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Johannes Ramaekers

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Publications

TOP 3
Stefan W Toennes; Cora Wunder; Gerold F Kauert; Manfred R Moeller; Kirsten Schneider; Eef L Theunissen; Johannes G Ramaekers
Influence of ethanol on the pharmacokinetic properties of Δ9-tetrahydrocannabinol in oral fluid.
Silke Conen; Anke Sambeth; Eef L Theunissen; Annemiek Vermeeren; Johannes G Ramaekers
Central nervous system-impairing effects of hydroxyzine as a function of histamine availability.
Wendy M Bosker; Robert S Goodwin; Jussi Hirvonen; Marilyn A Huestis; Robert B Innis; Erin L Karschner; Kim P C Kuypers; Dayong Lee; Eef L Theunissen; Johannes G Ramaekers
Psychomotor function in chronic daily Cannabis smokers during sustained abstinence.

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All Publications

2013: Stefan W Toennes; Cora Wunder; Gerold F Kauert; Manfred R Moeller; Kirsten Schneider; Eef L Theunissen; Johannes G Ramaekers
Influence of ethanol on the pharmacokinetic properties of Δ9-tetrahydrocannabinol in oral fluid.
Journal of analytical toxicology 2013;37(3):152-8.
2013: Silke Conen; Anke Sambeth; Eef L Theunissen; Annemiek Vermeeren; Johannes G Ramaekers
Central nervous system-impairing effects of hydroxyzine as a function of histamine availability.
Journal of clinical psychopharmacology 2013;33(2):276-9.
2013: Wendy M Bosker; Robert S Goodwin; Jussi Hirvonen; Marilyn A Huestis; Robert B Innis; Erin L Karschner; Kim P C Kuypers; Dayong Lee; Eef L Theunissen; Johannes G Ramaekers
Psychomotor function in chronic daily Cannabis smokers during sustained abstinence.
PloS one 2013;8(1):e53127.
2013: Ricarda Jantos; Johannes G Ramaekers; Danica Sabljic; Annemiek Vermeeren; Gisela Skopp
Degradation of zopiclone during storage of spiked and authentic whole blood and matching dried blood spots.
International journal of legal medicine 2013;127(1):69-76.
2012: W M Bosker; S Conen; W K Jeffery; Gerold F Kauert; K P C Kuypers; Manfred R Moeller; Eef L Theunissen; Stefan W Toennes; H C Walls; Johannes G Ramaekers
A placebo-controlled study to assess Standardized Field Sobriety Tests performance during alcohol and cannabis intoxication in heavy cannabis users and accuracy of point of collection testing devices for detecting THC in oral fluid.
Psychopharmacology 2012;223(4):439-46.
2012: Wendy M Bosker; Wayne K Jeffery; Kim P C Kuypers; Gisela Skopp; Anke Surinx; Eef L Theunissen; Cees J van Leeuwen; H Chip Walls; Roos J Blankespoor; Johannes G Ramaekers
Medicinal Δ(9) -tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests.
Addiction (Abingdon, England) 2012;107(10):1837-44.
2012: Johannes G Ramaekers; R Simons; J A Veldstra; K P C Kuypers; M Martens; W M Bosker; Karel A Brookhuis; A Forsman; M Hjälmdahl; A Knoche
Effects of stimulant drugs on actual and simulated driving: perspectives from four experimental studies conducted as part of the DRUID research consortium.
Psychopharmacology 2012;222(3):413-8.
2012: Wendy M Bosker; Silke Conen; Gerold F Kauert; Kim P C Kuypers; Gisela Skopp; Stefan W Toennes; Johannes G Ramaekers
MDMA (ecstasy) effects on actual driving performance before and after sleep deprivation, as function of dose and concentration in blood and oral fluid.
Psychopharmacology 2012;222(3):367-76.
2012: David M Schwope; Johannes G Ramaekers; Wendy M Bosker; David A Gorelick; Marilyn A Huestis
Psychomotor performance, subjective and physiological effects and whole blood Δ⁹-tetrahydrocannabinol concentrations in heavy, chronic cannabis smokers following acute smoked cannabis.
Journal of analytical toxicology 2012;36(6):405-12.
