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Maria Bewley

Research Profile

Procedures

X Ray Crystallography

Concepts & Ideas

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Phenomena

Protein Binding

Physiology

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Publications

TOP 3
Brian R Tash; Fang Tian; David Antonetti; Maria C Bewley; Kathleen A Griffin; Jason M Keil; Mariano Russo; Jeffrey M Sundstrom; John M Flanagan
The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability.
Matthew P Woll; Maria C Bewley; Dan A De Cotiis; Robert Levenson; Diana M Tacelosky; John M Flanagan
Interaction between the D2 dopamine receptor and neuronal calcium sensor-1 analyzed by fluorescence anisotropy.
Nicole Gudleski; John M Flanagan; Eileen P Ryan; Maria C Bewley; Leslie J Parent
Directionality of nucleocytoplasmic transport of the retroviral gag protein depends on sequential binding of karyopherins and viral RNA.

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All Publications

2012: Brian R Tash; Fang Tian; David Antonetti; Maria C Bewley; Kathleen A Griffin; Jason M Keil; Mariano Russo; Jeffrey M Sundstrom; John M Flanagan
The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(27):10855-60.
2011: Matthew P Woll; Maria C Bewley; Dan A De Cotiis; Robert Levenson; Diana M Tacelosky; John M Flanagan
Interaction between the D2 dopamine receptor and neuronal calcium sensor-1 analyzed by fluorescence anisotropy.
Biochemistry 2011;50(41):8780-91.
2010: Nicole Gudleski; John M Flanagan; Eileen P Ryan; Maria C Bewley; Leslie J Parent
Directionality of nucleocytoplasmic transport of the retroviral gag protein depends on sequential binding of karyopherins and viral RNA.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(20):9358-63.
2009: Maria C Bewley; Vito Graziano; Kathleen Griffin; John M Flanagan
Turned on for degradation: ATPase-independent degradation by ClpP.
Journal of structural biology 2009;165(2):118-25.
2007: Kun-Ming Chen; Thomas E Spratt; Bruce Stanley; Dan A De Cotiis; Maria C Bewley; John M Flanagan; Dhimant Desai; Arunangshu Das; Emerich Fiala; Shantu Amin; Karam El-Bayoumy
Inhibition of nuclear factor-kappaB DNA binding by organoselenocyanates through covalent modification of the p50 subunit.
Cancer research 2007;67(21):10475-83.
2006: Maria C Bewley; Vito Graziano; Jiangsheng Jiang; Eileen Matz; F William Studier; Anthony E Pegg; Catherine S Coleman; John M Flanagan
Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2063-8.
2006: Maria C Bewley; Vito Graziano; Kathleen Griffin; John M Flanagan
The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.
Journal of structural biology 2006;153(2):113-28.
2003: Maria C Bewley; C Ainsley Davis; Christopher C Marohnic; David Taormina; Michael J Barber
The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site.
Biochemistry 2003;42(45):13145-51.
2003: Christopher C Marohnic; Maria C Bewley; Michael J Barber
Engineering and characterization of a NADPH-utilizing cytochrome b5 reductase.
Biochemistry 2003;42(38):11170-82.
2003: Jason Howitt; Maria C Bewley; Vito Graziano; John M Flanagan; Paul Freimuth
Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor.
The Journal of biological chemistry 2003;278(28):26208-15.
2002: John M Flanagan; Maria C Bewley
Protein quality control in bacterial cells: integrated networks of chaperones and ATP-dependent proteases.
Genetic engineering 2002;24():17-47.
2001: Maria C Bewley; Christopher C Marohnic; Michael J Barber
The structure and biochemistry of NADH-dependent cytochrome b5 reductase are now consistent.
Biochemistry 2001;40(45):13574-82.
2000: Ross T A MacGillivray; Maria C Bewley; Clyde Smith; Qing-Yu He; Anne Mason; Robert C Woodworth; Edward N Baker
Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release.
Biochemistry 2000;39(6):1211-6.
1999: Maria C Bewley; Karen Springer; Yian-Biao Zhang; Paul Freimuth; John M Flanagan
Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR.
Science (New York, N.Y.) 1999;286(5444):1579-83.
1999: Maria C Bewley; Philip Jeffrey; ML Patchett; Z F Kanyo; Edward N Baker
Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure (London, England : 1993) 1999;7(4):435-48.
1999: Maria C Bewley; BM Tam; J Grewal; S He; Steven C Shewry; Michael E P Murphy; Anne Mason; Robert C Woodworth; Edward N Baker; Ross T A MacGillivray
X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32.
Biochemistry 1999;38(8):2535-41.
1999: Paul Freimuth; Karen Springer; C Berard; James F Hainfeld; Maria C Bewley; J Flanagan
Coxsackievirus and adenovirus receptor amino-terminal immunoglobulin V-related domain binds adenovirus type 2 and fiber knob from adenovirus type 12.
Journal of virology 1999;73(2):1392-8.
1998: Philip Jeffrey; Maria C Bewley; Ross T A MacGillivray; Anne Mason; Robert C Woodworth; Edward N Baker
Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.
Biochemistry 1998;37(40):13978-86.
1998: Ross T A MacGillivray; S A Moore; J Chen; Bryan F Anderson; H Baker; Y Luo; Maria C Bewley; Clyde Smith; Michael E P Murphy; Yili Wang; Anne Mason; Robert C Woodworth; Gary D Brayer; Edward N Baker
Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry 1998;37(22):7919-28.
1997: Teresa K Attwood; H Avison; ME Beck; Maria C Bewley; A J Bleasby; F Brewster; P Cooper; Kirill Degtyarenko; A J Geddes; Darren R Flower; M P Kelly; S Lott; K M Measures; DJ Parry-Smith; D N Perkins; P Scordis; D Scott; C Worledge
The PRINTS database of protein fingerprints: a novel information resource for computational molecular biology.
Journal of chemical information and computer sciences 1997;37(3):417-24.
1996: Maria C Bewley; J S Lott; Edward N Baker; M L Patchett
The cloning, expression and crystallisation of a thermostable arginase.
FEBS letters 1996;386(2-3):215-8.
1993: Maria C Bewley; C M Boustead; John H Walker; D A Waller; Robert Huber
Structure of chicken annexin V at 2.25-A resolution.
Biochemistry 1993;32(15):3923-9.
1992: John H Walker; C M Boustead; J J Koster; Maria C Bewley; D A Waller
Annexin V, a calcium-dependent phospholipid-binding protein.
Biochemical Society transactions 1992;20(4):828-33.