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John Rafferty

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Amino Acid Sequences

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Publications

TOP 3
Robert C Salmon; John B Rafferty; Matthew J Cliff; David J Kelly
The CouPSTU and TarPQM transporters in Rhodopseudomonas palustris: redundant, promiscuous uptake systems for lignin-derived aromatic substrates.
Abd Ghani Abd Aziz; Patrick J Baker; Rahmah Mohamed; Sheila Nathan; John B Rafferty; Sergey N Ruzheinikov; Svetlana E Sedelnikova; Simon Thorpe; David Rice
Crystallization and preliminary X-ray analysis of the receiver domain of a putative response regulator, BPSL0128, from Burkholderia pseudomallei.
Avinash Kale; Chatchawal Phansopa; John B Rafferty; Chatrudee Suwannachart; C Jeremy Craven; David J Kelly
The virulence factor PEB4 (Cj0596) and the periplasmic protein Cj1289 are two structurally related SurA-like chaperones in the human pathogen Campylobacter jejuni.

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All Publications

2013: Robert C Salmon; John B Rafferty; Matthew J Cliff; David J Kelly
The CouPSTU and TarPQM transporters in Rhodopseudomonas palustris: redundant, promiscuous uptake systems for lignin-derived aromatic substrates.
PloS one 2013;8(3):e59844.
2012: Abd Ghani Abd Aziz; Patrick J Baker; Rahmah Mohamed; Sheila Nathan; John B Rafferty; Sergey N Ruzheinikov; Svetlana E Sedelnikova; Simon Thorpe; David Rice
Crystallization and preliminary X-ray analysis of the receiver domain of a putative response regulator, BPSL0128, from Burkholderia pseudomallei.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 8):917-22.
2011: Avinash Kale; Chatchawal Phansopa; John B Rafferty; Chatrudee Suwannachart; C Jeremy Craven; David J Kelly
The virulence factor PEB4 (Cj0596) and the periplasmic protein Cj1289 are two structurally related SurA-like chaperones in the human pathogen Campylobacter jejuni.
The Journal of biological chemistry 2011;286(24):21254-65.
2007: Stephen P Muench; Sean T Prigge; Rima McLeod; John B Rafferty; Michael J Kirisits; Craig William Roberts; Ernest J Mui; David Rice
Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 3):328-38.
2007: Anna Roujeinikova; William J Simon; John Gilroy; David Rice; John B Rafferty; Antoni R Slabas
Structural studies of fatty acyl-(acyl carrier protein) thioesters reveal a hydrophobic binding cavity that can expand to fit longer substrates.
Journal of molecular biology 2007;365(1):135-45.
2006: Rachel Macmaster; Svetlana E Sedelnikova; Patrick J Baker; Edward L Bolt; Robert G Lloyd; John B Rafferty
RusA Holliday junction resolvase: DNA complex structure--insights into selectivity and specificity.
Nucleic acids research 2006;34(19):5577-84.
2006: Paul Thaw; Svetlana E Sedelnikova; Tatyana A Muranova; Sebastian Wiese; Silvia Ayora; Juan C Alonso; Arie B Brinkman; Jasper Akerboom; John van der Oost; John B Rafferty
Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family.
Nucleic acids research 2006;34(5):1439-49.
2005: Natalie McGregor; Silvia Ayora; Svetlana E Sedelnikova; Begoña Carrasco; Juan C Alonso; Paul Thaw; John B Rafferty
The structure of Bacillus subtilis RecU Holliday junction resolvase and its role in substrate selection and sequence-specific cleavage.
Structure (London, England : 1993) 2005;13(9):1341-51.
2004: Mark J Dickman; Svetlana E Sedelnikova; John B Rafferty; David P Hornby
Rapid analysis of protein-nucleic acid complexes using MALDI TOF mass spectrometry and ion pair reverse phase liquid chromatography.
Journal of biochemical and biophysical methods 2004;58(1):39-48.
2003: John B Rafferty; Edward L Bolt; Tatyana A Muranova; Svetlana E Sedelnikova; Philip M Leonard; Alessandra Pasquo; Patrick J Baker; David Rice; Gary Sharples; Robert G Lloyd
The structure of Escherichia coli RusA endonuclease reveals a new Holliday junction DNA binding fold.
Structure (London, England : 1993) 2003;11(12):1557-67.
2003: Tatyana A Muranova; Svetlana E Sedelnikova; Philip M Leonard; Alessandra Pasquo; Edward L Bolt; Robert G Lloyd; John B Rafferty
Crystallization of RusA Holliday junction resolvase from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2262-4.
