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Nina Bhardwaj

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Rachel Lubong Sabado; Nina Bhardwaj
Dendritic cell immunotherapy.
Patrick A Ott; Sonja Jimenez Baranda; Dusan Bogunovic; Davor Frleta; Trevor Henry; Olivier Manches; Nina Bhardwaj
Inhibition of both BRAF and MEK in BRAF(V600E) mutant melanoma restores compromised dendritic cell (DC) function while having differential direct effects on DC properties.
Meagan O'Brien; Olivier Manches; Nina Bhardwaj
Plasmacytoid dendritic cells in HIV infection.

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All Publications

2013: Rachel Lubong Sabado; Nina Bhardwaj
Dendritic cell immunotherapy.
Annals of the New York Academy of Sciences 2013;1284(1):31-45.
2013: Patrick A Ott; Sonja Jimenez Baranda; Dusan Bogunovic; Davor Frleta; Trevor Henry; Olivier Manches; Nina Bhardwaj
Inhibition of both BRAF and MEK in BRAF(V600E) mutant melanoma restores compromised dendritic cell (DC) function while having differential direct effects on DC properties.
Cancer immunology, immunotherapy : CII 2013;62(4):811-22.
2013: Meagan O'Brien; Olivier Manches; Nina Bhardwaj
Plasmacytoid dendritic cells in HIV infection.
Advances in experimental medicine and biology 2013;762():71-107.
2012: Elizabeth A Miller; Meagan P OʼBrien; Linda Rolnitzky; Rachel Sabado; Meredith R Spadaccia; Davor Frleta; Olivier Manches; Nina Bhardwaj
Plasma factors during chronic HIV-1 infection impair IL-12 secretion by myeloid dendritic cells via a virus-independent pathway.
Journal of acquired immune deficiency syndromes (1999) 2012;61(5):535-44.
2012: Sylvia Adams; Deborah Axelrod; Nina Bhardwaj; Luis Chiriboga; Silvia C Formenti; Judith D Goldberg; Tsivia Hochman; Lina Kozhaya; Leonard Liebes; Frank Martiniuk; Tze-Chiang Meng; Yelena Novik; Nicholas Shuman; James Speyer; Amy Tiersten; Derya Unutmaz; Sandra Demaria
Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(24):6748-57.
2012: Davor Frleta; Barton F Haynes; Benedikt M Kessler; Shaukat Ali Khan; Holger B Kramer; Carolyn E Ochoa; Andrea R Stacey; Persephone Borrow; Nina Bhardwaj
HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44.
The Journal of clinical investigation 2012;122(12):4685-97.
2012: Olivier Manches; Joël Plumas; Laurence Chaperot; Melissa Victoria Fernandez; Nina Bhardwaj
Activation of the noncanonical NF-κB pathway by HIV controls a dendritic cell immunoregulatory phenotype.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(35):14122-7.
2012: Michelle W Ma; Ratna C Medicherla; Iman Osman; Patrick A Ott; Anna Pavlick; Meng Qian; Yongzhao Shao; Richard L Shapiro; Eleazar Vega-Saenz de Miera; Russell S Berman; Nina Bhardwaj; Erica B Friedman; Farbod Darvishian
Immune response in melanoma: an in-depth analysis of the primary tumor and corresponding sentinel lymph node.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2012;25(7):1000-10.
2011: Avital Gaziel-Sovran; Douglas Hanniford; Nina Bhardwaj; Mary K Collins; John F Dankert; Farbod Darvishian; Raffaella Di Micco; Adrian Erlebacher; Robert S Kerbel; Lara K Mahal; Iman Osman; John F Rakus; Miguel F Segura; Shulian Shang; Yongzhao Shao; Eleazar Vega-Saenz de Miera; Jiri Zavadil; Eva Hernando
miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis.
Cancer cell 2011;20(1):104-18.
2011: Nicole Sunseri; Meagan O'Brien; Nina Bhardwaj; Nathaniel R Landau
Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells.
Journal of virology 2011;85(13):6263-74.
2011: Sonia Jimenez-Baranda; Benjamin Greenbaum; Olivier Manches; Jesse Handler; Raúl Rabadán; Arnold Levine; Nina Bhardwaj
Oligonucleotide motifs that disappear during the evolution of influenza virus in humans increase alpha interferon secretion by plasmacytoid dendritic cells.