2012: Eef L Theunissen; Stefan W Toennes; Anke Sambeth; Mathieu M Blanchard; Gerold F Kauert; Manfred R Moeller; Johannes G Ramaekers
Neurophysiological functioning of occasional and heavy cannabis users during THC intoxication.
Psychopharmacology 2012;220(2):341-50.
2012: Kim Paula Colette Kuypers; Sara-Ann Legrand; Johannes G Ramaekers; Alain Gaston Verstraete
A case-control study estimating accident risk for alcohol, medicines and illegal drugs.
PloS one 2012;7(8):e43496.
2012: Janelle H P van Wel; Eef L Theunissen; Katja Bakker; Wendy M Bosker; Kim P C Kuypers; Johannes G Ramaekers
Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT2 and 5-HT1 receptors.
PloS one 2012;7(7):e40187.
2011: Kim P C Kuypers; Elia Formisano; Armin Heinecke; Marleen Wingen; Johannes G Ramaekers
MDMA intoxication and verbal memory performance: a placebo-controlled pharmaco-MRI study.
Journal of psychopharmacology (Oxford, England) 2011;25(8):1053-61.
2011: Silke Conen; Eef L Theunissen; Annemiek Vermeeren; Johannes G Ramaekers
Short-term effects of morning versus evening dose of hydroxyzine 50 mg on cognition in healthy volunteers.
Journal of clinical psychopharmacology 2011;31(3):294-301.
2011: Johannes G Ramaekers; Silke Conen; Pieter Jan de Kam; Sabine Braat; Pierre Peeters; Eef L Theunissen; Neely Ivgy-May
Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype.
Psychopharmacology 2011;215(2):321-32.
2011: Stefan W Toennes; Kirsten Schneider; Gerold F Kauert; Cora Wunder; Manfred R Moeller; Eef L Theunissen; Johannes G Ramaekers
Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users.
Analytical and bioanalytical chemistry 2011;400(1):145-52.
2011: Johannes G Ramaekers; Eef L Theunissen; Marjolein de Brouwer; Stefan W Toennes; Manfred R Moeller; Gerhold Kauert
Tolerance and cross-tolerance to neurocognitive effects of THC and alcohol in heavy cannabis users.
Psychopharmacology 2011;214(2):391-401.
2010: Stefan W Toennes; Johannes G Ramaekers; Eef L Theunissen; Manfred R Moeller; Gerold F Kauert
Pharmacokinetic properties of delta9-tetrahydrocannabinol in oral fluid of occasional and chronic users.
Journal of analytical toxicology 2010;34(4):216-21.
2010: Wendy M Bosker; Kim P C Kuypers; Silke Conen; Johannes G Ramaekers
Dose-related effects of MDMA on psychomotor function and mood before, during, and after a night of sleep loss.
Psychopharmacology 2010;209(1):69-76.
2010: Elisabeth A T Evers; Anke Sambeth; Johannes G Ramaekers; Wim J Riedel; Frederik M Van der Veen
The effects of acute tryptophan depletion on brain activation during cognition and emotional processing in healthy volunteers.
Current pharmaceutical design 2010;16(18):1998-2011.
2009: Eef L Theunissen; Javier de la Asuncion Elvira; Dries van den Bergh; Johannes G Ramaekers
Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate.
Journal of clinical psychopharmacology 2009;29(5):439-43.
2009: Johannes G Ramaekers; Kim Kuypers; Marleen Wingen; Armin Heinecke; Elia Formisano
Involvement of inferior parietal lobules in prospective memory impairment during acute MDMA (ecstasy) intoxication: an event-related fMRI study.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(7):1641-8.
2008: Stefan W Toennes; Johannes G Ramaekers; Eef L Theunissen; Manfred R Moeller; Gerold F Kauert
Comparison of cannabinoid pharmacokinetic properties in occasional and heavy users smoking a marijuana or placebo joint.
Journal of analytical toxicology 2008;32(7):470-7.
2008: Marleen Wingen; Kim Kuypers; Vincent van de Ven; Elia Formisano; Johannes G Ramaekers
Sustained attention and serotonin: a pharmaco-fMRI study.
Human psychopharmacology 2008;23(3):221-30.
2007: Franjo Grotenhermen; Gero Leson; Günter Berghaus; Olaf H Drummer; Hans-Peter Krüger; Marie Longo; Herbert Moskowitz; Bud Perrine; Johannes G Ramaekers; Alison Smiley; Rob Tunbridge
Developing limits for driving under cannabis.
