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Derrick Rancourt

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Laura C Rose; Ross Fitzsimmons; Roman Krawetz; Poh Lee; Derrick E Rancourt; Hasan Uludağ
Effect of basic fibroblast growth factor in mouse embryonic stem cell culture and osteogenic differentiation.
Huawen Ding; Rose M Geransar; Kevin C Keller; Ivann K C Martinez; Sandra G Nishikawa; Derrick E Rancourt; Kai O zur Nieden; Nicole I zur Nieden
NO-β-catenin crosstalk modulates primitive streak formation prior to embryonic stem cell osteogenic differentiation.
Guoliang Meng; Shiying Liu; Derrick E Rancourt
Synergistic effect of medium, matrix, and exogenous factors on the adhesion and growth of human pluripotent stem cells under defined, xeno-free conditions.

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All Publications

2013: Laura C Rose; Ross Fitzsimmons; Roman Krawetz; Poh Lee; Derrick E Rancourt; Hasan Uludağ
Effect of basic fibroblast growth factor in mouse embryonic stem cell culture and osteogenic differentiation.
Journal of tissue engineering and regenerative medicine 2013;7(5):371-82.
2012: Huawen Ding; Rose M Geransar; Kevin C Keller; Ivann K C Martinez; Sandra G Nishikawa; Derrick E Rancourt; Kai O zur Nieden; Nicole I zur Nieden
NO-β-catenin crosstalk modulates primitive streak formation prior to embryonic stem cell osteogenic differentiation.
Journal of cell science 2012;125(Pt 22):5564-77.
2012: Guoliang Meng; Shiying Liu; Derrick E Rancourt
Synergistic effect of medium, matrix, and exogenous factors on the adhesion and growth of human pluripotent stem cells under defined, xeno-free conditions.
Stem cells and development 2012;21(11):2036-48.
2012: Mehdi Shafa; Kirsten Sjonnesen; Akihiro Yamashita; Michael Kallos; Shiying Liu; Marek Michalak; Derrick E Rancourt
Expansion and long-term maintenance of induced pluripotent stem cells in stirred suspension bioreactors.
Journal of tissue engineering and regenerative medicine 2012;6(6):462-72.
2012: Mehdi Shafa; Akihiro Yamashita; Brad Day; Roman Krawetz; Shiying Liu; Guoliang Meng; Derrick E Rancourt
Derivation of iPSCs in stirred suspension bioreactors.
Nature methods 2012;9(5):465-6.
2012: Roman J Krawetz; Shiying Liu; John R Matyas; Guoliang Meng; Jaymi T Taiani; Yiru Elizabeth Wu; Derrick E Rancourt
Collagen I scaffolds cross-linked with beta-glycerol phosphate induce osteogenic differentiation of embryonic stem cells in vitro and regulate their tumorigenic potential in vivo.
Tissue engineering. Part A 2012;18(9-10):1014-24.
2012: Brad S Thomas; D Lorne J Tyrrell; Navneet Sharma; Oliver F Bathe; Puja Chopra; David H Evans; Kenichi Ito; Sandra Nishikawa; Derrick E Rancourt
Peptide vaccination is superior to genetic vaccination using a recombineered bacteriophage λ subunit vaccine.
Vaccine 2012;30(6):998-1008.
2012: Roman Krawetz; Derrick E Rancourt
Suspension bioreactor expansion of undifferentiated human embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2012;873():227-35.
2012: Guoliang Meng; Derrick E Rancourt
Derivation and maintenance of undifferentiated human embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2012;873():69-80.
2011: Roz Alfred; Roman J Krawetz; Derrick E Rancourt; Jaymi T Taiani; Akihiro Yamashita; Michael Kallos
Large-scale production of murine embryonic stem cell-derived osteoblasts and chondrocytes on microcarriers in serum-free media.
Biomaterials 2011;32(26):6006-16.
2011: Roz Alfred; Jaret Radford; Jessica Fan; Kathryn Boon; Roman Krawetz; Derrick E Rancourt; Michael Kallos
Efficient suspension bioreactor expansion of murine embryonic stem cells on microcarriers in serum-free medium.
