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Marie-Edith Rafestin-Oblin

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Junaid A Khan; Marc Lombès; Hugues Loosfelt; Geri Meduri; Mouad Alami; Larbi Amazit; Jean-Daniel Brion; Nathalie Chabbert-Buffet; Jérôme Fagart; Michel Fay; abdallah hamze; Abdellatif Tikad; Marie-Edith Rafestin-Oblin
A new strategy for selective targeting of progesterone receptor with passive antagonists.
Jessica Huyet; Grégory PINON; Marie-Edith Rafestin-Oblin; Michel Raymond Fay; Jérôme Fagart
Structural determinants of ligand binding to the mineralocorticoid receptor.
Edwige-Ludiwyne Hubert; Xavier Jeunemaitre; Chantal Metz; Marie-Edith Rafestin-Oblin; Raphaël Teissier; Brigitte Escoubet; Michel Fay; Fábio L Fernandes-Rosa; Maria-Christina Zennaro
Mineralocorticoid receptor mutations and a severe recessive pseudohypoaldosteronism type 1.

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2013: Junaid A Khan; Marc Lombès; Hugues Loosfelt; Geri Meduri; Mouad Alami; Larbi Amazit; Jean-Daniel Brion; Nathalie Chabbert-Buffet; Jérôme Fagart; Michel Fay; abdallah hamze; Abdellatif Tikad; Marie-Edith Rafestin-Oblin
A new strategy for selective targeting of progesterone receptor with passive antagonists.
Molecular endocrinology (Baltimore, Md.) 2013;27(6):909-24.
2012: Jessica Huyet; Grégory PINON; Marie-Edith Rafestin-Oblin; Michel Raymond Fay; Jérôme Fagart
Structural determinants of ligand binding to the mineralocorticoid receptor.
Molecular and cellular endocrinology 2012;350(2):187-95.
2011: Edwige-Ludiwyne Hubert; Xavier Jeunemaitre; Chantal Metz; Marie-Edith Rafestin-Oblin; Raphaël Teissier; Brigitte Escoubet; Michel Fay; Fábio L Fernandes-Rosa; Maria-Christina Zennaro
Mineralocorticoid receptor mutations and a severe recessive pseudohypoaldosteronism type 1.
Journal of the American Society of Nephrology : JASN 2011;22(11):1997-2003.
2011: Fábio L Fernandes-Rosa; Edwige-Ludiwyne Hubert; Jérôme Fagart; Nicolas Tchitchek; Debora Gomes; Elodie Jouanno; Arndt Benecke; Marie-Edith Rafestin-Oblin; Xavier Jeunemaitre; Sonir R Antonini; Maria-Christina Zennaro
Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1.
The Journal of clinical endocrinology and metabolism 2011;96(3):E519-27.
2010: Alexandre Hertig; Philippe Liere; Nathalie Chabbert-Buffet; Julie Fort; Antoine Pianos; Bernard Eychenne; Annie Cambourg; Michael Schumacher; Nadia Berkane; Guillaume Lefevre; Serge Uzan; Eric Rondeau; Patrick Rozenberg; Marie-Edith Rafestin-Oblin
Steroid profiling in preeclamptic women: evidence for aromatase deficiency.
American journal of obstetrics and gynecology 2010;203(5):477.e1-9.
2010: Jérôme Fagart; Alexander Hillisch; Jessica Huyet; Lars Bärfacker; Michel Fay; Ulrich Pleiss; Elisabeth Pook; Stefan Schäfer; Marie-Edith Rafestin-Oblin; Peter Kolkhof
A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule.
The Journal of biological chemistry 2010;285(39):29932-40.
2009: Isabelle Petit-Topin; Nathalie Turque; Jérôme Fagart; Michel Fay; André Ulmann; Erin Gainer; Marie-Edith Rafestin-Oblin
Met909 plays a key role in the activation of the progesterone receptor and also in the high potency of 13-ethyl progestins.
Molecular pharmacology 2009;75(6):1317-24.
