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Laura Ragona

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Procedures

Living Beings

Phenomena

Physiology

Protein Folding

Anatomy

Livers

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Publications

TOP 3
Simona Tomaselli; Serena Zanzoni; Michael Assfalg; Clelia Cogliati; Henriette Molinari; Katiuscia Pagano; Laura Ragona
A disulfide bridge allows for site-selective binding in liver bile acid binding protein thereby stabilising the orientation of key amino acid side chains.
Katiuscia Pagano; Marco Presta; Antonella Bugatti; Giorgio Colombo; Chiara Foglieni; MARCO RUSNATI; Giulia Taraboletti; Simona Tomaselli; Rubben Torella; Lucia Zetta; Laura Ragona
Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule.
Ivano Eberini; Andrew Emerson; Elisabetta Gianazza; Alessandro Pedretti; Laura Ragona; Piero Ricchiuto; Cristina Sensi; Anna Tramontano
Simulation of urea-induced protein unfolding: a lesson from bovine β-lactoglobulin.

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All Publications

2012: Simona Tomaselli; Serena Zanzoni; Michael Assfalg; Clelia Cogliati; Henriette Molinari; Katiuscia Pagano; Laura Ragona
A disulfide bridge allows for site-selective binding in liver bile acid binding protein thereby stabilising the orientation of key amino acid side chains.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(10):2857-66.
2012: Katiuscia Pagano; Marco Presta; Antonella Bugatti; Giorgio Colombo; Chiara Foglieni; MARCO RUSNATI; Giulia Taraboletti; Simona Tomaselli; Rubben Torella; Lucia Zetta; Laura Ragona
Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule.
PloS one 2012;7(5):e36990.
2011: Ivano Eberini; Andrew Emerson; Elisabetta Gianazza; Alessandro Pedretti; Laura Ragona; Piero Ricchiuto; Cristina Sensi; Anna Tramontano
Simulation of urea-induced protein unfolding: a lesson from bovine β-lactoglobulin.
Journal of molecular graphics & modelling 2011;30():24-30.
2008: Ivano Eberini; Alessandro Guerini Rocco; Anna Rita Ientile; António M Baptista; Elisabetta Gianazza; Simona Tomaselli; Henriette Molinari; Laura Ragona
Conformational and dynamics changes induced by bile acids binding to chicken liver bile acid binding protein.
Proteins 2008;71(4):1889-98.
2008: Mara Guariento; Domenico Raimondo; Michael Assfalg; Serena Zanzoni; Patrizia Pesente; Laura Ragona; Anna Tramontano; Henriette Molinari
Identification and functional characterization of the bile acid transport proteins in non-mammalian ileum and mammalian liver.
Proteins 2008;70(2):462-72.
2007: Tommaso Eliseo; Laura Ragona; Maddalena Catalano; Michael Assfalg; Maurizio Paci; Lucia Zetta; Henriette Molinari; Daniel O Cicero
Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR.
Biochemistry 2007;46(44):12557-67.
2007: Michael Assfalg; Eliana Gianolio; Serena Zanzoni; Simona Tomaselli; Vito Lo Russo; Claudia Cabella; Laura Ragona; Silvio Aime; Henriette Molinari
NMR structural studies of the supramolecular adducts between a liver cytosolic bile acid binding protein and gadolinium(III)-chelates bearing bile acids residues: molecular determinants of the binding of a hepatospecific magnetic resonance imaging contrast agent.
Journal of medicinal chemistry 2007;50(22):5257-68.
2007: Simona Tomaselli; Laura Ragona; Lucia Zetta; Michael Assfalg; Pasquale Ferranti; Renato Longhi; Alexandre Bonvin; Henriette Molinari
NMR-based modeling and binding studies of a ternary complex between chicken liver bile acid binding protein and bile acids.
