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Graça Raposo

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Brenda Watt; Graça Raposo; Guillaume van Niel; Michael S Marks
PMEL: a pigment cell-specific model for functional amyloid formation.
Graça Raposo; Willem Stoorvogel
Extracellular vesicles: exosomes, microvesicles, and friends.
Anand Sitaram; Elena V Sviderskaya; Danièle Tenza; Christopher S Wood; Dorothy C Bennett; Juan S Bonifacino; Rittik Chaudhuri; Wilfredo De Jesus-Rojas; Megan K Dennis; Graça Raposo; Subba Rao Gangi Setty; Michael S Marks
Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.

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All Publications

2013: Brenda Watt; Graça Raposo; Guillaume van Niel; Michael S Marks
PMEL: a pigment cell-specific model for functional amyloid formation.
Pigment cell & melanoma research 2013;26(3):300-15.
2013: Graça Raposo; Willem Stoorvogel
Extracellular vesicles: exosomes, microvesicles, and friends.
The Journal of cell biology 2013;200(4):373-83.
2012: Anand Sitaram; Elena V Sviderskaya; Danièle Tenza; Christopher S Wood; Dorothy C Bennett; Juan S Bonifacino; Rittik Chaudhuri; Wilfredo De Jesus-Rojas; Megan K Dennis; Graça Raposo; Subba Rao Gangi Setty; Michael S Marks
Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.
Molecular biology of the cell 2012;23(16):3178-92.
2012: Ronghua Meng; Mortimer Poncz; Graça Raposo; Anand Sitaram; Yuhuan Wang; Mitchell J Weiss; Yu Yao; Zhe Zhang; Dawn C Harper; Harry F G Heijnen; Wei Li; Michael S Marks
SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models.
Blood 2012;120(2):404-14.
2012: Zoi Erpapazoglou; Francesca Giordano; Manel Dhaoui; Sébastien Léon; Muriel Mari; Marina Pantazopoulou; Graça Raposo; Fulvio Reggiori; Rosine Haguenauer-Tsapis
A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting.
Molecular biology of the cell 2012;23(11):2170-83.
2012: Gaelle Boncompain; Helene de Forges; Severine Divoux; Nelly Gareil; Florence Jollivet; Lynda Latreche; Aurianne Lescure; Valentina Mercanti; Graça Raposo; Franck Perez
Synchronization of secretory protein traffic in populations of cells.
Nature methods 2012;9(5):493-8.
2012: Sylvain Loubéry; Daniel Louvard; Graça Raposo; Cédric Delevoye; Evelyne Coudrier
Myosin VI regulates actin dynamics and melanosome biogenesis.
Traffic (Copenhagen, Denmark) 2012;13(5):665-80.
2011: Angélique Bobrie; Marina Colombo; Graça Raposo; Clotilde Théry
Exosome secretion: molecular mechanisms and roles in immune responses.
Traffic (Copenhagen, Denmark) 2011;12(12):1659-68.
2011: Guillaume van Niel; Stéphanie Charrin; Michael S Marks; Leila Rochin; Maryse Romao; Eric Rubinstein; Paul Saftig; Sabrina Simoes; Graça Raposo
The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis.
Developmental cell 2011;21(4):708-21.
2011: Brenda Watt; Graça Raposo; Danièle Tenza; Leif Andersson; Susanne Kerje; Mark A Lemmon; Michael S Marks
Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic.
PLoS genetics 2011;7(9):e1002286.
2011: Anders R Hellström; Shosuke Ito; Susanne Kerje; Klas Kullander; Jimmy Larsson; Paula Mannström; Michael S Marks; Kristina Narfström; Graça Raposo; Danièle Tenza; Mats Ulfendahl; Kazumasa Wakamatsu; Brenda Watt; Björn Ekesten; Shahrzad Shirazi Fard; Finn Hallböök; Leif Andersson
Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation.
PLoS genetics 2011;7(9):e1002285.
2011: Francesca Giordano; Sabrina Simoes; Graça Raposo
The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(29):11906-11.
2011: Claudia G Almeida; Daniel Louvard; Graça Raposo; Danièle Tenza; Ayako Yamada; Evelyne Coudrier
Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network.
Nature cell biology 2011;13(7):779-89.
2011: Delphine Gogendeau; Ilse Hurbain; Graça Raposo; Jean Cohen; France Koll; Renata Basto
Sas-4 proteins are required during basal body duplication in Paramecium.
Molecular biology of the cell 2011;22(7):1035-44.
2011: Bidisha Sinha; Darius Köster; Richard Ruez; Pauline Gonnord; Michele Bastiani; Daniel Abankwa; Radu V Stan; Gillian Butler-Browne; Benoit Vedie; Ludger Johannes; Nobuhiro Morone; Robert G Parton; Graça Raposo; Pierre Sens; Christophe Lamaze; Pierre Nassoy
Cells respond to mechanical stress by rapid disassembly of caveolae.
