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Venkat Reddy

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Dongli Yang; Susan G Elner; Li-Ren Lin; Venkat N Reddy; Howard R Petty; Victor M Elner
Association of superoxide anions with retinal pigment epithelial cell apoptosis induced by mononuclear phagocytes.
Huan Wang; Junyuan Gao; Xiurong Sun; Francisco J Martinez-Wittinghan; Leping Li; Kulandaiappan Varadaraj; Melissa Farrell; Venkat N Reddy; Thomas W White; Richard T Mathias
The effects of GPX-1 knockout on membrane transport and intracellular homeostasis in the lens.
Masahiko Shibuya; Haru Okamoto; Takehiro Nozawa; Jun Utsumi; Venkat N Reddy; Hirotoshi Echizen; Yasuhiko Tanaka; Takeshi Iwata
Proteomic and transcriptomic analyses of retinal pigment epithelial cells exposed to REF-1/TFPI-2.

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All Publications

2009: Dongli Yang; Susan G Elner; Li-Ren Lin; Venkat N Reddy; Howard R Petty; Victor M Elner
Association of superoxide anions with retinal pigment epithelial cell apoptosis induced by mononuclear phagocytes.
Investigative ophthalmology & visual science 2009;50(10):4998-5005.
2009: Huan Wang; Junyuan Gao; Xiurong Sun; Francisco J Martinez-Wittinghan; Leping Li; Kulandaiappan Varadaraj; Melissa Farrell; Venkat N Reddy; Thomas W White; Richard T Mathias
The effects of GPX-1 knockout on membrane transport and intracellular homeostasis in the lens.
The Journal of membrane biology 2009;227(1):25-37.
2007: Masahiko Shibuya; Haru Okamoto; Takehiro Nozawa; Jun Utsumi; Venkat N Reddy; Hirotoshi Echizen; Yasuhiko Tanaka; Takeshi Iwata
Proteomic and transcriptomic analyses of retinal pigment epithelial cells exposed to REF-1/TFPI-2.
Investigative ophthalmology & visual science 2007;48(2):516-21.
2006: Claudio Bucolo; Filippo Drago; Li-Ren Lin; Venkat N Reddy
Sigma receptor ligands protect human retinal cells against oxidative stress.
Neuroreport 2006;17(3):287-91.
2005: Emiko Kasahara; Li-Ren Lin; Ye-Shih Ho; Venkat N Reddy
SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration.
Investigative ophthalmology & visual science 2005;46(9):3426-34.
2005: Claudio Bucolo; Filippo Drago; Li-Ren Lin; Venkat N Reddy
Neuroactive steroids protect retinal pigment epithelium against oxidative stress.
Neuroreport 2005;16(11):1203-7.
2005: Hideaki Oharazawa; Nobuhiro Ibaraki; Kunitoshi Ohara; Venkat N Reddy
Inhibitory effects of Arg-Gly-Asp (RGD) peptide on cell attachment and migration in a human lens epithelial cell line.
Ophthalmic research 2005;37(4):191-6.
2004: Venkat N Reddy; E Kasahara; M Hiraoka; Li-Ren Lin; Ye-Shih Ho
Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium.
Experimental eye research 2004;79(6):859-68.
2004: Carla Marques; Paulo Pereira; Allen Taylor; Jack N Liang; Venkat N Reddy; Luke I Szweda; Fu Shang
Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1424-6.
2004: Marc Kantorow; John Hawse; Tracy L Cowell; Sonia Benhamed; Gresin O Pizarro; Venkat N Reddy; J Fielding Hejtmancik
Methionine sulfoxide reductase A is important for lens cell viability and resistance to oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9654-9.
2004: Katherine I Oravecz-Wilson; Mark J Kiel; Lina Li; Dinesh Rao; Djenann Saint-Dic; Priti D Kumar; Melissa M Provot; Kurt D Hankenson; Venkat N Reddy; Andrew P Lieberman; Sean J Morrison; Theodora S Ross
Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects and cataracts.
Human molecular genetics 2004;13(8):851-67.
2004: Yasuhiko Tanaka; Jun Utsumi; Mizuo Matsui; Tetsuo Sudo; Noriko Nakamura; Masato Mutoh; Akemi Kajita; Saburo Sone; Kazuteru Kigasawa; Masahiko Shibuya; Venkat N Reddy; Qiang Zhang; Takeshi Iwata
Purification, molecular cloning, and expression of a novel growth-promoting factor for retinal pigment epithelial cells, REF-1/TFPI-2.
Investigative ophthalmology & visual science 2004;45(1):245-52.
