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Konrad Beyreuther

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Zareen Amtul; Richard Rozmahel; Markus Uhrig; Lin Wang; Konrad Beyreuther
Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight.
Zareen Amtul; Markus Uhrig; Konrad Beyreuther
Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids.
Zareen Amtul; Markus Uhrig; Richard F Rozmahel; Konrad Beyreuther
Structural insight into the differential effects of omega-3 and omega-6 fatty acids on the production of Abeta peptides and amyloid plaques.

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2012: Zareen Amtul; Richard Rozmahel; Markus Uhrig; Lin Wang; Konrad Beyreuther
Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight.
Neurobiology of aging 2012;33(4):831.e21-31.
2011: Zareen Amtul; Markus Uhrig; Konrad Beyreuther
Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids.
Journal of neuroscience research 2011;89(11):1795-801.
2011: Zareen Amtul; Markus Uhrig; Richard F Rozmahel; Konrad Beyreuther
Structural insight into the differential effects of omega-3 and omega-6 fatty acids on the production of Abeta peptides and amyloid plaques.
The Journal of biological chemistry 2011;286(8):6100-7.
2010: Zareen Amtul; Markus Uhrig; Rosanna Supino; Konrad Beyreuther
Phospholipids and a phospholipid-rich diet alter the in vitro amyloid-beta peptide levels and amyloid-beta 42/40 ratios.
Neuroscience letters 2010;481(2):73-7.
2009: Anita Szodorai; Yung-Hui Kuan; Silke Hunzelmann; Ulrike Engel; Ayuko Sakane; Takuya Sasaki; Yoshimi Takai; Joachim Kirsch; Ulrike Müller; Konrad Beyreuther; Scott T Brady; Gerardo Morfini; Stefan Kins
APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(46):14534-44.
2009: J Lv; H Jia; Yong Jiang; Yan Ruan; Zhonghua Liu; W Yue; Konrad Beyreuther; Pengfei Tu; Dai Zhang
Tenuifolin, an extract derived from tenuigenin, inhibits amyloid-beta secretion in vitro.
Acta physiologica (Oxford, England) 2009;196(4):419-25.
2008: Jens Radzimanowski; Bernd Simon; Michael Sattler; Konrad Beyreuther; Irmgard Sinning; Klemens Wild
Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
EMBO reports 2008;9(11):1134-40.
2008: Jens Radzimanowski; Stéphanie Ravaud; Sabine Schlesinger; Joachim Koch; Konrad Beyreuther; Irmgard Sinning; Klemens Wild
Crystal structure of the human Fe65-PTB1 domain.
The Journal of biological chemistry 2008;283(34):23113-20.
2008: Kwok S Wun; Luke A Miles; Gabriela A N Crespi; Kaye Wycherley; David B Ascher; Kevin J Barnham; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Michael W Parker; William J McKinstry
Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 5):438-41.
2008: Jens Radzimanowski; Konrad Beyreuther; Irmgard Sinning; Klemens Wild
Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 5):409-12.
2008: Jens Radzimanowski; Stéphanie Ravaud; Konrad Beyreuther; Irmgard Sinning; Klemens Wild
Mercury-induced crystallization and SAD phasing of the human Fe65-PTB1 domain.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 5):382-5.
2008: Marcus Otto Walter Grimm; Heike S Grimm; Inge Tomic; Konrad Beyreuther; Tobias Hartmann; Christine Bergmann
Independent inhibition of Alzheimer disease beta- and gamma-secretase cleavage by lowered cholesterol levels.
The Journal of biological chemistry 2008;283(17):11302-11.
2008: Luke A Miles; Kwok S Wun; Gabriela A N Crespi; Michelle T Fodero-Tavoletti; Denise Galatis; Christopher J Bagley; Konrad Beyreuther; Colin L Masters; Roberto Cappai; William J McKinstry; Kevin J Barnham; Michael W Parker
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
Journal of molecular biology 2008;377(1):181-92.
2007: Simone Back; Petra Haas; Jakob Tschaepe; Tomas Gruebl; Joachim Kirsch; Ulrike Müller; Konrad Beyreuther; Stefan Kins
beta-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment.
Journal of neuroscience research 2007;85(12):2580-90.
2007: Konrad Beyreuther; H K Biesalski; J D Fernstrom; P Grimm; W P Hammes; U Heinemann; Oliver Kempski; P Stehle; H Steinhart; R Walker
Consensus meeting: monosodium glutamate - an update.
European journal of clinical nutrition 2007;61(3):304-13.
2007: Patricia Rusu; Anna Jansen; Peter Soba; Joachim Kirsch; Alexander Löwer; Gunter Merdes; Yung-Hui Kuan; Anita Jung; Konrad Beyreuther; Ole Kjaerulff; Stefan Kins
Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity.
The European journal of neuroscience 2007;25(4):1079-86.
2006: Yung-Hui Kuan; Tomas Gruebl; Peter Soba; Simone Eggert; Iva Nesic; Simone Back; Joachim Kirsch; Konrad Beyreuther; Stefan Kins
PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2.
The Journal of biological chemistry 2006;281(52):40114-23.
2006: Colin L Masters; Konrad Beyreuther
Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway.
Brain : a journal of neurology 2006;129(Pt 11):2823-39.
2006: Zhonghua Liu; Yan Ruan; Weihua Yue; Zhihui Zhu; Tobias Hartmann; Konrad Beyreuther; Dai Zhang
GM1 up-regulates Ubiquilin 1 expression in human neuroblastoma cells and rat cortical neurons.
Neuroscience letters 2006;407(1):59-63.
2006: Kevin J Barnham; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Andrew Hill
Delineating common molecular mechanisms in Alzheimer's and prion diseases.
Trends in biochemical sciences 2006;31(8):465-72.
2006: Stefan Kins; Konrad Beyreuther
Teasing out the tangles.
Nature medicine 2006;12(7):764-5; discussion 765.
2006: youngdon kwak; CL Brannen; Tingyu Qu; H M Kim; X Dong; Peter Soba; A Majumdar; A Kaplan; Konrad Beyreuther; Kiminobu Sugaya
Amyloid precursor protein regulates differentiation of human neural stem cells.
Stem cells and development 2006;15(3):381-9.
2006: Stefan Kins; Nadine Lauther; Anita Szodorai; Konrad Beyreuther
Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease.
Neuro-degenerative diseases 2006;3(4-5):218-26.
2006: Colin L Masters; Konrad Beyreuther
Pathways to the discovery of the Abeta amyloid of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):155-61.
2005: Leonid Yavich; Mari Oksman; Heikki Tanila; Petri Kerokoski; Mikko Hiltunen; Thomas van Groen; Jukka Puoliväli; Pekka T Männistö; Arturo García-Horsman; Ewen MacDonald; Konrad Beyreuther; Tobias Hartmann; Pekka Jäkälä
Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein.
Neurobiology of disease 2005;20(2):303-13.
2005: Peter Soba; Simone Eggert; Katja Wagner; Hanswalter Zentgraf; Katjuscha Siehl; Sylvia Kreger; Alexander Löwer; Andreas Langer; Gunter Merdes; Renato Paro; Colin L Masters; Ulrike Müller; Stefan Kins; Konrad Beyreuther
Homo- and heterodimerization of APP family members promotes intercellular adhesion.
The EMBO journal 2005;24(20):3624-34.
2004: Gunter Merdes; Peter Soba; Alexander Loewer; Michaela V Bilic; Konrad Beyreuther; Renato Paro
Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila.
The EMBO journal 2004;23(20):4082-95.
2004: Q Zha; Yan Ruan; Tobias Hartmann; Konrad Beyreuther; Dai Zhang
GM1 ganglioside regulates the proteolysis of amyloid precursor protein.
Molecular psychiatry 2004;9(10):946-52.
2004: Kevin J Barnham; Fredrik Haeffner; Giuseppe D Ciccotosto; Cyril C Curtain; Deborah J Tew; Christine Mavros; Konrad Beyreuther; Darryl Carrington; Colin L Masters; Robert A Cherny; Roberto Cappai; Ashley I Bush
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1427-9.
2004: Hongxiao Jia; Yong Jiang; Yan Ruan; Yanbo Zhang; Xin Ma; Jizhi Zhang; Konrad Beyreuther; Penfei Tu; Dai Zhang
Tenuigenin treatment decreases secretion of the Alzheimer's disease amyloid beta-protein in cultured cells.
Neuroscience letters 2004;367(1):123-8.
2004: Amee J George; R. M. Damian Holsinger; Catriona A McLean; Katrina M Laughton; Konrad Beyreuther; Geneviève Evin; Colin L Masters; Qiao-Xin Li
APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease.
Neurobiology of disease 2004;16(1):124-32.
2004: Simone Eggert; Krzysztof Paliga; Peter Soba; Geneviève Evin; Colin L Masters; Andreas Weidemann; Konrad Beyreuther
The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.
The Journal of biological chemistry 2004;279(18):18146-56.
2004: Alexander Loewer; Peter Soba; Konrad Beyreuther; Renato Paro; Gunter Merdes
Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development.
EMBO reports 2004;5(4):405-11.
2004: Anthony R White; Kevin J Barnham; Xudong Huang; Irene Voltakis; Konrad Beyreuther; Colin L Masters; Robert A Cherny; Ashley I Bush; Roberto Cappai
Iron inhibits neurotoxicity induced by trace copper and biological reductants.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(3):269-80.
2004: Klaus Fassbender; Silke Walter; Sandra Kühl; Regine Landmann; K Ishii; Thomas Bertsch; Anna K Stalder; Frank Muehlhauser; Yang Liu; Artur J Ulmer; Serge Rivest; Arnd Lentschat; E Gulbins; Mathias Jucker; Matthias Staufenbiel; Katrin Brechtel; J Walter; Gerd Multhaup; Botond Penke; Y Adachi; Tobias Hartmann; Konrad Beyreuther
The LPS receptor (CD14) links innate immunity with Alzheimer's disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):203-5.
2003: Craig W Ritchie; Ashley I Bush; Andrew Mackinnon; Stephen Macfarlane; Maree Mastwyk; Lachlan MacGregor; Lyn Kiers; Robert A Cherny; Qiao-Xin Li; Amanda Tammer; Darryl Carrington; Christine Mavros; Irene Volitakis; Michel E Xilinas; David Ames; Stephen Davis; Konrad Beyreuther; Rudolph E Tanzi; Colin L Masters
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial.
Archives of neurology 2003;60(12):1685-91.
2003: Ariane Schmechel; Hanswalter Zentgraf; Stefan Scheuermann; Guenter Fritz; Rüdiger Pipkorn; Jennifer Reed; Konrad Beyreuther; Thomas A Bayer; Gerd Multhaup
Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies.
The Journal of biological chemistry 2003;278(37):35317-24.
2003: Kevin J Barnham; William J McKinstry; Gerd Multhaup; Denise Galatis; Craig J Morton; Cyril C Curtain; Nicholas A Williamson; Anthony R White; Mark G Hinds; Raymond S Norton; Konrad Beyreuther; Colin L Masters; Michael W Parker; Roberto Cappai
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.
The Journal of biological chemistry 2003;278(19):17401-7.
2003: Heike S Grimm; Dirk Beher; Stefan F Lichtenthaler; Mark S Shearman; Konrad Beyreuther; Tobias Hartmann
gamma-Secretase cleavage site specificity differs for intracellular and secretory amyloid beta.
The Journal of biological chemistry 2003;278(15):13077-85.
2003: Anthony R White; Fran Maher; Marcus Brazier; Michael F Jobling; James Thyer; Leanne R Stewart; Andrew Thompson; Riki Gibson; Colin L Masters; Gerd Multhaup; Konrad Beyreuther; Colin J Barrow; Steven J Collins; Roberto Cappai
Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation.
Brain research 2003;966(2):231-44.
2003: Bart P F Rutten; Oliver Wirths; Wilma D J Van De Berg; Stefan F Lichtenthaler; Jochen Vehoff; Harry W M Steinbusch; Hubert Korr; Konrad Beyreuther; Gerd Multhaup; Thomas A Bayer; Christoph Schmitz
No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment.
Neurobiology of disease 2003;12(2):110-20.
2003: Beate Grziwa; Marcus Otto Walter Grimm; Colin L Masters; Konrad Beyreuther; Tobias Hartmann; Stefan F Lichtenthaler
The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted.
The Journal of biological chemistry 2003;278(9):6803-8.
2003: M Fleur Sernee; Geneviève Evin; Janetta G Culvenor; Jose A Villadangos; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage.
European journal of biochemistry / FEBS 2003;270(3):495-506.
2003: Amir Gamliel; C Teicher; Tobias Hartmann; Konrad Beyreuther; Reuven Stein
Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines.
Neuroscience 2003;117(1):19-28.
2002: Zeinab Khalil; Helen Poliviou; Christa Maynard; Konrad Beyreuther; Colin L Masters; Qiao-Xin Li
Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein.
Journal of Alzheimer's disease : JAD 2002;4(6):467-78.
2002: Christa Maynard; Roberto Cappai; Irene Volitakis; Robert A Cherny; Anthony R White; Konrad Beyreuther; Colin L Masters; Ashley I Bush; Qiao-Xin Li
Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.