2009: valerie leroy; Sophie de Seigneux; Victor Agassiz; Udo Hasler; Marie-Edith Rafestin-Oblin; Manlio Vinciguerra; Pierre-Yves Martin; Eric Féraille
Aldosterone activates NF-kappaB in the collecting duct.
Journal of the American Society of Nephrology : JASN 2009;20(1):131-44.
2007: Jessica Huyet; Grégory PINON; Michel R Fay; Jérôme Fagart; Marie-Edith Rafestin-Oblin
Structural basis of spirolactone recognition by the mineralocorticoid receptor.
Molecular pharmacology 2007;72(3):563-71.
2007: Armelle-Natsuo Takeda; Grégory PINON; Marcelle Bens; Jérôme Fagart; Marie-Edith Rafestin-Oblin; Alain Vandewalle
The synthetic androgen methyltrienolone (r1881) acts as a potent antagonist of the mineralocorticoid receptor.
Molecular pharmacology 2007;71(2):473-82.
2005: Jérôme Fagart; Jessica Huyet; Grégory PINON; Marina Rochel; Claudine MAYER; Marie-Edith Rafestin-Oblin
Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.
Nature structural & molecular biology 2005;12(6):554-5.
2005: Jérôme Fagart; Cendrine Seguin; Grégory PINON; Marie-Edith Rafestin-Oblin
The Met852 residue is a key organizer of the ligand-binding cavity of the human mineralocorticoid receptor.
Molecular pharmacology 2005;67(5):1714-22.
2005: Armin Sturm; Nicolas R Bury; L Dengreville; Jérôme Fagart; G Flouriot; Marie-Edith Rafestin-Oblin; Patrick Prunet
11-deoxycorticosterone is a potent agonist of the rainbow trout (Oncorhynchus mykiss) mineralocorticoid receptor.
Endocrinology 2005;146(1):47-55.
2004: Caroline Muller; Françoise Cluzeaud; Grégory PINON; Marie-Edith Rafestin-Oblin; Robert Morfin
Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor.
The Journal of steroid biochemistry and molecular biology 2004;92(5):469-76.
2004: Jérôme Fagart; Grégory PINON; Marie-Edith Rafestin-Oblin
[Agonists and antagonists of mineralocorticoids. The relation between structure and activity].
Annales de cardiologie et d'angéiologie 2004;53(3):154-7.
2004: Grégory PINON; Jérôme Fagart; Anny Souque; Gilles Auzou; Alain Vandewalle; Marie-Edith Rafestin-Oblin
Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension.
Molecular and cellular endocrinology 2004;217(1-2):181-8.
2004: Antoine Ouvrard-Pascaud; Stefania Puttini; Yannis Sainte-Marie; Rafika Athman; Virginie Fontaine; Françoise Cluzeaud; Nicolette Farman; Marie-Edith Rafestin-Oblin; Marcel Blot-Chabaud; Frederic Jaisser
Conditional gene expression in renal collecting duct epithelial cells: use of the inducible Cre-lox system.
American journal of physiology. Renal physiology 2004;286(1):F180-7.
2003: Nicolas R Bury; Armin Sturm; P Le Rouzic; Christèle Lethimonier; Bernadette Ducouret; Y Guiguen; M Robinson-Rechavi; Vincent Laudet; Marie-Edith Rafestin-Oblin; Patrick Prunet
Evidence for two distinct functional glucocorticoid receptors in teleost fish.
Journal of molecular endocrinology 2003;31(1):141-56.
2003: Brigitte Bocchi; Jérôme Fagart; Françoise Cluzeaud; Michèle Fay; Marie-Edith Rafestin-Oblin; Nicolette Farman
Glucocorticoid metabolism by 11-beta hydroxysteroid dehydrogenase type 2 modulates human mineralocorticoid receptor transactivation activity.
The Journal of steroid biochemistry and molecular biology 2003;84(2-3):239-44.
2003: Marie-Edith Rafestin-Oblin; Anny Souque; Brigitte Bocchi; Grégory PINON; Jérôme Fagart; Alain Vandewalle
The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.
