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Mickie Bhatia

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Brendan McIntyre; Rami Mechael; Veronica Ramos-Mejia; Shravanti Rampalli; Guojun Sheng; Cantas Alev; Jong-Hee Lee; Mickie Bhatia
Gli3-mediated hedgehog inhibition in human pluripotent stem cells initiates and augments developmental programming of adult hematopoiesis.
Angelique Schnerch; Monica Graham; Borhane Guezguez; Jung Bok Lee; Mickie Bhatia
Human embryonic stem cell-derived hematopoietic cells maintain core epigenetic machinery of the polycomb group/Trithorax Group complexes distinctly from functional adult hematopoietic stem cells.
Se-Woong Oh; Mickie Bhatia; Jong-Ryul Ha; Sejin Jeon; Bora Kim; Min-Kyoung Kim; Jung Bok Lee; Ki-Hoan Nam; Goo Taeg Oh; Dae-Yong Kim
Peptidomimetic small-molecule compounds promoting cardiogenesis of stem cells.

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2013: Brendan McIntyre; Rami Mechael; Veronica Ramos-Mejia; Shravanti Rampalli; Guojun Sheng; Cantas Alev; Jong-Hee Lee; Mickie Bhatia
Gli3-mediated hedgehog inhibition in human pluripotent stem cells initiates and augments developmental programming of adult hematopoiesis.
Blood 2013;121(9):1543-52.
2013: Angelique Schnerch; Monica Graham; Borhane Guezguez; Jung Bok Lee; Mickie Bhatia
Human embryonic stem cell-derived hematopoietic cells maintain core epigenetic machinery of the polycomb group/Trithorax Group complexes distinctly from functional adult hematopoietic stem cells.
Stem cells and development 2013;22(1):73-89.
2012: Se-Woong Oh; Mickie Bhatia; Jong-Ryul Ha; Sejin Jeon; Bora Kim; Min-Kyoung Kim; Jung Bok Lee; Ki-Hoan Nam; Goo Taeg Oh; Dae-Yong Kim
Peptidomimetic small-molecule compounds promoting cardiogenesis of stem cells.
Archives of pharmacal research 2012;35(11):1979-88.
2012: Chantal Cerdan; Jung Bok Lee; Marilyne Levadoux-Martin; Brendan McIntyre; Rami Mechael; Jiabi Yang; Mickie Bhatia
Activin A promotes hematopoietic fated mesoderm development through upregulation of brachyury in human embryonic stem cells.
Stem cells and development 2012;21(15):2866-77.
2012: Shravanti Rampalli; Mickie Bhatia
Human pluripotency: a difficult state to make smart choices.
Cell cycle (Georgetown, Tex.) 2012;11(13):2411-2.
2012: Eleftherios Sachlos; Zoya Shapovalova; Michael R Trus; Anargyros Xenocostas; Eric D Brown; Tony J Collins; Aline Fiebig-Comyn; Daniela Fischer-Russell; Ronan Foley; Andrew O Giacomelli; Monica Graham; John A Hassell; Sarah Laronde; Brian Leber; Jung Bok Lee; Jong-Hee Lee; Marilyne Levadoux-Martin; Monika Malig; Jamie D McNicol; Ruth M Risueño; Jennifer Russell; Mickie Bhatia
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.
Cell 2012;149(6):1284-97.
2012: Tamra E Werbowetski-Ogilvie; Aline Fiebig-Comyn; Ludivine Coudière Morrison; Mickie Bhatia
In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation.
Stem cells (Dayton, Ohio) 2012;30(3):392-404.
2012: Ruth M Risueño; Eleftherios Sachlos; Eva Szabo; Seok-Ho Hong; Jung Bok Lee; Jong-Hee Lee; Mickie Bhatia
Inability of human induced pluripotent stem cell-hematopoietic derivatives to downregulate microRNAs in vivo reveals a block in xenograft hematopoietic regeneration.
Stem cells (Dayton, Ohio) 2012;30(2):131-9.