Cell 2011;144(3):402-13.
2011: Cédric Delevoye; Francesca Giordano; Guillaume van Niel; Graça Raposo
[Biogenesis of melanosomes - the chessboard of pigmentation].
Médecine sciences : M/S 2011;27(2):153-62.
2011: Dafne Chirivino; Laurence Del Maestro; Etienne FORMSTECHER; Philippe Hupé; Graça Raposo; Daniel Louvard; Monique Arpin
The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.
Molecular biology of the cell 2011;22(3):375-85.
2010: F Javier Pérez-Victoria; Christina Schindler; Javier G Magadán; Gonzalo Mardones; Cédric Delevoye; Maryse Romao; Graça Raposo; Juan Bonifacino
Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex.
Molecular biology of the cell 2010;21(19):3386-95.
2010: Bahne Stechmann; Siau-Kun Bai; Emilie Gobbo; Roman Lopez; Goulven Merer; Suzy Pinchard; Laetitia Panigai; Danièle Tenza; Graça Raposo; Bruno Beaumelle; Didier Sauvaire; Daniel Gillet; Ludger Johannes; Julien Barbier
Inhibition of retrograde transport protects mice from lethal ricin challenge.
Cell 2010;141(2):231-42.
2010: Matias Ostrowski; Nuno B Carmo; Sophie Krumeich; Isabelle Fanget; Graça Raposo; Ariel Savina; Catarina F Moita; Kristine Schauer; Alistair N Hume; Rui P Freitas; Bruno Goud; Philippe Benaroch; Nir Hacohen; Mitsunori Fukuda; Claire Desnos; Miguel C Seabra; François Darchen; Sebastian Amigorena; Luis F Moita; Clotilde Thery
Rab27a and Rab27b control different steps of the exosome secretion pathway.
Nature cell biology 2010;12(1):19-30; sup pp 1-13.
2009: Brenda Watt; Guillaume van Niel; Douglas M Fowler; Ilse Hurbain; Kelvin C Luk; Steven E Stayrook; Mark A Lemmon; Graça Raposo; James Shorter; Jeffery W Kelly; Michael S Marks
N-terminal domains elicit formation of functional Pmel17 amyloid fibrils.
The Journal of biological chemistry 2009;284(51):35543-55.
2009: Vincent Popoff; Gonzalo Mardones; Siau-Kun Bai; Valérie Chambon; Danièle Tenza; Patricia V Burgos; Anbing Shi; Philippe Benaroch; Sylvie Urbé; Christophe Lamaze; Barth D Grant; Graça Raposo; Ludger Johannes
Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes.
Traffic (Copenhagen, Denmark) 2009;10(12):1868-80.
2009: Francesca Giordano; Ciro Bonetti; Enrico M Surace; Valeria Marigo; Graça Raposo
The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition.
Human molecular genetics 2009;18(23):4530-45.
2009: Cédric Delevoye; Ilse Hurbain; Danièle Tenza; Jean-Baptiste Sibarita; Stéphanie Uzan-Gafsou; Hiroshi Ohno; Willie J.C. Geerts; Arie J Verkleij; Jean Salamero; Michael S Marks; Graça Raposo
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis.
The Journal of cell biology 2009;187(2):247-64.
2009: Sonja Buschow; Esther N M Nolte-'t Hoen; Guillaume van Niel; Maaike Sabine Pols; Toine Ten Broeke; Marjolein Lauwen; Ferry Ossendorp; Cornelis J M Melief; Graça Raposo; Richard Wubbolts; Marca H M Wauben; Willem Stoorvogel
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways.
Traffic (Copenhagen, Denmark) 2009;10(10):1528-42.
2009: Steven T Truschel; Sabrina Simoes; Subba Rao Gangi Setty; Dawn C Harper; Danièle Tenza; Penelope C Thomas; Kathryn E Herman; Sara D Sackett; David C Cowan; Alexander C Theos; Graça Raposo; Michael S Marks
ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane.
Traffic (Copenhagen, Denmark) 2009;10(9):1318-36.
2009: Floria Lizárraga; Renaud Poincloux; Maryse Romao; Guillaume Montagnac; gaelle le dez; Isabelle Bonne; Guillem Rigaill; Graça Raposo; Philippe Chavrier
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells.
Cancer research 2009;69(7):2792-800.
2009: Guillaume Montagnac; Jean-Baptiste Sibarita; Sylvain Loubéry; Laurent Daviet; Maryse Romao; Graça Raposo; Philippe Chavrier
ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis.
Current biology : CB 2009;19(3):184-95.