2003: Hironori Matsui; Li-Ren Lin; Ye-Shih Ho; Venkat N Reddy
The effect of up- and downregulation of MnSOD enzyme on oxidative stress in human lens epithelial cells.
Investigative ophthalmology & visual science 2003;44(8):3467-75.
2003: Rupalatha Maddala; Venkat N Reddy; David L Epstein; Vasantha Rao
Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells.
Molecular vision 2003;9():329-36.
2003: Sumanta Goswami; Nancy L Sheets; Jiri Zavadil; Bharesh K Chauhan; Erwin P Bottinger; Venkat N Reddy; Marc Kantorow; Ales Cvekl
Spectrum and range of oxidative stress responses of human lens epithelial cells to H2O2 insult.
Investigative ophthalmology & visual science 2003;44(5):2084-93.
2003: Eri Kubo; Dhirendra P Singh; Nigar Fatma; Toshimichi Shinohara; Peggy Zelenka; Venkat N Reddy; Leo T Chylack
Cellular distribution of lens epithelium-derived growth factor (LEDGF) in the rat eye: loss of LEDGF from nuclei of differentiating cells.
Histochemistry and cell biology 2003;119(4):289-99.
2003: John Hawse; Jonathan R Cumming; Brian Oppermann; Nancy L Sheets; Venkat N Reddy; Marc Kantorow
Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses.
Investigative ophthalmology & visual science 2003;44(2):672-9.
2002: Frank J Giblin; Victor R Leverenz; Vanita A Padgaonkar; Nalin J Unakar; Loan Dang; Li-Ren Lin; Marjorie F Lou; Venkat N Reddy; Douglas Borchman; James P Dillon
UVA light in vivo reaches the nucleus of the guinea pig lens and produces deleterious, oxidative effects.
Experimental eye research 2002;75(4):445-58.
2002: Hua Xiang; Juan Wang; Yingwei Mao; Mingyao Liu; Venkat N Reddy; David Wan-Cheng Li
Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway.
Oncogene 2002;21(23):3784-91.
2001: Venkat N Reddy; Frank J Giblin; Li-Ren Lin; Loan Dang; Nalin J Unakar; David C Musch; Daniel L Boyle; Larry Takemoto; Ye-Shih Ho; T Knoernschild; A Juenemann; Elke Lütjen-Drecoll
Glutathione peroxidase-1 deficiency leads to increased nuclear light scattering, membrane damage, and cataract formation in gene-knockout mice.
Investigative ophthalmology & visual science 2001;42(13):3247-55.
2001: H Matsui; Li-Ren Lin; Dhirendra P Singh; T Shinohara; Venkat N Reddy
Lens epithelium-derived growth factor: increased survival and decreased DNA breakage of human RPE cells induced by oxidative stress.
Investigative ophthalmology & visual science 2001;42(12):2935-41.
2001: Rupalatha Maddala; Venkat N Reddy; P Vasantha Rao
Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases.
Investigative ophthalmology & visual science 2001;42(11):2610-5.
2001: Y Wen; Nobuhiro Ibaraki; Venkat N Reddy; G Sachs
Functional analysis of the promoter and chromosomal localization for human LEP503, a novel lens epithelium gene.
Gene 2001;269(1-2):61-71.
2001: S Machida; P Chaudhry; T Shinohara; Dhirendra P Singh; Venkat N Reddy; Leo T Chylack; Paul Sieving; Ronald A Bush
Lens epithelium-derived growth factor promotes photoreceptor survival in light-damaged and RCS rats.
Investigative ophthalmology & visual science 2001;42(5):1087-95.
2000: Vanita A Padgaonkar; Victor R Leverenz; K E Fowler; Venkat N Reddy; Frank J Giblin
The effects of hyperbaric oxygen on the crystallins of cultured rabbit lenses: a possible catalytic role for copper.
Experimental eye research 2000;71(4):371-83.
2000: Douglas Borchman; Frank J Giblin; Victor R Leverenz; Venkat N Reddy; Li-Ren Lin; M Cecilia Yappert; Daxin Tang; L Li
Impact of aging and hyperbaric oxygen in vivo on guinea pig lens lipids and nuclear light scatter.
Investigative ophthalmology & visual science 2000;41(10):3061-73.
2000: Venkat N Reddy
A forty-two year voyage through vision research.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2000;16(2):97-107.
2000: Dhirendra P Singh; N Ohguro; T Kikuchi; T Sueno; Venkat N Reddy; K Yuge; Leo T Chylack; Toshimichi Shinohara
Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts.