2011: T E Werbowetski-Ogilvie; S-H Hong; Jung Bok Lee; Marilyne Levadoux-Martin; C E Mills; Shravanti Rampalli; Angelique Schnerch; Mickie Bhatia
Evidence for the transmission of neoplastic properties from transformed to normal human stem cells.
Oncogene 2011;30(46):4632-44.
2011: Seok-Ho Hong; Jung Bok Lee; Jamie McNicol; Shravanti Rampalli; Tony Collins; Jonathan S Draper; Mickie Bhatia
Cell fate potential of human pluripotent stem cells is encoded by histone modifications.
Cell stem cell 2011;9(1):24-36.
2011: Ruth M Risueño; Anargyros Xenocostas; Clinton J V Campbell; Steve Dingwall; Brian Leber; Marilyne Levadoux-Martin; Mickie Bhatia
Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease.
Blood 2011;117(26):7112-20.
2011: Seok-Ho Hong; Jong-Hee Lee; Jung Bok Lee; Junfeng Ji; Mickie Bhatia
ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis.
Journal of cell science 2011;124(Pt 9):1445-52.
2011: Kristin Hope; Mickie Bhatia
Clonal interrogation of stem cells.
Nature methods 2011;8(4 Suppl):S36-40.
2011: Junfeng Ji; Ruth M Risueño; Seokho Hong; David Allan; Patty Rosten; Keith Humphries; Mickie Bhatia
Brief report: ectopic expression of NUP98-HOXA10 augments erythroid differentiation of human embryonic stem cells.
Stem cells (Dayton, Ohio) 2011;29(4):736-41.
2010: Eva Szabo; Shravanti Rampalli; Ruth M Risueño; Angelique Schnerch; Ryan Mitchell; Aline Fiebig-Comyn; Marilyne Levadoux-Martin; Mickie Bhatia
Direct conversion of human fibroblasts to multilineage blood progenitors.
Nature 2010;468(7323):521-6.
2010: morag helen stewart; Sean C Bendall; Marilyne Levadoux-Martin; Mickie Bhatia
Clonal tracking of hESCs reveals differential contribution to functional assays.
Nature methods 2010;7(11):917-22.
2010: Clinton J V Campbell; Jung Bok Lee; Marilyne Levadoux-Martin; Tracy Wynder; Anargyros Xenocostas; Brian Leber; Mickie Bhatia
The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity.
Blood 2010;116(9):1433-42.
2010: Seok-Ho Hong; Tamra Werbowetski-Ogilvie; Veronica Ramos-Mejia; Jung Bok Lee; Mickie Bhatia
Multiparameter comparisons of embryoid body differentiation toward human stem cell applications.
Stem cell research 2010;5(2):120-30.
2010: Mickie Bhatia
Developmental biology. Microenvironment mimicry.
Science (New York, N.Y.) 2010;329(5995):1024-5.
2010: Jennifer J Trowbridge; Borhane Guezguez; Randall T Moon; Mickie Bhatia
Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity.
Stem cells (Dayton, Ohio) 2010;28(8):1379-89.
2010: Duane Moogk; morag helen stewart; Darik Gamble; Mickie Bhatia; Eric Jervis
Human ESC colony formation is dependent on interplay between self-renewing hESCs and unique precursors responsible for niche generation.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2010;77(4):321-7.
2010: Angelique Schnerch; Chantal Cerdan; Mickie Bhatia
Distinguishing between mouse and human pluripotent stem cell regulation: the best laid plans of mice and men.
Stem cells (Dayton, Ohio) 2010;28(3):419-30.
2010: Chantal Cerdan; Mickie Bhatia
Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells.
The International journal of developmental biology 2010;54(6-7):955-63.
2009: Mickie Bhatia
Mickie Bhatia: Embryonic stem cells come of age.
The Journal of experimental medicine 2009;206(10):2056-7.
