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Irfan Rahman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Chemicals & Drugs

Activities & Behaviors

Smoking

Anatomy

Phenomena

Oxidation-Reduction

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Network (preview)

Co-Publications
Name
41
MacNee, William
21
Donaldson, Ken
15
Yang, Se-Ran
12
Biswas, Saibal
10
Gilmour, Peter
10
Kode, Aruna
9
Antonicelli, Frank
8
Kirkham, Paul
6
Marwick, John
5
Phipps, Richard
5
Drost, Ellen
5
Jimenez, Luis
4
Harrison, David
4
Hiemstra, Pieter
4
Hirani, Nik

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Publications

TOP 3
Rajendrasozhan Saravanan; Yao Hongwei; Rahman Irfan
Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD.
Yao Hongwei; Rahman Irfan
Current concepts on the role of inflammation in COPD and lung cancer.
Adenuga David; Yao Hongwei; March Thomas H; Seagrave Jeanclare; Rahman Irfan
Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke.

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All Publications

2009: Rajendrasozhan Saravanan; Yao Hongwei; Rahman Irfan
Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD.
COPD 2009;6(4):291-7.
2009: Yao Hongwei; Rahman Irfan
Current concepts on the role of inflammation in COPD and lung cancer.
Current opinion in pharmacology 2009;9(4):375-83.
2009: Adenuga David; Yao Hongwei; March Thomas H; Seagrave Jeanclare; Rahman Irfan
Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke.
American journal of respiratory cell and molecular biology 2009;40(4):464-73.
2009: Biswas Saibal K; Rahman Irfan
Environmental toxicity, redox signaling and lung inflammation: the role of glutathione.
Molecular aspects of medicine 2009;30(1-2):60-76.
2009: Yang Se-Ran; Yao Hongwei; Rajendrasozhan Saravanan; Chung Sangwoon; Edirisinghe Indika; Valvo Samantha; Fromm George; McCabe Michael J; Sime Patricia J; Phipps Richard P; Li Jian-Dong; Bulger Michael; Rahman Irfan
RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke.
American journal of respiratory cell and molecular biology 2009;40(2):147-58.
2008: Rahman Irfan
Antioxidant therapeutic advances in COPD.
Therapeutic advances in respiratory disease 2008;2(6):351-74.
2008: Meja Koremu K; Rajendrasozhan Saravanan; Adenuga David; Biswas Saibal K; Sundar Isaac K; Spooner Gillian; Marwick John A; Chakravarty Probir; Fletcher Danielle; Whittaker Paul; Megson Ian L; Kirkham Paul A; Rahman Irfan
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2.
American journal of respiratory cell and molecular biology 2008;39(3):312-23.
2008: Biswas Saibal; Rahman Irfan
Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin.
Molecular nutrition & food research 2008;52(9):987-94.
2008: Edirisinghe Indika; Yang Se-Ran; Yao Hongwei; Rajendrasozhan Saravanan; Caito Samuel; Adenuga David; Wong Chelsea; Rahman Arshad; Phipps Richard P; Jin Zheng-Gen; Rahman Irfan
VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(7):2297-310.
2008: Yao Hongwei; Yang Se-Ran; Edirisinghe Indika; Rajendrasozhan Saravanan; Caito Samuel; Adenuga David; O'Reilly Michael A; Rahman Irfan
Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice.
American journal of respiratory cell and molecular biology 2008;39(1):7-18.
2008: Yao Hongwei; Edirisinghe Indika; Rajendrasozhan Saravanan; Yang Se-Ran; Caito Samuel; Adenuga David; Rahman Irfan
Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice.
American journal of physiology. Lung cellular and molecular physiology 2008;294(6):L1174-86.
2008: Yang Se-Ran; Valvo Samantha; Yao Hongwei; Kode Aruna; Rajendrasozhan Saravanan; Edirisinghe Indika; Caito Samuel; Adenuga David; Henry Ryan; Fromm George; Maggirwar Sanjay; Li Jian-Dong; Bulger Michael; Rahman Irfan
IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung.
American journal of respiratory cell and molecular biology 2008;38(6):689-98.
2008: Yao Hongwei; Edirisinghe Indika; Yang Se-Ran; Rajendrasozhan Saravanan; Kode Aruna; Caito Samuel; Adenuga David; Rahman Irfan
Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice.
The American journal of pathology 2008;172(5):1222-37.
2008: Rajendrasozhan Saravanan; Yang Se-Ran; Edirisinghe Indika; Yao Hongwei; Adenuga David; Rahman Irfan
Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD.
