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Robert Rando

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Cattle

Concepts & Ideas

Anatomy

Chemicals & Drugs

Physiology

Protein Prenylation

Phenomena

Methylation

Genes & Molecular Sequences

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Network (preview)

Co-Publications
Name
8
Gollapalli, Deviprasad
6
Hamasaki, K
6
Cho, J
6
Jahng, Wan Jin
5
Xue, Linlong
5
Pérez-Sala, Dolores
4
Maiti, Pranab
4
Ryu, Do Hyun
4
Bok, Dean
3
Gilbert, BA
3
Siebert, Friedrich
3
Mondal, MS
3
Pajares, María Angeles
2
Ruiz, Alberto
2
Litovchick, Alexander

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Publications

TOP 3
Xue Linlong; Jahng Wan Jin; Gollapalli Deviprasad; Rando Robert R
Palmitoyl transferase activity of lecithin retinol acyl transferase.
Maiti Pranab; Kong Jian; Kim So Ra; Sparrow Janet R; Allikmets Rando; Rando Robert R
Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation.
Maiti Pranab; Gollapalli Deviprasad; Rando Robert R
Specificity of binding of all-trans-retinyl ester to RPE65.

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All Publications

2006: Xue Linlong; Jahng Wan Jin; Gollapalli Deviprasad; Rando Robert R
Palmitoyl transferase activity of lecithin retinol acyl transferase.
Biochemistry 2006;45(35):10710-8.
2006: Maiti Pranab; Kong Jian; Kim So Ra; Sparrow Janet R; Allikmets Rando; Rando Robert R
Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation.
Biochemistry 2006;45(3):852-60.
2005: Maiti Pranab; Gollapalli Deviprasad; Rando Robert R
Specificity of binding of all-trans-retinyl ester to RPE65.
Biochemistry 2005;44(44):14463-9.
2005: Fishkin Nathan; Yefidoff Revital; Gollipalli Deviprasad R; Rando Robert R
On the mechanism of isomerization of all-trans-retinol esters to 11-cis-retinol in retinal pigment epithelial cells: 11-fluoro-all-trans-retinol as substrate/inhibitor in the visual cycle.
Bioorganic & medicinal chemistry 2005;13(17):5189-94.
2004: Gollapalli Deviprasad R; Rando Robert R
The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10030-5.
2004: Xue Linlong; Gollapalli Deviprasad R; Maiti Pranab; Jahng Wan Jin; Rando Robert R
A palmitoylation switch mechanism in the regulation of the visual cycle.
Cell 2004;117(6):761-71.
2004: Xue Linlong; Rando Robert R
Roles of cysteine 161 and tyrosine 154 in the lecithin-retinol acyltransferase mechanism.
Biochemistry 2004;43(20):6120-6.
2003: Gollapalli Deviprasad R; Rando Robert R
Molecular logic of 11-cis-retinoid biosynthesis in a cone-dominated species.
Biochemistry 2003;42(50):14921-9.
2003: Jahng Wan Jin; Xue Linlong; Rando Robert R
Lecithin retinol acyltransferase is a founder member of a novel family of enzymes.
Biochemistry 2003;42(44):12805-12.
2003: Gollapalli Deviprasad R; Maiti Pranab; Rando Robert R
RPE65 operates in the vertebrate visual cycle by stereospecifically binding all-trans-retinyl esters.
Biochemistry 2003;42(40):11824-30.
2003: Gollapalli Deviprasad R; Rando Robert R
Specific inactivation of isomerohydrolase activity by 11-cis-retinoids.
Biochimica et biophysica acta 2003;1651(1-2):93-101.
2003: Litovchick Alexander; Rando Robert R
Stereospecificity of short Rev-derived peptide interactions with RRE IIB RNA.
RNA (New York, N.Y.) 2003;9(8):937-48.
2003: Jahng Wan Jin; David Charles; Nesnas Nasri; Nakanishi Koji; Rando Robert R
A cleavable affinity biotinylating agent reveals a retinoid binding role for RPE65.
Biochemistry 2003;42(20):6159-68.
