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Giles Rae

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Juliano M Martins; Giles A Rae; Denis M Soares; Miriam C C de Melo; Maria José Figueiredo; Daniela T Longhi-Balbinot; David do C Malvar; Glória E P Souza
Involvement of PGE2 and RANTES in Staphylococcus aureus-induced fever in rats.
Pedro D'Orléans-Juste; Ghassan Bkaily; Giles A Rae
Endothelin and bradykinin: 'brothers-in-arms' in Chagas vasculopathies?
David do C Malvar; Denis M Soares; Aline S C Fabrício; Alexandre Kanashiro; Renes R Machado; Maria J Figueiredo; Giles A Rae; Glória E P de Souza
The antipyretic effect of dipyrone is unrelated to inhibition of PGE(2) synthesis in the hypothalamus.

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2012: Juliano M Martins; Giles A Rae; Denis M Soares; Miriam C C de Melo; Maria José Figueiredo; Daniela T Longhi-Balbinot; David do C Malvar; Glória E P Souza
Involvement of PGE2 and RANTES in Staphylococcus aureus-induced fever in rats.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;113(9):1456-65.
2012: Pedro D'Orléans-Juste; Ghassan Bkaily; Giles A Rae
Endothelin and bradykinin: 'brothers-in-arms' in Chagas vasculopathies?
British journal of pharmacology 2012;165(5):1330-2.
2011: David do C Malvar; Denis M Soares; Aline S C Fabrício; Alexandre Kanashiro; Renes R Machado; Maria J Figueiredo; Giles A Rae; Glória E P de Souza
The antipyretic effect of dipyrone is unrelated to inhibition of PGE(2) synthesis in the hypothalamus.
British journal of pharmacology 2011;162(6):1401-9.
2010: Maria Fernanda P Werner; Marcello Trevisani; Barbara Campi; Eunice André; Pierangelo Geppetti; Giles A Rae
Contribution of peripheral endothelin ETA and ETB receptors in neuropathic pain induced by spinal nerve ligation in rats.
European journal of pain (London, England) 2010;14(9):911-7.
2010: Juliana Geremias Chichorro; Cibelle Ramos Fiuza; Elisangela Bressan; Rafaela Franco Claudino; Daniela Ferraz Leite; Giles A Rae
Endothelins as pronociceptive mediators of the rat trigeminal system: role of ETA and ETB receptors.
Brain research 2010;1345():73-83.
2010: Ana Paula Luiz; Samilla Driessen Schroeder; Juliana Geremias Chichorro; João Batista Calixto; Aleksander Roberto Zampronio; Giles A Rae
Kinin B(1) and B(2) receptors contribute to orofacial heat hyperalgesia induced by infraorbital nerve constriction injury in mice and rats.
Neuropeptides 2010;44(2):87-92.
2009: D Fraga; C I S Zanoni; Giles A Rae; Carlos A Parada; G E P Souza
Endogenous cannabinoids induce fever through the activation of CB1 receptors.
British journal of pharmacology 2009;157(8):1494-501.
2009: Emerson M Motta; Juliana G Chichorro; Pedro D'Orléans-Juste; Giles A Rae
Roles of endothelin ETA and ETB receptors in nociception and chemical, thermal and mechanical hyperalgesia induced by endothelin-1 in the rat hindpaw.
Peptides 2009;30(5):918-25.
2009: Juliana G Chichorro; Aleksander R Zampronio; Daniela A Cabrini; Celia R C Franco; Giles A Rae
Mechanisms operated by endothelin ETA and ETB receptors in the trigeminal ganglion contribute to orofacial thermal hyperalgesia induced by infraorbital nerve constriction in rats.
Neuropeptides 2009;43(2):133-42.
2008: Pedro D'Orléans-Juste; M Houde; Giles A Rae; Ghassan Bkaily; Emilie Carrier; E Simard
Endothelin-1 (1-31): from chymase-dependent synthesis to cardiovascular pathologies.
Vascular pharmacology 2008;49(2-3):51-62.
2007: M F P Werner; Candida Kassuya; Juliano Ferreira; Aleksander Roberto Zampronio; João B Calixto; Giles A Rae
Peripheral kinin B(1) and B(2) receptor-operated mechanisms are implicated in neuropathic nociception induced by spinal nerve ligation in rats.
Neuropharmacology 2007;53(1):48-57.
2007: Jarbas Mota Siqueira; Rodrigo Rebelo Peters; Andressa Córneo Gazola; Patrícia Baier Krepsky; Mareni Rocha Farias; Giles A Rae; Artur J de Brum-Fernandes; Rosa Maria Ribeiro-do-Valle
Anti-inflammatory effects of a triterpenoid isolated from Wilbrandia ebracteata Cogn.