2009: Akitsu Hotta; Aaron Y L Cheung; Natalie Farra; Kausalia Vijayaragavan; Cheryle A Séguin; Jonathan S Draper; Peter Pasceri; Irina A Maksakova; Dixie L Mager; Janet Rossant; Mickie Bhatia; James Ellis
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency.
Nature methods 2009;6(5):370-6.
2009: Kausalia Vijayaragavan; Eva Szabo; Marc Bossé; Veronica Ramos-Mejia; Randall T Moon; Mickie Bhatia
Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells.
Cell stem cell 2009;4(3):248-62.
2009: Sean C Bendall; Chris Hughes; J Larry Campbell; morag helen stewart; Paula Pittock; Suya Liu; Eric Bonneil; Pierre Thibault; Mickie Bhatia; Gilles Lajoie
An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture.
Molecular & cellular proteomics : MCP 2009;8(3):421-32.
2009: Junfeng Ji; Tamra E Werbowetski-Ogilvie; Bonan Zhong; Seok-Ho Hong; Mickie Bhatia
Pluripotent transcription factors possess distinct roles in normal versus transformed human stem cells.
PloS one 2009;4(11):e8065.
2009: Tamra E Werbowetski-Ogilvie; Marc Bossé; morag helen stewart; Angelique Schnerch; Veronica Ramos-Mejia; Anne Rouleau; Tracy Wynder; Mary-Jo Smith; Steve Dingwall; Tim Carter; Christopher Williams; Charles Harris; Joanna Dolling; Christopher Wynder; Douglas R Boreham; Mickie Bhatia
Characterization of human embryonic stem cells with features of neoplastic progression.
Nature biotechnology 2009;27(1):91-7.
2008: Junfeng Ji; Kausalia Vijayaragavan; Marc Bosse; Pablo Menendez; Katja Weisel; Mickie Bhatia
OP9 stroma augments survival of hematopoietic precursors and progenitors during hematopoietic differentiation from human embryonic stem cells.
Stem cells (Dayton, Ohio) 2008;26(10):2485-95.
2008: Bijan K Dey; Leanne Stalker; Angelique Schnerch; Mickie Bhatia; Joyce Taylor-Papidimitriou; Christopher Wynder
The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation.
Molecular and cellular biology 2008;28(17):5312-27.
2008: Sean C Bendall; Chris Hughes; morag helen stewart; Bradley Doble; Mickie Bhatia; Gilles Lajoie
Prevention of amino acid conversion in SILAC experiments with embryonic stem cells.
Molecular & cellular proteomics : MCP 2008;7(9):1587-97.
2008: Tamra E Werbowetski-Ogilvie; Mickie Bhatia
Pluripotent human stem cell lines: what we can learn about cancer initiation.
Trends in molecular medicine 2008;14(8):323-32.
2008: morag helen stewart; Sean C Bendall; Mickie Bhatia
Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency.
Journal of molecular medicine (Berlin, Germany) 2008;86(8):875-86.
2008: Clint Campbell; Ruth M Risueno; Simona Salati; Borhane Guezguez; Mickie Bhatia
Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects.
Current opinion in hematology 2008;15(4):319-25.
2008: Simona Salati; Ruth M Risueno; Mickie Bhatia
Targeting LSCs: powering an old tool.
Blood 2008;111(12):5423-4.
2008: Sean C Bendall; morag helen stewart; Mickie Bhatia
Human embryonic stem cells: lessons from stem cell niches in vivo.
Regenerative medicine 2008;3(3):365-76.
2008: Borhane Guezguez; Mickie Bhatia
Transplantation of human hematopoietic repopulating cells: mechanisms of regeneration and differentiation using human-mouse xenografts.
Current opinion in organ transplantation 2008;13(1):44-52.
2007: Chantal Cerdan; Seok Ho Hong; Mickie Bhatia
Formation and hematopoietic differentiation of human embryoid bodies by suspension and hanging drop cultures.
Current protocols in stem cell biology 2007;Chapter 1():Unit 1D.2.
