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Nirmala Ramanujam

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TOP 3
Justin Y Lo; Gregory Palmer; J Quincy Brown; Sulochana Dhar; Nan M Jokerst; Bing Yu; Nirmala Ramanujam
Wavelength optimization for quantitative spectral imaging of breast tumor margins.
Sulochana Dhar; Martin A Brooke; Justin Y Lo; Brandon S Nichols; Gregory M Palmer; Nirmala Ramanujam; Bing Yu; Nan M Jokerst
A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays.
Chengbo Liu; Gregory Palmer; Narasimhan Rajaram; Tony Jiang; Karthik Vishwanath; Nirmala Ramanujam
Experimental validation of an inverse fluorescence Monte Carlo model to extract concentrations of metabolically relevant fluorophores from turbid phantoms and a murine tumor model.

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2013: Justin Y Lo; Gregory Palmer; J Quincy Brown; Sulochana Dhar; Nan M Jokerst; Bing Yu; Nirmala Ramanujam
Wavelength optimization for quantitative spectral imaging of breast tumor margins.
PloS one 2013;8(4):e61767.
2012: Sulochana Dhar; Martin A Brooke; Justin Y Lo; Brandon S Nichols; Gregory M Palmer; Nirmala Ramanujam; Bing Yu; Nan M Jokerst
A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays.
Biomedical optics express 2012;3(12):3211-22.
2012: Chengbo Liu; Gregory Palmer; Narasimhan Rajaram; Tony Jiang; Karthik Vishwanath; Nirmala Ramanujam
Experimental validation of an inverse fluorescence Monte Carlo model to extract concentrations of metabolically relevant fluorophores from turbid phantoms and a murine tumor model.
Journal of biomedical optics 2012;17(7):077012.
2012: Torre M Bydlon; Jennifer E Gallagher; Joseph Geradts; Stephanie A Kennedy; William T Barry; J Quincy Brown; Lee G Wilke; Nirmala Ramanujam
Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast.
PloS one 2012;7(12):e51418.
2011: H Wolfgang Beumer; Karthik Vishwanath; Liana Puscas; Hamid R Afshari; Nirmala Ramanujam; Walter T Lee
Detection of squamous cell carcinoma and corresponding biomarkers using optical spectroscopy.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2011;144(3):390-4.
2011: Stacy R Millon; Julie H Ostrander; J Quincy Brown; Anita Raheja; Victoria L Seewaldt; Nirmala Ramanujam
Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines.
Breast cancer research and treatment 2011;126(1):55-62.
2011: Bing Yu; Henry L Fu; Nirmala Ramanujam
Instrument independent diffuse reflectance spectroscopy.
Journal of biomedical optics 2011;16(1):011010.
2010: Vivide Tuan-Chyan Chang; Sarah M Bean; Peter S Cartwright; Nirmala Ramanujam
Visible light optical spectroscopy is sensitive to neovascularization in the dysplastic cervix.
Journal of biomedical optics 2010;15(5):057006.
2010: Julie Hanson Ostrander; Christine M McMahon; Siya Lem; Stacy R Millon; J Quincy Brown; Victoria L Seewaldt; Nirmala Ramanujam
Optical redox ratio differentiates breast cancer cell lines based on estrogen receptor status.
Cancer research 2010;70(11):4759-66.
2010: Torre M Bydlon; Stephanie A Kennedy; Lisa M Richards; J Quincy Brown; Bing Yu; Marlee K Junker; Jennifer Gallagher; Joseph Geradts; Lee G Wilke; Nirmala Ramanujam
Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins.
Optics express 2010;18(8):8058-76.
2010: Erin M Gill; Joely A Straseski; Cathy A Rasmussen; Sara J Liliensiek; Kevin W Eliceiri; Nirmala Ramanujam; John G White; B Lynn Allen-Hoffmann
Visualization of morphological and molecular features associated with chronic ischemia in bioengineered human skin.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2010;16(2):117-31.
2010: Stephanie Kennedy; Joseph Geradts; Torre Bydlon; J Quincy Brown; Jennifer Gallagher; Marlee Junker; William Barry; Nirmala Ramanujam; Lee G Wilke
Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast.
Breast cancer research : BCR 2010;12(6):R91.
2010: Stacy R Millon; Julie H Ostrander; Siavash Yazdanfar; J Quincy Brown; Janelle E Bender; Anita Rajeha; Nirmala Ramanujam
Preferential accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in breast cancer: a comprehensive study on six breast cell lines with varying phenotypes.
Journal of biomedical optics 2010;15(1):018002.
2010: Melissa Skala; Nirmala Ramanujam
Multiphoton redox ratio imaging for metabolic monitoring in vivo.
Methods in molecular biology (Clifton, N.J.) 2010;594():155-62.
2009: Janelle E Bender; Allan B Shang; Eugene W Moretti; Bing Yu; Lisa M Richards; Nirmala Ramanujam
Noninvasive monitoring of tissue hemoglobin using UV-VIS diffuse reflectance spectroscopy: a pilot study.
