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Stephen Ragsdale

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
23
Seravalli, Javier
8
Horng, Yih-Chern
7
Doukov, Tzanko
5
Dey, Mishtu
5
Kunz, Ryan
4
Murakami, E
4
Brunold, Thomas
4
Becker, Donald
4
Drennan, Catherine
4
Ferry, James
3
Feinberg, Benjamin
3
Furdui, Cristina
3
Banerjee, Ruma
3
Craft, Jennifer
3
Cramer, Stephen

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Publications

TOP 3
Lazarus Oliver; Woolerton Thomas W; Parkin Alison; Lukey Michael J; Reisner Erwin; Seravalli Javier; Pierce Elizabeth; Ragsdale Stephen W; Sargent Frank; Armstrong Fraser A
Water-gas shift reaction catalyzed by redox enzymes on conducting graphite platelets.
Kung Yan; Doukov Tzanko I; Seravalli Javier; Ragsdale Stephen W; Drennan Catherine L
Crystallographic snapshots of cyanide- and water-bound C-clusters from bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
Ragsdale Stephen W
Nickel-based Enzyme Systems.

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All Publications

2009: Lazarus Oliver; Woolerton Thomas W; Parkin Alison; Lukey Michael J; Reisner Erwin; Seravalli Javier; Pierce Elizabeth; Ragsdale Stephen W; Sargent Frank; Armstrong Fraser A
Water-gas shift reaction catalyzed by redox enzymes on conducting graphite platelets.
Journal of the American Chemical Society 2009;131(40):14154-5.
2009: Kung Yan; Doukov Tzanko I; Seravalli Javier; Ragsdale Stephen W; Drennan Catherine L
Crystallographic snapshots of cyanide- and water-bound C-clusters from bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
Biochemistry 2009;48(31):7432-40.
2009: Ragsdale Stephen W
Nickel-based Enzyme Systems.
The Journal of biological chemistry 2009;284(28):18571-5.
2009: Sarangi Ritimukta; Dey Mishtu; Ragsdale Stephen W
Geometric and electronic structures of the Ni(I) and methyl-Ni(III) intermediates of methyl-coenzyme M reductase.
Biochemistry 2009;48(14):3146-56.
2008: Ragsdale Stephen W; Pierce Elizabeth
Acetogenesis and the Wood-Ljungdahl pathway of CO(2) fixation.
Biochimica et biophysica acta 2008;1784(12):1873-98.
2008: Gupta Nirupama; Ragsdale Stephen W
Dual roles of an essential cysteine residue in activity of a redox-regulated bacterial transcriptional activator.
The Journal of biological chemistry 2008;283(42):28721-8.
2008: Pierce Elizabeth; Xie Gary; Barabote Ravi D; Saunders Elizabeth; Han Cliff S; Detter John C; Richardson Paul; Brettin Thomas S; Das Amaresh; Ljungdahl Lars G; Ragsdale Stephen W
The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum).
Environmental microbiology 2008;10(10):2550-73.
2008: Seravalli Javier; Ragsdale Stephen W
13C NMR characterization of an exchange reaction between CO and CO2 catalyzed by carbon monoxide dehydrogenase.
Biochemistry 2008;47(26):6770-81.
2008: Ragsdale Stephen W
Enzymology of the wood-Ljungdahl pathway of acetogenesis.
Annals of the New York Academy of Sciences 2008;1125():129-36.
2008: Doukov Tzanko I; Blasiak Leah C; Seravalli Javier; Ragsdale Stephen W; Drennan Catherine L
Xenon in and at the end of the tunnel of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
Biochemistry 2008;47(11):3474-83.
2008: Seravalli Javier; Ragsdale Stephen W
Pulse-chase studies of the synthesis of acetyl-CoA by carbon monoxide dehydrogenase/acetyl-CoA synthase: evidence for a random mechanism of methyl and carbonyl addition.
The Journal of biological chemistry 2008;283(13):8384-94.
2008: Kunz Ryan C; Dey Mishtu; Ragsdale Stephen W
Characterization of the thioether product formed from the thiolytic cleavage of the alkyl-nickel bond in methyl-coenzyme M reductase.