Antioxidants & redox signaling 2008;10(4):799-811.
2008: Rajendrasozhan Saravanan; Yang Se-Ran; Kinnula Vuokko L; Rahman Irfan
SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2008;177(8):861-70.
2008: Kode Aruna; Rajendrasozhan Saravanan; Caito Samuel; Yang Se-Ran; Megson Ian L; Rahman Irfan
Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2008;294(3):L478-88.
2008: Ryan Elizabeth P; Bushnell Timothy P; Friedman Alan E; Rahman Irfan; Phipps Richard P
Cyclooxygenase-2 independent effects of cyclooxygenase-2 inhibitors on oxidative stress and intracellular glutathione content in normal and malignant human B-cells.
Cancer immunology, immunotherapy : CII 2008;57(3):347-58.
2008: Caito Samuel; Yang Se-Ran; Kode Aruna; Edirisinghe Indika; Rajendrasozhan Saravanan; Phipps Richard P; Rahman Irfan
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages.
Antioxidants & redox signaling 2008;10(2):253-60.
2007: Yao H; Yang S-R; Kode A; Rajendrasozhan S; Caito S; Adenuga D; Henry R; Edirisinghe I; Rahman I
Redox regulation of lung inflammation: role of NADPH oxidase and NF-kappaB signalling.
Biochemical Society transactions 2007;35(Pt 5):1151-5.
2007: Stevenson Christopher S; Docx Cerys; Webster Ruth; Battram Cliff; Hynx Debra; Giddings June; Cooper Philip R; Chakravarty Probir; Rahman Irfan; Marwick John A; Kirkham Paul A; Charman Christine; Richardson Delwood L; Nirmala N R; Whittaker Paul; Butler Keith
Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.
American journal of physiology. Lung cellular and molecular physiology 2007;293(5):L1183-93.
2007: Yang Se-Ran; Wright Jessica; Bauter Mark; Seweryniak Kathryn; Kode Aruna; Rahman Irfan
Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.
American journal of physiology. Lung cellular and molecular physiology 2007;292(2):L567-76.
2006: Morrison Douglas; Rahman Irfan; MacNee William
Permeability, inflammation and oxidant status in airspace epithelium exposed to ozone.
Respiratory medicine 2006;100(12):2227-34.
2006: Rahman Irfan; Biswas Saibal K; Kirkham Paul A
Regulation of inflammation and redox signaling by dietary polyphenols.
Biochemical pharmacology 2006;72(11):1439-52.
2006: Rahman I; Adcock I M
Oxidative stress and redox regulation of lung inflammation in COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;28(1):219-42.
2006: Yang Se-Ran; Chida Asiya S; Bauter Mark R; Shafiq Nusrat; Seweryniak Kathryn; Maggirwar Sanjay B; Kilty Iain; Rahman Irfan
Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages.
American journal of physiology. Lung cellular and molecular physiology 2006;291(1):L46-57.
2006: Baglole Carolyn J; Bushinsky Seth M; Garcia Tatiana M; Kode Aruna; Rahman Irfan; Sime Patricia J; Phipps Richard P
Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema.
American journal of physiology. Lung cellular and molecular physiology 2006;291(1):L19-29.
2006: Rahman Irfan; Kilty Iain
Antioxidant therapeutic targets in COPD.
Current drug targets 2006;7(6):707-20.
2006: Marwick John A; Stevenson Christopher S; Giddings June; MacNee William; Butler Keith; Rahman Irfan; Kirkham Paul A
Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition.
American journal of physiology. Lung cellular and molecular physiology 2006;290(5):L897-908.
2006: Rahman Irfan; Yang Se-Ran; Biswas Saibal K
Current concepts of redox signaling in the lungs.
Antioxidants & redox signaling 2006;8(3-4):681-9.
2006: Rahman Irfan; Biswas Saibal K; Kode Aruna
Oxidant and antioxidant balance in the airways and airway diseases.
European journal of pharmacology 2006;533(1-3):222-39.
2006: Rahman Irfan
Antioxidant therapies in COPD.
International journal of chronic obstructive pulmonary disease 2006;1(1):15-29.
2006: Rahman Irfan; Kode Aruna; Biswas Saibal K
Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method.
Nature protocols 2006;1(6):3159-65.
2006: Kode Aruna; Yang Se-Ran; Rahman Irfan
Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells.
Respiratory research 2006;7():132.
2005: Biswas Saibal K; Newby David E; Rahman Irfan; Megson Ian L
Depressed glutathione synthesis precedes oxidative stress and atherogenesis in Apo-E(-/-) mice.
Biochemical and biophysical research communications 2005;338(3):1368-73.