Endocrinology 2003;144(2):528-33.
2002: Marie-Edith Rafestin-Oblin; Jérôme Fagart; Anny Souque; Cendrine Seguin; Marcelle Bens; Alain Vandewalle
11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.
Molecular pharmacology 2002;62(6):1306-13.
2001: Nicolette Farman; Marie-Edith Rafestin-Oblin
Multiple aspects of mineralocorticoid selectivity.
American journal of physiology. Renal physiology 2001;280(2):F181-92.
2000: Gilles Auzou; Jérôme Fagart; Anny Souque; C Hellal-Lévy; Jean-Marie Wurtz; Dino Moras; Marie-Edith Rafestin-Oblin
A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones.
Molecular pharmacology 2000;58(4):684-91.
2000: C Hellal-Levy; Jérôme Fagart; Anny Souque; Jean-Marie Wurtz; Dino Moras; Marie-Edith Rafestin-Oblin
Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor.
Molecular endocrinology (Baltimore, Md.) 2000;14(8):1210-21.
2000: C Hellal-Levy; Jérôme Fagart; Anny Souque; Marie-Edith Rafestin-Oblin
Mechanistic aspects of mineralocorticoid receptor activation.
Kidney international 2000;57(4):1250-5.
1999: C Hellal-Levy; B Couette; Jérôme Fagart; Anny Souque; C Gomez-Sanchez; Marie-Edith Rafestin-Oblin
Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors.
FEBS letters 1999;464(1-2):9-13.
1999: Marcelle Bens; Véronique Vallet; Françoise Cluzeaud; L Pascual-Letallec; Axel Kahn; Marie-Edith Rafestin-Oblin; Bernard C Rossier; Alain Vandewalle
Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line.
Journal of the American Society of Nephrology : JASN 1999;10(5):923-34.
1999: S Roux; Béatrice Térouanne; B Couette; Marie-Edith Rafestin-Oblin; Jean-Claude Nicolas
Conformational change in the human glucocorticoid receptor induced by ligand binding is altered by mutation of isoleucine 747 by a threonine.
The Journal of biological chemistry 1999;274(15):10059-65.
1999: C Hellal-Levy; Jérôme Fagart; Anny Souque; Marie-Edith Rafestin-Oblin
[Corticosteroid hormones: mechanisms involved in the recognition of aldosterone by mineralocorticoid receptors].
Journal de la Société de biologie 1999;193(4-5):355-60.
1998: Jérôme Fagart; B Couette; Anny Souque; Elisabeth Davioud; Andrée Marquet; Marie-Edith Rafestin-Oblin
Photoaffinity labelling of the human mineralocorticoid receptor with steroids having a reactive group at position 3, 18 or 21.
Biochimica et biophysica acta 1998;1388(1):35-44.
1998: Jérôme Fagart; Jean-Marie Wurtz; Anny Souque; C Hellal-Levy; Dino Moras; Marie-Edith Rafestin-Oblin
Antagonism in the human mineralocorticoid receptor.
The EMBO journal 1998;17(12):3317-25.
1998: B Couette; Stéphan Jalaguier; C Hellal-Levy; B Lupo; Jérôme Fagart; Gilles Auzou; Marie-Edith Rafestin-Oblin
Folding requirements of the ligand-binding domain of the human mineralocorticoid receptor.
Molecular endocrinology (Baltimore, Md.) 1998;12(6):855-63.
1998: Marie-Edith Rafestin-Oblin; B Couette
[Aldosterone receptors: new insights in hormonal signal transduction].
Thérapie 1998;53(3):227-35.
1998: Zahia Ouar; E Solé; Marcelle Bens; Marie-Edith Rafestin-Oblin; Anna Meseguer; Alain Vandewalle
Pleiotropic effects of dihydrotestosterone in immortalized mouse proximal tubule cells. Technical note.
Kidney international 1998;53(1):59-66.