Optics express 2009;17(26):23396-409.
2009: Karthik Vishwanath; Daniel Klein; Kevin Chang; Thies Schroeder; Mark W Dewhirst; Nirmala Ramanujam
Quantitative optical spectroscopy can identify long-term local tumor control in irradiated murine head and neck xenografts.
Journal of biomedical optics 2009;14(5):054051.
2009: Karthik Vishwanath; Hong Yuan; William T Barry; Mark W Dewhirst; Nirmala Ramanujam
Using optical spectroscopy to longitudinally monitor physiological changes within solid tumors.
Neoplasia (New York, N.Y.) 2009;11(9):889-900.
2009: Janelle E Bender; Karthik Vishwanath; Laura K Moore; J Quincy Brown; Vivide Chang; Gregory Palmer; Nirmala Ramanujam
A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo.
IEEE transactions on bio-medical engineering 2009;56(4):960-8.
2009: Vivide Tuan-Chyan Chang; Peter S Cartwright; Sarah M Bean; Gregory Palmer; Rex C Bentley; Nirmala Ramanujam
Quantitative physiology of the precancerous cervix in vivo through optical spectroscopy.
Neoplasia (New York, N.Y.) 2009;11(4):325-32.
2009: J Quincy Brown; Lee G Wilke; Joseph Geradts; Stephanie A Kennedy; Gregory Palmer; Nirmala Ramanujam
Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo.
Cancer research 2009;69(7):2919-26.
2009: Joseph Y Lo; Bing Yu; Henry L Fu; Janelle E Bender; Gregory Palmer; Thomas F Kuech; Nirmala Ramanujam
A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes.
Optics express 2009;17(3):1372-84.
2009: J Quincy Brown; Karthik Vishwanath; Gregory Palmer; Nirmala Ramanujam
Advances in quantitative UV-visible spectroscopy for clinical and pre-clinical application in cancer.
Current opinion in biotechnology 2009;20(1):119-31.
2009: Nirmala Ramanujam; J Brown; Torre M Bydlon; Stephanie A Kennedy; Lisa M Richards; Marlee K Junker; Jennifer Gallagher; William T Barry; Lee G Wilke; Joseph Geradts
Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009;2009():6554-6.
2008: Bing Yu; Joseph Y Lo; Thomas F Kuech; Gregory Palmer; Janelle E Bender; Nirmala Ramanujam
Cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo.
Journal of biomedical optics 2008;13(6):060505.
2008: Mariya Lazebnik; Changfang Zhu; Gregory Palmer; Josephine Harter; Sarah Sewall; Nirmala Ramanujam; Susan C Hagness
Electromagnetic spectroscopy of normal breast tissue specimens obtained from reduction surgeries: comparison of optical and microwave properties.
IEEE transactions on bio-medical engineering 2008;55(10):2444-51.
2008: Changfang Zhu; Tara M Breslin; Josephine Harter; Nirmala Ramanujam
Model based and empirical spectral analysis for the diagnosis of breast cancer.
Optics express 2008;16(19):14961-78.
2008: Changfang Zhu; Gregory Palmer; Tara M Breslin; Josephine Harter; Nirmala Ramanujam
Diagnosis of breast cancer using fluorescence and diffuse reflectance spectroscopy: a Monte-Carlo-model-based approach.
Journal of biomedical optics 2008;13(3):034015.
2008: Gregory Palmer; Nirmala Ramanujam
Monte-Carlo-based model for the extraction of intrinsic fluorescence from turbid media.
Journal of biomedical optics 2008;13(2):024017.
2007: Melissa Skala; Kristin M Riching; Annette Gendron-Fitzpatrick; Jens Eickhoff; Kevin W Eliceiri; John G White; Nirmala Ramanujam
In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19494-9.
2007: Gregory Palmer; Nirmala Ramanujam
Use of genetic algorithms to optimize fiber optic probe design for the extraction of tissue optical properties.
IEEE transactions on bio-medical engineering 2007;54(8):1533-5.
2007: Melissa Skala; Gregory Palmer; Kristin M Vrotsos; Annette Gendron-Fitzpatrick; Nirmala Ramanujam
Comparison of a physical model and principal component analysis for the diagnosis of epithelial neoplasias in vivo using diffuse reflectance spectroscopy.
Optics express 2007;15(12):7863-75.
2007: Quan Liu; Nirmala Ramanujam
Scaling method for fast Monte Carlo simulation of diffuse reflectance spectra from multilayered turbid media.
Journal of the Optical Society of America. A, Optics, image science, and vision 2007;24(4):1011-25.
2007: Melissa Skala; Kristin M Riching; Damian K Bird; Annette Gendron-Fitzpatrick; Jens Eickhoff; Kevin W Eliceiri; Patricia J Keely; Nirmala Ramanujam
In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia.
