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Carlo Rago

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Kajsa Ericson; Christine Gan; Ian Cheong; Carlo Rago; Yardena Samuels; Victor E Velculescu; Kenneth W Kinzler; David L Huso; Bert Vogelstein; Nickolas Papadopoulos
Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.
Jihye Yun; Carlo Rago; Ian Cheong; Ray Pagliarini; Philipp Angenendt; Harith Rajagopalan; Kerstin Schmidt; James Willson; Sanford Markowitz; Shibin Zhou; Luis Alberto Diaz; Victor E Velculescu; Christoph Lengauer; Kenneth W Kinzler; Bert Vogelstein; Nickolas Papadopoulos
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Surojit Sur; Raymond Pagliarini; Fred Bunz; Carlo Rago; Luis Alberto Diaz; Kenneth W Kinzler; Bert Vogelstein; Nickolas Papadopoulos
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53.

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All Publications

2010: Kajsa Ericson; Christine Gan; Ian Cheong; Carlo Rago; Yardena Samuels; Victor E Velculescu; Kenneth W Kinzler; David L Huso; Bert Vogelstein; Nickolas Papadopoulos
Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(6):2598-603.
2009: Jihye Yun; Carlo Rago; Ian Cheong; Ray Pagliarini; Philipp Angenendt; Harith Rajagopalan; Kerstin Schmidt; James Willson; Sanford Markowitz; Shibin Zhou; Luis Alberto Diaz; Victor E Velculescu; Christoph Lengauer; Kenneth W Kinzler; Bert Vogelstein; Nickolas Papadopoulos
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Science (New York, N.Y.) 2009;325(5947):1555-9.
2009: Surojit Sur; Raymond Pagliarini; Fred Bunz; Carlo Rago; Luis Alberto Diaz; Kenneth W Kinzler; Bert Vogelstein; Nickolas Papadopoulos
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3964-9.
2008: Tomas Hucl; Carlo Rago; Eike Gallmeier; Jonathan R Brody; Myriam Gorospe; Scott E Kern
A syngeneic variance library for functional annotation of human variation: application to BRCA2.
Cancer research 2008;68(13):5023-30.
2007: Carlo Rago; David L Huso; Frank Diehl; Baktiar O Karim; Guosheng Liu; Nickolas Papadopoulos; Yardena Samuels; Victor E Velculescu; Bert Vogelstein; Kenneth W Kinzler; Luis Alberto Diaz
Serial assessment of human tumor burdens in mice by the analysis of circulating DNA.
Cancer research 2007;67(19):9364-70.
2007: Carlo Rago; Bert Vogelstein; Fred Bunz
Genetic knockouts and knockins in human somatic cells.
Nature protocols 2007;2(11):2734-46.
2006: Eike Gallmeier; Eric S Calhoun; Carlo Rago; Jonathan R Brody; Steven C Cunningham; Tomas Hucl; Myriam Gorospe; Manu Kohli; Christoph Lengauer; Scott E Kern
Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options.
Gastroenterology 2006;130(7):2145-54.
2006: Duyen T Dang; Fang Chen; Lawrence B Gardner; Jordan M Cummins; Carlo Rago; Fred Bunz; Sergey V Kantsevoy; Long H Dang
Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts.
Cancer research 2006;66(3):1684-936.
2005: Duyen T Dang; Fang Chen; Manu Kohli; Carlo Rago; Jordan M Cummins; Long H Dang
Glutathione S-transferase pi1 promotes tumorigenicity in HCT116 human colon cancer cells.
Cancer research 2005;65(20):9485-94.
2005: Yardena Samuels; Luis Alberto Diaz; Oleg Schmidt-Kittler; Jordan M Cummins; Laura Delong; Ian Cheong; Carlo Rago; David L Huso; Christoph Lengauer; Kenneth W Kinzler; Bert Vogelstein; Victor E Velculescu
Mutant PIK3CA promotes cell growth and invasion of human cancer cells.
Cancer cell 2005;7(6):561-73.
2004: Jordan M Cummins; Manu Kohli; Carlo Rago; Kenneth W Kinzler; Bert Vogelstein; Fred Bunz
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells.