Proteins 2007;69(1):177-91.
2007: Stefano Capaldi; Massimiliano Perduca; Beniamino Faggion; Maria E Carrizo; Aldo Tava; Laura Ragona; Hugo L Monaco
Crystal structure of the anticarcinogenic Bowman-Birk inhibitor from snail medic (Medicago scutellata) seeds complexed with bovine trypsin.
Journal of structural biology 2007;158(1):71-9.
2006: Laura Ragona; Maddalena Catalano; Marianna Luppi; Daniel O Cicero; Tommaso Eliseo; Jefferson Foote; Federico Fogolari; Lucia Zetta; Henriette Molinari
NMR dynamic studies suggest that allosteric activation regulates ligand binding in chicken liver bile acid-binding protein.
The Journal of biological chemistry 2006;281(14):9697-709.
2005: Laura Ragona; Giorgio Colombo; Maddalena Catalano; Henriette Molinari
Determinants of protein stability and folding: comparative analysis of beta-lactoglobulins and liver basic fatty acid binding protein.
Proteins 2005;61(2):366-76.
2005: Federico Fogolari; Elisabetta Moroni; Marek Wojciechowski; Maciej Baginski; Laura Ragona; Henriette Molinari
MM/PBSA analysis of molecular dynamics simulations of bovine beta-lactoglobulin: free energy gradients in conformational transitions?
Proteins 2005;59(1):91-103.
2005: Laura D'Alfonso; Maddalena Collini; Laura Ragona; Raffaella Ugolini; Giancarlo Baldini; Henriette Molinari
Porcine beta-lactoglobulin chemical unfolding: identification of a non-native alpha-helical intermediate.
Proteins 2005;58(1):70-9.
2004: Giordano Invernizzi; Laura Ragona; Stefania Brocca; Eros Pedrazzoli; Henriette Molinari; Piero Morandini; Maddalena Catalano; Marina Lotti
Heterologous expression of bovine and porcine beta-lactoglobulins in Pichia pastoris: towards a comparative functional characterisation.
Journal of biotechnology 2004;109(1-2):169-78.
2004: Annalisa Lanza; Aldo Tava; Maddalena Catalano; Laura Ragona; Ilaria Singuaroli; Francesco Saverio Robustelli della Cuna; Gioacchino Robustelli Della Cuna
Effects of the Medicago scutellata trypsin inhibitor (MsTI) on cisplatin-induced cytotoxicity in human breast and cervical cancer cells.
Anticancer research 2004;24(1):227-33.
2003: Silvia Romagnoli; Federico Fogolari; Maddalena Catalano; Lucia Zetta; Gerhard Schaller; Konrad Urech; Matteo Giannattasio; Laura Ragona; Henriette Molinari
NMR solution structure of viscotoxin C1 from Viscum album species Coloratum ohwi: toward a structure-function analysis of viscotoxins.
Biochemistry 2003;42(43):12503-10.
2003: Laura Ragona; Federico Fogolari; Maddalena Catalano; Raffaella Ugolini; Lucia Zetta; Henriette Molinari
EF loop conformational change triggers ligand binding in beta-lactoglobulins.
The Journal of biological chemistry 2003;278(40):38840-6.
2003: Maddalena Collini; Laura D'Alfonso; Henriette Molinari; Laura Ragona; Maddalena Catalano; Giancarlo Baldini
Competitive binding of fatty acids and the fluorescent probe 1-8-anilinonaphthalene sulfonate to bovine beta-lactoglobulin.
Protein science : a publication of the Protein Society 2003;12(8):1596-603.
2003: Maddalena Catalano; Laura Ragona; Henriette Molinari; Aldo Tava; Lucia Zetta
Anticarcinogenic Bowman Birk inhibitor isolated from snail medic seeds (Medicago scutellata): solution structure and analysis of self-association behavior.
Biochemistry 2003;42(10):2836-46.
2003: Francesca Vasile; Laura Ragona; Maddalena Catalano; Lucia Zetta; Massimiliano Perduca; Hugo L Monaco; Henriette Molinari
Solution structure of chicken liver basic fatty acid binding protein.
Journal of biomolecular NMR 2003;25(2):157-60.