Biotechnology progress 2011;27(3):811-23.
2011: Guoliang Meng; Shiying Liu; Derrick E Rancourt
Rapid isolation of undifferentiated human pluripotent stem cells from extremely differentiated colonies.
Stem cells and development 2011;20(4):583-91.
2011: Manbok Kim; K A Garant; Nicole I zur Nieden; Tommy Alain; S D Loken; Stefan J Urbanski; Peter A Forsyth; Derrick E Rancourt; P W K Lee; Randal Johnston
Attenuated reovirus displays oncolysis with reduced host toxicity.
British journal of cancer 2011;104(2):290-9.
2011: Mehdi Shafa; Yuan Zhang; Jerome B Rattner; Henry J Duff; Anna Godollei; Roman Krawetz; Derrick E Rancourt
Impact of stirred suspension bioreactor culture on the differentiation of murine embryonic stem cells into cardiomyocytes.
BMC cell biology 2011;12():53.
2011: Roman J Krawetz; Alexis Greene; Gregory M Kelly; Jaymi Taiani; Derrick E Rancourt
Inhibition of Rho kinase regulates specification of early differentiation events in P19 embryonal carcinoma stem cells.
PloS one 2011;6(11):e26484.
2011: Navneet Sharma; B Renaux; Mahmoud Saifeddine; Morley D Hollenberg; Rajeev Kumar; Koichiro Mihara; Sandra Nishikawa; Rithwik Ramachandran; Derrick E Rancourt
Implantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptors.
PloS one 2011;6(11):e27888.
2010: Nicole I zur Nieden; Lesley A Davis; Derrick E Rancourt
Monolayer cultivation of osteoprogenitors shortens duration of the embryonic stem cell test while reliably predicting developmental osteotoxicity.
Toxicology 2010;277(1-3):66-73.
2010: Mehdi Shafa; Roman Krawetz; Derrick E Rancourt
Returning to the stem state: epigenetics of recapitulating pre-differentiation chromatin structure.
BioEssays : news and reviews in molecular, cellular and developmental biology 2010;32(9):791-9.
2010: Nicole I zur Nieden; Lesley A Davis; Derrick E Rancourt
Comparing three novel endpoints for developmental osteotoxicity in the embryonic stem cell test.
Toxicology and applied pharmacology 2010;247(2):91-7.
2010: Roz Alfred; Tia Gareau; Roman Krawetz; Derrick E Rancourt; Michael Kallos
Serum-free scaled up expansion and differentiation of murine embryonic stem cells to osteoblasts in suspension bioreactors.
Biotechnology and bioengineering 2010;106(5):829-40.
2010: Roman Krawetz; Jaymi T Taiani; Shiying Liu; Guoliang Meng; Xuguang Li; Michael Kallos; Derrick E Rancourt
Large-scale expansion of pluripotent human embryonic stem cells in stirred-suspension bioreactors.
Tissue engineering. Part C, Methods 2010;16(4):573-82.
2010: Jaymi T Taiani; Roman J Krawetz; Nicole I zur Nieden; Yiru Elizabeth Wu; Michael Kallos; John R Matyas; Derrick E Rancourt
Reduced differentiation efficiency of murine embryonic stem cells in stirred suspension bioreactors.
Stem cells and development 2010;19(7):989-98.
2010: Guoliang Meng; Shiying Liu; Xuguang Li; Roman Krawetz; Derrick E Rancourt
Derivation of human embryonic stem cell lines after blastocyst microsurgery.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2010;88(3):479-90.
2010: Guoliang Meng; Shiying Liu; Xuguang Li; Roman Krawetz; Derrick E Rancourt
Extracellular matrix isolated from foreskin fibroblasts supports long-term xeno-free human embryonic stem cell culture.
Stem cells and development 2010;19(4):547-56.
2010: Manbok Kim; Kristina K Hansen; Lesley Davis; Guido Van Marle; Michael John Gill; Julie D Fox; Morley D Hollenberg; Derrick E Rancourt; Patrick Wk Lee; Chae-Ok Yun; Randal N Johnston
Z-FA-FMK as a novel potent inhibitor of reovirus pathogenesis and oncolysis in vivo.