2007: Sean C Bendall; morag helen stewart; Pablo Menendez; Dustin George; Kausalia Vijayaragavan; Tamra Werbowetski-Ogilvie; Veronica Ramos-Mejia; Anne Rouleau; Jiabi Yang; Marc Bossé; Gilles Lajoie; Mickie Bhatia
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro.
Nature 2007;448(7157):1015-21.
2007: Kausalia Vijayaragavan; Mickie Bhatia
Early cardiac development: a Wnt beat away.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9549-50.
2007: Mickie Bhatia
Hematopoiesis from human embryonic stem cells.
Annals of the New York Academy of Sciences 2007;1106():219-22.
2007: Mickie Bhatia
Hematopoietic development from human embryonic stem cells.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2007;():11-6.
2006: Chantal Cerdan; Sean C Bendall; Lisheng Wang; morag helen stewart; Tamra Werbowetski; Mickie Bhatia
Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells.
Nature medicine 2006;12(10):1113-4; author reply 1115.
2006: morag helen stewart; Marc Bossé; Kristin Chadwick; Pablo Menendez; Sean C Bendall; Mickie Bhatia
Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment.
Nature methods 2006;3(10):807-15.
2006: Jennifer J Trowbridge; Randall T Moon; Mickie Bhatia
Hematopoietic stem cell biology: too much of a Wnt thing.
Nature immunology 2006;7(10):1021-3.
2006: Jennifer J Trowbridge; Matthew P Scott; Mickie Bhatia
Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):14134-9.
2006: Chantal Cerdan; Mickie Bhatia
[Human embryonic stem cell and haematopoiesis: comparison with the mouse].
Médecine sciences : M/S 2006;22(8-9):705-7.
2006: Pablo Menendez; Lisheng Wang; Chantal Cerdan; Mickie Bhatia
Retroviral transduction of hematopoietic progenitors derived from human embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2006;331():201-20.
2006: Lisheng Wang; Chantal Cerdan; Pablo Menendez; Mickie Bhatia
Derivation and characterization of hematopoietic cells from human embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2006;331():179-200.
2006: Jennifer J Trowbridge; Anargyros Xenocostas; Randall T Moon; Mickie Bhatia
Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation.
Nature medicine 2006;12(1):89-98.
2005: Krysta Levac; Pablo Menendez; Mickie Bhatia
Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/beta2m(-/-) mice.
Experimental hematology 2005;33(11):1417-26.
2005: Matthew A Martin; Mickie Bhatia
Analysis of the human fetal liver hematopoietic microenvironment.
Stem cells and development 2005;14(5):493-504.
2005: Michael Rosu-Myles; Erin Stewart; Jennifer Trowbridge; Caryn Y Ito; Peter Zandstra; Mickie Bhatia
A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis.
Journal of cell science 2005;118(Pt 19):4343-52.
2005: Lisheng Wang; Pablo Menendez; Chantal Cerdan; Mickie Bhatia
Hematopoietic development from human embryonic stem cell lines.
Experimental hematology 2005;33(9):987-96.
2005: Pablo Menendez; Lisheng Wang; Mickie Bhatia
Genetic manipulation of human embryonic stem cells: a system to study early human development and potential therapeutic applications.
Current gene therapy 2005;5(4):375-85.
2005: David S Allan; Lisa Gallacher; Michael Keeney; Mickie Bhatia; Ian H Chin-Yee; A Xenocostas
Undetectable leukemic blasts and absence of NOD/SCID leukemia-initiating cells in cord blood from a case of maternal AML.
Bone marrow transplantation 2005;36(3):269-70.
2005: Lisheng Wang; Li Li; Pablo Menendez; Chantal Cerdan; Mickie Bhatia
Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development.
Blood 2005;105(12):4598-603.
2005: Mickie Bhatia
Derivation of the hematopoietic stem cell compartment from human embryonic stem cell lines.
Annals of the New York Academy of Sciences 2005;1044():24-8.
