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Ehud Razin

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Yifat Ofir-Birin; Jorge Pozo; Inbal Rachmin; Ehud Razin; Paul Schimmel; Ryan Shapiro; Jing Song; Jing Wang; Xiang-Lei Yang; Hui-Min Zhang; Steven P Bennett; Arie Dagan; Pengfei Fang; Sunghoon Kim; Alan G Marshall; hovav nechushtan; Min Guo
Structural switch of lysyl-tRNA synthetase between translation and transcription.
Zohar Yagil; Zanna Yekhtin; Chang Cheng; David E Fisher; Tal Hadad Erlich; Karin Hartmann; Gillian Kay; Yifat Ofir-Birin; Ehud Razin; Sagi Tshori; W S Fred Wong; hovav nechushtan
Transcription factor E3, a major regulator of mast cell-mediated allergic response.
Irit Carmi-Levy; Alex Motzik; Yifat Ofir-Birin; Zohar Yagil; Christopher Maolin Yang; David Michael Kemeny; Jung Min Han; Sunghoon Kim; Gillian Kay; hovav nechushtan; Ryo Suzuki; Juan Rivera; Ehud Razin
Importin beta plays an essential role in the regulation of the LysRS-Ap(4)A pathway in immunologically activated mast cells.

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All Publications

2013: Yifat Ofir-Birin; Jorge Pozo; Inbal Rachmin; Ehud Razin; Paul Schimmel; Ryan Shapiro; Jing Song; Jing Wang; Xiang-Lei Yang; Hui-Min Zhang; Steven P Bennett; Arie Dagan; Pengfei Fang; Sunghoon Kim; Alan G Marshall; hovav nechushtan; Min Guo
Structural switch of lysyl-tRNA synthetase between translation and transcription.
Molecular cell 2013;49(1):30-42.
2012: Zohar Yagil; Zanna Yekhtin; Chang Cheng; David E Fisher; Tal Hadad Erlich; Karin Hartmann; Gillian Kay; Yifat Ofir-Birin; Ehud Razin; Sagi Tshori; W S Fred Wong; hovav nechushtan
Transcription factor E3, a major regulator of mast cell-mediated allergic response.
The Journal of allergy and clinical immunology 2012;129(5):1357-1366.e5.
2011: Irit Carmi-Levy; Alex Motzik; Yifat Ofir-Birin; Zohar Yagil; Christopher Maolin Yang; David Michael Kemeny; Jung Min Han; Sunghoon Kim; Gillian Kay; hovav nechushtan; Ryo Suzuki; Juan Rivera; Ehud Razin
Importin beta plays an essential role in the regulation of the LysRS-Ap(4)A pathway in immunologically activated mast cells.
Molecular and cellular biology 2011;31(10):2111-21.
2010: Sagi Tshori; Ehud Razin
Editorial: Mast cell degranulation and calcium entry--the Fyn-calcium store connection.
Journal of leukocyte biology 2010;88(5):837-8.
2010: Zohar Yagil; hovav nechushtan; Gillian Kay; Christopher M Yang; David M Kemeny; Ehud Razin
The enigma of the role of protein inhibitor of activated STAT3 (PIAS3) in the immune response.
Trends in immunology 2010;31(5):199-204.
2009: Nurit Yannay-Cohen; Irit Carmi-Levy; Gillian Kay; Christopher Maolin Yang; Jung Min Han; D Michael Kemeny; Sunghoon Kim; hovav nechushtan; Ehud Razin
LysRS serves as a key signaling molecule in the immune response by regulating gene expression.
Molecular cell 2009;34(5):603-11.
2009: Zohar Yagil; Gillian Kay; hovav nechushtan; Ehud Razin
A specific epitope of protein inhibitor of activated STAT3 is responsible for the induction of apoptosis in rat transformed mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2168-75.
2009: hovav nechushtan; Sunghoon Kim; Gillian Kay; Ehud Razin
Chapter 1: The physiological role of lysyl tRNA synthetase in the immune system.