The Journal of biological chemistry 2002;277(47):44670-6.
2002: Mikael Simons; Frank Schwärzler; Dieter Lütjohann; Klaus Von Bergmann; Konrad Beyreuther; Johannes Dichgans; Henning Wormstall; Tobias Hartmann; Jörg B Schulz
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.
Annals of neurology 2002;52(3):346-50.
2002: Qiao-Xin Li; Bruce C V Campbell; Catriona A McLean; Dominic Thyagarajan; Wei Ping Gai; Robert Kapsa; Konrad Beyreuther; Colin L Masters; Janetta G Culvenor
Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects.
Journal of Alzheimer's disease : JAD 2002;4(4):309-15.
2002: Andreas Simons; Thomas Ruppert; Carsten Schmidt; Andrea Schlicksupp; Rüdiger Pipkorn; Jennifer Reed; Colin L Masters; Anthony R White; Roberto Cappai; Konrad Beyreuther; Thomas A Bayer; Gerd Multhaup
Evidence for a copper-binding superfamily of the amyloid precursor protein.
Biochemistry 2002;41(30):9310-20.
2002: Oliver Wirths; Gerd Multhaup; Christian Czech; Nicole Feldmann; Véronique Blanchard; Günter Tremp; Konrad Beyreuther; Laurent Pradier; Thomas A Bayer
Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice.
Brain pathology (Zurich, Switzerland) 2002;12(3):275-86.
2002: Dieter Lütjohann; Andreas Brzezinka; Esther Barth; Dorothee Abramowski; Matthias Staufenbiel; Klaus Von Bergmann; Konrad Beyreuther; Gerd Multhaup; Thomas A Bayer
Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain.
Journal of lipid research 2002;43(7):1078-85.
2002: John A Hamilton; Genevieve A Whitty; Anthony R White; Michael F Jobling; Andrew Thompson; Colin J Barrow; Roberto Cappai; Konrad Beyreuther; Colin L Masters
Alzheimer's disease amyloid beta and prion protein amyloidogenic peptides promote macrophage survival, DNA synthesis and enhanced proliferative response to CSF-1 (M-CSF).
Brain research 2002;940(1-2):49-54.
2002: R. M. Damian Holsinger; Catriona A McLean; Konrad Beyreuther; Colin L Masters; Geneviève Evin
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease.
Annals of neurology 2002;51(6):783-6.
2002: Su San Mok; Bradley J Turner; Konrad Beyreuther; Colin L Masters; Colin J Barrow; David Small
Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine.
European journal of biochemistry / FEBS 2002;269(12):3014-22.
2002: Peter Schönknecht; Dieter Lütjohann; Johannes Pantel; Hubert J Bardenheuer; Tobias Hartmann; Klaus Von Bergmann; Konrad Beyreuther; Johannes Schröder
Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls.
Neuroscience letters 2002;324(1):83-5.
2002: Geneviève Evin; Margaret J Smith; Angela Tziotis; Catriona McLean; Louise Canterford; Robyn A Sharples; Roberto Cappai; Andreas Weidemann; Konrad Beyreuther; Richard G H Cotton; Colin L Masters; Janetta G Culvenor
Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Neuroreport 2002;13(6):917-21.
2002: Lisa R Fodero; Javier Sáez-Valero; Catriona A McLean; Ralph N Martins; Konrad Beyreuther; Colin L Masters; Terry A Robertson; David Small
Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition.
Journal of neurochemistry 2002;81(3):441-8.
2002: Geneviève Evin; Margaret J Smith; Angela Tziotis; Catriona McLean; Louise Canterford; Robyn A Sharples; Roberto Cappai; Andreas Weidemann; Konrad Beyreuther; Richard G H Cotton; Colin L Masters; Janetta G Culvenor
Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Neuroreport 2002;13(5):719-23.
2002: Heiko Runz; Jens Rietdorf; Inge Tomic; Marina de Bernard; Konrad Beyreuther; Rainer Pepperkok; Tobias Hartmann
Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(5):1679-89.
2002: Andreas Weidemann; Simone Eggert; Friedrich B M Reinhard; Markus Vogel; Krzysztof Paliga; Gottfried Baier; Colin L Masters; Konrad Beyreuther; Geneviève Evin
A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing.
Biochemistry 2002;41(8):2825-35.
2002: Stefan F Lichtenthaler; Dirk Beher; Heike S Grimm; Rong Wang; Mark S Shearman; Colin L Masters; Konrad Beyreuther
The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1365-70.
2002: Anthony R White; Gerd Multhaup; Denise Galatis; William J McKinstry; Michael W Parker; Rüdiger Pipkorn; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(2):365-76.
2002: Amir Gamliel; Carmit Teicher; Daniel M Michaelson; Laurent Pradier; Tobias Hartmann; Konrad Beyreuther; Reuven Stein
Increased expression of presenilin 2 inhibits protein synthesis.
Molecular and cellular neurosciences 2002;19(1):111-24.
2001: Oliver Wirths; Gerd Multhaup; Christian Czech; Véronique Blanchard; Günter Tremp; Laurent Pradier; Konrad Beyreuther; Thomas A Bayer
Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice.
Neuroscience letters 2001;316(3):145-8.
2001: Janelle Nunan; Mark S Shearman; F Checler; Roberto Cappai; Geneviève Evin; Konrad Beyreuther; Colin L Masters; David Small
The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
European journal of biochemistry / FEBS 2001;268(20):5329-36.
2001: Leanne R Stewart; Anthony R White; Michael F Jobling; B Elise Needham; Fran Maher; James Thyer; Konrad Beyreuther; Colin L Masters; Steven J Collins; Roberto Cappai
Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126.
Journal of neuroscience research 2001;65(6):565-72.
2001: Stefan Scheuermann; B Hambsch; L Hesse; J Stumm; C Schmidt; Dirk Beher; Thomas A Bayer; Konrad Beyreuther; Gerd Multhaup
Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease.
The Journal of biological chemistry 2001;276(36):33923-9.
2001: Geneviève Evin; Robyn A Sharples; Andreas Weidemann; Friedrich B M Reinhard; V Carbone; Janetta G Culvenor; R. M. Damian Holsinger; M Fleur Sernee; Konrad Beyreuther; Colin L Masters
Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.
Biochemistry 2001;40(28):8359-68.
2001: Oliver Wirths; Gerd Multhaup; Christian Czech; Véronique Blanchard; Saliha Moussaoui; Günter Tremp; Laurent Pradier; Konrad Beyreuther; Thomas A Bayer
Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.
Neuroscience letters 2001;306(1-2):116-20.
2001: Cyril C Curtain; F Ali; Irene Volitakis; Robert A Cherny; Raymond S Norton; Konrad Beyreuther; Colin J Barrow; Colin L Masters; Ashley I Bush; Kevin J Barnham
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits.
The Journal of biological chemistry 2001;276(23):20466-73.
2001: K Fassbender; Colin L Masters; Konrad Beyreuther
Alzheimer's disease: molecular concepts and therapeutic targets.
Die Naturwissenschaften 2001;88(6):261-7.
2001: Robert A Cherny; Craig S Atwood; Michel E Xilinas; D N Gray; Walton D Jones; Catriona A McLean; Kevin J Barnham; Irene Volitakis; Fiona Fraser; Y Kim; Xudong Huang; Lee E Goldstein; Robert D. Moir; JT Lim; Konrad Beyreuther; Hui Zheng; Rudolph E Tanzi; Colin L Masters; Ashley I Bush
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.
Neuron 2001;30(3):665-76.
2001: Klaus Fassbender; M Simons; C Bergmann; Mark Stroick; D Lutjohann; P Keller; H Runz; S Kuhl; Thomas Bertsch; Klaus Von Bergmann; Michael Hennerici; Konrad Beyreuther; Tobias Hartmann
Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5856-61.
2001: U L Jayasena; S K Gribble; A McKenzie; Konrad Beyreuther; Colin L Masters; J R Underwood
Identification of structural variations in the carboxyl terminus of Alzheimer's disease-associated beta A4[1-42] amyloid using a monoclonal antibody.
Clinical and experimental immunology 2001;124(2):297-305.
2001: Colin L Masters; Konrad Beyreuther
The Worster-Drought syndrome and other syndromes of dementia with spastic paraparesis: the paradox of molecular pathology.
Journal of neuropathology and experimental neurology 2001;60(4):317-9.
2001: Anthony R White; R Guirguis; Marcus Brazier; Michael F Jobling; Andrew Hill; Konrad Beyreuther; Colin J Barrow; Colin L Masters; Steven J Collins; Roberto Cappai
Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons.
Neurobiology of disease 2001;8(2):299-316.
2001: Anthony R White; Xudong Huang; Michael F Jobling; Colin J Barrow; Konrad Beyreuther; Colin L Masters; Ashley I Bush; Roberto Cappai
Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways.
Journal of neurochemistry 2001;76(5):1509-20.
2001: Bruce C V Campbell; Catriona A McLean; Janetta G Culvenor; Wei Ping Gai; Peter C Blumbergs; P Jäkälä; Konrad Beyreuther; Colin L Masters; Qiao-Xin Li
The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease.
Journal of neurochemistry 2001;76(1):87-96.
2001: Thomas A Bayer; Oliver Wirths; K Majtényi; Tobias Hartmann; Gerd Multhaup; Konrad Beyreuther; Christian Czech
Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport.
Brain pathology (Zurich, Switzerland) 2001;11(1):1-11.
2000: Oliver Wirths; S Weickert; K Majtenyi; L Havas; Philipp J Kahle; Masayasu Okochi; Christian Haass; Gerd Multhaup; Konrad Beyreuther; Thomas A Bayer
Lewy body variant of Alzheimer's disease: alpha-synuclein in dystrophic neurites of A beta plaques.
Neuroreport 2000;11(17):3737-41.
2000: P Schonknecht; Johannes Pantel; Egon Werle; Tobias Hartmann; Marco Essig; Klaus T Baudendistel; Konrad Beyreuther; Johannes Schroder
[Cerebrospinal fluid protein tau levels in the differential diagnosis of Alzheimer's disease].
Fortschritte der Neurologie-Psychiatrie 2000;68(10):439-46.
2000: C Leloup; Daniel M Michaelson; Abraham Fisher; Tobias Hartmann; Konrad Beyreuther; Reuven Stein
M1 muscarinic receptors block caspase activation by phosphoinositide 3-kinase- and MAPK/ERK-independent pathways.
Cell death and differentiation 2000;7(9):825-33.
2000: Su San Mok; Andrew B Clippingdale; Konrad Beyreuther; Colin L Masters; Colin J Barrow; David Small
A beta peptides and calcium influence secretion of the amyloid protein precursor from chick sympathetic neurons in culture.
Journal of neuroscience research 2000;61(4):449-57.
2000: K Ishii; F Muelhauser; U Liebl; M Picard; Sandra Kühl; Botond Penke; Thomas A Bayer; M Wiessler; Michael Hennerici; Konrad Beyreuther; Tobias Hartmann; Klaus Fassbender
Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(11):1485-9.
2000: Robert A Cherny; Kevin J Barnham; T Lynch; Irene Volitakis; Qiao-Xin Li; Catriona A McLean; Gerd Multhaup; Konrad Beyreuther; Rudolph E Tanzi; Colin L Masters; Ashley I Bush
Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease.
Journal of structural biology 2000;130(2-3):209-16.
2000: Thilo Borchardt; C Schmidt; J Camarkis; Roberto Cappai; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
Differential effects of zinc on amyloid precursor protein (APP) processing in copper-resistant variants of cultured Chinese hamster ovary cells.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(4):785-95.
2000: Bruce C V Campbell; Qiao-Xin Li; Janetta G Culvenor; P Jäkälä; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Catriona A McLean
Accumulation of insoluble alpha-synuclein in dementia with Lewy bodies.
Neurobiology of disease 2000;7(3):192-200.
2000: K Fassbender; Colin L Masters; Konrad Beyreuther
Alzheimer's disease: an inflammatory disease?
Neurobiology of aging 2000;21(3):433-6; discussion 451-3.
2000: M Jensen; Tobias Hartmann; Benita Engvall; Rong Wang; S N Uljon; Kristina Sennvik; Jan Näslund; F Muehlhauser; C Nordstedt; Konrad Beyreuther; Lars Lannfelt
Quantification of Alzheimer amyloid beta peptides ending at residues 40 and 42 by novel ELISA systems.
Molecular medicine (Cambridge, Mass.) 2000;6(4):291-302.
2000: G Emilien; Konrad Beyreuther; Colin L Masters; Jean-Marie Maloteaux
Prospects for pharmacological intervention in Alzheimer disease.
Archives of neurology 2000;57(4):454-9.
2000: R K Uhrig; M A Picard; Konrad Beyreuther; M Wiessler
Synthesis of antioxidative and anti-inflammatory drugs glucoconjugates.
Carbohydrate research 2000;325(1):72-80.
2000: Janetta G Culvenor; Geneviève Evin; M A Cooney; H Wardan; Robyn A Sharples; Fran Maher; G Reed; A Diehlmann; Andreas Weidemann; Konrad Beyreuther; Colin L Masters
Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells.
Experimental cell research 2000;255(2):192-206.