2009: Ariane Dimitrov; Vincent Paupe; Charles Gueudry; Jean-Baptiste Sibarita; Graça Raposo; Ole Vielemeyer; Thierry Gilbert; Zsolt Csaba; Tania Attie-Bitach; Valérie Cormier-Daire; Pierre Gressens; Pierre Rustin; Franck Perez; Vincent El Ghouzzi
The gene responsible for Dyggve-Melchior-Clausen syndrome encodes a novel peripheral membrane protein dynamically associated with the Golgi apparatus.
Human molecular genetics 2009;18(3):440-53.
2008: Raul Rojas; Thijs van Vlijmen; Gonzalo Mardones; Yogikala Prabhu; Adriana Rojas; shabaz mohammed; Albert J R Heck; Graça Raposo; Peter van der Sluijs; Juan Bonifacino
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.
The Journal of cell biology 2008;183(3):513-26.
2008: Sandrine Alais; Sabrina Simoes; Dominique Baas; Sylvain Lehmann; Graça Raposo; Jean-Luc Darlix; Pascal LEBLANC
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles.
Biology of the cell / under the auspices of the European Cell Biology Organization 2008;100(10):603-15.
2008: Subba Rao Gangi Setty; Danièle Tenza; Elena V Sviderskaya; Dorothy C Bennett; Graça Raposo; Michael S Marks
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes.
Nature 2008;454(7208):1142-6.
2008: Graça Raposo; Harald Stenmark
Membranes and organelles.
Current opinion in cell biology 2008;20(4):357-9.
2008: Dawn C Harper; Alexander C Theos; Kathryn E Herman; Danièle Tenza; Graça Raposo; Michael S Marks
Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes.
The Journal of biological chemistry 2008;283(4):2307-22.
2007: Virginie Braun; Chantal Deschamps; Graça Raposo; Philippe Benaroch; Alexandre Benmerah; Philippe Chavrier; Florence Niedergang
AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis.
Molecular biology of the cell 2007;18(12):4921-31.
2007: Winfried Römer; Ludwig Berland; Valérie Chambon; Katharina Gaus; Barbara Windschiegl; Danièle Tenza; Mohamed Aly; Vincent Fraisier; Jean-Claude Florent; David Perrais; Christophe Lamaze; Graça Raposo; Claudia Steinem; Pierre Sens; Patricia Bassereau; Ludger Johannes
Shiga toxin induces tubular membrane invaginations for its uptake into cells.
Nature 2007;450(7170):670-5.
2007: Florence Jollivet; Graça Raposo; Ariane Dimitrov; Rachid Sougrat; Bruno Goud; Franck Perez
Analysis of de novo Golgi complex formation after enzyme-based inactivation.
Molecular biology of the cell 2007;18(11):4637-47.
2007: Graça Raposo; Michael S Marks
Melanosomes--dark organelles enlighten endosomal membrane transport.
Nature reviews. Molecular cell biology 2007;8(10):786-97.
2007: Stéphanie Miserey-Lenkei; François Waharte; Annick Boulet; Marie-Hélène Cuif; Danièle Tenza; Ahmed El Marjou; Graça Raposo; Jean Salamero; Laurent Héliot; Bruno Goud; Solange Monier
Rab6-interacting protein 1 links Rab6 and Rab11 function.
Traffic (Copenhagen, Denmark) 2007;8(10):1385-403.
2007: Graça Raposo; Michael S Marks; Daniel F Cutler
Lysosome-related organelles: driving post-Golgi compartments into specialisation.
Current opinion in cell biology 2007;19(4):394-401.
2007: Hans J Kueng; Victoria M Leb; Daniela Haiderer; Graça Raposo; Clotilde Thery; Sophia Derdak; Klaus G Schmetterer; Alina Neunkirchner; Christian Sillaber; Brian Seed; Winfried F Pickl
General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines.
Journal of virology 2007;81(16):8666-76.
2007: Kouichi Mizuno; Tanya Tolmachova; Dmitry S Ushakov; Maryse Romao; Magnus Abrink; Michael A Ferenczi; Graça Raposo; Miguel C Seabra
Rab27b regulates mast cell granule dynamics and secretion.
Traffic (Copenhagen, Denmark) 2007;8(7):883-92.
2007: Vincent Popoff; Gonzalo Mardones; Danièle Tenza; Raúl Rojas; Christophe Lamaze; Juan Bonifacino; Graça Raposo; Ludger Johannes
The retromer complex and clathrin define an early endosomal retrograde exit site.
Journal of cell science 2007;120(Pt 12):2022-31.
2007: Julia Mallegol; Guillaume van Niel; Corinne Lebreton; yves lepelletier; Céline Candalh; Christophe Dugave; Joan K Heath; Graça Raposo; Nadine Cerf-Bensussan; Martine Heyman
T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells.
Gastroenterology 2007;132(5):1866-76.