2003: Bok Dean; Ruiz Alberto; Yaron Orna; Jahng Wan Jin; Ray Arghya; Xue Linlong; Rando Robert R
Purification and characterization of a transmembrane domain-deleted form of lecithin retinol acyltransferase.
Biochemistry 2003;42(20):6090-8.
2003: Gollapalli Deviprasad R; Rando Robert R
All-trans-retinyl esters are the substrates for isomerization in the vertebrate visual cycle.
Biochemistry 2003;42(19):5809-18.
2003: Ryu Do Hyun; Tan Choon-Hong; Rando Robert R
Synthesis of (+),(-)-neamine and their positional isomers as potential antibiotics.
Bioorganic & medicinal chemistry letters 2003;13(5):901-3.
2002: Ryu Do Hyun; Litovchick Alexander; Rando Robert R
Stereospecificity of aminoglycoside-ribosomal interactions.
Biochemistry 2002;41(33):10499-509.
2002: Ryu Do Hyun; Rando Robert R
Decoding region bubble size and aminoglycoside antibiotic binding.
Bioorganic & medicinal chemistry letters 2002;12(16):2241-4.
2002: Jahng Wan Jin; Cheung Eric; Rando Robert R
Lecithin retinol acyltransferase forms functional homodimers.
Biochemistry 2002;41(20):6311-9.
2002: Rando Robert R
Membrane-bound lecithin-retinol acyltransferase.
Biochemical and biophysical research communications 2002;292(5):1243-50.
2001: Ryu D H; Rando R R
Aminoglycoside binding to human and bacterial A-Site rRNA decoding region constructs.
Bioorganic & medicinal chemistry 2001;9(10):2601-8.
2001: Mondal M S; Ruiz A; Hu J; Bok D; Rando R R
Two histidine residues are essential for catalysis by lecithin retinol acyl transferase.
FEBS letters 2001;489(1):14-8.
2000: Tok J B; Cho J; Rando R R
RNA aptamers that specifically bind to a 16S ribosomal RNA decoding region construct.
Nucleic acids research 2000;28(15):2902-10.
2000: Mondal M S; Ruiz A; Bok D; Rando R R
Lecithin retinol acyltransferase contains cysteine residues essential for catalysis.
Biochemistry 2000;39(17):5215-20.
2000: Cho J; Rando R R
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
Nucleic acids research 2000;28(10):2158-63.
2000: Mondal M S; Wang Z; Seeds A M; Rando R R
The specific binding of small molecule isoprenoids to rhoGDP dissociation inhibitor (rhoGDI).
Biochemistry 2000;39(2):406-12.
2000: Parish C A; Rando R R
Isoprenylation/methylation and transducin function.
Methods in enzymology 2000;316():451-64.
2000: Winston A; Rando R R
Quantitative measurements of isomerohydrolase activity.
Methods in enzymology 2000;316():324-30.
1999: Cho J; Rando R R
Specificity in the binding of aminoglycosides to HIV-RRE RNA.
Biochemistry 1999;38(26):8548-54.
1999: Ruiz A; Winston A; Lim Y H; Gilbert B A; Rando R R; Bok D
Molecular and biochemical characterization of lecithin retinol acyltransferase.
The Journal of biological chemistry 1999;274(6):3834-41.
1999: Tok J B; Cho J; Rando R R
Aminoglycoside antibiotics are able to specifically bind the 5'-untranslated region of thymidylate synthase messenger RNA.
Biochemistry 1999;38(1):199-206.
1998: Choo D W; Cheung E; Rando R R
Lack of effect of RPE65 removal on the enzymatic processing of all-trans-retinol into 11-cis-retinol in vitro.
FEBS letters 1998;440(1-2):195-8.
1998: Hamasaki K; Rando R R
A high-throughput fluorescence screen to monitor the specific binding of antagonists to RNA targets.
Analytical biochemistry 1998;261(2):183-90.
1998: Pérez-Sala D; Gilbert B A; Rando R R; Cañada F J
Analogs of farnesylcysteine induce apoptosis in HL-60 cells.
FEBS letters 1998;426(3):319-24.
1998: Cho J; Hamasaki K; Rando R R
The binding site of a specific aminoglycoside binding RNA molecule.
Biochemistry 1998;37(14):4985-92.