2000: Margaret J Smith; KE Humphrey; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Richard G H Cotton
Correct heteroduplex formation for mutation detection analysis.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 2000;5(1):67-73.
2000: RB Postuma; W He; Janelle Nunan; Konrad Beyreuther; Colin L Masters; Colin J Barrow; David Small
Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures.
Journal of neurochemistry 2000;74(3):1122-30.
2000: Elizabeth J Coulson; K Paliga; Konrad Beyreuther; Colin L Masters
What the evolution of the amyloid protein precursor supergene family tells us about its function.
Neurochemistry international 2000;36(3):175-84.
2000: Geneviève Evin; D Le Brocque; Janetta G Culvenor; Denise Galatis; Andreas Weidemann; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Presenilin I expression in yeast lowers secretion of the amyloid precursor protein.
Neuroreport 2000;11(2):405-8.
2000: G Emilien; Jean-Marie Maloteaux; Konrad Beyreuther; Colin L Masters
Alzheimer disease: mouse models pave the way for therapeutic opportunities.
Archives of neurology 2000;57(2):176-81.
2000: John B J Kwok; Q X Li; Marianne Hallupp; S Whyte; D Ames; Konrad Beyreuther; Colin L Masters; Peter R Schofield
Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis.
Annals of neurology 2000;47(2):249-53.
2000: C Bergsdorf; Krzysztof Paliga; Sylvia Kreger; Colin L Masters; Konrad Beyreuther
Identification of cis-elements regulating exon 15 splicing of the amyloid precursor protein pre-mRNA.
The Journal of biological chemistry 2000;275(3):2046-56.
2000: Colin L Masters; Konrad Beyreuther
Genomic neurology.
Archives of neurology 2000;57(1):53.
1999: Catriona A McLean; Robert A Cherny; Fiona Fraser; Stephanie J Fuller; M J Smith; Konrad Beyreuther; Ashley I Bush; Colin L Masters
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.
Annals of neurology 1999;46(6):860-6.
1999: Thilo Borchardt; James Camakaris; Roberto Cappai; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion.
The Biochemical journal 1999;344 Pt 2():461-7.
1999: M D Caswell; Su San Mok; A Henry; Roberto Cappai; G Klug; Konrad Beyreuther; Colin L Masters; David Small
The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons.
European journal of biochemistry / FEBS 1999;266(2):509-16.
1999: David Small; H L Clarris; T G Williamson; G Reed; Brian Key; Su San Mok; Konrad Beyreuther; Colin L Masters; V Nurcombe
Neurite-outgrowth regulating functions of the amyloid protein precursor of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 1999;1(4-5):275-85.
1999: T A Bayer; Roberto Cappai; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
It all sticks together--the APP-related family of proteins and Alzheimer's disease.
Molecular psychiatry 1999;4(6):524-8.
1999: Anthony R White; Steven J Collins; Fran Maher; Michael F Jobling; Leanne R Stewart; James Thyer; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity.
The American journal of pathology 1999;155(5):1723-30.
1999: Anthony R White; Gerd Multhaup; Fran Maher; Shayne A Bellingham; James Camakaris; Hui Zheng; Ashley I Bush; Konrad Beyreuther; Colin L Masters; Roberto Cappai
The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(21):9170-9.
1999: Q X Li; Stephanie J Fuller; Konrad Beyreuther; Colin L Masters
The amyloid precursor protein of Alzheimer disease in human brain and blood.
Journal of leukocyte biology 1999;66(4):567-74.
1999: Janetta G Culvenor; Catriona A McLean; S Cutt; Bruce C V Campbell; Fran Maher; P Jäkälä; Tobias Hartmann; Konrad Beyreuther; Colin L Masters; Qiao-Xin Li
Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.
The American journal of pathology 1999;155(4):1173-81.
1999: Michael F Jobling; Leanne R Stewart; Anthony R White; C McLean; Anna Friedhuber; Fran Maher; Konrad Beyreuther; Colin L Masters; Colin J Barrow; Steven J Collins; Roberto Cappai
The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126.
Journal of neurochemistry 1999;73(4):1557-65.
1999: Anthony R White; R Reyes; Julian F B Mercer; James Camakaris; Hui Zheng; Ashley I Bush; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice.
Brain research 1999;842(2):439-44.
1999: Thomas A Bayer; P Jäkälä; Tobias Hartmann; R Egensperger; R Buslei; Peter Falkai; Konrad Beyreuther
Neural expression profile of alpha-synuclein in developing human cortex.
Neuroreport 1999;10(13):2799-803.
1999: Robert A Cherny; J T Legg; Catriona A McLean; D P Fairlie; Xudong Huang; Craig S Atwood; Konrad Beyreuther; Rudolph E Tanzi; Colin L Masters; Ashley I Bush
Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.
The Journal of biological chemistry 1999;274(33):23223-8.
1999: Graham R Christie; RE Markwell; Carol W Gray; L Smith; F Godfrey; F Mansfield; H Wadsworth; R King; M McLaughlin; D G Cooper; RV Ward; David R Howlett; Tobias Hartmann; S F Lichtenthaler; Konrad Beyreuther; J Underwood; S K Gribble; Roberto Cappai; Colin L Masters; A Tamaoka; R L Gardner; A Jennifer Rivett; EH Karran; D Allsop
Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.
Journal of neurochemistry 1999;73(1):195-204.
1999: Stefan F Lichtenthaler; Gerd Multhaup; Colin L Masters; Konrad Beyreuther
A novel substrate for analyzing Alzheimer's disease gamma-secretase.
FEBS letters 1999;453(3):288-92.
1999: Colin L Masters; Konrad Beyreuther
Amyloid Nomenclature Committee.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(2):151-2.
1999: Qiao-Xin Li; C Maynard; Roberto Cappai; Catriona A McLean; Robert A Cherny; T Lynch; Janetta G Culvenor; J Trevaskis; JE Tanner; K A Bailey; C Czech; Ashley I Bush; Konrad Beyreuther; Colin L Masters
Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice.
Journal of neurochemistry 1999;72(6):2479-87.
1999: A Diehlmann; N Ida; Sascha Weggen; J Grünberg; Christian Haass; Colin L Masters; Thomas A Bayer; Konrad Beyreuther
Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
Journal of neuroscience research 1999;56(4):405-19.
1999: Thomas A Bayer; P Jäkälä; Tobias Hartmann; L Havas; C McLean; Janetta G Culvenor; Qiao-Xin Li; Colin L Masters; Peter Falkai; Konrad Beyreuther
Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.
Neuroscience letters 1999;266(3):213-6.
1999: Anthony R White; Ashley I Bush; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione.
Journal of neurochemistry 1999;72(5):2092-8.
1999: E Storey; M Katz; Y Brickman; Konrad Beyreuther; Colin L Masters
Amyloid precursor protein of Alzheimer's disease: evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures.
The European journal of neuroscience 1999;11(5):1779-88.
1999: M Jensen; J Schröder; M Blomberg; Benita Engvall; J Pantel; N Ida; Hans Basun; Lars-Olof Wahlund; Egon Werle; Marek Jauss; Konrad Beyreuther; Lars Lannfelt; Tobias Hartmann
Cerebrospinal fluid A beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression.
Annals of neurology 1999;45(4):504-11.
1999: Jamie Rossjohn; Roberto Cappai; Susanne C Feil; A Henry; William J McKinstry; Denise Galatis; L Hesse; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Michael W Parker
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein.
Nature structural biology 1999;6(4):327-31.
1999: Dirk Beher; C Elle; J Underwood; John B Davis; R Ward; EH Karran; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain.
Journal of neurochemistry 1999;72(4):1564-73.
1999: B P Connop; RL Thies; Konrad Beyreuther; N Ida; Peter B Reiner
Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing.
Journal of neurochemistry 1999;72(4):1457-65.
1999: Roberto Cappai; L Stewart; Michael F Jobling; James Thyer; Anthony R White; Konrad Beyreuther; Steven J Collins; Colin L Masters; Colin J Barrow
Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: implications for the mechanism of prion formation.
Biochemistry 1999;38(11):3280-4.
1999: Stefan F Lichtenthaler; Rong Wang; Heike S Grimm; S N Uljon; Colin L Masters; Konrad Beyreuther
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3053-8.
1999: Margaret J Smith; R J McKinlay Gardner; Melanie A Knight; Susan M Forrest; Konrad Beyreuther; Elsdon Storey; Catriona A McLean; Richard G H Cotton; R Cappal; Colin L Masters
Early-onset Alzheimer's disease caused by a novel mutation at codon 219 of the presenilin-1 gene.
Neuroreport 1999;10(3):503-7.
1999: R Egensperger; Sascha Weggen; N Ida; Gerd Multhaup; R Schnabel; Konrad Beyreuther; Thomas A Bayer
Reverse relationship between beta-amyloid precursor protein and beta-amyloid peptide plaques in Down's syndrome versus sporadic/familial Alzheimer's disease.
Acta neuropathologica 1999;97(2):113-8.
1999: Roberto Cappai; Su San Mok; Denise Galatis; David Tucker; A Henry; Konrad Beyreuther; David Small; Colin L Masters
Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth.
FEBS letters 1999;442(1):95-8.
1999: Y Yang; Konrad Beyreuther; Horst Peter Schmitt
Spatial analysis of the neuronal density of aminergic brainstem nuclei in primary neurodegenerative and vascular dementia: a comparative immunocytochemical and quantitative study using a graph method.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1999;19(3-4):125-38.
1999: RF Ren; James J Lah; A Diehlmann; E S Kim; DB Hawver; Allan Levey; Konrad Beyreuther; Kathleen C Flanders
Differential effects of transforming growth factor-beta(s) and glial cell line-derived neurotrophic factor on gene expression of presenilin-1 in human post-mitotic neurons and astrocytes.
Neuroscience 1999;93(3):1041-9.
1999: Gerd Multhaup; L Hesse; Thilo Borchardt; Thomas Ruppert; Roberto Cappai; Colin L Masters; Konrad Beyreuther
Autoxidation of amyloid precursor protein and formation of reactive oxygen species.
Advances in experimental medicine and biology 1999;448():183-92.
1998: Giuseppina Tesco; TW Kim; A Diehlmann; Konrad Beyreuther; Rudolph E Tanzi
Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.
The Journal of biological chemistry 1998;273(51):33909-14.
1998: A Fossgreen; B Brückner; C Czech; Colin L Masters; Konrad Beyreuther; Renato Paro
Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13703-8.
1998: A Henry; Qiao-Xin Li; Denise Galatis; L Hesse; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.
British journal of haematology 1998;103(2):402-15.
1998: D Le Brocque; A Henry; Roberto Cappai; Qiao-Xin Li; JE Tanner; Denise Galatis; C Gray; S Holmes; JR Underwood; Konrad Beyreuther; Colin L Masters; Geneviève Evin
Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
Biochemistry 1998;37(42):14958-65.
1998: Sascha Weggen; A Diehlmann; R Buslei; Konrad Beyreuther; Thomas A Bayer
Prominent expression of presenilin-1 in senile plaques and reactive astrocytes in Alzheimer's disease brain.
Neuroreport 1998;9(14):3279-83.
1998: Anthony R White; Hui Zheng; Denise Galatis; Fran Maher; L Hesse; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(16):6207-17.
1998: G Sberna; Javier Sáez-Valero; Qiao-Xin Li; C Czech; Konrad Beyreuther; Colin L Masters; Catriona A McLean; David Small
Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease.
Journal of neurochemistry 1998;71(2):723-31.
1998: S Rondot; KG Anthony; Stefan Dübel; N Ida; Stefan Wiemann; Konrad Beyreuther; Laura S Frost; Melvyn Little; Frank Breitling
Epitopes fused to F-pilin are incorporated into functional recombinant pili.
Journal of molecular biology 1998;279(3):589-603.
1998: Janetta G Culvenor; A Henry; Tobias Hartmann; Geneviève Evin; Denise Galatis; Anna Friedhuber; U L Jayasena; JR Underwood; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Subcellular localization of the Alzheimer's disease amyloid precursor protein and derived polypeptides expressed in a recombinant yeast system.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(2):79-89.
1998: S Hass; Friedrich Fresser; Silvano Köchl; Konrad Beyreuther; Gerd Utermann; Gottfried Baier
Physical interaction of ApoE with amyloid precursor protein independent of the amyloid Abeta region in vitro.
The Journal of biological chemistry 1998;273(22):13892-7.
1998: M Simons; P Keller; Bart De Strooper; Konrad Beyreuther; Carlos G Dotti; Kai Simons
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6460-4.
1998: RB Postuma; Ralph N Martins; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Dudley K Strickland; Su San Mok; David Small
Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture.
FEBS letters 1998;428(1-2):13-6.
1998: Gerd Multhaup; Thomas Ruppert; Andrea Schlicksupp; L Hesse; E Bill; Rüdiger Pipkorn; Colin L Masters; Konrad Beyreuther
Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide.
Biochemistry 1998;37(20):7224-30.
1998: Qiao-Xin Li; S Whyte; JE Tanner; Geneviève Evin; Konrad Beyreuther; Colin L Masters
Secretion of Alzheimer's disease Abeta amyloid peptide by activated human platelets.
Laboratory investigation; a journal of technical methods and pathology 1998;78(4):461-9.