2005: Lisheng Wang; Pablo Menendez; Farbod Shojaei; Li Li; Frederick Mazurier; John E Dick; Chantal Cerdan; Krysta Levac; Mickie Bhatia
Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression.
The Journal of experimental medicine 2005;201(10):1603-14.
2005: Farbod Shojaei; Jennifer Trowbridge; Lisa Gallacher; Lou Yuefei; David Goodale; Francis Karanu; Krysta Levac; Mickie Bhatia
Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior.
Developmental cell 2005;8(5):651-63.
2005: D S Allan; K E Jay; Mickie Bhatia
Hematopoietic capacity of adult human skeletal muscle is negligible.
Bone marrow transplantation 2005;35(7):663-6.
2005: Kristin Chadwick; Farbod Shojaei; Lisa Gallacher; Mickie Bhatia
Smad7 alters cell fate decisions of human hematopoietic repopulating cells.
Blood 2005;105(5):1905-15.
2005: Krysta Levac; Francis Karanu; Mickie Bhatia
Identification of growth factor conditions that reduce ex vivo cord blood progenitor expansion but do not alter human repopulating cell function in vivo.
Haematologica 2005;90(2):166-72.
2005: Pablo Menendez; Clara Bueno; Lisheng Wang; Mickie Bhatia
Human embryonic stem cells: potential tool for achieving immunotolerance?
Stem cell reviews 2005;1(2):151-8.
2004: Pablo Menendez; Lisheng Wang; Kristin Chadwick; Li Li; Mickie Bhatia
Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45(neg)PFV hemogenic precursors.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(6):1109-20.
2004: Karen E Jay; Anne Rouleau; Tully Underhill; Mickie Bhatia
Identification of a novel population of human cord blood cells with hema-topoietic and chondrocytic potential.
Cell research 2004;14(4):268-82.
2004: Lisheng Wang; Li Li; Farbod Shojaei; Krysta Levac; Chantal Cerdan; Pablo Menendez; Tanya Martin; Anne Rouleau; Mickie Bhatia
Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties.
Immunity 2004;21(1):31-41.
2004: Chantal Cerdan; Anne Rouleau; Mickie Bhatia
VEGF-A165 augments erythropoietic development from human embryonic stem cells.
Blood 2004;103(7):2504-12.
2004: Farbod Shojaei; Lisa Gallacher; Mickie Bhatia
Differential gene expression of human stem progenitor cells derived from early stages of in utero human hematopoiesis.
Blood 2004;103(7):2530-40.
2004: Li Li; Miren L Baroja; Anish Majumdar; Kristin Chadwick; Anne Rouleau; Lisa Gallacher; Iris Ferber; Jane Lebkowski; Tanya Martin; Joaquín Madrenas; Mickie Bhatia
Human embryonic stem cells possess immune-privileged properties.
Stem cells (Dayton, Ohio) 2004;22(4):448-56.
2003: David A Hess; Francis Karanu; Krysta Levac; Lisa Gallacher; Mickie Bhatia
Coculture and transplant of purified CD34(+)Lin(-) and CD34(-)Lin(-) cells reveals functional interaction between repopulating hematopoietic stem cells.
Leukemia 2003;17(8):1613-25.
2003: Kristin Chadwick; Lisheng Wang; Li Li; Pablo Menendez; Barbara Murdoch; Anne Rouleau; Mickie Bhatia
Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells.
Blood 2003;102(3):906-15.
2003: Francis Karanu; L Yuefei; Lisa Gallacher; Seiji Sakano; Mickie Bhatia
Differential response of primitive human CD34- and CD34+ hematopoietic cells to the Notch ligand Jagged-1.
Leukemia 2003;17(7):1366-74.
2003: David Hess; Li Li; Matthew Martin; Seiji Sakano; David Hill; Brenda Strutt; Sandra Thyssen; Douglas A Gray; Mickie Bhatia
Bone marrow-derived stem cells initiate pancreatic regeneration.