2007: Véronique Proux-Gillardeaux; Graça Raposo; Theano Irinopoulou; Thierry Galli
Expression of the Longin domain of TI-VAMP impairs lysosomal secretion and epithelial cell migration.
Biology of the cell / under the auspices of the European Cell Biology Organization 2007;99(5):261-71.
2007: Carolina Jancic; Ariel Savina; Christina Wasmeier; Tanya Tolmachova; Jamel El Benna; Pham My-Chan Dang; Steve Pascolo; Marie-Anne Gougerot-Pocidalo; Graça Raposo; Miguel C Seabra; Sebastian Amigorena
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes.
Nature cell biology 2007;9(4):367-78.
2007: Fulvia Vascotto; Danielle Lankar; Gabrielle Faure-André; P VARGAS; Jheimmy Diaz; Delphine Le Roux; Maria-Isabel Yuseff; Jean-Baptiste Sibarita; Marianne Boes; Graça Raposo; Evelyne Mougneau; Nicolas Glaichenhaus; Christian Bonnerot; Bénédicte Manoury; Ana-Maria Lennon-Duménil
The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation.
The Journal of cell biology 2007;176(7):1007-19.
2007: Mickaël Ménager; Gaël Ménasché; Maryse Romao; Perrine Knapnougel; Chen-Hsuan Ho; Mériem Garfa; Graça Raposo; Jérôme Feldmann; Alain Fischer; Geneviève de Saint Basile
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4.
Nature immunology 2007;8(3):257-67.
2007: Subba Rao Gangi Setty; Danièle Tenza; Steven T Truschel; Evelyn Chou; Elena V Sviderskaya; Alexander C Theos; M Lynn Lamoreux; Santiago M Di Pietro; Marta Starcevic; Dorothy C Bennett; Esteban C Dell'Angelica; Graça Raposo; Michael S Marks
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles.
Molecular biology of the cell 2007;18(3):768-80.
2006: Guillaume van Niel; Richard Wubbolts; Toine Ten Broeke; Sonja Buschow; Ferry Ossendorp; Cornelis J Melief; Graça Raposo; Bas W van Balkom; Willem Stoorvogel
Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination.
Immunity 2006;25(6):885-94.
2006: Anita Scheuber; Rachel Rudge; Lydia Danglot; Graça Raposo; Thomas Binz; Jean Christophe Poncer; Thierry Galli
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16562-7.
2006: Christina Wasmeier; Maryse Romao; Lynn Plowright; Dorothy C Bennett; Graça Raposo; Miguel C Seabra
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes.
The Journal of cell biology 2006;175(2):271-81.
2006: Santiago M Di Pietro; Juan M Falcón-Pérez; Danièle Tenza; Subba Rao Gangi Setty; Michael S Marks; Graça Raposo; Esteban C Dell'Angelica
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes.
Molecular biology of the cell 2006;17(9):4027-38.
2006: Alexander C Theos; Joanne F Berson; Sarah C Theos; Kathryn E Herman; Dawn C Harper; Danièle Tenza; Elena V Sviderskaya; M Lynn Lamoreux; Dorothy C Bennett; Graça Raposo; Michael S Marks
Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17.
Molecular biology of the cell 2006;17(8):3598-612.
2006: Pascale Rialland; Danielle Lankar; Graça Raposo; Christian Bonnerot; Pascale Hubert
BCR-bound antigen is targeted to exosomes in human follicular lymphoma B-cells.
Biology of the cell / under the auspices of the European Cell Biology Organization 2006;98(8):491-501.
2006: Ariel Savina; Carolina Jancic; Stéphanie Hugues; Pierre Guermonprez; P VARGAS; Ivan C Moura; Ana-Maria Lennon-Duménil; Miguel C Seabra; Graça Raposo; Sebastian Amigorena
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells.
Cell 2006;126(1):205-18.
2006: Guillaume van Niel; Isabel Porto-Carreiro; Sabrina Simoes; Graça Raposo
Exosomes: a common pathway for a specialized function.
Journal of biochemistry 2006;140(1):13-21.
2006: Carmen Bracho; Irene Dunia; Mirtha Romano; Graça Raposo; Mercedes De La Rosa; Ennio-Lucio Benedetti; Hilda A Pérez
Caveolins and flotillin-2 are present in the blood stages of Plasmodium vivax.
Parasitology research 2006;99(2):153-9.
2006: Pascal LEBLANC; Sandrine Alais; Isabel Porto-Carreiro; Sylvain Lehmann; Jacques Grassi; Graça Raposo; Jean-Luc Darlix
Retrovirus infection strongly enhances scrapie infectivity release in cell culture.
The EMBO journal 2006;25(12):2674-85.
2006: Clotilde Théry; Sebastian Amigorena; Graça Raposo; Aled Clayton
Isolation and characterization of exosomes from cell culture supernatants and biological fluids.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2006;Chapter 3():Unit 3.22.