Journal of virology 2011;85(8):3893-904.
2011: Emmanuelle Godefroy; Olivier Manches; Brigitte Dréno; Tsivia Hochman; Linda Rolnitzky; Nathalie Labarrière; Yannick Guilloux; Judith Goldberg; Francine Jotereau; Nina Bhardwaj
Matrix metalloproteinase-2 conditions human dendritic cells to prime inflammatory T(H)2 cells via an IL-12- and OX40L-dependent pathway.
Cancer cell 2011;19(3):333-46.
2011: Meagan O'Brien; Olivier Manches; Rachel Lubong Sabado; Sonia Jimenez Baranda; Yaming Wang; Isabelle Marie; Linda Rolnitzky; Martin Markowitz; David M Margolis; David Levy; Nina Bhardwaj
Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α-producing and partially matured phenotype.
The Journal of clinical investigation 2011;121(3):1088-101.
2010: Jonathan E Feig; Ines Pineda-Torra; Marie Sanson; Michelle N Bradley; Yuliya Vengrenyuk; Dusan Bogunovic; Emmanuel L Gautier; Daniel Rubinstein; Cynthia Hong; Jianhua Liu; Chaowei Wu; Nico van Rooijen; Nina Bhardwaj; Michael Garabedian; Peter Tontonoz; Edward A Fisher
LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression.
The Journal of clinical investigation 2010;120(12):4415-24.
2010: Rachel Lubong Sabado; Meagan O'Brien; Abhignya Subedi; Li Qin; Nan Hu; Elizabeth Taylor; Oliver Dibben; Andrea Stacey; Jacques Fellay; Kevin V Shianna; Frederick Siegal; Michael Shodell; Kokila Shah; Marie Larsson; Jeffrey Lifson; Arthur Nadas; Michael Marmor; Richard Hutt; David Margolis; Donald Garmon; Martin Markowitz; Fred Valentine; Persephone Borrow; Nina Bhardwaj
Evidence of dysregulation of dendritic cells in primary HIV infection.
Blood 2010;116(19):3839-52.
2010: Anne Gallois; Nina Bhardwaj
A needle in the 'cancer vaccine' haystack.
Nature medicine 2010;16(8):854-6.
2010: Alice W Yewdall; Scott B Drutman; Felecia Jinwala; Keith S Bahjat; Nina Bhardwaj
CD8+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells.
PloS one 2010;5(6):e11144.
2010: Rachel Lubong Sabado; Nina Bhardwaj
Directing dendritic cell immunotherapy towards successful cancer treatment.
Immunotherapy 2010;2(1):37-56.
2010: Nikoletta Lendvai; Sacha Gnjatic; Erika Ritter; Michael Mangone; Wayne Austin; Karina Reyner; David Jayabalan; Ruben Niesvizky; Sundar Jagannath; Nina Bhardwaj; Selina Chen-Kiang; Lloyd J Old; Hearn Jay Cho
Cellular immune responses against CT7 (MAGE-C1) and humoral responses against other cancer-testis antigens in multiple myeloma patients.
Cancer immunity 2010;10():4.
2009: Olivier Manches; Nina Bhardwaj
Resolution of immune activation defines nonpathogenic SIV infection.
The Journal of clinical investigation 2009;119(12):3512-5.
2009: Dusan Bogunovic; David W O'Neill; Ilana Belitskaya-Levy; Vladimir Vacic; Yi-Lo Yu; Sylvia Adams; Farbod Darvishian; Russell Berman; Richard Shapiro; Anna C Pavlick; Stefano Lonardi; Jiri Zavadil; Iman Osman; Nina Bhardwaj
Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(48):20429-34.
2009: Shaukat Khan; Jeffrey D Greenberg; Nina Bhardwaj
Dendritic cells as targets for therapy in rheumatoid arthritis.
Nature reviews. Rheumatology 2009;5(10):566-71.
2009: Saba Alzabin; Nina Bhardwaj; Friedemann Kiefer; Sansana Sawasdikosol; Steven Burakoff
Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6187-94.
2009: Kathryn E O'Reilly; Melanie Warycha; Michael A Davies; Vanessa Rodrik-Outmezguine; Xi Kathy Zhou; Herman Yee; David Polsky; Anna Pavlick; Neal Rosen; Nina Bhardwaj; Gordon Mills; Iman Osman
Phosphorylated 4E-BP1 is associated with poor survival in melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(8):2872-8.