Nature biotechnology 2003;21(7):763-70.
2003: Barbara Murdoch; Kristin Chadwick; Matthew Martin; Farbod Shojaei; Kavita V Shah; Lisa Gallacher; Randall T Moon; Mickie Bhatia
Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3422-7.
2003: Michael Rosu-Myles; Mickie Bhatia
SDF-1 enhances the expansion and maintenance of highly purified human hematopoietic progenitors.
The hematology journal : the official journal of the European Haematology Association / EHA 2003;4(2):137-45.
2003: Mickie Bhatia
The ultimate source of human hematopoietic stem cells: thinking outside the marrow.
Cloning and stem cells 2003;5(1):89-97.
2002: Ian H Chin-Yee; Michael Keeney; A Keith Stewart; Andrew R Belch; I Bence-Buckler; Stephen Couban; Kang Howson-Jan; M Rubinger; D Stewart; R Sutherland; V Paragamian; Mickie Bhatia; Ronan Foley
Optimising parameters for peripheral blood leukapheresis after r-metHuG-CSF (filgrastim) and r-metHuSCF (ancestim) in patients with multiple myeloma: a temporal analysis of CD34(+) absolute counts and subsets.
Bone marrow transplantation 2002;30(12):851-60.
2002: Karen E Jay; Lisa Gallacher; Mickie Bhatia
Emergence of muscle and neural hematopoiesis in humans.
Blood 2002;100(9):3193-202.
2002: David A Hess; Krysta Levac; Francis Karanu; Michael Rosu-Myles; Martin J White; Lisa Gallacher; Barbara Murdoch; Michael Keeney; Pamela Ottowski; Ronan Foley; Ian H Chin-Yee; Mickie Bhatia
Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor.
Blood 2002;100(3):869-78.
2002: Jannine Wilpshaar; Mickie Bhatia; Humphrey H H Kanhai; Robert Breese; Doug K Heilman; Cynthia S Johnson; J H Frederik Falkenburg; Edward F Srour
Engraftment potential of human fetal hematopoietic cells in NOD/SCID mice is not restricted to mitotically quiescent cells.
Blood 2002;100(1):120-7.
2002: David S Allan; Michael Keeney; Kang Howson-Jan; J Popma; K Weir; Mickie Bhatia; D Robert Sutherland; Ian H Chin-Yee
Number of viable CD34(+) cells reinfused predicts engraftment in autologous hematopoietic stem cell transplantation.
Bone marrow transplantation 2002;29(12):967-72.
2002: Barbara Murdoch; Lisa Gallacher; Kristin Chadwick; Fraser Fellows; Mickie Bhatia
Human embryonic-derived hematopoietic repopulating cells require distinct factors to sustain in vivo repopulating function.
Experimental hematology 2002;30(6):598-605.
2002: Barbara Murdoch; Lisa Gallacher; Kristin Chadwick; Mickie Bhatia
Characterization of retroviral gene transfer into highly purified human CD34(-) cells with primitive hematopoietic capacity.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(5 Pt 1):635-43.
2001: Mickie Bhatia
AC133 expression in human stem cells.
Leukemia 2001;15(11):1685-8.
2001: Barbara Murdoch; Lisa Gallacher; Christian Awaraji; David A Hess; Michael Keeney; K Jay; Kristin Chadwick; S R Fowley; Kang Howson-Jan; Ian H Chin-Yee; D Wu; E D Srour; Fraser Fellows; Mickie Bhatia
Circulating hematopoietic stem cells serve as novel targets for in utero gene therapy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1628-30.
2001: Francis Karanu; Barbara Murdoch; Tomoyuki Miyabayashi; M Ohno; M Koremoto; Lisa Gallacher; D Wu; A Itoh; Seiji Sakano; Mickie Bhatia
Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells.
Blood 2001;97(7):1960-7.
2001: G Bhardwaj; Barbara Murdoch; D Wu; Darren P Baker; Kevin P Williams; Kristin Chadwick; Leona E Ling; Francis Karanu; Mickie Bhatia
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation.