2006: Alexander C Theos; Steven T Truschel; Danièle Tenza; Ilse Hurbain; Dawn C Harper; Joanne F Berson; Penelope C Thomas; Graça Raposo; Michael S Marks
A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis.
Developmental cell 2006;10(3):343-54.
2006: Julien Taieb; Nathalie Chaput; Cédric Ménard; Lionel Apetoh; Evelyn Ullrich; Mathieu Bonmort; Marie Péquignot; Noelia Casares; Magali Terme; Caroline Flament; Paule Opolon; Yann Lecluse; Didier Métivier; Elena Tomasello; Eric Vivier; François Ghiringhelli; François Martin; David Klatzmann; Thierry Poynard; Thomas Tursz; Graça Raposo; Hideo Yagita; Bernard Ryffel; Guido Kroemer; Laurence Zitvogel
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2006: Soraya Abouzahr; Georges Bismuth; Catherine Gaudin; Oliver Caroll; Peter van Endert; Abdelali JALIL; Jean Dausset; Isabelle Vergnon; Catherine Richon; Audrey Kauffmann; Jérôme Galon; Graça Raposo; Fathia Mami-Chouaib; Salem Chouaib
Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1428-33.
2005: Alexander C Theos; Danièle Tenza; José A Martina; Ilse Hurbain; Andrew A Peden; Elena V Sviderskaya; Abigail Stewart; Margaret S Robinson; Dorothy C Bennett; Daniel F Cutler; Juan Bonifacino; Michael S Marks; Graça Raposo
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes.
Molecular biology of the cell 2005;16(11):5356-72.
2005: Laura Salas-Cortes; Fei Ye; Danièle Tenza; Claire Wilhelm; Alexander C Theos; Daniel Louvard; Graça Raposo; Evelyne Coudrier
Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes.
Journal of cell science 2005;118(Pt 20):4823-32.
2005: Ilaria Potolicchio; Sriram Chitta; Xiaonan Xu; Dora Fonseca; Giovanna Crisi; Vaclav Horejsi; Jack L Strominger; Lawrence J Stern; Graça Raposo; Laura Santambrogio
Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):4935-47.
2005: Laura Santambrogio; Ilaria Potolicchio; Shawn P Fessler; Siew Heng Wong; Graça Raposo; Jack L Strominger
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells.
Nature immunology 2005;6(10):1020-8.
2005: Alexander C Theos; Steven T Truschel; Graça Raposo; Michael S Marks
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2005;18(5):322-36.
2005: Isabel Porto-Carreiro; Benoît Février; Sophie Paquet; Didier Vilette; Graça Raposo
Prions and exosomes: from PrPc trafficking to PrPsc propagation.
Blood cells, molecules & diseases 2005;35(2):143-8.
2005: Marie-Pierre Caby; Danielle Lankar; Claude Vincendeau-Scherrer; Graça Raposo; Christian Bonnerot
Exosomal-like vesicles are present in human blood plasma.
International immunology 2005;17(7):879-87.
2005: Elodie Segura; Carole Nicco; Bérangère Lombard; Philippe Véron; Graça Raposo; Frédéric Batteux; Sebastian Amigorena; Clotilde Théry
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming.
Blood 2005;106(1):216-23.
2005: cedric BROSSARD; Vincent Feuillet; Alain Schmitt; Clotilde Randriamampita; Maryse Romao; Graça Raposo; Alain Trautmann
Multifocal structure of the T cell - dendritic cell synapse.
European journal of immunology 2005;35(6):1741-53.
2005: Martin Baumgartner; Marie Chaussepied; Graça Raposo; Bruno Goud; Gordon Langsley
Accelerated recycling of transferrin receptor in Theileria-transformed B cells.
Cellular microbiology 2005;7(5):637-44.
2005: Benoît Février; Hubert Laude; Graça Raposo; Didier Vilette
[Exosomes: carriers of prions?].
Médecine sciences : M/S 2005;21(2):132-3.
2005: Benoît Février; Didier Vilette; Hubert Laude; Graça Raposo
Exosomes: a bubble ride for prions?
Traffic (Copenhagen, Denmark) 2005;6(1):10-7.
2004: Virginie Braun; Vincent Fraisier; Graça Raposo; Ilse Hurbain; Jean-Baptiste Sibarita; Philippe Chavrier; Thierry Galli; Florence Niedergang
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages.
The EMBO journal 2004;23(21):4166-76.
2004: Nathalie Planque; Graça Raposo; Laurence Leconte; Oceane Anezo; Patrick Martin; Simon Saule
Microphthalmia transcription factor induces both retinal pigmented epithelium and neural crest melanocytes from neuroretina cells.
The Journal of biological chemistry 2004;279(40):41911-7.