Advances in immunology 2009;103():1-27.
2008: Irit Carmi-Levy; Nurit Yannay-Cohen; Gillian Kay; Ehud Razin; hovav nechushtan
Diadenosine tetraphosphate hydrolase is part of the transcriptional regulation network in immunologically activated mast cells.
Molecular and cellular biology 2008;28(18):5777-84.
2007: Björn Textor; Alexander H Licht; Jan P Tuckermann; Rolf Jessberger; Ehud Razin; Peter Angel; Marina Schorpp-Kistner; Bettina Hartenstein
JunB is required for IgE-mediated degranulation and cytokine release of mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6873-80.
2007: Irit Carmi; Ehud Razin
The role played by key transcription factors in activated mast cells.
Immunological reviews 2007;217():280-91.
2007: Sagi Tshori; Amir Sonnenblick; Nurit Yannay-Cohen; Gillian Kay; hovav nechushtan; Ehud Razin
Microphthalmia transcription factor isoforms in mast cells and the heart.
Molecular and cellular biology 2007;27(11):3911-9.
2006: Nurit Yannay-Cohen; Ehud Razin
Translation and transcription: the dual functionality of LysRS in mast cells.
Molecules and cells 2006;22(2):127-32.
2006: Sagi Tshori; Dan GILON; Ronen Beeri; hovav nechushtan; Dmitry Kaluzhny; Eli Pikarsky; Ehud Razin
Transcription factor MITF regulates cardiac growth and hypertrophy.
The Journal of clinical investigation 2006;116(10):2673-81.
2006: Carmit Levy; Yu-Nee Lee; hovav nechushtan; Ora Schueler-Furman; Amir Sonnenblick; Shelley Hacohen; Ehud Razin
Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3.
Blood 2006;107(7):2839-45.
2006: Cellina Cohen-Saidon; Irit Carmi; Avishai Keren; Ehud Razin
Antiapoptotic function of Bcl-2 in mast cells is dependent on its association with heat shock protein 90beta.
Blood 2006;107(4):1413-20.
2005: Yu-Nee Lee; Ehud Razin
Nonconventional involvement of LysRS in the molecular mechanism of USF2 transcriptional activity in FcepsilonRI-activated mast cells.
Molecular and cellular biology 2005;25(20):8904-12.
2005: Amir Sonnenblick; Carmit Levy; Ehud Razin
Immunological trigger of mast cells by monomeric IgE: effect on microphthalmia transcription factor, STAT3 network of interactions.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1450-5.
2005: Cellina Cohen-Saidon; Ehud Razin
The involvement of Bcl-2 in mast cell apoptosis.
Novartis Foundation symposium 2005;271():191-5; discussion 195-9.
2004: Amir Sonnenblick; Carmit Levy; Ehud Razin
Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes.
Molecular and cellular biology 2004;24(24):10584-92.
2004: Yu-Nee Lee; Jan Tuckerman; hovav nechushtan; Gunter Schutz; Ehud Razin; Peter Angel
c-Fos as a regulator of degranulation and cytokine production in FcepsilonRI-activated mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2571-7.
2004: Yu-Nee Lee; hovav nechushtan; Navah Figov; Ehud Razin
The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FcepsilonRI-activated mast cells.
Immunity 2004;20(2):145-51.
2003: Carmit Levy; Amir Sonnenblick; Ehud Razin
Role played by microphthalmia transcription factor phosphorylation and its Zip domain in its transcriptional inhibition by PIAS3.
Molecular and cellular biology 2003;23(24):9073-80.
2003: Cellina Cohen-Saidon; hovav nechushtan; Shira Kahlon; Nadav Livni; Ahuva Nissim; Ehud Razin
A novel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival.
Blood 2003;102(7):2506-12.
2002: hovav nechushtan; Ehud Razin
The function of MITF and associated proteins in mast cells.
Molecular immunology 2002;38(16-18):1177-80.