Biochemical and biophysical research communications 2000;267(1):373-81.
1999: Hideaki Oharazawa; Nobuhiro Ibaraki; Li-Ren Lin; Venkat N Reddy
The effects of extracellular matrix on cell attachment, proliferation and migration in a human lens epithelial cell line.
Experimental eye research 1999;69(6):603-10.
1999: Y Wang; H He; J. SAMUEL ZIGLER; Takeshi Iwata; Nobuhiro Ibaraki; Venkat N Reddy; Deborah A Carper
bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line.
Experimental cell research 1999;249(1):123-30.
1999: Vanita A Padgaonkar; Li-Ren Lin; Victor R Leverenz; A Rinke; Venkat N Reddy; Frank J Giblin
Hyperbaric oxygen in vivo accelerates the loss of cytoskeletal proteins and MIP26 in guinea pig lens nucleus.
Experimental eye research 1999;68(4):493-504.
1999: Takeshi Iwata; Sanai Sato; J Jimenez; MH McGowan; Maria Moroni; A Dey; Nobuhiro Ibaraki; Venkat N Reddy; Deborah A Carper
Osmotic response element is required for the induction of aldose reductase by tumor necrosis factor-alpha.
The Journal of biological chemistry 1999;274(12):7993-8001.
1998: Nobuhiro Ibaraki; S C Chen; Li-Ren Lin; H Okamoto; J M Pipas; Venkat N Reddy
Human lens epithelial cell line.
Experimental eye research 1998;67(5):577-85.
1998: H Sasaki; Li-Ren Lin; T Yokoyama; M D Sevilla; Venkat N Reddy; Frank J Giblin
TEMPOL protects against lens DNA strand breaks and cataract in the x-rayed rabbit.
Investigative ophthalmology & visual science 1998;39(3):544-52.
1998: Venkat N Reddy; Frank J Giblin; Li-Ren Lin; B Chakrapani
The effect of aqueous humor ascorbate on ultraviolet-B-induced DNA damage in lens epithelium.
Investigative ophthalmology & visual science 1998;39(2):344-50.
1997: PV Rao; W Gerald Robison; Frederick A Bettelheim; Li-Ren Lin; Venkat N Reddy; J. SAMUEL ZIGLER
Role of small GTP-binding proteins in lovastatin-induced cataracts.
Investigative ophthalmology & visual science 1997;38(11):2313-21.
1997: Nobuhiro Ibaraki; Li-Ren Lin; Loan Dang; Venkat N Reddy; Dhirendra P Singh; T Sueno; Leo T Chylack; Toshimichi Shinohara
Anti-beta-crystallin antibodies (mouse) or sera from humans with age-related cataract are cytotoxic for lens epithelial cells in culture.
Experimental eye research 1997;64(2):229-38.
1997: Venkat N Reddy; Li-Ren Lin; Ye-Shih Ho; J L Magnenat; Nobuhiro Ibaraki; Frank J Giblin; Loan Dang
Peroxide-induced damage in lenses of transgenic mice with deficient and elevated levels of glutathione peroxidase.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde 1997;211(3):192-200.
1996: Nobuhiro Ibaraki; Li-Ren Lin; Venkat N Reddy
A study of growth factor receptors in human lens epithelial cells and their relationship to fiber differentiation.
Experimental eye research 1996;63(6):683-92.
1995: Nobuhiro Ibaraki; Li-Ren Lin; Venkat N Reddy
Effects of growth factors on proliferation and differentiation in human lens epithelial cells in early subculture.
Investigative ophthalmology & visual science 1995;36(11):2304-12.
1995: A Yoshida; N Pozdnyakov; Loan Dang; S M Orselli; Venkat N Reddy; Ari Sitaramayya
Nitric oxide synthesis in retinal photoreceptor cells.
Visual neuroscience 1995;12(3):493-500.
1995: Frank J Giblin; Vanita A Padgaonkar; Victor R Leverenz; Li-Ren Lin; Marjorie F Lou; Nalin J Unakar; Loan Dang; J E Dickerson; Venkat N Reddy
Nuclear light scattering, disulfide formation and membrane damage in lenses of older guinea pigs treated with hyperbaric oxygen.
Experimental eye research 1995;60(3):219-35.
1995: B Chakrapani; S Yedavally; Victor R Leverenz; Frank J Giblin; Venkat N Reddy
Simultaneous measurement of reduced and oxidized glutathione in human aqueous humor and cataracts by electrochemical detection.
Ophthalmic research 1995;27 Suppl 1():69-77.