Antiviral therapy 2010;15(6):897-905.
2010: Akihiro Yamashita; Sandi Nishikawa; Derrick E Rancourt
Identification of five developmental processes during chondrogenic differentiation of embryonic stem cells.
PloS one 2010;5(6):e10998.
2010: Akihiro Yamashita; Sandi Nishikawa; Derrick E Rancourt
Microenvironment modulates osteogenic cell lineage commitment in differentiated embryonic stem cells.
PloS one 2010;5(3):e9663.
2009: Roman Krawetz; Yiru Elizabeth Wu; Derrick E Rancourt; John Matyas
Osteoblasts suppress high bone turnover caused by osteolytic breast cancer in-vitro.
Experimental cell research 2009;315(14):2333-42.
2009: Roman J Krawetz; Xuguang Li; Derrick E Rancourt
Human embryonic stem cells: caught between a ROCK inhibitor and a hard place.
BioEssays : news and reviews in molecular, cellular and developmental biology 2009;31(3):336-43.
2009: Xuguang Li; Roman Krawetz; Shiying Liu; Guoliang Meng; Derrick E Rancourt
ROCK inhibitor improves survival of cryopreserved serum/feeder-free single human embryonic stem cells.
Human reproduction (Oxford, England) 2009;24(3):580-9.
2009: Sitar Shah; Heather Smith; Xiaolan Feng; Derrick E Rancourt; Karl Riabowol
ING function in apoptosis in diverse model systems.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2009;87(1):117-25.
2009: A Yamashita; R Krawetz; Derrick E Rancourt
Loss of discordant cells during micro-mass differentiation of embryonic stem cells into the chondrocyte lineage.
Cell death and differentiation 2009;16(2):278-86.
2008: GuoQi Teng; Xian Zhao; James P Lees-Miller; F Russell Quinn; Pin Li; Derrick E Rancourt; Barry London; James C Cross; Henry J Duff
Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality.
Circulation research 2008;103(12):1483-91.
2008: Xuguang Li; Guoliang Meng; Roman Krawetz; Shiying Liu; Derrick E Rancourt
The ROCK inhibitor Y-27632 enhances the survival rate of human embryonic stem cells following cryopreservation.
Stem cells and development 2008;17(6):1079-85.
2008: Navneet Sharma; Katerina Oikonomopoulou; Kenichi Ito; B Renaux; Eleftherios P Diamandis; Morley D Hollenberg; Derrick E Rancourt
Substrate specificity determination of mouse implantation serine proteinase and human kallikrein-related peptidase 6 by phage display.
Biological chemistry 2008;389(8):1097-105.
2008: Navneet Sharma; Jaspreet Kaur; Hui Xu; Nicole Zur Nieden; Derrick E Rancourt
Characterization of secretory leukocyte protease inhibitor as an inhibitor of implantation serine proteinases.
Molecular reproduction and development 2008;75(7):1136-42.
2008: Guoliang Meng; Shiying Liu; Roman Krawetz; Michael Chan; Judy Chernos; Derrick E Rancourt
A novel method for generating xeno-free human feeder cells for human embryonic stem cell culture.
Stem cells and development 2008;17(3):413-22.
2008: G L Meng; Nicole I zur Nieden; Shi Ying Liu; J T Cormier; Michael Kallos; Derrick E Rancourt
Properties of murine embryonic stem cells maintained on human foreskin fibroblasts without LIF.
Molecular reproduction and development 2008;75(4):614-22.
2008: Knut Woltjen; Kenichi Ito; Teruhisa Tsuzuki; Derrick E Rancourt
Orpheus recombination : a comprehensive bacteriophage system for murine targeting vector construction by transplacement.
Methods in molecular biology (Clifton, N.J.) 2008;435():79-94.
2007: Nicole I zur Nieden; Jaymi T Cormier; Derrick E Rancourt; Michael Kallos
Embryonic stem cells remain highly pluripotent following long term expansion as aggregates in suspension bioreactors.
Journal of biotechnology 2007;129(3):421-32.
2007: Nicole I zur Nieden; Feodor D Price; Lesley A Davis; Rebecca E Everitt; Derrick E Rancourt
Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for beta-catenin in osteogenic differentiation.