2009: Lindsay G Wich; Heather K Hamilton; Richard L Shapiro; Anna Pavlick; Russell S Berman; David Polsky; Judith D Goldberg; Eva Hernando; Prashiela Manga; Michelle Krogsgaard; Hideko Kamino; Farbod Darvishian; Peng Lee; Seth J Orlow; Harry Ostrer; Nina Bhardwaj; Iman Osman
Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research.
American journal of translational research 2009;1(1):35-43.
2009: Rachel Lubong Sabado; Daniel G Kavanagh; Daniel E Kaufmann; Karlhans Fru; Ethan Babcock; Eric Rosenberg; Bruce Walker; Jeffrey D Lifson; Nina Bhardwaj; Marie Larsson
In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.
PloS one 2009;4(1):e4256.
2008: mojca skoberne; Alice Yewdall; Keith S Bahjat; Emmanuelle Godefroy; Peter Lauer; Edward Lemmens; Weiqun Liu; Will Luckett; Meredith Leong; Thomas W Dubensky; Dirk G Brockstedt; Nina Bhardwaj
KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity.
The Journal of clinical investigation 2008;118(12):3990-4001.
2008: Kira Minkis; Daniel G Kavanagh; Galit Alter; Dusan Bogunovic; David O'Neill; Sylvia Adams; Anna Pavlick; Bruce D Walker; Mark Alan Brockman; Rajesh T Gandhi; Nina Bhardwaj
Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells.
Cancer research 2008;68(22):9441-50.
2008: Olivier Manches; David H Munn; Anahita Fallahi; Jeffrey D Lifson; Laurence Chaperot; Joel Plumas; Nina Bhardwaj
HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism.
The Journal of clinical investigation 2008;118(10):3431-9.
2008: Sylvia Adams; Michelle A Lowes; David W O'Neill; Stephen Schachterle; Pedro Romero; Nina Bhardwaj
Lack of functionally active Melan-A(26-35)-specific T cells in the blood of HLA-A2+ vitiligo patients.
The Journal of investigative dermatology 2008;128(8):1977-80.
2008: Sylvia Adams; David W O'Neill; Daisuke Nonaka; Elizabeth Hardin; Luis Chiriboga; Kimberly Siu; Crystal M Cruz; Angelica Angiulli; Francesca Angiulli; Erika Ritter; Rose Marie Holman; Richard L Shapiro; Russell S Berman; Natalie Berner; Yongzhao Shao; Olivier Manches; Linda Pan; Ralph R Venhaus; Eric W Hoffman; Achim Jungbluth; Sacha Gnjatic; Lloyd J Old; Anna C Pavlick; Nina Bhardwaj
Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):776-84.
2008: Sneha Mathew; Kristy L Bauer; Arne Fischoeder; Nina Bhardwaj; Stephen J Oliver
The anergic state in sarcoidosis is associated with diminished dendritic cell function.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):746-55.
2008: Persephone Borrow; Nina Bhardwaj
Innate immune responses in primary HIV-1 infection.
Current opinion in HIV and AIDS 2008;3(1):36-44.
2007: Rachel L Sabado; Ethan Babcock; Daniel G Kavanagh; Veronica Tjomsland; Bruce D Walker; Jeffrey D Lifson; Nina Bhardwaj; Marie Larsson
Pathways utilized by dendritic cells for binding, uptake, processing and presentation of antigens derived from HIV-1.
European journal of immunology 2007;37(7):1752-63.
2007: David W O'Neill; Nina Bhardwaj
Exploiting dendritic cells for active immunotherapy of cancer and chronic infections.
Molecular biotechnology 2007;36(2):131-41.
2007: Danila Valmori; Naira E Souleimanian; Valeria Tosello; Nina Bhardwaj; Sylvia Adams; David O'Neill; Anna Pavlick; Juliet B Escalon; Crystal M Cruz; Angelica Angiulli; Francesca Angiulli; Gregory Mears; Susan M Vogel; Linda Pan; Achim A Jungbluth; Eric W Hoffmann; Ralph Venhaus; Gerd Ritter; Lloyd J Old; Maha Ayyoub
Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8947-52.
2007: Nina Bhardwaj
Harnessing the immune system to treat cancer.
