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Michael Rape

Research Profile

Chemicals & Drugs

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Anatomy

Hela Cells

Physiology

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Mitosis

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Publications

TOP 3
Colleen A McGourty; Michael Rape
Cullin' PLK1 from kinetochores.
Adam Williamson; Achim Werner; Michael Rape
The Colossus of ubiquitylation: decrypting a cellular code.
Lingyan Jin; Kanika Bajaj Pahuja; Christine Baumgärtel; Amita Gorur; Randy Schekman; Katherine E Wickliffe; Michael Rape
Ubiquitin-dependent regulation of COPII coat size and function.

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All Publications

2013: Colleen A McGourty; Michael Rape
Cullin' PLK1 from kinetochores.
Nature cell biology 2013;15(4):347-8.
2013: Adam Williamson; Achim Werner; Michael Rape
The Colossus of ubiquitylation: decrypting a cellular code.
Molecular cell 2013;49(4):591-600.
2012: Lingyan Jin; Kanika Bajaj Pahuja; Christine Baumgärtel; Amita Gorur; Randy Schekman; Katherine E Wickliffe; Michael Rape
Ubiquitin-dependent regulation of COPII coat size and function.
Nature 2012;482(7386):495-500.
2012: Annamaria Mocciaro; Michael Rape
Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control.
Journal of cell science 2012;125(Pt 2):255-63.
2012: David Komander; Michael Rape
The ubiquitin code.
Annual review of biochemistry 2012;81():203-29.
2012: Kim Newton; Michael Rape; Katherine E Wickliffe; Ronald E Ferrando; Robert F Kelley; Marissa L Matsumoto; Vishva M Dixit
Using linkage-specific monoclonal antibodies to analyze cellular ubiquitylation.
Methods in molecular biology (Clifton, N.J.) 2012;832():185-96.
2011: Katherine E Wickliffe; Adam Williamson; Aileen Kelly; Hermann-Josef Meyer; Michael Rape
K11-linked ubiquitin chains as novel regulators of cell division.
Trends in cell biology 2011;21(11):656-63.
2011: Hermann-Josef Meyer; Michael Rape
Processive ubiquitin chain formation by the anaphase-promoting complex.
Seminars in cell & developmental biology 2011;22(6):544-50.
2011: Adam Williamson; Xining Zhu; Sudeep Banerjee; Anthony T Iavarone; Isabelle Philipp; Michael Rape
Regulation of ubiquitin chain initiation to control the timing of substrate degradation.
Molecular cell 2011;42(6):744-57.
2011: Mark P A Luna-Vargas; Alex C Faesen; Willem J van Dijk; Michael Rape; Alexander Fish; Titia K Sixma
Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain.
EMBO reports 2011;12(4):365-72.
2011: Katherine E Wickliffe; Sonja Lorenz; David E Wemmer; John Kuriyan; Michael Rape
The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2.
Cell 2011;144(5):769-81.
2011: Ling Song; Michael Rape
Substrate-specific regulation of ubiquitination by the anaphase-promoting complex.
Cell cycle (Georgetown, Tex.) 2011;10(1):52-6.
2010: Marissa L Matsumoto; Katherine E Wickliffe; Ken C Dong; Christine Yu; Ivan Bosanac; Daisy Bustos; Lilian Phu; Donald S Kirkpatrick; Sarah G Hymowitz; Michael Rape; Robert F Kelley; Vishva M Dixit
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody.
Molecular cell 2010;39(3):477-84.
2010: Eun Joo Song; Shannon L Werner; Jakob Neubauer; Frank Stegmeier; Julie Aspden; Donald C Rio; J Wade Harper; Stephen J Elledge; Marc W Kirschner; Michael Rape
The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.
Genes & development 2010;24(13):1434-47.
2010: Ling Song; Michael Rape
Regulated degradation of spindle assembly factors by the anaphase-promoting complex.
Molecular cell 2010;38(3):369-82.
2010: Michael Rape
Assembly of k11-linked ubiquitin chains by the anaphase-promoting complex.
Sub-cellular biochemistry 2010;54():107-15.
2009: Yihong Ye; Michael Rape
Building ubiquitin chains: E2 enzymes at work.
Nature reviews. Molecular cell biology 2009;10(11):755-64.
2009: Adam Williamson; Katherine E Wickliffe; Barbara G Mellone; Ling Song; Gary Karpen; Michael Rape