Life sciences 2007;80(15):1382-7.
2006: Juliana Geremias Chichorro; Aleksander Roberto Zampronio; Glória E P Souza; Giles A Rae
Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs.
Pain 2006;123(1-2):64-74.
2006: Patrícia Gonçalves Trentin; Marcília Baticy Fernandes; Pedro D'Orléans-Juste; Giles A Rae
Endothelin-1 causes pruritus in mice.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):1146-51.
2006: Emerson Marcelo Motta; João B Calixto; Giles A Rae
Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):1141-5.
2006: Juliana Geremias Chichorro; Aleksander Roberto Zampronio; Giles A Rae
Endothelin ET(B) receptor antagonist reduces mechanical allodynia in rats with trigeminal neuropathic pain.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):1136-40.
2006: Janice Koepp; Charles Julian Lindsey; Emerson Marcelo Motta; Giles A Rae
Role of the paratrigeminal nucleus in nocifensive responses of rats to chemical, thermal and mechanical stimuli applied to the hind paw.
Pain 2006;122(3):235-44.
2006: Aline S.C. Fabricio; Giles A Rae; Aleksander Roberto Zampronio; Pedro D'Orléans-Juste; Glória E P Souza
Central endothelin ET(B) receptors mediate IL-1-dependent fever induced by preformed pyrogenic factor and corticotropin-releasing factor in the rat.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(1):R164-71.
2005: Aline S.C. Fabricio; Giles A Rae; Pedro D'Orléans-Juste; Glória E P Souza
Endothelin-1 as a central mediator of LPS-induced fever in rats.
Brain research 2005;1066(1-2):92-100.
2005: Janice Koepp; Cristofer André Caous; Giles A Rae; Antonio Claudir Balan; Charles Julian Lindsey
Kinin and opioid receptors in the paratrigeminal nucleus modulate the somatosensory reflex to rat sciatic nerve stimulation.
Peptides 2005;26(8):1339-45.
2005: Marie-Hélène Fecteau; Jean-Claude Honoré; Mirco Plante; Julie Labonté; Giles A Rae; Pedro D'Orléans-Juste
Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo.
Hypertension 2005;46(1):87-92.
2004: Joice M da Cunha; Giles A Rae; Sérgio H Ferreira; Fernando de Queiroz Cunha
Endothelins induce ETB receptor-mediated mechanical hypernociception in rat hindpaw: roles of cAMP and protein kinase C.
European journal of pharmacology 2004;501(1-3):87-94.
2004: Josélia Borba Daher; Glória E P Souza; Pedro D'Orléans-Juste; Giles A Rae
Endothelin ETB receptors inhibit articular nociception and priming induced by carrageenan in the rat knee-joint.
European journal of pharmacology 2004;496(1-3):77-85.
2004: André Luiz Franco Sampaio; Giles A Rae; M G M O Henriques
Effects of endothelin ETA receptor antagonism on granulocyte and lymphocyte accumulation in LPS-induced inflammation.
Journal of leukocyte biology 2004;76(1):210-6.
2004: Elaine Gavioli; Christopher W Vaughan; Giuliano Marzola; Remo Guerrini; V A Mitchell; Silvia Zucchini; Thereza C M De Lima; Giles A Rae; Severo Salvadori; Domenico Regoli; Girolamo Calo'
Antidepressant-like effects of the nociceptin/orphanin FQ receptor antagonist UFP-101: new evidence from rats and mice.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(6):547-53.
2004: Anna P Piovezan; Pedro D'Orléans-Juste; Monica Frighetto; Glória E P Souza; M G M O Henriques; Giles A Rae
Endothelins contribute towards nociception induced by antigen in ovalbumin-sensitised mice.
British journal of pharmacology 2004;141(4):755-63.
2003: Elaine Gavioli; Giuliano Marzola; Remo Guerrini; R Bertorelli; Silvia Zucchini; Thereza C M De Lima; Giles A Rae; Severo Salvadori; Domenico Regoli; Girolamo Calo
Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test.
The European journal of neuroscience 2003;17(9):1987-90.
2002: Cláudio L Guimarães; Patricia G Trentin; Giles A Rae
Endothelin ET(B) receptor-mediated mechanisms involved in oleic acid-induced acute lung injury in mice.
Clinical science (London, England : 1979) 2002;103 Suppl 48():340S-344S.
2002: Jean-Claude Honoré; Mirco Plante; Ghassan Bkaily; Giles A Rae; Pedro D'Orléans-Juste
Pressor and pulmonary responses to ET-1(1-31) in guinea-pigs.