Biochemistry 2008;47(8):2661-7.
2008: Ragsdale Stephen W
Catalysis of methyl group transfers involving tetrahydrofolate and B(12).
Vitamins and hormones 2008;79():293-324.
2007: Bianchetti Christopher M; Yi Li; Ragsdale Stephen W; Phillips George N
Comparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2.
The Journal of biological chemistry 2007;282(52):37624-31.
2007: Ragsdale Stephen W
Nickel and the carbon cycle.
Journal of inorganic biochemistry 2007;101(11-12):1657-66.
2007: Dey Mishtu; Kunz Ryan C; Lyons Derek M; Ragsdale Stephen W
Characterization of alkyl-nickel adducts generated by reaction of methyl-coenzyme m reductase with brominated acids.
Biochemistry 2007;46(42):11969-78.
2007: Dey Mishtu; Telser Joshua; Kunz Ryan C; Lees Nicholas S; Ragsdale Stephen W; Hoffman Brian M
Biochemical and spectroscopic studies of the electronic structure and reactivity of a methyl-Ni species formed on methyl-coenzyme M reductase.
Journal of the American Chemical Society 2007;129(36):11030-2.
2007: Parkin Alison; Seravalli Javier; Vincent Kylie A; Ragsdale Stephen W; Armstrong Fraser A
Rapid and efficient electrocatalytic CO2/CO interconversions by Carboxydothermus hydrogenoformans CO dehydrogenase I on an electrode.
Journal of the American Chemical Society 2007;129(34):10328-9.
2007: Yi Li; Ragsdale Stephen W
Evidence that the heme regulatory motifs in heme oxygenase-2 serve as a thiol/disulfide redox switch regulating heme binding.
The Journal of biological chemistry 2007;282(29):21056-67.
2007: Doukov Tzanko I; Hemmi Hisashi; Drennan Catherine L; Ragsdale Stephen W
Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases.
The Journal of biological chemistry 2007;282(9):6609-18.
2006: Kunz Ryan C; Horng Yih-Chern; Ragsdale Stephen W
Spectroscopic and kinetic studies of the reaction of bromopropanesulfonate with methyl-coenzyme M reductase.
The Journal of biological chemistry 2006;281(45):34663-76.
2006: Dey Mishtu; Kunz Ryan C; Van Heuvelen Katherine M; Craft Jennifer L; Horng Yih-Chern; Tang Qun; Bocian David F; George Simon J; Brunold Thomas C; Ragsdale Stephen W
Spectroscopic and computational studies of reduction of the metal versus the tetrapyrrole ring of coenzyme F430 from methyl-coenzyme M reductase.
Biochemistry 2006;45(39):11915-33.
2006: Pop Stelian M; Gupta Nirupama; Raza Ashraf S; Ragsdale Stephen W
Transcriptional activation of dehalorespiration. Identification of redox-active cysteines regulating dimerization and DNA binding.
The Journal of biological chemistry 2006;281(36):26382-90.
2006: Joyce M Gordon; Levy Colin; Gábor Krisztina; Pop Stelian M; Biehl Benjamin D; Doukov Tzanko I; Ryter Jodi M; Mazon Hortense; Smidt Hauke; van den Heuvel Robert H H; Ragsdale Stephen W; van der Oost John; Leys David
CprK crystal structures reveal mechanism for transcriptional control of halorespiration.
The Journal of biological chemistry 2006;281(38):28318-25.
2006: Ragsdale Stephen W
Metals and their scaffolds to promote difficult enzymatic reactions.
Chemical reviews 2006;106(8):3317-37.
2006: Mansoorabadi Steven O; Seravalli Javier; Furdui Cristina; Krymov Vladimir; Gerfen Gary J; Begley Tadhg P; Melnick Jonathan; Ragsdale Stephen W; Reed George H
EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase.
Biochemistry 2006;45(23):7122-31.
2006: Stich Troy A; Seravalli Javier; Venkateshrao Swarnalatha; Spiro Thomas G; Ragsdale Stephen W; Brunold Thomas C
Spectroscopic studies of the corrinoid/iron-sulfur protein from Moorella thermoacetica.
