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Pierre Redelinghuys

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Chemicals & Drugs

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Inês Faro-Trindade; Sabelo Hadebe; Ann M Kerrigan; Dirk M Lang; Pierre Redelinghuys; Delyth M Reid; Naren Srinivasan; Chad Steele; Helen Wainwright; Janet A Willment; Gordon D Brown
Characterisation of innate fungal recognition in the lung.
Pierre Redelinghuys; Aristotelis Antonopoulos; Maria A Campanero-Rhodes; Anne Dell; Ten Feizi; Stuart M Haslam; Yan Liu; Emma McKenzie; Paul R Crocker
Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E.
Colin S Anthony; Hazel R Corradi; Sylva L U Schwager; Pierre Redelinghuys; Dimitris Georgiadis; Vincent Dive; K Ravi Acharya; Edward D Sturrock
The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407.

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2012: Inês Faro-Trindade; Sabelo Hadebe; Ann M Kerrigan; Dirk M Lang; Pierre Redelinghuys; Delyth M Reid; Naren Srinivasan; Chad Steele; Helen Wainwright; Janet A Willment; Gordon D Brown
Characterisation of innate fungal recognition in the lung.
PloS one 2012;7(4):e35675.
2011: Pierre Redelinghuys; Aristotelis Antonopoulos; Maria A Campanero-Rhodes; Anne Dell; Ten Feizi; Stuart M Haslam; Yan Liu; Emma McKenzie; Paul R Crocker
Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E.
The Journal of biological chemistry 2011;286(40):34522-32.
2010: Colin S Anthony; Hazel R Corradi; Sylva L U Schwager; Pierre Redelinghuys; Dimitris Georgiadis; Vincent Dive; K Ravi Acharya; Edward D Sturrock
The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407.
The Journal of biological chemistry 2010;285(46):35685-93.
2008: Paul R Crocker; Pierre Redelinghuys
Siglecs as positive and negative regulators of the immune system.
Biochemical Society transactions 2008;36(Pt 6):1467-71.
2008: Hester G O'Neill; Pierre Redelinghuys; Sylva L U Schwager; Edward D Sturrock
The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme.
Biological chemistry 2008;389(9):1153-61.
2006: Aloysius T Nchinda; Kelly Chibale; Pierre Redelinghuys; Edward D Sturrock
Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(17):4612-5.
2006: Aloysius T Nchinda; Kelly Chibale; Pierre Redelinghuys; Edward D Sturrock
Synthesis and molecular modeling of a lisinopril-tryptophan analogue inhibitor of angiotensin I-converting enzyme.
Bioorganic & medicinal chemistry letters 2006;16(17):4616-9.
2006: Zenda L Woodman; Sylva L U Schwager; Pierre Redelinghuys; Anthony Chubb; Elizabeth van der Merwe; Mario R W Ehlers; Edward D Sturrock
Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties.
Biological chemistry 2006;387(8):1043-51.
2006: Pierre Redelinghuys; Aloysius T Nchinda; Kelly Chibale; Edward D Sturrock
Novel ketomethylene inhibitors of angiotensin I-converting enzyme (ACE): inhibition and molecular modelling.
Biological chemistry 2006;387(4):461-6.
2005: Pierre Redelinghuys; Aloysius T Nchinda; Edward D Sturrock
Development of domain-selective angiotensin I-converting enzyme inhibitors.
Annals of the New York Academy of Sciences 2005;1056():160-75.
2005: Zenda L Woodman; Sylva L U Schwager; Pierre Redelinghuys; Adriana K Carmona; Mario R W Ehlers; Edward D Sturrock
The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity.
The Biochemical journal 2005;389(Pt 3):739-44.
2003: Kerry Gordon; Pierre Redelinghuys; Sylva L U Schwager; Mario R W Ehlers; Anastassios C Papageorgiou; Ramanathan Natesh; K Ravi Acharya; Edward D Sturrock
Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme.
The Biochemical journal 2003;371(Pt 2):437-42.