1998: Winston A; Rando R R
Regulation of isomerohydrolase activity in the visual cycle.
Biochemistry 1998;37(7):2044-50.
1998: Hamasaki K; Killian J; Cho J; Rando R R
Minimal RNA constructs that specifically bind aminoglycoside antibiotics with high affinities.
Biochemistry 1998;37(2):656-63.
1997: Hamasaki K; Rando R R
Specific binding of aminoglycosides to a human rRNA construct based on a DNA polymorphism which causes aminoglycoside-induced deafness.
Biochemistry 1997;36(40):12323-8.
1997: Gilbert B A; Sha M; Wathen S T; Rando R R
RNA aptamers that specifically bind to a K Ras-derived farnesylated peptide.
Bioorganic & medicinal chemistry 1997;5(6):1115-22.
1997: Parish C A; Brazil D P; Rando R R
On the mechanism of the inhibition of transducin function by farnesylcysteine analogs.
Biochemistry 1997;36(9):2686-93.
1997: Wang Y; Hamasaki K; Rando R R
Specificity of aminoglycoside binding to RNA constructs derived from the 16S rRNA decoding region and the HIV-RRE activator region.
Biochemistry 1997;36(4):768-79.
1996: Wang Y; Killian J; Hamasaki K; Rando R R
RNA molecules that specifically and stoichiometrically bind aminoglycoside antibiotics with high affinities.
Biochemistry 1996;35(38):12338-46.
1996: Rando R R
Chemical biology of isoprenylation/methylation.
Biochemical Society transactions 1996;24(3):682-87.
1996: Parish C A; Rando R R
Isoprenylation/methylation of proteins enhances membrane association by a hydrophobic mechanism.
Biochemistry 1996;35(26):8473-7.
1996: Parish C A; Smrcka A V; Rando R R
The role of G protein methylation in the function of a geranylgeranylated beta gamma isoform.
Biochemistry 1996;35(23):7499-505.
1996: Rando R R
Polyenes and vision.
Chemistry & biology 1996;3(4):255-62.
1996: Rando R R
Chemical biology of protein isoprenylation/methylation.
Biochimica et biophysica acta 1996;1300(1):5-16.
1996: Chen Y; Ma Y T; Rando R R
Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease.
Biochemistry 1996;35(10):3227-37.
1995: Cheng H; Parish C A; Gilbert B A; Rando R R
A novel endoprotease responsible for the specific cleavage of transducin gamma subunit.
Biochemistry 1995;34(51):16662-71.
1995: Parish C A; Smrcka A V; Rando R R
Functional significance of beta gamma-subunit carboxymethylation for the activation of phospholipase C and phosphoinositide 3-kinase.
Biochemistry 1995;34(23):7722-7.
1995: Wang Y; Rando R R
Specific binding of aminoglycoside antibiotics to RNA.
Chemistry & biology 1995;2(5):281-90.
1995: Gilbert B A; Lim Y H; Ding J; Badwey J A; Rando R R
Farnesyl thiotriazole, a potent neutrophil agonist and structurally novel activator of protein kinase C.
Biochemistry 1995;34(12):3916-20.
1995: Bernstein P S; Choi S Y; Ho Y C; Rando R R
Photoaffinity labeling of retinoic acid-binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(3):654-8.
1995: Ma Y T; Gilbert B A; Rando R R
Farnesylcysteine analogs to probe role of prenylated protein methyltransferase.
Methods in enzymology 1995;250():226-34.
1995: Gilbert B A; Ma Y T; Rando R R
Inhibitors of prenylated protein endoprotease.
Methods in enzymology 1995;250():206-15.
1994: Giner J L; Rando R R
Novel methyltransferase activity modifying the carboxy terminal bis(geranylgeranyl)-Cys-Ala-Cys structure of small GTP-binding proteins.
Biochemistry 1994;33(50):15116-23.
1994: Urbach J; Rando R R
Thiol dependent isomerization of all-trans-retinoic acid to 9-cis-retinoic acid.
FEBS letters 1994;351(3):429-32.
1994: Parish C A; Rando R R