1994: Barkur S Shastry; Venkat N Reddy
Studies on congenital hereditary cataract and microphthalmia of the miniature schnauzer dog.
Biochemical and biophysical research communications 1994;203(3):1663-7.
1994: C Bucolo; Li-Ren Lin; Loan Dang; Frank J Giblin; Venkat N Reddy
The effect of ganglioside on oxidation-induced permeability changes in lens and in epithelial cells of lens and retina.
Experimental eye research 1994;58(6):697-704.
1994: T Yokoyama; H Sasaki; Frank J Giblin; Venkat N Reddy
A physiological level of ascorbate inhibits galactose cataract in guinea pigs by decreasing polyol accumulation in the lens epithelium: a dehydroascorbate-linked mechanism.
Experimental eye research 1994;58(2):207-18.
1994: Vanita A Padgaonkar; Frank J Giblin; Victor R Leverenz; Li-Ren Lin; Venkat N Reddy
Studies of H2O2-Induced Effects on Cultured Bovine Trabecular Meshwork Cells.
Journal of glaucoma 1994;3(2):123-31.
1993: S Sato; Li-Ren Lin; Venkat N Reddy; Peter F Kador
Aldose reductase in human retinal pigment epithelial cells.
Experimental eye research 1993;57(2):235-41.
1993: T Yokoyama; Li-Ren Lin; B Chakrapani; Venkat N Reddy
Hypertonic stress increases NaK ATPase, taurine, and myoinositol in human lens and retinal pigment epithelial cultures.
Investigative ophthalmology & visual science 1993;34(8):2512-7.
1993: Li-Ren Lin; Deborah A Carper; T Yokoyama; Venkat N Reddy
The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium.
Investigative ophthalmology & visual science 1993;34(7):2352-9.
1993: N Pozdnyakov; A Lloyd; Venkat N Reddy; Ari Sitaramayya
Nitric oxide-regulated endogenous ADP-ribosylation of rod outer segment proteins.
Biochemical and biophysical research communications 1993;192(2):610-5.
1993: T Arita; Y Murata; Li-Ren Lin; T Tsuji; Venkat N Reddy
Synthesis of lens capsule in long-term culture of human lens epithelial cells.
Investigative ophthalmology & visual science 1993;34(2):355-62.
1992: T Tsuji; Li-Ren Lin; Y Murata; Venkat N Reddy
Immunohistochemical localization of Na,K-ATPase in the in situ lens, cultured human lens epithelium and lentoid.
Experimental eye research 1992;55(3):469-78.
1992: Venkat N Reddy; Li-Ren Lin; Frank J Giblin; B Chakrapani; T Yokoyama
Study of the polyol pathway and cell permeability changes in human lens and retinal pigment epithelium in tissue culture.
Investigative ophthalmology & visual science 1992;33(7):2334-9.
1992: Venkat N Reddy; Li-Ren Lin; Frank J Giblin; Marjorie F Lou; Peter F Kador; J H Kinoshita
The efficacy of aldose reductase inhibitors on polyol accumulation in human lens and retinal pigment epithelium in tissue culture.
Journal of ocular pharmacology 1992;8(1):43-52.
1991: Venkat N Reddy; H Katsura; T Arita; Li-Ren Lin; G Eguchi; K Agata; K Sawada
Study of crystallin expression in human lens epithelial cells during differentiation in culture and in non-lenticular tissues.
Experimental eye research 1991;53(3):367-74.
1991: R L Zhang; D A Samuelson; Z G Zhang; Venkat N Reddy; Barkur S Shastry
Analysis of eye lens-specific genes in congenital hereditary cataracts and microphthalmia of the miniature schnauzer dog.
Investigative ophthalmology & visual science 1991;32(9):2662-5.
1991: Li-Ren Lin; Venkat N Reddy; Frank J Giblin; Peter F Kador; J H Kinoshita
Polyol accumulation in cultured human lens epithelial cells.
Experimental eye research 1991;52(1):93-100.
1990: T Arita; Li-Ren Lin; S R Susan; Venkat N Reddy
Enhancement of differentiation of human lens epithelium in tissue culture by changes in cell-substrate adhesion.
Investigative ophthalmology & visual science 1990;31(11):2395-404.
1990: Barkur S Shastry; Venkat N Reddy
Isolation and characterization of a distantly related member of the beta-gamma crystallin super gene family from Xenopus.
Biochemical and biophysical research communications 1990;171(3):1333-7.
1990: Barkur S Shastry; Venkat N Reddy
The structure and expression of a distantly related member of the beta-gamma crystallin super gene family from Xenopus.