The Journal of clinical investigation 2007;117(5):1130-6.
2007: Elsa F Velazquez; Achim A Jungbluth; Molly Yancovitz; Sacha Gnjatic; Sylvia Adams; David O'Neill; Kira Zavilevich; Tatyana Albukh; Paul J Christos; Madhu Mazumdar; Anna Pavlick; David Polsky; Richard Shapiro; Russell Berman; Joanna Spira; Klaus J Busam; Iman Osman; Nina Bhardwaj
Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)--correlation with prognostic factors.
Cancer immunity 2007;7():11.
2007: Elsa F Velazquez; Molly Yancovitz; Anna Pavlick; Russell Berman; Richard Shapiro; Dusan Bogunovic; David O'Neill; Yi-Lo Yu; Joanna Spira; Paul J Christos; Xi Kathy Zhou; Madhu Mazumdar; David M Nanus; Leonard Liebes; Nina Bhardwaj; David Polsky; Iman Osman
Clinical relevance of neutral endopeptidase (NEP/CD10) in melanoma.
Journal of translational medicine 2007;5():2.
2006: mojca skoberne; Selin Somersan; Wanda Almodovar; Tuan Truong; Kseniya Petrova; Peter M Henson; Nina Bhardwaj
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
Blood 2006;108(3):947-55.
2005: Anne-Sophie Beignon; Kelli McKenna; mojca skoberne; Olivier Manches; Ida Dasilva; Daniel G Kavanagh; Marie Larsson; Robert J Gorelick; Jeffrey D Lifson; Nina Bhardwaj
Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions.
The Journal of clinical investigation 2005;115(11):3265-75.
2005: Sandra Demaria; Nina Bhardwaj; william mcbride; Silvia C Formenti
Combining radiotherapy and immunotherapy: a revived partnership.
International journal of radiation oncology, biology, physics 2005;63(3):655-66.
2005: David W O'Neill; Nina Bhardwaj
Differentiation of peripheral blood monocytes into dendritic cells.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2005;Chapter 22():Unit 22F.4.
2005: Sylvia Adams; David W O'Neill; Nina Bhardwaj
Recent advances in dendritic cell biology.
Journal of clinical immunology 2005;25(3):177-88.
2005: Sylvia Adams; David W O'Neill; Nina Bhardwaj
Recent advances in dendritic cell biology.
Journal of clinical immunology 2005;25(2):87-98.
2005: mojca skoberne; Anne-Sophie Beignon; Marie Larsson; Nina Bhardwaj
Apoptotic cells at the crossroads of tolerance and immunity.
Current topics in microbiology and immunology 2005;289():259-92.
2005: Kelli McKenna; Anne-Sophie Beignon; Nina Bhardwaj
Plasmacytoid dendritic cells: linking innate and adaptive immunity.
Journal of virology 2005;79(1):17-27.
2005: David O'Neill; Nina Bhardwaj
Generation of autologous peptide- and protein-pulsed dendritic cells for patient-specific immunotherapy.
Methods in molecular medicine 2005;109():97-112.
2005: David O'Neill; Nina Bhardwaj
Exploiting dendritic cells for active immunotherapy of cancer and chronic infection.
Methods in molecular medicine 2005;109():1-18.
2004: David W O'Neill; Sylvia Adams; Nina Bhardwaj
Manipulating dendritic cell biology for the active immunotherapy of cancer.
Blood 2004;104(8):2235-46.
2004: mojca skoberne; Anne-Sophie Beignon; Nina Bhardwaj
Danger signals: a time and space continuum.
Trends in molecular medicine 2004;10(6):251-7.
2004: Marie Larsson; Ethan Babcock; Arash Grakoui; Naglaa H Shoukry; Georg Lauer; Charles Rice; Christopher Walker; Nina Bhardwaj
Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.
Journal of virology 2004;78(12):6151-61.
2004: Marie Larsson; Anne-Sophie Beignon; Nina Bhardwaj
DC-virus interplay: a double edged sword.
Seminars in immunology 2004;16(3):147-61.
2004: Jean-François Fonteneau; Marie Larsson; Anne-Sophie Beignon; Kelli McKenna; Ida Dasilva; Ali Amara; Yong-Jun Liu; Jeffrey D Lifson; Dan R Littman; Nina Bhardwaj
Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells.
