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Antonina Rait

Research Profile

Chemicals & Drugs

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Publications

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Neil Senzer; Minal Barve; Cynthia Bedell; Gerald Edelman; Derek Nemunaitis; John Nemunaitis; Robert Nunan; Kathleen F Pirollo; Antonina Rait; Esther H Chang
Phase I Study of a Systemically Delivered p53 Nanoparticle in Advanced Solid Tumors.
E R Camp; Esther H Chang; David J Cole; E C Little; Kathleen F Pirollo; Antonina Rait; C Wang; Patricia M Watson; Dennis Watson
Transferrin receptor targeting nanomedicine delivering wild-type p53 gene sensitizes pancreatic cancer to gemcitabine therapy.
Chengli Yang; Antonina Rait; Kathleen F Pirollo; John Dagata; Natalia Farkas; Esther H Chang
Nanoimmunoliposome delivery of superparamagnetic iron oxide markedly enhances targeting and uptake in human cancer cells in vitro and in vivo.

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All Publications

2013: Neil Senzer; Minal Barve; Cynthia Bedell; Gerald Edelman; Derek Nemunaitis; John Nemunaitis; Robert Nunan; Kathleen F Pirollo; Antonina Rait; Esther H Chang
Phase I Study of a Systemically Delivered p53 Nanoparticle in Advanced Solid Tumors.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(5):1096-103.
2013: E R Camp; Esther H Chang; David J Cole; E C Little; Kathleen F Pirollo; Antonina Rait; C Wang; Patricia M Watson; Dennis Watson
Transferrin receptor targeting nanomedicine delivering wild-type p53 gene sensitizes pancreatic cancer to gemcitabine therapy.
Cancer gene therapy 2013;20(4):222-8.
2008: Chengli Yang; Antonina Rait; Kathleen F Pirollo; John Dagata; Natalia Farkas; Esther H Chang
Nanoimmunoliposome delivery of superparamagnetic iron oxide markedly enhances targeting and uptake in human cancer cells in vitro and in vivo.
Nanomedicine : nanotechnology, biology, and medicine 2008;4(4):318-29.
2008: Kathleen F Pirollo; Antonina Rait; Qi Zhou; Xin-qiao Zhang; Jain Zhou; Chang-Soo Kim; William F Benedict; Esther H Chang
Tumor-targeting nanocomplex delivery of novel tumor suppressor RB94 chemosensitizes bladder carcinoma cells in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(7):2190-8.
2008: Sung Hee Hwang; Antonina Rait; Kathleen F Pirollo; Qi Zhou; Venkata Mahidhar Yenugonda; Gary M Chinigo; Milton L Brown; Esther H Chang
Tumor-targeting nanodelivery enhances the anticancer activity of a novel quinazolinone analogue.
Molecular cancer therapeutics 2008;7(3):559-68.
2007: Kathleen F Pirollo; Antonina Rait; Qi Zhou; Sung Hee Hwang; John Dagata; Gerald Zon; Richard I Hogrefe; Guillermo Palchik; Esther H Chang
Materializing the potential of small interfering RNA via a tumor-targeting nanodelivery system.
Cancer research 2007;67(7):2938-43.
2006: Richard I Hogrefe; Alexandre V Lebedev; Gerald Zon; Kathleen F Pirollo; Antonina Rait; Qi Zhou; Wei Yu; Esther H Chang
Chemically modified short interfering hybrids (siHYBRIDS): nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2.
Nucleosides, nucleotides & nucleic acids 2006;25(8):889-907.
2006: Kathleen F Pirollo; Gerald Zon; Antonina Rait; Qi Zhou; Wei Yu; Richard I Hogrefe; Esther H Chang
Tumor-targeting nanoimmunoliposome complex for short interfering RNA delivery.
Human gene therapy 2006;17(1):117-24.
2004: Mona S Jhaveri; Antonina Rait; Koong-Nah Chung; Jane Trepel; Esther H Chang
Antisense oligonucleotides targeted to the human alpha folate receptor inhibit breast cancer cell growth and sensitize the cells to doxorubicin treatment.
Molecular cancer therapeutics 2004;3(12):1505-12.
2004: Wei Yu; Kathleen F Pirollo; Antonina Rait; Bin Yu; Lai-Man Xiang; W Q Huang; Qi Zhou; Gözen Ertem; Esther H Chang
A sterically stabilized immunolipoplex for systemic administration of a therapeutic gene.