Molecular endocrinology (Baltimore, Md.) 2007;21(3):674-85.
2006: Jaymi T Cormier; Nicole I zur Nieden; Derrick E Rancourt; Michael Kallos
Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors.
Tissue engineering 2006;12(11):3233-45.
2006: Xiao-Fang Li; Lech Kiedrowski; François Tremblay; Fernando R Fernandez; Marco Perizzolo; Robert J Winkfein; Ray W Turner; Jaideep S Bains; Derrick E Rancourt; Jonathan Lytton
Importance of K+-dependent Na+/Ca2+-exchanger 2, NCKX2, in motor learning and memory.
The Journal of biological chemistry 2006;281(10):6273-82.
2006: Navneet Sharma; Shiying Liu; Lin Tang; Jackie Irwin; Guoliang Meng; Derrick E Rancourt
Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation.
BMC developmental biology 2006;6():61.
2005: Lin Tang; Derrick E Rancourt
Murine implantation serine proteinases 1 and 2: structure, function and evolution.
Gene 2005;364():30-6.
2005: Fiona C Mansergh; Noelle C Orton; John P Vessey; Melanie R Lalonde; William K Stell; Francois Tremblay; Steven Barnes; Derrick E Rancourt; N Torben Bech-Hansen
Mutation of the calcium channel gene Cacna1f disrupts calcium signaling, synaptic transmission and cellular organization in mouse retina.
Human molecular genetics 2005;14(20):3035-46.
2005: Mehrdad Behmanesh; Kunihiko Sakumi; Daisuke Tsuchimoto; Kumiko Torisu; Yoko Ohnishi-Honda; Derrick E Rancourt; Yusaku Nakabeppu
Characterization of the structure and expression of mouse Itpa gene and its related sequences in the mouse genome.
DNA research : an international journal for rapid publication of reports on genes and genomes 2005;12(1):39-51.
2005: Nicole I zur Nieden; Grazyna Kempka; Derrick E Rancourt; Hans-Jürgen Ahr
Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages.
BMC developmental biology 2005;5():1.
2004: Colleen M O'Sullivan; Jillian L R Ungarian; Kuldeep Singh; Shiying Liu; Jackie Hance; Derrick E Rancourt
Uterine secretion of ISP1 & 2 tryptases is regulated by progesterone and estrogen during pregnancy and the endometrial cycle.
Molecular reproduction and development 2004;69(3):252-9.
2004: Colleen M O'Sullivan; Lin Tang; Hui Xu; Shiying Liu; Derrick E Rancourt
Origin of the murine implantation serine proteinase subfamily.
Molecular reproduction and development 2004;69(2):126-36.
2003: Michael A Wride; Fiona C Mansergh; Steffan Adams; Rebecca E Everitt; Stephanie E Minnema; Derrick E Rancourt; Martin J Evans
Expression profiling and gene discovery in the mouse lens.
Molecular vision 2003;9():360-96.
2003: James P Lees-Miller; Jiqing Guo; Julie R Somers; Daniel E Roach; Robert S Sheldon; Derrick E Rancourt; Henry J Duff
Selective knockout of mouse ERG1 B potassium channel eliminates I(Kr) in adult ventricular myocytes and elicits episodes of abrupt sinus bradycardia.
Molecular and cellular biology 2003;23(6):1856-62.
2003: Justyna R Sarna; Matt Larouche; Hassan Marzban; Roy Sillitoe; Derrick E Rancourt; Richard Hawkes
Patterned Purkinje cell degeneration in mouse models of Niemann-Pick type C disease.
The Journal of comparative neurology 2003;456(3):279-91.
2003: Brad Thomas; Knut Woltjen; Derrick E Rancourt
Deep screening of recombination proficient bacteriophage libraries.
BioTechniques 2003;34(1):36-8, 40.
2002: Rebecca E Everitt; S E Minnema; Michael A Wride; C S Koster; Jackie Hance; Fiona C Mansergh; Derrick E Rancourt
RED: the analysis, management and dissemination of expressed sequence tags.
Bioinformatics (Oxford, England) 2002;18(12):1692-3.