2004: Franck Coumailleau; Vincent Das; Andrés Alcover; Graça Raposo; Sandrine Vandormael-Pournin; Stéphanie Le Bras; Patricia Baldacci; Alice Dautry-Varsat; Charles Babinet; Michel Cohen-Tannoudji
Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.
Molecular biology of the cell 2004;15(10):4444-56.
2004: Benoît Février; Graça Raposo
Exosomes: endosomal-derived vesicles shipping extracellular messages.
Current opinion in cell biology 2004;16(4):415-21.
2004: Annegret Pelchen-Matthews; Graça Raposo; Mark Marsh
Endosomes, exosomes and Trojan viruses.
Trends in microbiology 2004;12(7):310-6.
2004: Eliana Real; Andrew Kaiser; Graça Raposo; Ali Amara; Alessandra Nardin; Alain Trautmann; Emmanuel Donnadieu
Immature dendritic cells (DCs) use chemokines and intercellular adhesion molecule (ICAM)-1, but not DC-specific ICAM-3-grabbing nonintegrin, to stimulate CD4+ T cells in the absence of exogenous antigen.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):50-60.
2004: Benoit Fevrier; Didier Vilette; Fabienne Archer; Damarys Loew; Wolfgang Faigle; Michel Vidal; Hubert Laude; Graça Raposo
Cells release prions in association with exosomes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9683-8.
2004: Megan C King; Graça Raposo; Mark A Lemmon
Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(24):8957-62.
2004: Fabrice André; Nathalie Chaput; Noël Emile Célestin Schartz; Caroline Flament; Nathalie Aubert; Jacky Bernard; François Lemonnier; Graça Raposo; Bernard Escudier; Di-Hwei Hsu; Thomas Tursz; Sebastian Amigorena; Eric Angevin; Laurence Zitvogel
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2126-36.
2003: aude de gassart; Charles Geminard; Benoit Fevrier; Graça Raposo; Michel Vidal
Lipid raft-associated protein sorting in exosomes.
Blood 2003;102(13):4336-44.
2003: Magali Prigent; Thierry Dubois; Graça Raposo; Valérie Derrien; Danièle Tenza; Carine Rossé; Jacques Camonis; Philippe Chavrier
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector.
The Journal of cell biology 2003;163(5):1111-21.
2003: Pamela Stumptner-Cuvelette; Mabel Jouve; Julie Helft; Marc Dugast; Anne-Sophie Glouzman; Karin Jooss; Graça Raposo; Philippe Benaroch
Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase.
Molecular biology of the cell 2003;14(12):4857-70.
2003: Jérôme Feldmann; Isabelle Callebaut; Graça Raposo; Stéphanie Certain; Delphine Bacq; Cécile Dumont; Nathalie Lambert; Marie Ouachée-Chardin; Gaëlle Chedeville; Hannah Tamary; Véronique Minard-Colin; Etienne Vilmer; Stéphane Blanche; Françoise Le Deist; Alain Fischer; Geneviève de Saint Basile
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).
Cell 2003;115(4):461-73.
2003: Claire Desnos; Jean-Sébastien SCHONN; Sébastien Huet; Viet Samuel Tran; Aziz El-Amraoui; Graça Raposo; Isabelle Fanget; Catherine Chapuis; Gaël Ménasché; Geneviève de Saint Basile; Christine Petit; Sophie Cribier; Jean-Pierre Henry; François Darchen
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites.
The Journal of cell biology 2003;163(3):559-70.
2003: Sonia Martinez-Arca; Rachel Rudge; Marcella Vacca; Graça Raposo; Jacques Camonis; Véronique Proux-Gillardeaux; Laurent Daviet; Etienne FORMSTECHER; Alexandre Hamburger; Francesco Filippini; Maurizio D'Esposito; Thierry Galli
A dual mechanism controlling the localization and function of exocytic v-SNAREs.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):9011-6.
2003: Florence Niedergang; Emma Colucci-Guyon; Thierry Dubois; Graça Raposo; Philippe Chavrier
ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages.
The Journal of cell biology 2003;161(6):1143-50.
2003: Joanne F Berson; Alexander C Theos; Dawn C Harper; Danièle Tenza; Graça Raposo; Michael S Marks
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis.
The Journal of cell biology 2003;161(3):521-33.
2003: Gaelle Benais-Pont; Anu Punn; Catalina Flores-Maldonado; judith eckert; Graça Raposo; Tom P Fleming; Marcelino Cereijido; Maria S Balda; Karl Matter
Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability.
The Journal of cell biology 2003;160(5):729-40.
2003: Marie Granboulan; Danielle Lankar; Graça Raposo; Christian Bonnerot; Claire Hivroz
Phosphoinositide 3-kinase activation by Igbeta controls de novo formation of an antigen-processing compartment.