1998: D Zhang; Y Ruan; Konrad Beyreuther
[Effect of ganglioside GM1 on the metabolism of Alzheimer amyloid beta-protein precursor].
Zhonghua yi xue za zhi 1998;78(3):179-82.
1998: Robert D. Moir; T Lynch; Ashley I Bush; S Whyte; A Henry; S Portbury; Gerd Multhaup; David Small; Rudolph E Tanzi; Konrad Beyreuther; Colin L Masters
Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.
The Journal of biological chemistry 1998;273(9):5013-9.
1998: Colin L Masters; Konrad Beyreuther
Alzheimer's disease.
BMJ (Clinical research ed.) 1998;316(7129):446-8.
1998: Anja Capell; J Grünberg; B Pesold; A Diehlmann; Martin Citron; Ralph A. Nixon; Konrad Beyreuther; Dennis J Selkoe; Christian Haass
The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex.
The Journal of biological chemistry 1998;273(6):3205-11.
1998: Christoph Hock; S Golombowski; Franz Müller-Spahn; W Naser; Konrad Beyreuther; U Mönning; Dale Schenk; C Vigo-Pelfrey; Ashley I Bush; Robert D. Moir; Rudolph E Tanzi; John H Growdon; Roger M Nitsch
Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity.
European neurology 1998;39(2):111-8.
1998: F Hentschel; R Zerfass; G Becker; Konrad Beyreuther; hans förstl
[Neuroradiological findings in Alzheimer dementia with the presenile mutation].
RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 1998;168(1):97-100.
1997: Julia Mills; D Laurent Charest; F Lam; Konrad Beyreuther; N Ida; S L Pelech; Peter B Reiner
Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(24):9415-22.
1997: Stefan F Lichtenthaler; N Ida; Gerd Multhaup; Colin L Masters; Konrad Beyreuther
Mutations in the transmembrane domain of APP altering gamma-secretase specificity.
Biochemistry 1997;36(49):15396-403.
1997: Thomas A Bayer; Krzysztof Paliga; Sascha Weggen; Otmar D Wiestler; Konrad Beyreuther; Gerd Multhaup
Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer's disease.
Acta neuropathologica 1997;94(6):519-24.
1997: Krzysztof Paliga; G Peraus; Sylvia Kreger; U Dürrwang; L Hesse; Gerd Multhaup; Colin L Masters; Konrad Beyreuther; Andreas Weidemann
Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid.
European journal of biochemistry / FEBS 1997;250(2):354-63.
1997: Konrad Beyreuther; Colin L Masters
Alzheimer's disease. The ins and outs of amyloid-beta.
Nature 1997;389(6652):677-8.
1997: G C Peraus; Colin L Masters; Konrad Beyreuther
Late compartments of amyloid precursor protein transport in SY5Y cells are involved in beta-amyloid secretion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(20):7714-24.
1997: Su San Mok; G Sberna; D Heffernan; Roberto Cappai; Denise Galatis; Heidi J Clarris; William H Sawyer; Konrad Beyreuther; Colin L Masters; David Small
Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease.
FEBS letters 1997;415(3):303-7.
1997: Elizabeth J Coulson; Graham L Barrett; Elsdon Storey; Perry F Bartlett; Konrad Beyreuther; Colin L Masters
Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.
Brain research 1997;770(1-2):72-80.
1997: J Schröder; Johannes Pantel; N Ida; M Essig; Tobias Hartmann; M V Knopp; L R Schad; R Sandbrink; H Sauer; Colin L Masters; Konrad Beyreuther
Cerebral changes and cerebrospinal fluid beta-amyloid in Alzheimer's disease: a study with quantitative magnetic resonance imaging.
Molecular psychiatry 1997;2(6):505-7.
1997: Janetta G Culvenor; Fran Maher; Geneviève Evin; F Malchiodi-Albedi; Roberto Cappai; JR Underwood; J B Davis; E H Karran; G W Roberts; Konrad Beyreuther; Colin L Masters
Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.
Journal of neuroscience research 1997;49(6):719-31.
1997: Gerd Multhaup; Thomas Ruppert; Andrea Schlicksupp; L Hesse; Dirk Beher; Colin L Masters; Konrad Beyreuther
Reactive oxygen species and Alzheimer's disease.
Biochemical pharmacology 1997;54(5):533-9.
1997: Tobias Hartmann; S C Bieger; Barbara Brühl; P J Tienari; N Ida; D Allsop; G W Roberts; Colin L Masters; C G Dotti; Klaus Unsicker; Konrad Beyreuther
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.
Nature medicine 1997;3(9):1016-20.
1997: G Sberna; Javier Sáez-Valero; Konrad Beyreuther; Colin L Masters; David Small
The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells.
Journal of neurochemistry 1997;69(3):1177-84.
1997: Colin L Masters; Konrad Beyreuther
Spongiform encephalopathies. Tracking turncoat prion proteins.
Nature 1997;388(6639):228-9.
1997: Catriona A McLean; Konrad Beyreuther; Colin L Masters
Commentary on the consensus recommendations for the post mortem diagnosis of Alzheimer's disease.
Neurobiology of aging 1997;18(4 Suppl):S89-90.
1997: A Henry; Colin L Masters; Konrad Beyreuther; Roberto Cappai
Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization.
Protein expression and purification 1997;10(2):283-91.
1997: Christian Czech; P Delaère; AF Macq; Michel Reibaud; S Dreisler; Nathalie Touchet; Brigitte Schombert; M Mazadier; Luc Mercken; M Theisen; Laurent Pradier; Jean-Noël Octave; Konrad Beyreuther; Günter Tremp
Proteolytical processing of mutated human amyloid precursor protein in transgenic mice.
Brain research. Molecular brain research 1997;47(1-2):108-16.
1997: Konrad Beyreuther; Colin L Masters
Serpents on the road to dementia and death. Accumulating evidence from several studies points to the normal function of presenilin 1 and suggests how the mutant protein contributes to deposition of amyloid plaques in Alzheimer's disease.
Nature medicine 1997;3(7):723-5.
1997: P J Tienari; N Ida; E Ikonen; M Simons; Andreas Weidemann; Gerd Multhaup; Colin L Masters; C G Dotti; Konrad Beyreuther
Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4125-30.
1997: Andreas Weidemann; Krzysztof Paliga; U Dürrwang; C Czech; Geneviève Evin; Colin L Masters; Konrad Beyreuther
Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein.
Nature medicine 1997;3(3):328-32.
1997: Heidi J Clarris; Roberto Cappai; D Heffernan; Konrad Beyreuther; Colin L Masters; David Small
Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping.
Journal of neurochemistry 1997;68(3):1164-72.
1997: Su San Mok; Geneviève Evin; Qiao-Xin Li; A I Smith; Konrad Beyreuther; Colin L Masters; David Small
A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments.
Biochemistry 1997;36(1):156-63.
1997: S Whyte; N Wilson; Jon Currie; Paul Maruff; V Malone; Ruxsana Shafiq-Antonacci; P Tyler; K L Derry; J Underwood; Q X Li; Konrad Beyreuther; Colin L Masters
Collection and normal levels of the amyloid precursor protein in plasma.
Annals of neurology 1997;41(1):121-4.
1997: R Sandbrink; U Mönning; Colin L Masters; Konrad Beyreuther
Expression of the APP gene family in brain cells, brain development and aging.
Gerontology 1997;43(1-2):119-31.
1997: B Drache; G E Diehl; Konrad Beyreuther; L S Perlmutter; G König
Bcl-xl-specific antibody labels activated microglia associated with Alzheimer's disease and other pathological states.
Journal of neuroscience research 1997;47(1):98-108.
1996: T G Williamson; Su San Mok; A Henry; Roberto Cappai; A D Lander; V Nurcombe; Konrad Beyreuther; Colin L Masters; David Small
Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth.
The Journal of biological chemistry 1996;271(49):31215-21.
1996: R Sandbrink; Konrad Beyreuther
Unraveling the molecular pathway of Alzheimer's disease: research about presenilins gathers momentum.
Molecular psychiatry 1996;1(6):438-44.
1996: Konrad Beyreuther; Colin L Masters
Alzheimer's disease. Tangle disentanglement.
Nature 1996;383(6600):476-7.
1996: E Storey; Konrad Beyreuther; Colin L Masters
Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components.
Brain research 1996;735(2):217-31.
1996: P J Tienari; Bart De Strooper; E Ikonen; M Simons; Andreas Weidemann; C Czech; Tobias Hartmann; N Ida; Gerd Multhaup; Colin L Masters; Fred Van Leuven; Konrad Beyreuther; Carlos G Dotti
The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein.
The EMBO journal 1996;15(19):5218-29.
1996: E Storey; Timothy P Spurck; Jeremy D Pickett-Heaps; Konrad Beyreuther; Colin L Masters
The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites.
Brain research 1996;735(1):59-66.
1996: N Ida; Colin L Masters; Konrad Beyreuther
Rapid cellular uptake of Alzheimer amyloid betaA4 peptide by cultured human neuroblastoma cells.
FEBS letters 1996;394(2):174-8.
1996: N Ida; Tobias Hartmann; Johannes Pantel; Johannes Schröder; R Zerfass; hans förstl; R Sandbrink; Colin L Masters; Konrad Beyreuther
Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.
The Journal of biological chemistry 1996;271(37):22908-14.
1996: hans förstl; H Sattel; M Sarochan; C Besthom; C Czech; S Daniel; C Geiger-Kabisch; F Hentschel; R Zerfass; Konrad Beyreuther
[Alzheimer dementia and normal aging. Clinical, neuroradiologic, neurophysiologic and molecular biology follow-up data].
Der Nervenarzt 1996;67(9):730-8.
1996: Thomas A Bayer; A Fossgreen; C Czech; Konrad Beyreuther; Otmar D Wiestler
Plaque formation in brain transplants exposed to human beta-amyloid precursor protein 695.
Acta neuropathologica 1996;92(2):130-7.
1996: R Sandbrink; D Zhang; S Schaeffer; Colin L Masters; J Bauer; hans förstl; Konrad Beyreuther
Missense mutations of the PS-1/S182 gene in German early-onset Alzheimer's disease patients.
Annals of neurology 1996;40(2):265-6.
1996: Tobias Hartmann; C Bergsdorf; R Sandbrink; P J Tienari; Gerd Multhaup; N Ida; S Bieger; T Dyrks; Andreas Weidemann; Colin L Masters; Konrad Beyreuther
Alzheimer's disease betaA4 protein release and amyloid precursor protein sorting are regulated by alternative splicing.
The Journal of biological chemistry 1996;271(22):13208-14.
1996: Gerd Multhaup; Andrea Schlicksupp; L Hesse; Dirk Beher; T Ruppert; Colin L Masters; Konrad Beyreuther
The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
Science (New York, N.Y.) 1996;271(5254):1406-9.
1996: R Sandbrink; Tobias Hartmann; Colin L Masters; Konrad Beyreuther
Genes contributing to Alzheimer's disease.
Molecular psychiatry 1996;1(1):27-40.
1996: M Sarochan; hans förstl; H Sattel; R Zerfass; C Czech; Konrad Beyreuther
Apolipoprotein E genotype does not promote the clinical progression of manifest Alzheimer's disease.
Dementia (Basel, Switzerland) 1996;7(2):120.
1996: P Thilmann; C Ernst; C Czech; S Kaumeier; Konrad Beyreuther; hans förstl
Low apolipoprotein E4 allelic frequency in Alzheimer's disease and functional psychiatric disorders.
Dementia (Basel, Switzerland) 1996;7(2):118-9.
1996: M Simons; Bart De Strooper; Gerd Multhaup; P J Tienari; Carlos G Dotti; Konrad Beyreuther
Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(3):899-908.
1996: Konrad Beyreuther; Gerd Multhaup; U Mönning; R Sandbrink; Dirk Beher; L Hesse; David Small; Colin L Masters
Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines.
Annals of the New York Academy of Sciences 1996;777():74-6.
1996: David Small; T Williamson; G Reed; Heidi J Clarris; Konrad Beyreuther; Colin L Masters; V Nurcombe
The role of heparan sulfate proteoglycans in the pathogenesis of Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;777():316-21.
1996: R Sandbrink; Colin L Masters; Konrad Beyreuther
APP gene family. Alternative splicing generates functionally related isoforms.
Annals of the New York Academy of Sciences 1996;777():281-7.
1996: P J Tienari; Bart De Strooper; E Ikonen; N Ida; M Simons; Colin L Masters; Carlos G Dotti; Konrad Beyreuther
Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease.
Cold Spring Harbor symposia on quantitative biology 1996;61():575-85.
1996: Konrad Beyreuther; Gerd Multhaup; Colin L Masters
Alzheimer's disease: genesis of amyloid.
Ciba Foundation symposium 1996;199():119-27; discussion 127-31.
1995: R N LePage; Amanda J Fosang; S J Fuller; G Murphy; Geneviève Evin; Konrad Beyreuther; Colin L Masters; David Small
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.
FEBS letters 1995;377(2):267-70.
1995: T G Williamson; V Nurcombe; Konrad Beyreuther; Colin L Masters; David Small
Affinity purification of proteoglycans that bind to the amyloid protein precursor of Alzheimer's disease.
Journal of neurochemistry 1995;65(5):2201-8.