Journal of biomedical optics 2007;12(2):024014.
2006: Stacy R Millon; Katherine M Roldan-Perez; Kristin M Riching; Gregory Palmer; Nirmala Ramanujam
Effect of optical clearing agents on the in vivo optical properties of squamous epithelial tissue.
Lasers in surgery and medicine 2006;38(10):920-7.
2006: Changfang Zhu; Gregory Palmer; Tara M Breslin; Josephine Harter; Nirmala Ramanujam
Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique.
Lasers in surgery and medicine 2006;38(7):714-24.
2006: Quan Liu; Nirmala Ramanujam
Sequential estimation of optical properties of a two-layered epithelial tissue model from depth-resolved ultraviolet-visible diffuse reflectance spectra.
Applied optics 2006;45(19):4776-90.
2006: Gregory Palmer; Changfang Zhu; Tara M Breslin; Fushen Xu; Kennedy W Gilchrist; Nirmala Ramanujam
Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis.
Applied optics 2006;45(5):1072-8.
2006: Gregory Palmer; Nirmala Ramanujam
Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms.
Applied optics 2006;45(5):1062-71.
2005: Damian K Bird; Long Yan; Kristin M Vrotsos; Kevin W Eliceiri; Emily Vaughan; Patricia J Keely; John G White; Nirmala Ramanujam
Metabolic mapping of MCF10A human breast cells via multiphoton fluorescence lifetime imaging of the coenzyme NADH.
Cancer research 2005;65(19):8766-73.
2005: Changfang Zhu; Gregory Palmer; Tara M Breslin; Fushen Xu; Nirmala Ramanujam
Use of a multiseparation fiber optic probe for the optical diagnosis of breast cancer.
Journal of biomedical optics 2005;10(2):024032.
2005: Melissa Skala; Jayne M Squirrell; Kristin M Vrotsos; Jens Eickhoff; Annette Gendron-Fitzpatrick; Kevin W Eliceiri; Nirmala Ramanujam
Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues.
Cancer research 2005;65(4):1180-6.
2004: Quan Liu; Nirmala Ramanujam
Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media.
Optics letters 2004;29(17):2034-6.
2004: Carmalyn Lubawy; Nirmala Ramanujam
Endoscopically compatible near-infrared photon migration probe.
Optics letters 2004;29(17):2022-4.
2004: Melissa Skala; Gregory Palmer; Changfang Zhu; Quan Liu; Kristin M Vrotsos; Crystal L Marshek-Stone; Annette Gendron-Fitzpatrick; Nirmala Ramanujam
Investigation of fiber-optic probe designs for optical spectroscopic diagnosis of epithelial pre-cancers.
Lasers in surgery and medicine 2004;34(1):25-38.
2004: Tara M Breslin; Fushen Xu; Gregory Palmer; Changfang Zhu; Kennedy W Gilchrist; Nirmala Ramanujam
Autofluorescence and diffuse reflectance properties of malignant and benign breast tissues.
Annals of surgical oncology 2004;11(1):65-70.
2003: Gregory Palmer; Patricia J Keely; Tara M Breslin; Nirmala Ramanujam
Autofluorescence spectroscopy of normal and malignant human breast cell lines.
Photochemistry and photobiology 2003;78(5):462-9.
2003: Gregory Palmer; Changfang Zhu; Tara M Breslin; Fushen Xu; Kennedy W Gilchrist; Nirmala Ramanujam
Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003).
IEEE transactions on bio-medical engineering 2003;50(11):1233-42.
2003: Erin M Gill; Anais Malpica; Raphael E Alford; Audrey R Nath; Michele Follen; Rebecca Richards-Kortum; Nirmala Ramanujam
Relationship between collagen autofluorescence of the human cervix and menopausal status.
Photochemistry and photobiology 2003;77(6):653-8.
2003: Changfang Zhu; Quan Liu; Nirmala Ramanujam
Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation.
Journal of biomedical optics 2003;8(2):237-47.
2003: Quan Liu; Changfang Zhu; Nirmala Ramanujam
Experimental validation of Monte Carlo modeling of fluorescence in tissues in the UV-visible spectrum.
Journal of biomedical optics 2003;8(2):223-36.
2003: Erin M Gill; Gregory Palmer; Nirmala Ramanujam
Steady-state fluorescence imaging of neoplasia.
Methods in enzymology 2003;361():452-81.
2002: Gregory Palmer; Crystal L Marshek; Kristin M Vrotsos; Nirmala Ramanujam
Optimal methods for fluorescence and diffuse reflectance measurements of tissue biopsy samples.
Lasers in surgery and medicine 2002;30(3):191-200.
2001: Nirmala Ramanujam; J Chen; K Gossage; Rebecca Richards-Kortum; B Chance
Fast and noninvasive fluorescence imaging of biological tissues in vivo using a flying-spot scanner.
IEEE transactions on bio-medical engineering 2001;48(9):1034-41.