2002: Carmit Levy; hovav nechushtan; Ehud Razin
A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor.
The Journal of biological chemistry 2002;277(3):1962-6.
2001: hovav nechushtan; Ehud Razin
Studies of different aspects of the role of protein kinase C in mast cells.
International archives of allergy and immunology 2001;124(1-3):130-2.
2000: hovav nechushtan; M Leitges; Cellina Cohen-Saidon; Gillian Kay; Ehud Razin
Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cbeta.
Blood 2000;95(5):1752-7.
1999: Ehud Razin; Z C Zhang; hovav nechushtan; Shahar Frenkel; Yu-Nee Lee; R Arudchandran; Juan Rivera
Suppression of microphthalmia transcriptional activity by its association with protein kinase C-interacting protein 1 in mast cells.
The Journal of biological chemistry 1999;274(48):34272-6.
1998: hovav nechushtan; Ehud Razin
Deciphering the early-response transcription factor networks in mast cells.
Immunology today 1998;19(10):441-4.
1998: Shahar Frenkel; Gillian Kay; hovav nechushtan; Ehud Razin
Nuclear translocation of upstream stimulating factor 2 (USF2) in activated mast cells: a possible role in their survival.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(6):2881-7.
1998: Z C Zhang; hovav nechushtan; Jasmine Jacob-Hirsch; D Avni; Oded Meyuhas; Ehud Razin
Growth-dependent and PKC-mediated translational regulation of the upstream stimulating factor-2 (USF2) mRNA in hematopoietic cells.
Oncogene 1998;16(6):763-9.
1997: M Ligumsky; V Kuperstein; hovav nechushtan; Z Zhang; Ehud Razin
Analysis of cytokine profile in human colonic mucosal Fc epsilonRI-positive cells by single cell PCR: inhibition of IL-3 expression in steroid-treated IBD patients.
FEBS letters 1997;413(3):436-40.
1997: hovav nechushtan; Z Zhang; Ehud Razin
Microphthalmia (mi) in murine mast cells: regulation of its stimuli-mediated expression on the translational level.
Blood 1997;89(8):2999-3008.
1996: hovav nechushtan; Ehud Razin
Regulation of mast cell growth and proliferation.
Critical reviews in oncology/hematology 1996;23(2):131-50.
1996: hovav nechushtan; H Soreq; V Kuperstein; S Tshori; Ehud Razin
Murine and human mast cell express acetylcholinesterase.
FEBS letters 1996;379(1):1-6.
1996: I Lewin; J Jacob-Hirsch; Z C Zang; V Kupershtein; Z Szallasi; Juan Rivera; Ehud Razin
Aggregation of the Fc epsilon RI in mast cells induces the synthesis of Fos-interacting protein and increases its DNA binding-activity: the dependence on protein kinase C-beta.
The Journal of biological chemistry 1996;271(3):1514-9.
1995: Ehud Razin; I Pecht; Juan Rivera
Signal transduction in the activation of mast cells and basophils.
Immunology today 1995;16(8):370-3.
1995: E Chaikin; I Hakeem; Ehud Razin
The incapability of interleukin-4 to induce AP-1 activity in murine mast cells.
International archives of allergy and immunology 1995;107(1-3):57-9.
1994: Ehud Razin; Z Szallasi; Marcelo G Kazanietz; P M Blumberg; Juan Rivera
Protein kinases C-beta and C-epsilon link the mast cell high-affinity receptor for IgE to the expression of c-fos and c-jun.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(16):7722-6.
1994: E Chaikin; I Hakeem; Ehud Razin
Enhancement of interleukin-3-dependent mast cell proliferation by suppression of c-jun expression.
The Journal of biological chemistry 1994;269(11):8498-503.
1993: I Lewin; hovav nechushtan; Q Ke; Ehud Razin
Regulation of AP-1 expression and activity in antigen-stimulated mast cells: the role played by protein kinase C and the possible involvement of Fos interacting protein.
Blood 1993;82(12):3745-51.