1995: Geneviève Evin; Roberto Cappai; Qiao-Xin Li; Janetta G Culvenor; David Small; Konrad Beyreuther; Colin L Masters
Candidate gamma-secretases in the generation of the carboxyl terminus of the Alzheimer's disease beta A4 amyloid: possible involvement of cathepsin D.
Biochemistry 1995;34(43):14185-92.
1995: Bart De Strooper; M Simons; Gerd Multhaup; Fred Van Leuven; Konrad Beyreuther; Carlos G Dotti
Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence.
The EMBO journal 1995;14(20):4932-8.
1995: Heinrich Sticht; P Bayer; Dieter Willbold; S Dames; C Hilbich; Konrad Beyreuther; R W Frank; Paul Rösch
Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease.
European journal of biochemistry / FEBS 1995;233(1):293-8.
1995: Janetta G Culvenor; Anna Friedhuber; S J Fuller; Konrad Beyreuther; Colin L Masters
Expression of the amyloid precursor protein of Alzheimer's disease on the surface of transfected HeLa cells.
Experimental cell research 1995;220(2):474-81.
1995: Heidi J Clarris; Brian Key; Konrad Beyreuther; Colin L Masters; David Small
Expression of the amyloid protein precursor of Alzheimer's disease in the developing rat olfactory system.
Brain research. Developmental brain research 1995;88(1):87-95.
1995: M Simons; P J Tienari; Carlos G Dotti; Konrad Beyreuther
Two-dimensional gel mapping of the processing of the human amyloid precursor protein in rat hippocampal neurons.
FEBS letters 1995;368(2):363-6.
1995: S J Fuller; E Storey; Qiao-Xin Li; A I Smith; Konrad Beyreuther; Colin L Masters
Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein.
Biochemistry 1995;34(25):8091-8.
1995: A Meyer-Franke; mike tropak; J C Roder; P Fischer; Konrad Beyreuther; Rainer Probstmeier; Melitta Schachner
Functional topography of myelin-associated glycoprotein. II. Mapping of domains on molecular fragments.
Journal of neuroscience research 1995;41(3):311-23.
1995: Qiao-Xin Li; Geneviève Evin; David Small; Gerd Multhaup; Konrad Beyreuther; Colin L Masters
Proteolytic processing of Alzheimer's disease beta A4 amyloid precursor protein in human platelets.
The Journal of biological chemistry 1995;270(23):14140-7.
1995: Anne Eckert; hans förstl; H Hartmann; C Czech; U Mönning; Konrad Beyreuther; W E Müller
The amplifying effect of beta-amyloid on cellular calcium signalling is reduced in Alzheimer's disease.
Neuroreport 1995;6(8):1199-202.
1995: M Simons; E Ikonen; P J Tienari; A Cid-Arregui; U Mönning; Konrad Beyreuther; Carlos G Dotti
Intracellular routing of human amyloid protein precursor: axonal delivery followed by transport to the dendrites.
Journal of neuroscience research 1995;41(1):121-8.
1995: S S Zhan; R Sandbrink; Konrad Beyreuther; H P Schmitt
APP with Kunitz type protease inhibitor domain (KPI) correlates with neuritic plaque density but not with cortical synaptophysin immunoreactivity in Alzheimer's disease and non-demented aged subjects: a multifactorial analysis.
Clinical neuropathology 1995;14(3):142-9.
1995: U Mönning; R Sandbrink; Andreas Weidemann; R B Banati; Colin L Masters; Konrad Beyreuther
Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells.
The Journal of biological chemistry 1995;270(13):7104-10.
1995: Geneviève Evin; Konrad Beyreuther; Colin L Masters
A synthetic substrate assay for the gamma-secretase of the beta-A4 amyloid of Alzheimer's disease.
Journal of peptide science : an official publication of the European Peptide Society 1995;1(2):132-9.
1995: Colin L Masters; Konrad Beyreuther
Molecular neuropathology of Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):410-2.
1995: hans förstl; F Hentschel; H Sattel; C Geiger-Kabisch; C Besthorn; C Czech; U Mönning; Konrad Beyreuther
Age-associated memory impairment and early Alzheimer's disease. Only time will tell the difference.
Arzneimittel-Forschung 1995;45(3A):394-7.
1995: Konrad Beyreuther; Colin L Masters
Neurodegeneration and dementia. Alzheimer's disease as a model.
Arzneimittel-Forschung 1995;45(3A):347-50.
1995: J Beer; Colin L Masters; Konrad Beyreuther
Cells from peripheral tissues that exhibit high APP expression are characterized by their high membrane fusion activity.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(1):51-9.
1995: B Urmoneit; C Reinsch; J Turner; C Czech; Konrad Beyreuther; T Dyrks
Inhibition of beta A4 production by specific modulation of beta-secretase activity.
Journal of molecular neuroscience : MN 1995;6(1):23-32.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
APP gene family: unique age-associated changes in splicing of Alzheimer's betaA4-amyloid protein precursor.
Neurobiology of disease 1994;1(1-2):13-24.
1994: hans förstl; C Czech; H Sattel; C Geiger-Kabisch; C Besthorn; Spencer Kreger; U Mönning; Tobias Hartmann; Colin L Masters; Konrad Beyreuther
[Apolipoprotein E and Alzheimer dementia. Personal results and brief literature review].
Der Nervenarzt 1994;65(11):780-6.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
Complete nucleotide and deduced amino acid sequence of rat amyloid protein precursor-like protein 2 (APLP2/APPH): two amino acids length difference to human and murine homologues.
Biochimica et biophysica acta 1994;1219(1):167-70.
1994: Ashley I Bush; Warren H Pettingell; Gerd Multhaup; M d Paradis; J P Vonsattel; James Gusella; Konrad Beyreuther; Colin L Masters; Rudolph E Tanzi
Rapid induction of Alzheimer A beta amyloid formation by zinc.
Science (New York, N.Y.) 1994;265(5177):1464-7.
1994: Konrad Beyreuther; Colin L Masters
Neurobiology. Catching the culprit prion.
Nature 1994;370(6489):419-20.
1994: T Dyrks; U Mönning; Konrad Beyreuther; J Turner
Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive.
FEBS letters 1994;349(2):210-4.
1994: Qiao-Xin Li; M C Berndt; Ashley I Bush; B Rumble; I Mackenzie; Anna Friedhuber; Konrad Beyreuther; Colin L Masters
Membrane-associated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: surface expression on the activated human platelet.
Blood 1994;84(1):133-42.
1994: Heidi J Clarris; V Nurcombe; David Small; Konrad Beyreuther; Colin L Masters
Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.
Journal of neuroscience research 1994;38(3):248-58.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins.
The Journal of biological chemistry 1994;269(19):14227-34.
1994: U Mönning; R Sandbrink; R B Banati; Colin L Masters; Konrad Beyreuther
Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells.
FEBS letters 1994;342(3):267-72.
1994: David Small; V Nurcombe; G Reed; Heidi J Clarris; Robert D. Moir; Konrad Beyreuther; Colin L Masters
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(4):2117-27.
1994: R B Banati; J Gehrmann; U Mönning; C Czech; Konrad Beyreuther; Georg W Kreutzberg
Amyloid precursor protein (APP) as a microglial acute phase protein.
Neuropathology and applied neurobiology 1994;20(2):194-5.
1994: Colin L Masters; Konrad Beyreuther
Alzheimer's disease: a clearer definition of the genetic components.
The Medical journal of Australia 1994;160(5):243-4.
1994: S S Zhan; Konrad Beyreuther; H P Schmitt
Synaptophysin immunoreactivity of the cortical neuropil in vascular dementia of Binswanger type compared with the dementia of Alzheimer type and nondemented controls.
Dementia (Basel, Switzerland) 1994;5(2):79-87.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
Beta A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons.
The Journal of biological chemistry 1994;269(2):1510-7.
1994: C Czech; hans förstl; F Hentschel; U Mönning; C Besthorn; C Geiger-Kabisch; H Sattel; Colin L Masters; Konrad Beyreuther
Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease: prevalence, plasma cholesterol levels and cerebrovascular change.
European archives of psychiatry and clinical neuroscience 1994;243(5):291-2.
1994: B O Osuntokun; A Ogunniyi; Effiong Akang; PU Aghadiuno; A Ilori; E A Bamgboye; Konrad Beyreuther; Colin L Masters
Beta A4-amyloid in the brains of non-demented Nigerian Africans.
Lancet 1994;343(8888):56.
1994: C Czech; Colin L Masters; Konrad Beyreuther
Alzheimer's disease and transgenic mice.
Journal of neural transmission. Supplementum 1994;44():219-30.
1993: C Hilbich; U Mönning; C Grund; Colin L Masters; Konrad Beyreuther
Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11.
The Journal of biological chemistry 1993;268(35):26571-7.
1993: Anna Seelig; Gerd Multhaup; B Pesold-Hurt; Konrad Beyreuther; Peter-M Kloetzel
Drosophila proteasome Dm25 subunit substitutes the mouse MC3 subunit in hybrid proteasomes. The N-terminal domain is essential for subunit incorporation.
The Journal of biological chemistry 1993;268(34):25561-7.
1993: W Schubert; Colin L Masters; Konrad Beyreuther
APP+ T lymphocytes selectively sorted to endomysial tubes in polymyositis displace NCAM-expressing muscle fibers.
European journal of cell biology 1993;62(2):333-42.
1993: T Dyrks; E Dyrks; U Mönning; B Urmoneit; J Turner; Konrad Beyreuther
Generation of beta A4 from the amyloid protein precursor and fragments thereof.
FEBS letters 1993;335(1):89-93.
1993: C Czech; V Mönning; P J Tienari; Tobias Hartmann; Colin L Masters; Konrad Beyreuther; hans förstl
Apolipoprotein E-epsilon 4 allele and Alzheimer's disease.
Lancet 1993;342(8882):1309.
1993: M Dichgans; U Mönning; G König; R Sandbrink; Colin L Masters; Konrad Beyreuther
APP expression in primary neuronal cell cultures from P6 mice during in vitro differentiation.
Dementia (Basel, Switzerland) 1993;4(6):301-7.
1993: R B Banati; J Gehrmann; C Czech; U Mönning; Leonard L Jones; G König; Konrad Beyreuther; Georg W Kreutzberg
Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia.
Glia 1993;9(3):199-210.
1993: Konrad Beyreuther; P Pollwein; Gerd Multhaup; U Mönning; G König; T Dyrks; W Schubert; Colin L Masters
Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome.
Annals of the New York Academy of Sciences 1993;695():91-102.
1993: R Sandbrink; R Banati; Colin L Masters; Konrad Beyreuther; G König
Expression of L-APP mRNA in brain cells.
Annals of the New York Academy of Sciences 1993;695():183-9.
1993: Ashley I Bush; Konrad Beyreuther; Colin L Masters
The beta A4 amyloid protein precursor in human circulation.
Annals of the New York Academy of Sciences 1993;695():175-82.
1993: David Small; V Nurcombe; Heidi J Clarris; Konrad Beyreuther; Colin L Masters
The role of extracellular matrix in the processing of the amyloid protein precursor of Alzheimer's disease.
Annals of the New York Academy of Sciences 1993;695():169-74.
1993: Ashley I Bush; Gerd Multhaup; Robert D. Moir; T G Williamson; David Small; B Rumble; P Pollwein; Konrad Beyreuther; Colin L Masters
A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease.
The Journal of biological chemistry 1993;268(22):16109-12.
1993: T Dyrks; E Dyrks; Colin L Masters; Konrad Beyreuther
Amyloidogenicity of rodent and human beta A4 sequences.
FEBS letters 1993;324(2):231-6.
1993: S S Zhan; Konrad Beyreuther; H P Schmitt
Quantitative assessment of the synaptophysin immuno-reactivity of the cortical neuropil in various neurodegenerative disorders with dementia.
Dementia (Basel, Switzerland) 1993;4(2):66-74.
1993: Gerd Multhaup; Colin L Masters; Konrad Beyreuther
A molecular approach to Alzheimer's disease.
Biological chemistry Hoppe-Seyler 1993;374(1):1-8.
1993: DON GUIROY; M Mellini; M Miyazaki; C Hilbich; J Safar; R M Garruto; R Yanagihara; Konrad Beyreuther; D Carleton Gajdusek
Neurofibrillary tangles of Guamanian amyotrophic lateral sclerosis, parkinsonism-dementia and neurologically normal Guamanians contain a 4- to 4.5-kilodalton protein which is immunoreactive to anti-amyloid beta/A4-protein antibodies.
Acta neuropathologica 1993;86(3):265-74.
1993: S S Zhan; Konrad Beyreuther; H P Schmitt
Vascular dementia in Spatz-Lindenberg's disease (SLD): cortical synaptophysin immunoreactivity as compared with dementia of Alzheimer type and non-demented controls.
Acta neuropathologica 1993;86(3):259-64.
1993: Marla Gearing; R W Wilson; Elizabeth R Unger; Earl R Shelton; H W Chan; Colin L Masters; Konrad Beyreuther; Suzanne S Mirra
Amyloid precursor protein (APP) in the striatum in Alzheimer's disease: an immunohistochemical study.
Journal of neuropathology and experimental neurology 1993;52(1):22-30.