2005: Rahman Irfan
Regulation of glutathione in inflammation and chronic lung diseases.
Mutation research 2005;579(1-2):58-80.
2005: Rahman Irfan; Biswas Saibal K; Jimenez Luis A; Torres Martine; Forman H J
Glutathione, stress responses, and redox signaling in lung inflammation.
Antioxidants & redox signaling 2005;7(1-2):42-59.
2005: Biswas Saibal K; McClure Danny; Jimenez Luis A; Megson Ian L; Rahman Irfan
Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity.
Antioxidants & redox signaling 2005;7(1-2):32-41.
2005: Luppi Fabrizio; Aarbiou Jamil; van Wetering Sandra; Rahman Irfan; de Boer Willem I; Rabe Klaus F; Hiemstra Pieter S
Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione.
Respiratory research 2005;6():140.
2005: Rahman Irfan
Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms.
Cell biochemistry and biophysics 2005;43(1):167-88.
2005: Rahman Irfan
The role of oxidative stress in the pathogenesis of COPD: implications for therapy.
Treatments in respiratory medicine 2005;4(3):175-200.
2004: Moodie Fiona M; Marwick John A; Anderson Charlotte S; Szulakowski Patryk; Biswas Saibal K; Bauter Mark R; Kilty Iain; Rahman Irfan
Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(15):1897-9.
2004: Marwick John A; Kirkham Paul A; Stevenson Christopher S; Danahay Henry; Giddings June; Butler Keith; Donaldson Kenneth; Macnee William; Rahman Irfan
Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs.
American journal of respiratory cell and molecular biology 2004;31(6):633-42.
2004: Rahman Irfan; Marwick John; Kirkham Paul
Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression.
Biochemical pharmacology 2004;68(6):1255-67.
2004: Antonicelli Frank; Brown David; Parmentier Maryline; Drost Ellen M; Hirani Nik; Rahman Irfan; Donaldson Ken; MacNee William
Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn.
American journal of physiology. Lung cellular and molecular physiology 2004;286(6):L1319-27.
2004: Kirkham Paul A; Spooner Gillian; Rahman Irfan; Rossi Adriano G
Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products.
Biochemical and biophysical research communications 2004;318(1):32-7.
2004: Rahman Irfan; Biswas Saibal K
Non-invasive biomarkers of oxidative stress: reproducibility and methodological issues.
Redox report : communications in free radical research 2004;9(3):125-43.
2003: Rahman Irfan; Kelly Frank
Biomarkers in breath condensate: a promising new non-invasive technique in free radical research.
Free radical research 2003;37(12):1253-66.
2003: Wickenden Julie A; Clarke Murray C H; Rossi Adriano G; Rahman Irfan; Faux Stephen P; Donaldson Kenneth; MacNee William
Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis.
American journal of respiratory cell and molecular biology 2003;29(5):562-70.
2003: Donaldson Ken; Stone Vicki; Borm Paul J A; Jimenez Luis A; Gilmour Peter S; Schins Roel P F; Knaapen Ad M; Rahman Irfan; Faux Stephen P; Brown David M; MacNee William
Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10).
Free radical biology & medicine 2003;34(11):1369-82.
2003: Rahman Irfan; Tomasi Aldo
2nd International Meeting on Free Radicals in Health and Disease. The role of oxidants and antioxidants in the regulation of chronic diseases, may 8-12, 2002, Istanbul, Turkey.
Free radical research 2003;37(4):349-54.
2003: Rahman Irfan; Gilmour Peter S; Jimenez Luis A; Biswas Saibal K; Antonicelli Frank; Aruoma Okezie I
Ergothioneine inhibits oxidative stress- and TNF-alpha-induced NF-kappa B activation and interleukin-8 release in alveolar epithelial cells.
Biochemical and biophysical research communications 2003;302(4):860-4.
2003: Gilmour Peter S; Rahman Irfan; Donaldson Kenneth; MacNee William
Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles.
American journal of physiology. Lung cellular and molecular physiology 2003;284(3):L533-40.
2003: Rahman Irfan
Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases.
Journal of biochemistry and molecular biology 2003;36(1):95-109.
2002: Marwick John A; Kirkham Paul; Gilmour Peter S; Donaldson Kenneth; MacNEE William; Rahman Irfan
Cigarette smoke-induced oxidative stress and TGF-beta1 increase p21waf1/cip1 expression in alveolar epithelial cells.