2003: Sandra Santos-Sierra; Marc Lemonnier; Belen Nuñez; David Hargreaves; John B Rafferty; Rafael Giraldo; José Manuel Andreu; Ramón Díaz-Orejas
Non-cytotoxic variants of the Kid protein that retain their auto-regulatory activity.
Plasmid 2003;50(2):120-30.
2003: Laura E Kehoe; Jaruwaree Snidwongse; Patrice Courvalin; John B Rafferty; Iain A Murray
Structural basis of Synercid (quinupristin-dalfopristin) resistance in Gram-positive bacterial pathogens.
The Journal of biological chemistry 2003;278(32):29963-70.
2003: Stephen P Muench; John B Rafferty; Rima McLeod; David Rice; Sean T Prigge
Expression, purification and crystallization of the Plasmodium falciparum enoyl reductase.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 7):1246-8.
2003: Scott Bailey; Svetlana E Sedelnikova; Pablo Mesa; Silvia Ayora; Juan C Alonso; John B Rafferty
Crystallization of the Bacillus subtilis SPP1 bacteriophage helicase loader protein G39P.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 6):1090-2.
2003: Scott Bailey; Svetlana E Sedelnikova; Pablo Mesa; Silvia Ayora; Jonathan P Waltho; Alison E Ashcroft; Andrew J Baron; Juan C Alonso; John B Rafferty
Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P.
The Journal of biological chemistry 2003;278(17):15304-12.
2003: Hend M Abdelghany; Scott Bailey; G Michael Blackburn; John B Rafferty; Alexander G McLennan
Analysis of the catalytic and binding residues of the diadenosine tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans by site-directed mutagenesis.
The Journal of biological chemistry 2003;278(7):4435-9.
2002: Antoni R Slabas; Johan Kroon; Ted P Scheirer; John Gilroy; Matthew W Hayman; David Rice; Andrew P Turnbull; John B Rafferty; Tony Fawcett; William J Simon
Squash glycerol-3-phosphate (1)-acyltransferase. Alteration of substrate selectivity and identification of arginine and lysine residues important in catalytic activity.
The Journal of biological chemistry 2002;277(46):43918-23.
2002: Mark J Dickman; Stuart M Ingleston; Svetlana E Sedelnikova; John B Rafferty; Robert G Lloyd; Jane A Grasby; David P Hornby
The RuvABC resolvasome.
European journal of biochemistry / FEBS 2002;269(22):5492-501.
2002: Thijs J G Ettema; Arie B Brinkman; Travis H Tani; John B Rafferty; John van der Oost
A novel ligand-binding domain involved in regulation of amino acid metabolism in prokaryotes.
The Journal of biological chemistry 2002;277(40):37464-8.
2002: David Hargreaves; Sandra Santos-Sierra; Rafael Giraldo; Rosario Sabariegos-Jareño; Guillermo de la Cueva-Méndez; Rolf Boelens; Ramón Díaz-Orejas; John B Rafferty
Structural and functional analysis of the kid toxin protein from E. coli plasmid R1.
Structure (London, England : 1993) 2002;10(10):1425-33.
2002: Anna Roujeinikova; Clair Baldock; William J Simon; John Gilroy; Patrick J Baker; Antoine R Stuitje; David Rice; Antoni R Slabas; John B Rafferty
X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site.
Structure (London, England : 1993) 2002;10(6):825-35.
2002: Scott Bailey; Svetlana E Sedelnikova; G Michael Blackburn; Hend M Abdelghany; Patrick J Baker; Alexander G McLennan; John B Rafferty
The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms.
Structure (London, England : 1993) 2002;10(4):589-600.
2002: Scott Bailey; Svetlana E Sedelnikova; G Michael Blackburn; Hend M Abdelghany; Alexander G McLennan; John B Rafferty
Crystallization of a complex of Caenorhabditis elegans diadenosine tetraphosphate hydrolase and a non-hydrolysable substrate analogue, AppCH2ppA.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 3):526-8.
2002: David Hargreaves; Rafael Giraldo; Sandra Santos-Sierra; Rolf Boelens; David Rice; Ramón Díaz-Orejas; John B Rafferty
Crystallization and preliminary X-ray crystallographic studies on the parD-encoded protein Kid from Escherichia coli plasmid R1.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 2):355-8.
2002: Anna Roujeinikova; Clair Baldock; William J Simon; John Gilroy; Patrick J Baker; Antoine R Stuitje; David Rice; John B Rafferty; Antoni R Slabas
Crystallization and preliminary X-ray crystallographic studies on acyl-(acyl carrier protein) from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 2):330-2.