1992: U Mönning; G König; R B Banati; H Mechler; C Czech; J Gehrmann; U Schreiter-Gasser; Colin L Masters; Konrad Beyreuther
Alzheimer beta A4-amyloid protein precursor in immunocompetent cells.
The Journal of biological chemistry 1992;267(33):23950-6.
1992: C Hilbich; B Kisters-Woike; J Reed; Colin L Masters; Konrad Beyreuther
Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides.
Journal of molecular biology 1992;228(2):460-73.
1992: G Woehlke; E Laussermair; E Schwarz; D Oesterhelt; H Reinke; Konrad Beyreuther; Peter Dimroth
Appendix. Sequence of the beta-subunit of oxaloacetate decarboxylase from Klebsiella pneumoniae: a correction of the C-terminal part.
The Journal of biological chemistry 1992;267(32):22804-5.
1992: David Small; V Nurcombe; Robert D. Moir; S Michaelson; D Monard; Konrad Beyreuther; Colin L Masters
Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(11):4143-50.
1992: Robert D. Moir; Ralph N Martins; Ashley I Bush; David Small; E A Milward; B A Rumble; Gerd Multhaup; Konrad Beyreuther; Colin L Masters
Human brain beta A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization.
Journal of neurochemistry 1992;59(4):1490-8.
1992: T Dyrks; E Dyrks; Tobias Hartmann; Colin L Masters; Konrad Beyreuther
Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation.
The Journal of biological chemistry 1992;267(25):18210-7.
1992: S S Zhan; Konrad Beyreuther; H P Schmitt
Neuronal ubiquitin and neurofilament expression in different lysosomal storage disorders.
Clinical neuropathology 1992;11(5):251-5.
1992: T Dyrks; E Dyrks; Colin L Masters; Konrad Beyreuther
Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate.
FEBS letters 1992;309(1):20-4.
1992: E A Milward; R Papadopoulos; S J Fuller; Robert D. Moir; D Small; Konrad Beyreuther; Colin L Masters
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.
Neuron 1992;9(1):129-37.
1992: P Prior; B Schmitt; G Grenningloh; I Pribilla; Gerd Multhaup; Konrad Beyreuther; Y Maulet; P Werner; D Langosch; Joachim Kirsch
Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein.
Neuron 1992;8(6):1161-70.
1992: G König; U Mönning; C Czech; R Prior; R Banati; U Schreiter-Gasser; J Bauer; Colin L Masters; Konrad Beyreuther
Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells.
The Journal of biological chemistry 1992;267(15):10804-9.
1992: J M Candy; F K McArthur; A E Oakley; G A Taylor; C P Chen; S A Mountfort; J E Thompson; P R Chalker; H E Bishop; Konrad Beyreuther
Aluminium accumulation in relation to senile plaque and neurofibrillary tangle formation in the brains of patients with renal failure.
Journal of the neurological sciences 1992;107(2):210-8.
1992: Hilkka Soininen; Stina Syrjänen; Outi Kopra; H Neittaanmäki; Riitta Miettinen; Leo Paljärvi; Kari Syrjänen; Konrad Beyreuther; PJ Riekkinen
Amyloid beta-protein deposition in skin of patients with dementia.
Lancet 1992;339(8787):245.
1992: P Pollwein; Colin L Masters; Konrad Beyreuther
The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter.
Nucleic acids research 1992;20(1):63-8.
1992: Konrad Beyreuther; T Dyrks; C Hilbich; U Mönning; G König; Gerd Multhaup; P Pollwein; Colin L Masters
Amyloid precursor protein (APP) and beta A4 amyloid in Alzheimer's disease and Down syndrome.
Progress in clinical and biological research 1992;379():159-82.
1992: Ashley I Bush; Konrad Beyreuther; Colin L Masters
Beta A4 amyloid protein and its precursor in Alzheimer's disease.
Pharmacology & therapeutics 1992;56(1):97-117.
1991: F Yamaguchi; S J Richards; Konrad Beyreuther; M Salbaum; G A Carlson; Stephen B Dunnett
Transgenic mice for the amyloid precursor protein 695 isoform have impaired spatial memory.
Neuroreport 1991;2(12):781-4.
1991: T Ohgami; Tetsuyuki Kitamoto; A Weidmann; Konrad Beyreuther; Jun Tateishi
Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease.
The American journal of pathology 1991;139(6):1245-50.
1991: David Small; Robert D. Moir; S J Fuller; S Michaelson; Ashley I Bush; Qiao-Xin Li; E Milward; C Hilbich; A Weidemann; Konrad Beyreuther
A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease.
Biochemistry 1991;30(44):10795-9.
1991: W Schubert; R Prior; Andreas Weidemann; Heinrich Dircksen; Gerd Multhaup; Colin L Masters; Konrad Beyreuther
Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.
Brain research 1991;563(1-2):184-94.
1991: C Hilbich; B Kisters-Woike; J Reed; Colin L Masters; Konrad Beyreuther
Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4.
European journal of biochemistry / FEBS 1991;201(1):61-9.
1991: W Dahr; G Knuppertz; Konrad Beyreuther; J J Moulds; Marilyn K Moulds; S Wilkinson; Calliope Capon; B Fournet; PD Issitt
Studies on the structures of the Tm, Sj, M1, Can, Sext and Hu blood group antigens.
Biological chemistry Hoppe-Seyler 1991;372(8):573-84.
1991: Konrad Beyreuther; Colin L Masters
Amyloid precursor protein (APP) and beta A4 amyloid in the etiology of Alzheimer's disease: precursor-product relationships in the derangement of neuronal function.
Brain pathology (Zurich, Switzerland) 1991;1(4):241-51.
1991: Colin L Masters; Konrad Beyreuther
Alzheimer's disease: molecular basis of structural lesions.
Brain pathology (Zurich, Switzerland) 1991;1(4):226-7.
1991: U Ganter; S Strauss; U Jonas; Andreas Weidemann; Konrad Beyreuther; B Volk; M Berger; J Bauer
Alpha 2-macroglobulin synthesis in interleukin-6-stimulated human neuronal (SH-SY5Y neuroblastoma) cells. Potential significance for the processing of Alzheimer beta-amyloid precursor protein.
FEBS letters 1991;282(1):127-31.
1991: Tetsuyuki Kitamoto; T Muramoto; C Hilbich; Konrad Beyreuther; Jun Tateishi
N-terminal sequence of prion protein is also integrated into kuru plaques in patients with Gerstmann-Sträussler syndrome.
Brain research 1991;545(1-2):319-21.
1991: P Le Coz; Jacqueline Mikol; J Ferrand; France Woimant; Colin L Masters; Konrad Beyreuther; M Haguenau; J Cophignon; B Pepin
Granulomatous angiitis and cerebral amyloid angiopathy presenting as a mass lesion.
Neuropathology and applied neurobiology 1991;17(2):149-55.
1991: R Prior; U Mönning; U Schreiter-Gasser; Andreas Weidemann; Kaj Blennow; Carl-Gerhard Gottfries; Colin L Masters; Konrad Beyreuther
Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid.
Neuroscience letters 1991;124(1):69-73.
1991: C Hilbich; B Kisters-Woike; J Reed; Colin L Masters; Konrad Beyreuther
Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease.
Journal of molecular biology 1991;218(1):149-63.
1991: Lee J Martin; Sangram S Sisodia; Edward H Koo; L C Cork; T L Dellovade; Andreas Weidemann; Konrad Beyreuther; Colin L Masters; Donald L Price
Amyloid precursor protein in aged nonhuman primates.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1461-5.
1991: S J Richards; J J Waters; Konrad Beyreuther; Colin L Masters; C M Wischik; Dennis Sparkman; Charles L White; Carmela Abraham; Stephen B Dunnett
Transplants of mouse trisomy 16 hippocampus provide a model of Alzheimer's disease neuropathology.
The EMBO journal 1991;10(2):297-303.
1991: G König; J M Salbaum; O Wiestler; W Lang; H P Schmitt; Colin L Masters; Konrad Beyreuther
Alternative splicing of the beta A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients.
Brain research. Molecular brain research 1991;9(3):259-62.
1991: Jean-Jacques Martin; J Gheuens; M Bruyland; Patrick Cras; Antoon Vandenberghe; Colin L Masters; Konrad Beyreuther; R Dom; Chantal Ceuterick; Ursula Lübke
Early-onset Alzheimer's disease in 2 large Belgian families.
Neurology 1991;41(1):62-8.
1991: Ralph N Martins; P J Robinson; J O Chleboun; Konrad Beyreuther; Colin L Masters
The molecular pathology of amyloid deposition in Alzheimer's disease.
Molecular neurobiology 1991;5(2-4):389-98.
1991: Konrad Beyreuther
[First steps against Alzheimer's].
Zahntechnik (Zurich, Switzerland) 1991;48(5):408-11.
1991: Konrad Beyreuther; Ashley I Bush; T Dyrks; C Hilbich; G König; U Mönning; Gerd Multhaup; R Prior; B Rumble; W Schubert
Mechanisms of amyloid deposition in Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;640():129-39.
1991: D Carleton Gajdusek; Konrad Beyreuther; P Brown; L C Cork; D D Cunningham; Blas Frangione; C J Gibbs; Lev G Goldfarb; Dmitry Goldgaber; Karen K. Hsiao Ashe
Regulation and genetic control of brain amyloid. FESN Study Group.
Brain research. Brain research reviews 1991;16(1):83-114.
1990: U Mönning; G König; R Prior; H Mechler; U Schreiter-Gasser; Colin L Masters; Konrad Beyreuther
Synthesis and secretion of Alzheimer amyloid beta A4 precursor protein by stimulated human peripheral blood leucocytes.
FEBS letters 1990;277(1-2):261-6.
1990: L C Cork; Colin L Masters; Konrad Beyreuther; Donald L Price
Development of senile plaques. Relationships of neuronal abnormalities and amyloid deposits.
The American journal of pathology 1990;137(6):1383-92.
1990: K Sorimachi; David J Craik; E J Lloyd; Konrad Beyreuther; Colin L Masters
Identification of a beta-turn in the tertiary structure of a peptide fragment of the Alzheimer amyloid protein.
Biochemistry international 1990;22(3):447-54.
1990: G König; Colin L Masters; Konrad Beyreuther
Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern.
FEBS letters 1990;269(2):305-10.
1990: P Delaère; Charles Duyckaerts; Colin L Masters; Konrad Beyreuther; F Piette; JEAN-JACQUES HAUW
Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person.
Neuroscience letters 1990;116(1-2):87-93.
1990: Pari Malherbe; A Draguhn; Gerd Multhaup; Konrad Beyreuther; H Möhler
GABAA-receptor expressed from rat brain alpha- and beta-subunit cDNAs displays potentiation by benzodiazepine receptor ligands.
Brain research. Molecular brain research 1990;8(3):199-208.
1990: N Catteruccia; J Willingale-Theune; D Bunke; R Prior; Colin L Masters; A Crisanti; Konrad Beyreuther
Ultrastructural localization of the putative precursors of the A4 amyloid protein associated with Alzheimer's disease.
The American journal of pathology 1990;137(1):19-26.
1990: Christian Haass; B Pesold-Hurt; Gerd Multhaup; Konrad Beyreuther; Peter-M Kloetzel
The Drosophila PROS-28.1 gene is a member of the proteasome gene family.
Gene 1990;90(2):235-41.
1990: J L Van den Brande; Cok M Hoogerbrugge; Konrad Beyreuther; P Roepstorff; J Jansen; Sylvia C van Buul-Offers
Isolation and partial characterization of IGF-like peptides from Cohn fraction IV of human plasma.
Acta endocrinologica 1990;122(6):683-95.
1990: G Grenningloh; I Pribilla; P Prior; Gerd Multhaup; Konrad Beyreuther; O Taleb; Heinrich Betz
Cloning and expression of the 58 kd beta subunit of the inhibitory glycine receptor.
Neuron 1990;4(6):963-70.
1990: R A Rupp; U Kruse; Gerd Multhaup; U Göbel; Konrad Beyreuther; Albrecht Sippel
Chicken NFI/TGGCA proteins are encoded by at least three independent genes: NFI-A, NFI-B and NFI-C with homologues in mammalian genomes.
Nucleic acids research 1990;18(9):2607-16.
1990: W Dahr; D Blanchard; C Chevalier; J P Cartron; Konrad Beyreuther; B Fournet
The Mz variety of the St(a+) phenotype--a variant of glycophorin A exhibiting a deletion.
Biological chemistry Hoppe-Seyler 1990;371(5):403-10.
1990: Sangram S Sisodia; Edward H Koo; Konrad Beyreuther; A Unterbeck; Donald L Price
Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.
Science (New York, N.Y.) 1990;248(4954):492-5.
1990: Wilfred Goldmann; Nora Hunter; James D Foster; J M Salbaum; Konrad Beyreuther; James Hope
Two alleles of a neural protein gene linked to scrapie in sheep.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2476-80.
1990: Edward H Koo; Sangram S Sisodia; D R Archer; Lee J Martin; Andreas Weidemann; Konrad Beyreuther; P Fischer; Colin L Masters; Donald L Price
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1561-5.
