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Ray Rajotte

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Anatomy

Islets of Langerhans

Chemicals & Drugs

Disorders

Physiology

Graft Survival

Living Beings

Concepts & Ideas

Time Factors

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Co-Publications
Name
99
Warnock, Garth
87
Korbutt, Gregory
74
Lakey, Jonathan
65
Kneteman, Norman
35
Ao, Ziliang
32
Shapiro, James
23
Elliott, John
22
Rabinovitch, Alex
22
Rayat, Gina
18
Suarez-Pinzon, Wilma
16
Thomson, Alan
14
Kin, Tatsuya
14
Clandinin, Thomas
14
Dufour, Jannette
12
Ryan, Edmond

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Publications

TOP 3
Owen Richard J; Mercer John R; Al-Saif Faisal; Molinari Michele; Ashforth Robert A; Rajotte Ray V; Conner-Spady Barbara; Shapiro A M James
Portal vein embolization with radiolabeled polyvinyl alcohol particles in a swine model: hepatic distribution and implications for pancreatic islet cell transplantation.
Seeberger Karen L; Eshpeter Alana; Rajotte Ray V; Korbutt Gregory S
Epithelial cells within the human pancreas do not coexpress mesenchymal antigens: epithelial-mesenchymal transition is an artifact of cell culture.
Jalili Reza B; Forouzandeh Farshad; Moeenrezakhanlou Alireza; Rayat Gina R; Rajotte Ray V; Uludag Hasan; Ghahary Aziz
Mouse pancreatic islets are resistant to indoleamine 2,3 dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function.