Annals of the New York Academy of Sciences 2002;973():278-83.
2002: Rahman Irfan
Oxidative stress and gene transcription in asthma and chronic obstructive pulmonary disease: antioxidant therapeutic targets.
Current drug targets. Inflammation and allergy 2002;1(3):291-315.
2002: Rahman Irfan
Oxidative stress, transcription factors and chromatin remodelling in lung inflammation.
Biochemical pharmacology 2002;64(5-6):935-42.
2002: Deiana Monica; Dessi M Assunta; Ke Bin; Liang Yun-Fei; Higa Teruo; Gilmour Peter S; Jen Ling-Sun; Rahman Irfan; Aruoma Okezie I
The antioxidant cocktail effective microorganism X (EM-X) inhibits oxidant-induced interleukin-8 release and the peroxidation of phospholipids in vitro.
Biochemical and biophysical research communications 2002;296(5):1148-51.
2002: Rahman Irfan; van Schadewijk Annemarie A M; Crowther Ann J L; Hiemstra Pieter S; Stolk Jan; MacNee William; De Boer Willem I
4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2002;166(4):490-5.
2002: Jardine Hazel; MacNee William; Donaldson Kenneth; Rahman Irfan
Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1.
The Journal of biological chemistry 2002;277(24):21158-66.
2002: Rahman Irfan; Gilmour Peter S; Jimenez Luis Albert; MacNee William
Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation.
Molecular and cellular biochemistry 2002;234-235(1-2):239-48.
2002: Antonicelli Frank; Parmentier Maryline; Drost Ellen M; Hirani Nik; Rahman Irfan; Donaldson Ken; MacNee William
Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells.
Free radical biology & medicine 2002;32(6):492-502.
2002: Jiménez L A; Drost E M; Gilmour P S; Rahman I; Antonicelli F; Ritchie H; MacNee W; Donaldson K
PM(10)-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-alpha.
American journal of physiology. Lung cellular and molecular physiology 2002;282(2):L237-48.
2002: Coe Jonathan P; Rahman Irfan; Sphyris Nathalie; Clarke Alan R; Harrison David J
Glutathione and p53 independently mediate responses against oxidative stress in ES cells.
Free radical biology & medicine 2002;32(2):187-96.
2001: Rahman I; Mulier B; Gilmour P S; Watchorn T; Donaldson K; Jeffery P K; MacNee W
Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB.
Biochemical pharmacology 2001;62(6):787-94.
2001: Gilmour P S; Rahman I; Hayashi S; Hogg J C; Donaldson K; MacNee W
Adenoviral E1A primes alveolar epithelial cells to PM(10)-induced transcription of interleukin-8.
American journal of physiology. Lung cellular and molecular physiology 2001;281(3):L598-606.
2000: Parmentier M; Hirani N; Rahman I; Donaldson K; MacNee W; Antonicelli F
Regulation of lipopolysaccharide-mediated interleukin-1beta release by N-acetylcysteine in THP-1 cells.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(5):933-9.
2000: Rahman I
Regulation of nuclear factor-kappa B, activator protein-1, and glutathione levels by tumor necrosis factor-alpha and dexamethasone in alveolar epithelial cells.
Biochemical pharmacology 2000;60(8):1041-9.
2000: Rahman I; MacNee W
Oxidative stress and regulation of glutathione in lung inflammation.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(3):534-54.
2000: Jiménez L A; Thompson J; Brown D A; Rahman I; Antonicelli F; Duffin R; Drost E M; Hay R T; Donaldson K; MacNee W
Activation of NF-kappaB by PM(10) occurs via an iron-mediated mechanism in the absence of IkappaB degradation.
Toxicology and applied pharmacology 2000;166(2):101-10.
2000: Rahman I; MacNee W
Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches.
Free radical biology & medicine 2000;28(9):1405-20.
2000: Rahman I; van Schadewijk A A; Hiemstra P S; Stolk J; van Krieken J H; MacNee W; de Boer W I
Localization of gamma-glutamylcysteine synthetase messenger rna expression in lungs of smokers and patients with chronic obstructive pulmonary disease.
Free radical biology & medicine 2000;28(6):920-5.
2000: Ward C; Wong T H; Murray J; Rahman I; Haslett C; Chilvers E R; Rossi A G
Induction of human neutrophil apoptosis by nitric oxide donors: evidence for a caspase-dependent, cyclic-GMP-independent, mechanism.
Biochemical pharmacology 2000;59(3):305-14.
1999: Rahman I; MacNee W
Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease.
The American journal of physiology 1999;277(6 Pt 1):L1067-88.