Cancer research 2004;64(9):3006-8.
2004: Jordan M Cummins; Carlo Rago; Manu Kohli; Kenneth W Kinzler; Christoph Lengauer; Bert Vogelstein
Tumour suppression: disruption of HAUSP gene stabilizes p53.
Nature 2004;428(6982):1 p following 486.
2004: Harith Rajagopalan; Prasad V Jallepalli; Carlo Rago; Victor E Velculescu; Kenneth W Kinzler; Bert Vogelstein; Christoph Lengauer
Inactivation of hCDC4 can cause chromosomal instability.
Nature 2004;428(6978):77-81.
2004: Manu Kohli; Carlo Rago
An efficient method for generating human somatic cell gene knockouts.
Discovery medicine 2004;4(20):37-40.
2004: Manu Kohli; Carlo Rago; Christoph Lengauer; Kenneth W Kinzler; Bert Vogelstein
Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses.
Nucleic acids research 2004;32(1):e3.
2002: Saurabh Saha; Andrew B Sparks; Carlo Rago; Viatcheslav Akmaev; Clarence J Wang; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu
Using the transcriptome to annotate the genome.
Nature biotechnology 2002;20(5):508-12.
2002: Tian-Li Wang; Carlo Rago; Natalie Silliman; Janine Ptak; Sanford Markowitz; James Willson; Giovanni Parmigiani; Kenneth W Kinzler; Bert Vogelstein; Victor E Velculescu
Prevalence of somatic alterations in the colorectal cancer cell genome.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3076-80.
2001: Saurabh Saha; Alberto Bardelli; Phillip Buckhaults; Victor E Velculescu; Carlo Rago; Brad St Croix; Katharine E Romans; Michael A Choti; Christoph Lengauer; Kenneth W Kinzler; Bert Vogelstein
A phosphatase associated with metastasis of colorectal cancer.
Science (New York, N.Y.) 2001;294(5545):1343-6.
2001: PAUL HWANG; Fred Bunz; J Yu; Carlo Rago; Timothy Chan; M P Murphy; G F Kelso; R A Smith; Kenneth W Kinzler; Bert Vogelstein
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells.
Nature medicine 2001;7(10):1111-7.
2001: Phillip Buckhaults; Carlo Rago; Brad St Croix; Katharine E Romans; Saurabh Saha; Lin Zhang; Bert Vogelstein; Kenneth W Kinzler
Secreted and cell surface genes expressed in benign and malignant colorectal tumors.
Cancer research 2001;61(19):6996-7001.
2000: Brad St Croix; Carlo Rago; Victor E Velculescu; Giovanni Traverso; Katharine E Romans; Elizabeth Montgomery; A Lal; Gregory J Riggins; Christoph Lengauer; Bert Vogelstein; Kenneth W Kinzler
Genes expressed in human tumor endothelium.
Science (New York, N.Y.) 2000;289(5482):1197-202.
2000: H Hermeking; Carlo Rago; M Schuhmacher; Q Li; J F Barrett; Alvaro J Obaya; Brenda C. O'Connell; Maria K Mateyak; W Tam; Franz Kohlhuber; Chi Dang; John M Sedivy; Dirk Eick; Bert Vogelstein; Kenneth W Kinzler
Identification of CDK4 as a target of c-MYC.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2229-34.
1999: J Yu; Lin Zhang; PAUL HWANG; Carlo Rago; Kenneth W Kinzler; Bert Vogelstein
Identification and classification of p53-regulated genes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14517-22.
1999: Victor E Velculescu; S L Madden; Lin Zhang; Alex E Lash; J Yu; Carlo Rago; A Lal; C J Wang; GA Beaudry; K M Ciriello; Brian P Cook; Michael R Dufault; AT Ferguson; Y Gao; Tong-Chuan He; H Hermeking; S K Hiraldo; PAUL HWANG; M A Lopez; H F Luderer; B Mathews; Joseph Petroziello; Kornelia Polyak; L Zawel; Kenneth W Kinzler
Analysis of human transcriptomes.
Nature genetics 1999;23(4):387-8.
1998: Tong-Chuan He; Andrew B Sparks; Carlo Rago; H Hermeking; L Zawel; LT da Costa; Patrice J Morin; Bert Vogelstein; Kenneth W Kinzler
Identification of c-MYC as a target of the APC pathway.
Science (New York, N.Y.) 1998;281(5382):1509-12.