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All Publications

2009: Owen Richard J; Mercer John R; Al-Saif Faisal; Molinari Michele; Ashforth Robert A; Rajotte Ray V; Conner-Spady Barbara; Shapiro A M James
Portal vein embolization with radiolabeled polyvinyl alcohol particles in a swine model: hepatic distribution and implications for pancreatic islet cell transplantation.
Cardiovascular and interventional radiology 2009;32(3):499-507.
2009: Seeberger Karen L; Eshpeter Alana; Rajotte Ray V; Korbutt Gregory S
Epithelial cells within the human pancreas do not coexpress mesenchymal antigens: epithelial-mesenchymal transition is an artifact of cell culture.
Laboratory investigation; a journal of technical methods and pathology 2009;89(2):110-21.
2009: Jalili Reza B; Forouzandeh Farshad; Moeenrezakhanlou Alireza; Rayat Gina R; Rajotte Ray V; Uludag Hasan; Ghahary Aziz
Mouse pancreatic islets are resistant to indoleamine 2,3 dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function.
The American journal of pathology 2009;174(1):196-205.
2008: Eshpeter A; Jiang J; Au M; Rajotte R V; Lu K; Lebkowski J S; Majumdar A S; Korbutt G S
In vivo characterization of transplanted human embryonic stem cell-derived pancreatic endocrine islet cells.
Cell proliferation 2008;41(6):843-58.
2008: Rajotte Ray V
Moving towards clinical application.
Xenotransplantation 2008;15(2):113-5.
2008: Rajotte Ray V
Isolation and assessment of islet quality.
Xenotransplantation 2008;15(2):93-5.
2008: Kobayashi Tsunehiro; Arefanian Hossein; Harb George; Tredget Eric B; Rajotte Ray V; Korbutt Gregory S; Rayat Gina R
Prolonged survival of microencapsulated neonatal porcine islet xenografts in immune-competent mice without antirejection therapy.
Cell transplantation 2008;17(10-11):1243-56.
2008: Tredget Eric B; Arefanian Hossein; Gill Ronald G; Rajotte Ray V; Rayat Gina R
Monotherapy with anti-LFA-1 monoclonal antibody promotes long-term survival of rat islet xenografts.
Cell transplantation 2008;17(6):599-608.
2008: Dufour Jannette M; Dass Brinda; Halley Katie R; Korbutt Gregory S; Dixon Doreen E; Rajotte Ray V
Sertoli cell line lacks the immunoprotective properties associated with primary Sertoli cells.
Cell transplantation 2008;17(5):525-34.
2008: Dufour Jannette M; Lord Sarah J; Kin Tatsuya; Rayat Gina R; Dixon Doreen E; Bleackley R Chris; Korbutt Gregory S; Rajotte Ray V
Comparison of successful and unsuccessful islet/Sertoli cell cotransplant grafts in streptozotocin-induced diabetic mice.
Cell transplantation 2008;16(10):1029-38.
2007: Jalili Reza B; Rayat Gina R; Rajotte Ray V; Ghahary Aziz
Suppression of islet allogeneic immune response by indoleamine 2,3 dioxygenase-expressing fibroblasts.
Journal of cellular physiology 2007;213(1):137-43.
2007: Luo B; Chan W F N; Lord S J; Nanji S A; Rajotte R V; Shapiro A M J; Anderson C C
Diabetes induces rapid suppression of adaptive immunity followed by homeostatic T-cell proliferation.
Scandinavian journal of immunology 2007;65(1):22-31.
2007: Arefanian Hossein; Tredget Eric B; Rajotte Ray V; Korbutt Gregory S; Gill Ron G; Rayat Gina R
Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.
Cell transplantation 2007;16(8):787-98.
2007: Lakey Jonathan R T; Kin Tatsuya; Warnock Garth L; Shapiro A M James; Tsapogas Panagiotis; Imes Sharleen; Korbutt Gregory S; Kneteman Norman M; Rajotte Ray V; Ryan Edmond A
Long-term graft function after allogeneic islet transplantation.
Cell transplantation 2007;16(4):441-6.
2006: Kobayashi Tsunehiro; Harb George; Rajotte Ray V; Korbutt Gregory S; Mallett Aaron G; Arefanian Hossein; Mok Dereck; Rayat Gina R
Immune mechanisms associated with the rejection of encapsulated neonatal porcine islet xenografts.
Xenotransplantation 2006;13(6):547-59.
2006: Emamaullee Juliet A; Shapiro A M James; Rajotte Ray V; Korbutt Greg; Elliott John F
Neonatal porcine islets exhibit natural resistance to hypoxia-induced apoptosis.
Transplantation 2006;82(7):945-52.
2006: Sipione Simonetta; Simmen Katia C; Lord Sarah J; Motyka Bruce; Ewen Catherine; Shostak Irene; Rayat Gina R; Dufour Jannette M; Korbutt Greg S; Rajotte Ray V; Bleackley R Chris
Identification of a novel human granzyme B inhibitor secreted by cultured sertoli cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5051-8.
2006: Manji Rizwan A; Zhu Lin F; Nijjar Nimrit K; Rayner David C; Korbutt Greg S; Churchill Thomas A; Rajotte Ray V; Koshal Arvind; Ross David B
Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection.
Circulation 2006;114(4):318-27.
2006: Cardona Kenneth; Korbutt Gregory S; Milas Zvonimir; Lyon James; Cano Jose; Jiang Wanhong; Bello-Laborn Hameeda; Hacquoil Brad; Strobert Elizabeth; Gangappa Shivaprakash; Weber Collin J; Pearson Thomas C; Rajotte Ray V; Larsen Christian P
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways.
Nature medicine 2006;12(3):304-6.
2006: Seeberger Karen L; Dufour Jannette M; Shapiro Andrew M James; Lakey Jonathan R T; Rajotte Ray V; Korbutt Gregory S
Expansion of mesenchymal stem cells from human pancreatic ductal epithelium.
Laboratory investigation; a journal of technical methods and pathology 2006;86(2):141-53.
2005: Gustavson Stephanie M; Rajotte Ray V; Hunkeler David; Lakey Jonathan R T; Edgerton Dale S; Neal Doss W; Snead Wanda L; Penaloza Angelina R; Cherrington Alan D
Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(10):2368-77.
2005: Dufour Jannette M; Rajotte Ray V; Zimmerman Mark; Rezania Alireza; Kin Tatsuya; Dixon Doreen E; Korbutt Gregory S
Development of an ectopic site for islet transplantation, using biodegradable scaffolds.
Tissue engineering 2005;11(9-10):1323-31.
2005: Emamaullee Juliet A; Rajotte Ray V; Liston Peter; Korneluk Robert G; Lakey Jonathan R T; Shapiro A M James; Elliott John F
XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes.
Diabetes 2005;54(9):2541-8.
2005: Meyer Steven R; Nagendran Jeevan; Desai Leena S; Rayat Gina R; Churchill Thomas A; Anderson Colin C; Rajotte Ray V; Lakey Jonathan R T; Ross David B
Decellularization reduces the immune response to aortic valve allografts in the rat.
The Journal of thoracic and cardiovascular surgery 2005;130(2):469-76.
2005: Dufour Jannette M; Hamilton Meredith; Rajotte Ray V; Korbutt Gregory S
Neonatal porcine Sertoli cells inhibit human natural antibody-mediated lysis.
Biology of reproduction 2005;72(5):1224-31.
2005: Kin Tatsuya; Korbutt Gregory S; Kobayashi Tsunehiro; Dufour Jannette M; Rajotte Ray V
Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets.
Diabetes 2005;54(4):1032-9.
2005: Shapiro A M James; Gallant Heather L; Hao Er Geng; Lakey Jonathan R T; McCready Tara; Rajotte Ray V; Yatscoff Randall W; Kneteman Norman M
The portal immunosuppressive storm: relevance to islet transplantation?
Therapeutic drug monitoring 2005;27(1):35-7.
2004: Street Cale N; Lakey Jonathan R T; Shapiro A M James; Imes Sharleen; Rajotte Ray V; Ryan Edmond A; Lyon James G; Kin Tatsuya; Avila Jose; Tsujimura Toshiaki; Korbutt Gregory S
Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome.
Diabetes 2004;53(12):3107-14.
2004: Korbutt G S; Mallett A G; Ao Z; Flashner M; Rajotte R V
Improved survival of microencapsulated islets during in vitro culture and enhanced metabolic function following transplantation.
Diabetologia 2004;47(10):1810-8.
2004: Kin Tatsuya; Rajotte Ray V; Korbutt Gregory S
Reassessment of the vascularization of renal subcapsular islet grafts.
Pancreas 2004;29(3):e59-63.
2004: Manji Jacqueline S; Rajotte Ray V; Koshal Arvind; Manji Rizwan A
Increased apoptosis in porcine cardiac xenografts perfused with human ABO plasma containing the anti-B antibody.