Journal of the American Chemical Society 2006;128(15):5010-20.
2006: Astashkin Andrei V; Seravalli Javier; Mansoorabadi Steven O; Reed George H; Ragsdale Stephen W
Pulsed electron paramagnetic resonance experiments identify the paramagnetic intermediates in the pyruvate ferredoxin oxidoreductase catalytic cycle.
Journal of the American Chemical Society 2006;128(12):3888-9.
2006: Frantom Patrick A; Seravalli Javier; Ragsdale Stephen W; Fitzpatrick Paul F
Reduction and oxidation of the active site iron in tyrosine hydroxylase: kinetics and specificity.
Biochemistry 2006;45(7):2372-9.
2005: George Simon J; Seravalli Javier; Ragsdale Stephen W
EPR and infrared spectroscopic evidence that a kinetically competent paramagnetic intermediate is formed when acetyl-coenzyme A synthase reacts with CO.
Journal of the American Chemical Society 2005;127(39):13500-1.
2004: Pop Stelian M; Kolarik Ryan J; Ragsdale Stephen W
Regulation of anaerobic dehalorespiration by the transcriptional activator CprK.
The Journal of biological chemistry 2004;279(48):49910-8.
2004: Dumitru Razvan V; Ragsdale Stephen W
Mechanism of 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase, a key enzyme in the methanopterin biosynthetic pathway.
The Journal of biological chemistry 2004;279(38):39389-95.
2004: Gu Weiwei; Seravalli Javier; Ragsdale Stephen W; Cramer Stephen P
CO-induced structural rearrangement of the C cluster in Carboxydothermus hydrogenoformans CO dehydrogenase-evidence from Ni K-edge X-ray absorption spectroscopy.
Biochemistry 2004;43(28):9029-35.
2004: Drennan Catherine L; Doukov Tzanko I; Ragsdale Stephen W
The metalloclusters of carbon monoxide dehydrogenase/acetyl-CoA synthase: a story in pictures.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(5):511-5.
2004: Ragsdale Stephen W
Life with carbon monoxide.
Critical reviews in biochemistry and molecular biology 2004;39(3):165-95.
2004: Craft Jennifer L; Horng Yih-Chern; Ragsdale Stephen W; Brunold Thomas C
Nickel oxidation states of F(430) cofactor in methyl-coenzyme M reductase.
Journal of the American Chemical Society 2004;126(13):4068-9.
2004: Seravalli Javier; Xiao Yuming; Gu Weiwei; Cramer Stephen P; Antholine William E; Krymov Vladimir; Gerfen Gary J; Ragsdale Stephen W
Evidence that NiNi acetyl-CoA synthase is active and that the CuNi enzyme is not.
Biochemistry 2004;43(13):3944-55.
2004: Craft Jennifer L; Horng Yih-Chern; Ragsdale Stephen W; Brunold Thomas C
Spectroscopic and computational characterization of the nickel-containing F430 cofactor of methyl-coenzyme M reductase.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(1):77-89.
2003: Chen Jingyi; Huang Shan; Seravalli Javier; Gutzman Howard; Swartz Derrick J; Ragsdale Stephen W; Bagley Kimberly A
Infrared studies of carbon monoxide binding to carbon monoxide dehydrogenase/acetyl-CoA synthase from Moorella thermoacetica.
Biochemistry 2003;42(50):14822-30.
2003: Dumitru Razvan; Palencia Hector; Schroeder Scott D; DeMontigny Bree A; Takacs James M; Rasche Madeline E; Miner Jess L; Ragsdale Stephen W
Targeting methanopterin biosynthesis to inhibit methanogenesis.
Applied and environmental microbiology 2003;69(12):7236-41.
2003: Ragsdale Stephen W
Pyruvate ferredoxin oxidoreductase and its radical intermediate.
Chemical reviews 2003;103(6):2333-46.
2003: Seravalli Javier; Gu Weiwei; Tam Annie; Strauss Erick; Begley Tadhg P; Cramer Stephen P; Ragsdale Stephen W
Functional copper at the acetyl-CoA synthase active site.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3689-94.