Gene therapy 2004;11(19):1434-40.
2004: Wei Yu; Kathleen F Pirollo; Bin Yu; Antonina Rait; Laiman Xiang; Weiqun Huang; Qi Zhou; Gözen Ertem; Esther H Chang
Enhanced transfection efficiency of a systemically delivered tumor-targeting immunolipoplex by inclusion of a pH-sensitive histidylated oligolysine peptide.
Nucleic acids research 2004;32(5):e48.
2003: Antonina Rait; Kathleen F Pirollo; David Ulick; Kevin J Cullen; Esther H Chang
HER-2-targeted antisense oligonucleotide results in sensitization of head and neck cancer cells to chemotherapeutic agents.
Annals of the New York Academy of Sciences 2003;1002():78-89.
2003: Kathleen F Pirollo; Antonina Rait; Leanne S Sleer; Esther H Chang
Antisense therapeutics: from theory to clinical practice.
Pharmacology & therapeutics 2003;99(1):55-77.
2002: Antonina Rait; Kathleen F Pirollo; Laiman Xiang; David Ulick; Esther H Chang
Tumor-targeting, systemically delivered antisense HER-2 chemosensitizes human breast cancer xenografts irrespective of HER-2 levels.
Molecular medicine (Cambridge, Mass.) 2002;8(8):475-86.
2002: Liang Xu; Cheng-Cheng Huang; Weiqun Huang; Wen-Hua Tang; Antonina Rait; Yu Zhi Yin; Idalia Cruz; Lai-Man Xiang; Kathleen F Pirollo; Esther H Chang
Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes.
Molecular cancer therapeutics 2002;1(5):337-46.
2002: Liang Xu; Peter M Frederik; Kathleen F Pirollo; Wen-Hua Tang; Antonina Rait; Lai-Man Xiang; Weiqun Huang; Idalia Cruz; Yuzhi Yin; Esther H Chang
Self-assembly of a virus-mimicking nanostructure system for efficient tumor-targeted gene delivery.
Human gene therapy 2002;13(3):469-81.
2001: Liang Xu; Wen-Hua Tang; C C Huang; W Alexander; Lai-Man Xiang; Kathleen F Pirollo; Antonina Rait; Esther H Chang
Systemic p53 gene therapy of cancer with immunolipoplexes targeted by anti-transferrin receptor scFv.
Molecular medicine (Cambridge, Mass.) 2001;7(10):723-34.
2001: Z A Sherif; S Nakai; Kathleen F Pirollo; Antonina Rait; Esther H Chang
Downmodulation of bFGF-binding protein expression following restoration of p53 function.
Cancer gene therapy 2001;8(10):771-82.
2001: Antonina Rait; Kathleen F Pirollo; V Rait; J E Krygier; Laiman Xiang; Esther H Chang
Inhibitory effects of the combination of HER-2 antisense oligonucleotide and chemotherapeutic agents used for the treatment of human breast cancer.
Cancer gene therapy 2001;8(10):728-39.
2000: Antonina Rait; E Uhlmann; Anusch Peyman; David W Will; Esther H Chang
Inhibition of Ras p21 synthesis by antisense undecamers with uniform and specifically arranged phosphorothioate linkages.
Anti-cancer drugs 2000;11(3):181-91.
2000: Antonina Rait; Kathleen F Pirollo; David W Will; Anusch Peyman; V Rait; E Uhlmann; Esther H Chang
3'-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: synthesis and anti-ras activity in radiation-resistant cells.
Bioconjugate chemistry 2000;11(2):153-60.
1999: Liang Xu; Kathleen F Pirollo; Wen-Hua Tang; Antonina Rait; Esther H Chang
Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts.
Human gene therapy 1999;10(18):2941-52.
1997: Esther H Chang; Y J Jang; Z Hao; G Murphy; Antonina Rait; Willard E Fee; Howard H Sussman; P Ryan; Y Chiang; Kathleen F Pirollo
Restoration of the G1 checkpoint and the apoptotic pathway mediated by wild-type p53 sensitizes squamous cell carcinoma of the head and neck to radiotherapy.
Archives of otolaryngology--head & neck surgery 1997;123(5):507-12.
1997: Kathleen F Pirollo; Z Hao; Antonina Rait; Y J Jang; Willard E Fee; P Ryan; Y Chiang; Esther H Chang
p53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy.
Oncogene 1997;14(14):1735-46.
1997: Kathleen F Pirollo; Z Hao; Antonina Rait; C W Ho; Esther H Chang
Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells.
Biochemical and biophysical research communications 1997;230(1):196-201.

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