Addiction (Abingdon, England) 2007;102(12):1910-7.
2007: Liliane Ferreira Martins; Michel Yegles; Nele Samyn; Johannes G Ramaekers; Robert Wennig
Time-resolved hair analysis of MDMA enantiomers by GC/MS-NCI.
Forensic science international 2007;172(2-3):150-5.
2007: Marleen Wingen; Kim Kuypers; Johannes G Ramaekers
Selective verbal and spatial memory impairment after 5-HT1A and 5-HT2A receptor blockade in healthy volunteers pre-treated with an SSRI.
Journal of psychopharmacology (Oxford, England) 2007;21(5):477-85.
2007: Gerold F Kauert; Johannes G Ramaekers; Erhard Schneider; Manfred R Moeller; Stefan W Toennes
Pharmacokinetic properties of delta9-tetrahydrocannabinol in serum and oral fluid.
Journal of analytical toxicology 2007;31(5):288-93.
2007: Tim R M Leufkens; Annemiek Vermeeren; Beitske E Smink; Peter van Ruitenbeek; Johannes G Ramaekers
Cognitive, psychomotor and actual driving performance in healthy volunteers after immediate and extended release formulations of alprazolam 1 mg.
Psychopharmacology 2007;191(4):951-9.
2007: Kim Kuypers; Marleen Wingen; Nele Samyn; N Limbert; Johannes G Ramaekers
Acute effects of nocturnal doses of MDMA on measures of impulsivity and psychomotor performance throughout the night.
Psychopharmacology 2007;192(1):111-9.
2007: Marleen Wingen; Kim Kuypers; Johannes G Ramaekers
The role of 5-HT1a and 5-HT2a receptors in attention and motor control: a mechanistic study in healthy volunteers.
Psychopharmacology 2007;190(3):391-400.
2007: Günter Berghaus; Johannes G Ramaekers; Olaf H Drummer
Demands on scientific studies in different fields of forensic medicine and forensic sciences. Traffic medicine--impaired driver: alcohol, drugs, diseases.
Forensic science international 2007;165(2-3):233-7.
2007: Kim Kuypers; Johannes G Ramaekers
Acute dose of MDMA (75 mg) impairs spatial memory for location but leaves contextual processing of visuospatial information unaffected.
Psychopharmacology 2007;189(4):557-63.
2006: Cécile Henquet; Araceli Rosa; Lydia Krabbendam; Sergi Papiol; Lourdes Fananás; Marjan Drukker; Johannes G Ramaekers; Jim van Os
An experimental study of catechol-o-methyltransferase Val158Met moderation of delta-9-tetrahydrocannabinol-induced effects on psychosis and cognition.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(12):2748-57.
2006: Johannes G Ramaekers; Manfred R Moeller; Peter van Ruitenbeek; Eef L Theunissen; Erhard Schneider; Gerold F Kauert
Cognition and motor control as a function of Delta9-THC concentration in serum and oral fluid: limits of impairment.
Drug and alcohol dependence 2006;85(2):114-22.
2006: Johannes G Ramaekers; Kim Kuypers; Nele Samyn
Stimulant effects of 3,4-methylenedioxymethamphetamine (MDMA) 75 mg and methylphenidate 20 mg on actual driving during intoxication and withdrawal.
Addiction (Abingdon, England) 2006;101(11):1614-21.
2006: Marleen Wingen; S Langer; Johannes G Ramaekers
Verbal memory performance during subchronic challenge with a selective serotonergic and a mixed action antidepressant.
Human psychopharmacology 2006;21(7):473-9.
2006: Johannes G Ramaekers; Gerold F Kauert; Peter van Ruitenbeek; Eef L Theunissen; Erhard Schneider; Manfred R Moeller
High-potency marijuana impairs executive function and inhibitory motor control.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(10):2296-303.
2006: Marleen Wingen; Johannes G Ramaekers; Jeroen A J Schmitt
Driving impairment in depressed patients receiving long-term antidepressant treatment.
Psychopharmacology 2006;188(1):84-91.
2006: Kim Kuypers; Nele Samyn; Johannes G Ramaekers
MDMA and alcohol effects, combined and alone, on objective and subjective measures of actual driving performance and psychomotor function.