2003: Singh Kuljeet; Horng Yih-Chern; Ragsdale Stephen W
Rapid ligand exchange in the MCRred1 form of methyl-coenzyme M reductase.
Journal of the American Chemical Society 2003;125(9):2436-43.
2003: Banerjee Ruma; Ragsdale Stephen W
The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes.
Annual review of biochemistry 2003;72():209-47.
2002: Tang Qun; Carrington Paul E; Horng Yih-Chern; Maroney Michael J; Ragsdale Stephen W; Bocian David F
X-ray absorption and resonance Raman studies of methyl-coenzyme M reductase indicating that ligand exchange and macrocycle reduction accompany reductive activation.
Journal of the American Chemical Society 2002;124(44):13242-56.
2002: Doukov Tzanko I; Iverson Tina M; Seravalli Javier; Ragsdale Stephen W; Drennan Catherine L
A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
Science (New York, N.Y.) 2002;298(5593):567-72.
2002: Furdui Cristina; Ragsdale Stephen W
The roles of coenzyme A in the pyruvate:ferredoxin oxidoreductase reaction mechanism: rate enhancement of electron transfer from a radical intermediate to an iron-sulfur cluster.
Biochemistry 2002;41(31):9921-37.
2002: Seravalli Javier; Kumar Manoj; Ragsdale Stephen W
Rapid kinetic studies of acetyl-CoA synthesis: evidence supporting the catalytic intermediacy of a paramagnetic NiFeC species in the autotrophic Wood-Ljungdahl pathway.
Biochemistry 2002;41(6):1807-19.
2001: Boll M; Fuchs G; Meier C; Trautwein A; El Kasmi A; Ragsdale S W; Buchanan G; Lowe D J
Redox centers of 4-hydroxybenzoyl-CoA reductase, a member of the xanthine oxidase family of molybdenum-containing enzymes.
The Journal of biological chemistry 2001;276(51):47853-62.
2001: Krasotkina J; Walters T; Maruya K A; Ragsdale S W
Characterization of the B12- and iron-sulfur-containing reductive dehalogenase from Desulfitobacterium chlororespirans.
The Journal of biological chemistry 2001;276(44):40991-7.
2001: Horng Y C; Becker D F; Ragsdale S W
Mechanistic studies of methane biogenesis by methyl-coenzyme M reductase: evidence that coenzyme B participates in cleaving the C-S bond of methyl-coenzyme M.
Biochemistry 2001;40(43):12875-85.
2001: Telser J; Davydov R; Horng Y C; Ragsdale S W; Hoffman B M
Cryoreduction of methyl-coenzyme M reductase: EPR characterization of forms, MCR(ox1) and MCR (red1).
Journal of the American Chemical Society 2001;123(25):5853-60.
2001: Naidu D; Ragsdale S W
Characterization of a three-component vanillate O-demethylase from Moorella thermoacetica.
Journal of bacteriology 2001;183(11):3276-81.
2001: Seravalli J; Brown K L; Ragsdale S W
Acetyl coenzyme A synthesis from unnatural methylated corrinoids: requirement for "base-off" coordination at cobalt.
Journal of the American Chemical Society 2001;123(8):1786-7.
2001: Murakami E; Deppenmeier U; Ragsdale S W
Characterization of the intramolecular electron transfer pathway from 2-hydroxyphenazine to the heterodisulfide reductase from Methanosarcina thermophila.
The Journal of biological chemistry 2001;276(4):2432-9.
2000: Furdui C; Ragsdale S W
The role of pyruvate ferredoxin oxidoreductase in pyruvate synthesis during autotrophic growth by the Wood-Ljungdahl pathway.
The Journal of biological chemistry 2000;275(37):28494-9.
2000: Doukov T; Seravalli J; Stezowski J J; Ragsdale S W
Crystal structure of a methyltetrahydrofolate- and corrinoid-dependent methyltransferase.
Structure (London, England : 1993) 2000;8(8):817-30.
2000: Seravalli J; Ragsdale S W
Channeling of carbon monoxide during anaerobic carbon dioxide fixation.
Biochemistry 2000;39(6):1274-7.