2002: Chieko Aoyama; Knut Woltjen; Fiona C Mansergh; Kozo Ishidate; Derrick E Rancourt
Bacteriophage gene targeting vectors generated by transplacement.
BioTechniques 2002;33(4):806-10, 812.
2002: Colleen M O'Sullivan; Shi Ying Liu; J Bradley Karpinka; Derrick E Rancourt
Embryonic hatching enzyme strypsin/ISP1 is expressed with ISP2 in endometrial glands during implantation.
Molecular reproduction and development 2002;62(3):328-34.
2002: Michael A Wride; Fiona C Mansergh; Jamila M Somani; Robert J Winkfein; Derrick E Rancourt
Characterization and in silico mapping of a novel murine zinc finger transcription factor.
Gene 2002;289(1-2):49-59.
2002: Becky S Y Wong; Shiying Liu; Gilbert A Schultz; Derrick E Rancourt
Subtilisin proprotein convertase-6 expression in the mouse uterus during implantation and artificially induced decidualization.
Molecular reproduction and development 2002;61(4):453-9.
2002: Jiaping Xue; Heide A Tarnasky; Derrick E Rancourt; Frans A van Der Hoorn
Targeted disruption of the testicular SPAG5/deepest protein does not affect spermatogenesis or fertility.
Molecular and cellular biology 2002;22(7):1993-7.
2002: Knut Woltjen; M W Todd Unger; Derrick E Rancourt
Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol.
Methods in molecular biology (Clifton, N.J.) 2002;182():189-207.
2001: Colleen M O'Sullivan; Shi Ying Liu; SL Rancourt; Derrick E Rancourt
Regulation of the strypsin-related proteinase ISP2 by progesterone in endometrial gland epithelium during implantation in mice.
Reproduction (Cambridge, England) 2001;122(2):235-44.
2001: Colleen M O'Sullivan; SL Rancourt; Shi Ying Liu; Derrick E Rancourt
A novel murine tryptase involved in blastocyst hatching and outgrowth.
Reproduction (Cambridge, England) 2001;122(1):61-71.
2001: Bhupinder Bhullar; Jennifer Schmidt; T Truong; Derrick E Rancourt; Frans A van Der Hoorn
Germ cell specific promoter drives ectopic transgene expression during embryogenesis.
Molecular reproduction and development 2001;59(1):25-32.
2000: G Bain; Fiona C Mansergh; Michael A Wride; Jackie Hance; A Isogawa; SL Rancourt; William Ray; Y Yoshimura; T Tsuzuki; David I Gottlieb; Derrick E Rancourt
ES cell neural differentiation reveals a substantial number of novel ESTs.
Functional & integrative genomics 2000;1(2):127-39.
2000: MJ Naylor; Derrick E Rancourt; N Torben Bech-Hansen
Isolation and characterization of a calcium channel gene, Cacna1f, the murine orthologue of the gene for incomplete X-linked congenital stationary night blindness.
Genomics 2000;66(3):324-7.
2000: Knut Woltjen; G Bain; Derrick E Rancourt
Retro-recombination screening of a mouse embryonic stem cell genomic library.
Nucleic acids research 2000;28(9):E41.
2000: Fiona C Mansergh; Michael A Wride; Derrick E Rancourt
Neurons from stem cells: implications for understanding nervous system development and repair.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2000;78(5):613-28.
1999: M W Unger; S Y Liu; Derrick E Rancourt
Transplacement mutagenesis: a novel in situ mutagenesis system using phage-plasmid recombination.
Nucleic acids research 1999;27(6):1480-4.
1998: Richard A Woo; Kevin G McLure; Susan Lees-Miller; Derrick E Rancourt; Patrick W K Lee
DNA-dependent protein kinase acts upstream of p53 in response to DNA damage.
Nature 1998;394(6694):700-4.
1998: T Tsuzuki; Derrick E Rancourt
Embryonic stem cell gene targeting using bacteriophage lambda vectors generated by phage-plasmid recombination.
Nucleic acids research 1998;26(4):988-93.
1997: SL Rancourt; Derrick E Rancourt
Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.
Developmental genetics 1997;21(1):75-81.