Journal of virology 2004;78(10):5223-32.
2003: Jean-François Fonteneau; Daniel G Kavanagh; Margareta Lirvall; Catherine Sanders; Timothy L Cover; Nina Bhardwaj; Marie Larsson
Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells.
Blood 2003;102(13):4448-55.
2003: Anne-Sophie Beignon; mojca skoberne; Nina Bhardwaj
Type I interferons promote cross-priming: more functions for old cytokines.
Nature immunology 2003;4(10):939-41.
2003: Jean-François Fonteneau; Michel Gilliet; Marie Larsson; Ida Dasilva; Christian Münz; Yong-Jun Liu; Nina Bhardwaj
Activation of influenza virus-specific CD4+ and CD8+ T cells: a new role for plasmacytoid dendritic cells in adaptive immunity.
Blood 2003;101(9):3520-6.
2003: Johan K Sandberg; Nina Bhardwaj; Douglas F Nixon
Dominant effector memory characteristics, capacity for dynamic adaptive expansion, and sex bias in the innate Valpha24 NKT cell compartment.
European journal of immunology 2003;33(3):588-96.
2003: Marie Larsson; Jean-François Fonteneau; Nina Bhardwaj
Cross-presentation of cell-associated antigens by dendritic cells.
Current topics in microbiology and immunology 2003;276():261-75.
2002: Andrew W Lee; Tuan Truong; Kara Bickham; Jean-François Fonteneau; Marie Larsson; Ida Da Silva; Selin Somersan; Elaine K Thomas; Nina Bhardwaj
A clinical grade cocktail of cytokines and PGE2 results in uniform maturation of human monocyte-derived dendritic cells: implications for immunotherapy.
Vaccine 2002;20 Suppl 4():A8-A22.
2002: Johan K Sandberg; Noam M Fast; Emil H Palacios; Glenn Fennelly; Joanna Dobroszycki; Paul Palumbo; Andrew Wiznia; Robert M Grant; Nina Bhardwaj; Michael G Rosenberg; Douglas F Nixon
Selective loss of innate CD4(+) V alpha 24 natural killer T cells in human immunodeficiency virus infection.
Journal of virology 2002;76(15):7528-34.
2002: Jean-François Fonteneau; Marie Larsson; Nina Bhardwaj
Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses.
Current opinion in immunology 2002;14(4):471-7.
2002: Barbara L Shacklett; Robert E Means; Marie Larsson; David T Wilkens; Thomas J Beadle; Melissa J Merritt; Nina Bhardwaj; Paul E Palumbo; Joan Skurnick; Donald B Louria; Douglas F Nixon
Dendritic cell amplification of HIV type 1-specific CD8+ T cell responses in exposed, seronegative heterosexual women.
AIDS research and human retroviruses 2002;18(11):805-15.
2002: Marie Larsson; Jean-François Fonteneau; Margareta Lirvall; Patrick A J Haslett; Jeffrey D Lifson; Nina Bhardwaj
Activation of HIV-1 specific CD4 and CD8 T cells by human dendritic cells: roles for cross-presentation and non-infectious HIV-1 virus.
AIDS (London, England) 2002;16(10):1319-29.
2002: Marie Larsson; David T Wilkens; Jean-François Fonteneau; Thomas J Beadle; Melissa J Merritt; Rhonda Kost; Patrick A J Haslett; Susan Cu-Uvin; Nina Bhardwaj; Douglas F Nixon; Barbara L Shacklett
Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells.
AIDS (London, England) 2002;16(2):171-80.
2002: Gabriel M Ortiz; Jennifer Hu; Joshua A Goldwitz; Rohit Chandwani; Marie Larsson; Nina Bhardwaj; Sebastian Bonhoeffer; Bharat Ramratnam; Linqi Zhang; Martin Markowitz; Douglas F Nixon
Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection.
Journal of virology 2002;76(1):411-5.
2001: Marie Larsson; Jean-François Fonteneau; Selin Somersan; Catherine Sanders; Kara Bickham; Elaine K Thomas; Karsten Mahnke; Nina Bhardwaj
Efficiency of cross presentation of vaccinia virus-derived antigens by human dendritic cells.
European journal of immunology 2001;31(12):3432-42.