2000: Murakami E; Ragsdale S W
Evidence for intersubunit communication during acetyl-CoA cleavage by the multienzyme CO dehydrogenase/acetyl-CoA synthase complex from Methanosarcina thermophila. Evidence that the beta subunit catalyzes C-C and C-S bond cleavage.
The Journal of biological chemistry 2000;275(7):4699-707.
2000: Ragsdale S W
Nickel containing CO dehydrogenases and hydrogenases.
Sub-cellular biochemistry 2000;35():487-518.
1999: Seravalli J; Shoemaker R K; Sudbeck M J; Ragsdale S W
Binding of (6R,S)-methyltetrahydrofolate to methyltransferase from Clostridium thermoaceticum: role of protonation of methyltetrahydrofolate in the mechanism of methyl transfer.
Biochemistry 1999;38(18):5736-45.
1999: Seravalli J; Zhao S; Ragsdale S W
Mechanism of transfer of the methyl group from (6S)-methyltetrahydrofolate to the corrinoid/iron-sulfur protein catalyzed by the methyltransferase from Clostridium thermoaceticum: a key step in the Wood-Ljungdahl pathway of acetyl-CoA synthesis.
Biochemistry 1999;38(18):5728-35.
1999: Menon S; Ragsdale S W
The role of an iron-sulfur cluster in an enzymatic methylation reaction. Methylation of CO dehydrogenase/acetyl-CoA synthase by the methylated corrinoid iron-sulfur protein.
The Journal of biological chemistry 1999;274(17):11513-8.
1999: Arendsen A F; Soliman M Q; Ragsdale S W
Nitrate-dependent regulation of acetate biosynthesis and nitrate respiration by Clostridium thermoaceticum.
Journal of bacteriology 1999;181(5):1489-95.
1998: Ogrünç M; Becker D F; Ragsdale S W; Sancar A
Nucleotide excision repair in the third kingdom.
Journal of bacteriology 1998;180(21):5796-8.
1998: Becker D F; Leartsakulpanich U; Surerus K K; Ferry J G; Ragsdale S W
Electrochemical and spectroscopic properties of the iron-sulfur flavoprotein from Methanosarcina thermophila.
The Journal of biological chemistry 1998;273(41):26462-9.
1998: Simianu M; Murakami E; Brewer J M; Ragsdale S W
Purification and properties of the heme- and iron-sulfur-containing heterodisulfide reductase from Methanosarcina thermophila.
Biochemistry 1998;37(28):10027-39.
1998: Bäumer S; Murakami E; Brodersen J; Gottschalk G; Ragsdale S W; Deppenmeier U
The F420H2:heterodisulfide oxidoreductase system from Methanosarcina species. 2-Hydroxyphenazine mediates electron transfer from F420H2 dehydrogenase to heterodisulfide reductase.
FEBS letters 1998;428(3):295-8.
1998: Ragsdale S W
Nickel biochemistry.
Current opinion in chemical biology 1998;2(2):208-15.
1998: Menon S; Ragsdale S W
Role of the [4Fe-4S] cluster in reductive activation of the cobalt center of the corrinoid iron-sulfur protein from Clostridium thermoaceticum during acetate biosynthesis.
Biochemistry 1998;37(16):5689-98.
1998: Becker D F; Ragsdale S W
Activation of methyl-SCoM reductase to high specific activity after treatment of whole cells with sodium sulfide.
Biochemistry 1998;37(8):2639-47.
1997: Seravalli J; Kumar M; Lu W P; Ragsdale S W
Mechanism of carbon monoxide oxidation by the carbon monoxide dehydrogenase/acetyl-CoA synthase from Clostridium thermoaceticum: kinetic characterization of the intermediates.
Biochemistry 1997;36(37):11241-51.
1997: Menon S; Ragsdale S W
Mechanism of the Clostridium thermoaceticum pyruvate:ferredoxin oxidoreductase: evidence for the common catalytic intermediacy of the hydroxyethylthiamine pyropyrosphate radical.
Biochemistry 1997;36(28):8484-94.
1997: Ragsdale S W
The eastern and western branches of the Wood/Ljungdahl pathway: how the east and west were won.
BioFactors (Oxford, England) 1997;6(1):3-11.