Functional significance of G protein carboxymethylation.
Biochemistry 1994;33(33):9986-91.
1994: Ding J; Lu D J; Pérez-Sala D; Ma Y T; Maddox J F; Gilbert B A; Badwey J A; Rando R R
Farnesyl-L-cysteine analogs can inhibit or initiate superoxide release by human neutrophils.
The Journal of biological chemistry 1994;269(24):16837-44.
1994: Ma Y T; Shi Y Q; Lim Y H; McGrail S H; Ware J A; Rando R R
Mechanistic studies on human platelet isoprenylated protein methyltransferase: farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase.
Biochemistry 1994;33(18):5414-20.
1994: Urbach J; Rando R R
Isomerization of all-trans-retinoic acid to 9-cis-retinoic acid.
The Biochemical journal 1994;299 ( Pt 2)():459-65.
1994: Rando R R; Ma Y T
Isoprenylated protein endopeptidase.
Methods in enzymology 1994;244():632-9.
1993: Ma Y T; Rando R R
Endoproteolysis of non-CAAX-containing isoprenylated peptides.
FEBS letters 1993;332(1-2):105-10.
1993: Furuyoshi S; Shi Y Q; Rando R R
Acyl group transfer from the sn-1 position of phospholipids in the biosynthesis of n-dodecyl palmitate.
Biochemistry 1993;32(20):5425-30.
1993: Shi Y Q; Furuyoshi S; Hubacek I; Rando R R
Affinity labeling of lecithin retinol acyltransferase.
Biochemistry 1993;32(12):3077-80.
1993: Ma Y T; Gilbert B A; Rando R R
Inhibitors of the isoprenylated protein endoprotease.
Biochemistry 1993;32(9):2386-93.
1993: Shi Y Q; Hubacek I; Rando R R
Kinetic mechanism of lecithin retinol acyl transferase.
Biochemistry 1993;32(5):1257-63.
1992: Rando R R
Molecular mechanisms in visual pigment regeneration.
Photochemistry and photobiology 1992;56(6):1145-56.
1992: Ma Y T; Chaudhuri A; Rando R R
Substrate specificity of the isoprenylated protein endoprotease.
Biochemistry 1992;31(47):11772-7.
1992: Ma Y T; Rando R R
A microsomal endoprotease that specifically cleaves isoprenylated peptides.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(14):6275-9.
1992: Pérez-Sala D; Gilbert B A; Tan E W; Rando R R
Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates.
The Biochemical journal 1992;284 ( Pt 3)():835-40.
1992: Tan E W; Rando R R
Identification of an isoprenylated cysteine methyl ester hydrolase activity in bovine rod outer segment membranes.
Biochemistry 1992;31(24):5572-8.
1992: Shi Y Q; Rando R R
Kinetic mechanism of isoprenylated protein methyltransferase.
The Journal of biological chemistry 1992;267(14):9547-51.
1992: Rando R R; Kishi Y
Structural basis of protein kinase C activation by diacylglycerols and tumor promoters.
Biochemistry 1992;31(8):2211-8.
1991: Tan E W; Pérez-Sala D; Cañada F J; Rando R R
Identifying the recognition unit for G protein methylation.
The Journal of biological chemistry 1991;266(17):10719-22.
1991: Pérez-Sala D; Tan E W; Cañada F J; Rando R R
Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3043-6.
1991: Ganter U M; Longstaff C; Pajares M A; Rando R R; Siebert F
Fourier transform infrared studies of active-site-methylated rhodopsin. Implications for chromophore-protein interaction, transducin activation, and the reaction pathway.
Biophysical journal 1991;59(3):640-4.
1991: Kong F H; Kishi Y; Perez-Sala D; Rando R R
The pharmacophore of debromoaplysiatoxin responsible for protein kinase C activation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1973-6.
1991: Rando R R
Membrane phospholipids and the dark side of vision.
Journal of bioenergetics and biomembranes 1991;23(1):133-46.
1991: Rando R R
Membrane phospholipids as an energy source in the operation of the visual cycle.