Xenotransplantation 2004;11(4):378-9.
2004: Manji Jacqueline S; Rajotte Ray V; Koshal Arvind; Manji Rizwan A
Human anti-A and anti-B antibodies interact with alphaGal antibody affecting xenograft survival.
Xenotransplantation 2004;11(4):376-7.
2004: Binette Tanya M; Seeberger Karen L; Lyon James G; Rajotte Ray V; Korbutt Gregory S
Porcine endogenous retroviral nucleic acid in peripheral tissues is associated with migration of porcine cells post islet transplant.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(7):1051-60.
2004: Leclerc Isabelle; Woltersdorf Wolfram W; da Silva Xavier Gabriela; Rowe Rebecca L; Cross Sarah E; Korbutt Greg S; Rajotte Ray V; Smith Richard; Rutter Guy A
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.
American journal of physiology. Endocrinology and metabolism 2004;286(6):E1023-31.
2004: Street Cale N; Sipione Simonetta; Helms Lisa; Binette Tanya; Rajotte Ray V; Bleackley R Chris; Korbutt Gregory S
Stem cell-based approaches to solving the problem of tissue supply for islet transplantation in type 1 diabetes.
The international journal of biochemistry & cell biology 2004;36(4):667-83.
2004: Dufour J M; Hemendinger R; Halberstadt C R; Gores P; Emerich D F; Korbutt G S; Rajotte R V
Genetically engineered Sertoli cells are able to survive allogeneic transplantation.
Gene therapy 2004;11(8):694-700.
2004: Street C N; Lakey J R T; Seeberger K; Helms L; Rajotte R V; Shapiro A M J; Korbutt G S
Heterogenous expression of nestin in human pancreatic tissue precludes its use as an islet precursor marker.
The Journal of endocrinology 2004;180(2):213-25.
2004: Manji Rizwan A; Rajotte Ray V; Arvind Koshal
Human O red blood cells and pig-to-human xenotransplantation.
Xenotransplantation 2004;11(1):107.
2004: Street Cale N; Lakey Jonathan R T; Rajotte Ray V; Shapiro A M James; Kieffer Timothy J; Lyon James G; Kin Tatsuya; Korbutt Gregory S
Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently.
The review of diabetic studies : RDS 2004;1(2):66-79.
2004: Norrie Bryan; Jalil Asif; Lakey John R; Rajotte Ray V; Uludag Hasan
In-situ crosslinking thermoreversible polymers for cell entrapment.
Advances in experimental medicine and biology 2004;553():19-28.
2003: Dufour Jannette M; Rajotte Ray V; Seeberger Karen; Kin Tatsuya; Korbutt Gregory S
Long-term survival of neonatal porcine Sertoli cells in non-immunosuppressed rats.
Xenotransplantation 2003;10(6):577-86.
2003: Dufour Jannette M; Rajotte Ray V; Korbutt Gregory S; Emerich Dwaine F
Harnessing the immunomodulatory properties of Sertoli cells to enable xenotransplantation in type I diabetes.
Immunological investigations 2003;32(4):275-97.
2003: Owen Richard J T; Ryan Edmond A; O'Kelly Kevin; Lakey Jonathan R T; McCarthy Mairin C; Paty Breay W; Bigam David L; Kneteman Norman M; Korbutt Gregory S; Rajotte Ray V; Shapiro A M James
Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects.
Radiology 2003;229(1):165-70.
2003: Rayat Gina R; Rajotte Ray V; Lyon James G; Dufour Jannette M; Hacquoil Brad V; Korbutt Gregory S
Immunization with streptozotocin-treated NOD mouse islets inhibits the onset of autoimmune diabetes in NOD mice.
Journal of autoimmunity 2003;21(1):11-5.
2003: Rayat Gina R; Johnson Zachary A; Beilke Joshua N; Korbutt Gregory S; Rajotte Ray V; Gill Ronald G
The degree of phylogenetic disparity of islet grafts dictates the reliance on indirect CD4 T-cell antigen recognition for rejection.
Diabetes 2003;52(6):1433-40.
2003: Lord Sarah J; Rajotte Ray V; Korbutt Gregory S; Bleackley R Chris
Granzyme B: a natural born killer.
Immunological reviews 2003;193():31-8.
2003: Dufour Jannette M; Rajotte Ray V; Kin Tatsuya; Korbutt Gregory S
Immunoprotection of rat islet xenografts by cotransplantation with sertoli cells and a single injection of antilymphocyte serum.
Transplantation 2003;75(9):1594-6.
2003: Rayat G R; Rajotte R V; Hering B J; Binette T M; Korbutt G S
In vitro and in vivo expression of Galalpha-(1,3)Gal on porcine islet cells is age dependent.
The Journal of endocrinology 2003;177(1):127-35.
2003: Gores Paul F; Hayes Daniel H; Copeland M Jane; Korbutt Gregory S; Halberstadt Craig; Kirkpatrick Shaun A; Rajotte Ray V
Long-term survival of intratesticular porcine islets in nonimmunosuppressed beagles.
Transplantation 2003;75(5):613-8.
2003: Manji Rizwan A; Manji Jacqueline S; Koshal Arvind; Korbutt Gregory S; Rajotte Ray V
Human ABO blood group is important in survival and function of porcine working hearts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(3):286-93.
2003: Kin Tatsuya; Korbutt Gregory S; Rajotte Ray V
Survival and metabolic function of syngeneic rat islet grafts transplanted in the omental pouch.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(3):281-5.
2003: Lu W-T; Lakey J R T; Juang J-H; Hsu B R-S; Rajotte R V
Effect of trypsin inhibitor on islet isolation from fresh and cold preserved rat pancreas.
Transplantation proceedings 2003;35(1):488-9.
2003: Street Cale N; Rajotte Ray V; Korbutt Gregory S
Stem cells: a promising source of pancreatic islets for transplantation in type 1 diabetes.
Current topics in developmental biology 2003;58():111-36.
2003: Oberholzer José; Shapiro A M; Lakey Jonathan R; Ryan Edmond A; Rajotte Ray V; Korbutt Gregory S; Morel Philippe; Kneteman Norman M
Current status of islet cell transplantation.
Advances in surgery 2003;37():253-82.
2002: Tsujimura Toshiaki; Kuroda Yoshikazu; Kin Tatsuya; Avila Jose G; Rajotte Ray V; Korbutt Gregory S; Ryan Edmond A; Shapiro A M James; Lakey Jonathan R T
Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method.
Transplantation 2002;74(12):1687-91.
2002: Shapiro A M James; Geng Hao Er; Lakey Jonathan R T; Finegood Diane T; Rajotte Ray V; Kneteman Norman M
Defining optimal immunosuppression for islet transplantation based on reduced diabetogenicity in canine islet autografts.
Transplantation 2002;74(11):1522-8.
2002: Lu W-T; Lakey J R T; Juang J-H; Hsu B R-S; Rajotte R V
Effect of pefabloc on islet isolation from cold preserved rat pancreas.
Transplantation proceedings 2002;34(7):2700-1.
2002: Casey John J; Lakey Jonathan R; Ryan Edmond A; Paty Breay W; Owen Richard; O'Kelly Kevin; Nanji Sulaiman; Rajotte Ray V; Korbutt Gregory S; Bigam David; Kneteman Norman N; Shapiro A M
Portal venous pressure changes after sequential clinical islet transplantation.
Transplantation 2002;74(7):913-5.
2002: Dufour Jannette M; Rajotte Ray V; Korbutt Gregory S
Development of an in vivo model to study testicular morphogenesis.
Journal of andrology 2002;23(5):635-44.
2002: Ryan Edmond A; Lakey Jonathan R T; Paty Breay W; Imes Sharleen; Korbutt Gregory S; Kneteman Norman M; Bigam David; Rajotte Ray V; Shapiro A M James
Successful islet transplantation: continued insulin reserve provides long-term glycemic control.
Diabetes 2002;51(7):2148-57.
2002: Lakey Jonathan R T; Kneteman Norman M; Rajotte Ray V; Wu Douglas C; Bigam David; Shapiro A M James
Effect of core pancreas temperature during cadaveric procurement on human islet isolation and functional viability.
Transplantation 2002;73(7):1106-10.
2002: Rabinovitch Alex; Suarez-Pinzon Wilma L; Shapiro A M James; Rajotte Ray V; Power Robert
Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice.
Diabetes 2002;51(3):638-45.
2002: Kin Tatsuya; Rajotte Ray V; Dufour Jannette M; Korbutt Gregory S
Development of an immunoprivileged site to prolong islet allograft survival.
Cell transplantation 2002;11(6):547-52.
2001: Lakey J R; Suarez-Pinzon W L; Strynadka K; Korbutt G S; Rajotte R V; Mabley J G; Szabó C; Rabinovitch A
Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells.
Laboratory investigation; a journal of technical methods and pathology 2001;81(12):1683-92.
2001: Lakey J R; Anderson T J; Rajotte R V
Novel approaches to cryopreservation of human pancreatic islets.
Transplantation 2001;72(6):1005-11.
2001: Lakey J R; Helms L M; Kin T; Korbutt G S; Rajotte R V; Shapiro A M; Warnock G L
Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemia.
Transplantation 2001;72(4):565-70.
2001: Shapiro A M; Hao E G; Lakey J R; Yakimets W J; Churchill T A; Mitlianga P G; Papadopoulos G K; Elliott J F; Rajotte R V; Kneteman N M
Novel approaches toward early diagnosis of islet allograft rejection.
Transplantation 2001;71(12):1709-18.
2001: Ryan E A; Lakey J R; Rajotte R V; Korbutt G S; Kin T; Imes S; Rabinovitch A; Elliott J F; Bigam D; Kneteman N M; Warnock G L; Larsen I; Shapiro A M
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol.
Diabetes 2001;50(4):710-9.
2001: Fedorow C; McGann L E; Korbutt G S; Rayat G R; Rajotte R V; Lakey J R
Osmotic and cryoprotectant permeation characteristics of islet cells isolated from the newborn pig pancreas.
Cell transplantation 2001;10(7):651-9.
2001: Lakey J R; Rajotte R V; Fedorow C A; Taylor M J
Islet cryopreservation using intracellular preservation solutions.
Cell transplantation 2001;10(7):583-9.
2000: Cheung A T; Dayanandan B; Lewis J T; Korbutt G S; Rajotte R V; Bryer-Ash M; Boylan M O; Wolfe M M; Kieffer T J
Glucose-dependent insulin release from genetically engineered K cells.
Science (New York, N.Y.) 2000;290(5498):1959-62.
2000: Suarez-Pinzon W; Korbutt G S; Power R; Hooton J; Rajotte R V; Rabinovitch A
Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism.
Diabetes 2000;49(11):1810-8.
2000: Rayat G R; Singh B; Korbutt G S; Rajotte R V
Single injection of insulin delays the recurrence of diabetes in syngeneic islet-transplanted diabetic NOD mice.
Transplantation 2000;70(6):976-9.
2000: Shapiro A M; Lakey J R; Ryan E A; Korbutt G S; Toth E; Warnock G L; Kneteman N M; Rajotte R V
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.
The New England journal of medicine 2000;343(4):230-8.
2000: Korbutt G S; Suarez-Pinzon W L; Power R F; Rajotte R V; Rabinovitch A
Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice.
Diabetologia 2000;43(4):474-80.
2000: Rayat G R; Rajotte R V; Ao Z; Korbutt G S
Microencapsulation of neonatal porcine islets: protection from human antibody/complement-mediated cytolysis in vitro and long-term reversal of diabetes in nude mice.
Transplantation 2000;69(6):1084-90.
1999: Rajotte R V
Islet cryopreservation protocols.
Annals of the New York Academy of Sciences 1999;875():200-7.
1999: Rayat G R; Rajotte R V; Korbutt G S
Potential application of neonatal porcine islets as treatment for type 1 diabetes: a review.
Annals of the New York Academy of Sciences 1999;875():175-88.
1999: Rabinovitch A; Suarez-Pinzon W; Strynadka K; Ju Q; Edelstein D; Brownlee M; Korbutt G S; Rajotte R V
Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction.
Diabetes 1999;48(6):1223-9.
1999: Lakey J R; Warnock G L; Shapiro A M; Korbutt G S; Ao Z; Kneteman N M; Rajotte R V
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.
Cell transplantation 1999;8(3):285-92.
1999: Suarez-Pinzon W; Sorensen O; Bleackley R C; Elliott J F; Rajotte R V; Rabinovitch A
Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets.
Diabetes 1999;48(1):21-8.
1998: Rayat G R; Rajotte R V; Elliott J F; Korbutt G S
Expression of Gal alpha(1,3)gal on neonatal porcine islet beta-cells and susceptibility to human antibody/complement lysis.
Diabetes 1998;47(9):1406-11.
1998: Cattral M S; Lakey J R; Warnock G L; Kneteman N M; Rajotte R V
Effect of cryopreservation on the survival and function of murine islet isografts and allografts.
Cell transplantation 1998;7(4):373-9.
1998: Gainer A L; Suarez-Pinzon W L; Min W P; Swiston J R; Hancock-Friesen C; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand.
Transplantation 1998;66(2):194-9.
1998: Rønningen K S; Atrazhev A; Luo L; Luo C; Smith D K; Korbutt G; Rajotte R V; Elliott J F
Anti-BSA antibodies do not cross-react with the 69-kDa islet cell autoantigen ICA69.
Journal of autoimmunity 1998;11(3):223-31.
1998: Suarez-Pinzon W L; Korbutt G S; Rayat G; Sorensen O; Power R F; Rajotte R V; Rabinovitch A
Neonatal porcine islet xenografts in nonobese diabetic mice: effects on blood glucose and analysis of cytokines expressed in the islet grafts.
Transplantation proceedings 1998;30(2):654-5.
1998: Shapiro A M; Hao E; Lakey J R; Elliott J F; Rajotte R V; Kneteman N M
Development of diagnostic markers for islet allograft rejection.
Transplantation proceedings 1998;30(2):647.
1998: Shapiro A M; Gallant H; Hao E; Wong J; Rajotte R; Yatscoff R; Kneteman N
Portal vein immunosuppressant levels and islet graft toxicity.
Transplantation proceedings 1998;30(2):641.
1998: Gainer A L; Suarez-Pinzon W L; Min W P; Hancock-Friesen C; Korbutt G S; Rajotte R V; Rabinovitch A; Warnock G L; Elliott J F
Prolongation of allograft survival of transfected islets expressing human CTLA4-Ig, human soluble Fas ligand or a combination of the two.
Transplantation proceedings 1998;30(2):534.
1998: Shapiro A M; Hao E; Lakey J R; Finegood D; Rajotte R V; Kneteman N M
Diabetogenic synergism in canine islet autografts from cyclosporine and steroids in combination.
Transplantation proceedings 1998;30(2):527.
1998: Ao Z; Suarez-Pinzon W L; Rajotte R V; Korbutt G S; Flashner M; Rabinovitch A
Transplantation of microencapsulated syngeneic and xenogeneic (neonatal porcine) islets in nonobese diabetic mice.
Transplantation proceedings 1998;30(2):500.
1998: Korbutt G S; Ao Z; Flashner M; Elliott J F; Rajotte R V
Coencapsulation of allogeneic islets with allogeneic Sertoli cells prolongs graft survival without systemic immunosuppression.
Transplantation proceedings 1998;30(2):419.
1998: Lakey J R; Warnock G L; Ao Z; Shapiro A M; Korbutt G; Kneteman N; Rajotte R V
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.
Transplantation proceedings 1998;30(2):359.
1998: Rayat G R; Rajotte R V; Elliott J F; Korbutt G S
Gal alpha(1,3)Gal expression on neonatal porcine islet cells and susceptibility to human antibody/complement lysis.
Transplantation proceedings 1998;30(2):325.
1997: Korbutt G S; Ao Z; Flashner M; Rajotte R V
Neonatal porcine islets as a possible source of tissue for humans and microencapsulation improves the metabolic response of islet graft posttransplantation.
Annals of the New York Academy of Sciences 1997;831():294-303.
1997: Rabinovitch A; Suarez-Pinzon W L; Sorensen O; Rajotte R V; Power R F
TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):6298-303.
1997: Rabinovitch A; Suarez-Pinzon W L; Sorensen O; Rajotte R V; Power R F
Combination therapy with cyclosporine and interleukin-4 or interleukin-10 prolongs survival of synergeneic pancreatic islet grafts in nonobese diabetic mice: islet graft survival does not correlate with mRNA levels of type 1 or type 2 cytokines, or transforming growth factor-beta in the islet grafts.
Transplantation 1997;64(11):1525-31.
1997: Rayat G R; Korbutt G S; Elliott J F; Rajotte R V
Survival and function of syngeneic rat islet grafts placed within the thymus versus under the kidney capsule.
Cell transplantation 1997;6(6):597-602.
1997: Korbutt G S; Rayat G R; Ezekowitz J; Rajotte R V
Cryopreservation of rat pancreatic islets: effect of ethylene glycol on islet function and cellular composition.
Transplantation 1997;64(7):1065-70.
1997: Smith D K; Korbutt G S; Suarez-Pinzon W L; Kao D; Rajotte R V; Elliott J F
Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice.
Transplantation 1997;64(7):1040-9.
1997: Reimer R A; Thomson A B; Rajotte R V; Basu T K; Ooraikul B; McBurney M I
A physiological level of rhubarb fiber increases proglucagon gene expression and modulates intestinal glucose uptake in rats.
The Journal of nutrition 1997;127(10):1923-8.
1997: Weber C J; Hagler M K; Chryssochoos J T; Kapp J A; Korbutt G S; Rajotte R V; Linsley P S
CTLA4-Ig prolongs survival of microencapsulated neonatal porcine islet xenografts in diabetic NOD mice.
Cell transplantation 1997;6(5):505-8.
1997: Korbutt G S; Elliott J F; Ao Z; Flashner M; Warnock G L; Rajotte R V
Microencapsulation of neonatal porcine islets: long-term reversal of diabetes in nude mice and in vitro protection from human complement mediated cytolysis.
Transplantation proceedings 1997;29(4):2128.
1997: Lakey J R; Warnock G L; Rajotte R V
Optimization of removal of cryoprotectant from frozen-thawed islets.
Transplantation proceedings 1997;29(4):1986.
1997: Korbutt G S; Ezekowitz J; Rajotte M M; Rayat G; Rajotte R V
Successful cryopreservation of rat islets using ethylene glycol.
Transplantation proceedings 1997;29(4):1983.
1997: Lakey J R; Warnock G L; Brierton M; Ao Z; Hering B J; London N; Ricordi C; Corbin F; Rajotte R V
Development of an automated computer-controlled islet isolation system.
Transplantation proceedings 1997;29(4):1956.
1997: Gainer A L; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Expression of CTLA4-Ig by biolistically transfected mouse islets promotes islet allograft survival.
Transplantation 1997;63(7):1017-21.
1997: Lakey J R; Warnock G L; Rajotte R V
Comparison of methods used for the removal of DMSO following cryopreservation and the development of an automated protocol.
Cell transplantation 1997;6(2):163-72.
1997: Korbutt G S; Elliott J F; Rajotte R V
Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression.
Diabetes 1997;46(2):317-22.
1997: Lakey J R; Warnock G L; Brierton M; Ao Z; Hering B J; London N J; Ricordi C; Corbin F; Rajotte R V
Development of an automated computer-controlled islet isolation system.
Cell transplantation 1997;6(1):47-57.
1997: Korbutt G S; Warlock G L; Rajotte R V
Islet transplantation.
Advances in experimental medicine and biology 1997;426():397-410.
1996: Shapiro A M; Hao E; Rajotte R V; Kneteman N M
High yield of rodent islets with intraductal collagenase and stationary digestion--a comparison with standard technique.
Cell transplantation 1996;5(6):631-8.
1996: Suarez-Pinzon W; Rajotte R V; Mosmann T R; Rabinovitch A
Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction.
Diabetes 1996;45(10):1350-7.
1996: Rabinovitch A; Suarez-Pinzon W L; Strynadka K; Lakey J R; Rajotte R V
Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production.
The Journal of clinical endocrinology and metabolism 1996;81(9):3197-202.
1996: Gainer A L; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Successful biolistic transformation of mouse pancreatic islets while preserving cellular function.
Transplantation 1996;61(11):1567-71.
1996: Lakey J R; Warnock G L; Ao Z; Rajotte R V
Bulk cryopreservation of isolated islets of Langerhans.
Cell transplantation 1996;5(3):395-404.
1996: Korbutt G S; Elliott J F; Ao Z; Smith D K; Warnock G L; Rajotte R V
Large scale isolation, growth, and function of porcine neonatal islet cells.
The Journal of clinical investigation 1996;97(9):2119-29.
1996: Tuitoek P J; Ziari S; Tsin A T; Rajotte R V; Suh M; Basu T K
Streptozotocin-induced diabetes in rats is associated with impaired metabolic availability of vitamin A (retinol).
The British journal of nutrition 1996;75(4):615-22.
1996: Korbutt G S; Aspeslet L; Ao Z; Warnock G L; Ezekowitz J; Koshal A; Rajotte R V; Yatscoff R W
Porcine islet cell antigens are recognized by xenoreactive natural human antibodies of both IgG and IgM subtypes.
Transplantation proceedings 1996;28(2):837-8.
1996: Lakey J R; Yatscoff R W; Koshal A; Rajotte R V
Prolongation of concordant islet xenografts with leflunomide.
Transplantation proceedings 1996;28(2):816.
1996: Lakey J R; Warnock G L; Rajotte R V; Suarez-Alamazor M E; Ao Z; Shapiro A M; Kneteman N M
Variables in organ donors that affect the recovery of human islets of Langerhans.
Transplantation 1996;61(7):1047-53.
1996: Shapiro A M; Hao E; Rajotte R V; Kneteman N M
Impact of Lazaroid U74006F on ischemia and reperfusion injury of islets after transplantation in the rat.
Transplantation proceedings 1996;28(1):85-6.
1996: Lakey J R; Warnock G L; Rajotte R V
Intrathymic transplantation of fresh and cryopreserved islets for the induction of a state of unresponsiveness in rats.
Transplantation 1996;61(3):506-8.
1996: Tuitoek P J; Lakey J R; Rajotte R V; Basu T K
Strain variation in vitamin A (retinol) status of streptozotocin-induced diabetic rats.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1996;66(2):101-5.
1995: Korbutt G S; Smith D K; Rajotte R V; Elliott J F
Expression of beta-galactosidase in mouse pancreatic islets by adenoviral-mediated gene transfer.
Transplantation proceedings 1995;27(6):3414.
1995: Lakey J R; Singh B; Warnock G L; Elliott J F; Rajotte R V
Dose dependence of bacillus Calmette-Guerin on the prevention of autoimmune diabetes in syngeneic islet transplantation.
Transplantation proceedings 1995;27(6):3413.
1995: Rajotte R V; Ao Z; Korbutt G S; Lakey J R; Flashner M; Colby C B; Warnock G L
Cryopreservation of microencapsulated canine islets.
Transplantation proceedings 1995;27(6):3389.
1995: Shapiro A M; Hao E; Rajotte R V; Kneteman N M
Stationary digestion after intraductal collagenase improves islet recovery in the rat.
Transplantation proceedings 1995;27(6):3378.
1995: Ao Z; Korbutt G S; Warnock G L; Flashner M; Colby C B; Rajotte R V
Microencapsulation enhances canine islet survival during long-term culture.
Transplantation proceedings 1995;27(6):3350.
1995: Ao Z; Korbutt G S; Warnock G L; Flashner M; Colby C B; Luskey K L; Rajotte R V
Microencapsulation improves canine islet survival in vivo.
Transplantation proceedings 1995;27(6):3349.
1995: Cattral M S; Lakey J R; Warnock G L; Kneteman N M; Rajotte R V
Effect of cryopreservation on islet recovery and in vivo function.
Transplantation proceedings 1995;27(6):3336.
1995: Gainer A L; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Biolistic transformation of pancreatic islets.
Transplantation proceedings 1995;27(6):3278.
1995: Korbutt G S; Ao Z; Warnock G L; Rajotte R V
Large-scale isolation of viable porcine neonatal islet cell (NIC) aggregates.
Transplantation proceedings 1995;27(6):3267.
1995: Lakey J R; Ao Z; Warnock G L; Korbutt G S; Flashner M; Colby C B; Rajotte R V
Recovery and in vivo function of canine islets cryopreserved in a freezer bag.
Transplantation proceedings 1995;27(6):3266.
1995: Lakey J R; Warnock G L; Rajotte R V; Ao Z; Suarez-Almazor M E; Shapiro A M; Kneteman N M
Factors in cadaveric donors that affect recovery of human islets of Langerhans.
Transplantation proceedings 1995;27(6):3265.
1995: Korbutt G S; Ao Z; Warnock G L; Flashner M; Rajotte R V
Successful reversal of diabetes in nude mice by transplantation of microencapsulated porcine neonatal islet cell aggregates.
Transplantation proceedings 1995;27(6):3212.
1995: Warnock G I; Tsapogas P; Ryan E A; Lakey J R; Korbutt G; Kneteman N M; Ao Z; Rabinovitch A; Rajotte R V
Natural history of insulin independence after transplantation of multidonor cryopreserved pancreatic islets in type 1 diabetic humans.
Transplantation proceedings 1995;27(6):3159-60.