1996: Menon S; Ragsdale S W
Unleashing hydrogenase activity in carbon monoxide dehydrogenase/acetyl-CoA synthase and pyruvate:ferredoxin oxidoreductase.
Biochemistry 1996;35(49):15814-21.
1996: Menon S; Ragsdale S W
Evidence that carbon monoxide is an obligatory intermediate in anaerobic acetyl-CoA synthesis.
Biochemistry 1996;35(37):12119-25.
1996: Zhao S; Ragsdale S W
A conformational change in the methyltransferase from Clostridium thermoaceticum facilitates the methyl transfer from (6S)-methyltetrahydrofolate to the corrinoid/iron-sulfur protein in the Acetyl-CoA pathway.
Biochemistry 1996;35(7):2476-81.
1995: Doukov T I; Zhao S; Ross C R; Roberts D L; Kim J J; Ragsdale S W; Stezowski J J
Preliminary X-ray crystallographic study of methyltetrahydrofolate: corrinoid/iron sulfur protein methyltransferase from Clostridium thermoaceticum.
Acta crystallographica. Section D, Biological crystallography 1995;51(Pt 6):1092-3.
1995: Zhao S; Roberts D L; Ragsdale S W
Mechanistic studies of the methyltransferase from Clostridium thermoaceticum: origin of the pH dependence of the methyl group transfer from methyltetrahydrofolate to the corrinoid/iron-sulfur protein.
Biochemistry 1995;34(46):15075-83.
1995: Kumar M; Qiu D; Spiro T G; Ragsdale S W
A methylnickel intermediate in a bimetallic mechanism of acetyl-coenzyme A synthesis by anaerobic bacteria.
Science (New York, N.Y.) 1995;270(5236):628-30.
1995: el Kasmi A; Brachmann R; Fuchs G; Ragsdale S W
Hydroxybenzoyl-CoA reductase: coupling kinetics and electrochemistry to derive enzyme mechanisms.
Biochemistry 1995;34(37):11668-77.
1995: Seravalli J; Kumar M; Lu W P; Ragsdale S W
Mechanism of CO oxidation by carbon monoxide dehydrogenase from Clostridium thermoaceticum and its inhibition by anions.
Biochemistry 1995;34(24):7879-88.
1995: Lu W P; Becher B; Gottschalk G; Ragsdale S W
Electron paramagnetic resonance spectroscopic and electrochemical characterization of the partially purified N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanosarcina mazei Gö1.
Journal of bacteriology 1995;177(9):2245-50.
1995: Wirt M D; Kumar M; Wu J J; Scheuring E M; Ragsdale S W; Chance M R
Structural and electronic factors in heterolytic cleavage: formation of the Co(I) intermediate in the corrinoid/iron-sulfur protein from Clostridium thermoaceticum.
Biochemistry 1995;34(15):5269-73.
1994: Roberts D L; Zhao S; Doukov T; Ragsdale S W
The reductive acetyl coenzyme A pathway: sequence and heterologous expression of active methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase from Clostridium thermoaceticum.
Journal of bacteriology 1994;176(19):6127-30.
1994: el Kasmi A; Rajasekharan S; Ragsdale S W
Anaerobic pathway for conversion of the methyl group of aromatic methyl ethers to acetic acid by Clostridium thermoaceticum.
Biochemistry 1994;33(37):11217-24.
1994: Kumar M; Lu W P; Ragsdale S W
Binding of carbon disulfide to the site of acetyl-CoA synthesis by the nickel-iron-sulfur protein, carbon monoxide dehydrogenase, from Clostridium thermoaceticum.
Biochemistry 1994;33(32):9769-77.
1994: Qiu D; Kumar M; Ragsdale S W; Spiro T G
Nature's carbonylation catalyst: Raman spectroscopic evidence that carbon monoxide binds to iron, not nickel, in CO dehydrogenase.
Science (New York, N.Y.) 1994;264(5160):817-9.
1994: Clements A P; Kilpatrick L; Lu W P; Ragsdale S W; Ferry J G
Characterization of the iron-sulfur clusters in ferredoxin from acetate-grown Methanosarcina thermophila.
Journal of bacteriology 1994;176(9):2689-93.