British journal of pharmacology 2002;136(6):819-28.
2002: Elaine Gavioli; Giles A Rae; Girolamo Calo'; Remo Guerrini; Thereza C M De Lima
Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test.
British journal of pharmacology 2002;136(5):764-72.
2002: Yun-Guo Yu; Cristofer André Caous; Antonio Claudir Balan; Giles A Rae; Charles Julian Lindsey
Cardiovascular responses to sciatic nerve stimulation are blocked by paratrigeminal nucleus lesion.
Autonomic neuroscience : basic & clinical 2002;98(1-2):70-4.
2002: Alcíbia M Cardozo; Pedro D'Orléans-Juste; Ghassan Bkaily; Giles A Rae
Simultaneous changes in intracellular calcium and tension induced by endothelin-1 and sarafotoxin S6c in guinea pig isolated gallbladder: influence of indomethacin.
Canadian journal of physiology and pharmacology 2002;80(5):458-63.
2002: A H M Cardozo; Daniela Almeida Cabrini; Maria M Campos; Giles A Rae; J P Huidobro-Toro; João B Calixto
Diabetes-induced changes in responsiveness of rat bladder and vas deferens to peptides in vitro: susceptibility to reversal by insulin.
Canadian journal of physiology and pharmacology 2002;80(4):334-40.
2002: Janice Koepp; Alcíbia M Cardozo; Pedro D'Orléans-Juste; Giles A Rae
Influence of indomethacin on effects of endothelin-1 on guinea pig isolated rings of common bile duct and sphincter of Oddi.
European journal of pharmacology 2002;435(1):103-11.
2002: G E P De Souza; R A Cardoso; M C C Melo; Aline S.C. Fabricio; V M S Silva; Maximillian Lora; Artur J de Brum-Fernandes; Giles A Rae; S H Ferreira; Aleksander Roberto Zampronio
A comparative study of the antipyretic effects of indomethacin and dipyrone in rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(1):24-32.
2001: Maria M Campos; Daniela Almeida Cabrini; A H Cardozo; Giles A Rae; J H Toro; João B Calixto
Changes in paw oedema triggered via bradykinin B(1) and B(2) receptors in streptozotocin-diabetic rats.
European journal of pharmacology 2001;416(1-2):169-77.
2000: C L Guimarães; S Da-Silva; R Couture; Giles A Rae
Mixed endothelin ET(A) and ET(B) antagonist bosentan inhibits oleic acid-induced lung plasma extravasation in mouse.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S371-3.
2000: H C Nora; Alcíbia M Cardozo; P Dorléans-Juste; Giles A Rae
Influences of indomethacin on contractions induced by endothelins in guinea pig isolated gallbladder.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S267-9.
2000: Alcíbia M Cardozo; Janice Koepp; P Dorléans-Juste; Giles A Rae
Receptors mediating endothelin-1-induced contractions of rabbit gallbladder.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S264-6.
2000: André Luiz Franco Sampaio; Giles A Rae; M G M O Henriques
Participation of endogenous endothelins in delayed eosinophil and neutrophil recruitment in mouse pleurisy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49(4):170-6.
2000: Jean-Philippe Gratton; Giles A Rae; Ghassan Bkaily; Pedro D'Orléans-Juste
ET(B) receptor blockade potentiates the pressor response to big endothelin-1 but not big endothelin-2 in the anesthetized rabbit.
Hypertension 2000;35(3):726-31.
2000: Anna P Piovezan; Pedro D'Orléans-Juste; Glória E P Souza; Giles A Rae
Endothelin-1-induced ET(A) receptor-mediated nociception, hyperalgesia and oedema in the mouse hind-paw: modulation by simultaneous ET(B) receptor activation.
British journal of pharmacology 2000;129(5):961-8.
2000: André Luiz Franco Sampaio; Giles A Rae; M M Henriques
Role of endothelins on lymphocyte accumulation in allergic pleurisy.
Journal of leukocyte biology 2000;67(2):189-95.
1999: N Miasiro; H Karaki; Y Matsuda; Antonio C M Paiva; Giles A Rae
Effects of endothelin ET(B) receptor agonists and antagonists on the biphasic response in the ileum.
European journal of pharmacology 1999;369(2):205-13.
1999: K Lewis; Alain Cadieux; Giles A Rae; Jean-Philippe Gratton; Pedro D'Orléans-Juste
Nitric oxide limits the eicosanoid-dependent bronchoconstriction and hypotension induced by endothelin-1 in the guinea-pig.