2001: Jean-François Fonteneau; Marie Larsson; Selin Somersan; Catherine Sanders; Christian Münz; W W Kwok; Nina Bhardwaj; Francine Jotereau
Generation of high quantities of viral and tumor-specific human CD4+ and CD8+ T-cell clones using peptide pulsed mature dendritic cells.
Journal of immunological methods 2001;258(1-2):111-26.
2001: Selin Somersan; Nina Bhardwaj
Tethering and tickling: a new role for the phosphatidylserine receptor.
The Journal of cell biology 2001;155(4):501-4.
2001: Selin Somersan; Marie Larsson; Jean-François Fonteneau; S Basu; P Srivastava; Nina Bhardwaj
Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):4844-52.
2001: Nina Bhardwaj
Processing and presentation of antigens by dendritic cells: implications for vaccines.
Trends in molecular medicine 2001;7(9):388-94.
2001: Marie Larsson; Jean-François Fonteneau; Nina Bhardwaj
Dendritic cells resurrect antigens from dead cells.
Trends in immunology 2001;22(3):141-8.
2001: J Engelmayer; Marie Larsson; A Lee; M Lee; WI Cox; Ralph M Steinman; Nina Bhardwaj
Mature dendritic cells infected with canarypox virus elicit strong anti-human immunodeficiency virus CD8+ and CD4+ T-cell responses from chronically infected individuals.
Journal of virology 2001;75(5):2142-53.
2001: Madhav V Dhodapkar; Ralph M Steinman; Joseph Krasovsky; C Munz; Nina Bhardwaj
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells.
The Journal of experimental medicine 2001;193(2):233-8.
2001: Kara Bickham; Christian Münz; Ming L Tsang; Marie Larsson; Jean-François Fonteneau; Nina Bhardwaj; R Steinman
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function.
The Journal of clinical investigation 2001;107(1):121-30.
2000: Madhav V Dhodapkar; James W Young; Paul B Chapman; W I Cox; Jean-François Fonteneau; S Amigorena; Alan N Houghton; Ralph M Steinman; Nina Bhardwaj
Paucity of functional T-cell memory to melanoma antigens in healthy donors and melanoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4831-8.
2000: Marie Larsson; Davorka Messmer; Selin Somersan; Jean-François Fonteneau; Sean M Donahoe; M Lee; P R Dunbar; V Cerundolo; I Julkunen; Douglas F Nixon; Nina Bhardwaj
Requirement of mature dendritic cells for efficient activation of influenza A-specific memory CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1182-90.
2000: Madhav V Dhodapkar; Nina Bhardwaj
Active immunization of humans with dendritic cells.
Journal of clinical immunology 2000;20(3):167-74.
2000: Madhav V Dhodapkar; Joseph Krasovsky; Ralph M Steinman; Nina Bhardwaj
Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes.
The Journal of clinical investigation 2000;105(6):R9-R14.
2000: B Sauter; Matthew L Albert; LM Francisco; Marie Larsson; Selin Somersan; Nina Bhardwaj
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells.
The Journal of experimental medicine 2000;191(3):423-34.
2000: Xia Jin; C G Roberts; Douglas F Nixon; Jeffrey T Safrit; L Q Zhang; Y X Huang; Nina Bhardwaj; B Jesdale; A S DeGroot; RA Koup
Identification of subdominant cytotoxic T lymphocyte epitopes encoded by autologous HIV type 1 sequences, using dendritic cell stimulation and computer-driven algorithm.
AIDS research and human retroviruses 2000;16(1):67-76.
1999: J Engelmayer; Marie Larsson; Marion Subklewe; A Chahroudi; WI Cox; Ralph M Steinman; Nina Bhardwaj
Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6762-8.
1999: Marion Subklewe; A Chahroudi; Kara Bickham; Marie Larsson; Michael Kurilla; Nina Bhardwaj; Ralph M Steinman
Presentation of epstein-barr virus latency antigens to CD8(+), interferon-gamma-secreting, T lymphocytes.
European journal of immunology 1999;29(12):3995-4001.
1999: Marion Subklewe; A Chahroudi; Alan L Schmaljohn; Michael Kurilla; Nina Bhardwaj; Ralph M Steinman
Induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses using dendritic cells pulsed with EBNA-3A peptides or UV-inactivated, recombinant EBNA-3A vaccinia virus.
Blood 1999;94(4):1372-81.