1994: Lu W P; Jablonski P E; Rasche M; Ferry J G; Ragsdale S W
Characterization of the metal centers of the Ni/Fe-S component of the carbon-monoxide dehydrogenase enzyme complex from Methanosarcina thermophila.
The Journal of biological chemistry 1994;269(13):9736-42.
1993: Lu W P; Schiau I; Cunningham J R; Ragsdale S W
Sequence and expression of the gene encoding the corrinoid/iron-sulfur protein from Clostridium thermoaceticum and reconstitution of the recombinant protein to full activity.
The Journal of biological chemistry 1993;268(8):5605-14.
1993: Jablonski P E; Lu W P; Ragsdale S W; Ferry J G
Characterization of the metal centers of the corrinoid/iron-sulfur component of the CO dehydrogenase enzyme complex from Methanosarcina thermophila by EPR spectroscopy and spectroelectrochemistry.
The Journal of biological chemistry 1993;268(1):325-9.
1992: Roberts J R; Lu W P; Ragsdale S W
Acetyl-coenzyme A synthesis from methyltetrahydrofolate, CO, and coenzyme A by enzymes purified from Clostridium thermoaceticum: attainment of in vivo rates and identification of rate-limiting steps.
Journal of bacteriology 1992;174(14):4667-76.
1991: Morton T A; Runquist J A; Ragsdale S W; Shanmugasundaram T; Wood H G; Ljungdahl L G
The primary structure of the subunits of carbon monoxide dehydrogenase/acetyl-CoA synthase from Clostridium thermoaceticum.
The Journal of biological chemistry 1991;266(35):23824-8.
1991: Gorst C M; Ragsdale S W
Characterization of the NiFeCO complex of carbon monoxide dehydrogenase as a catalytically competent intermediate in the pathway of acetyl-coenzyme A synthesis.
The Journal of biological chemistry 1991;266(31):20687-93.
1991: Lu W P; Ragsdale S W
Reductive activation of the coenzyme A/acetyl-CoA isotopic exchange reaction catalyzed by carbon monoxide dehydrogenase from Clostridium thermoaceticum and its inhibition by nitrous oxide and carbon monoxide.
The Journal of biological chemistry 1991;266(6):3554-64.
1991: Fan C L; Gorst C M; Ragsdale S W; Hoffman B M
Characterization of the Ni-Fe-C complex formed by reaction of carbon monoxide with the carbon monoxide dehydrogenase from Clostridium thermoaceticum by Q-band ENDOR.
Biochemistry 1991;30(2):431-5.
1991: Ragsdale S W
Enzymology of the acetyl-CoA pathway of CO2 fixation.
Critical reviews in biochemistry and molecular biology 1991;26(3-4):261-300.
1990: Baur J R; Graves M C; Feinberg B A; Ragsdale S W
Characterization of the recombinant Clostridium pasteurianum ferredoxin and comparison of its properties with those of the native protein.
BioFactors (Oxford, England) 1990;2(3):197-203.
1990: Matthews R G; Banerjee R V; Ragsdale S W
Cobamide-dependent methyl transferases.
BioFactors (Oxford, England) 1990;2(3):147-52.
1990: Lindahl P A; Ragsdale S W; Münck E
Mössbauer study of CO dehydrogenase from Clostridium thermoaceticum.
The Journal of biological chemistry 1990;265(7):3880-8.
1990: Lindahl P A; Münck E; Ragsdale S W
CO dehydrogenase from Clostridium thermoaceticum. EPR and electrochemical studies in CO2 and argon atmospheres.
The Journal of biological chemistry 1990;265(7):3873-9.
1990: Lu W P; Harder S R; Ragsdale S W
Controlled potential enzymology of methyl transfer reactions involved in acetyl-CoA synthesis by CO dehydrogenase and the corrinoid/iron-sulfur protein from Clostridium thermoaceticum.
The Journal of biological chemistry 1990;265(6):3124-33.
1990: Banerjee R V; Harder S R; Ragsdale S W; Matthews R G
Mechanism of reductive activation of cobalamin-dependent methionine synthase: an electron paramagnetic resonance spectroelectrochemical study.