Psychopharmacology 2006;187(4):467-75.
2006: Eef L Theunissen; Marinus J P G Van Kroonenburgh; Jeroen A van Deursen; Ciska Blom-Coenjaerts; Johannes G Ramaekers
Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis.
Psychopharmacology 2006;187(1):95-102.
2006: Eef L Theunissen; Lisa M Jonkman; Kim Kuypers; Johannes G Ramaekers
A combined neurophysiological and behavioural study into the stimulating effects of fexofenadine on performance.
Journal of psychopharmacology (Oxford, England) 2006;20(4):496-505.
2006: Johannes G Ramaekers; Kim Kuypers
Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on behavioral measures of impulsivity: alone and in combination with alcohol.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(5):1048-55.
2006: C T J Lamers; A Bechara; M Rizzo; Johannes G Ramaekers
Cognitive function and mood in MDMA/THC users, THC users and non-drug using controls.
Journal of psychopharmacology (Oxford, England) 2006;20(2):302-11.
2006: Eef L Theunissen; Annemiek Vermeeren; Eric F P M Vuurman; Johannes G Ramaekers
Stimulating effects of H1-antagonists.
Current pharmaceutical design 2006;12(20):2501-9.
2006: Jeroen A J Schmitt; Marleen Wingen; Johannes G Ramaekers; Elisabeth A T Evers; W J Riedel
Serotonin and human cognitive performance.
Current pharmaceutical design 2006;12(20):2473-86.
2006: Eef L Theunissen; Annemiek Vermeeren; Johannes G Ramaekers
Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance.
British journal of clinical pharmacology 2006;61(1):79-86.
2005: Kim Kuypers; Johannes G Ramaekers
Transient memory impairment after acute dose of 75mg 3.4-Methylene-dioxymethamphetamine.
Journal of psychopharmacology (Oxford, England) 2005;19(6):633-9.
2005: Marleen Laloup; Gaëlle Tilman; Viviane Maes; Gert De Boeck; Pierre Wallemacq; Johannes G Ramaekers; Nele Samyn
Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluid.
Forensic science international 2005;153(1):29-37.
2005: Michelle Wood; Marleen Laloup; Maria del Mar Ramirez Fernandez; Kevin M Jenkins; Michael S Young; Johannes G Ramaekers; Gert De Boeck; Nele Samyn
Quantitative analysis of multiple illicit drugs in preserved oral fluid by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Forensic science international 2005;150(2-3):227-38.
2005: Matthew Rizzo; C T J Lamers; C G Sauer; Johannes G Ramaekers; A Bechara; G J Andersen
Impaired perception of self-motion (heading) in abstinent ecstasy and marijuana users.
Psychopharmacology 2005;179(3):559-66.
2005: Marleen Wingen; John Bothmer; Stefan Langer; Johannes G Ramaekers
Actual driving performance and psychomotor function in healthy subjects after acute and subchronic treatment with escitalopram, mirtazapine, and placebo: a crossover trial.
The Journal of clinical psychiatry 2005;66(4):436-43.
2004: Eric F P M Vuurman; G H Rikken; ND Muntjewerff; F de Halleux; Johannes G Ramaekers
Effects of desloratadine, diphenhydramine, and placebo on driving performance and psychomotor performance measurements.
European journal of clinical pharmacology 2004;60(5):307-13.
2004: Johannes G Ramaekers; Günter Berghaus; M van Laar; Olaf H Drummer
Dose related risk of motor vehicle crashes after cannabis use.
Drug and alcohol dependence 2004;73(2):109-19.
2004: Eef L Theunissen; Annemiek Vermeeren; A C M van Oers; I van Maris; Johannes G Ramaekers
A dose-ranging study of the effects of mequitazine on actual driving, memory and psychomotor performance as compared to dexchlorpheniramine, cetirizine and placebo.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(2):250-8.
2003: C T J Lamers; Johannes G Ramaekers; ND Muntjewerff; K L Sikkema; Nele Samyn; N L Read; Karel A Brookhuis; Wim J Riedel
Dissociable effects of a single dose of ecstasy (MDMA) on psychomotor skills and attentional performance.
Journal of psychopharmacology (Oxford, England) 2003;17(4):379-87.