Identification of a physiological E2 module for the human anaphase-promoting complex.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18213-8.
2009: Michael Rape
Ubiquitin, infinitely seductive: symposium on the many faces of ubiquitin.
EMBO reports 2009;10(6):558-62.
2009: Katherine Wickliffe; Adam Williamson; Lingyan Jin; Michael Rape
The multiple layers of ubiquitin-dependent cell cycle control.
Chemical reviews 2009;109(4):1537-48.
2009: Michael Rape
A set of surgical chain saws.
The EMBO journal 2009;28(6):615-6.
2009: Adam Williamson; Lingyan Jin; Michael Rape
Preparation of synchronized human cell extracts to study ubiquitination and degradation.
Methods in molecular biology (Clifton, N.J.) 2009;545():301-12.
2008: Lingyan Jin; Adam Williamson; Sudeep Banerjee; Isabelle Philipp; Michael Rape
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex.
Cell 2008;133(4):653-65.
2008: Ling Song; Michael Rape
Reverse the curse--the role of deubiquitination in cell cycle control.
Current opinion in cell biology 2008;20(2):156-63.
2007: Michael Rape
Cell cycle: on-time delivery of Plk1 during cytokinesis.
Current biology : CB 2007;17(13):R506-8.
2007: S K Reddy; Michael Rape; W A Margansky; Marc W Kirschner
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.
Nature 2007;446(7138):921-5.
2007: Frank Stegmeier; Michael Rape; Viji M Draviam; Grzegorz Nalepa; Mathew E Sowa; Xiaolu L Ang; E Robert McDonald; Mamie Z Li; Gregory J Hannon; Peter K Sorger; Marc W Kirschner; J Wade Harper; Stephen J Elledge
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Nature 2007;446(7138):876-81.
2007: Ulrich K Binné; Marie K Classon; Frederick A Dick; Wenyi Wei; Michael Rape; William G Kaelin; Anders M Näär; Nicholas J Dyson
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.
Nature cell biology 2007;9(2):225-32.
2006: Michael Rape; Sashank K Reddy; Marc W Kirschner
The processivity of multiubiquitination by the APC determines the order of substrate degradation.
Cell 2006;124(1):89-103.
2005: Judith A Jebanathirajah; Jason L Pittman; Bruce A Thomson; Bogdan A Budnik; Parminder Kaur; Michael Rape; Marc Kirschner; Catherine E Costello; Peter B O'Connor
Characterization of a new qQq-FTICR mass spectrometer for post-translational modification analysis and top-down tandem mass spectrometry of whole proteins.
Journal of the American Society for Mass Spectrometry 2005;16(12):1985-99.
2005: Holger Richly; Michael Rape; Sigurd Braun; Sebastian Rumpf; Carsten Hoege; Stefan Jentsch
A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting.
Cell 2005;120(1):73-84.
2005: Nagi Ayad; Susannah Rankin; Danny Ooi; Michael Rape; Marc W Kirschner
Identification of ubiquitin ligase substrates by in vitro expression cloning.
Methods in enzymology 2005;399():404-14.
2004: Michael Rape; Marc W Kirschner
Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.
Nature 2004;432(7017):588-95.
2004: Michael Rape; Stefan Jentsch
Productive RUPture: activation of transcription factors by proteasomal processing.
Biochimica et biophysica acta 2004;1695(1-3):209-13.
2002: Michael Rape; Stefan Jentsch
Taking a bite: proteasomal protein processing.
Nature cell biology 2002;4(5):E113-6.
2002: Sigurd Braun; Kai Matuschewski; Michael Rape; Sven Thoms; Stefan Jentsch
Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates.
The EMBO journal 2002;21(4):615-21.
2001: Michael Rape; T Hoppe; Ingo H Gorr; M Kalocay; Holger Richly; Stefan Jentsch
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone.
Cell 2001;107(5):667-77.
2001: T Hoppe; Michael Rape; Stefan Jentsch
Membrane-bound transcription factors: regulated release by RIP or RUP.
Current opinion in cell biology 2001;13(3):344-8.
2000: T Hoppe; Kai Matuschewski; Michael Rape; S Schlenker; HD Ulrich; Stefan Jentsch
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.
Cell 2000;102(5):577-86.