Biochemistry 1990;29(5):1129-35.
1989: Harder S R; Lu W P; Feinberg B A; Ragsdale S W
Spectroelectrochemical studies of the corrinoid/iron-sulfur protein involved in acetyl coenzyme A synthesis by Clostridium thermoaceticum.
Biochemistry 1989;28(23):9080-7.
1989: Harder S R; Feinberg B A; Ragsdale S W
A spectroelectrochemical cell designed for low temperature electron paramagnetic resonance titration of oxygen-sensitive proteins.
Analytical biochemistry 1989;181(2):283-7.
1989: Roberts D L; James-Hagstrom J E; Garvin D K; Gorst C M; Runquist J A; Baur J R; Haase F C; Ragsdale S W
Cloning and expression of the gene cluster encoding key proteins involved in acetyl-CoA synthesis in Clostridium thermoaceticum: CO dehydrogenase, the corrinoid/Fe-S protein, and methyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(1):32-6.
1988: Shanmugasundaram T; Ragsdale S W; Wood H G
Role of carbon monoxide dehydrogenase in acetate synthesis by the acetogenic bacterium, Acetobacterium woodii.
BioFactors (Oxford, England) 1988;1(2):147-52.
1987: Ragsdale S W; Lindahl P A; Münck E
Mössbauer, EPR, and optical studies of the corrinoid/iron-sulfur protein involved in the synthesis of acetyl coenzyme A by Clostridium thermoaceticum.
The Journal of biological chemistry 1987;262(29):14289-97.
1986: Wood H G; Ragsdale S W; Pezacka E
A new pathway of autotrophic growth utilizing carbon monoxide or carbon dioxide and hydrogen.
Biochemistry international 1986;12(3):421-40.
1985: Ragsdale S W; Wood H G; Antholine W E
Evidence that an iron-nickel-carbon complex is formed by reaction of CO with the CO dehydrogenase from Clostridium thermoaceticum.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(20):6811-4.
1985: Ragsdale S W; Wood H G
Acetate biosynthesis by acetogenic bacteria. Evidence that carbon monoxide dehydrogenase is the condensing enzyme that catalyzes the final steps of the synthesis.
The Journal of biological chemistry 1985;260(7):3970-7.
1984: Ragsdale S W; Ljungdahl L G
Hydrogenase from Acetobacterium woodii.
Archives of microbiology 1984;139(4):361-5.
1984: Ragsdale S W; Ljungdahl L G
Purification and properties of NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Acetobacterium woodii.
The Journal of biological chemistry 1984;259(6):3499-503.
1984: Ragsdale S W; Ljungdahl L G
Characterization of ferredoxin, flavodoxin, and rubredoxin from Clostridium formicoaceticum grown in media with high and low iron contents.
Journal of bacteriology 1984;157(1):1-6.
1983: Ragsdale S W; Ljungdahl L G; DerVartanian D V
13C and 61Ni isotope substitutions confirm the presence of a nickel (III)-carbon species in acetogenic CO dehydrogenases.
Biochemical and biophysical research communications 1983;115(2):658-65.
1983: Ragsdale S W; Ljungdahl L G; DerVartanian D V
Isolation of carbon monoxide dehydrogenase from Acetobacterium woodii and comparison of its properties with those of the Clostridium thermoaceticum enzyme.
Journal of bacteriology 1983;155(3):1224-37.
1983: Ragsdale S W; Clark J E; Ljungdahl L G; Lundie L L; Drake H L
Properties of purified carbon monoxide dehydrogenase from Clostridium thermoaceticum, a nickel, iron-sulfur protein.
The Journal of biological chemistry 1983;258(4):2364-9.
1982: Ragsdale S W; Ljungdahl L G; DerVartanian D V
EPR evidence for nickel-substrate interaction in carbon monoxide dehydrogenase from Clostridium thermoaceticum.
Biochemical and biophysical research communications 1982;108(2):658-63.
1982: Clark J E; Ragsdale S W; Ljungdahl L G; Wiegel J
Levels of enzymes involved in the synthesis of acetate from CO2 in Clostridium thermoautotrophicum.
Journal of bacteriology 1982;151(1):507-9.

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