Nature immunology 2001;2(2):172-80.
2000: Michael Rosu-Myles; Lisa Gallacher; Barbara Murdoch; David A Hess; Michael Keeney; D Kelvin; L Dale; S S Ferguson; D Wu; Fraser Fellows; Mickie Bhatia
The human hematopoietic stem cell compartment is heterogeneous for CXCR4 expression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14626-31.
2000: Francis Karanu; Barbara Murdoch; Lisa Gallacher; DM Wu; M Koremoto; Seiji Sakano; Mickie Bhatia
The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells.
The Journal of experimental medicine 2000;192(9):1365-72.
2000: Lisa Gallacher; Barbara Murdoch; D Wu; Francis Karanu; Fraser Fellows; Mickie Bhatia
Identification of novel circulating human embryonic blood stem cells.
Blood 2000;96(5):1740-7.
2000: Jian-Xin Gao; Jian Zhang; Christian Awaraji; Mickie Bhatia; Anthony M Jevnikar; B Singh; D Bell; Terry L Delovitch
Preferential proliferation and differentiation of double-positive thymocytes into CD8(+) single-positive thymocytes in a novel cell culture medium.
Cellular immunology 2000;202(1):41-53.
2000: Lisa Gallacher; Barbara Murdoch; DM Wu; Francis Karanu; Michael Keeney; Mickie Bhatia
Isolation and characterization of human CD34(-)Lin(-) and CD34(+)Lin(-) hematopoietic stem cells using cell surface markers AC133 and CD7.
Blood 2000;95(9):2813-20.
2000: Michael Rosu-Myles; MH Khandaker; DM Wu; Michael Keeney; S R Foley; Kang Howson-Jan; Ian Chin Yee; Fraser Fellows; D Kelvin; Mickie Bhatia
Characterization of chemokine receptors expressed in primitive blood cells during human hematopoietic ontogeny.
Stem cells (Dayton, Ohio) 2000;18(5):374-81.
1999: Mickie Bhatia; D Bonnet; D Wu; Barbara Murdoch; J Wrana; Lisa Gallacher; John E Dick
Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells.
The Journal of experimental medicine 1999;189(7):1139-48.
1999: D Bonnet; Mickie Bhatia; Jean C Y Wang; U Kapp; John E Dick
Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice.
Bone marrow transplantation 1999;23(3):203-9.
1998: U Kapp; Mickie Bhatia; D Bonnet; Barbara Murdoch; John E Dick
Treatment of non-obese diabetic (NOD)/Severe-combined immunodeficient mice (SCID) with flt3 ligand and interleukin-7 impairs the B-lineage commitment of repopulating cells after transplantation of human hematopoietic cells.
Blood 1998;92(6):2024-31.
1998: Mickie Bhatia; D Bonnet; Barbara Murdoch; Olga I Gan; John E Dick
A newly discovered class of human hematopoietic cells with SCID-repopulating activity.
Nature medicine 1998;4(9):1038-45.
1997: Mickie Bhatia; D Bonnet; U Kapp; Jean C Y Wang; Barbara Murdoch; John E Dick
Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture.
The Journal of experimental medicine 1997;186(4):619-24.
1997: Mickie Bhatia; Jean C Y Wang; U Kapp; D Bonnet; John E Dick
Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5320-5.
1997: John E Dick; Mickie Bhatia; Olga I Gan; U Kapp; Jean C Y Wang
Assay of human stem cells by repopulation of NOD/SCID mice.
Stem cells (Dayton, Ohio) 1997;15 Suppl 1():199-203; discussion 204-7.
1996: A Larochelle; J Vormoor; Helmut Hanenberg; Jean C Y Wang; Mickie Bhatia; Tsvee Lapidot; T Moritz; Barbara Murdoch; X L Xiao; I Kato; David A Williams; John E Dick
Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy.
Nature medicine 1996;2(12):1329-37.