2003: Johannes G Ramaekers
Antidepressants and driver impairment: empirical evidence from a standard on-the-road test.
The Journal of clinical psychiatry 2003;64(1):20-9.
2002: Jeroen A J Schmitt; Johannes G Ramaekers; Monique J Kruizinga; Martin van Boxtel; Eric F P M Vuurman; Wim J Riedel
Additional dopamine reuptake inhibition attenuates vigilance impairment induced by serotonin reuptake inhibition in man.
Journal of psychopharmacology (Oxford, England) 2002;16(3):207-14.
2002: Jeroen A J Schmitt; Wim J Riedel; Eric F P M Vuurman; Monique J Kruizinga; Johannes G Ramaekers
Modulation of the critical flicker fusion effects of serotonin reuptake inhibitors by concomitant pupillary changes.
Psychopharmacology 2002;160(4):381-6.
2002: Annemiek Vermeeren; Johannes G Ramaekers; James F O'Hanlon
Effects of emedastine and cetirizine, alone and with alcohol, on actual driving of males and females.
Journal of psychopharmacology (Oxford, England) 2002;16(1):57-64.
2001: Arjan Blokland; Bart Scholtissen; Annemiek Vermeeren; Johannes G Ramaekers
Dissociable effects of histamine H1 antagonists on reaction-time performance in rats.
Pharmacology, biochemistry, and behavior 2001;70(2-3):427-36.
2000: Johannes G Ramaekers; Annemiek Vermeeren
All antihistamines cross blood-brain barrier.
BMJ (Clinical research ed.) 2000;321(7260):572.
1999: Johannes G Ramaekers; J W Louwerens; ND Muntjewerff; H Milius; A de Bie; P Rosenzweig; Alain Patat; James F O'Hanlon
Psychomotor, Cognitive, extrapyramidal, and affective functions of healthy volunteers during treatment with an atypical (amisulpride) and a classic (haloperidol) antipsychotic.
Journal of clinical psychopharmacology 1999;19(3):209-21.
1998: Johannes G Ramaekers
Behavioural toxicity of medicinal drugs. Practical consequences, incidence, management and avoidance.
Drug safety : an international journal of medical toxicology and drug experience 1998;18(3):189-208.
1997: Johannes G Ramaekers; marc ansseau; ND Muntjewerff; J P Sweens; James F O'Hanlon
Considering the P450 cytochrome system as determining combined effects of antidepressants and benzodiazepines on actual driving performance of depressed outpatients.
International clinical psychopharmacology 1997;12(3):159-69.
1996: Johannes G Ramaekers; M M Uiterwijk; L M van Veggel; G Durrieu; ND Muntjewerff; Alain Patat; James F O'Hanlon
A study of the pharmacodynamic interaction between befloxatone and ethanol on performance and mood in healthy volunteers.
Journal of psychopharmacology (Oxford, England) 1996;10(4):288-94.
1995: Johannes G Ramaekers; ND Muntjewerff; James F O'Hanlon
A comparative study of acute and subchronic effects of dothiepin, fluoxetine and placebo on psychomotor and actual driving performance.
British journal of clinical pharmacology 1995;39(4):397-404.
1995: James F O'Hanlon; Johannes G Ramaekers
Antihistamine effects on actual driving performance in a standard test: a summary of Dutch experience, 1989-94.
Allergy 1995;50(3):234-42.
1994: Johannes G Ramaekers; L M van Veggel; James F O'Hanlon
A cross-study comparison of the effects of moclobemide and brofaromine on actual driving performance and estimated sleep.
Clinical neuropharmacology 1994;17 Suppl 1():S9-18.
1994: Johannes G Ramaekers; James F O'Hanlon
Acrivastine, terfenadine and diphenhydramine effects on driving performance as a function of dose and time after dosing.
European journal of clinical pharmacology 1994;47(3):261-6.
1992: Johannes G Ramaekers; H F Swijgman; James F O'Hanlon
Effects of moclobemide and mianserin on highway driving, psychometric performance and subjective parameters, relative to placebo.
Psychopharmacology 1992;106 Suppl():S62-7.
1992: Johannes G Ramaekers; M M Uiterwijk; James F O'Hanlon
Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving.
European journal of clinical pharmacology 1992;42(4):363-9.