British journal of pharmacology 1999;126(1):93-102.
1998: Aline S.C. Fabricio; CA Silva; Giles A Rae; Pedro D'Orléans-Juste; Glória E P Souza
Essential role for endothelin ET(B) receptors in fever induced by LPS (E. coli) in rats.
British journal of pharmacology 1998;125(3):542-8.
1998: J D De-Melo; Carlos Rogério Tonussi; Pedro D'Orléans-Juste; Giles A Rae
Articular nociception induced by endothelin-1, carrageenan and LPS in naive and previously inflamed knee-joints in the rat: inhibition by endothelin receptor antagonists.
Pain 1998;77(3):261-9.
1998: Anna P Piovezan; Pedro D'Orléans-Juste; Carlos Rogério Tonussi; Giles A Rae
Effects of endothelin-1 on capsaicin-induced nociception in mice.
European journal of pharmacology 1998;351(1):15-22.
1998: J D De-Melo; Carlos Rogério Tonussi; Pedro D'Orléans-Juste; Giles A Rae
Effects of endothelin-1 on inflammatory incapacitation of the rat knee joint.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S518-20.
1998: L G Luciano; Pedro D'Orléans-Juste; João B Calixto; Giles A Rae
Endothelin-1 selectively potentiates the purinergic component of sympathetic neurotransmission in rat seminal vesicle.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S515-7.
1998: K Lewis; Alain Cadieux; Giles A Rae; Pedro D'Orléans-Juste
L-NAME potentiates endothelin-stimulated thromboxane release from guinea pig lung.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S109-11.
1997: Anna P Piovezan; Pedro D'Orléans-Juste; Carlos Rogério Tonussi; Giles A Rae
Endothelins potentiate formalin-induced nociception and paw edema in mice.
Canadian journal of physiology and pharmacology 1997;75(6):596-600.
1997: Alcíbia M Cardozo; Pedro D'Orléans-Juste; M Yano; P A Frank; Giles A Rae
Influence of endothelin ET(A) and ET(B) receptor antagonists on endothelin-induced contractions of the guinea pig isolated gall bladder.
Regulatory peptides 1997;69(1):15-23.
1996: R M Teixeira; Adair R S Santos; S J Ribeiro; João B Calixto; Giles A Rae; Thereza C M De Lima
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
European journal of pharmacology 1996;311(1):7-14.
1995: Jean-Philippe Gratton; M C Maurice; Giles A Rae; Pedro D'Orléans-Juste
Pharmacological properties of endothelins and big endothelins in ketamine/xylazine or urethane anesthetized rats.
American journal of hypertension 1995;8(11):1121-7.
1995: J Maas; Giles A Rae; J P Huidobro-Toro; João B Calixto
Characterization of kinin receptors modulating neurogenic contractions of the mouse isolated vas deferens.
British journal of pharmacology 1995;114(7):1471-7.
1995: J Mass; Pedro D'Orléans-Juste; M Yano; Giles A Rae
Evidence for atypical endothelin receptors and for presence of endothelin-converting enzyme activity in the mouse isolated vas deferens.
European journal of pharmacology 1995;276(1-2):113-21.
1995: Jean-Philippe Gratton; Giles A Rae; A Claing; S Télémaque; Pedro D'Orléans-Juste
Different pressor and bronchoconstrictor properties of human big-endothelin-1, 2 (1-38) and 3 in ketamine/xylazine-anaesthetized guinea-pigs.
British journal of pharmacology 1995;114(3):720-6.
1995: Giles A Rae; João B Calixto; Pedro D'Orléans-Juste
Effects and mechanisms of action of endothelins on non-vascular smooth muscle of the respiratory, gastrointestinal and urogenital tracts.
Regulatory peptides 1995;55(1):1-46.
1995: L G Luciano; Pedro D'Orléans-Juste; João B Calixto; Giles A Rae
Endothelin-1 contracts and increases motor responses to ATP in rat seminal vesicle.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S91-4.
1995: A Claing; W Neugebauer; M Yano; Giles A Rae; Pedro D'Orléans-Juste
[Phe22]-big endothelin-1[19-37]: a new and potent inhibitor of the endothelin-converting enzyme.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S72-4.
1993: Giles A Rae; João B Calixto; Pedro D'Orléans-Juste
Big-endothelin-1 contracts rat isolated uterus via a phosphoramidon-sensitive endothelin ETA receptor-mediated mechanism.
European journal of pharmacology 1993;240(2-3):113-9.
1993: Giles A Rae; João B Calixto; Pedro D'Orléans-Juste
Conversion of big endothelin-1 in rat uterus causes contraction mediated by ETA receptors.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S192-5.