2002: Laura Ragona; Maddalena Catalano; Lucia Zetta; Renato Longhi; Federico Fogolari; Henriette Molinari
Peptide models of folding initiation sites of bovine beta-lactoglobulin: identification of nativelike hydrophobic interactions involving G and H strands.
Biochemistry 2002;41(8):2786-96.
2001: Raffaella Ugolini; Laura Ragona; E Silletti; Federico Fogolari; Ronald W Visschers; Arno C Alting; Henriette Molinari
Dimerization, stability and electrostatic properties of porcine beta-lactoglobulin.
European journal of biochemistry / FEBS 2001;268(16):4477-88.
2000: Silvia Romagnoli; Raffaella Ugolini; Federico Fogolari; Gerhard Schaller; Konrad Urech; Matteo Giannattasio; Laura Ragona; Henriette Molinari
NMR structural determination of viscotoxin A3 from Viscum album L.
The Biochemical journal 2000;350 Pt 2():569-77.
2000: Laura Ragona; Federico Fogolari; Lucia Zetta; D M Pérez; P Puyol; KG De Kruif; F Löhr; H Rüterjans; Henriette Molinari
Bovine beta-lactoglobulin: interaction studies with palmitic acid.
Protein science : a publication of the Protein Society 2000;9(7):1347-56.
2000: Federico Fogolari; Laura Ragona; S Licciardi; Silvia Romagnoli; R Michelutti; Raffaella Ugolini; Henriette Molinari
Electrostatic properties of bovine beta-lactoglobulin.
Proteins 2000;39(4):317-30.
1999: Laura Ragona; Federico Fogolari; Silvia Romagnoli; Lucia Zetta; J L Maubois; Henriette Molinari
Unfolding and refolding of bovine beta-lactoglobulin monitored by hydrogen exchange measurements.
Journal of molecular biology 1999;293(4):953-69.
1999: Laura Ragona; L Confalonieri; Lucia Zetta; KG De Kruif; Stefano Mammi; Evaristo Peggion; Renato Longhi; Henriette Molinari
Equilibrium unfolding CD studies of bovine beta-lactoglobulin and its 14-52 fragment at acidic pH.
Biopolymers 1999;49(6):441-50.
1998: Federico Fogolari; Laura Ragona; Lucia Zetta; Silvia Romagnoli; KG De Kruif; Henriette Molinari
Monomeric bovine beta-lactoglobulin adopts a beta-barrel fold at pH 2.
FEBS letters 1998;436(2):149-54.
1997: Maria Scarselli; A Facchiano; G Russo; Henriette Molinari; Laura Ragona; Lucia Zetta; Neri Niccolai
The design of a specific ligand of HIV gp120.
Journal of peptide science : an official publication of the European Peptide Society 1997;3(5):383-90.
1997: Henriette Molinari; G Esposito; Laura Ragona; M Pegna; Neri Niccolai; R M Brunne; A M Lesk; Lucia Zetta
Probing protein structure by solvent perturbation of NMR spectra: the surface accessibility of bovine pancreatic trypsin inhibitor.
Biophysical journal 1997;73(1):382-96.
1997: Laura Ragona; F Pusterla; Lucia Zetta; Hugo L Monaco; Henriette Molinari
Identification of a conserved hydrophobic cluster in partially folded bovine beta-lactoglobulin at pH 2.
Folding & design 1997;2(5):281-90.
1996: Laura Ragona; Henriette Molinari; Lucia Zetta; Renato Longhi; Daniela Marchini; Romano Dallai; L F Bernini; Luisa Lozzi; Maria Scarselli; Neri Niccolai
CD and NMR structural characterization of ceratotoxins, natural peptides with antimicrobial activity.
Biopolymers 1996;39(5):653-64.
1996: Henriette Molinari; Laura Ragona; test testing; G Musco; Roberto Consonni; Lucia Zetta; H L Monaco
Partially folded structure of monomeric bovine beta-lactoglobulin.
FEBS letters 1996;381(3):237-43.
1996: Roberto Consonni; R Limiroli; Renato Longhi; E Manera; G Vecchio; Laura Ragona; Antonio Siccardi; Lucia Zetta
NMR and CD studies on the conformation of a synthetic peptide containing epitopes of the human immunodeficiency virus 1 transmembrane protein gp41.
Biopolymers 1996;38(3):423-35.