1993: A Ophir; Eduard Berenshtein; H J Ziltener; Ehud Razin
5-fluorouracil and mast cell precursors in mice.
Experimental hematology 1993;21(12):1558-62.
1993: D Baranes; I Lewin; Ehud Razin
Serum modulates mast cell responses to IgE antigen stimulation.
European journal of immunology 1993;23(1):291-4.
1991: D Baranes; Ehud Razin
Protein kinase C regulates proliferation of mast cells and the expression of the mRNAs of fos and jun proto-oncogenes during activation by IgE-Ag or calcium ionophore A23187.
Blood 1991;78(9):2354-64.
1991: Ehud Razin; K B Leslie; J W Schrader
Connective tissue mast cells in contact with fibroblasts express IL-3 mRNA. Analysis of single cells by polymerase chain reaction.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(3):981-7.
1990: E Chaikin; H J Ziltener; Ehud Razin
Protein kinase C plays an inhibitory role in interleukin 3- and interleukin 4-mediated mast cell proliferation.
The Journal of biological chemistry 1990;265(36):22109-16.
1990: Leon Gilead; Osaat Bibi; Ehud Razin
Fibroblasts induce heparin synthesis in chondroitin sulfate E containing human bone marrow-derived mast cells.
Blood 1990;76(6):1188-95.
1990: S Davidson; Leon Gilead; M Amira; H Ginsburg; Ehud Razin
Synthesis of chondroitin sulfate D and heparin proteoglycans in murine lymph node-derived mast cells. The dependence on fibroblasts.
The Journal of biological chemistry 1990;265(21):12324-30.
1990: P Bashkin; Ehud Razin; Amiram Eldor; Israel Vlodavsky
Degranulating mast cells secrete an endoglycosidase that degrades heparan sulfate in subendothelial extracellular matrix.
Blood 1990;75(11):2204-12.
1988: Rami Eliakim; Fanny Karmeli; Ehud Razin; Daniel Rachmilewitz
Role of platelet-activating factor in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine and prednisolone.
Gastroenterology 1988;95(5):1167-72.
1988: Yaacov Matzner; M Cohn; E Hyam; Ehud Razin; Z Fuks; Michael Buchanan; T A Haas; Israel Vlodavsky; Amiram Eldor
Generation of lipid neutrophil chemoattractant by irradiated bovine aortic endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(8):2681-5.
1988: Leon Gilead; E Rahamim; I Ziv; R Or; Ehud Razin
Cultured human bone marrow-derived mast cells, their similarities to cultured murine E-mast cells.
Immunology 1988;63(4):669-75.
1987: M Lerner; Amram Samuni; Ehud Razin
Stimulation of murine cultured mast cells under anaerobic conditions: inhibition of arachidonic acid release.
Immunology letters 1987;16(2):121-4.
1987: Leon Gilead; Nelly Livni; R Eliakim; M Ligumsky; A Fich; E Okon; D Rachmilewitz; Ehud Razin
Human gastric mucosal mast cells are chondroitin sulphate E-containing mast cells.
Immunology 1987;62(1):23-8.
1986: D Baranes; Fu-Tong Liu; Ehud Razin
Thrombin and IgE antigen induce formation of inositol phosphates by mouse E-mast cells.
FEBS letters 1986;206(1):64-8.
1986: D Baranes; Fu-Tong Liu; G Marx; M Shalit; Ehud Razin
Regulation of thrombin-induced mast cell degranulation by zinc and manganese.
Immunology letters 1986;12(2-3):95-9.
1986: R Eliakim; Leon Gilead; M Ligumsky; E Okon; D Rachmilewitz; Ehud Razin
Histamine and chondroitin sulfate E proteoglycan released by cultured human colonic mucosa: indication for possible presence of E mast cells.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(2):461-4.
1985: Ehud Razin; D Baranes; G Marx
Thrombin-mast cell interactions. Binding and cell activation.
Experimental cell research 1985;160(2):380-6.