1992: C L Guimarães; Giles A Rae
Dual effects of endothelins -1, -2 and -3 on guinea pig field-stimulated ileum: possible mediation by two receptors coupled to pertussis toxin-insensitive mechanisms.
The Journal of pharmacology and experimental therapeutics 1992;261(3):1253-9.
1992: C L Guimarães; João B Calixto; Giles A Rae
Potent constrictor actions of endothelin-1, endothelin-2, and endothelin-3 in rat isolated portal vein.
Hypertension 1992;19(2 Suppl):II79-86.
1991: Thereza C M De Lima; Giles A Rae
Effects of cold-restraint and swim stress on convulsions induced by pentylenetetrazol and electroshock: influence of naloxone pretreatment.
Pharmacology, biochemistry, and behavior 1991;40(2):297-300.
1991: João B Calixto; Rosendo A Yunes; Giles A Rae
Effect of crude extracts from Leonotis nepetaefolia (Labiatae) on rat and guinea-pig smooth muscle and rat cardiac muscle.
The Journal of pharmacy and pharmacology 1991;43(8):529-34.
1991: João B Calixto; Giles A Rae
Effects of endothelins, Bay K 8644 and other oxytocics in non-pregnant and late pregnant rat isolated uterus.
European journal of pharmacology 1991;192(1):109-16.
1991: D S Corrêa; A C Rabetti; Giles A Rae
ATP-sensitive potassium channels do not mediate vasorelaxation by acetylcholine or iloprost.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1991;24(7):729-34.
1990: João B Calixto; Obdulio G Miguel; Rosendo A Yunes; Giles A Rae
Action of 2-hydroxy-4,6-dimethoxyacetophenone isolated from Sebastiania schottiana.
Planta medica 1990;56(1):31-5.
1990: Giles A Rae; G H Pereira; Thereza C M De Lima
The influence of stress on convulsive parameters in the mouse.
Neuroscience and biobehavioral reviews 1990;14(4):491-4.
1990: A P Batista-Da-Silva; Giles A Rae; Antonio Carobrez
Microinjection of D-2-amino-7-phosphonoheptanoate into the dorsal periaqueductal gray matter reduces the pressor response to glutamate injected at the same site.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1990;23(8):705-8.
1990: Giles A Rae
Availability of calcium for noradrenergic contraction of the mouse isolated vas deferens is not altered during tolerance to and dependence on morphine.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1990;23(3-4):307-15.
1990: Giles A Rae; João B Calixto
Effects of endothelins on nerve-mediated contractions of the mouse vas deferens.
Life sciences 1990;47(17):PL83-9.
1989: Gina Struffaldi Morato; João B Calixto; L Cordeiro; Thereza C M De Lima; Edelton F Morato; M Nicolau; Giles A Rae; R N Takahashi; R M Valle; Rosendo A Yunes
Chemical and pharmacological studies on Talauma ovata St. Hil. (Magnoliaceae).
Journal of ethnopharmacology 1989;26(3):277-86.
1989: Giles A Rae; João B Calixto
Interactions of calcium antagonists and the calcium channel agonist Bay K 8644 on neurotransmission of the mouse isolated vas deferens.
British journal of pharmacology 1989;96(2):333-40.
1988: Thereza C M De Lima; Giles A Rae
Participation of serotonergic mechanisms in the anticonvulsant effect of stress in mice treated with pentylenetetrazol.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1988;21(2):333-5.
1987: R N Takahashi; Gina Struffaldi Morato; Giles A Rae
Effects of ketamine on nociception and gastrointestinal motility in mice are unaffected by naloxone.
General pharmacology 1987;18(2):201-3.
1986: João B Calixto; Rosendo A Yunes; Obdulio G Miguel; Giles A Rae
Effects of Sebastiana schottiana extracts on isolated smooth muscle contraction.
Planta medica 1986;(6):444-5.
1986: Giles A Rae; R L Souza; R N Takahashi
Methylnalorphinium fails to reverse naloxone-sensitive stress-induced analgesia in mice.
Pharmacology, biochemistry, and behavior 1986;24(4):829-32.
1986: João B Calixto; M Nicolau; Giles A Rae
Pharmacological actions of tannic acid. I. Effects on isolated smooth and cardiac muscles and on blood pressure.
Planta medica 1986;(1):32-5.
1984: J B Calixto; Rosendo A Yunes; A S Neto; R M Valle; Giles A Rae
Antispasmodic effects of an alkaloid extracted from Phyllanthus sellowianus: a comparative study with papaverine.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1984;17(3-4):313-21.