2001: Hend M Abdelghany; Lakhdar Gasmi; Jared L Cartwright; Scott Bailey; John B Rafferty; Alexander G McLennan
Cloning, characterisation and crystallisation of a diadenosine 5',5"'-P(1),P(4)-tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans.
Biochimica et biophysica acta 2001;1550(1):27-36.
2001: Svetlana E Sedelnikova; S H Smits; Philip M Leonard; Arie B Brinkman; John van der Oost; John B Rafferty; David Rice
Crystallization and quaternary structure analysis of an Lrp-like regulatory protein from the hyperthermophile Pyrococcus furiosus.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 6):886-8.
2001: Colin W Levy; Clair Baldock; AJ Wallace; Svetlana E Sedelnikova; Russell Viner; J M Clough; Antoine R Stuitje; Antoni R Slabas; David Rice; John B Rafferty
A study of the structure-activity relationship for diazaborine inhibition of Escherichia coli enoyl-ACP reductase.
Journal of molecular biology 2001;309(1):171-80.
2001: Andrew P Turnbull; John B Rafferty; Svetlana E Sedelnikova; Antoni R Slabas; T P Schierer; Johan Kroon; JW Simon; Tony Fawcett; I Nishida; Norio Murata; David Rice
Analysis of the structure, substrate specificity, and mechanism of squash glycerol-3-phosphate (1)-acyltransferase.
Structure (London, England : 1993) 2001;9(5):347-53.
2001: Philip M Leonard; S H Smits; Svetlana E Sedelnikova; Arie B Brinkman; WILLEM DE VOS; John van der Oost; David Rice; John B Rafferty
Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus.
The EMBO journal 2001;20(5):990-7.
2001: Andrew P Turnbull; John B Rafferty; Svetlana E Sedelnikova; Antoni R Slabas; T P Schierer ; Johan Kroon; I Nishida; Norio Murata; JW Simon; David Rice
Crystallization and preliminary X-ray analysis of the glycerol-3-phosphate 1-acyltransferase from squash (Cucurbita moschata).
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 3):451-3.
2001: Rima McLeod; Stephen P Muench; John B Rafferty; Dennis E Kyle; Ernest J Mui; Michael J Kirisits; Doug Mack; Craig William Roberts; Benjamin Udayakumar Samuel; Russell E Lyons; M Dorris; Wilbur K Milhous; David Rice
Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.
International journal for parasitology 2001;31(2):109-13.
2000: Matthew W Hayman; Tony Fawcett; T F Schierer; JW Simon; Johan Kroon; John Gilroy; David Rice; John B Rafferty; Andrew P Turnbull; Svetlana E Sedelnikova; Antoni R Slabas
Mutagenesis of squash (Cucurbita moschata) glycerol-3-phosphate acyltransferase (GPAT) to produce an enzyme with altered substrate selectivity.
Biochemical Society transactions 2000;28(6):680-1.
2000: Antoni R Slabas; W R Simon; T Schierer; Johan Kroon; Tony Fawcett; Matthew W Hayman; John Gilroy; I Nishida; Norio Murata; John B Rafferty; Andrew P Turnbull; David Rice
Plant glycerol-3-phosphate-1-acyltransferase (GPAT): structure selectivity studies.
Biochemical Society transactions 2000;28(6):677-9.
2000: Martin Fisher; Johan Kroon; W Martindale; Antoine R Stuitje; Antoni R Slabas; John B Rafferty
The X-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis.
Structure (London, England : 1993) 2000;8(4):339-47.
2000: Martin Fisher; Svetlana E Sedelnikova; W Martindale; N C Thomas; JW Simon; Antoni R Slabas; John B Rafferty
Crystallization of the NADP-dependent beta-keto acyl-carrier protein reductase from Brassica napus.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 1):86-8.
1999: Anna Roujeinikova; Colin W Levy; Siân Rowsell; Svetlana E Sedelnikova; Patrick J Baker; Claire A Minshull; A Mistry; Jeremy G Colls; R Camble; Antoine R Stuitje; Antoni R Slabas; John B Rafferty; Richard A Pauptit; Russell Viner; David Rice
Crystallographic analysis of triclosan bound to enoyl reductase.
Journal of molecular biology 1999;294(2):527-35.