1997: Stéphan Jalaguier; B Lupo; G Hugon; Marie-Edith Rafestin-Oblin; Gilles Auzou
Involvement of the N-terminal region of the human mineralocorticoid receptor hormone-binding domain in agonist and antagonist binding as revealed by a new monoclonal antibody.
The Biochemical journal 1997;324 ( Pt 1)():57-63.
1996: Elisabeth Davioud; Jérôme Fagart; Anny Souque; Marie-Edith Rafestin-Oblin; Andrée Marquet
New steroidal diazo ketones as potential photoaffinity labeling reagents for the mineralocorticoid receptor: synthesis and biological activities.
Journal of medicinal chemistry 1996;39(14):2860-4.
1996: B Couette; Jérôme Fagart; Stéphan Jalaguier; M Lombes; Anny Souque; Marie-Edith Rafestin-Oblin
Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure.
The Biochemical journal 1996;315 ( Pt 2)():421-7.
1996: Anny Souque; Jérôme Fagart; B Couette; Marie-Edith Rafestin-Oblin
Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor.
The Journal of steroid biochemistry and molecular biology 1996;57(5-6):315-21.
1995: Anny Souque; Jérôme Fagart; B Couette; Elisabeth Davioud; Franck Sobrio; Andrée Marquet; Marie-Edith Rafestin-Oblin
The mineralocorticoid activity of progesterone derivatives depends on the nature of the C18 substituent.
Endocrinology 1995;136(12):5651-8.
1994: B Couette; S Le Ricousse; D Fortin; Marie-Edith Rafestin-Oblin; H Richard-Foy
The establishment of the long terminal repeat of the mouse mammary tumor virus into CV-1 cells allows a functional analysis of steroid receptors.
Biochimica et biophysica acta 1994;1219(3):607-12.
1994: M Lombes; S Kenouch; Anny Souque; Nicolette Farman; Marie-Edith Rafestin-Oblin
The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogenase.
Endocrinology 1994;135(3):834-40.
1994: Marc Lombès; Nadine Binart; F Delahaye; Etienne Baulieu; Marie-Edith Rafestin-Oblin
Differential intracellular localization of human mineralocorticosteroid receptor on binding of agonists and antagonists.
The Biochemical journal 1994;302 ( Pt 1)():191-7.
1993: Alain Vandewalle; Marie-Edith Rafestin-Oblin; J Hagege; M Géniteau-Legendre; R Cassingéna; Pierre M Ronco
Phenotypic effects of aldosterone and dexamethasone in a SV40-transformed mammalian cortical ascending limb cell line exhibiting mineralocorticoid receptors.
Journal of cellular physiology 1993;156(2):383-94.
1993: Marie-Edith Rafestin-Oblin; Nicolette Farman; R Cassingena; P Ronco; Alain Vandewalle
Mineralocorticoid receptors in SV40-transformed tubule cell lines derived from rabbit kidney.
The Journal of steroid biochemistry and molecular biology 1993;44(1):45-52.
1992: B Couette; M Lombes; Etienne Baulieu; Marie-Edith Rafestin-Oblin
Aldosterone antagonists destabilize the mineralocorticosteroid receptor.
The Biochemical journal 1992;282 ( Pt 3)():697-702.
1992: Marie-Edith Rafestin-Oblin; M Lombes; B Couette; Etienne Baulieu
Differences between aldosterone and its antagonists in binding kinetics and ligand-induced hsp90 release from mineralocorticosteroid receptor.
The Journal of steroid biochemistry and molecular biology 1992;41(3-8):815-21.
1992: B Couette; V Marsaud; Etienne Baulieu; H Richard-Foy; Marie-Edith Rafestin-Oblin
Spironolactone, an aldosterone antagonist, acts as an antiglucocorticosteroid on the mouse mammary tumor virus promoter.
Endocrinology 1992;130(1):430-6.
1991: Nadine Binart; M Lombes; Marie-Edith Rafestin-Oblin; Etienne Baulieu
Characterization of human mineralocorticosteroid receptor expressed in the baculovirus system.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10681-5.