The Journal of biological chemistry 2003;278(6):4331-8.
2003: Michael S Marks; Alexander C Theos; Graça Raposo
Melanosomes and MHC class II antigen-processing compartments: a tinted view of intracellular trafficking and immunity.
Immunologic research 2003;27(2-3):409-26.
2002: Fabrice André; Noël Emile Célestin Schartz; Nathalie Chaput; Caroline Flament; Graça Raposo; Sebastian Amigorena; Eric Angevin; Laurence Zitvogel
Tumor-derived exosomes: a new source of tumor rejection antigens.
Vaccine 2002;20 Suppl 4():A28-31.
2002: Graça Raposo; Benoit Fevrier; Willem Stoorvogel; Michael S Marks
Lysosome-related organelles: a view from immunity and pigmentation.
Cell structure and function 2002;27(6):443-56.
2002: Aura Muntasell; Montserrat Carrascal; Laurence Serradell; Peter van Veelen Pv; Frank A W Verreck; Frits Koning; Graça Raposo; Joaquín Abián; Dolores Jaraquemada
HLA-DR4 molecules in neuroendocrine epithelial cells associate to a heterogeneous repertoire of cytoplasmic and surface self peptides.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5052-60.
2002: Graça Raposo; Marilyn Moore; Donald Innes; Richtje Leijendekker; Andrew Leigh-Brown; Philippe Benaroch; Hans J Geuze
Human macrophages accumulate HIV-1 particles in MHC II compartments.
Traffic (Copenhagen, Denmark) 2002;3(10):718-29.
2002: Fabrice Andre; Noël Emile Célestin Schartz; Mojgan Movassagh; Caroline Flament; Patricia Pautier; Philippe Morice; Christophe Pomel; Catherine Lhomme; Bernard Escudier; Thierry Le Chevalier; Thomas Tursz; Sebastian Amigorena; Graça Raposo; Eric Angevin; Laurence Zitvogel
Malignant effusions and immunogenic tumour-derived exosomes.
Lancet 2002;360(9329):295-305.
2002: Hélène Vincent-Schneider; Pamela Stumptner-Cuvelette; Danielle Lankar; Sabine Pain; Graça Raposo; Philippe Benaroch; Christian Bonnerot
Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells.
International immunology 2002;14(7):713-22.
2002: Willem Stoorvogel; Monique J Kleijmeer; Hans J Geuze; Graça Raposo
The biogenesis and functions of exosomes.
Traffic (Copenhagen, Denmark) 2002;3(5):321-30.
2002: Graça Raposo; Michael S Marks
The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis.
Traffic (Copenhagen, Denmark) 2002;3(4):237-48.
2002: Nicolas Blanchard; Danielle Lankar; Florence Faure; Armelle Regnault; Céline Dumont; Graça Raposo; Claire Hivroz
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3235-41.
2002: Danielle Lankar; Hélène Vincent-Schneider; Volker Briken; Takeaki Yokozeki; Graça Raposo; Christian Bonnerot
Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation.
The Journal of experimental medicine 2002;195(4):461-72.
2002: Ray Mc Dermott; Umit Ziylan; Danièle Spehner; Huguette Bausinger; Dan Lipsker; Mieke Mommaas; Jean-Pierre Cazenave; Graça Raposo; Bruno Goud; Henri de la Salle; Jean Salamero; Daniel Hanau
Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates.
Molecular biology of the cell 2002;13(1):317-35.
2001: Joanne F Berson; Dawn C Harper; Danièle Tenza; Graça Raposo; Michael S Marks
Pmel17 initiates premelanosome morphogenesis within multivesicular bodies.
Molecular biology of the cell 2001;12(11):3451-64.
2001: Pamela Stumptner-Cuvelette; S Morchoisne; Marc Dugast; S Le Gall; Graça Raposo; Olivier Schwartz; Philippe Benaroch
HIV-1 Nef impairs MHC class II antigen presentation and surface expression.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(21):12144-9.
2001: Guillaume van Niel; Graça Raposo; Céline Candalh; Muriel Boussac; R Hershberg; Nadine Cerf-Bensussan; Martine Heyman
Intestinal epithelial cells secrete exosome-like vesicles.
Gastroenterology 2001;121(2):337-49.
2001: Clotilde Théry; Muriel Boussac; Philippe Véron; Paola Ricciardi-Castagnoli; Graça Raposo; Jérôme Garin; Sebastian Amigorena
Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7309-18.
2001: J Wolfers; A Lozier; Graça Raposo; Armelle Regnault; Clotilde Théry; Carole Masurier; Caroline Flament; S Pouzieux; Florence Faure; Thomas Tursz; Eric Angevin; Sebastian Amigorena; Laurence Zitvogel
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.
Nature medicine 2001;7(3):297-303.