1990: Lary Walker; Colin L Masters; Konrad Beyreuther; Donald L Price
Amyloid in the brains of aged squirrel monkeys.
Acta neuropathologica 1990;80(4):381-7.
1990: S J Richards; J J Waters; D C Rogers; F L Martel; Dennis Sparkman; Charles L White; Konrad Beyreuther; Colin L Masters; Stephen B Dunnett
Hippocampal grafts derived from embryonic trisomy 16 mice exhibit amyloid (A4) and neurofibrillary pathology.
Progress in brain research 1990;82():215-23.
1990: Konrad Beyreuther; Colin L Masters
Nomenclature of amyloid A4 proteins and their precursors in Alzheimer's disease and Down's syndrome.
Neurobiology of aging 1990;11(1):66-8.
1990: Colin L Masters; Konrad Beyreuther
Protein abnormalities in neurofibrillary tangles: their relation to the extracellular amyloid deposits of the A4 protein in Alzheimer's disease.
Advances in neurology 1990;51():151-61.
1989: J M Rozemuller; Piet Eikelenboom; F C Stam; Konrad Beyreuther; Colin L Masters
A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition.
Journal of neuropathology and experimental neurology 1989;48(6):674-91.
1989: Bernardino Ghetti; Fabrizio Tagliavini; Colin L Masters; Konrad Beyreuther; Giorgio Giaccone; L Verga; Martin R Farlow; P M Conneally; Stephen R Dlouhy; Biagio Azzarelli
Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family.
Neurology 1989;39(11):1453-61.
1989: E Laussermair; E Schwarz; D Oesterhelt; H Reinke; Konrad Beyreuther; Peter Dimroth
The sodium ion translocating oxaloacetate decarboxylase of Klebsiella pneumoniae. Sequence of the integral membrane-bound subunits beta and gamma.
The Journal of biological chemistry 1989;264(25):14710-5.
1989: B el-Maliki; D Blanchard; W Dahr; Konrad Beyreuther; Jean-Pierre Cartron
Structural homology between glycophorins C and D of human erythrocytes.
European journal of biochemistry / FEBS 1989;183(3):639-43.
1989: W Dahr; V Vengelen-Tyler; E Dybkjaer; Konrad Beyreuther
Structural analysis of glycophorin A from Miltenberger class VIII erythrocytes.
Biological chemistry Hoppe-Seyler 1989;370(8):855-9.
1989: Christian Haass; B Pesold-Hurt; Gerd Multhaup; Konrad Beyreuther; Peter-M Kloetzel
The PROS-35 gene encodes the 35 kd protein subunit of Drosophila melanogaster proteasome.
The EMBO journal 1989;8(8):2373-9.
1989: Bradley T Hyman; Gary W Van Hoesen; Konrad Beyreuther; Colin L Masters
A4 amyloid protein immunoreactivity is present in Alzheimer's disease neurofibrillary tangles.
Neuroscience letters 1989;101(3):352-5.
1989: David Nochlin; Shuzo M Sumi; Thomas D Bird; AD Snow; C M Leventhal; Konrad Beyreuther; Colin L Masters
Familial dementia with PrP-positive amyloid plaques: a variant of Gerstmann-Sträussler syndrome.
Neurology 1989;39(7):910-8.
1989: B Rumble; R Retallack; C Hilbich; G Simms; Gerd Multhaup; Ralph N Martins; A Hockey; P Montgomery; Konrad Beyreuther; Colin L Masters
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.
The New England journal of medicine 1989;320(22):1446-52.
1989: W Dahr; P M Pilkington; H Reinke; D Blanchard; Konrad Beyreuther
A novel variety of the Dantu gene complex (DantuMD) detected in a Caucasian.
Blut 1989;58(5):247-53.
1989: Andreas Weidemann; G König; D Bunke; P Fischer; J M Salbaum; Colin L Masters; Konrad Beyreuther
Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.
Cell 1989;57(1):115-26.
1989: H G Lemaire; J M Salbaum; Gerd Multhaup; J Kang; R M Bayney; A Unterbeck; Konrad Beyreuther; Benno Müller-Hill
The PreA4(695) precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons.
Nucleic acids research 1989;17(2):517-22.
1989: F L Mastaglia; Colin L Masters; Konrad Beyreuther; B A Kakulas
Deposition of Alzheimer's disease amyloid (A4) protein in the cerebral cortex in Parkinson's disease.
Progress in clinical and biological research 1989;317():475-84.
1989: J M Salbaum; Andreas Weidemann; Colin L Masters; Konrad Beyreuther
The promoter of Alzheimer's disease amyloid A4 precursor gene.
Progress in clinical and biological research 1989;317():277-83.
1989: B Müller-Hill; Konrad Beyreuther
Molecular biology of Alzheimer's disease.
Annual review of biochemistry 1989;58():287-307.
1989: T Dyrks; G König; C Hilbich; Colin L Masters; Konrad Beyreuther
Molecular pathology of the amyloid A4 precursor of Alzheimer's disease.
Progress in clinical and biological research 1989;317():877-91.
1989: G König; Konrad Beyreuther; Colin L Masters; H P Schmitt; J M Salbaum
PreA4 mRNA distribution in brain areas.
Progress in clinical and biological research 1989;317():1027-36.
1989: Colin L Masters; Konrad Beyreuther
The pathology of the amyloid A4 precursor of Alzheimer's disease.
Annals of medicine 1989;21(2):89-90.
1988: James Hope; L J Reekie; Nora Hunter; Gerd Multhaup; Konrad Beyreuther; H White; A C Scott; Mick J Stack; Michael Dawson; Gerald A H Wells
Fibrils from brains of cows with new cattle disease contain scrapie-associated protein.
Nature 1988;336(6197):390-2.
1988: S Münch; U Ljungberg; J Steppuhn; A Schneiderbauer; R Nechushtai; Konrad Beyreuther; Reinhold G Herrmann
Nucleotide sequences of cDNAs encoding the entire precursor polypeptides for subunits II and III of the photosystem I reaction center from spinach.
Current genetics 1988;14(5):511-8.
1988: L Davies; B Wolska; C Hilbich; Gerd Multhaup; Ralph N Martins; G Simms; Konrad Beyreuther; Colin L Masters
A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques.
Neurology 1988;38(11):1688-93.
1988: Toni M Kutchan; N Hampp; F Lottspeich; Konrad Beyreuther; Meinhart H Zenk
The cDNA clone for strictosidine synthase from Rauvolfia serpentina. DNA sequence determination and expression in Escherichia coli.
FEBS letters 1988;237(1-2):40-4.
1988: J M Salbaum; Andreas Weidemann; H G Lemaire; Colin L Masters; Konrad Beyreuther
The promoter of Alzheimer's disease amyloid A4 precursor gene.
The EMBO journal 1988;7(9):2807-13.
1988: C Bloy; D Blanchard; W Dahr; Konrad Beyreuther; C Salmon; J P Cartron
Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.
Blood 1988;72(2):661-6.
1988: A Lautner; R Klein; U Ljungberg; H Reiländer; D Bartling; Bertil Andersson; H Reinke; Konrad Beyreuther; Reinhold G Herrmann
Nucleotide sequence of cDNA clones encoding the complete precursor for the "10-kDa" polypeptide of photosystem II from spinach.
The Journal of biological chemistry 1988;263(21):10077-81.
1988: E Schwarz; D Oesterhelt; H Reinke; Konrad Beyreuther; Peter Dimroth
The sodium ion translocating oxalacetate decarboxylase of Klebsiella pneumoniae. Sequence of the biotin-containing alpha-subunit and relationship to other biotin-containing enzymes.
The Journal of biological chemistry 1988;263(20):9640-5.
1988: G Gäde; C Hilbich; Konrad Beyreuther; K L Rinehart
Sequence analyses of two neuropeptides of the AKH/RPCH-family from the lubber grasshopper, Romalea microptera.
Peptides 1988;9(4):681-8.
1988: Andrea Crisanti; H M Müller; C Hilbich; F Sinigaglia; Hugues Matile; M McKay; J Scaife; Konrad Beyreuther; Hermann Bujard
Epitopes recognized by human T cells map within the conserved part of the GP190 of P. falciparum.
Science (New York, N.Y.) 1988;240(4857):1324-6.
1988: B D Shivers; C Hilbich; Gerd Multhaup; M Salbaum; Konrad Beyreuther; P H Seeburg
Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact.
The EMBO journal 1988;7(5):1365-70.
1988: B Surek; B Pillay; U Rdest; Konrad Beyreuther; Werner Goebel
Evidence for two different gas vesicle proteins and genes in Halobacterium halobium.
Journal of bacteriology 1988;170(4):1746-51.
1988: T Dyrks; Andreas Weidemann; Gerd Multhaup; J M Salbaum; H G Lemaire; J Kang; Benno Müller-Hill; Colin L Masters; Konrad Beyreuther
Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease.
The EMBO journal 1988;7(4):949-57.
1988: James Hope; Gerd Multhaup; L J Reekie; R H Kimberlin; Konrad Beyreuther
Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie.
European journal of biochemistry / FEBS 1988;172(2):271-7.
1988: Colin L Masters; Konrad Beyreuther
The blood-brain barrier in Alzheimer's disease and normal aging.
Neurobiology of aging 1988;9(1):43-4.
1988: Georg Herrler; Gerd Multhaup; Konrad Beyreuther; Hans-Dieter Klenk
Serine 71 of the glycoprotein HEF is located at the active site of the acetylesterase of influenza C virus.
Archives of virology 1988;102(3-4):269-74.
1988: Colin L Masters; Konrad Beyreuther
Neuropathology of unconventional virus infections: molecular pathology of spongiform change and amyloid plaque deposition.
Ciba Foundation symposium 1988;135():24-36.
1988: G Grenningloh; A Rienitz; B Schmitt; C Methfessel; M Zensen; Konrad Beyreuther; Eckart D Gundelfinger; Heinrich Betz
Molecular cloning of the antagonist-binding subunit of the glycine receptor.
Journal of receptor research 1988;8(1-4):183-93.
1987: D Blanchard; W Dahr; Konrad Beyreuther; J Moulds; J P Cartron
Hybrid glycophorins from human erythrocyte membranes. Isolation and complete structural analysis of the novel sialoglycoprotein from St(a+) red cells.
European journal of biochemistry / FEBS 1987;167(2):361-6.
1987: Edgar Schmitt; B Fassbender; Konrad Beyreuther; E Spaeth; R Schwarzkopf; E Rüde
Characterization of a T cell-derived lymphokine that acts synergistically with IL 3 on the growth of murine mast cells and is identical with IL 4.
Immunobiology 1987;174(4-5):406-19.
1987: G Grenningloh; A Rienitz; B Schmitt; C Methfessel; M Zensen; Konrad Beyreuther; Eckart D Gundelfinger; Heinrich Betz
The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors.
Nature 1987;328(6127):215-20.
1987: W Dahr; Konrad Beyreuther; J Moulds; P Unger
Hybrid glycophorins from human erythrocyte membranes. I. Isolation and complete structural analysis of the hybrid sialoglycoprotein from Dantu-positive red cells of the N.E. variety.
European journal of biochemistry / FEBS 1987;166(1):31-6.
1987: W Dahr; Konrad Beyreuther; J J Moulds
Structural analysis of the major human erythrocyte membrane sialoglycoprotein from Miltenberger class VII cells.
European journal of biochemistry / FEBS 1987;166(1):27-30.
1987: D Blanchard; W Dahr; M Hummel; F Latron; Konrad Beyreuther; J P Cartron
Glycophorins B and C from human erythrocyte membranes. Purification and sequence analysis.
The Journal of biological chemistry 1987;262(12):5808-11.
1987: DON GUIROY; M Miyazaki; Gerd Multhaup; P Fischer; R M Garruto; Konrad Beyreuther; Colin L Masters; G Simms; CJ Gibbs; D Carleton Gajdusek
Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(7):2073-7.
1987: J Kang; H G Lemaire; A Unterbeck; J M Salbaum; Colin L Masters; K H Grzeschik; Gerd Multhaup; Konrad Beyreuther; Benno Müller-Hill
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor.
Nature 1987;325(6106):733-6.
1987: J Pohlner; R Halter; Konrad Beyreuther; Thomas F Meyer
Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease.
Nature 1987;325(6103):458-62.
1987: Colin L Masters; Konrad Beyreuther
Neuronal origin of cerebral amyloidogenic proteins: their role in Alzheimer's disease and unconventional virus diseases of the nervous system.
Ciba Foundation symposium 1987;126():49-64.
1986: Colin L Masters; Konrad Beyreuther
The structure of amyloid filaments in Alzheimer's disease and the unconventional virus infections of the nervous system.
Psychological medicine 1986;16(4):735-7.
1986: Josef Deutscher; B Pevec; Konrad Beyreuther; H H Kiltz; Wolfgang Hengstenberg
Streptococcal phosphoenolpyruvate-sugar phosphotransferase system: amino acid sequence and site of ATP-dependent phosphorylation of HPr.
Biochemistry 1986;25(21):6543-51.
1986: W Dahr; S Wilkinson; P D Issitt; Konrad Beyreuther; M Hummel; P Morel
High frequency antigens of human erythrocyte membrane sialoglycoproteins, III. Studies on the EnaFR, Wrb and Wra antigens.
