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Jason Rausch

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TOP 3
Joanna Sztuba-Solinska; Tadahisa Teramoto; Radhakrishnan Padmanabhan; Jason W Rausch; Bruce A Shapiro; Stuart F J Le Grice
Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome.
Elzbieta Nowak; Wojciech Potrzebowski; Jason W Rausch; Dmitri I Svergun; Marion K Bona; Janusz M Bujnicki; Petr V Konarev; Stuart F J Le Grice; Marcin Nowotny
Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid.
Suhman Chung; Daniel M Himmel; Jian-Kang Jiang; Jason W Rausch; Craig J Thomas; Jennifer A Wilson; Krzysztof Wojtak; Eddy Arnold; Joseph D Bauman; John A Beutler; Stuart F J Le Grice
Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.

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All Publications

2013: Joanna Sztuba-Solinska; Tadahisa Teramoto; Radhakrishnan Padmanabhan; Jason W Rausch; Bruce A Shapiro; Stuart F J Le Grice
Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome.
Nucleic acids research 2013;41(9):5075-89.
2013: Elzbieta Nowak; Wojciech Potrzebowski; Jason W Rausch; Dmitri I Svergun; Marion K Bona; Janusz M Bujnicki; Petr V Konarev; Stuart F J Le Grice; Marcin Nowotny
Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid.
Nucleic acids research 2013;41(6):3874-87.
2011: Suhman Chung; Daniel M Himmel; Jian-Kang Jiang; Jason W Rausch; Craig J Thomas; Jennifer A Wilson; Krzysztof Wojtak; Eddy Arnold; Joseph D Bauman; John A Beutler; Stuart F J Le Grice
Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.
Journal of medicinal chemistry 2011;54(13):4462-73.
2010: Suhman Chung; Michaela Wendeler; Jason W Rausch; Greg Beilhartz; Matthias Gotte; Barry R O'Keefe; Alun Bermingham; John A Beutler; Shixin Liu; Xiaowei Zhuang; Stuart F J Le Grice
Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H.
Antimicrobial agents and chemotherapy 2010;54(9):3913-21.
2010: Nancy P-Y Chung; Sabine K J Breun; Arman Bashirova; Joerg G Baumann; Thomas D Martin; Jaideep M Karamchandani; Jason W Rausch; Stuart F J Le Grice; Li Wu; Mary Carrington; Vineet N KewalRamani
HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN).
The Journal of biological chemistry 2010;285(3):2100-12.
2009: Jason W Rausch; Linda Chelico; Myron F Goodman; Stuart F J Le Grice
Dissecting APOBEC3G substrate specificity by nucleoside analog interference.
The Journal of biological chemistry 2009;284(11):7047-58.
2008: Kevin B Turner; Robert G Brinson; Hye Young Yi-Brunozzi; Jason W Rausch; Jennifer T Miller; Stuart F J Le Grice; John P Marino; Daniele Fabris
Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands.
Nucleic acids research 2008;36(8):2799-810.
2007: Jason W Rausch; Stuart F J Le Grice
Exploiting structurally diverse nucleoside analogs as probes of reverse transcription complexes.
Current HIV research 2007;5(1):11-22.
2007: Jason W Rausch; Stuart F J Le Grice
Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis.
Nucleic acids research 2007;35(1):256-68.
2004: Jason W Rausch; Stuart F J Le Grice
'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virus.
The international journal of biochemistry & cell biology 2004;36(9):1752-66.
2004: Chandravanu Dash; Jason W Rausch; Stuart F J Le Grice
Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract.
Nucleic acids research 2004;32(4):1539-47.
2003: Jason W Rausch; Jin Qu; Hye Young Yi-Brunozzi; Eric T Kool; Stuart F J Le Grice
Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11279-84.
2002: Jason V Cristofaro; Jason W Rausch; Stuart F J Le Grice; Jeffrey J. DeStefano
Mutations in the ribonuclease H active site of HIV-RT reveal a role for this site in stabilizing enzyme-primer-template binding.
Biochemistry 2002;41(36):10968-75.
2002: Jason W Rausch; Daniela Lener; Jennifer T Miller; John G Julias; Stephen H Hughes; Stuart F J Le Grice
Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity.
Biochemistry 2002;41(15):4856-65.
2001: Inna I Gorshkova; Jason W Rausch; Stuart F J Le Grice; Robert J Crouch
HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes.
Analytical biochemistry 2001;291(2):198-206.
2001: Jennifer T Miller; Jason W Rausch; Stuart F J Le Grice
Evaluation of retroviral ribonuclease H activity.
Methods in molecular biology (Clifton, N.J.) 2001;160():335-54.
2000: Jason W Rausch; Bangalore Sathyanarayana; Marion K Bona; Stuart F J Le Grice
Probing contacts between the ribonuclease H domain of HIV-1 reverse transcriptase and nucleic acid by site-specific photocross-linking.
The Journal of biological chemistry 2000;275(21):16015-22.
2000: Jason W Rausch; M K Grice; M Henrietta; Jennifer T Miller; Stuart F J Le Grice
Interaction of p55 reverse transcriptase from the Saccharomyces cerevisiae retrotransposon Ty3 with conformationally distinct nucleic acid duplexes.
The Journal of biological chemistry 2000;275(18):13879-87.
2000: James A Cowan; T Ohyama; K Howard; Jason W Rausch; S M Cowan; Stuart F J Le Grice
Metal-ion stoichiometry of the HIV-1 RT ribonuclease H domain: evidence for two mutually exclusive sites leads to new mechanistic insights on metal-mediated hydrolysis in nucleic acid biochemistry.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2000;5(1):67-74.
1999: S R Stetor; Jason W Rausch; M J Guo; J P Burnham; L R Boone; M J Waring; Stuart F J Le Grice
Characterization of (+) strand initiation and termination sequences located at the center of the equine infectious anemia virus genome.
Biochemistry 1999;38(12):3656-67.
1997: Jason W Rausch; Stuart F J Le Grice
Substituting a conserved residue of the ribonuclease H domain alters substrate hydrolysis by retroviral reverse transcriptase.
The Journal of biological chemistry 1997;272(13):8602-10.
1996: Eric J Arts; S R Stetor; X Li; Jason W Rausch; Kathryn Howard; B Ehresmann; T W North; Birgitta M Wöhrl; Roger S Goody; Mark A Wainberg; S F Grice
Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10063-8.
1996: Jason W Rausch; Eric J Arts; Birgitta M Wöhrl; Stuart F J Le Grice
Involvement of C-terminal structural elements of equine infectious anemia virus reverse transcriptase in DNA polymerase and ribonuclease H activities.
Journal of molecular biology 1996;257(3):500-11.
1995: N M Cirino; Craig E Cameron; J S Smith; Jason W Rausch; M J Roth; S J Benkovic; Stuart F J Le Grice
Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase.
Biochemistry 1995;34(31):9936-43.
1994: Susan L Payne; Jason W Rausch; K Rushlow; Ronald Montelaro; Charles J Issel; M Flaherty; S Perry; D Sellon; Frederick J Fuller
Characterization of infectious molecular clones of equine infectious anaemia virus.
The Journal of general virology 1994;75 ( Pt 2)():425-9.