1995: Rabinovitch A; Suarez-Pinzon W L; Sorensen O; Bleackley R C; Power R F; Rajotte R V
Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft.
Transplantation 1995;60(4):368-74.
1995: Lakey J R; Singh B; Warnock G L; Elliott J F; Rajotte R V
Long-term survival of syngeneic islet grafts in BCG-treated diabetic NOD mice can be reversed by cyclophosphamide.
Transplantation 1995;59(12):1751-3.
1995: Lakey J R; Rajotte R V; Warnock G L
Microbial surveillance of human islet isolation, in vitro culture, and cryopreservation.
Clinical and investigative medicine. Médecine clinique et experimentale 1995;18(3):168-76.
1995: Clandinin M T; Wang L C; Rajotte R V; French M A; Goh Y K; Kielo E S
Increasing the dietary polyunsaturated fat content alters whole-body utilization of 16:0 and 10:0.
The American journal of clinical nutrition 1995;61(5):1052-7.
1995: Shapiro A M; Lakey J R; Rajotte R V; Warnock G L; Friedlich M S; Jewell L D; Kneteman N M
Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft.
Transplantation 1995;59(7):1060-3.
1995: Lakey J R; Rajotte R V; Warnock G L; Kneteman N M
Human pancreas preservation prior to islet isolation. Cold ischemic tolerance.
Transplantation 1995;59(5):689-94.
1994: Gainer A L; Lakey J R; Rajotte R V; Warnock G L
Survival and function of human islets subjected to gamma-radiation.
Transplantation proceedings 1994;26(6):3457.
1994: Warnock G L; Lakey J R; Ao Z; Rajotte R V
Tissue banking of cryopreserved islets for clinical islet transplantation.
Transplantation proceedings 1994;26(6):3438.
1994: Lakey J R; Rajotte R V; Warnock G L; Kneteman N M
Cold ischemic tolerance of human pancreas: assessment of islet recovery and in vitro function.
Transplantation proceedings 1994;26(6):3416.
1994: Lakey J R; Warnock G L; Rajotte R V
Conditions for the induction of unresponsiveness to cryopreserved islet allografts with intrathymic islets.
Transplantation proceedings 1994;26(6):3313.
1994: Lakey J R; Warnock G L; Kneteman N M; Ao Z; Rajotte R V
Development of a method for bulk cryopreservation of purified canine islets.
Transplantation proceedings 1994;26(6):3300.
1994: Kneteman N M; Lakey J R; Kizilisik T A; Ao Z; Warnock G L; Rajotte R V
Cadaver pancreas recovery technique. Impact on islet recovery and in vitro function.
Transplantation 1994;58(10):1114-9.
1994: Moussy F; Jakeway S; Harrison D J; Rajotte R V
In vitro and in vivo performance and lifetime of perfluorinated ionomer-coated glucose sensors after high-temperature curing.
Analytical chemistry 1994;66(22):3882-8.
1994: Rabinovitch A; Suarez-Pinzon W L; Strynadka K; Schulz R; Lakey J R; Warnock G L; Rajotte R V
Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production.
The Journal of clinical endocrinology and metabolism 1994;79(4):1058-62.
1994: O'Brien D W; Molnar G D; O'Brien D C; Rajotte R V
Portal vein insulin flux and arterial glucose fluctuations in response to an oral meal test in islet cell-transplanted dogs.
Pancreas 1994;9(5):543-9.
1994: Rabinovitch A; Sorensen O; Suarez-Pinzon W L; Power R F; Rajotte R V; Bleackley R C
Analysis of cytokine mRNA expression in syngeneic islet grafts of NOD mice: interleukin 2 and interferon gamma mRNA expression correlate with graft rejection and interleukin 10 with graft survival.
Diabetologia 1994;37(8):833-7.
1994: Lakey J R; Singh B; Warnock G L; Rajotte R V
BCG immunotherapy prevents recurrence of diabetes in islet grafts transplanted into spontaneously diabetic NOD mice.
Transplantation 1994;57(8):1213-7.
1994: Lakey J R; Rajotte R V; Taylor G D; Kirkland T; Warnock G L
Microbial studies of a tissue bank of cryopreserved human islet cells.
Transplantation proceedings 1994;26(2):827.
1994: Lakey J R; Warnock G L; Kneteman N M; Ao Z; Rajotte R V
Effects of pre-cryopreservation culture on human islet recovery and in vitro function.
Transplantation proceedings 1994;26(2):820.
1994: Lakey J R; Warnock G L; Singh B; Rajotte R V
Adjuvant immunotherapy with Bacillus Calmette-Guerin prevents recurrence of diabetes in islet grafts transplanted into NOD mice.
Transplantation proceedings 1994;26(2):736.
1994: Rajotte R V; Tighe V M; Warnock G L; Kneteman N M; Finegood D T
New site for islet transplantation in rats--liver-mesentery or liver-omental pouch.
Transplantation proceedings 1994;26(2):675.
1994: O'Brien D W; Molnar G D; Rajotte R V
Reduced insulin response from transplanted islet cells impairs regulation of hepatic glucose output.
Transplantation proceedings 1994;26(2):666.
1994: Lakey J R; Kizilisik T A; Rajotte R V; Ao Z; Warnock G L; Kneteman N M
Prospective evaluation of two techniques for human pancreas recovery before islet isolation.
Transplantation proceedings 1994;26(2):589.
1994: Rajotte R V
Cryopreservation of pancreatic islets.
Transplantation proceedings 1994;26(2):395-6.
1994: Portis A J; Rajotte R V; Krukoff T L
Reinnervation of isolated islets of Langerhans transplanted beneath the kidney capsule in the rat.
Cell transplantation 1994;3(2):163-70.
1994: Moussy F; Harrison D J; Rajotte R V
A miniaturized Nafion-based glucose sensor: in vitro and in vivo evaluation in dogs.
The International journal of artificial organs 1994;17(2):88-94.
1994: Warnock G L; Dabbs K D; Cattral M S; Rajotte R V
Improved survival of in vitro cultured canine islet allografts.
Transplantation 1994;57(1):17-22.
1994: Taylor G D; Kirkland T; Lakey J; Rajotte R; Warnock G L
Bacteremia due to transplantation of contaminated cryopreserved pancreatic islets.
Cell transplantation 1994;3(1):103-6.
1994: Tuitoek P J; Thomson A B; Rajotte R V; Basu T K
Intestinal absorption of vitamin A in streptozotocin-induced diabetic rats.
Diabetes research (Edinburgh, Scotland) 1994;25(4):151-8.
1993: Yakimets W J; Lakey J R; Yatscoff R W; Katyal D; Ao Z; Finegood D T; Rajotte R V; Kneteman N M
Prolongation of canine pancreatic islet allograft survival with combined rapamycin and cyclosporine therapy at low doses. Rapamycin efficacy is blood level related.
Transplantation 1993;56(6):1293-8.
1993: Lopaschuk G D; Lakey J R; Barr R; Wambolt R; Thomson A B; Clandinin M T; Rajotte R V
Islet transplantation improves glucose oxidation and mechanical function in diabetic rat hearts.
Canadian journal of physiology and pharmacology 1993;71(12):896-903.
1993: Fabian M C; Lakey J R; Rajotte R V; Kneteman N M
The efficacy and toxicity of rapamycin in murine islet transplantation. In vitro and in vivo studies.
Transplantation 1993;56(5):1137-42.
1993: Ao Z; Matayoshi K; Lakey J R; Rajotte R V; Warnock G L
Survival and function of purified islets in the omental pouch site of outbred dogs.
Transplantation 1993;56(3):524-9.
1993: Moussy F; Harrison D J; O'Brien D W; Rajotte R V
Performance of subcutaneously implanted needle-type glucose sensors employing a novel trilayer coating.
Analytical chemistry 1993;65(15):2072-7.
1993: Lakey J R; Warnock G L; Seelis R E; Ao Z; Kneteman N M; Rajotte R V
Human islet purification with discontinuous density gradients following cold storage of the pancreas.
Transplantation proceedings 1993;25(1 Pt 2):957-8.
1993: Cattral M S; Warnock G L; Kneteman N M; Halloran P F; Rajotte R V
The effect of cryopreservation on the survival and MHC antigen expression of murine islet allografts.
Transplantation 1993;55(1):159-63.
1993: Thomson A B; Keelan M; Lam T; Rajotte R V; Garg M L; Clandinin M T
Fish oil modifies effect of high cholesterol diet on intestinal absorption in diabetic rats.
Diabetes research (Edinburgh, Scotland) 1993;22(4):171-83.
1992: Warnock G L; Ryan E A; Kneteman N M; Ao Z; Lakey J R; Rajotte R V
The natural history of transplantation of insulin-producing pancreatic islets into type I diabetic patients.