Biochemistry 1991;30(3):595-602.
1990: Kong F; Kishi Y; Perez-Sala D; Rando R R
The stereochemical requirement for protein kinase C activation by 3-methyldiglycerides matches that found in naturally occurring tumor promoters aplysiatoxins.
FEBS letters 1990;274(1-2):203-6.
1990: Cañada F J; Law W C; Rando R R; Yamamoto T; Derguini F; Nakanishi K
Substrate specificities and mechanism in the enzymatic processing of vitamin A into 11-cis-retinol.
Biochemistry 1990;29(41):9690-7.
1990: Lai R K; Perez-Sala D; Cañada F J; Rando R R
The gamma subunit of transducin is farnesylated.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7673-7.
1990: Kräutle R; Gärtner W; Ganter U M; Longstaff C; Rando R R; Siebert F
The photoreaction of active-site-methylated bacteriorhodopsin: an investigation using static and time-resolved infrared difference spectroscopy.
Biochemistry 1990;29(16):3915-23.
1990: Trehan A; Cañada F J; Rando R R
Inhibitors of retinyl ester formation also prevent the biosynthesis of 11-cis-retinol.
Biochemistry 1990;29(2):309-12.
1989: Seckler B; Rando R R
Schiff-base deprotonation is mandatory for light-dependent rhodopsin phosphorylation.
The Biochemical journal 1989;264(2):489-93.
1989: Nakamura H; Kishi Y; Pajares M A; Rando R R
Structural basis of protein kinase C activation by tumor promoters.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9672-6.
1989: Ganter U M; Schmid E D; Perez-Sala D; Rando R R; Siebert F
Removal of the 9-methyl group of retinal inhibits signal transduction in the visual process. A Fourier transform infrared and biochemical investigation.
Biochemistry 1989;28(14):5954-62.
1989: Barry R J; Cañada F J; Rando R R
Solubilization and partial purification of retinyl ester synthetase and retinoid isomerase from bovine ocular pigment epithelium.
The Journal of biological chemistry 1989;264(16):9231-8.
1989: Law W C; Rando R R
The molecular basis of retinoic acid induced night blindness.
Biochemical and biophysical research communications 1989;161(2):825-9.
1989: Deigner P S; Law W C; Cañada F J; Rando R R
Membranes as the energy source in the endergonic transformation of vitamin A to 11-cis-retinol.
Science (New York, N.Y.) 1989;244(4907):968-71.
1989: Pajares M A; Rando R R
The active-site environment of rhodopsin.
The Journal of biological chemistry 1989;264(12):6804-9.
1988: Molleyres L P; Rando R R
Structural studies on the diglyceride-mediated activation of protein kinase C.
The Journal of biological chemistry 1988;263(29):14832-8.
1988: Rando R R
Regulation of protein kinase C activity by lipids.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(8):2348-55.
1988: Law W C; Rando R R
Stereochemical inversion at C-15 accompanies the enzymatic isomerization of all-trans- to 11-cis-retinoids.
Biochemistry 1988;27(11):4147-52.
1987: Bernstein P S; Law W C; Rando R R
Biochemical characterization of the retinoid isomerase system of the eye.
The Journal of biological chemistry 1987;262(35):16848-57.
1987: Fulton B S; Rando R R
Biosynthesis of 11-cis-retinoids and retinyl esters by bovine pigment epithelium membranes.
Biochemistry 1987;26(24):7938-45.
1987: Longstaff C; Rando R R
Deprotonation of the Schiff base of bacteriorhodopsin is obligate in light-induced proton pumping.
Biochemistry 1987;26(19):6107-13.
1987: Bernstein P S; Law W C; Rando R R
Isomerization of all-trans-retinoids to 11-cis-retinoids in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(7):1849-53.

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