1991: Marie-Edith Rafestin-Oblin; B Couette; C Barlet-Bas; Lydie Cheval; A Viger; Alain Doucet
Renal action of progesterone and 18-substituted derivatives.
The American journal of physiology 1991;260(6 Pt 2):F828-32.
1990: Etienne Baulieu; Nadine Binart; Françoise Cadepond; Maria Grazia Catelli; Béatrice Chambraud; J Garnier; Jean-Marie Gasc; G Groyer-Schweizer; Marie-Edith Rafestin-Oblin; Christine Radanyi
Are receptor-associated nuclear proteins associated with the earliest effects of steroid hormones?
Revista española de fisiología 1990;46(1):17-29.
1990: Etienne Baulieu; Nadine Binart; Françoise Cadepond; Maria Grazia Catelli; Béatrice Chambraud; J Garnier; Jean-Marie Gasc; G Groyer-Schweizer; Marie-Edith Rafestin-Oblin; Christine Radanyi
Are receptor-associated nuclear proteins associated with the earliest effects of steroid hormones?
Symposia of the Society for Experimental Biology 1990;44():3-20.
1989: Marie-Edith Rafestin-Oblin; B Couette; Christine Radanyi; M Lombes; Etienne Baulieu
Mineralocorticosteroid receptor of the chick intestine. Oligomeric structure and transformation.
The Journal of biological chemistry 1989;264(16):9304-9.
1987: M Lombes; M Claire; Patrick Lustenberger; A Michaud; Marie-Edith Rafestin-Oblin
A new affinity matrix for mineralocorticoid receptors.
The Journal of biological chemistry 1987;262(17):8121-7.
1986: Marie-Edith Rafestin-Oblin; M Lombes; Patrick Lustenberger; P Blanchardie; A Michaud; G Cornu; M Claire
Affinity of corticosteroids for mineralocorticoid and glucocorticoid receptors of the rabbit kidney: effect of steroid substitution.
Journal of steroid biochemistry 1986;25(4):527-34.
1986: Marie-Edith Rafestin-Oblin; M Lombes; R Harrison; P Blanchardie; M Claire
Cross-reactivity of a monoclonal antiglucocorticoid receptor antibody BuGR1 with glucocorticoid and mineralocorticoid receptors of various species.
Journal of steroid biochemistry 1986;24(1):259-62.
1984: Marie-Edith Rafestin-Oblin; M Claire; M Lombes; A Michaud; P Corvol
Modulation of aldosterone receptors in rat kidney: effects of steroid treatment and potassium diet.
Journal of steroid biochemistry 1984;21(4):465-70.
1984: M Lombes; M Claire; M Pinto; A Michaud; Marie-Edith Rafestin-Oblin
Aldosterone binding in the human colon carcinoma cell line HT29: correlation with cell differentiation.
Journal of steroid biochemistry 1984;20(1):329-33.
1984: Marie-Edith Rafestin-Oblin; M Lombes; J B Michiel; A Michaud; M Claire
Mineralocorticoid receptors in the epithelial cells of human colon and ileum.
Journal of steroid biochemistry 1984;20(1):311-5.
1984: Bernard C Rossier; M Claire; Marie-Edith Rafestin-Oblin; H P Gaeggeler; Käthi Geering
Effects of thyroid hormones and aldosterone on mineralocorticoid binding sites in the toad bladder.
The Journal of membrane biology 1984;77(1):25-32.
1983: Bernard C Rossier; M Claire; Marie-Edith Rafestin-Oblin; Käthi Geering; H P Gäggeler; P Corvol
Binding and antimineralocorticoid activities of spirolactones in toad bladder.
The American journal of physiology 1983;244(1):C24-31.
1981: Marie-Edith Rafestin-Oblin; M Claire; A Michaud; P Corvol
Mineralocorticoid receptors during normal kidney growth and compensatory renal hypertrophy.
Journal of steroid biochemistry 1981;14(4):337-40.