Biological chemistry Hoppe-Seyler 1986;367(10):1033-45.
1986: J Hope; L J Morton; C F Farquhar; Gerd Multhaup; Konrad Beyreuther; R H Kimberlin
The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP).
The EMBO journal 1986;5(10):2591-7.
1986: Silvano Riva; C Morandi; P Tsoulfas; M Pandolfo; Giuseppe Biamonti; B Merrill; K R Williams; Gerd Multhaup; Konrad Beyreuther; H Werr
Mammalian single-stranded DNA binding protein UP I is derived from the hnRNP core protein A1.
The EMBO journal 1986;5(9):2267-73.
1986: U Schulze-Gahmen; H D Klenk; Konrad Beyreuther
Immunogenicity of loop-structured short synthetic peptides mimicking the antigenic site A of influenza virus hemagglutinin.
European journal of biochemistry / FEBS 1986;159(2):283-9.
1985: W Dahr; Konrad Beyreuther
A revision of the N-terminal structure of sialoglycoprotein D (glycophorin C) from human erythrocyte membranes.
Biological chemistry Hoppe-Seyler 1985;366(11):1067-70.
1985: Colin L Masters; Gerd Multhaup; G Simms; J Pottgiesser; Ralph N Martins; Konrad Beyreuther
Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.
The EMBO journal 1985;4(11):2757-63.
1985: G Mannhaupt; Konrad Beyreuther; Georg Michaelis
Cytochrome b, the var 1 protein, and subunits I and III of cytochrome c oxidase are synthesized without transient presequences in Saccharomyces cerevisiae.
European journal of biochemistry / FEBS 1985;150(3):435-9.
1985: U Schulze-Gahmen; H Prinz; U Glatter; Konrad Beyreuther
Towards assignment of secondary structures by anti-peptide antibodies. Specificity of the immune response to a beta-turn.
The EMBO journal 1985;4(7):1731-7.
1985: Andreas Radbruch; S Zaiss; C Kappen; M Brüggemann; Konrad Beyreuther; K Rajewsky
Drastic change in idiotypic but not antigen-binding specificity of an antibody by a single amino-acid substitution.
Nature 1985;315(6019):506-8.
1985: Colin L Masters; G Simms; N A Weinman; Gerd Multhaup; B L McDonald; Konrad Beyreuther
Amyloid plaque core protein in Alzheimer disease and Down syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(12):4245-9.
1985: Gerd Multhaup; H Diringer; H Hilmert; H Prinz; J Heukeshoven; Konrad Beyreuther
The protein component of scrapie-associated fibrils is a glycosylated low molecular weight protein.
The EMBO journal 1985;4(6):1495-501.
1985: K Stüber; Josef Deutscher; H M Sobek; Wolfgang Hengstenberg; Konrad Beyreuther
Amino acid sequence of the amphiphilic phosphocarrier protein factor IIILac of the lactose-specific phosphotransferase system of Staphylococcus.
Biochemistry 1985;24(5):1164-8.
1985: G Karmann; Konrad Beyreuther; M Cramer; B Holtkamp; S Proksa; K Rajewsky
A structural somatic variant of the Kk antigen is generated by point mutation.
Immunogenetics 1985;22(1):35-48.
1985: B Bieseler; H Prinz; Konrad Beyreuther
Topological studies of lactose permease of Escherichia coli by protein sequence analysis.
Annals of the New York Academy of Sciences 1985;456():309-25.
1984: P Zabel; M Moerman; G Lomonossoff; M Shanks; Konrad Beyreuther
Cowpea mosaic virus VPg: sequencing of radiochemically modified protein allows mapping of the gene on B RNA.
The EMBO journal 1984;3(7):1629-34.
1984: W Dahr; M Kordowicz; W John Judd; J Moulds; Konrad Beyreuther; J Krüger
Structural analysis of the Ss sialoglycoprotein specific for Henshaw blood group from human erythrocyte membranes.
European journal of biochemistry / FEBS 1984;141(1):51-5.
1984: R Dildrop; J Bovens; M Siekevitz; Konrad Beyreuther; Klaus Rajewsky
A V region determinant (idiotope) expressed at high frequency in B lymphocytes is encoded by a large set of antibody structural genes.
The EMBO journal 1984;3(3):517-23.
1984: W Dahr; R A Newman; M Contreras; M Kordowicz; P Teesdale; Konrad Beyreuther; J Krüger
Structures of Miltenberger class I and II specific major human erythrocyte membrane sialoglycoproteins.
European journal of biochemistry / FEBS 1984;138(2):259-65.
1983: S Zaiss; Konrad Beyreuther
Myeloma class switch variant X63.2aRI-16 secretes IgG2a and IgG1 with identical VDJ sequence.
European journal of immunology 1983;13(6):508-13.
1983: F Buck; K D Hahn; W Zemann; Heinz Rüterjans; J R Sadler; Konrad Beyreuther; R Kaptein; R Scheek; W E Hull
NMR study of the interaction between the lac repressor and the lac operator.
European journal of biochemistry / FEBS 1983;132(2):321-7.
1983: R M Scheek; Erik R P Zuiderweg; K J Klappe; J H van Boom; R Kaptein; H Rüterjans; Konrad Beyreuther
lac Repressor headpiece binds specifically to half of the lac operator: a proton nuclear magnetic resonance study.
Biochemistry 1983;22(1):228-35.
1983: E Pratje; G Mannhaupt; Georg Michaelis; Konrad Beyreuther
A nuclear mutation prevents processing of a mitochondrially encoded membrane protein in Saccharomyces cerevisiae.
The EMBO journal 1983;2(7):1049-54.
1983: Konrad Beyreuther; J Bovens; M Brüggemann; R Dildrop; Garnett Kelsoe; U Krawinkel; C Müller; S Nishikawa; Andreas Radbruch; M Reth
Idiotypic determinants used in the analysis of antibody diversification and as regulatory targets.
Annals of the New York Academy of Sciences 1983;418():121-9.
1982: Josef Deutscher; Konrad Beyreuther; H M Sobek; K Stüber; Wolfgang Hengstenberg
Phosphoenolpyruvate-dependent phosphotransferase system of Staphylococcus aureus: factor IIIlac, a trimeric phospho-carrier protein that also acts as a phase transfer catalyst.
Biochemistry 1982;21(20):4867-73.
1982: W Dahr; Konrad Beyreuther; M Kordowicz; J Krüger
N-terminal amino acid sequence of sialoglycoprotein D (glycophorin C) from human erythrocyte membranes.
European journal of biochemistry / FEBS 1982;125(1):57-62.
1982: J K Wright; H Schwarz; E Straub; P Overath; B Bieseler; Konrad Beyreuther
Lactose carrier protein of Escherichia coli. Reconstitution of galactoside binding and countertransport.
European journal of biochemistry / FEBS 1982;124(3):545-52.
1982: Konrad Beyreuther; V Berthold-Schmidt; K Geider
Biological activity and a partial amino-acid sequence of Escherichia coli DNA-binding protein I isolated from overproducing cells.
European journal of biochemistry / FEBS 1982;123(2):415-20.
1982: R Dildrop; M Brüggemann; A Radbruch; Klaus Rajewsky; Konrad Beyreuther
Immunoglobulin V region variants in hybridoma cells. II. Recombination between V genes.
The EMBO journal 1982;1(5):635-40.
1981: Erik R P Zuiderweg; R M Scheek; G Veeneman; J H van Boom; R Kaptein; H Rüterjans; Konrad Beyreuther
1H NMR studies of lac-operator DNA fragments.
Nucleic acids research 1981;9(23):6553-69.
1981: H J Hinz; M Cossmann; Konrad Beyreuther
lac Repressor headpiece constitutes a reversibly unfolding domain.
FEBS letters 1981;129(2):246-8.
1981: R Dildrop; Konrad Beyreuther
C-terminal sequence of the secreted form of mouse IgD heavy chain.
Nature 1981;292(5818):61-3.
1981: W Dahr; M Kordowicz; Konrad Beyreuther; J Krüger
The amino acid sequence of the Mc-specific major red cell membrane sialoglycoprotein--an intermediate of the blood group M- and N-active molecules.
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1981;362(3):363-6.
1981: W Dahr; Konrad Beyreuther; E Gallasch; J Krüger; P Morel
Amino acid sequence of the blood group Mg-specific major human erythrocyte membrane sialoglycoprotein.
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1981;362(1):81-5.
1981: K Trinks; P Habermann; Konrad Beyreuther; P Starlinger; R Ehring
An IS4-encoded protein is synthesized in minicells.
Molecular & general genetics : MGG 1981;182(2):183-8.
1980: Konrad Beyreuther; B Bieseler; R Ehring; H W Griesser; M Mieschendahl; B Müller-Hill; I Triesch
Investigation of structure and function of lactose permease of Escherichia coli.
Biochemical Society transactions 1980;8(6):675-6.
1980: F Buck; H Rüterjans; R Kaptein; Konrad Beyreuther
Photochemically induced dynamic nuclear polarization investigation of complex formation of the NH2-terminal DNA-binding domain of lac repressor with poly[d(AT)].
Proceedings of the National Academy of Sciences of the United States of America 1980;77(9):5145-8.
1980: R Ehring; Konrad Beyreuther; J K Wright; P Overath
In vitro and in vivo products of E. coli lactose permease gene are identical.
Nature 1980;283(5747):537-40.
1980: W Dahr; W Gielen; Konrad Beyreuther; J Krüger
Structure of the Ss blood group antigens. I. Isolation of Ss-active glycopeptides and differentiation of the antigens by modification of methionine.
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1980;361(2):145-52.
1980: T F Meyer; Konrad Beyreuther; K Geider
Recognition of two initiation codons for the synthesis of phage fd gene 2 protein.
Molecular & general genetics : MGG 1980;180(3):489-94.
1980: W Dahr; Konrad Beyreuther; H Steinbach; W Gielen; J Krüger
Structure of the Ss blood group antigens, II: a methionine/threonine polymorphism within the N-terminal sequence of the Ss glycoprotein.
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1980;361(6):895-906.
1979: M Schlotmann; Konrad Beyreuther
Degradation of the DNA-binding domain of wild-type and i-d lac repressors in Escherichia coli.
European journal of biochemistry / FEBS 1979;95(1):39-49.
1978: F Buck; H Rüterjans; Konrad Beyreuther
1H NMR study of the lactose repressor from Escherichia coli.
FEBS letters 1978;96(2):335-8.
1978: Konrad Beyreuther; H Böhmer; P Dimroth
Amino-acid sequence of citrate-lyase acyl-carrier protein from Klebsiella aerogenes.
European journal of biochemistry / FEBS 1978;87(1):101-10.
1977: Konrad Beyreuther; H Raufuss; O Schrecker; W Hengstenberg
The phosphoenolpyruvate-dependent phosphotransferase system of Staphylococcus aureus. 1. Amino-acid sequence of the phosphocarrier protein HPr.
European journal of biochemistry / FEBS 1977;75(1):275-86.
1976: Konrad Beyreuther; B Gronenborn
N-terminal sequence of phage lambda repressor.
Molecular & general genetics : MGG 1976;147(1):115-7.
1975: Konrad Beyreuther; K Adler; E Fanning; C Murray; A Klemm; N Geisler
Amino-acid sequence of lac repressor from Escherichia coli. Isolation, sequence analysis and sequence assembly of tryptic peptides and cyanogen-bromide fragments.
European journal of biochemistry / FEBS 1975;59(2):491-509.
1975: J Horst; F Kluge; Konrad Beyreuther; W Gerok
Gene transfer to human cells: transducing phage lambda plac gene expression in GMI-gangliosidosis fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(9):3531-5.
1973: Konrad Beyreuther; K Adler; N Geisler; A Klemm
The amino-acid sequence of lac repressor.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(12):3576-80.
1973: D R Rao; Konrad Beyreuther; L Jaenicke
A comparative study of pig and sheep-brain glutamine synthetases: tryptic peptides and thiol groups.
European journal of biochemistry / FEBS 1973;35(3):582-92.
1972: K Adler; Konrad Beyreuther; E Fanning; N Geisler; B Gronenborn; A Klemm; B Müller-Hill; M Pfahl; A Schmitz
How lac repressor binds to DNA.
Nature 1972;237(5354):322-7.
1972: Konrad Beyreuther; A Klemm; B Müller-Hill
[How does the lac repressor recognize the lac operator?].
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1972;353(5):693-4.
1969: F Asbeck; Konrad Beyreuther; H Köhler; G von Wettstein; G Braunitzer
[Virus proteins. IV. Constitution of the coat protein of the fd phage].
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1969;350(9):1047-66.
1968: G Braunitzer; Konrad Beyreuther; H Fujiki; B Schrank
[Tetrafluorosuccinic anhydride, a new reagent for the specific and reversible masking of amino groups in proteins].
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1968;349(2):265.
1967: G Braunitzer; F Asbeck; Konrad Beyreuther; H Kohler; G von Wettstein
[The constitution of the coat protein of bacteriophage fd].
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1967;348(12):1689-90.
1967: G Braunitzer; F Asbeck; Konrad Beyreuther; H Köhler; G von Wettstein
[Constitution of the coat protein of bacteriophage fd].
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1967;348(6):725-6.