Biochemical and biophysical research communications 1990;171(3):1338-43.
1990: Frank J Giblin; John R Reddan; L Schrimscher; Dorothy Dziedzic; Venkat N Reddy
The relative roles of the glutathione redox cycle and catalase in the detoxification of H2O2 by cultured rabbit lens epithelial cells.
Experimental eye research 1990;50(6):795-804.
1990: Venkat N Reddy
Glutathione and its function in the lens--an overview.
Experimental eye research 1990;50(6):771-8.
1989: Vanita A Padgaonkar; Frank J Giblin; Venkat N Reddy
Disulfide cross-linking of urea-insoluble proteins in rabbit lenses treated with hyperbaric oxygen.
Experimental eye research 1989;49(5):887-99.
1989: H Ikebe; S R Susan; Frank J Giblin; John R Reddan; Venkat N Reddy
Effect of inhibition of the glutathione redox cycle on the ultrastructure of peroxide-treated rabbit epithelial cells.
Experimental eye research 1989;48(3):421-32.
1989: Venkat N Reddy; H Ikebe; Frank J Giblin; John I Clark; John Livesey
Effect of radioprotective agents on X-ray cataracts.
Lens and eye toxicity research 1989;6(4):573-88.
1988: T Arita; Li-Ren Lin; Venkat N Reddy
Differentiation of human lens epithelial cells in tissue culture.
Experimental eye research 1988;47(6):905-10.
1988: Venkat N Reddy; Li-Ren Lin; T Arita; J. SAMUEL ZIGLER; Q L Huang
Crystallins and their synthesis in human lens epithelial cells in tissue culture.
Experimental eye research 1988;47(3):465-78.
1988: Frank J Giblin; L Schrimscher; B Chakrapani; Venkat N Reddy
Exposure of rabbit lens to hyperbaric oxygen in vitro: regional effects on GSH level.
Investigative ophthalmology & visual science 1988;29(8):1312-9.
1988: John R Reddan; Frank J Giblin; Dorothy Dziedzic; J P McCready; L Schrimscher; Venkat N Reddy
Influence of the activity of glutathione reductase on the response of cultured lens epithelial cells from young and old rabbits to hydrogen peroxide.
Experimental eye research 1988;46(2):209-21.
1988: Venkat N Reddy; R Garadi; B Chakrapani; Frank J Giblin
Effect of glutathione depletion on cation transport and metabolism in the rabbit lens.
Ophthalmic research 1988;20(3):191-9.
1987: Frank J Giblin; J P McCready; L Schrimscher; Venkat N Reddy
Peroxide-induced effects on lens cation transport following inhibition of glutathione reductase activity in vitro.
Experimental eye research 1987;45(1):77-91.
1987: R Garadi; Frank J Giblin; Venkat N Reddy
Disulfide-linked membrane proteins in X-ray-induced cataract.
Ophthalmic research 1987;19(3):141-9.
1985: Frank J Giblin; J P McCready; Venkat N Reddy
Response of cultured human lenses to H2O2.
Experimental eye research 1985;41(3):423-6.
1985: Frank J Giblin; J P McCready; John R Reddan; Dorothy Dziedzic; Venkat N Reddy
Detoxification of H2O2 by cultured rabbit lens epithelial cells: participation of the glutathione redox cycle.
Experimental eye research 1985;40(6):827-40.
1984: R Garadi; A R Foltyn; Frank J Giblin; Venkat N Reddy
Protein synthesis in x-irradiated rabbit lens.
Investigative ophthalmology & visual science 1984;25(2):147-52.
1984: Frank J Giblin; J P McCready; T Kodama; Venkat N Reddy
A direct correlation between the levels of ascorbic acid and H2O2 in aqueous humor.
Experimental eye research 1984;38(1):87-93.
1983: R Garadi; Venkat N Reddy; P F Kador; J H Kinoshita
Membrane glycoproteins of Philly mouse lens.
Investigative ophthalmology & visual science 1983;24(9):1321-4.
1982: R Garadi; Frank J Giblin; Venkat N Reddy
Glycoproteins of lens membranes.
Investigative ophthalmology & visual science 1982;22(4):553-7.
1982: Frank J Giblin; J P McCready; Venkat N Reddy
The role of glutathione metabolism in the detoxification of H2O2 in rabbit lens.
Investigative ophthalmology & visual science 1982;22(3):330-5.
1980: K R Hightower; Victor R Leverenz; Venkat N Reddy
Calcium transport in the lens.
Investigative ophthalmology & visual science 1980;19(9):1059-66.