; M Manciulea; Diana Metes; Seth J Corey; Hannah Rabinowich; Theresa L Whiteside; Ronald Herberman
Divergent signal transduction pathways and effects on natural killer cell functions induced by interaction of Fc receptors with physiologic ligands or antireceptor antibodies.
Natural immunity 1995;14(3):123-33.
1994: Diana Metes; C Galatiuc; I Moldovan; Penelope A Morel; William Chambers; Albert B DeLeo; Hannah Rabinowich; R Schall; Theresa L Whiteside; A Sulica
Expression and function of Fc gamma RII on human natural killer cells.
Natural immunity 1994;13(6):289-300.
1994: Hannah Rabinowich; W C Lin; Ronald Herberman; Theresa L Whiteside
Signaling via CD7 molecules on human NK cells. Induction of tyrosine phosphorylation and beta 1 integrin-mediated adhesion to fibronectin.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(8):3504-13.
1994: Hannah Rabinowich; L Pricop; Ronald Herberman; Theresa L Whiteside
Expression and function of CD7 molecule on human natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):517-26.
1993: Hannah Rabinowich; Ronald Herberman; Theresa L Whiteside
Differential effects of IL12 and IL2 on expression and function of cellular adhesion molecules on purified human natural killer cells.
Cellular immunology 1993;152(2):481-98.
1993: Nikola L Vujanovic; Hannah Rabinowich; Y J Lee; L Jost; Ronald Herberman; Theresa L Whiteside
Distinct phenotypic and functional characteristics of human natural killer cells obtained by rapid interleukin 2-induced adherence to plastic.
Cellular immunology 1993;151(1):133-57.
1993: L Pricop; Hannah Rabinowich; P A Morel; A Sulica; Theresa L Whiteside; Ronald Herberman
Characterization of the Fc mu receptor on human natural killer cells. Interaction with its physiologic ligand, human normal IgM, specificity of binding, and functional effects.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(6):3018-29.
1993: D Vitolo; Nikola L Vujanovic; Hannah Rabinowich; M Schlesinger; Ronald Herberman; Theresa L Whiteside
Rapid Il-2-induced adherence of human natural killer cells. Expression of mRNA for cytokines and IL-2 receptors in adherent NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):1926-37.
1993: Hannah Rabinowich; P Sedlmayr; Ronald Herberman; Theresa L Whiteside
Response of human NK cells to IL-6 alterations of the cell surface phenotype, adhesion to fibronectin and laminin, and tumor necrosis factor-alpha/beta secretion.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(11):4844-55.
1992: Hannah Rabinowich; D Vitolo; S Altarac; Ronald Herberman; Theresa L Whiteside
Role of cytokines in the adoptive immunotherapy of an experimental model of human head and neck cancer by human IL-2-activated natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(1):340-9.
1992: P Sedlmayr; Hannah Rabinowich; A Winkelstein; Ronald Herberman; Theresa L Whiteside
Generation of adherent lymphokine activated killer (A-LAK) cells from patients with acute myelogenous leukaemia.
British journal of cancer 1992;65(2):222-8.
1991: P Sedlmayr; Hannah Rabinowich; E M Elder; M S Ernstoff; J M Kirkwood; Ronald Herberman; Theresa L Whiteside
Depressed ability of patients with melanoma or renal cell carcinoma to generate adherent lymphokine-activated killer cells.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1991;10(5):336-46.
1991: Hannah Rabinowich; P Sedlmayr; Ronald Herberman; Theresa L Whiteside
Increased proliferation, lytic activity, and purity of human natural killer cells cocultured with mitogen-activated feeder cells.
Cellular immunology 1991;135(2):454-70.
1991: M Sacchi; D Vitolo; P Sedlmayr; Hannah Rabinowich; Jonas T Johnson; Ronald Herberman; Theresa L Whiteside
Induction of tumor regression in experimental model of human head and neck cancer by human A-LAK cells and IL-2.
International journal of cancer. Journal international du cancer 1991;47(5):784-91.
1991: Adriana Zeevi; Hannah Rabinowich; Samuel A Yousem; I L Paradis; James H Dauber; Robert L Kormos; J Armitage; R Hardesty; Bartley P Griffith; Rene J Duquesnoy
Presence of donor-specific alloreactivity in histologically normal lung allografts is predictive of subsequent bronchiolitis obliterans.
Transplantation proceedings 1991;23(1 Pt 2):1128-9.
1991: Robert J Keenan; M E Lega; J S Dummer; I L Paradis; James H Dauber; Hannah Rabinowich; Samuel A Yousem; R L Hardesty; Bartley P Griffith; Rene J Duquesnoy
Cytomegalovirus serologic status and postoperative infection correlated with risk of developing chronic rejection after pulmonary transplantation.
Transplantation 1991;51(2):433-8.
1990: R H Dal Col; Adriana Zeevi; Hannah Rabinowich; D B Herlan; Samuel A Yousem; Bartley P Griffith
Donor-specific cytotoxicity testing: an advance in detecting pulmonary allograft rejection.
The Annals of thoracic surgery 1990;49(5):754-8.
1990: Samuel A Yousem; J M Curley; James H Dauber; I Paradis; Hannah Rabinowich; Adriana Zeevi; Rene J Duquesnoy; R Dowling; Marco A Zenati; R Hardesty
HLA-class II antigen expression in human heart-lung allografts.
Transplantation 1990;49(5):991-5.
1990: Samuel A Yousem; I L Paradis; J A Dauber; Adriana Zeevi; Hannah Rabinowich; Rene J Duquesnoy; R Hardesty; Bartley P Griffith
Large airway inflammation in heart-lung transplant recipients--its significance and prognostic implications.
Transplantation 1990;49(3):654-6.
1990: Hannah Rabinowich; Adriana Zeevi; I L Paradis; Samuel A Yousem; James H Dauber; Robert L Kormos; R L Hardesty; Bartley P Griffith; Rene J Duquesnoy
Proliferative responses of bronchoalveolar lavage lymphocytes from heart-lung transplant patients.
Transplantation 1990;49(1):115-21.
1990: I Paradis; Hannah Rabinowich; A Zeevi; S Yousem; Blakeslee Noyes; R Hoffman; Bartley P Griffith; James H Dauber
Life in the allogeneic environment after lung transplantation.
Lung 1990;168 Suppl():1172-81.
1988: Bartley P Griffith; I L Paradis; Adriana Zeevi; Hannah Rabinowich; Samuel A Yousem; Rene J Duquesnoy; James H Dauber; R L Hardesty
Immunologically mediated disease of the airways after pulmonary transplantation.
Annals of surgery 1988;208(3):371-8.
1988: Adriana Zeevi; Hannah Rabinowich; I Paradis; S Gryzan; James H Dauber; R L Hardesty; B Kormos; Bartley P Griffith; Rene J Duquesnoy
Lymphocyte activation in bronchoalveolar lavages from heart-lung transplant recipients.
Transplantation proceedings 1988;20(2):189-92.
1987: Adriana Zeevi; Rene J Duquesnoy; G Eiras; Hannah Rabinowich; Satoru Todo; L Makowka; Thomas E Starzl
Immunosuppressive effect of FK-506 on in vitro lymphocyte alloactivation: synergism with cyclosporine A.
Transplantation proceedings 1987;19(5 Suppl 6):40-4.