1999: Anna Roujeinikova; Svetlana E Sedelnikova; GJ de Boer; Antoine R Stuitje; Antoni R Slabas; John B Rafferty; David Rice
Inhibitor binding studies on enoyl reductase reveal conformational changes related to substrate recognition.
The Journal of biological chemistry 1999;274(43):30811-7.
1999: Colin W Levy; Anna Roujeinikova; Svetlana E Sedelnikova; Patrick J Baker; Antoine R Stuitje; Antoni R Slabas; David Rice; John B Rafferty
Molecular basis of triclosan activity.
Nature 1999;398(6726):383-4.
1999: David Hargreaves; John B Rafferty; Svetlana E Sedelnikova; Robert G Lloyd; David Rice
Crystallization of Escherichia coli RuvA complexed with a synthetic Holliday junction.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 1):263-5.
1999: GJ de Boer; G J Pielage; H John J Nijkamp; Antoni R Slabas; John B Rafferty; Clair Baldock; David Rice; Antoine R Stuitje
Molecular genetic analysis of enoyl-acyl carrier protein reductase inhibition by diazaborine.
Molecular microbiology 1999;31(2):443-50.
1998: Clair Baldock; John B Rafferty; Antoine R Stuitje; Antoni R Slabas; David Rice
The X-ray structure of Escherichia coli enoyl reductase with bound NAD+ at 2.1 A resolution.
Journal of molecular biology 1998;284(5):1529-46.
1998: David Hargreaves; David Rice; Svetlana E Sedelnikova; Peter J Artymiuk; Robert G Lloyd; John B Rafferty
Crystal structure of E.coli RuvA with bound DNA Holliday junction at 6 A resolution.
Nature structural biology 1998;5(6):441-6.
1998: Clair Baldock; GJ de Boer; John B Rafferty; Antoine R Stuitje; David Rice
Mechanism of action of diazaborines.
Biochemical pharmacology 1998;55(10):1541-9.
1998: John B Rafferty; Martin Fisher; Sean Langridge; W Martindale; N C Thomas; JW Simon; S Bithell; Antoni R Slabas; David Rice
Crystallization of the NADP-dependent beta-keto acyl carrier protein reductase from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 3):427-9.
1998: John B Rafferty; Stuart M Ingleston; David Hargreaves; Peter J Artymiuk; Gary Sharples; Robert G Lloyd; David Rice
Structural similarities between Escherichia coli RuvA protein and other DNA-binding proteins and a mutational analysis of its binding to the holliday junction.
Journal of molecular biology 1998;278(1):105-16.
1997: David Rice; John B Rafferty; Peter J Artymiuk; Robert G Lloyd
Insights into the mechanisms of homologous recombination from the structure of RuvA.
Current opinion in structural biology 1997;7(6):798-803.
1997: Svetlana E Sedelnikova; John B Rafferty; David Hargreaves; Akeel A Mahdi; Robert G Lloyd; David Rice
Crystallization of E. coli RuvA gives insights into the symmetry of a Holliday junction/protein complex.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 1):122-4.
1996: Clair Baldock; John B Rafferty; Svetlana E Sedelnikova; Patrick J Baker; Antoine R Stuitje; Antoni R Slabas; T R Hawkes; David Rice
A mechanism of drug action revealed by structural studies of enoyl reductase.
Science (New York, N.Y.) 1996;274(5295):2107-10.
1996: Clair Baldock; John B Rafferty; Svetlana E Sedelnikova; S Bithell; Antoine R Stuitje; Antoni R Slabas; David Rice
Crystallization of Escherichia coli enoyl reductase and its complex with diazaborine.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 6):1181-4.
1996: John B Rafferty; Svetlana E Sedelnikova; David Hargreaves; Peter J Artymiuk; Patrick J Baker; Gary Sharples; A A Mahdi; Robert G Lloyd; David Rice
Crystal structure of DNA recombination protein RuvA and a model for its binding to the Holliday junction.
Science (New York, N.Y.) 1996;274(5286):415-21.
1995: John B Rafferty; JW Simon; Clair Baldock; Peter J Artymiuk; Patrick J Baker; Antoine R Stuitje; Antoni R Slabas; David Rice
Common themes in redox chemistry emerge from the X-ray structure of oilseed rape (Brassica napus) enoyl acyl carrier protein reductase.
Structure (London, England : 1993) 1995;3(9):927-38.
1994: John B Rafferty; JW Simon; Antoine R Stuitje; Antoni R Slabas; T Fawcett; David Rice
Crystallization of the NADH-specific enoyl acyl carrier protein reductase from Brassica napus.
Journal of molecular biology 1994;237(2):240-2.