1999: Hans M L Spiegel; E DeFalcon; Graham S Ogg; Marie Larsson; Thomas J Beadle; P Tao; Andrew J McMichael; Nina Bhardwaj; C O'Callaghan; W I Cox; Keith Krasinski; Henry Pollack; William Borkowsky; Douglas F Nixon
Changes in frequency of HIV-1-specific cytotoxic T cell precursors and circulating effectors after combination antiretroviral therapy in children.
The Journal of infectious diseases 1999;180(2):359-68.
1999: Madhav V Dhodapkar; Ralph M Steinman; M Sapp; H Desai; C Fossella; Joseph Krasovsky; Sean M Donahoe; P R Dunbar; V Cerundolo; Douglas F Nixon; Nina Bhardwaj
Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells.
The Journal of clinical investigation 1999;104(2):173-80.
1999: Marie Larsson; Xia Jin; Bharat Ramratnam; Graham S Ogg; J Engelmayer; MA Demoitie; Andrew J McMichael; WI Cox; Ralph M Steinman; D Nixon; Nina Bhardwaj
A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals.
AIDS (London, England) 1999;13(7):767-77.
1999: M Sapp; J Engelmayer; Marie Larsson; Angela Granelli-Piperno; R Steinman; Nina Bhardwaj
Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses.
Immunology letters 1999;66(1-3):121-8.
1998: Kayo Inaba; Shannon Turley; F Yamaide; Tomonori Iyoda; Karsten Mahnke; M Inaba; Maggi Pack; Marion Subklewe; B Sauter; David Sheff; M Albert; Nina Bhardwaj; Ira Mellman; Ralph M Steinman
Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells.
The Journal of experimental medicine 1998;188(11):2163-73.
1998: Matthew L Albert; Jennifer C Darnell; A Bender; LM Francisco; Nina Bhardwaj; Robert B Darnell
Tumor-specific killer cells in paraneoplastic cerebellar degeneration.
Nature medicine 1998;4(11):1321-4.
1998: Matthew L Albert; SF Pearce; LM Francisco; B Sauter; P Roy; Roy L Silverstein; Nina Bhardwaj
Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes.
The Journal of experimental medicine 1998;188(7):1359-68.
1998: Matthew L Albert; B Sauter; Nina Bhardwaj
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs.
Nature 1998;392(6671):86-9.
1998: LM Austin; TR Coven; Nina Bhardwaj; R Steinman; James G Krueger
Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17(TIA-1)+CD8+CD3+ CTLs as determined by phenotypic analysis.
Journal of cutaneous pathology 1998;25(2):79-88.
1997: A Reddy; M Sapp; M Feldman; Marion Subklewe; Nina Bhardwaj
A monocyte conditioned medium is more effective than defined cytokines in mediating the terminal maturation of human dendritic cells.
Blood 1997;90(9):3640-6.
1997: Nina Bhardwaj
Interactions of viruses with dendritic cells: a double-edged sword.
The Journal of experimental medicine 1997;186(6):795-9.
1996: Angela Granelli-Piperno; B Moser; Melissa Pope; D Chen; Y Wei; F Isdell; Una O'Doherty; William A Paxton; R Koup; S Mojsov; Nina Bhardwaj; I Clark-Lewis; M Baggiolini; Ralph M Steinman
Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors.
The Journal of experimental medicine 1996;184(6):2433-8.
1996: A Bender; M Sapp; Gerold Schuler; Ralph M Steinman; Nina Bhardwaj
Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood.
Journal of immunological methods 1996;196(2):121-35.
1996: Nina Bhardwaj; R A Seder; A Reddy; M V Feldman
IL-12 in conjunction with dendritic cells enhances antiviral CD8+ CTL responses in vitro.
The Journal of clinical investigation 1996;98(3):715-22.
1995: A Bender; L K Bui; M A Feldman; M Larsson; Nina Bhardwaj
Inactivated influenza virus, when presented on dendritic cells, elicits human CD8+ cytolytic T cell responses.
The Journal of experimental medicine 1995;182(6):1663-71.
1995: Nina Bhardwaj; A Bender; N Gonzalez; L K Bui; M C Garrett; Ralph M Steinman
Stimulation of human anti-viral CD8+ cytolytic T lymphocytes by dendritic cells.
Advances in experimental medicine and biology 1995;378():375-9.
1994: Nina Bhardwaj; A Bender; N Gonzalez; L K Bui; M C Garrett; Ralph M Steinman
Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.