Transplantation proceedings 1992;24(6):3058.
1992: Lakey J R; Wang T; Warnock G L; Singh B; Rajotte R V
Prevention of recurrence of insulin-dependent diabetes mellitus in islet cell-transplanted diabetic NOD mice using adjuvant therapy.
Transplantation proceedings 1992;24(6):2848.
1992: Fabian M C; Lakey J R; Rajotte R V; Kneteman N M
Rapamycin prolongs murine islet allograft survival.
Transplantation proceedings 1992;24(6):2842.
1992: Lakey J R; Warnock G L; Seelis R E; Ao Z; Kneteman N M; Rajotte R V
A comparison of human islet purification with discontinuous density gradients of Ficoll prepared with Euro-Collins or medium 199 solution.
Transplantation proceedings 1992;24(6):2825.
1992: Ao Z; Matayoshi K; Yakimets W J; Katyal D; Rajotte R V; Warnock G L
Development of an omental pouch site for islet transplantation.
Transplantation proceedings 1992;24(6):2789.
1992: Ao Z; Lakey J R; Rajotte R V; Warnock G L
Collagenase digestion of canine pancreas by gentle automated dissociation in combination with ductal perfusion optimizes mass recovery of islets.
Transplantation proceedings 1992;24(6):2787.
1992: Ao Z; Matayoshi K; Yakimets W J; Lakey J R; Katyal D; Rajotte R V; Warnock G L
Comparison of dextran and Ficoll density gradients for purification of canine islets.
Transplantation proceedings 1992;24(6):2788.
1992: Tobin B W; Lewis J T; Tobin B L; Rajotte R V; Finegood D T
Markedly reduced beta-cell function does not result in insulin resistance in islet autografted dogs.
Diabetes 1992;41(9):1172-81.
1992: Wang T; Singh B; Warnock G L; Rajotte R V
Prevention of recurrence of IDDM in islet-transplanted diabetic NOD mice by adjuvant immunotherapy.
Diabetes 1992;41(1):114-7.
1992: Warnock G L; Kneteman N M; Ryan E A; Rabinovitch A; Rajotte R V
Long-term follow-up after transplantation of insulin-producing pancreatic islets into patients with type 1 (insulin-dependent) diabetes mellitus.
Diabetologia 1992;35(1):89-95.
1992: Lakey J R; Thomson A B; Keelan M; Lopaschuk G L; Clandinin M T; Cheeseman C I; Rajotte R V
Dietary lipid content influences the clinical and intestinal adaptive responses to islet transplantation in diabetic rats.
Diabetes research (Edinburgh, Scotland) 1992;19(4):149-64.
1991: Cattral M S; Warnock G L; Evans M G; Rajotte R V
Transplantation of purified frozen/thawed canine pancreatic islet allografts with cyclosporine.
Transplantation 1991;52(3):457-61.
1991: Venkatraman J T; Pehowich D; Singh B; Rajotte R V; Thomson A B; Clandinin M T
Effect of dietary fat on diabetes-induced changes in liver microsomal fatty acid composition and glucose-6-phosphatase activity in rats.
Lipids 1991;26(6):441-4.
1991: Lakey J R; Wang L C; Rajotte R V
Optimal temperature in short-term hypothermic preservation of rat pancreas.
Transplantation 1991;51(5):977-81.
1991: Turner R F; Harrison D J; Rajotte R V
Preliminary in vivo biocompatibility studies on perfluorosulphonic acid polymer membranes for biosensor applications.
Biomaterials 1991;12(4):361-8.
1991: O'Brien D W; Semple H A; Molnar G D; Tam Y; Coutts R T; Rajotte R V; Bayens-Simmonds J
A chronic conscious dog model for direct transhepatic studies in normal and pancreatic islet cell transplanted dogs.
Journal of pharmacological methods 1991;25(2):157-70.
1991: Keelan M; Thomson A B; Wierzbicki A A; Wierzbicki E; Rajotte R; Clandinin M T
Isocaloric modification of dietary lipids influences intestinal brush border membrane composition in diabetic rats.
Diabetes research (Edinburgh, Scotland) 1991;16(3):127-38.
1991: Warnock G L; Seelis R E; Kneteman N M; Rajotte R V
Studies of the isolation and transplantation of purified islets in adult humans.
Transplantation proceedings 1991;23(1 Pt 1):787-8.
1991: Dabbs K D; Warnock G L; Cattral M S; Rajotte R V
Reduced immunosuppression for in vitro cultured, pure canine islets transplanted from single donors.
Transplantation proceedings 1991;23(1 Pt 1):781-2.
1991: Cattral M S; Warnock G L; Seelis R E; Rajotte R V
Mass isolation of highly purified islets from the canine pancreas.
Transplantation proceedings 1991;23(1 Pt 1):779-80.
1991: Cattral M S; Warnock G L; Evans M G; Rajotte R V
Transplantation of purified single-donor cryopreserved canine islet allografts with cyclosporine.
Transplantation proceedings 1991;23(1 Pt 1):777-8.
1991: Warnock G L; Kneteman N M; Ryan E; Seelis R E; Rabinovitch A; Rajotte R V
Normoglycaemia after transplantation of freshly isolated and cryopreserved pancreatic islets in type 1 (insulin-dependent) diabetes mellitus.
Diabetologia 1991;34(1):55-8.
1990: Churnratanakul S; Kirdeikis K L; Murphy G K; Wirzba B J; Keelan M; Rajotte R V; Clandinin M T; Thomson A B
Dietary omega-3 fatty acids partially correct the enhanced in vivo uptake of glucose in diabetic rats.
Diabetes research (Edinburgh, Scotland) 1990;15(3):117-23.
1990: O'Brien D W; Molnar G D; Petersen T D; Rajotte R V
The effect of somatostatin on insulin and glucose levels during insulin infusion in anesthetized dogs.
Pancreas 1990;5(6):652-7.
1990: Warnock G L; Kneteman N M; Evans M G; Dabbs K D; Rajotte R V
Comparison of automated and manual methods for islet isolation.
Canadian journal of surgery. Journal canadien de chirurgie 1990;33(5):368-71.
1990: Thomson A B; Keelan M; Rajotte R V; Cheng T; Fedorak R N; Cheeseman C; Clandinin M T
Long-term effects of manipulations of dietary omega-3 fatty acids on clinical control and in vitro uptake of glucose and lipids in diabetic rats.
Diabetes research (Edinburgh, Scotland) 1990;15(2):85-93.
1990: Portis A J; Warnock G L; Finegood D T; Belcastro A N; Rajotte R V
Glucoregulatory response to moderate exercise in long-term islet cell autografted dogs.
Canadian journal of physiology and pharmacology 1990;68(10):1308-12.
1990: Keelan M; Wierzbicki A A; Clandinin M T; Walker K; Rajotte R V; Thomson A B
Dietary fat saturation alters diabetic rat brush border membrane phospholipid fatty acid composition.
Diabetes research (Edinburgh, Scotland) 1990;14(4):159-64.
1990: Evans M G; Warnock G L; Kneteman N M; Rajotte R V
Reversal of diabetes in dogs by transplantation of pure cryopreserved islets.
Transplantation 1990;50(2):202-6.
1990: Rabinovitch A; Sumoski W; Rajotte R V; Warnock G L
Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture.
The Journal of clinical endocrinology and metabolism 1990;71(1):152-6.
1990: Kneteman N M; DeGroot T J; Warnock G L; Rajotte R V
Islet recovery from rat pancreas is altered by procurement technique and flush solution.
Transplantation proceedings 1990;22(2):779.
1990: Warnock G L; Kneteman N M; Rajotte R V
Effect of diabetes on the function of transplanted human islets of Langerhans.
Transplantation proceedings 1990;22(2):804-5.
1990: Kneteman N M; Warnock G L; Evans M G; Dawidson I; Rajotte R V
Islet isolation from human pancreas stored in UW solution for 6 to 26 hours.
Transplantation proceedings 1990;22(2):763-4.
1990: Evans M G; Warnock G L; Kneteman N M; Rajotte R V
Reversal of diabetes by transplantation of pure cryopreserved canine islets.
Transplantation proceedings 1990;22(2):543-4.
1990: Kneteman N M; DeGroot T J; Warnock G L; Rajotte R V
Pancreas preservation prior to islet isolation: evaluation of storage solutions in a rodent model.
Transplantation proceedings 1990;22(2):541-2.
1990: Kneteman N M; Warnock G L; Evans M G; Nason R W; Rajotte R V
Prolonged function of canine pancreatic fragments autotransplanted to the spleen by venous reflux.
Transplantation 1990;49(4):679-81.
1990: Rajotte R V; Evans M G; Warnock G L; Kneteman N M
Islet cryopreservation.