2001: C Baron; Graça Raposo; Susy M Scholl; Huguette Bausinger; Danièle Tenza; Alain Bohbot; Pierre Pouillart; Bruno Goud; Daniel Hanau; Jean Salamero
Modulation of MHC class II transport and lysosome distribution by macrophage-colony stimulating factor in human dendritic cells derived from monocytes.
Journal of cell science 2001;114(Pt 5):999-1010.
2001: Graça Raposo; Danièle Tenza; D M Murphy; Joanne F Berson; Michael S Marks
Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells.
The Journal of cell biology 2001;152(4):809-24.
2001: Fabrice Andre; M Andersen; J Wolfers; A Lozier; Graça Raposo; V Serra; C Ruegg; Caroline Flament; Eric Angevin; Sebastian Amigorena; Laurence Zitvogel
Exosomes in cancer immunotherapy: preclinical data.
Advances in experimental medicine and biology 2001;495():349-54.
2001: Hélène Vincent-Schneider; Clotilde Théry; D Mazzeo; Danièle Tenza; Graça Raposo; Christian Bonnerot
Secretory granules of mast cells accumulate mature and immature MHC class II molecules.
Journal of cell science 2001;114(Pt 2):323-34.
2000: L Erdtmann; Katy Janvier; Graça Raposo; Heather Craig; Philippe Benaroch; Clarisse Berlioz-Torrent; John C Guatelli; Richard Benarous; Serge Benichou
Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex.
Traffic (Copenhagen, Denmark) 2000;1(11):871-83.
2000: A Durrbach; Graça Raposo; Danièle Tenza; Daniel Louvard; Evelyne Coudrier
Truncated brush border myosin I affects membrane traffic in polarized epithelial cells.
Traffic (Copenhagen, Denmark) 2000;1(5):411-24.
2000: Geneviève Boulla; Clotilde Randriamampita; Graça Raposo; Alain Trautmann
Binding kinetics of soluble ligands to transmembrane proteins: comparing an optical biosensor and dynamic flow cytometry.
Cytometry 2000;40(1):76-80.
1999: Silvia Coco; Graça Raposo; S Martinez; JJ Fontaine; S Takamori; Ahmed Zahraoui; R Jahn; Michela Matteoli; Daniel Louvard; Thierry Galli
Subcellular localization of tetanus neurotoxin-insensitive vesicle-associated membrane protein (VAMP)/VAMP7 in neuronal cells: evidence for a novel membrane compartment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(22):9803-12.
1999: Clotilde Théry; Armelle Regnault; Jérôme Garin; J Wolfers; Laurence Zitvogel; Paola Ricciardi-Castagnoli; Graça Raposo; Sebastian Amigorena
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.
The Journal of cell biology 1999;147(3):599-610.
1999: Valerie Brachet; G Péhau-Arnaudet; Catherine Desaymard; Graça Raposo; Sebastian Amigorena
Early endosomes are required for major histocompatiblity complex class II transport to peptide-loading compartments.
Molecular biology of the cell 1999;10(9):2891-904.
1999: Laurence Zitvogel; Nadine C Fernandez; A Lozier; J Wolfers; Armelle Regnault; Graça Raposo; Sebastian Amigorena
Dendritic cells or their exosomes are effective biotherapies of cancer.
European journal of cancer (Oxford, England : 1990) 1999;35 Suppl 3():S36-8.
1999: Graça Raposo; M N Cordonnier; Danièle Tenza; B Menichi; A Dürrbach; Daniel Louvard; Evelyne Coudrier
Association of myosin I alpha with endosomes and lysosomes in mammalian cells.
Molecular biology of the cell 1999;10(5):1477-94.
1998: Thierry Galli; Ahmed Zahraoui; V V Vaidyanathan; Graça Raposo; Jianmin Tian; Michael Karin; H Niemann; Daniel Louvard
A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells.
Molecular biology of the cell 1998;9(6):1437-48.
1998: Wolfgang Faigle; Graça Raposo; Danièle Tenza; VM Pinet; Anne B Vogt; Harald Kropshofer; A Fischer; G de Saint-Basile; Sebastian Amigorena
Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome.
The Journal of cell biology 1998;141(5):1121-34.
1998: Laurence Zitvogel; Armelle Regnault; A Lozier; J Wolfers; Caroline Flament; Danièle Tenza; Paola Ricciardi-Castagnoli; Graça Raposo; Sebastian Amigorena
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes.
Nature medicine 1998;4(5):594-600.
1997: Graça Raposo; Danièle Tenza; S Mecheri; R Peronet; Christian Bonnerot; Catherine Desaymard
Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation.
Molecular biology of the cell 1997;8(12):2631-45.
1997: Valerie Brachet; Graça Raposo; Sebastian Amigorena; I Mellman
Ii chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes.
The Journal of cell biology 1997;137(1):51-65.