The Journal of clinical investigation 1994;94(2):797-807.
1994: Una O'Doherty; M Peng; S Gezelter; W J Swiggard; M Betjes; Nina Bhardwaj; Ralph M Steinman
Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature.
Immunology 1994;82(3):487-93.
1994: Nina Bhardwaj; A S Hodtsev; A Nisanian; S Kabak; S M Friedman; B C Cole; David N Posnett
Human T-cell responses to Mycoplasma arthritidis-derived superantigen.
Infection and immunity 1994;62(1):135-44.
1993: P Pancholi; A Mirza; V Schauf; Ralph M Steinman; Nina Bhardwaj
Presentation of mycobacterial antigens by human dendritic cells: lack of transfer from infected macrophages.
Infection and immunity 1993;61(12):5326-32.
1993: Una O'Doherty; Ralph M Steinman; M Peng; paul cameron; S Gezelter; I Kopeloff; W J Swiggard; Melissa Pope; Nina Bhardwaj
Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.
The Journal of experimental medicine 1993;178(3):1067-76.
1993: David N Posnett; A S Hodtsev; S Kabak; S M Friedman; B C Cole; Nina Bhardwaj
Interaction of Mycoplasma arthritidis superantigen with human T cells.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1993;17 Suppl 1():S170-5.
1993: Nina Bhardwaj; James W Young; A J Nisanian; J Baggers; Ralph M Steinman
Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses.
The Journal of experimental medicine 1993;178(2):633-42.
1993: P Pancholi; A Mirza; Nina Bhardwaj; Ralph M Steinman
Sequestration from immune CD4+ T cells of mycobacteria growing in human macrophages.
Science (New York, N.Y.) 1993;260(5110):984-6.
1993: Una O'Doherty; W J Swiggard; Kayo Inaba; Y Yamaguchi; I Kopeloff; Nina Bhardwaj; Ralph M Steinman
Tolerizing mice to human leukocytes: a step toward the production of monoclonal antibodies specific for human dendritic cells.
Advances in experimental medicine and biology 1993;329():165-72.
1992: P Pancholi; Ralph M Steinman; Nina Bhardwaj
Dendritic cells efficiently immunoselect mycobacterial-reactive T cells in human blood, including clonable antigen-reactive precursors.
Immunology 1992;76(2):217-24.
1992: Nina Bhardwaj; S M Friedman; B C Cole; A J Nisanian
Dendritic cells are potent antigen-presenting cells for microbial superantigens.
The Journal of experimental medicine 1992;175(1):267-73.
1991: P Pancholi; Ralph M Steinman; Nina Bhardwaj
An approach to isolating T cell lines that react to antigens presented on the surface of dendritic cells.
Clinical and experimental immunology 1991;85(2):349-56.
1990: P S Freudenthal; Nina Bhardwaj
Dendritic cells in human blood and synovial exudates.
International reviews of immunology 1990;6(2-3):103-16.
1989: Nina Bhardwaj; U Santhanam; L L Lau; S B Tatter; J Ghrayeb; M Rivelis; Ralph M Steinman; Pravin B Sehgal; L T May
IL-6/IFN-beta 2 in synovial effusions of patients with rheumatoid arthritis and other arthritides. Identification of several isoforms and studies of cellular sources.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(7):2153-9.
1989: Nina Bhardwaj; L L Lau; S M Friedman; Mary Crow; Ralph M Steinman
Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes.
The Journal of experimental medicine 1989;169(3):1121-36.
1989: D C Helfgott; S B Tatter; U Santhanam; R H Clarick; Nina Bhardwaj; L T May; Pravin B Sehgal
Multiple forms of IFN-beta 2/IL-6 in serum and body fluids during acute bacterial infection.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(3):948-53.
1988: Nina Bhardwaj; L L Lau; M Rivelis; Ralph M Steinman
Interleukin-1 production by mononuclear cells from rheumatoid synovial effusions.
Cellular immunology 1988;114(2):405-23.
1988: L T May; U Santhanam; S B Tatter; Nina Bhardwaj; J Ghrayeb; Pravin B Sehgal
Phosphorylation of secreted forms of human beta 2-interferon/hepatocyte stimulating factor/interleukin-6.
Biochemical and biophysical research communications 1988;152(3):1144-50.