Hormone and metabolic research. Supplement series 1990;25():72-81.
1990: Kneteman N M; DeGroot T J; Warnock G L; Rajotte R V
The evaluation of solutions for pancreas preservation prior to islet isolation.
Hormone and metabolic research. Supplement series 1990;25():4-9.
1990: Kneteman N M; Cattral M C; Warnock G L; Scharp D W; Jaspan J L; Rajotte R V
Immunosuppression and pancreatic islet transplantation.
Hormone and metabolic research. Supplement series 1990;25():193-9.
1990: Warnock G L; Dabbs K D; Evans M G; Cattral M S; Kneteman N M; Rajotte R V
Critical mass of islets that function after implantation in a large mammalian.
Hormone and metabolic research. Supplement series 1990;25():156-61.
1990: Warnock G L; Kneteman N M; Evans M G; Rajotte R V
Isolation of purified large mammal and human islets of Langerhans.
Hormone and metabolic research. Supplement series 1990;25():37-44.
1989: Warnock G L; Kneteman N M; Ryan E A; Evans M G; Seelis R E; Halloran P F; Rabinovitch A; Rajotte R V
Continued function of pancreatic islets after transplantation in type I diabetes.
Lancet 1989;2(8662):570-2.
1989: Kappagoda T; Jayakody L; Rajotte R; Thomson A B; Senaratne M P
Endothelium-dependent relaxation to acetylcholine in the aorta of streptozotocin induced diabetic-rat and the BB-diabetic rat.
Clinical and investigative medicine. Médecine clinique et experimentale 1989;12(3):187-93.
1989: Warnock G L; Cattral M S; Evans M G; Kneteman N M; Rajotte R V
Mass isolation of pure canine islets.
Transplantation proceedings 1989;21(2):3371-2.
1989: Evans M G; Rajotte R V; Warnock G L; Kneteman N M
Viability studies on cryopreserved isolated canine islets of Langerhans.
Transplantation proceedings 1989;21(2):3368-70.
1989: Kneteman N M; Evans M G; Cattral M S; Warnock G L; Rajotte R V
A comparison of canine renal and islet transplantation with cyclosporine: assessment of islet immunogenicity.
Transplantation proceedings 1989;21(2):3366-7.
1989: Warnock G L; Rajotte R V
Effects of precryopreservation culture on survival of rat islets transplanted after slow cooling and rapid thawing.
Cryobiology 1989;26(2):103-11.
1989: Cattral M S; Warnock G L; Kneteman N M; Rajotte R V
Transplantation of purified single-donor canine islet allografts with cyclosporine.
Transplantation 1989;47(4):583-7.
1989: Kneteman N M; Evans M; Nason R; Rajotte R V
Prolonged function of intrasplenic canine pancreatic fragment autografts.
Transplantation proceedings 1989;21(1 Pt 3):2619-20.
1989: Cattral M S; Warnock G L; Kneteman N M; Rajotte R V
Transplantation of single-donor purified canine islets to the spleen or renal subcapsular space with cyclosporine immunosuppression.
Transplantation proceedings 1989;21(1 Pt 3):2695-6.
1989: Warnock G L; Callahan D; Ellis D K; Rajotte R V
Twenty-four-hour hypothermic storage of the canine pancreas before islet isolation.
Transplantation proceedings 1989;21(1 Pt 3):2646-7.
1989: Rajotte R V; Warnock G L; Kneteman N M; Erickson C; Ellis D K
Optimizing cryopreservation of isolated islets.
Transplantation proceedings 1989;21(1 Pt 3):2638-40.
1989: Warnock G L; DeGroot T; Untch D; Ellis D K; Rajotte R V
The natural history of pure canine islet autografts in hepatic or splenic sites.
Transplantation proceedings 1989;21(1 Pt 3):2617-8.
1989: Keelan M; Thomson A B; Clandinin M T; Singh B; Rajotte R; Garg M
Improved intestinal form and function in diabetic rats fed long-term with a polyunsaturated fatty acid diet.
Diabetes research (Edinburgh, Scotland) 1989;10(1):43-7.
1989: Warnock G L; Ellis D K; Cattral M; Untch D; Kneteman N M; Rajotte R V
Viable purified islets of Langerhans from collagenase-perfused human pancreas.
Diabetes 1989;38 Suppl 1():136-9.
1989: Evans M G; Warnock G L; Rajotte R V
Comparison of sites for transplantation of canine pancreatic microfragments.
Diabetes research (Edinburgh, Scotland) 1989;10(1):35-41.
1989: Finegood D T; Warnock G L; Kneteman N M; Rajotte R V
Insulin sensitivity and glucose effectiveness in long-term islet-autotransplanted dogs.
Diabetes 1989;38 Suppl 1():189-91.
1988: Nason R W; Warnock G L; Rajotte R V
Portal versus systemic insulin delivery in canine pancreatic islet cell transplantation.
Transplantation proceedings 1988;20(6):1276-8.
1988: Warnock G L; Cattral M S; Rajotte R V
Normoglycemia after implantation of purified islet cells in dogs.
Canadian journal of surgery. Journal canadien de chirurgie 1988;31(6):421-6.
1988: Singh B; Lauzon J; Venkatraman J; Thomson A B; Rajotte R V; Clandinin M T
Effect of high/low dietary linoleic acid levels on the function and fatty acid composition of T-lymphocytes of normal and diabetic rats.
Diabetes research (Edinburgh, Scotland) 1988;8(3):129-34.
1988: Coulombe M G; Warnock G L; Rajotte R V
Reversal of diabetes by transplantation of cryopreserved rat islets of Langerhans to the renal subcapsular space.
Diabetes research (Edinburgh, Scotland) 1988;8(1):9-15.
1988: Warnock G L; Ellis D; Rajotte R V; Dawidson I; Baekkeskov S; Egebjerg J
Studies of the isolation and viability of human islets of Langerhans.
Transplantation 1988;45(5):957-63.
1988: Warnock G L; Rajotte R V
Critical mass of purified islets that induce normoglycemia after implantation into dogs.
Diabetes 1988;37(4):467-70.
1988: O'Brien D W; Rajotte R V; Molnar G D; Toth K; Petersen T D
Somatostatin increases hepatic insulin extraction.
Diabetes research (Edinburgh, Scotland) 1988;7(4):171-8.
1988: Thomson A B; Keelan M; Clandinin M T; Rajotte R V; Cheeseman C; Walker K
Use of polyunsaturated fatty acid diet to treat the enhanced intestinal uptake of lipids in streptozotocin diabetic rats.
Clinical and investigative medicine. Médecine clinique et experimentale 1988;11(1):57-61.
1988: Nason R W; Rajotte R V; Warnock G L
Pancreatic islet cell transplantation: past, present and future.
Diabetes research (Edinburgh, Scotland) 1988;7(1):1-11.
1988: Rajotte R V; Erickson C L; Clandinin M T; Thomson A B; Singh B
Clinical response to feeding a high polyunsaturated fat diet in normal and diabetic rats.
Diabetes research (Edinburgh, Scotland) 1988;7(1):41-7.
1987: Thomson A B; Keelan M; Clandinin M T; Rajotte R V; Cheeseman C I; Walker K
Treatment of the enhanced intestinal uptake of glucose in diabetic rats with a polyunsaturated fatty acid diet.
Biochimica et biophysica acta 1987;905(2):426-34.
1987: Berzins R; Wieczorek K R; Rajotte R V; Molnar G D; Tam Y K; McGregor J R; Fawcett D M
Accuracy of C-peptide:insulin molar ratio as a measure of hepatic removal of insulin.
Diabetes research and clinical practice 1987;4(1):37-43.
1986: Berzins R; Tam Y K; Molnar G D; Rajotte R V; Wieczorek K R; McGregor J R; Fawcett D M
Pharmacokinetic approach to the estimation of hepatic removal of insulin.
Pancreas 1986;1(6):544-9.
1985: Kneteman N M; Rajotte R V
Isolation and cryopreservation of human pancreatic islets.
Life support systems : the journal of the European Society for Artificial Organs 1985;3 Suppl 1():712-8.
1985: Wieczorek K R; Rajotte R V; Molnar G D; Rumpel F; McGregor J R; Lussier B T; Fawcett D M
Hepatic insulin retention depends on influx in both diabetic and normal dogs.
Clinical and investigative medicine. Médecine clinique et experimentale 1985;8(4):264-71.
1985: Wieczorek K R; Rajotte R V; Molnar G D; McGregor J R; Lussier B T; Fawcett D M
The effect of hepatic insulin influx on insulin retention: comparison of net flux and per cent extraction as indices of hepatic insulin retention.
Clinical and investigative medicine. Médecine clinique et experimentale 1985;8(4):257-63.

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