1999: Macnee W; Rahman I
Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 1999;160(5 Pt 2):S58-65.
1999: Rahman I; Skwarska E; Henry M; Davis M; O'Connor C M; FitzGerald M X; Greening A; MacNee W
Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis.
Free radical biology & medicine 1999;27(1-2):60-8.
1999: Rahman I; Antonicelli F; MacNee W
Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells.
The Journal of biological chemistry 1999;274(8):5088-96.
1999: Morrison D; Rahman I; Lannan S; MacNee W
Epithelial permeability, inflammation, and oxidant stress in the air spaces of smokers.
American journal of respiratory and critical care medicine 1999;159(2):473-9.
1999: Lapperre T S; Jimenez L A; Antonicelli F; Drost E M; Hiemstra P S; Stolk J; MacNee W; Rahman I
Apocynin increases glutathione synthesis and activates AP-1 in alveolar epithelial cells.
FEBS letters 1999;443(2):235-9.
1999: Rahman I
Inflammation and the regulation of glutathione level in lung epithelial cells.
Antioxidants & redox signaling 1999;1(4):425-47.
1998: Rahman I; MacNee W
Role of transcription factors in inflammatory lung diseases.
Thorax 1998;53(7):601-12.
1998: Rahman I; Bel A; Mulier B; Donaldson K; MacNee W
Differential regulation of glutathione by oxidants and dexamethasone in alveolar epithelial cells.
The American journal of physiology 1998;275(1 Pt 1):L80-6.
1998: Rossi A G; Haslett C; Hirani N; Greening A P; Rahman I; Metz C N; Bucala R; Donnelly S C
Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma.
The Journal of clinical investigation 1998;101(12):2869-74.
1998: Rahman I; Smith C A; Antonicelli F; MacNee W
Characterisation of gamma-glutamylcysteine synthetase-heavy subunit promoter: a critical role for AP-1.
FEBS letters 1998;427(1):129-33.
1998: Mulier B; Rahman I; Watchorn T; Donaldson K; MacNee W; Jeffery P K
Hydrogen peroxide-induced epithelial injury: the protective role of intracellular nonprotein thiols (NPSH).
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(2):384-91.
1997: Gilmour P S; Brown D M; Beswick P H; MacNee W; Rahman I; Donaldson K
Free radical activity of industrial fibers: role of iron in oxidative stress and activation of transcription factors.
Environmental health perspectives 1997;105 Suppl 5():1313-7.
1997: Rahman I; Skwarska E; MacNee W
Attenuation of oxidant/antioxidant imbalance during treatment of exacerbations of chronic obstructive pulmonary disease.
Thorax 1997;52(6):565-8.
1996: Rahman I; Bel A; Mulier B; Lawson M F; Harrison D J; Macnee W; Smith C A
Transcriptional regulation of gamma-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells.
Biochemical and biophysical research communications 1996;229(3):832-7.
1996: Rahman I; Smith C A; Lawson M F; Harrison D J; MacNee W
Induction of gamma-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells.
FEBS letters 1996;396(1):21-5.
1996: Rahman I; Morrison D; Donaldson K; MacNee W
Systemic oxidative stress in asthma, COPD, and smokers.
American journal of respiratory and critical care medicine 1996;154(4 Pt 1):1055-60.
1996: Li X Y; Rahman I; Donaldson K; MacNee W
Mechanisms of cigarette smoke induced increased airspace permeability.
Thorax 1996;51(5):465-71.
1996: MacNee W; Morrison D; Rahman I; Li X Y; Donaldson K
Cigarette smoke and ozone-induced epithelial perturbation in vivo and in vitro. The role of glutathione.
Chest 1996;109(3 Suppl):39S.
1996: Rahman I; MacNee W
Role of oxidants/antioxidants in smoking-induced lung diseases.
Free radical biology & medicine 1996;21(5):669-81.
1995: Rahman I; Li X Y; Donaldson K; Harrison D J; MacNee W
Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress.
The American journal of physiology 1995;269(3 Pt 1):L285-92.
1995: MacNee W; Rahman I
Oxidants/antioxidants in idiopathic pulmonary fibrosis.
Thorax 1995;50 Suppl 1():S53-8.
1995: Hannah S; Mecklenburgh K; Rahman I; Bellingan G J; Greening A; Haslett C; Chilvers E R
Hypoxia prolongs neutrophil survival in vitro.
FEBS letters 1995;372(2-3):233-7.
1995: Rahman I; Li X Y; Donaldson K; Macnee W
Cigarette smoke, glutathione metabolism and epithelial permeability in rat lungs.
Biochemical Society transactions 1995;23(2):235S.

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